Claims
- 1. A method to promote or stimulate hair growth and/or delay hair loss, said method comprising administering an effective amount of at least one bradykinin antagonist to promote or stimulate hair growth and/or delay hair loss to an individual in need thereof, wherein said bradykinin antagonist binds to a B1 and/or B2 bradykinin receptor.
- 2. A method to promote or stimulate hair growth and/or delay hair loss comprising administering an effective amount of at least one bradykinin antagonist in an amount effective to promote, stimulate and/or delay hair loss wherein said bradykinin antagonist is selected fromD-Arg (Hyp3, D-Phe7)-bradykinin (NPC567); (Thi5,8, D-Phe7)-bradykinin; D-Arg, (Hyp3, Thi5,8, D-Phe7)-bradykinin; N-α-adamantaneacetyl-D-Arg (Hyp3, Thi5,8, D-Phe7)-bradykinin; des-Arg9, (Leu8)-bradykinin; P-guanidobenzoyl (Hyp3, Thi5, D-Tic7, Oic8)-bradykinin (S 16118); D-Arg (Hyp3, Thi5, D-Tic7, Oic8)-bradykinin (HOE 140); and D-Arg, (Hyp3, D-Hype (transpropyl)7, Oic8)-bradykinin (NPC 17731).
- 3. The method of claim 2 wherein said bradykinin antagonist is D-Arg (Hyp3, Thi5, D-Tic7, Oic8)-bradykinin (HOE 140).
- 4. A process for the cosmetic treatment of the hair and/or scalp comprising administering an effective amount of a cosmetic composition wherein said composition comprises at least one bradykinin antagonist in a physiologically acceptable medium, in an amount effective to promote or stimulate hair growth and/or delay hair loss in said subject wherein said bradykinin antagonist binds to a B1 and/or B2 bradykinin receptor.
- 5. The process for cosmetic treatment of the hair and/or scalp of claim 4 wherein said bradykinin antagonist is selected fromD-Arg (Hyp3, D-Phe7)-bradykinin (NPC567); (Thi5,8, D-Phe7)-bradykinin; D-Arg, (Hyp3, Thi5,8, D-Phe7)-bradykinin; N-α-adamantaneacetyl-D-Arg (Hyp3, Thi5,8, D-Phe7)-bradykinin; des-Arg9, (Leu8)-bradykinin; P-guanidobenzoyl (Hyp3, Thi5, D-Tic7, Oic8)-bradykinin (S 16118); D-Arg (Hyp3, Thi5, D-Tic7, Oic8)-bradykinin (HOE 140); and D-Arg, (Hyp3, D-Hype (transpropyl)7, Oic8)-bradykinin (NPC 17731).
- 6. The process for cosmetic treatment of the hair and/or scalp of claim 4 wherein said antagonist is D-Arg (Hyp3, Thi5, D-Tic7, Oic8)-bradykinin (HOE 140).
- 7. The process of claim 4 wherein said cosmetic composition is administered to the hair and/or scalp.
- 8. The process of claim 6 wherein said cosmetic composition is left in contact with the hair and/or scalp.
Priority Claims (1)
Number |
Date |
Country |
Kind |
95 11809 |
Oct 1995 |
FR |
|
CROSS-REFERENCE TO RELATES APPLICATIONS
This application claims benefit of priority under 371 to PCT/FR96/01528, filed on Oct. 1, 1996, which in turn claims benefit of priority to French Patent Application No. 95/11809, filed on Oct. 6, 1995.
PCT Information
Filing Document |
Filing Date |
Country |
Kind |
PCT/FR96/01528 |
|
WO |
00 |
Publishing Document |
Publishing Date |
Country |
Kind |
WO97/13493 |
4/17/1997 |
WO |
A |
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