The present technology relates generally to devices and methods for intravascular treatment of emboli within a blood vessel of a human patient.
Thromboembolism occurs when a thrombus or blood clot trapped within a blood vessel breaks loose and travels through the blood stream to another location in the circulatory system, resulting in a clot or obstruction at the new location. When a clot forms in the venous circulation, it often travels to the lungs via the heart and lodges within a pulmonary blood vessel PV causing a pulmonary embolism PE. A pulmonary embolism can decrease blood flow through the lungs, which in turn causes decreased oxygenation of the lungs, heart and rest of the body. Moreover, pulmonary embolisms can cause the right ventricle of the heart to pump harder to provide sufficient blood to the pulmonary blood vessels, which can cause right ventricle dysfunction (dilation), and heart failure in more extreme cases.
Conventional approaches to treating thromboembolism and/or pulmonary embolism include clot reduction and/or removal. For example, anticoagulants can be introduced to the affected vessel to prevent additional clots from forming, and thrombolytics can be introduced to the vessel to at least partially disintegrate the clot. However, such agents typically take a prolonged period of time (e.g., hours, days, etc.) before the treatment is effective and in some instances can cause hemorrhaging. Transcatheter clot removal devices also exist, however, such devices are typically highly complex, prone to cause trauma to the vessel, hard to navigate to the pulmonary embolism site, and/or expensive to manufacture. Conventional approaches also include surgical techniques that involve opening the chest cavity and dissecting the pulmonary vessel. Such surgical procedures, however, come with increased cost, procedure time, risk of infection, higher morbidity, higher mortality, and recovery time. Accordingly, there is a need for devices and methods that address one or more of these deficiencies.
Many aspects of the present technology can be better understood with reference to the following drawings. The components in the drawings are not necessarily to scale. Instead, emphasis is placed on illustrating clearly the principles of the present disclosure.
Specific details of several embodiments of clot treatment devices, systems and associated methods in accordance with the present technology are described below with reference to
With regard to the terms “distal” and “proximal” within this description, unless otherwise specified, the terms can reference a relative position of the portions of a clot treatment device and/or an associated delivery device with reference to an operator and/or a location in the vasculature.
In the delivery state shown in
In some embodiments the treatment portions 203 can be fabricated from a single tube (e.g., a hypotube). A plurality of elongated slits may be cut or machined through the wall of the tube by various means known in the art (e.g., conventional machining, laser cutting, electrical discharge machining, photochemical machining, etc.) to form a plurality of clot engagement members 202 that are integral with the corresponding hub 206. In some embodiments, the tube can be cut such that individual clot engagement members 202 can have non-circular cross-sections. The cut tube may then be formed by heat treatment to move from the delivery state shown in
Referring still to
For example, as shown in
Referring to
Advantageously, clot engagement members 202 having shorter radially furthest apex distances D and/or shorter lengths L can have a greater radial stiffness than clot engagement members 202 having longer radially furthest apex distances D and/or longer lengths L. As shown in the isolated side view of a clot engagement member of
The clot engagement members 202 can have a single or constant radius of curvature. In other embodiments, the clot engagement members 202 can have a plurality of radii of curvature, such as a first region with a first radius of curvature and a second region with a second radius of curvature. In some embodiments, the clot engagement members 202 can have a single radius of curvature that is the same for all of the clot engagement members 202. In other embodiments, the clot treatment device 200 can have a first group of clot engagement members 202 with a constant radius of curvature and a second group of clot engagement members 202 with a plurality of radii of curvature. Moreover, in additional embodiments the clot treatment device 200 can include a first group of clot engagement members 202 having a first radius of curvature and a second group of clot engagement members 202 having a second radius of curvature different than the first radius of curvature. In some embodiments, the radius of the clot engagement members 202 can be between about 1.5 mm and about 12 mm, and in some embodiments, between about 2 mm and about 12 mm.
The clot engagement members 402 can be arranged in rows such that adjacent rows along the support member 404 alternate between long 407 and short 409 clot engagement members. Additionally, the short clot engagement members 409 can be circumferentially aligned with the long 407 clot engagement members 407 about the support member 404. In other embodiments, the clot engagement members 402 can have other suitable arrangements and/or configurations. For example, in some embodiments, one or more of the short clot engagement members 409 can be circumferentially offset from one or more of the long clot engagement members 409 about the support member 404, the long and short clot engagement members 407, 409 can be within the same rows, additionally or alternatively arranged in columns, and/or randomly positioned along or about the support member 404.
In certain procedures, it may be advantageous to move the clot treatment device along the vessel (fully or partially within the embolism) in both the upstream and downstream directions to facilitate engagement and/or disruption of a clot or thrombus by the clot engagement members. During such procedures, it may be advantageous to include one or more distally-facing clot engagement members to enhance engagement and/or disruption of the clot material. Accordingly, the clot treatment devices of the present technology can include both proximally-facing clot engagement members and distally-facing clot engagement members. For example,
In any of the clot treatment device embodiments that comprise a central tube member, the inner tube or “tether tube” may be constructed so as to have spring properties. For example, as shown in
Now referring to
Some embodiments described here may be particularly useful for the treatment of deep vein thrombosis. (See
Percutaneous access for endovascular interventions is most often achieved in the vein distal to the occluded segment. For isolated iliac DVT, an ipsilateral common femoral puncture is most appropriate. Alternatively, a retrograde approach from either the jugular, iliac vein or the contralateral femoral vein may be used for isolated iliac and femoral vein DVT. More commonly, however, patients present with more extensive iliofemoral or iliofemoral popliteal thrombosis, in which case access is best obtained from the ipsilateral popliteal vein while the patient is positioned prone. Ultrasound guidance may be used for access of the popliteal or tibial veins and for any access obtained while the patient is fully anticoagulated. Further, a micropucture technique with a 22-gauge needle and 0.014-inch guidewire may minimize bleeding complications and vessel wall trauma. Following initial access, the thrombus is crossed with a guidewire to facilitate catheter or device positioning. For a lower puncture location (i.e., closer to the feet) such as the popliteal, a suitable (e.g., less than 10 F) catheter introducer sheath (such as a Flexor® manufactured by Cook, Inc. of Bloomington, Ind.) may be introduced into the vein over a guidewire. If alternate access is done for a retrograde approach to the thrombosis, a larger introducer (up to about 22 F) may be used. If a downstream access is made and then a retrograde approach to the thrombus is done, an expandable tip catheter such as that shown in
The following examples are illustrative of several embodiments of the present technology:
1. A clot treatment device for treating an embolism within a blood vessel, the clot treatment device comprising:
2. The clot treatment device of example 1, further comprising:
3. The clot treatment device of any of examples 1 or 2 wherein:
4. The clot treatment device of any of examples 1-3 wherein the first clot engagement members have a first stiffness and the second clot engagement members have a second stiffness greater than the first stiffness.
5. The clot treatment device of any of examples 1-4 wherein:
6. The clot treatment device of any of examples 1-5, further comprising:
7. The clot treatment device of example 6, further comprising:
8. The clot treatment device of example 7 wherein:
9. The clot treatment device of any of examples 1-5 and 7, further comprising:
10. The clot treatment device of any of examples 1-5 and 7, further comprising:
11. A treatment device for treating an embolism within a blood vessel, the clot treatment device moveable between a low-profile undeployed state and a deployed state, the clot treatment device comprising:
12. The clot treatment device of example 11 wherein the curved portion further includes an end section that curves radially inwardly from the proximally extending section.
13. The clot treatment device of any of examples 11-12 wherein, in the undeployed state:
14. The clot treatment device of any of examples 11-13, further comprising:
The above detailed descriptions of embodiments of the present technology are for purposes of illustration only and are not intended to be exhaustive or to limit the present technology to the precise form(s) disclosed above. Various equivalent modifications are possible within the scope of the present technology, as those skilled in the relevant art will recognize. For example, while steps may be presented in a given order, alternative embodiments may perform steps in a different order. The various embodiments described herein and elements thereof may also be combined to provide further embodiments. In some cases, well-known structures and functions have not been shown or described in detail to avoid unnecessarily obscuring the description of embodiments of the present technology.
From the foregoing, it will be appreciated that specific embodiments of the technology have been described herein for purposes of illustration, but well-known structures and functions have not been shown or described in detail to avoid unnecessarily obscuring the description of the embodiments of the technology. Where the context permits, singular or plural terms may also include the plural or singular term, respectively.
Certain aspects of the present technology may take the form of computer-executable instructions, including routines executed by a controller or other data processor. In some embodiments, a controller or other data processor is specifically programmed, configured, and/or constructed to perform one or more of these computer-executable instructions. Furthermore, some aspects of the present technology may take the form of data (e.g., non-transitory data) stored or distributed on computer-readable media, including magnetic or optically readable and/or removable computer discs as well as media distributed electronically over networks. Accordingly, data structures and transmissions of data particular to aspects of the present technology are encompassed within the scope of the present technology. The present technology also encompasses methods of both programming computer-readable media to perform particular steps and executing the steps.
Moreover, unless the word “or” is expressly limited to mean only a single item exclusive from the other items in reference to a list of two or more items, then the use of “or” in such a list is to be interpreted as including (a) any single item in the list, (b) all of the items in the list, or (c) any combination of the items in the list. Additionally, the term “comprising” is used throughout to mean including at least the recited feature(s) such that any greater number of the same feature and/or additional types of other features are not precluded. It will also be appreciated that specific embodiments have been described herein for purposes of illustration, but that various modifications may be made without deviating from the technology. Further, while advantages associated with certain embodiments of the technology have been described in the context of those embodiments, other embodiments may also exhibit such advantages, and not all embodiments need necessarily exhibit such advantages to fall within the scope of the technology. Accordingly, the disclosure and associated technology can encompass other embodiments not expressly shown or described herein.
This is a continuation of U.S. patent application Ser. No. 15/031,102, filed Apr. 21, 2016, which is a 35 U.S.C. § 371 U.S. National Phase Application of International Application No. PCT/US2014/061645, filed Oct. 21, 2014, which is a continuation-in-part of U.S. patent application Ser. No. 14/299,933, filed Jun. 9, 2014, now U.S. Pat. No. 9,259,237, and a continuation-in-part of U.S. patent application Ser. No. 14/299,997, filed Jun. 9, 2014, which claims benefit U.S. Provisional Patent Application No. 61/949,953, filed Mar. 7, 2014, and U.S. Provisional Patent Application No. 61/893,859, filed Oct. 21, 2013, all of which are incorporated herein by reference in their entireties.
Number | Name | Date | Kind |
---|---|---|---|
2846179 | Monckton | Aug 1958 | A |
3088363 | Sparks | May 1963 | A |
3197173 | Taubenheim | Jul 1965 | A |
3435826 | Fogarty | Apr 1969 | A |
3892161 | Sokol | Jul 1975 | A |
3923065 | Nozick et al. | Dec 1975 | A |
4030503 | Clark, III | Jun 1977 | A |
4034642 | Iannucci et al. | Jul 1977 | A |
4287808 | Leonard et al. | Sep 1981 | A |
4393872 | Reznik et al. | Jul 1983 | A |
4523738 | Raftis et al. | Jun 1985 | A |
4551862 | Haber | Nov 1985 | A |
4650466 | Luther | Mar 1987 | A |
4873978 | Ginsburg | Oct 1989 | A |
4883458 | Shiber | Nov 1989 | A |
4890611 | Monfort et al. | Jan 1990 | A |
4960259 | Sunnanvader et al. | Oct 1990 | A |
4978341 | Niederhauser | Dec 1990 | A |
5011488 | Ginsburg | Apr 1991 | A |
5059178 | Ya | Oct 1991 | A |
5102415 | Guenther et al. | Apr 1992 | A |
5127626 | Hilal et al. | Jul 1992 | A |
5129910 | Phan et al. | Jul 1992 | A |
5192286 | Phan et al. | Mar 1993 | A |
5192290 | Hilal | Mar 1993 | A |
5360417 | Gravener et al. | Nov 1994 | A |
5370653 | Cragg | Dec 1994 | A |
5476450 | Ruggio | Dec 1995 | A |
5490859 | Mische et al. | Feb 1996 | A |
5591137 | Stevens | Jan 1997 | A |
5746758 | Nordgren et al. | May 1998 | A |
5749858 | Cramer | May 1998 | A |
5766191 | Trerotola | Jun 1998 | A |
5782817 | Franzel et al. | Jul 1998 | A |
5827229 | Auth et al. | Oct 1998 | A |
5827304 | Hart | Oct 1998 | A |
5868708 | Hart et al. | Feb 1999 | A |
5873866 | Kondo et al. | Feb 1999 | A |
5873882 | Straub et al. | Feb 1999 | A |
5876414 | Straub | Mar 1999 | A |
5882329 | Patterson et al. | Mar 1999 | A |
5911710 | Barry et al. | Jun 1999 | A |
5972019 | Engelson et al. | Oct 1999 | A |
5974938 | Lloyd | Nov 1999 | A |
5989233 | Yoon | Nov 1999 | A |
5993483 | Gianotti | Nov 1999 | A |
6066149 | Samson et al. | May 2000 | A |
6221006 | Dubrul et al. | Apr 2001 | B1 |
6228060 | Howell | May 2001 | B1 |
6238412 | Dubrul et al. | May 2001 | B1 |
6254571 | Hart | Jul 2001 | B1 |
6258115 | Dubrul | Jul 2001 | B1 |
6306163 | Fitz | Oct 2001 | B1 |
6350271 | Kurz et al. | Feb 2002 | B1 |
6364895 | Greenhalgh | Apr 2002 | B1 |
6368339 | Amplatz | Apr 2002 | B1 |
6383205 | Samson et al. | May 2002 | B1 |
6413235 | Parodi | Jul 2002 | B1 |
6423032 | Parodi | Jul 2002 | B2 |
6440148 | Shiber | Aug 2002 | B1 |
6454741 | Muni et al. | Sep 2002 | B1 |
6454775 | Demarais et al. | Sep 2002 | B1 |
6458103 | Albert et al. | Oct 2002 | B1 |
6458139 | Palmer et al. | Oct 2002 | B1 |
6511492 | Rosenbluth et al. | Jan 2003 | B1 |
6514273 | Voss et al. | Feb 2003 | B1 |
6530935 | Wensel et al. | Mar 2003 | B2 |
6530939 | Hopkins et al. | Mar 2003 | B1 |
6544279 | Hopkins et al. | Apr 2003 | B1 |
6551342 | Shen et al. | Apr 2003 | B1 |
6589263 | Hopkins et al. | Jul 2003 | B1 |
6596011 | Johnson et al. | Jul 2003 | B2 |
6602271 | Adams et al. | Aug 2003 | B2 |
6605074 | Zadno-Azizi et al. | Aug 2003 | B2 |
6605102 | Mazzocchi et al. | Aug 2003 | B1 |
6623460 | Heck | Sep 2003 | B1 |
6635070 | Leeflang et al. | Oct 2003 | B2 |
6645222 | Parodi et al. | Nov 2003 | B1 |
6660013 | Rabiner et al. | Dec 2003 | B2 |
6663650 | Sepetka et al. | Dec 2003 | B2 |
6685722 | Rosenbluth et al. | Feb 2004 | B1 |
6692504 | Kurz et al. | Feb 2004 | B2 |
6699260 | Dubrul et al. | Mar 2004 | B2 |
6755847 | Eskuri | Jun 2004 | B2 |
6767353 | Shiber | Jul 2004 | B1 |
6800080 | Bates | Oct 2004 | B1 |
6824553 | Gene et al. | Nov 2004 | B1 |
6939361 | Kleshinski | Sep 2005 | B1 |
6960222 | Vo et al. | Nov 2005 | B2 |
7004954 | Voss et al. | Feb 2006 | B1 |
7036707 | Aota et al. | May 2006 | B2 |
7041084 | Fojtik | May 2006 | B2 |
7052500 | Bashiri et al. | May 2006 | B2 |
7056328 | Arnott | Jun 2006 | B2 |
7069835 | Nishri et al. | Jul 2006 | B2 |
7094249 | Thomas et al. | Aug 2006 | B1 |
7179273 | Palmer et al. | Feb 2007 | B1 |
7220269 | Ansel et al. | May 2007 | B1 |
7232432 | Fulton, III et al. | Jun 2007 | B2 |
7244243 | Lary | Jul 2007 | B2 |
7285126 | Sepetka et al. | Oct 2007 | B2 |
7306618 | Demond et al. | Dec 2007 | B2 |
7320698 | Eskuri | Jan 2008 | B2 |
7323002 | Johnson et al. | Jan 2008 | B2 |
7331980 | Dubrul et al. | Feb 2008 | B2 |
7534234 | Fojtik | May 2009 | B2 |
7578830 | Kusleika et al. | Aug 2009 | B2 |
7621870 | Berrada et al. | Nov 2009 | B2 |
7674247 | Fojtik | Mar 2010 | B2 |
7691121 | Rosenbluth et al. | Apr 2010 | B2 |
7695458 | Belley et al. | Apr 2010 | B2 |
7763010 | Evans et al. | Jul 2010 | B2 |
7766934 | Pal et al. | Aug 2010 | B2 |
7775501 | Kees | Aug 2010 | B2 |
7905877 | Oscar et al. | Mar 2011 | B1 |
7905896 | Straub | Mar 2011 | B2 |
7938809 | Lampropoulos et al. | May 2011 | B2 |
7938820 | Webster et al. | May 2011 | B2 |
7967790 | Whiting et al. | Jun 2011 | B2 |
7976511 | Fojtik | Jul 2011 | B2 |
7993302 | Hebert et al. | Aug 2011 | B2 |
7993363 | Demond et al. | Aug 2011 | B2 |
8043313 | Krolik et al. | Oct 2011 | B2 |
8052640 | Fiorella et al. | Nov 2011 | B2 |
8066757 | Ferrera et al. | Nov 2011 | B2 |
8070791 | Ferrera et al. | Dec 2011 | B2 |
8075510 | Aklog et al. | Dec 2011 | B2 |
8088140 | Ferrera et al. | Jan 2012 | B2 |
8100935 | Rosenbluth et al. | Jan 2012 | B2 |
8109962 | Pal | Feb 2012 | B2 |
8118829 | Carrison et al. | Feb 2012 | B2 |
8197493 | Ferrera et al. | Jun 2012 | B2 |
8246641 | Osborne et al. | Aug 2012 | B2 |
8261648 | Marchand et al. | Sep 2012 | B1 |
8267897 | Wells | Sep 2012 | B2 |
8298257 | Sepetka et al. | Oct 2012 | B2 |
8317748 | Fiorella et al. | Nov 2012 | B2 |
8337450 | Fojtik | Dec 2012 | B2 |
RE43902 | Hopkins et al. | Jan 2013 | E |
8357178 | Grandfield et al. | Jan 2013 | B2 |
8361104 | Jones et al. | Jan 2013 | B2 |
8409215 | Sepetka et al. | Apr 2013 | B2 |
8486105 | Demond et al. | Jul 2013 | B2 |
8491539 | Fojtik | Jul 2013 | B2 |
8512352 | Martin | Aug 2013 | B2 |
8535334 | Martin | Sep 2013 | B2 |
8545526 | Martin et al. | Oct 2013 | B2 |
8568432 | Straub | Oct 2013 | B2 |
8574262 | Ferrera et al. | Nov 2013 | B2 |
8579915 | French et al. | Nov 2013 | B2 |
8585713 | Ferrera et al. | Nov 2013 | B2 |
8696622 | Fiorella et al. | Apr 2014 | B2 |
8715314 | Janardhan | May 2014 | B1 |
8771289 | Mohiuddin et al. | Jul 2014 | B2 |
8777893 | Malewicz | Jul 2014 | B2 |
8784434 | Rosenbluth et al. | Jul 2014 | B2 |
8784441 | Rosenbluth et al. | Jul 2014 | B2 |
8795305 | Martin et al. | Aug 2014 | B2 |
8795345 | Grandfield et al. | Aug 2014 | B2 |
8801748 | Martin | Aug 2014 | B2 |
8814927 | Shin et al. | Aug 2014 | B2 |
8820207 | Marchand et al. | Sep 2014 | B2 |
8826791 | Thompson et al. | Sep 2014 | B2 |
8828044 | Aggerholm et al. | Sep 2014 | B2 |
8833224 | Thompson et al. | Sep 2014 | B2 |
8845621 | Fojtik | Sep 2014 | B2 |
8852205 | Brady et al. | Oct 2014 | B2 |
8852226 | Gilson et al. | Oct 2014 | B2 |
8932319 | Martin et al. | Jan 2015 | B2 |
8939991 | Krolik et al. | Jan 2015 | B2 |
8945143 | Ferrera et al. | Feb 2015 | B2 |
8945172 | Ferrera et al. | Feb 2015 | B2 |
8968330 | Rosenbluth et al. | Mar 2015 | B2 |
8992504 | Castella et al. | Mar 2015 | B2 |
9005172 | Chung | Apr 2015 | B2 |
9101382 | Krolik et al. | Aug 2015 | B2 |
9149609 | Ansel et al. | Oct 2015 | B2 |
9161766 | Slee et al. | Oct 2015 | B2 |
9204887 | Cully et al. | Dec 2015 | B2 |
9259237 | Quick et al. | Feb 2016 | B2 |
9283066 | Hopkins et al. | Mar 2016 | B2 |
9408620 | Rosenbluth | Aug 2016 | B2 |
9439664 | Sos | Sep 2016 | B2 |
9439751 | White et al. | Sep 2016 | B2 |
9456834 | Folk | Oct 2016 | B2 |
9463036 | Brady et al. | Oct 2016 | B2 |
9526864 | Quick | Dec 2016 | B2 |
9526865 | Quick | Dec 2016 | B2 |
9566424 | Pessin | Feb 2017 | B2 |
9579116 | Nguyen et al. | Feb 2017 | B1 |
9616213 | Furnish et al. | Apr 2017 | B2 |
9636206 | Nguyen et al. | May 2017 | B2 |
9700332 | Marchand et al. | Jul 2017 | B2 |
9717519 | Rosenbluth et al. | Aug 2017 | B2 |
9744024 | Nguyen et al. | Aug 2017 | B2 |
9757137 | Krolik et al. | Sep 2017 | B2 |
9844386 | Nguyen et al. | Dec 2017 | B2 |
9844387 | Marchand et al. | Dec 2017 | B2 |
9884387 | Plha et al. | Feb 2018 | B2 |
9999493 | Nguyen et al. | Jun 2018 | B2 |
10004531 | Rosenbluth et al. | Jun 2018 | B2 |
10045790 | Cox et al. | Aug 2018 | B2 |
1009865 | Marchand et al. | Oct 2018 | A1 |
10098651 | Marchand et al. | Oct 2018 | B2 |
1023840 | Cox et al. | Mar 2019 | A1 |
10335186 | Rosenbluth et al. | Jul 2019 | B2 |
10342571 | Marchand et al. | Jul 2019 | B2 |
10349960 | Quick | Jul 2019 | B2 |
1052481 | Marchand et al. | Jan 2020 | A1 |
10912577 | Marchand et al. | Feb 2021 | B2 |
20010004699 | Gittings et al. | Jun 2001 | A1 |
20010041909 | Tsugita et al. | Nov 2001 | A1 |
20010051810 | Dubrul et al. | Dec 2001 | A1 |
20020111648 | Kusleika et al. | Aug 2002 | A1 |
20020120277 | Hauschild et al. | Aug 2002 | A1 |
20020147458 | Hiblar et al. | Oct 2002 | A1 |
20020156457 | Fisher | Oct 2002 | A1 |
20030114875 | Sjostrom | Jun 2003 | A1 |
20030116731 | Hartley | Jun 2003 | A1 |
20030125663 | Coleman et al. | Jul 2003 | A1 |
20030135230 | Massey et al. | Jul 2003 | A1 |
20030153973 | Soun et al. | Aug 2003 | A1 |
20040039412 | Isshiki et al. | Feb 2004 | A1 |
20040073243 | Sepetka et al. | Apr 2004 | A1 |
20040199202 | Dubrul | Oct 2004 | A1 |
20050038468 | Panetta et al. | Feb 2005 | A1 |
20050119668 | Teague et al. | Jun 2005 | A1 |
20050283186 | Berrada et al. | Dec 2005 | A1 |
20060047286 | West | Mar 2006 | A1 |
20060100662 | Daniel et al. | May 2006 | A1 |
20060247500 | Voegele et al. | Nov 2006 | A1 |
20060253145 | Lucas | Nov 2006 | A1 |
20060282111 | Morsi | Dec 2006 | A1 |
20070038225 | Osborne | Feb 2007 | A1 |
20070112374 | Paul, Jr. et al. | May 2007 | A1 |
20070118165 | DeMello et al. | May 2007 | A1 |
20070161963 | Smalling | Jul 2007 | A1 |
20070179513 | Deutsch | Aug 2007 | A1 |
20070191866 | Palmer et al. | Aug 2007 | A1 |
20070198028 | Miloslayski et al. | Aug 2007 | A1 |
20070208361 | Okushi et al. | Sep 2007 | A1 |
20070208367 | Fiorella et al. | Sep 2007 | A1 |
20070213753 | Waller | Sep 2007 | A1 |
20070255252 | Mehta | Nov 2007 | A1 |
20080015541 | Rosenbluth et al. | Jan 2008 | A1 |
20080088055 | Ross | Apr 2008 | A1 |
20080157017 | Macatangay et al. | Jul 2008 | A1 |
20080167678 | Morsi | Jul 2008 | A1 |
20080228209 | DeMello et al. | Sep 2008 | A1 |
20080234722 | Bonnette et al. | Sep 2008 | A1 |
20080262528 | Martin | Oct 2008 | A1 |
20080269798 | Ramzipoor et al. | Oct 2008 | A1 |
20080300466 | Gresham | Dec 2008 | A1 |
20090018566 | Escudero et al. | Jan 2009 | A1 |
20090054918 | Henson | Feb 2009 | A1 |
20090062841 | Amplatz et al. | Mar 2009 | A1 |
20090160112 | Ostrovsky | Jun 2009 | A1 |
20090163846 | Aklog et al. | Jun 2009 | A1 |
20090182362 | Thompson et al. | Jul 2009 | A1 |
20090281525 | Harding et al. | Nov 2009 | A1 |
20090292307 | Razack | Nov 2009 | A1 |
20100087850 | Razack | Apr 2010 | A1 |
20100114113 | Dubrul et al. | May 2010 | A1 |
20100121312 | Gielenz et al. | May 2010 | A1 |
20100204712 | Mallaby | Aug 2010 | A1 |
20100249815 | Jantzen et al. | Sep 2010 | A1 |
20100268264 | Bonnette | Oct 2010 | A1 |
20100318178 | Rapaport et al. | Dec 2010 | A1 |
20110054405 | Whiting et al. | Mar 2011 | A1 |
20110060212 | Slee et al. | Mar 2011 | A1 |
20110144592 | Wong et al. | Jun 2011 | A1 |
20110152993 | Marchand et al. | Jun 2011 | A1 |
20110190806 | Wittens | Aug 2011 | A1 |
20110213290 | Chin et al. | Sep 2011 | A1 |
20110213403 | Aboytes | Sep 2011 | A1 |
20110224707 | Miloslayski et al. | Sep 2011 | A1 |
20110245807 | Sakata et al. | Oct 2011 | A1 |
20110251629 | Galdonik et al. | Oct 2011 | A1 |
20110264133 | Hanlon et al. | Oct 2011 | A1 |
20110319917 | Ferrera et al. | Dec 2011 | A1 |
20120059356 | di Palma | Mar 2012 | A1 |
20120089216 | Rapaport et al. | Apr 2012 | A1 |
20120101480 | Ingle et al. | Apr 2012 | A1 |
20120101510 | Lenker et al. | Apr 2012 | A1 |
20120138832 | Townsend | Jun 2012 | A1 |
20120143239 | Aklog et al. | Jun 2012 | A1 |
20120165919 | Cox et al. | Jun 2012 | A1 |
20120179181 | Straub et al. | Jul 2012 | A1 |
20120232655 | Lorrison et al. | Sep 2012 | A1 |
20120271231 | Agrawal | Oct 2012 | A1 |
20120310166 | Huff | Dec 2012 | A1 |
20130092012 | Marchand et al. | Apr 2013 | A1 |
20130184703 | Brice et al. | Jul 2013 | A1 |
20140005713 | Bowman | Jan 2014 | A1 |
20140025048 | Ward | Jan 2014 | A1 |
20140276403 | Follmer et al. | Sep 2014 | A1 |
20140371779 | Vale et al. | Dec 2014 | A1 |
20150018860 | Quick et al. | Jan 2015 | A1 |
20150133990 | Davidson | May 2015 | A1 |
20150196744 | Aboytes | Jul 2015 | A1 |
20150238207 | Cox et al. | Aug 2015 | A1 |
20150265299 | Cooper et al. | Sep 2015 | A1 |
20150305756 | Rosenbluth et al. | Oct 2015 | A1 |
20150305859 | Eller | Oct 2015 | A1 |
20150352325 | Quick | Dec 2015 | A1 |
20150360001 | Quick | Dec 2015 | A1 |
20150374391 | Quick et al. | Dec 2015 | A1 |
20160113666 | Quick et al. | Apr 2016 | A1 |
20160143721 | Rosenbluth et al. | May 2016 | A1 |
20160262790 | Rosenbluth et al. | Sep 2016 | A1 |
20160277276 | Cox et al. | Oct 2016 | A1 |
20170037548 | Lee | Feb 2017 | A1 |
20170058623 | Jaffrey et al. | Mar 2017 | A1 |
20170105745 | Rosenbluth et al. | Apr 2017 | A1 |
20170112513 | Marchand et al. | Apr 2017 | A1 |
20170112514 | Marchand et al. | Apr 2017 | A1 |
20170189041 | Cox et al. | Jul 2017 | A1 |
20170233908 | Kroczynski et al. | Aug 2017 | A1 |
20170265878 | Marchand et al. | Sep 2017 | A1 |
20170325839 | Rosenbluth et al. | Nov 2017 | A1 |
20180064454 | Losordo et al. | Mar 2018 | A1 |
20180092652 | Marchand et al. | Apr 2018 | A1 |
20180105963 | Quick | Apr 2018 | A1 |
20180125512 | Nguyen et al. | May 2018 | A1 |
20180193043 | Marchand et al. | Jul 2018 | A1 |
20180256178 | Cox et al. | Sep 2018 | A1 |
20180296240 | Rosenbluth et al. | Oct 2018 | A1 |
20180344339 | Cox et al. | Dec 2018 | A1 |
20180361116 | Quick et al. | Dec 2018 | A1 |
20190000492 | Casey et al. | Jan 2019 | A1 |
20190046219 | Marchand et al. | Feb 2019 | A1 |
20190070401 | Merritt et al. | Mar 2019 | A1 |
20190231373 | Quick | Aug 2019 | A1 |
Number | Date | Country |
---|---|---|
103932756 | Jul 2014 | CN |
102017004383 | Jul 2018 | DE |
6190049 | Jul 1994 | JP |
2001522631 | May 1999 | JP |
2004097807 | Apr 2004 | JP |
2005230132 | Sep 2005 | JP |
2005323702 | Nov 2005 | JP |
2006094876 | Apr 2006 | JP |
2011526820 | Jan 2010 | JP |
WO-1997017889 | May 1997 | WO |
WO-1999044542 | Sep 1999 | WO |
WO-2000053120 | Sep 2000 | WO |
WO2004018916 | Mar 2004 | WO |
WO-2005046736 | May 2005 | WO |
WO-2006110186 | Oct 2006 | WO |
WO-2007092820 | Aug 2007 | WO |
WO-2009155571 | Dec 2009 | WO |
WO2010002549 | Jan 2010 | WO |
WO-2010010545 | Jan 2010 | WO |
WO-2010023671 | Mar 2010 | WO |
WO-2010049121 | May 2010 | WO |
WO-2010102307 | Sep 2010 | WO |
WO2011032712 | Mar 2011 | WO |
WO-2011054531 | May 2011 | WO |
WO-2012009675 | Jan 2012 | WO |
WO-2012011097 | Apr 2012 | WO |
WO-2012065748 | May 2012 | WO |
WO2012120490 | Sep 2012 | WO |
WO-2014047650 | Mar 2014 | WO |
WO-2014081892 | May 2014 | WO |
WO-2015006782 | Jan 2015 | WO |
WO-2015061365 | Apr 2015 | WO |
WO2015121424 | Aug 2015 | WO |
WO2015191646 | Dec 2015 | WO |
WO2017024258 | Feb 2017 | WO |
WO2017070702 | Apr 2017 | WO |
WO2017106877 | Jun 2017 | WO |
WO2018080590 | May 2018 | WO |
WO2019050765 | Mar 2019 | WO |
WO2019075444 | Apr 2019 | WO |
Entry |
---|
European Patent Application No. 13838945.7, Extended European Search Report, 9 pages, dated Apr. 15, 2016. |
Gibbs, et al., “Temporary Stent as a bail-out device during percutaneous transluminal coronary angioplasty: preliminary clinical experience,” British Heart Journal, 1994, 71:372-377, Oct. 12, 1993 6 pgs. |
Goldhaber, S. et al. “Percutaneous Mechanical Thrombectomy for Acute Pulmonary Embolism—a Double-Edged Sword”, American College of CHEST Physicians, Aug. 2007: 132:2, 363-372. |
Goldhaber, S., “Advanced treatment strategies for acute pulmonary embolism, including thrombolysis and embolectomy”, Journal of Thrombosis and Haemostasis, 2009: 7 (Suppl. 1): 322-327. |
Gupta, S. et al., “Acute Pulmonary Embolism Advances in Treatment,” JAPI, Association of Physicians India, Mar. 2008, vol. 56, 185-191. |
International Search Report and Written Opinion for International App. No. PCT/US13/61470, dated Jan. 17, 2014, 7 pages. |
International Search Report and Written Opinion for International App. No. PCT/US2014/046567, dated Nov. 3, 2014, 13 pages. |
International Search Report and Written Opinion for International App. No. PCT/US2014/061645, dated Jan. 23, 2015, 15 pages. |
International Search Report for International App. No. PCT/US13/71101, dated Mar. 31, 2014, 4 pages. |
Konstantinides, S. et al., “Pulmonary embolism hotline 2012—Recent and expected trials”, Thrombosis and Haemostasis, Jan. 9, 2013:33; 43-50. |
Konstantinides, S. et al., “Pulmonary embolism: risk assessment and management”, European Society of Cardiology; European Heart Journal, Sep. 7, 2012:33, 3014-3022. |
Kucher, N. et al., “Percutaneous Catheter Thrombectomy Device for Acute Pulmonary Embolism: In Vitro and in Vivo Testing”, Circulation, Sep. 2005:112:e28-e32. |
Kucher, N., “Catheter Interventions in Massive Pulmonary Embolism”, CardiologyRounds, Mar. 2006 vol. 10, Issue 3, 6 pages. |
Kucher, N. et al., “Management of Massive Pulmonary Embolism”, Radiology, Sep. 2005:236:3 852-858. |
Kucher, N. et al., “Randomized, Controlled Trial of Ultrasound-Assisted Catheter-Directed Thrombolysis for Acute Intermediate-Risk Pulmonary Embolism.” Circulation, 2014, 129, pp. 9 pages. |
Kuo, W. et al., “Catheter-directed Therapy for the Treatment of Massive Pulmonary Embolism: Systematic Review and Meta-analysis of Modern Techniques”, Journal of Vascular and Interventional Radiology, Nov. 2009:20:1431-1440. |
Kuo, W. et al., “Catheter-Directed Embolectomy, Fragmentation, and Thrombolysis for the Treatment of Massive Pulmonary Embolism After Failure of Systemic Thrombolysis”, American College of CHEST Physicians 2008: 134:250-254. |
Kuo, W. MD, “Endovascular Therapy for Acute Pulmonary Embolism”, Continuing Medical Education Society of Interventional Radiology (“CME”); Journal of Vascular and Interventional Radiology, Feb. 2012: 23:167-179. |
Lee, L. et al, “Massive pulmonary embolism: review of management strategies with a focus on catheter-based techniques”, Expert Rev. Cardiovasc. Ther. 8(6), 863-873 (2010). |
Liu, S. et al, “Massive Pulmonary Embolism: Treatment with the Rotarex Thrombectomy System”, Cardiovascular Interventional Radiology; 2011: 34:106-113. |
Muller-Hulsbeck, S. et al. “Mechanical Thrombectomy of Major and Massive Pulmonary Embolism with Use of the Amplatz Thrombectomy Device”, Investigative Radiology, Jun. 2001:36:6:317-322. |
Notice of Allowance for U.S. Appl. No. 13/843,742, dated Mar. 12, 2014, 13 pages. |
Notice of Allowance for U.S. Appl. No. 14/288,778, dated Dec. 23, 2014, 12 pages. |
Reekers, J. et al., “Mechanical Thrombectomy for Early Treatment of Massive Pulmonary Embolism”, CardioVascular and Interventional Radiology, 2003: 26:246-250. |
Schmitz-Rode et al., “New Mesh Basket for Percutaneous Removal of Wall-Adherent Thrombi in Dialysis Shunts,” Cardiovasc Intervent Radiol 16:7-10 1993 4 pgs. |
Schmitz-Rode et al., “Temporary Pulmonary Stent Placement as Emergency Treatment of Pulmonary Embolism,” Journal of the American College of Cardiology, vol. 48, No. 4, 2006 (5 pgs.). |
Schmitz-Rode, T. et al., “Massive Pulmonary Embolism: Percutaneous Emergency Treatment by Pigtail Rotation Catheter”, JACC Journal of the American College of Cardiology, Aug. 2000:36:2:375-380. |
Spiotta, A et al., “Evolution of thrombectomy approaches and devices for acute stroke: a technical review.” J NeuroIntervent Surg 2015, 7, pp. 7 pages. |
Svilaas, T. et al., “Thrombus Aspiration During Primary Percutaneous Coronary Intervention.” the New England Journal of Medicine, 2008, vol. 358, No. 6, 11 pages. |
Tapson, V., “Acute Pulmonary Embolism”, the New England Journal of Medicine, Mar. 6, 2008:358:2037-52. |
The Penumbra Pivotal Stroke Trial Investigators, “The Penumbra Pivotal Stroke Trial: Safety and Effectiveness of a New Generation of Mechanical Devices for Clot Removal in Intracranial Large Vessel Occlusive Disease.” Stroke, 2009, 40: p. 9 pages. |
Truong et al., “Mechanical Thrombectomy of Iliocaval Thrombosis Using a Protective Expandable Sheath,” Cardiovasc Intervent Radiol27-254-258, 2004, 5 pgs. |
Turk et al., “Adapt Fast study: a direct aspiration first pass technique for acute stroke thrombectomy.” J NeuroIntervent Surg, vol. 6, 2014, 6 pages. |
Uflacker, R., “Interventional Therapy for Pulmonary Embolism”, Journal of Vascular and Interventional Radiology, Feb. 2001: 12:147-164. |
Verma, R., MD et al. “Evaluation of a Newly Developed Percutaneous Thrombectomy Basket Device in Sheep with Central Pulmonary Embolisms”, Investigative Radiology, Oct. 2006, 41, 729-734. |
International Search Report and Written Opinion for International App. No. PCT/US2015/034987 filed Jun. 9, 2015, Applicant: Inceptus Medical, LLC, dated Sep. 17, 2015, 12 pages. |
English translation of Japanese Office Action received for JP Application No. 2016-564210, Applicant: Inceptus Medical, LLC, dated Sep. 4, 2017, 4 pages. |
Australian Exam Report received for AU Application No. 2015274704, Applicant: Inceptus Medical, LLC, dated Sep. 7, 2017, 3 pages. |
European Search Report received for EP Application No. 15805810.7, Applicant: Inceptus Medical, LLC, dated Sep. 4, 2017, 6 pages. |
International Search Report and Written Opinion for International App. No. PCT/US2016/067628 filed Dec. 19, 2016, Applicant: Inari Medical, Inc, dated Apr. 10, 2017, 11 pages. |
International Search Report and Written Opinion for International App. No. PCT/US2017/029696, Date of Filing: Apr. 26, 2017, Applicant: Inari Medical, Inc, dated Sep. 15, 2017, 19 pages. |
International Search Report and Written Opinion for International App. No. PCT/US2016/058536, Date of Filing: Oct. 24, 2016, Applicant: Inari Medical, Inc, dated Mar. 13, 2017, 14 pages. |
European First Office Action received for EP Application No. 13838945.7, Applicant: Inari Medical, Inc., dated Oct. 26, 2018, 7 pages. |
International Search Report and Written Opinion for International App. No. PCT/US2018/048786, Date of Filing: Aug. 30, 2018, Applicant: Inari Medical, Inc., dated Dec. 13, 2018, 12 pages. |
International Search Report and Written Opinion for International App. No. PCT/US2018/055780, Date of Filing: Oct. 13, 2018, Applicant: Inceptus Medical LLC., dated Jan. 22, 2019, 8 pages. |
European Search Report for European Application No. 16876941.2, Date of Filing: Dec. 19, 2016, Applicant: Inari Medical, Inc., dated Jul. 18, 2019, 7 pages. |
Extended European Search Report for European Application No. 16858462.1, Date of Filing: Oct. 24, 2016, Applicant: Inari Medical, Inc., dated Jun. 3, 2019, 10 pages. |
International Search Report and Written Opinion for International App. No. PCT/US2019/045794, Date of Filing: Aug. 8, 2019, Applicant: Inari Medical, Inc., dated Nov. 1, 2019, 17 pages. |
Partial Supplementary European Search Report for European Application No. 17864818.4, Date of Filing: May 21, 2019, Applicant: Inari Medical, Inc., dated Apr. 24, 2020, 12 pages. |
International Search Report and Written Opinion for International App. No. PCT/US2020/056067, Date of Filing: Oct. 16, 2020; Applicant: Inari Medical, Inc., dated Jan. 22, 2021, 8 pages. |
Number | Date | Country | |
---|---|---|---|
20190150959 A1 | May 2019 | US |
Number | Date | Country | |
---|---|---|---|
61949953 | Mar 2014 | US | |
61893859 | Oct 2013 | US |
Number | Date | Country | |
---|---|---|---|
Parent | 15031102 | US | |
Child | 16224193 | US | |
Parent | 14299997 | Jun 2014 | US |
Child | 14299933 | US |
Number | Date | Country | |
---|---|---|---|
Parent | 14299933 | Jun 2014 | US |
Child | 15031102 | US |