The present specification generally relates to methods and apparatuses for packaging glass articles and, more particularly, to methods and apparatuses for packaging glass articles, such as tubes for pharmaceutical packages that reduce or even eliminate glass-to-glass interactions during the packaging process.
Historically, glass has been used as the preferred material for packaging pharmaceuticals because of its hermeticity, optical clarity, and excellent chemical durability relative to other materials. Specifically, the glass used in pharmaceutical packaging must have adequate chemical durability so as not to affect the stability of the pharmaceutical compositions contained therein. Glasses having suitable chemical durability include those glass compositions within the ASTM standard ‘Type 1B’ which have a proven history of chemical durability.
However, use of glass for such applications is limited by the mechanical performance of the glass. In the pharmaceutical industry, glass breakage is a safety concern for the end user, as the broken package and/or the contents of the package may injure the end user. Further, non-catastrophic breakage (i.e., when the glass cracks but does not break) may cause the contents to lose their sterility which, in turn, may result in costly product recalls.
Specifically, handling or bundling of glass articles throughout the pharmaceutical package producing process can result in significant glass-to-glass contact, which can create scratches and defects in the glass. This mechanical damage can significantly decrease the strength of the glass pharmaceutical package resulting in an increased likelihood that cracks will develop in the glass, potentially compromising the sterility of the pharmaceutical contained in the package or causing the complete failure of the package. Reducing or even eliminating glass-to-glass contact can result in significant improvements in physical properties of the pharmaceutical packages.
Accordingly, a need exists for methods and apparatuses for packaging glass articles, such as tubes for pharmaceutical packages that reduce or even eliminate glass-to-glass interactions during the packaging process.
According to one embodiment, a method of forming bundles of glass articles is provided. The method includes transporting individual glass articles to an insert building station using a conveying system. The glass articles are individually located within article receiving slots of a layer separation insert using the conveying system. Each slot of the layer separation insert receives a single glass article forming a glass article layer of side-by-side glass articles. Multiple glass article layers that include layer separation inserts are stacked using the conveying system forming a bundle. The layer separation inserts provide a barrier between adjacent glass articles of each of the glass article layers.
In another embodiment, an apparatus that forms bundles of glass articles includes a glass article infeed station that provides glass articles to a conveying system. The conveying system transports individual glass articles to an insert building station. An insert feed station includes a plurality of layer separation inserts. The conveying system transports the plurality of layer separation inserts to the insert building station. The conveying system individually locates the glass articles within article receiving slots of the plurality of layer separation inserts. Each slot of the plurality of layer separation inserts receives a single glass article to form a glass article layer of side-by-side glass articles. A bundle building station where the conveying system stacks multiple glass article layers include layer separation inserts that form a bundle. The layer separation inserts provide a barrier between adjacent glass articles of each of the glass article layers.
In yet another embodiment, a method of forming a palletized package of bundles of glass articles is provided. The method includes building multiple glass article layers using a conveying system by individually locating the glass articles within article receiving slots of multiple layer separation inserts. The multiple glass article layers that include layer separation inserts are stacked using the conveying system forming multiple bundles. The layer separation inserts provide a barrier between adjacent glass articles of each of the glass article layers. The multiple bundles are stacked to form the palletized package.
Additional features and advantages of the glass articles and methods and processes for manufacturing the same will be set forth in the detailed description which follows, and in part will be readily apparent to those skilled in the art from that description or recognized by practicing the embodiments described herein, including the detailed description which follows, the claims, as well as the appended drawings.
It is to be understood that both the foregoing general description and the following detailed description describe various embodiments and are intended to provide an overview or framework for understanding the nature and character of the claimed subject matter. The accompanying drawings are included to provide a further understanding of the various embodiments, and are incorporated into and constitute a part of this specification. The drawings illustrate the various embodiments described herein, and together with the description serve to explain the principles and operations of the claimed subject matter.
Reference will now be made in detail to various embodiments of methods and apparatuses for packaging glass articles, such as tubes for pharmaceutical packages that reduce or even eliminate glass-to-glass interactions during the packaging process, examples of which are depicted in the figures. The glass articles may be further processed and, for example, used as glass containers suitable for use in various packaging applications including, without limitation, as pharmaceutical packages. These pharmaceutical packages may or may not contain a pharmaceutical composition. Various embodiments of the methods and apparatuses for packaging glass articles that reduce or even eliminate glass-to-glass interactions during the packaging process will be described in further detail herein with specific reference to the appended drawings.
Generally, the methods and apparatuses may utilize glass receiving inserts that are suitable for touching and supporting the glass articles. The glass receiving inserts may include individual slots that are sized and arranged to receive individual glass articles to form a layer of the glass articles. The layers of the glass articles can be stacked, one on top of the other with their glass receiving inserts which can then provide separation barriers between the layers of the glass articles and also between adjacent glass articles of the same layer. As will be described in greater detail below, the methods and apparatuses can also provide for automated packaging of the glass articles using the glass receiving inserts to reduce or even eliminate human handling of the glass articles during the packaging process.
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Layer separation inserts 42, 44 and 46 are provided between each of the glass article layers. Layer separation inserts 42 and 46 may be end layer separation inserts and layer separation insert 44 may be a middle layer separation insert. The end layer separation inserts 42 and 46 may be located near the opposite ends 26 and 28 with the middle layer separation insert 44 located therebetween. As can be seen, the layer separation inserts 42, 44 and 46 may be shorter than the length L of the glass article layers 40 and may be separated from each other along the length L providing gaps 48 between adjacent glass article layers 40. Such an arrangement can reduce material used to form the layer separation inserts 42, 44 and 46 compared to longer layer separation inserts, while still separating the glass article layers 40 from each other.
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The layer separation inserts 42, 44 and 46 may be formed of any suitable material, such as amorphous polyethylene terephthalate (APET), silicone, etc. that can contact and protect the glass articles 12, while providing the desired separation between the glass article layers 40 (
The glass articles 12 may be formed from a variety of different glass compositions. The specific composition of the glass article may be selected according to the specific application such that the glass has a desired set of physical properties.
The glass articles 12 may be formed from a glass composition which has a coefficient of thermal expansion in the range from about 25×10−7/° C. to 80×10−7/° C. For example, in some embodiments described herein, the glass articles 12 are formed from alkali aluminosilicate glass compositions which are amenable to strengthening by ion exchange. Such compositions generally include a combination of SiO2, Al2O3, at least one alkaline earth oxide, and one or more alkali oxides, such as Na2O and/or K2O. In some of these embodiments, the glass composition may be free from boron and compounds containing boron. In some other embodiments, the glass compositions may further comprise minor amounts of one or more additional oxides such as, for example, SnO2, ZrO2, ZnO, TiO2, As2O3, or the like. These components may be added as fining agents and/or to further enhance the chemical durability of the glass composition. In another embodiment, the glass surface may comprise a metal oxide coating comprising SnO2, ZrO2, ZnO, TiO2, As2O3, or the like
In one particularly exemplary embodiment, the glass articles 12 may be formed from an ion exchangeable glass composition described in pending U.S. patent application Ser. No. 13/660,894 filed Oct. 25, 2012 and entitled “Glass Compositions with Improved Chemical and Mechanical Durability” assigned to Corning, Incorporated.
However, it should be understood that the articles 12 described herein may be formed from other glass compositions including, without limitation, ion-exchangeable glass compositions and non-ion exchangeable glass compositions. For example, in some embodiments the glass container may be formed from Type 1B glass compositions such as, for example, Schott Type 1B aluminosilicate glass.
In some embodiments described herein, the glass articles 12 may be formed from a glass composition which meets the criteria for pharmaceutical glasses described by regulatory agencies such as the USP (United States Pharmacopoeia), the EP (European Pharmacopeia), and the JP (Japanese Pharmacopeia) based on their hydrolytic resistance. Per USP 660 and EP 7, borosilicate glasses meet the Type I criteria and are routinely used for parenteral packaging. Examples of borosilicate glass include, but not limited to Corning® Pyrex® 7740, 7800 and Wheaton 180, 200, and 400, Schott Duran, Schott Fiolax, KIMAX® N-51A, Gerrescheimer GX-51 Flint and others. Soda-lime glass meets the Type III criteria and is acceptable in packaging of dry powders which are subsequently dissolved to make solutions or buffers. Type III glasses are also suitable for packaging liquid formulations that prove to be insensitive to alkali. Examples of Type III soda lime glass include Wheaton 800 and 900. De-alkalized soda-lime glasses have higher levels of sodium hydroxide and calcium oxide and meet the Type II criteria. These glasses are less resistant to leaching than Type I glasses but more resistant than Type III glasses. Type II glasses can be used for products that remain below a pH of 7 for their shelf life. Examples include ammonium sulfate treated soda lime glasses. These pharmaceutical glasses have varied chemical compositions and have a coefficient of linear thermal expansion (CTE) in the range of 20-85×10−7° C.−1.
Referring to
Once the layer separation inserts 42, 44 and 46 are filled, the glass article layer 40 is provided. The glass article layer 40 may be moved using the conveying system 104 (e.g., by a robotic arm or other transport mechanism) to a bundle building station 110. At the bundle building station 110, the glass article layers 40 may be stacked by the conveying system 104, one on top of the other to form the bundle 14 (
In some embodiments, the bundle 14 may be wrapped at only certain locations. Referring briefly to
Instead or in addition to wrapping, the bundles may be packaged in a shipping container, such as a box.
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The above-described apparatuses and methods can be used to handle and package relatively large numbers of glass articles, while minimizing or even eliminating glass-to-glass contact or human contact with the glass articles. Such an arrangement can reduce potential glass article fracture sites (scratches, defects, chips, etc.), which can, in turn, improve strength of the glass articles and improve cleanliness. The apparatuses and methods may be used with or without shipping containers, such as boxes by wrapping the glass articles in a plastic film.
It will be apparent to those skilled in the art that various modifications and variations can be made to the embodiments described herein without departing from the spirit and scope of the claimed subject matter. Thus it is intended that the specification cover the modifications and variations of the various embodiments described herein provided such modification and variations come within the scope of the appended claims and their equivalents.
The present application claims priority to U.S. Provisional Application No. 62/353,939 filed Jun. 23, 2016, entitled, “Methods and Apparatuses for Packaging Glass Articles,” the entirety of which is incorporated by reference herein.
Number | Name | Date | Kind |
---|---|---|---|
1781360 | Armor | Nov 1930 | A |
2564729 | Shepard | Aug 1951 | A |
2568769 | Shepard | Sep 1951 | A |
2838173 | Emery | Jun 1958 | A |
3462582 | Cines | Aug 1969 | A |
3572005 | Allen | Mar 1971 | A |
3654745 | Smith | Apr 1972 | A |
3662512 | Zelnick | May 1972 | A |
3670866 | Olivotto | Jun 1972 | A |
3708084 | Bixler | Jan 1973 | A |
3926299 | Bradley | Dec 1975 | A |
4236855 | Wagner | Dec 1980 | A |
4250687 | Lueneberg | Feb 1981 | A |
4362454 | Kripzak | Dec 1982 | A |
4439091 | Frias | Mar 1984 | A |
4541762 | Tischler | Sep 1985 | A |
4765487 | Bliss | Aug 1988 | A |
4832183 | Lapeyre | May 1989 | A |
5000905 | Cox | Mar 1991 | A |
5180277 | Pearce | Jan 1993 | A |
5207727 | Pearce | May 1993 | A |
5769601 | Agne | Jun 1998 | A |
6558108 | Van Oord | May 2003 | B1 |
6606841 | Germunson | Aug 2003 | B1 |
7311199 | Vantilt | Dec 2007 | B2 |
7416379 | Roesch | Aug 2008 | B2 |
7766591 | Douglas | Aug 2010 | B2 |
7819621 | Veit | Oct 2010 | B2 |
8538885 | Faith et al. | Sep 2013 | B2 |
9623989 | Loevenich | Apr 2017 | B2 |
9926147 | Kuhn | Mar 2018 | B2 |
20120234714 | Arai | Sep 2012 | A1 |
20140245701 | Loevenich | Sep 2014 | A1 |
20160221736 | Hayashi et al. | Aug 2016 | A1 |
20170073173 | Kuhn et al. | Mar 2017 | A1 |
Number | Date | Country |
---|---|---|
10056422 | May 2002 | DE |
102006024072 | Nov 2007 | DE |
S49112666 | Sep 1974 | JP |
49-112666 | Oct 1974 | JP |
S5127672 | Feb 1976 | JP |
51-027672 | Mar 1976 | JP |
54-016296 | Feb 1979 | JP |
S5416296 | Feb 1979 | JP |
61-273314 | Dec 1986 | JP |
S61273314 | Dec 1986 | JP |
63-248626 | Oct 1988 | JP |
S63248626 | Oct 1988 | JP |
09-295686 | Nov 1997 | JP |
H09295686 | Nov 1997 | JP |
10-006257 | Jan 1998 | JP |
H106257 | Jan 1998 | JP |
10-194456 | Jul 1998 | JP |
H10194456 | Jul 1998 | JP |
2009-292642 | Dec 2009 | JP |
2009292642 | Dec 2009 | JP |
5127672 | Jan 2013 | JP |
2015-054723 | Mar 2015 | JP |
2014209833 | Dec 2014 | WO |
2015128452 | Sep 2015 | WO |
Entry |
---|
International Search Report & Written Opinion dated Dec. 14, 2017, for PCT/US2017/039064 filed Jun. 23, 2017. pp. 1-16. |
European Communication Pursuant to Article 94(3) EPC dated Nov. 19, 2019, for EP Patent Application No. 17739775.9. pp. 1-3. |
Japanese Patent Application No. 2018-551918 Office Action dated Sep. 17, 2021, 9 pages (4 pages of English Translation and 5 pages of Original Document); Japanese Patent Office. |
Japanese 1st Office Action & Search Report dated Jun. 2, 2021 for JP Patent Application No. 2018-551918. pp. 1-9. |
Japanese Decision of Rejection & Search Report dated Sep. 29, 2021 for JP Patent Application No. 2018-551918. pp. 1-9. |
Japanese Patent Application No. 2018-551918, Office Action dated May 21, 2021, 9 pages (4 pages of English Translation and 5 pages of Original Document), Japanese Patent Office. |
Number | Date | Country | |
---|---|---|---|
20170369194 A1 | Dec 2017 | US |
Number | Date | Country | |
---|---|---|---|
62353939 | Jun 2016 | US |