Claims
- 1. A method for improving sleep in an individual suffering from a sleep disorder or a condition wherein normal sleep is interrupted or interfered with, said method comprising administering to the individual a NO-mimetic in an amount therapeutically effective to improve sleep in the individual.
- 2. The method of claim 1 wherein the amount of NO-mimetic administered is less than an amount effective to appreciably alter systemic vascular tone.
- 3. The method of claim 2 where the amount of NO-mimetic administered is one half to one fortieth of the amount of NO-mimetic known to appreciably alter systemic vascular tone in normal circulation in a human.
- 4. The method of claim 1, wherein the NO-mimetic is administered by transdermal patch.
- 5. The method of claim 1 wherein the NO-mimetic is co-administered with an established drug for sleep disorders or a condition wherein normal sleep is interrupted or interfered with.
- 6. A method for decreasing a therapeutic dosage of an established drug for sleep disorders or a condition wherein normal sleep is interrupted or interfered with, said method comprising co-administering the established drug with a NO-mimetic.
- 7. A pharmaceutical composition comprising a NO-mimetic and an established drug for sleep disorders or a condition wherein normal sleep is interrupted or interfered with.
INTRODUCTION
[0001] This application claims the benefit of priority of U.S. provisional patent application Serial No. 60/236,727, filed Oct. 2, 2000 and U.S. provisional patent application Serial No. 60/184,087, filed Feb. 22, 2000.
Provisional Applications (2)
|
Number |
Date |
Country |
|
60184087 |
Feb 2000 |
US |
|
60236727 |
Oct 2000 |
US |
Divisions (1)
|
Number |
Date |
Country |
Parent |
09791127 |
Feb 2001 |
US |
Child |
10387269 |
Mar 2003 |
US |