Methods and compositions for increasing the efficacy of biologically-active ingredients

Information

  • Patent Application
  • 20060276339
  • Publication Number
    20060276339
  • Date Filed
    October 16, 2003
    21 years ago
  • Date Published
    December 07, 2006
    17 years ago
Abstract
The invention provides methods and compositions for modulating the sensitivity of cells to cytotoxic compounds and other active agents. In accordance with the invention, compositions are provided comprising combinations of ectophosphatase inhibitors and active agents. Active agents include antibiotics, fungicides, herbicides, insecticides, chemotherapeutic agents, and plant growth regulators. By increasing the efficacy of active agents, the invention allows use of compositions with lowered concentrations of active ingredients.
Description
BACKGROUND OF THE INVENTION

1. Field of the Invention


The present invention relates generally to the fields of cellular biology. More particularly, it concerns methods and compositions for the modulation of cellular sensitivity to biologically-active agents.


2. Description of Related Art


Transport Processes


Cells can use a phenomenon called symport to move soluble products across biological membranes. Symport is a form of coupled movement of two solutes in the same direction across a membrane by a single carrier. Examples of proton and sodium-linked symport systems are found in nearly all living systems. The energetics of the transport event depend on the relative size and electrical nature of the gradient of solutes.


Transport processes have been classified on the basis of their energy-coupling mechanisms. Currently there are four classifications: (1) Primary Active Transport which uses either a chemical, light or electrical energy source, (2) Group Translocation which uses chemical energy sources, (3) Secondary Active Transport which uses either a sodium or proton electrochemical gradient energy source, and (4) Facilitated Diffusion which does not require an energy source (Meyers, 1997). The present invention is related to transport molecules belonging to the first class of transport processes, primary active transport, and therefore, this type of transport will be discussed in further detail.


Primary active transport refers to a process whereby a “primary” source of energy is used to drive the active accumulation of a solute into or extrusion of a solute from a cell. Transport proteins include P-type ATPases and ABC-type ATPases, as well as V-type and E-type ATPases. These types of transport systems are found in both eukaryotes and prokaryotes. The bacterial ABC-type transporters, which are ATP-driven solute pumps, have eukaryotic counterparts. Additionally, many transmembrane solute transport proteins exhibit a common structural motif. The proteins in these families consist of units or domains that pass through the membrane six times, each time as an α-helix. This has led to the suggestion that many transport proteins share a common evolutionary origin, but this is not true of several distinct families of transport proteins.


Numerous structurally distinct bacterial permeases, as well as several homologous eukaryotic transport systems, share a common organization (Meyers, 1997). Two hydrophilic domains or proteins function to couple ATP hydrolysis in the cytoplasm to activate substrate uptake or efflux, and two hydrophobic domains or proteins function as the transmembrane substrate channels. These proteins or protein domains constitute what is referred to as the ABC (ATP-binding cassette) superfamily. Either the two hydrophilic domains or proteins or the two hydrophobic domains or proteins (or both) may exist either as heterodimers or homodimers. If, as in most bacterial systems, each of these constituents is a distinct protein, then either two, three, or four genes will code for them, depending on whether both are homodimers, one is a homodimer and one is a heterodimer, or both are heterodimers, respectively. The best characterized of the eukaryotic proteins included in this family are the multidrug-resistance (MDR) transporter and the cystic fibrosis related chloride ion channel of mammalian cells (cystic fibrosis transmembrane conductance regulator or CFTR) (Meyers, 1997).


Multidrug Resistance


Multidrug resistance (MDR) is a general term that refers to the phenotype of cells or microorganisms that exhibit resistance to different, chemically dissimilar, cytotoxic compounds. MDR can develop after sequential or simultaneous exposure to various drugs. MDR can also develop before exposure to many compounds to which a cell or microorganism may be found to be resistant. MDR which develops before exposure is frequently due to a genetic event which causes the altered expression and/or mutation of an ATP-binding cassette (ABC) transporter (Wadkins and Roepe, 1997). This is true for both eukaryotes and prokaryotes.


One prominent member of the ABC family, P-glycoprotein (Pgp; also known as multidrug resistance protein or MDR1), which is a plasma-membrane glycoprotein that confers a multidrug resistance (MDR) phenotype on cells, is of considerable interest because it provides one mechanism of possibly inhibiting resistance in tumor cells to chemotherapeutic agents (Senior et al., 1995). Pgp is a single polypeptide of ˜1280 amino acids with the typical ABC transporter structure profile. Studies have shown that over expression of Pgp is responsible for the ATP-dependent extrusion of a variety of compounds, including chemotherapeutic drugs, from cells (Abraham et al., 1993).


Over one-hundred ABC transporters have been identified in species ranging from Escherichia coli to humans (Higgins, 1995). For example, the bacteria Lactococcus lactis expresses an ABC transporter, LmrA, which mediates antibiotic resistance by extruding amphiphilic compounds from the inner leaflet of the cytoplasmic membrane (Van Veen et al., 1998). Furthermore, over-expression of LmrA can confer MDR in human lung fibroblasts and LmrA has similar molecular and biochemical properties to Pgp. This demonstrates that bacterial LmrA and Pgp are functionally interchangeable. Additionally, the plant Arabidopsis thaliana encodes an ATP transporter, AtPGP-1, which is a putative Pgp homolog (Dudler and Hertig, 1992). Similarly, the yeast Saccharomyces cerevisiae equivalent of Pgp, STS1 (Bissinger and Kucher, 1994) has been cloned and shown to confer multidrug resistance when over-expressed in yeast, as has the yeast Pdr5p (Kolacskowski et al., 1996). Taken together, these results suggest, that this type of multidrug resistance efflux pump is conserved from bacteria to humans.


While various theories of ABC transporter function have become popular, there is still no precise molecular-level description for the mechanism by which over-expression lowers intracellular accumulation of drugs, in particular how Pgp lowers intracellular accumulation of chemotherapeutic drugs. However, it has been shown that Pgp over-expression also changes plasma membrane electrical potential and intracellular pH which could potentially greatly affect the cellular flux of a large number of compounds to which Pgp confers resistance (Wadkins and Roepe, 1997). Also included in the ABC transporter superfamily are the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) and the Sulfonyl Urea Receptor (SUR). CFTR and SUR are expressed in the lung epithelium and the β cells of the pancreas, respectively, as well as in other tissues. CFTR functions as a low conductance ATP and cyclic AMP-dependent Clchannel that also appears to have additional important functions, such as modulation of epithelial NA+ regulation of outwardly rectified chloride channels (Wadkins and Roepe, 1997).


Mutations in the CFTR gene produce altered CFTR proteins with defects in CFTR function, leading to profound alterations in epithelial salt transport and altered mucous properties in cystic fibrosis patients that result in chronic lung infections associated with the disease. Id. SUR is triggered by sulfonyl urea drugs to depolarize pancreatic P cells that leads to Ca2+ influx, which stimulates fusion of insulin containing vesicles to the plasma membrane. Id. An ATP transporter hypothesis has been suggested for Pgp, CFTR and SUR which theorizes that these ABC transporters function as ATP transport channels (Abraham et al., 1993; Schweibert, 1995; Al-Awgati, 1995). The ATP channel hypothesis, however, has been viewed with skepticism. This is partly due to the inability to show the same results with preparations including purified and reconstituted CFTR, suggesting that the ATP conductance that was originally observed may have been mediated by another protein, not present in the purified system, that is influenced by CFTR (Wadkins and Roepe). There has been no such negative data reported with respect to the ATP charnel hypothesis for Pgp or SUR, but the controversy over CFTR has raised doubt for Pgp and SUR as well.


In support of the ATP channel hypothesis (Huang et al., 1992) have suggested that extracellular ATP leads to elevations in pH, and Weiner et al., (1986) have suggested that extracellular ATP may regulate Na/H+ exchange in Ehrlich ascites tumor cells. It has also been observed that changes in Pgp levels affects pH and plasma membrane electrical potentials which could be connected to recent observations suggesting the involvement of ATP transport in MDR.


Additionally, Abraham et al., (1993) have reported that the addition of extracellular ATP to MDR cell lines confers sensitivity to drugs abolishing MDR. The data for this effect were not presented in the article and no further explanation was given for this phenomenon. Furthermore, there have been no subsequent publications addressing or explaining this effect.


Furthermore, Ujhazy et al., (1996) have shown that ecto-5′-nucleotidase is up-regulated in certain MDR cell lines. Ecto-5′-nucleotidase is the final enzyme in the extracellular pathway for salvage of adenosine from phosphorylated purines (Zimmerman, 1992). The proposed hypothesis for the involvement of ecto-5′-nucleotidase in drug resistance considers its role in the maintenance of intracellular ATP pools through the adenosine salvage pathway (Ujhazy et al., 1996). Ecto-5′-nucleotidase specifically acts in adenosine salvage pathways, converting AMP to adenosine which is more readily taken up by the cell and utilized as a precursor for ATP production. Therefore, ecto-5′-nucleotidase may be acting in certain MDR cell lines as a mechanism by which the cell circumvents the loss of ATP (due to up-regulated transport proteins which possibly form ATP transport channels) by creating higher levels of adenosine from which the cell can produce ATP. Correspondingly, 63% of MDR cell line variants tested expressed ecto-5′-nucleotidase. These observations suggested that a salvage mechanism for extracellular nucleotides may be another way by which certain MDR cells counterbalance their ATP losses from efflux induced by the over-expression of ABC transporters involved in MMR. Consistent with this hypothesis, inhibitors of ecto-5′-nucleotidase conferred sensitivity to certain drugs in MDR cell lines which over-express the ecto-5′-nucleotidase.


It is also interesting to note that yeast, which do not have an adenosine salvage pathway (Boyum and Guidotti, 1997), do contain a PGP-like gene called STS 1 (Bissinger and Kucher, 1994). Therefore, since the adenosine salvage pathway is unlikely to be involved in yeast multidrug resistance, other mechanisms are likely to exist.


Recent reports have confirmed the existence of ATP in the extracellular matrix (ECM) of both multicellular organisms and unicellular organisms (Sedaa et al., 1990; Boyum and Guidotti, 1997), respectively. However, no such reports are available which suggest the existence of ATP in the ECM of plants before the present invention. These reports have prompted further investigations of the fate of ATP outside the cell. One of the largest gradients in biological systems is that of ATP. It is a million-fold more concentrated inside the cell than outside. Phosphatases are enzymes with the ability to hydrolyze ATP and to a lesser extent, the beta phosphate of ADP (Plesner, 1995). Extracellular phosphatases are generally referred to as ectophosphatases A type of ectophosphatase is ecto-pyrase. Given reports that show the existence of extracellular ATP, one observation regarding ectoapyrase is that it hydrolyzes the extracellular ATP. In fact, work in animal systems has shown that apyrases hydrolyze ATP in the ECM as part of the adenosine salvage pathway conjointly with ecto-5′ ectonucleotidase (Che, 1992).


What has been lacking in the art are particular methods and compositions that allow modification of cellular ATP gradients to increase the uptake of cytotoxic agents by cells. It would be particularly useful to identify methods and compositions that result in increased uptake by cells of herbicides, antibiotics, fungicides, insecticides, chemotherapeutics and other active ingredients. This may result in increased efficacy in the use of such agents, as well as allow use of lower concentrations of such agents. This may provide cost, health and environmental benefits. This may also allow effective treatment of MDR cells, such as antibiotic-resistant bacteria or chemotherapy-resistant tumor cells.


SUMMARY OF THE INVENTION

In one aspect, the invention provides a cytotoxic composition comprising an ectophosphatase inhibitor and a cytotoxic agent set forth in Table 1. In one embodiment of the invention, the cytotoxic agent is selectively cytotoxic. In other embodiments, the cytotoxic composition may be further defined as a herbicidal composition and the cytotoxic agent a herbicide, may be further defined as an insecticidal composition and the cytotoxic agent an insecticide, may be further defined as a fungicidal composition and the cytotoxic agent a fungicide and/or may be further defined as an antibiotic composition and the cytotoxic agent an antibiotic. In an antibiotic composition, the antibiotic may be from a class selected from the group consisting of Beta-lactam, Semisynthetic penicillin, Clavulanic Acid, Monobactams, Carboxypenems, Aminoglycosides, Glycopeptides, Lincomycins, Macrolides, Polyenes, Rifamycins, Tetracyclines, Semisynthetic, tetracycline and Chloramphenicol. In certain embodiments of the invention, the ectophosphatase inhibitor may be selected from the group consisting of the compounds of formulae I-XX.


In another aspect, the invention provides a plant growth regulator composition comprising an ectophosphatase inhibitor and a plant growth regulator agent set forth in Table 1. In one embodiment of the invention, the ectophosphatase inhibitor is selected from the group consisting of the compounds of formulae I-XX.


In yet another aspect, the invention provides a chemotherapeutic composition comprising an ectophosphatase inhibitory compound and a chemotherapeutic agent. In one embodiment of the invention, the chemotherapeutic agent is a chemotherapeutic agent set forth in Table 3. In further embodiments of the invention, the ectophosphatase inhibitor is selected from the group consisting of the compounds of formulae I-XX.


In still yet another aspect, the invention provides a method of killing or inhibiting the growth of a plant, comprising contacting said plant with an effective amount of a herbicidal composition provided by the invention. The method may be carried out with potentially any plant, including a monocotyledonous plant or a dicotyledonous plant.


In still yet another aspect, the invention provides a method of killing or inhibiting the growth of a tumor cell, comprising contacting said tumor cell with an effective amount of a chemotherapeutic composition of the invention. In the method, contacting may comprise administering the composition to a patient in need thereof, wherein the patient comprises the tumor cell.


In still yet another aspect, the invention provides a method of killing or inhibiting the growth of a target cell, comprising contacting said cell with a composition formulated therefore. In certain embodiments of the invention, the cell may be a fungal cell, bacterial cell, or insect cell.


In still yet another aspect, the invention provides a method of increasing the effectiveness of a cytotoxic agent, comprising admixing said cytotoxic agent with an ectophosphatase inhibitor, wherein the cytotoxic agent is selected from the group set forth in Table 1. In certain embodiments of the invention, the cytotoxic agent may be further defined as a herbicide, insecticide, fungicide, and an antibiotic. Examples of antibiotics include those from the following classes: Beta-lactam, Semisynthetic penicillin, Clavulanic Acid, Monobactams, Carboxypenems, Aminoglycosides, Glycopeptides, Lincomycins, Macrolides, Polyenes, Rifamycins, Tetracyclines, Semisynthetic, tetracycline and Chloramphenicol. In one embodiment of the invention. In one embodiment of the invention, a cytotoxic agent is a chemotherapeutic agent, for example, selected from the group set forth in Table 3.




BRIEF DESCRIPTION OF THE DRAWINGS

The following drawings form part of the present specification and are included to further demonstrate certain aspects of the present invention. The invention may be better understood by reference to one or more of these drawings in combination with the detailed description of specific embodiments presented herein.



FIGS. 1A-1C Expression of apyrase in pea and in transgenic plants (FIG. 1A) Immunoblot analysis of subcellular fractions from etiolated pea plants. (FIG. 1B) Top, the total phosphate accumulated in the shoots of three independent transgenic plants. Bottom, a corresponding Immunoblot performed on protein from ECM of wild-type and transgenic plants. (FIG. 1C) Assay of phosphatase activity in the ECM fraction of OE1 and wild-type.


FIGS. 2A-C Transport of the products of ATP hydrolysis by transgenic plants overexpressing apyrase and by wild-type plants.


FIGS. 3A-D Conference of resistance to cycloheximide (FIG. 3A, B) and nigencin (FIG. 3C, D) in wild-type and ectophosphatase deficient yeast over-expressing the Arabidopsis plant ABC transporter, AtPGP-1.


FIGS. 4A-B-3 Conference of resistance to cycloheximide (FIG. 4A) and cytokinin (FIG. 4B-1-FIG. 4B-3) in Arabidopsis plants over-expressing either the ectophosphatase, apyrase, or the ABC transporter, AtPGP-1.


FIGS. 5A-B Graph showing the growth turbidity of YMR4 yeast over-expressing the Arabidopsis plant ABC transporter AtPGP-1 grown in cycloheximide (FIG. 5A) or nigericin (FIG. 5B).



FIG. 6 Graph showing germination rate of Arabidopsis plants grown in the presence of cycloheximide which over-express either the ectophosphatase, apyrase, or the ABC transporter AtPGP-1.



FIG. 7 Graph of steady-state levels of ATP in the extracellular fluid of wildtype yeast cells grown in the presence or absence of glucose and in the presence or absence of over-expression of the Arabidopsis plant ABC transporter, AtPGP-1.



FIG. 8 Graph showing that over-expression of Arabidopsis plant ABC transporter, AtPGP-1, in yeast can double the steady-state levels of ATP in the extracellular fluid.



FIG. 9 Graph showing that a yeast mutant, YMR4, that has a deficient ectophosphatase, accumulates ATP in the extracellular fluid and the over-expression of AtPGP-1 increases the accumulation of ATP.



FIG. 10 Graph showing results of a pulse-chase experiment in either wildtype yeast cells or a yeast mutant, YMR4, which is deficient in ectophosphatase activity, in the presence and absence of over-expression of Arabidopsis plant ABC transporter, AtPGP-1, demonstrating an early differential ATP efflux of cells over-expressing AtPGP-1.



FIG. 11 Graph of ATP levels on the surface of leaves of Arabidopsis plants over-expressing AtPGP-1 (MDR 1).



FIG. 12 Effects of phosphatase inhibitor in wild-type and AtPGP-1 (MDRI) overexpressing Arabidopsis plants.



FIG. 13 Growth effects of cycloheximide and extracellular ATP on wildtype and MDR1 overexpressing S. cerevisiae yeast cells which have either never seen cycloheximide or which have been previously selected in cycloheximide.



FIG. 14 Growth effects of cycloheximide, adenosine and phosphate on wildtype and AtPGP-1 overexpressing S. cerevisiae yeast cells.




DETAILED DESCRIPTION OF THE INVENTION

The present invention provides methods and compositions for modulating the sensitivity of cells to cytotoxic compounds and other active agents. In accordance with the invention, such modulation may be carried out by modifying cellular ATP gradients, for example, by contacting a plant, animal, yeast or bacterial cell with an ectophosphatase inhibitor contemporaneously with a cytotoxic agent or other active ingredient, or combinations thereof. As used herein, the term “ectophosphatase inhibitor” refers to a compound that has the ability to specifically inhibit ectophosphatase activity. A “cytotoxic agent” is a compound capable of selectively or non-selectively killing or inhibiting the growth of a cell, including antibiotics, fungicides, herbicides, insecticides and chemotherapeutic agents.


The efficacy of one or more cytotoxic agents may be increased in accordance with the invention by reducing the ATP gradient across biological membranes, which is effectuated through the modulation of an ectophosphatase either alone or together with an ABC transporter molecule. Modulation of resistance to a cytotoxic compound as described herein is useful, for example, in increasing the sensitivity of plants to herbicides; reducing drug resistance in tumor cells for improved chemotherapy applications; and reducing resistance to antibiotics, antifungal agents, insecticides and other cytotoxic agents for the treatment of infections and disease. Provided by the invention are specific combinations of ectophosphatase inhibitors and cytotoxic compounds or other active ingredients that may be used in these applications.


In accordance with certain embodiments of the invention, the manipulation of extracellular ATP levels to alter ATP gradient across biological membranes in cells by inhibition of ectophosphatases results in diminishing or removing the ATP gradient that may otherwise prevent access of cytotoxic agents to the cell. In some instances, access may be minimized by efflux of cytotoxic agents from the cell. This efflux is likely effectuated through the “piggy-back” efflux of drug molecules with ATP, a phenomenon known as symport.


In accordance with the invention, inhibitors of ectophosphatases may be administered contemporaneously with cytotoxic agents, including herbicides, antibiotics, fungicides, insecticides and other active ingredients, as well as chemotherapeutics. By “contemporaneously,” it is meant within sufficient temporal proximity that the increased sensitivity of a cell to the relevant cytotoxic agent may be achieved in combination with contacting the cell with the agent. In certain embodiments of the invention, ectophosphatase inhibitors are used as adjuvants with cytotoxic agents, that is, are admixed with one or more cytotoxic agents or other active ingredients.


It is therefore an, object of the present invention to provide inhibitors of ectophosphatases in physiological compositions for modulating cell growth and/or survival, including, but not limited to, MDR cells. Such physiological compositions may comprise a small molecule capable of inhibiting an ectophosphatase and a physiologically acceptable carrier or diluent together with a therapeutic agent. As used herein, the term “physiologically acceptable carrier or diluent” means any and all solvents, dispersion media, antibacterial and antifungal agents, microcapsules, liposomes, cationic lipid carriers, isotonic and absorption delaying agents and the like which are not incompatible with the ectophosphatase inhibitors. The use of such media and agents for physiologically active substances is well known in the art. Supplementary active ingredients may also be incorporated into the compositions.


In certain embodiments, only an endogenous ectophosphatase is inhibited. In particular embodiments of the invention, the ectophosphatase is human apyrase. In other embodiments, the ectophosphatase is a plant, bacterial, fungal or yeast ectophosphatase.


The inhibition of ectophosphatases is useful in increasing sensitivity to cytotoxic agents and/or reduction of drug resistance in cells. In one embodiment of the invention, the inhibition of ectophosphatases results in a loss of resistance to a cytotoxic agent. In another embodiment of the invention, administration of such inhibitory molecules is in conjunction with the administration of chemotherapeutic agents in tumor cells.


Using high throughput screens, ectophosphatase inhibitors may be isolated, for example, by screening a small molecule library (e.g. a combinatorial library) for inhibitory activity to ectophosphatase (e.g. apyrase activity). Once ectophosphatase inhibitory molecules are isolated from such a screen, the inhibitors may be further tested for their ability to specifically inhibit the ATPase activity of the ectophosphatase.


Exemplary ectophosphatase inhibitory molecules for use with the current invention are preferably chemically stable and physiologically active including, but not limited to, the compounds of formulae I-XX.
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Preliminary pharmacophore studies revealed that the small molecules represented by Formulae I through XX fall into five classes of compounds (sulfanamides, guanidines, aminothiazoles, thioketones and benzamides). Most of these chemical classes are found in other physiologically-active compounds, including those having pharmaceutical and therapeutic use. For example, sulfanimides are widely used as antibiotics. Additionally, studies for the isolation of small molecules capable of reversing MDR have described molecules belonging to two of the classes of molecules of the present invention (Medina et al. 1998; Dhamant et al., 1992). The molecules described by Medina et al. have been shown to affect MDR and the mode of action of the molecules is believed to involve tubulin interactions. The thiazine derivatives described by Dhamant et al. reverse the resistance in tumor cells to vincristine.


The ectophosphatase inhibitory molecules are useful in increasing the activities of various agents by increasing the availability of the agents to cells. In certain embodiments of the invention, this may comprise reversing multidrug resistance (MDR) in an organism. In other embodiments, this may be achieved with a cell that does not exhibit MDR. Such cells may or may not comprise an up-regulated ectophosphatase


MDR reversal and/or increasing of sensitivity to a cytotoxic agent in cells may be shown by growing the cells in the presence of relevant drugs and in the presence and absence of the inhibitor. Cells which cannot grow in the presence of a drug in the presence of an ectophosphatase inhibitor, have a reversal in MDR and/or increase in sensitivity to the agent.


The ectophosphatase inhibitory compositions of the present invention are useful in reversing drug resistance in mammalian cell lines grown in the presence of a drug (e.g. a chemotherapeutic agent). Analysis of sensitivity to a chemotherapeutic composition in mammalian cells may be shown, for example, by using the fluorescent compound calcein-AM. Esterases present in cells cleave the aceto-methoxy ester (AM) from the calcein-AM and liberate calcein. Calcein is a fluorescent compound which is excitable by the 488 nm laser of a FACS Caliber flow cytometer (Becton Dickenson, Franklin Lakes, N.J.), while the uncleaved calcein-AM is not excitable. Wild type cells incubated in the presence of calcein-AM show a high level of fluorescence while MDR state cells, which efflux the calcein-AM faster than the cellular esterases can cleave it, do not show a high level of fluorescence. The mammalian cells can be tested for the reversal of MDR with ectophosphatase inhibitors by the amount of calcein fluorescence detected in the cells.


Specificity of ectophosphatase inhibitors may be tested with the screening assays described herein. Inhibitors can be tested for their ability to inhibit acid phosphatases, alkaline phosphatases, myosin phosphatases and the luciferase ATPase. The assays may be performed using techniques known in the art.


In one embodiment of the invention, the ectophosphatase is an apyrase and the ectophosphatase inhibitor is a molecule selected from among molecules represented by the Formulae I through XX. In another embodiment, the ectophosphatase is apyrase and the ectophosphatase inhibitor is a molecule selected from among molecules represented by the Formulae I through V.


In a further embodiment of the invention, the ectophosphatase is apyrase and the ectophosphatase inhibitor is a molecule represented by Formula XX. Formula XX is suramin or 8,8′[Carbonylbis[imino-3,1-phenylenecarbonylimino(4-methyl-3,1-phenylene)carbonyl imino]]bis-1,3,5-naphthalenetrisulfonic acid. Suramin has been reported as a potent non-competitive inhibitor of ectoapyrase activity associated with the plasma membrane of cholinergic nerve terminal of Torpedo mannorata electric organs (arti et al., 1996).


It is contemplated that in certain embodiments of the invention an ectophosphatase inhibitor may inhibit an ectophosphatase active on the outer membrane of an organelle of a eukaryotic cell. In this manner, contacting the cell with the ectophosphatase inhibitor may be used to decrease the ATP gradient across the organelle and thereby facilitate uptake of a biologically active agent by the organelle.


I. Formulations

Ectophosphatase inhibitor compositions, which may be acidic or basic in nature, can form a wide variety of salts with various inorganic and organic bases or acids, respectively. These salts may be physiologically acceptable for in vivo administration in mammals, including humans, as well as formulations for ex vivo applications, including agricultural use. Salts of acidic compounds are readily prepared by treating the acidic compound with an appropriate molar quantity of the chosen inorganic or organic base in an aqueous or suitable organic solvent and then evaporating the solvent to obtain the salt. Salts of basic compounds can be obtained similarly by treatment with the desired inorganic or organic acid and subsequent solvent evaporation and isolation. The skilled artisan can produce salts of ectophosphatase inhibitors using techniques known in the art.


The skilled artisan readily can determine the amount of the ectophosphatase inhibitor that is required to inhibit ectophosphatase by measuring ATPase activity in the presence and absence of varying amounts of the inhibitor. Phosphatase activity can be determined by assessing the dephosphorylation of ATP and liberation of phosphate as described herein. Additionally, parameters may be measured that are known to be associated with ectophosphatase activity to determine whether the molecule has ectophosphatase inhibitory activity. For example, ectophosphatase inhibitory activity may be measured in cells (e.g., yeast, plant, bacterial, mammalian, and tumor cell lines) by assessing the loss of resistance to drugs. Furthermore, the ectophosphatase inhibitory molecules of the present invention may be tested for specific inhibitory activity to ectophosphatases versus general phosphatases or for specific inhibitory activity for a particular ectophosphatase activity (e.g., apyrase).


The present invention also provides physiologically acceptable compositions comprising an ectophosphatase inhibitor, a cytotoxic agent or other active ingredient and a physiologically acceptable carrier or diluent. In certain embodiments of the invention, as set forth in detail below, compositions are provided comprising one or more ectophosphatase inhibitor and one or more plant growth regulator, herbicide, fungicide, insecticide, antibiotic, chemotherapeutic agent or other active compound. In a further embodiment of the invention, the ectophosphatase is selected from the compounds of formulae I-XX in the appropriate carriers, diluents or other active ingredients.


The use of physiologically acceptable carriers or diluents is well known in the art. The techniques of preparation of pharmaceutical compositions are generally well known in the art as exemplified by Remington's Pharmaceutical Sciences, 16th Ed. Mack Publishing Company, 1980, which reference is specifically incorporated herein by reference in its entirety. Formulations of the present invention may be stable under the conditions of manufacture and storage and must be preserved against contamination by microorganisms.


The physiological forms of the compositions of the invention suitable for administration include sterile aqueous solutions or dispersions and sterile powders for the extemporaneous preparation of sterile injectable solutions or dispersions. Typical carriers include a solvent or dispersion medium containing, for example, water buffered aqueous solutions (i.e., biocompatible buffers), ethanol, polyols such as glycerol, propylene glycol, polyethylene glycol, suitable mixtures thereof, surfactants, and vegetable oils. Isotonic agents such as sugars or sodium chloride may be incorporated into the subject compositions.


Pharmaceutical compositions in accordance with the invention may be used by themselves or in combination with other forms active ingredients or therapeutics. One embodiment of the invention provides formulations for parenteral administration, e.g., formulated for injection via the intravenous, intramuscular, sub-cutaneous or other such routes. Typically, such compositions can be prepared as injectables, either as liquid solutions or suspensions; solid forms suitable for using to prepare solutions or suspensions upon the addition of a liquid prior to injection also can be prepared; and the preparations also can be emulsified.


Solutions of the active compounds as free base or pharmacologically acceptable salts can be prepared in water suitably mixed with a surfactant, such as hydroxypropylcellulose. Dispersions also can be prepared in glycerol, liquid polyethylene glycols, and mixtures thereof and in oils. Under ordinary conditions of storage and use, these preparations contain a preservative to prevent the growth of microorganisms.


The pharmaceutical forms suitable for injectable use include sterile aqueous solutions or dispersions; formulations including sesame oil, peanut oil or aqueous propylene glycol; and sterile powders for the extemporaneous preparation of sterile injectable solutions or dispersions. In all cases, the form must be sterile and must be fluid to the extent that easy syringability exists. It must be stable under the conditions of manufacture and storage and must be preserved against the contaminating action of microorganisms, such as bacteria and fungi.


Carriers used also can be a solvent or dispersion medium containing, for example, water, ethanol, polyol (for example, glycerol, propylene glycol, and liquid polyethylene glycol, and the like), suitable mixtures thereof, and vegetable oils. The proper fluidity can be maintained, for example, by the use of a coating, such as lecithin, by the maintenance of the required particle size in the case of dispersion and by the use of surfactants. The prevention of the action of microorganisms can be brought about by various antibacterial and antifungal agents, for example, parabens, chlorobutanol, phenol, sorbic acid, thimerosal, and the like. In many cases, it will be preferable to include isotonic agents, for example, sugars or sodium chloride. Prolonged absorption of the injectable compositions can be brought about by the use in the compositions of agents delaying absorption, for example, aluminum monostearate and gelatin.


Sterile injectable solutions are prepared by incorporating the active compounds in the required amount in the appropriate solvent with various of the other ingredients enumerated above, as required, followed by filtered sterilization. Generally, dispersions are prepared by incorporating the various sterilized active ingredients into a sterile vehicle which contains the basic dispersion medium and the required other ingredients from those enumerated above. In the case of sterile powders for the preparation of sterile injectable solutions, the preferred methods of preparation are vacuum-drying and freeze-drying techniques which yield a powder of the active ingredient plus any additional desired ingredient from a previously sterile-filtered solution thereof.


Other modes of administration can also find use with the invention. For instance, pharmaceutical compounds may be formulated in suppositories and, in some cases, aerosol and intranasal compositions. For suppositories, the vehicle composition will include traditional binders and carriers such as polyalkylene glycols or triglycerides. Such suppositories may be formed from mixtures containing the active ingredient in the range of about 0.5% to about 10% (w/w), preferably about 1% to about 2%.


Ectophosphatase inhibitors will commonly comprise from less than 1% to about 10% w/v of a composition with an active ingredient, including about 1%, 3%, 5%, &% and about 10%. Greater or lesser amounts of the ectophosphatase inhibitors may similarly be used. Desired concentrations may readily be determined by serial preparation and assay of compositions comprising varying amounts of the selected ectophosphatase inhibitor compound. For example, in the case of herbicidal compositions, a series of test compositions comprising from about 0.1% to about 25% w/v of an ectophosphatase inhibitor together with a test herbicide may be analyzed by leaf painting and comparison of the results. Safety, efficacy, cost and other concerns may each be taken into account in selecting the desired concentrations. Alternatively, pharmaceutical compositions may be analyzed using in vitro or in vivo models.


Oral compositions may be prepared in the form of solutions, suspensions, tablets, pills, capsules, sustained release formulations, or powders. These compositions can be administered, for example, by swallowing or inhaling. Where a pharmaceutical composition is to be inhaled, the composition will preferably comprise an aerosol. Exemplary procedures for the preparation of aqueous aerosols may be found in U.S. Pat. No. 5,049,388, the disclosure of which is specifically incorporated herein by reference in its entirety. Preparation of dry aerosol preparations are described in, for example, U.S. Pat. No. 5,607,915, the disclosure of which is specifically incorporated herein by reference in its entirety.


Also useful is the administration of the compounds described herein directly in transdermal formulations with permeation enhancers such as DMSO. These compositions can similarly include any other suitable carriers, excipients or diluents. Other topical formulations can be administered to treat certain disease indications. For example, intranasal formulations may be prepared which include vehicles that neither cause irritation to the nasal mucosa nor significantly disturb ciliary function. Diluents such as water, aqueous saline or other known substances can be employed with the subject invention. The nasal formulations also may contain preservatives such as, but not limited to, chlorobutanol and benzalkonium chloride. A surfactant may be present to enhance absorption of the subject compounds by the nasal mucosa.


Upon formulation, solutions may be administered in a manner compatible with the dosage formulation and in such amount as is therapeutically effective. The formulation of choice can be accomplished using a variety of excipients including, for example, pharmaceutical grades of mannitol, lactose, starch, magnesium stearate, sodium saccharin cellulose, magnesium carbonate, and the like. Typically, pharmaceutical compositions will contain from less than 1% to about 95% of the active ingredient, preferably about 10% to about 50%. Preferably, between about 10 mg/kg patient body weight per day and about 25 mg/kg patient body weight per day will be administered to a patient, including a human patient. The frequency of administration will be determined by the care given based on patient responsiveness. Other effective dosages can be readily determined by one of ordinary skill in the art through routine trials establishing dose response curves.


Regardless of the mode of administration, suitable pharmaceutical compositions in accordance with the invention will generally include an amount of active ingredient admixed with an acceptable pharmaceutical diluent or excipient, such as a sterile aqueous solution, to give a range of final concentrations, depending on the intended use. The techniques of preparation are generally well known in the art as exemplified by Remington's Pharmaceutical Sciences, 16th Ed. Mack Publishing Company, 1980, which reference is specifically incorporated herein by reference in its entirety. It should be appreciated that endotoxin contamination should be kept minimally at a safe level, for example, less that 0.5 ng/mg protein. Moreover, for human administration, preparations should meet sterility, pyrogenicity, general safety and purity standards as required by FDA Office of Biological Standards.


The therapeutically effective doses are readily determinable using an animal model. For example, experimental animals exhibiting a target infection or other ailment are frequently used to optimize appropriate therapeutic doses prior to translating to a clinical environment. Such models are known to be very reliable in predicting effective therapies. In certain embodiments, it may be desirable to provide a continuous supply of therapeutic compositions to the patient. For intravenous or intraarterial routes, this is accomplished by drip system. For topical applications, repeated application would be employed. For various approaches, delayed release formulations could be used that provided limited but constant amounts of the therapeutic agent over and extended period of time. For internal application, continuous perfusion of the region of interest may be preferred. This could be accomplished by catheterization, post-operatively in some cases, followed by continuous administration of the therapeutic agent. The time period for perfusion would be selected by the clinician for the particular patient and situation, but times could range from about 1-2 hours, to 2-6 hours, to about 6-10 hours, to about 10-24 hours, to about 1-2 days, to about 1-2 weeks or longer. Generally, the dose of the therapeutic composition via continuous perfusion will be equivalent to that given by single or multiple injections, adjusted for the period of time over which the injections are administered. It is believed that higher doses may be achieved via perfusion, however.


Therapeutic kits comprising the compositions described herein are also provided by the invention. Such kits will generally contain, in suitable container means, a pharmaceutically or agriculturally acceptable formulation of the active ingredient. The kits also may contain other pharmaceutically acceptable formulations, such as an antiinfective agent, including an insecticide, antifungal or antibacterial, as well as a herbicide.


The kits may have a single container means that contains the active ingredient, with or without any additional components, or they may have distinct container means for each desired agent. When the components of the kit are provided in one or more liquid solutions, the liquid solution is an aqueous solution, with a sterile aqueous solution being particularly preferred. However, the components of the kit may be provided as dried powder(s). When reagents or components are provided as a dry powder, the powder can be reconstituted by the addition of a suitable solvent. It is envisioned that the solvent also may be provided in another container means. The container means of the kit will generally include at least one vial, test tube, flask, bottle, syringe or other container means, into which the active compound, and any other desired agent, may be placed and, preferably, suitably aliquoted. Where additional components are included, the kit will also generally contain a second vial or other container into which these are placed, enabling the administration of separated designed doses. The kits also may comprise a second/third container means for containing a sterile, pharmaceutically acceptable buffer or other diluent.


The kits also may contain a means by which to administer the compositions to an animal or patient, e.g., one or more needles or syringes, or even an eye dropper, pipette, or other such like apparatus, from which the formulation may be injected into the animal or applied to a afflicted area of the body. The kits of the present invention will also typically include a means for containing the vials, or such like, and other component, in close confinement for commercial sale, such as, e.g., injection or blow-molded plastic containers into which the desired vials and other apparatus are placed and retained.


The invention also provides compositions formulated for agricultural use. Examples of such formulations include herbicidal, fungicidal and plant growth regulator compositions. Specific formulations for plant application are known to those of skill in the art and are described, for example, in U.S. Pat. No. 6,242,382, the disclosure of which is specifically incorporated herein by reference in its entirety.


Examples of ingredients that may be included in a composition of the invention formulated for application to plants include surfactants, solid or liquid carriers, solvents and binders. Examples of suitable surfactants that may be used for application to plants include the alkali metal, alkaline earth metal or ammonium salts of aromatic sulfonic acids, e.g., ligno-, phenol-, naphthalene- and dibutylnaphthalenesulfonic acid, and of fatty acids of arylsulfonates, of alkyl ethers, of lauryl ethers, of fatty alcohol sulfates and of fatty alcohol glycol ether sulfates, condensates of sulfonated naphthalene and its derivatives with formaldehyde, condensates of naphthalene or of the naphthalenesulfonic acids with phenol and formaldehyde, condensates of phenol or phenolsulfonic acid with formaldehyde, condensates of phenol with formaldehyde and sodium sulfite, polyoxyethylene octylphenyl ether, ethoxylated isooctyl-, octyl- or nonylphenol, tributylphenyl polyglycol ether, alkylaryl polyether alcohols, isotridecyl alcohol, ethoxylated castor oil, ethoxylated triarylphenols, salts of phosphated triarylphenolethoxylates, lauryl alcohol polyglycol ether acetate, sorbitol esters, lignin-sulfite waste liquors or methylcellulose, or mixtures of these. Common practice in the case of surfactant use is to include about 0.5 to 25% by weight, based on the total weight of the solid mixture.


Compositions for application to plants may be solid or liquid. Where solid compositions are used, it may be desired to include one or more carrier materials with the active compound. Examples of carriers include mineral earths such as silicas, silica gels, silicates, talc, kaolin, attaclay, limestone, chalk, loess, clay, dolomite, diatomaceous earth, calcium sulfate, magnesium sulfate, magnesium oxide, ground synthetic materials, fertilizers such as ammonium sulfate, ammonium phosphate, ammonium nitrate, thiourea and urea, products of vegetable origin such as cereal meals, tree bark meal, wood meal and nutshell meal, cellulose powders, attapulgites, montmorillonites, mica, vermiculites, synthetic silicas and synthetic calcium silicates, or mixtures of these.


For liquid solutions, water-soluble compounds or salts may be included, such as sodium sulfate, potassium sulfate, sodium chloride, potassium chloride, sodium acetate, ammonium hydrogen sulfate, ammonium chloride, ammonium acetate, ammonium formate, ammonium oxalate, ammonium carbonate, ammonium hydrogen carbonate, ammonium thiosulfate, ammonium hydrogen diphosphate, ammonium dihydrogen monophosphate, ammonium sodium hydrogen phosphate, ammonium thiocyanate, ammonium sulfamate or ammonium carbamate.


Other exemplary components in compositions of the invention include binders such as polyvinylpyrrolidone, polyvinyl alcohol, partially hydrolyzed polyvinyl acetate, carboxymethylcellulose, starch, vinylpyrrolidone/vinyl acetate copolymers and polyvinyl acetate, or mixtures of these; lubricants such as magnesium stearate, sodium stearate, talc or polyethylene glycol, or mixtures of these; antifoams such as silicone emulsions, long-chain alcohols, phosphoric esters, acetylene diols, fatty acids or organofluorine compounds, and complexing agents such as: salts of ethylenediaminetetraacetic acid (EDTA), salts of trinitrilotriacetic acid or salts of polyphosphoric acids, or mixtures of these.


In certain embodiments of the invention, compositions are provided with herbicidal activity which comprise one or more ectophosphatase inhibitor(s) and a herbicide selected from the group consisting of pendimethalin, dicamba, 2,4-D, glufosinate, bentazon, trifluralin, oryzalin, S-metolachlor, nicosulfuron, MSMA, Epic™ and Balance™. In one embodiment of the invention, the ectophosphatase inhibitor is selected from the group of the compounds of formulae I-XX. In certain other embodiments of the invention, compositions with fungicidal activity are provided which comprise one or more ectophosphatase inhibitor(s) in combination with metalaxyl, tebuconazole, propiconazole, chlorothalonil and/or fluconazole.


Non-limiting examples of combinations of cytotoxic agents and ectophosphatase inhibitors for use in accordance with the invention include: fluconazole with compound(s) of formula II, IX, XIV, XVI, XV, X and/or XII; formula I and/or II with pendimethalin, dicamba, 2,4-D, bentazon, trifluralin, flufenacet/isoxaflutole or isoxaflutole; glufosinate with formula II; oryzalin with formula I; nicosulflron with formula II; MSMA with formula XVIII; S-metolachlor with formula VI and/or X; metribuzin with formula I, II and/or X; diuron with formula VI; metalaxyl with formula X; chlorothalonil with formula II, X, IX, XI, XVI; propiconazole with formula I, X, XIV and/or XVI; mancozeb with formula I, VI and/or X; captan with formula XIV and/or XVI; tebuconazole with formula I and/or X; imidacloprid with formula II, X, XVIII, XVI and/or XV; and fertilizers such as Nitrogen, Phosphate, Potash—12:12:12 with formula I and/or II.


Also envisioned for use with the invention are compositions comprising combinations of ectophosphatase inhibitors and cytotoxic agents or other active ingredients, including a herbicide, insecticide, antibiotic, fungicide, plant growth regulator and/or hormone. Such combinations may provide enhanced activity of the active ingredient relative to the use of a single ectophosphatase inhibitor. Non-limiting examples of such combinations of ectophosphatase inhibitors include combinations of two, three, four or more ectophosphatase inhibitors selected from formulas I, II, VI, X, XV, XIV, XVI, XVI, XV, and XVIII. Included for illustrative purposes are the following combinations: I and II; I, II and X; XIV and XVI; XVIII and XVI; XVI, XVI and XV; VI and X; II and X; and I and XVIII.


Specifically contemplated by the inventors are compositions comprising an ectophosphatase inhibitor and an active ingredient set forth in Table 1.

TABLE 1Cytotoxic agents and other active ingredientsU.S. EPA PCCA ChemChemical NameCAS NumberCodeCodeUse TypeChemical ClassBis(2-ethylhexyl) phthalate117-81-73E+05NA 11N/AAlkyl PhthalateButyl benzyl phthalate85-68-7NA 1413080N/AAlkyl PhthalateChlorthal-dimethyl1861-32-178701179HerbicideAlkyl PhthalateDi-n-octyl phthalate117-84-0NA 303223N/AAlkyl PhthalateDibutyl phthalate84-74-228001199InsectAlkyl PhthalateRepellentDiethyl phthalate84-66-21E+053326N/AAlkyl PhthalateDiisodecyl phthalateNA 1037NA 1322513N/AAlkyl PhthalateDimethyl phthalate131-11-328002232InsectAlkyl PhthalateRepellentDioctyl terephthalateNA 724NA 1332528N/AAlkyl PhthalateDiphenyl phthalate84-62-817001NA 147N/AAlkyl PhthalateIsooctyl phthalate27554-26-3NA 4832262N/AAlkyl Phthalaten-Butyl phthalate84-74-2280013081InsecticideAlkyl PhthalatePoly glyceryl phthalate ester ofNA 327NA 6083331Adjuvant,Alkyl Phthalatecoconut oil fatty acidSoap/Surfactant1,3-Dimethyl-1,1,3,3-22232-20-834601NA 303N/ABis-Carbamatedisiloxanetetrol-1,3-bis(dimethylthiocarbamate)2,3(and 3,4)-Dichlorobenzyl62046-37-13E+05NA 136InsecticideN-Methyl Carbamatemethylcarbamates2,4-Dimethyl-1,3-dithiolane-2-26419-73-84E+05NA 143InsecticideN-Methyl Carbamatecarboxaldehyde O-(methylcarbamoyl)oxime2-(4,5-Dimethyl-1,3-dioxolan-########4E+05NA 145InsecticideN-Methyl Carbamate2-yl)phenyl-N-methylcarbamate2-chloro-4,5-xylyl N-hydroxy-14357-82-52E+05NA 117InsecticideN-Methyl CarbamateN-methylcarbamate2-cyclopentylphenyl3282-00-63E+05NA 132InsecticideN-Methyl Carbamatemethylcarbamate2-Hydroxyphenyl10309-97-42E+05NA 118InsecticideN-Methyl Carbamatemethylcarbamate3,4-Dichlorobenzyl2328-31-63E+05NA 136InsecticideN-Methyl Carbamatemethylcarbamate3,5-Diisopropylphenyl330-64-34E+05NA 142InsecticideN-Methyl Carbamatemethylcarbamate3-hydroxycarbofuran16655-82-62E+054074BreakdownN-Methyl Carbamateproduct3-iodo-2-propynyl butyl55406-53-61E+051938Fungicide,Other CarbamatecarbamateWoodPreservative3-ketocarbofuran16709-30-1NA 176NA 164BreakdownN-Methyl Carbamateproduct4-17702-57-74E+05NA 142InsecticideN-Methyl Carbamate(((Dimethylamino)methylene)amino)-m-tolylmethylcarbamate4-(Methylamino)-3,5-xylyl10389-50-12E+05NA 118InsecticideN-Methyl Carbamatemethylcarbamate4-(Methylformamido)-3,5-10233-94-02E+05NA 118InsecticideN-Methyl Carbamatexylyl methylcarbamate4-(Methylthio)-m-tolyl3566-00-56E+05NA 157InsecticideN-Methyl Carbamatemethylcarbamate4-Amino-3,5-xylyl831-76-52E+05NA 117InsecticideN-Methyl Carbamatemethylcarbamate5,6,7,8-Tetrahydro-1-naphthyl1136-84-14E+05NA 148InsecticideN-Methyl Carbamatemethylcarbamate6-(and 2)-chloro-3,4-xylyl8063-85-238701NA 322InsecticideN-Methyl Carbamatemethylcarbamate6-Methyl-2-propyl-4-2532-49-26E+05NA 157N/AOther Carbamatepyrimidinyl dimethylcarbamateAlanycarb83130-01-2NA 175NA 47InsecticideOther CarbamateAldicarb116-06-398301575Insecticide,N-Methyl CarbamateNematicideAldicarb sulfoxide1646-87-31E+052361BreakdownN-Methyl CarbamateproductAldoxycarb1646-88-41E+052265BreakdownN-Methyl CarbamateproductAllyxycarb6392-46-73E+05NA 133InsecticideN-Methyl CarbamateAminocarb2032-59-9444012435InsecticideN-Methyl CarbamateAsulam3337-71-11E+055076HerbicideOther CarbamateAsulam, sodium salt2302-17-21E+051746HerbicideOther CarbamateBendiocarb22781-23-31E+051924InsecticideN-Methyl CarbamateBenfuracarb82560-54-11E+05NA 48InsecticideOther CarbamateBufencarb2282-34-05930291InsecticideN-Methyl CarbamateBufencarb8065-36-959303NA 485InsecticideN-Methyl CarbamateBufencarb, component of (with672-04-859301NA 484InsecticideN-Methyl Carbamate059302)Butacarb2655-19-83E+05NA 135InsecticideN-Methyl CarbamateButocarboxim34681-10-2NA 175NA 49InsecticideN-Methyl CarbamateButoxycarboxim34681-23-71E+052201InsecticideN-Methyl CarbamateButylate2008-41-541405565HerbicideThiocarbamateCalcium5895-18-114501NA 139MicrobiocideDithiocarbamateethylenebis(dithiocarbamate)Carbanolate671-04-52E+05NA 124InsecticideN-Methyl CarbamateCarbaryl63-25-256801105Insecticide,N-Methyl CarbamatePlant GrowthRegulator,NematicideCarbofuran1563-66-290601106Insecticide,N-Methyl CarbamateNematicideCarbosulfan55285-14-8906022182InsecticideN-Methyl CarbamateChlorbufam1967-16-46E+05NA 157HerbicideOther CarbamateChlorprocarb23121-99-533E+05NA 136HerbicideOther CarbamateChlorpropham101-21-318301141Herbicide,Other CarbamatePlant GrowthRegulatorCloethocarb51487-69-51E+05NA 100Insecticide,N-Methyl CarbamateMolluscicideCufraneb11096-18-7NA 181NA 180FungicideDithiocarbamateCycloate1134-23-241301516HerbicideThiocarbamateDesmedipham13684-56-51E+051748HerbicideBis-CarbamateDiammonium########14502NA 140MicrobiocideDithiocarbamateethylenebis(dithiocarbamate)Dichlormate1966-58-13E+05690HerbicideN-Methyl CarbamateDiethofencarb87130-20-9NA 184NA 183FungicideOther CarbamateDimepiperate61432-55-1NA 186NA 185HerbicideThiocarbamateDimetan122-15-61E+05NA 112InsecticideOther CarbamateDimethyl (4-methyl-1,3-51543-98-71E+05NA 888FungicideBis-Carbamatephenylenebis(iminocarbonyl-1H-benzimidazole-1,2-diyl))biscarbamateDimetilan644-64-490101NA 844InsecticideOther CarbamateDioxacarb6988-21-24E+054067InsecticideN-Methyl CarbamateEPTC759-94-441401264HerbicideThiocarbamateEsprocarb85785-20-2NA 203NA 202HerbicideThiocarbamateEthiofencarb29973-13-51E+05NA 50InsecticideN-Methyl CarbamateEthiolate2941-55-11E+051793HerbicideThiocarbamateFenethacarb30087-47-93E+05NA 141InsecticideN-Methyl CarbamateFenobucarb3766-81-2NA 176NA 51InsecticideN-Methyl CarbamateFenothiocarb62850-32-2NA 188NA 187InsecticideThiocarbamateFenoxycarb79127-80-31E+052283Insecticide,Other CarbamateInsect GrowthRegulatorFenoxycarb72490-01-8NA 228NA 228Insecticide,Other CarbamateInsect GrowthRegulatorFerbam14484-64-134801288FungicideDithiocarbamateFerric nitroso dimethyl83542-83-05E+05NA 149MicrobiocideDithiocarbamatedithiocarbamateFormetanate22259-30-95E+05NA 150InsecticideN-Methyl CarbamateFormetanate hydrochloride23422-53-997301111InsecticideN-Methyl CarbamateFurathiocarb65907-30-4NA 176NA 52InsecticideThiocarbamateIsolan119-38-05E+05NA 155InsecticideOther CarbamateIsopolinate3134-70-1NA 232NA 232HerbicideThiocarbamateIsoprocarb2631-40-55E+05NA 53InsecticideN-Methyl CarbamateKarbutilate4849-32-597401691HerbicideOther Carbamatem-Cumenyl methylcarbamate64-00-647801NA 414InsecticideN-Methyl CarbamateMancopper53988-93-5NA 181NA 180FungicideDithiocarbamateMancozeb########14504211FungicideDithiocarbamate,Inorganic-ZincManeb12427-38-214505369FungicideDithiocarbamateManeb and nickel sulfate8005-46-76E+05NA 158FungicideDithiocarbamate,hexahydrate (014505 + 050505)Inorganic-NickelManganous15339-36-334802NA 304FungicideDithiocarbamatedimethyldithiocarbamateMecarbinizid27386-64-76E+05NA 157N/AOther CarbamateMercuric dimethyl15415-64-234808709MicrobiocideInorganic-Mercury,dithiocarbamateHeavy metal,DithiocarbamateMetam sodium, dihydrate137-42-839003NA 163Fumigant,DithiocarbamateFungicide,Microbiocide,Algaecide,NematicideMetam-sodium6734-80-139003616Fumigant,DithiocarbamateHerbicide,Fungicide,Microbiocide,Algaecide,NematicideMethasulfocarb66952-49-6NA 202NA 201Fungicide,ThiocarbamatePlant GrowthRegulatorMethiobencarb18357-78-3NA 232NA 232HerbicideThiocarbamateMethiocarb2032-65-71E+05375Insecticide,N-Methyl CarbamateMolluscicideMethiocarb sulfone2179-25-12E+054077BreakdownN-Methyl CarbamateproductMethiocarb sulfoxide########2E+054078BreakdownN-Methyl CarbamateproductMethomyl16752-77-590301383Insecticide,N-Methyl CarbamateBreakdownproductMetiram9006-42-214601493FungicideDithiocarbamate,Inorganic-ZincMetolcarb1129-41-5NA 202NA 201InsecticideN-Methyl CarbamateMexacarbate315-18-444201623InsecticideN-Methyl CarbamateMobam1079-33-090401NA 848InsecticideN-Methyl CarbamateMolinate2212-67-141402449HerbicideThiocarbamateMolinate sulfoxideNA 1052NA 1564080BreakdownThiocarbamateproductMorpholinomethyl31848-11-06E+05NA 158MicrobiocideDithiocarbamatedimethyldithiocarbamateNabam142-59-614503417Fungicide,DithiocarbamateHerbicideNitrilacarb29672-19-32E+05NA 129InsecticideOther Carbamateo-(2-Propynyloxy)phenyl3279-46-73E+05NA 138InsecticideN-Methyl CarbamatemethylcarbamateOrbencarb34622-58-7NA 189NA 188HerbicideThiocarbamateOxamyl23135-22-01E+051910Insecticide,N-Methyl CarbamateNematicidePebulate1114-71-241403590HerbicideThiocarbamatePhenisopham57375-63-0NA 209NA 208HerbicideBis-CarbamatePhenmedipham13684-63-498701675HerbicideBis-CarbamatePhenmedipham-ethyl13684-44-14E+05NA 149HerbicideBis-CarbamatePhenylmercuric32407-99-166008NA 555Microbiocide,Organomercury,dimethyldithiocarbamateFungicideDithiocarbamate,Heavy metalPirimicarb23103-98-21E+051875InsecticideN-Methyl CarbamatePirimicarb sulfoneNA 1050NA 1554090BreakdownN-Methyl CarbamateproductPirimicarb sulfoxideNA 1049NA 1554091BreakdownN-Methyl CarbamateproductPotassium ammonium22221-14-314507NA 141MicrobiocideDithiocarbamateethylenebis(dithiocarbamate)Potassium asulam14089-43-11E+05NA 893HerbicideOther CarbamatePotassium dimethyl dithio128-03-0348031934MicrobiocideDithiocarbamatecarbamatePotassium N-hydroxymethyl-51026-28-91E+051824N/ADithiocarbamateN-methyldithio carbamatePotassium N-methyldithio137-41-739002970Fumigant,DithiocarbamatecarbamateFungicide,Microbiocide,Algaecide,NematicidePromacyl34264-24-9NA 209NA 209InsecticideN-Methyl CarbamatePromecarb2631-37-03E+054092InsecticideN-Methyl CarbamatePropamocarb24579-73-51E+052147FungicideOther CarbamatePropamocarb hydrochloride25606-41-11E+054022FungicideOther CarbamatePropham122-42-947601339Herbicide,Other CarbamatePlant GrowthRegulatorPropineb12071-83-95E+05NA 155Fungicide,Dithiocarbamate,MicrobiocideInorganic-ZincPropoxur114-26-14780262InsecticideN-Methyl CarbamatePropoxur, other relatedNA 1073NA 16190062InsecticideN-Methyl CarbamateProsulfocarb52888-80-9NA 185NA 184HerbicideThiocarbamateProthiocarb19622-08-3NA 183NA 182FungicideThiocarbamateProthiocarb hydrochloride19622-19-6NA 200NA 199FungicideThiocarbamatePyributicarb88678-67-5NA 229NA 229HerbicideThiocarbamatePyrolan87-47-86E+05NA 157InsecticideOther CarbamateS-tert-Butyl2212-63-72E+05NA 128HerbicideThiocarbamatedipropylthiocarbamateSodium dimethyl dithio128-04-134804548FungicideDithiocarbamatecarbamateSulfallate95-06-739001115HerbicideDithiocarbamateSwep1918-18-9846014098N/AOther CarbamateTerbutol########3880151HerbicideN-Methyl CarbamateTert-butyl dimethyl trithio3304-97-0348071383RodentDithiocarbamateperoxycarbamateRepellentTert-NA 1130NA 16691383N/ADithiocarbamatebutyldimethyltrithioperoxycarbamate,other relatedThiobencarb28249-77-61E+051933HerbicideThiocarbamateThiobencarb sulfoxideNA 1042NA 1392937BreakdownThiocarbamateproductThiocarboxime25171-63-56E+05NA 156N/AN-Methyl CarbamateThiodicarb59669-26-01E+052202Molluscicide,ThiocarbamateInsecticideThiofanox39196-18-41E+052938InsecticideN-Methyl CarbamateThiram137-26-879801589FungicideDithiocarbamateThiram and NAD and IBA and75497-92-656011NA 463Fungicide,Dithiocarbamate2-methyl-1-Plant Growthnaphthaleneacetamide and 2-Regulatormethyl-1-naphthaleneaceticacidTiocarbazil36756-79-31E+05NA 911HerbicideThiocarbamateTriallate2303-17-57880249HerbicideThiocarbamateTricopper dichloride7076-63-35E+05NA 152MicrobiocideDithiocarbamate,dimethyldithiocarbamateInorganic-CopperTrimethacarb12407-86-21E+052962Insecticide,N-Methyl CarbamateMolluscicide,Dog and CatRepellentTrimethacarb, (2,3,5)-2655-15-41E+05NA 882Insecticide,N-Methyl Carbamatecomponent ofMolluscicideTrimethacarb, (3,4,5)-2686-99-91E+05NA 881Insecticide,N-Methyl Carbamatecomponent ofMolluscicideVernolate1929-77-7414041987HerbicideThiocarbamateXMC2655-14-3NA 176NA 54InsecticideN-Methyl CarbamateXylylcarb########NA 176NA 55InsecticideN-Methyl CarbamateZineb12122-67-714506627FungicideDithiocarbamate,Inorganic-ZincZineb-ethylene thiuramNA 1465NA 217NA 216FungicideDithiocarbamate,disulfide adductInorganic-ZincZiram137-30-434805629Fungicide,Dithiocarbamate,Microbiocide,Inorganic-ZincDog and CatRepellentZiram, cyclohexylamine16509-79-8348061328Dog and CatDithiocarbamate,complexRepellent,Inorganic-ZincFungicideAcetamiprid135410-20-799050NA 864InsecticideChloro-nicotinylImidacloprid105827-78-9#####3849InsecticideChloro-nicotinylImidacloprid138261-41-3#####NA 111InsecticideChloro-nicotinylThiacloprid111988-49-9NA 201NA 201InsecticideChloro-nicotinylHalofenozide112226-61-6#####5019InsecticideDiacylhydrazineMethoxyfenozide161050-58-4#####NA 983InsecticideDiacylhydrazineTebufenozide112410-23-8#####3957InsecticideDiacylhydrazineBacillus thuringiensis Cry1FNA 14866481NA 220InsecticideGE Cropprotein and the genetic materialnecessary for its production(plasmid insert PHI8999) incorn plaBacillus thuringiensis Cry1AbNA 14876430NA 220InsecticideGE CropDelta-Endotoxin and theGenetic Material Necessary forIts Production in Corn [MON810]Bacillus thuringiensis delta68038-71-1NA 1603954InsecticideGE Cropendotoxin produced in cornBacillus thuringiensis subsp.NA 12266463NA 170InsecticideGE CropKurstaki CryIA (c) delta-endotoxin and the geneticmaterial necessary for itsproduction in cornBacillus thuringiensis subsp.68038-71-164445048InsecticideGE CropKurstaki, delta-endotoxin asproduced in corn by an HD-1gene, and its controllingsequences andBacillus thuringiensis subsp.NA 12336466NA 171InsecticideGE CropTolworthi Cry9C protein andthe genetic material necessaryfor its production (pRVA9909)in corn pBacillus thuringiensisNA 12376432NA 171InsecticideGE Cropsubspecies Tenebrionis deltaendotoxin as produced inpotato by Cry IIIA gene and itscontrolling sequencBacillus thuringiensis var.NA 148064023554InsecticideGE CropKurstaki protein in cottonseedBacillus thuringiensis, subsp.68038-71-164613986InsecticideGE CropKurstaki, strain HD-1, delta-endotoxin as produced in cornby a Cry 1A(b) gene and itscontrollingHD-1 Protein as encoded byNA 12736408NA 173InsecticideGE CropBacillus thuringiensis subsp.kurstaki gene and produced incornPlant pesticide BacillusNA 12856458NA 174InsecticideGE Cropthuringiensis Cry1A(b) delta-endotoxin and the geneticmaterial necessary for itsproduction (plasmid VPotato leafroll virus (PLRV)NA 12956469NA 175FungicideGE Cropreplicase protein as produced inpotato plants1,1,1-trichloroethane71-55-681201138SolventHalogenated organic1,1,2-trichloro-1,2,2-trifluoro-76-13-1NA 9722960SolventHalogenated organicethane1,1,2-trichloroethane79-00-5812031425SolventHalogenated organic1,2,3,4-Tetrachlorobenzene634-66-261101NA 494N/AHalogenated organic1,2,4-trichlorobenzene120-82-181101600N/AHalogenated organic1,2-dichloropropane78-87-5290022501Fumigant,Halogenated organicNematicide1,2-Dichloropropane mixt. with########29004NA 215Fumigant,Halogenated organic1,3-dichloropropene andNematicidemethyl isothiocyanate1,2-dichloropropane, 1,3-NA 102229002185Fumigant,Halogenated organicdichloropropene and related C3Nematicidecompounds1,3-Dichloro-1-propene, mixt.8003-19-829003NA 214Fumigant,Halogenated organicwith 1,2-dichloropropaneNematicide1,3-dichloropropene542-75-629001573Fumigant,Halogenated organicNematicide1-chloro-1,1-difluoro ethane75-68-3NA 4233103SolventHalogenated organic1-chlorobutane109-69-3NA 4251151SolventHalogenated organic3-chloro-2-methyl propene563-47-3NA 4222463N/AHalogenated organicBis(2,2-dichloroethyl)ether1191-17-929502NA 217N/AHalogenated organicBromoethane74-96-4NA 1312427N/AHalogenated organicCarbon tetrachloride56-23-516501109Solvent,Halogenated organicFumigantCarbon tetrachloride with EDB53908-27-316503NA 146Fumigant,Halogenated organic& EDCNematicideCarbon tetrachloride with EDC########16502NA 145Fumigant,Halogenated organicNematicideCarbon tetrafluoride75-73-0NA 1133099PropellantHalogenated organicChloro difluoro methane75-45-6153104Propellant,Halogenated organicFumigant,InsecticideChlorodibromomethane124-48-1NA 4262462N/AHalogenated organicChloroform67-66-320701133Solvent,Halogenated organicFumigantDBCP96-12-811301183Fumigant,Halogenated organicNematicideDBCP, other relatedNA 1079NA 16190183Fumigant,Halogenated organicNematicideDichloroethylene, 1,1-75-35-46E+05NA 13ImpurityHalogenated organicDichlorofluoromethane75-43-4NA 3481815PropellantHalogenated organicDifluoro diphenyl475-26-332001NA 293N/AHalogenated organictrichloroethaneEthane, 1,1,1,2-tetrafluoro-811-97-21E+05NA 873N/AHalogenated organicEthyl chloride75-00-3NA 1143198N/AHalogenated organicEthylene chlorobromide107-04-0420012557N/AHalogenated organicEthylene dibromide106-93-442002271Fumigant,Halogenated organicNematicideEthylene dichloride107-06-242003274Fumigant,Halogenated organicInsecticideFreon 1175-69-4131460Propellant,Halogenated organicFumigant,InsecticideFreon 1275-71-8141459Propellant,Halogenated organicFumigant,InsecticideHalazone80-13-777201316N/AHalogenated organicHexachloroacetone116-16-543701320HerbicideHalogenated organicHexachloroacetone, otherNA 1090NA 16290320HerbicideHalogenated organicrelatedHexachloroethane67-72-145201NA 22N/AHalogenated organicHydrofluorocarbon 152ANA 617NA 1122599PropellantHalogenated organicMethyl bromide74-83-953201385Fumigant,Halogenated organicInsecticide,Herbicide,NematicideMethyl chloride74-87-3532022677N/AHalogenated organicMethyl iodide74-88-4NA 177NA 165Fumigant,Halogenated organicNematicideMethylene chloride75-09-242004388Solvent, DogHalogenated organicand CatRepellentOrtho-dichlorobenzene95-50-159401578InsecticideHalogenated organicOrtho-dichlorobenzene, otherNA 1116NA 16590683InsecticideHalogenated organicrelatedPara-dichlorobenzene106-46-761501455Insecticide,Halogenated organicInsectRepellent,Rodenticide,FungicidePentachloroethane76-01-76E+05NA 159N/AHalogenated organicPropargyl bromide106-96-768701NA 608Fumigant,Halogenated organicNematicideTetrachloroethane79-34-5786013559Solvent,Halogenated organicFumigantTetrachloroethylene127-18-4785011174SolventHalogenated organicTetraiodo ethylene513-92-846908582N/AHalogenated organictrans-1,3-Dichloropropene10061-02-6NA 227NA 227FumigantHalogenated organicTrichloro ethylene79-01-681202595N/AHalogenated organicTrichlorobenzene87-61-6NA 9711619N/AHalogenated organicTrichlorofluoromethane75-69-4133482Propellant,Halogenated organicFumigant,InsecticideTrichloromethane67-66-3207011758Solvent,Halogenated organicFumigant2,3(and 3,4)-Dichlorobenzyl62046-37-1#####NA 136InsecticideN-Methyl Carbamatemethylcarbamates2,4-Dimethyl-1,3-dithiolane-2-26419-73-8#####NA 143InsecticideN-Methyl Carbamatecarboxaldehyde O-(methylcarbamoyl)oxime2-(4,5-Dimethyl-1,3-dioxolan-1905930#####NA 145InsecticideN-Methyl Carbamate2-yl)phenyl-N-methylcarbamate2-chloro-4,5-xylyl N-hydroxy-14357-82-5#####NA 117InsecticideN-Methyl CarbamateN-methylcarbamate2-cyclopentylphenyl3282-00-6#####NA 132InsecticideN-Methyl Carbamatemethylcarbamate2-Hydroxyphenyl10309-97-4#####NA 118InsecticideN-Methyl Carbamatemethylcarbamate3,4-Dichlorobenzyl2328-31-6#####NA 136InsecticideN-Methyl Carbamatemethylcarbamate3,5-Diisopropylphenyl330-64-3#####NA 142InsecticideN-Methyl Carbamatemethylcarbamate3-hydroxycarbofuran16655-82-6#####4074BreakdownN-Methyl Carbamateproduct3-ketocarbofuran16709-30-1NA 176NA 164BreakdownN-Methyl Carbamateproduct4-17702-57-7#####NA 142InsecticideN-Methyl Carbamate(((Dimethylamino)methylene)amino)-m-tolylmethylcarbamate4-(Methylamino)-3,5-xylyl10389-50-1#####NA 118InsecticideN-Methyl Carbamatemethylcarbamate4-(Methylformamido)-3,5-10233-94-0#####NA 118InsecticideN-Methyl Carbamatexylyl methylcarbamate4-(Methylthio)-m-tolyl3566-00-5#####NA 157InsecticideN-Methyl Carbamatemethylcarbamate4-Amino-3,5-xylyl831-76-5#####NA 117InsecticideN-Methyl Carbamatemethylcarbamate5,6,7,8-Tetrahydro-1-naphthyl1136-84-1#####NA 148InsecticideN-Methyl Carbamatemethylcarbamate6-(and 2)-chloro-3,4-xylyl8063-85-238701NA 322InsecticideN-Methyl CarbamatemethylcarbamateAldicarb116-06-398301575Insecticide,N-Methyl CarbamateNematicideAldicarb sulfoxide1646-87-3#####2361BreakdownN-Methyl CarbamateproductAldoxycarb1646-88-4#####2265BreakdownN-Methyl CarbamateproductAllyxycarb6392-46-7#####NA 133InsecticideN-Methyl CarbamateAminocarb2032-59-9444012435InsecticideN-Methyl CarbamateBendiocarb22781-23-3#####1924InsecticideN-Methyl CarbamateBufencarb2282-34-05930291InsecticideN-Methyl CarbamateBufencarb8065-36-959303NA 485InsecticideN-Methyl CarbamateBufencarb, component of (with672-04-859301NA 484InsecticideN-Methyl Carbamate059302)Butacarb2655-19-8#####NA 135InsecticideN-Methyl CarbamateButocarboxim34681-10-2NA 175NA 49InsecticideN-Methyl CarbamateButoxycarboxim34681-23-7#####2201InsecticideN-Methyl CarbamateCarbanolate671-04-5#####NA 124InsecticideN-Methyl CarbamateCarbaryl63-25-256801105Insecticide,N-Methyl CarbamatePlant GrowthRegulator,NematicideCarbofuran1563-66-290601106Insecticide,N-Methyl CarbamateNematicideCarbosulfan55285-14-8906022182InsecticideN-Methyl CarbamateCloethocarb51487-69-5#####NA 100Insecticide,N-Methyl CarbamateMolluscicideDichlormate1966-58-1#####690HerbicideN-Methyl CarbamateDioxacarb6988-21-2#####4067InsecticideN-Methyl CarbamateEthiofencarb29973-13-5#####NA 50InsecticideN-Methyl CarbamateFenethacarb30087-47-9#####NA 141InsecticideN-Methyl CarbamateFenobucarb3766-81-2NA 176NA 51InsecticideN-Methyl CarbamateFormetanate22259-30-9#####NA 150InsecticideN-Methyl CarbamateFormetanate hydrochloride23422-53-997301111InsecticideN-Methyl CarbamateIsoprocarb2631-40-5#####NA 53InsecticideN-Methyl Carbamatem-Cumenyl methylcarbamate64-00-647801NA 414InsecticideN-Methyl CarbamateMethiocarb2032-65-7#####375Insecticide,N-Methyl CarbamateMolluscicideMethiocarb sulfone2179-25-1#####4077BreakdownN-Methyl CarbamateproductMethiocarb sulfoxide267266#####4078BreakdownN-Methyl CarbamateproductMethomyl16752-77-590301383Insecticide,N-Methyl CarbamateBreakdownproductMetolcarb1129-41-5NA 202NA 201InsecticideN-Methyl CarbamateMexacarbate315-18-444201623InsecticideN-Methyl CarbamateMobam1079-33-090401NA 848InsecticideN-Methyl Carbamateo-(2-Propynyloxy)phenyl3279-46-7#####NA 138InsecticideN-Methyl CarbamatemethylcarbamateOxamyl23135-22-0#####1910Insecticide,N-Methyl CarbamateNematicidePirimicarb23103-98-2#####1875InsecticideN-Methyl CarbamatePirimicarb sulfoneNA 1050NA 1554090BreakdownN-Methyl CarbamateproductPirimicarb sulfoxideNA 1049NA 1554091BreakdownN-Methyl CarbamateproductPromacyl34264-24-9NA 209NA 209InsecticideN-Methyl CarbamatePromecarb2631-37-0#####4092InsecticideN-Methyl CarbamatePropoxur114-26-14780262InsecticideN-Methyl CarbamatePropoxur, other relatedNA 1073NA 16190062InsecticideN-Methyl CarbamateTerbutol54193880151HerbicideN-Methyl CarbamateThiocarboxime25171-63-5#####NA 156N/AN-Methyl CarbamateThiofanox39196-18-4#####2938InsecticideN-Methyl CarbamateTrimethacarb12407-86-2#####2962Insecticide,N-Methyl CarbamateMolluscicide,Dog and CatRepellentTrimethacarb, (2,3,5)-2655-15-4#####NA 882Insecticide,N-Methyl Carbamatecomponent ofMolluscicideTrimethacarb, (3,4,5)-2686-99-9#####NA 881Insecticide,N-Methyl Carbamatecomponent ofMolluscicideXMC2655-14-3NA 176NA 54InsecticideN-Methyl CarbamateXylylcarb190572NA 176NA 55InsecticideN-Methyl CarbamateAldrin309-00-2451019InsecticideOrganochlorineAldrin, other relatedNA 1069NA 16090009InsecticideOrganochlorinealpha-BHC319-84-6NA 200767InsecticideOrganochlorineArochlor (composition12767-79-217803NA 161N/AOrganochlorineunspecified, PCBs and/orPCTs)Aroclor1336-36-3178015003N/AOrganochlorineBandane8029-29-62030154InsecticideOrganochlorineBHC (other than gammaNA 1092NA 16290359InsecticideOrganochlorineisomer)BHC, beta isomer319-85-7NA 175NA 46InsecticideOrganochlorineChlordane57-74-958201130InsecticideOrganochlorineChlordane, other relatedNA 1075NA 16190130InsecticideOrganochlorineChlordane, technical12789-03-658202NA 477InsecticideOrganochlorineChlordecone143-50-027701347InsecticideOrganochlorineChlorendic Acid115-28-6NA 228NA 228N/AOrganochlorineDDD72-54-8291013002InsecticideOrganochlorineDDD6088-31-3NA 415184BreakdownOrganochlorineproductDDD, other relatedNA 1080NA 16190184BreakdownOrganochlorineproductDDE72-55-9NA 1292092BreakdownOrganochlorineproductDDT50-29-329201186InsecticideOrganochlorineDicofol115-32-210501346InsecticideOrganochlorineDieldrin60-57-145001210Insecticide,OrganochlorineBreakdownproductDieldrin, other relatedNA 1085NA 16290210InsecticideOrganochlorineDienochlor2227-17-027501468InsecticideOrganochlorineDioxin (2,3,7,8-TCDD)1746-01-6#####4068ImpurityOrganochlorineDioxin (other than 2,3,7,8-NA 1319NA 177NA 176ImpurityOrganochlorineTCDD)Endosulfan115-29-779401259InsecticideOrganochlorineEndosulfan I (alpha)959-98-879402NA 771InsecticideOrganochlorineEndosulfan II (beta)33213-65-9794034046InsecticideOrganochlorineEndosulfan sulfate1031-07-8794044047BreakdownOrganochlorineproductEndrin72-20-841601262Insecticide,OrganochlorineAvicideEndrin aldehyde7421-93-4NA 1564069BreakdownOrganochlorineproductEndrin ketone53494-70-5416015029BreakdownOrganochlorineproductEndrin, other relatedNA 1086NA 16290262InsecticideOrganochlorineHeptachlor76-44-844801317InsecticideOrganochlorineHeptachlor epoxide1024-57-3448014073BreakdownOrganochlorineproductHeptachlor, other relatedNA 1089NA 16290317InsecticideOrganochlorineHexachloro dibenzo-p-dioxin34465-46-8#####2587ImpurityOrganochlorineHexachlorobenzene118-74-161001321Microbiocide,OrganochlorineFungicide,InsecticideHexachlorocyclohexane608-73-18901NA 20InsecticideOrganochlorineHexachlorocyclopentadiene77-47-427502NA 21InsecticideOrganochlorineHexachlorodibenzofuran (as55684-94-1#####NA 161ImpurityOrganochlorineimpurity)Isodrin465-73-6NA 208NA 207InsecticideOrganochlorineKelevan4234-79-1NA 208NA 208InsecticideOrganochlorineLindane58-89-99001359Insecticide,OrganochlorineRodenticideMethoxychlor72-43-534001384InsecticideOrganochlorineMethoxychlor, other relatedNA 1093NA 16290384InsecticideOrganochlorineMirex2385-85-539201402InsecticideOrganochlorineNonachlor3734-49-4448025448InsecticideOrganochlorineOxychlordane27304-13-8NA 177NA 177BreakdownOrganochlorineproductOxychlordane, mix of isomers26880-48-8NA 177NA 177BreakdownOrganochlorineproductStrobane8001-50-120401553InsecticideOrganochlorineToxaphene8001-35-280501594InsecticideOrganochlorinetrans-Nonachlor39765-80-5NA 177NA 177InsecticideOrganochlorine(E)-Mevinphos298-01-115802NA 143InsecticideOrganophosphorus(Z)-Mevinphos338-45-415803NA 144InsecticideOrganophosphorus2,5-dichloro-alpha-2701-86-2#####NA 116InsecticideOrganophosphorus(chloromethylene)benzyldiethyl phosphate2,5-dichloro-alpha-5723-62-6#####NA 116InsecticideOrganophosphorus(dichloromethylene)benzyldiethyl phosphateAcephate30560-19-1#####1685InsecticideOrganophosphorusAcethion919-54-0#####NA 139InsecticideOrganophosphorusAcetoxon2425-25-4#####NA 139Insecticide,OrganophosphorusBreakdownproductAkton1757-18-2849011421InsecticideOrganophosphorusAkton, other relatedNA 1131NA 16691421InsecticideOrganophosphorusalpha,alpha-Dithiol bis(O,O-2782-70-9#####NA 150N/AOrganophosphorusdimethylphosphorodithioate)tolueneAmidithion919-76-659601NA 487InsecticideOrganophosphorusAmiton78-53-557302NA 473InsecticideOrganophosphorusAmiton oxalate3734-97-257301NA 472InsecticideOrganophosphorusAnilofos64249-01-0NA 202NA 201InsecticideOrganophosphorusAthidathion19691-80-6#####NA 141InsecticideOrganophosphorusAzamethiphos35575-96-3#####NA 111InsecticideOrganophosphorusAzethion72348-92-6#####NA 139InsecticideOrganophosphorusAzinphos-ethyl2642-71-9580024053InsecticideOrganophosphorusAzinphos-methyl86-50-058001314InsecticideOrganophosphorusAzinphos-methyl oxygenNA 1057NA 1574054BreakdownOrganophosphorusanalogproductAzothoate5834-96-8#####NA 118InsecticideOrganophosphorusBensulide741-58-2980170HerbicideOrganophosphorusBomyl122-10-18420177InsecticideOrganophosphorusBromophos2104-96-38706NA 106InsecticideOrganophosphorusBromophos-ethyl4824-78-6#####NA 122InsecticideOrganophosphorusButamifos36335-67-8NA 202NA 201HerbicideOrganophosphorusButathiofos90338-20-8#####2433InsecticideOrganophosphorusButonate126-22-735701255N/AOrganophosphorusCadusafos95465-99-9#####NA 14InsecticideOrganophosphorusCarbophenothion786-19-658102110InsecticideOrganophosphorusChlorethoxyphos54593-83-8#####5106InsecticideOrganophosphorusChlorfenvinphos470-90-684101306InsecticideOrganophosphorusChlormephos24934-91-6#####NA 136InsecticideOrganophosphorusChlorphoxim14816-20-7NA 207NA 206InsecticideOrganophosphorusChlorprazophos36145-08-1#####NA 136InsecticideOrganophosphorusChlorpyrifos2921-88-259101253Insecticide,OrganophosphorusNematicideChlorpyrifos oxygen analog5598-15-2591015034Insecticide,OrganophosphorusBreakdownproductChlorpyrifos-methyl5598-13-0591022468InsecticideOrganophosphorusChlorthion500-28-734501NA 300InsecticideOrganophosphorusChlorthiophos21923-23-9#####2469InsecticideOrganophosphorusChlorthiophos60238-56-4#####NA 919InsecticideOrganophosphorusChlorthiophos II77503-29-8#####NA 918InsecticideOrganophosphorusChlorthiophos III77503-28-7#####NA 917InsecticideOrganophosphoruscis-Azodrin919-44-858902NA 482InsecticideOrganophosphoruscis-Methocrotophos69632-93-5#####NA 143InsecticideOrganophosphorusCoumaphos56-72-436501165InsecticideOrganophosphorusCoumaphos, other relatedNA 1077NA 16190165InsecticideOrganophosphorusCoumithioate572-48-5#####NA 141InsecticideOrganophosphorusCrotoxyphos7700-17-658801140InsecticideOrganophosphorusCrotoxyphos, other relatedNA 1076NA 16190140InsecticideOrganophosphorusCyanofenphos13067-93-1#####NA 131InsecticideOrganophosphorusCyanophos2636-26-2#####NA 131InsecticideOrganophosphorusCyanthoate3734-95-0#####NA 131InsecticideOrganophosphorusCythioate115-93-559501NA 486InsecticideOrganophosphorusDDVP62-73-784001187Insecticide,OrganophosphorusBreakdownproductDDVP, other relatedNA 10818400190187InsecticideOrganophosphorusDemephion-O682-80-4#####NA 143Insecticide,OrganophosphorusBreakdownproductDemephion-S2587-90-8#####NA 143InsecticideOrganophosphorusDemeton8065-48-357601566Insecticide,OrganophosphorusNematicideDemeton-O298-03-357602NA 474InsecticideOrganophosphorusDemeton-O-methyl867-27-658703NA 480InsecticideOrganophosphorusDemeton-S126-75-057603NA 475InsecticideOrganophosphorusDemeton-S-methyl919-86-8NA 200NA 200InsecticideOrganophosphorusDemeton-S-methyl (mixture)8022-00-2587014063InsecticideOrganophosphorusDemeton-S-methyl sulfone17040-19-6NA 183NA 182BreakdownOrganophosphorusproduct,InsecticideDequest 2010 phosphonateNA 579NA 1052496N/AOrganophosphorusDialifor10311-84-9#####1799InsecticideOrganophosphorusDialifor, other relatedNA 1138NA 16791799InsecticideOrganophosphorusDiamidafos1754-58-1#####NA 879Insecticide,OrganophosphorusNematicideDiazinon333-41-557801198InsecticideOrganophosphorusDiazoxon962-58-3NA 1564064BreakdownOrganophosphorusproductDichlofenthion97-17-628601614Insecticide,OrganophosphorusNematicideDicrotophos141-66-23520172InsecticideOrganophosphorusDimethoate60-51-535001216InsecticideOrganophosphorusDimethoate-ethyl116-01-8#####NA 147InsecticideOrganophosphorusDioxabenzofos3811-49-2#####NA 112InsecticideOrganophosphorusDioxathion78-34-237801192InsecticideOrganophosphorusDioxathion, other relatedNA 1083NA 16190192InsecticideOrganophosphorusDiphenprofos59010-86-5#####NA 920InsecticideOrganophosphorusDisulfoton298-04-432501230Insecticide,OrganophosphorusNematicideDisulfoton sulfone216746#####NA 140InsecticideOrganophosphorusDisulfoton sulfoxide216777#####NA 140BreakdownOrganophosphorusproductDitalimfos5131-24-8#####NA 891FungicideOrganophosphorusDMCP3309-87-3#####NA 119InsecticideOrganophosphorusEdifenphos17109-49-8#####1964InsecticideOrganophosphorusEndothion319315#####NA 146InsecticideOrganophosphorusEPBP3792-59-4#####NA 155InsecticideOrganophosphorusEPN2104-64-541801263InsecticideOrganophosphorusEthephon16672-87-0998011626Plant GrowthOrganophosphorusRegulatorEthion563-12-258401268InsecticideOrganophosphorusEthion, O-analog17356-42-258402NA 478BreakdownOrganophosphorusproductEthoprop13194-48-441101404Insecticide,OrganophosphorusNematicideEthyl (2-5840-95-9#####NA 149InsecticideOrganophosphorusmercaptoethyl)carbamate, S-ester of O,O-dimethylphosphorodithioateEthyl hydrogen 1-21921-96-0#####NA 148N/AOrganophosphoruspropylphosphonateEtrimfos38260-54-7#####NA 147InsecticideOrganophosphorusFamphur52-85-759901282InsecticideOrganophosphorusFamphur, O-analog960-25-859902NA 491BreakdownOrganophosphorusproductFenamiphos22224-92-6#####1857Insecticide,OrganophosphorusNematicideFenamiphos sulfone31972-44-8NA 1564070BreakdownOrganophosphorusproductFenamiphos sulfoxide31972-43-7NA 1564071BreakdownOrganophosphorusproductFenitrothion122-14-5#####2520InsecticideOrganophosphorusFensulfothion115-90-232701181Insecticide,OrganophosphorusNematicideFenthion55-38-95330163Insecticide,OrganophosphorusAvicideFenthion oxon3254-63-5#####NA 143BreakdownOrganophosphorusproductFonofos944-22-941701254InsecticideOrganophosphorusFormothion2540-82-1#####NA 143InsecticideOrganophosphorusFosmethilan83733-82-8NA 208NA 207InsecticideOrganophosphorusFospirate5598-52-7#####1856InsecticideOrganophosphorusFosthiazate98886-44-3#####NA 109N/AOrganophosphorusFosthietan21548-32-3#####NA 928Fumigant,OrganophosphorusNematicideHeptenophos23560-59-0#####NA 122InsecticideOrganophosphorusHexylthiofos41495-67-4#####NA 132InsecticideOrganophosphorusIodofenfos18181-70-9#####NA 138InsecticideOrganophosphorusIprobenfos26087-47-8NA 203NA 202FungicideOrganophosphorusIPSP1432970NA 208NA 207InsecticideOrganophosphorusIsazophos42509-80-8#####2282InsecticideOrganophosphorusIsazophos-methyl42509-83-1#####NA 136InsecticideOrganophosphorusIsocarbophos24353-61-5#####2414InsecticideOrganophosphorusIsochlorthion2463-84-534502NA 301InsecticideOrganophosphorusIsofephos25311-71-1#####2194InsecticideOrganophosphorusIsothioate36614-38-7NA 208NA 207InsecticideOrganophosphorusIsoxathion18854-01-857802NA 476InsecticideOrganophosphorusLeptophos21609-90-5#####1676InsecticideOrganophosphorusLeptophos, other relatedNA 1135NA 16791676InsecticideOrganophosphorusLythidathion2669-32-1#####NA 147InsecticideOrganophosphorusMalaoxonNA 1054NA 1564076BreakdownOrganophosphorusproductMalathion121-75-557701367InsecticideOrganophosphorusMecarbam2595-54-2#####NA 140InsecticideOrganophosphorusMecarphon29173-31-7#####NA 156InsecticideOrganophosphorusMenazon78-57-9#####NA 134N/AOrganophosphorusMephosfolan950-10-7#####NA 131InsecticideOrganophosphorusMerphos150-50-574901293Defoliant, PlantOrganophosphorusGrowthRegulatorMerphos, other relatedNA 1088NA 16290293Defoliant, PlantOrganophosphorusGrowthRegulatorMerpofos3568-56-7#####NA 129N/AOrganophosphorusMethacrifos62610-77-9NA 189NA 188InsecticideOrganophosphorusMethamidophos10265-92-6#####1697Insecticide,OrganophosphorusBreakdownproductMethidathion950-37-8#####1689InsecticideOrganophosphorusMethidathion OANA 1065#####5040InsecticideOrganophosphorusMethyl paraoxon950-35-6535024083BreakdownOrganophosphorusproductMethyl parathion298-00-053501394Insecticide,OrganophosphorusNematicideMethyl parathion, other relatedNA 1094NA 16290394Insecticide,OrganophosphorusNematicideMethyl phenkapton3735-23-7#####NA 142N/AOrganophosphorusMethyl trithion953-17-3581013531InsecticideOrganophosphorusMethyl-carbofenthionNA 843NA 1574057InsecticideOrganophosphorusMevinphos7786-34-715801480InsecticideOrganophosphorusMevinphos (stereochemistry26718-65-0NA 200NA 200InsecticideOrganophosphorusunspecified)Mevinphos, other relatedNA 1103NA 16390480InsecticideOrganophosphorusMiral42509-80-8#####2689InsecticideOrganophosphorusMonocrotophos6923-22-45890152InsecticideOrganophosphorusMorphothion144-41-2#####NA 143InsecticideOrganophosphorusNaled300-76-534401418InsecticideOrganophosphorusNaphthalophos1491-41-4#####NA 117InsecticideOrganophosphorusO,O,S-Trimethyl2953-29-9#####NA 161ImpurityOrganophosphorusphosphorodithiate (as impurity)O,O-diethyl O-2668-92-0#####NA 138InsecticideOrganophosphorusnaphthaloximidophosphorothioateO,O-diethyl phosphoro226542NA 3382508InsecticideOrganophosphoruschloridothionateO,O-Diethyl S-(4,6-dimethyl-333-40-4#####NA 140InsecticideOrganophosphorus2-pyrimidinyl)phosphorodithioateO,O-diethyl-O-phenyl32345-29-2NA 3372507InsecticideOrganophosphorusphosphorothioateO,O-dimethyl S-(2-2674-91-158704NA 481InsecticideOrganophosphorus(ethylsulfinyl)-1-methylethyl)phosphorothioateO-(2-chloro-4-nitrophenyl) O-328-04-1#####NA 137N/AOrganophosphorusisopropylethylphosphonothioateO-(4-Nitrophenyl) O-phenyl2665-30-7#####NA 158N/AOrganophosphorusmethylphosphonothioateO-ethyl O-(4-2703-13-1#####NA 117N/AOrganophosphorus(methylthio)phenyl)methylphosphonothioateO-Ethyl S-(4-methylphenyl)333-43-7#####NA 149N/AOrganophosphorusethylphosphonodithioateO-Methyl 2-nitro-4-tolyl36001-88-4#####NA 157N/AOrganophosphorusisopropylphosphoramidothioateOmethoate1113-02-6350022285Insecticide,OrganophosphorusBreakdownproductOxydemeton-methyl301-12-258702382InsecticideOrganophosphorusParaoxon311-45-5NA 1554082BreakdownOrganophosphorusproductParathion56-38-257501459InsecticideOrganophosphorusParathion56-38-257401NA 174Insecticide,OrganophosphorusNematicideParathion, other relatedNA 1099NA 16390459Insecticide,OrganophosphorusNematicidePhenkapton2275-14-1#####NA 139InsecticideOrganophosphorusPhenthoate253180#####NA 889InsecticideOrganophosphorusPhorate298-02-257201478Insecticide,OrganophosphorusNematicidePhorate sulfone249924NA 1554084BreakdownOrganophosphorusproductPhorate sulfoxide249892NA 1554085BreakdownOrganophosphorusproductPhoratoxon2600-69-3NA 1554086BreakdownOrganophosphorusproductPhoratoxon sulfoneNA 1051NA 1554087BreakdownOrganophosphorusproductPhoratoxon sulfoxide249955NA 1554088BreakdownOrganophosphorusproductPhosalone2310-17-097701479InsecticideOrganophosphorusPhosalone OANA 1066977015041Insecticide,OrganophosphorusBreakdownproductPhosfolan947-02-4#####NA 131N/AOrganophosphorusPhosmet732-11-659201335InsecticideOrganophosphorusPhosmetoxon3735-33-9592024089BreakdownOrganophosphorusproductPhosnichlor5826-76-634503NA 302InsecticideOrganophosphorusPhosphamidon13171-21-618201482InsecticideOrganophosphorusPhosphamidon, other relatedNA 1104NA 16390482InsecticideOrganophosphorusPhostebupirim96182-53-5#####5122InsecticideOrganophosphorusPhoxim14816-18-3#####NA 159InsecticideOrganophosphorusPhoxim-methyl14816-16-1#####NA 159InsecticideOrganophosphorusPiperophos24151-93-7NA 219NA 218HerbicideOrganophosphorusPirimiphos ethyl23505-41-1#####2781InsecticideOrganophosphorusPirimiphos ethyl, O-analog36378-61-7#####NA 899BreakdownOrganophosphorusproductPirimiphos-methyl29232-93-7#####2217InsecticideOrganophosphorusPrimidophos39247-96-6#####NA 127InsecticideOrganophosphorusProfenofos41198-08-7#####2042InsecticideOrganophosphorusPropaphos7292-16-2NA 201NA 201InsecticideOrganophosphorusPropetamphos31218-83-4#####2122InsecticideOrganophosphorusPropoxon5823-13-2#####NA 139InsecticideOrganophosphorusProthidathion20276-83-9#####NA 141InsecticideOrganophosphorusProthiofos34643-46-4#####4094InsecticideOrganophosphorusProthion5969-94-8#####NA 139InsecticideOrganophosphorusProthoate2275-18-5#####NA 140InsecticideOrganophosphorusPyraclofos77458-01-6NA 183NA 182InsecticideOrganophosphorusPyrazophos13457-18-6#####NA 149FungicideOrganophosphorusPyridiphenthion119-12-053302NA 450InsecticideOrganophosphorusQuinalphos13593-03-8#####NA 145InsecticideOrganophosphorusQuinalphos-methyl13593-08-3#####NA 145InsecticideOrganophosphorusQuinitofos1776-83-6#####NA 149InsecticideOrganophosphorusQuinothion22439-40-3#####NA 140InsecticideOrganophosphorusRonnel299-84-358301517InsecticideOrganophosphorusS,S,S-tributyl78-48-874801190Defoliant, PlantOrganophosphorusphosphorotrithioateGrowthRegulatorS-(1,1-Dimethylethyl) O-ethyl83318-76-7#####NA 104InsecticideOrganophosphorusethylphosphonothioateS-(4-(1,1-329-21-5#####NA 143InsecticideOrganophosphorusdimethylethyl)phenyl) O-ethylethylphosphonodithioateSophamide37032-15-8#####NA 144InsecticideOrganophosphorusSulfotep3689-24-579501558InsecticideOrganophosphorusSulfotep, other relatedNA 1111NA 16490558InsecticideOrganophosphorusSulprofos35400-43-2#####2006InsecticideOrganophosphorusSulprofos oxon38527-90-1#####NA 125BreakdownOrganophosphorusproductTemephos3383-96-8590011InsecticideOrganophosphorusTemephos sulfoxide17210-55-859002NA 483BreakdownOrganophosphorusproductTEPP107-49-379601577InsecticideOrganophosphorusTerbufos13071-79-9#####2925Insecticide,OrganophosphorusNematicideTerbufos sulfone56070-16-7#####NA 140BreakdownOrganophosphorusproductTerbufos sulfoxide10548-10-4#####NA 140BreakdownOrganophosphorusproductTetrachlorvinphos22248-79-983702305InsecticideOrganophosphorusTetrachlorvinphos961-11-583701NA 34InsecticideOrganophosphorusThiometon640-15-3#####NA 149InsecticideOrganophosphorusThionazin297-97-2324012939InsecticideOrganophosphorusThionazin, O-analog7359-55-932402NA 297Insecticide,OrganophosphorusBreakdownproductTolclofos-methyl57018-04-9#####NA 106FungicideOrganophosphorusTriazophos24017-47-8#####3543InsecticideOrganophosphorusTrichlorfon52-68-65790188InsecticideOrganophosphorusTrichloronat327-98-0#####5001InsecticideOrganophosphorusVamidothion2275-23-2#####3544InsecticideOrganophosphorus3-iodo-2-propynyl butyl55406-53-6#####1938Fungicide,Other CarbamatecarbamateWoodPreservative6-Methyl-2-propyl-4-2532-49-2#####NA 157N/AOther Carbamatepyrimidinyl dimethylcarbamateAlanycarb83130-01-2NA 175NA 47InsecticideOther CarbamateAsulam3337-71-1#####5076HerbicideOther CarbamateAsulam, sodium salt2302-17-2#####1746HerbicideOther CarbamateBenfuracarb82560-54-1#####NA 48InsecticideOther CarbamateChlorbufam1967-16-4#####NA 157HerbicideOther CarbamateChlorprocarb23121-99-5#####NA 136HerbicideOther CarbamateChlorpropham101-21-318301141Herbicide,Other CarbamatePlant GrowthRegulatorDiethofencarb87130-20-9NA 184NA 183FungicideOther CarbamateDimetan122-15-6#####NA 112InsecticideOther CarbamateDimetilan644-64-490101NA 844InsecticideOther CarbamateFenoxycarb79127-80-3#####2283Insecticide,Other CarbamateInsect GrowthRegulatorFenoxycarb72490-01-8NA 228NA 228Insecticide,Other CarbamateInsect GrowthRegulatorIsolan119-38-0#####NA 155InsecticideOther CarbamateKarbutilate4849-32-597401691HerbicideOther CarbamateMecarbinizid27386-64-7#####NA 157N/AOther CarbamateNitrilacarb29672-19-3#####NA 129InsecticideOther CarbamatePotassium asulam14089-43-1#####NA 893HerbicideOther CarbamatePropamocarb24579-73-5#####2147FungicideOther CarbamatePropamocarb hydrochloride25606-41-1#####4022FungicideOther CarbamatePropham122-42-947601339Herbicide,Other CarbamatePlant GrowthRegulatorPyrolan87-47-8#####NA 157InsecticideOther CarbamateSwep1918-18-9846014098N/AOther CarbamateChlorfenapyr122453-73-0#####3938InsecticidePyrazolePyrazoxyfen71561-11-0NA 189NA 189HerbicidePyrazoleTebufenpyrad119168-77-390102NA 845InsecticidePyrazole(+−)-cis,trans-Deltamethrin120710-23-8#####NA 120InsecticidePyrethroid(+−)-cis-Permethrin52341-33-0#####NA 120InsecticidePyrethroid(S)-Cypermethrin66841-24-5#####3866InsecticidePyrethroid6-chloropiperonyl 2,2-70-43-9#####NA 124InsecticidePyrethroiddimethyl-3-(2-methylpropenyl)cyclopropanecarboxylateAcrinathrin101007-06-1#####NA 4InsecticidePyrethroidAllethrin584-79-2400112InsecticidePyrethroidAllethrin CoilNA 11634002NA 163InsecticidePyrethroidAllethrin, other relatedNA 1070NA 16090012InsecticidePyrethroidB-fenvalerate66267-77-4#####NA 903InsecticidePyrethroidBeta-cyfluthrin68359-37-5#####3956InsecticidePyrethroidBifenthrin82657-04-3#####2300InsecticidePyrethroidBioresmethrin28434-01-797802NA 855InsecticidePyrethroidCismethrin35764-59-197804NA 857InsecticidePyrethroidCyclethrin97-11-04052NA 69N/APyrethroidCycloprothrin63935-38-6NA 204NA 203InsecticidePyrethroidCyfluthrin68359-37-5#####2223InsecticidePyrethroidCyhalothrin68085-85-8#####NA 104InsecticidePyrethroidCypermethrin (stereochemistry52315-07-8#####NA 172InsecticidePyrethroidunspecified)Cypermethrin, alpha67375-30-8#####NA 120InsecticidePyrethroidCypermethrin, beta65731-84-2#####2171InsecticidePyrethroidCypermethrin, theta71697-59-1NA 200NA 199InsecticidePyrethroidCyphenothrin39515-40-7#####3885InsecticidePyrethroidD-Allethrin42534-61-240052293InsecticidePyrethroidD-allethrin, other relatedNA 1151NA 16892293InsecticidePyrethroidD-cis-trans Allethrin42534-61-24005NA 163InsecticidePyrethroidD-trans Allethrin28057-48-940034038InsecticidePyrethroidD-trans allethrin, other relatedNA 1154NA 17394038InsecticidePyrethroidDeltamethrin52918-63-5978053010InsecticidePyrethroidDeltamethrin (isomer52820-00-5#####NA 120InsecticidePyrethroidunspecified)Deltamethrin, other relatedNA 1153NA 16993010InsecticidePyrethroidDimethrin70-38-234101NA 299InsecticidePyrethroidEmpenthrin [(1R)isomers]54406-48-3NA 202NA 202InsecticidePyrethroidEsbiothrin28434-00-640044040InsecticidePyrethroidEsfenvalerate66230-04-4#####2321InsecticidePyrethroidFenpropathrin39515-41-8#####2234InsecticidePyrethroidFenpropathrin64257-84-7NA 201NA 200InsecticidePyrethroidFenvalerate51630-58-1#####1963InsecticidePyrethroidFenvalerate51630-58-1#####NA 173InsecticidePyrethroidFenvalerate, other relatedNA 1143NA 16791963InsecticidePyrethroidFlucythrinate70124-77-5#####2168InsecticidePyrethroidFlumethrin69770-45-2NA 219NA 218InsecticidePyrethroidFluvalinate (stereochemistry69409-94-5#####2195InsecticidePyrethroidunspecified)Furethrin17080-02-3#####NA 150InsecticidePyrethroidHalfenprox111872-58-3NA 189NA 188InsecticidePyrethroidImiprothrin72963-72-540065327InsecticidePyrethroidLambda cyhalothrin91465-08-6#####2297InsecticidePyrethroidPermethrin52645-53-1#####2008InsecticidePyrethroidPermethrin, other relatedNA 1146NA 16892008InsecticidePyrethroidPhenothrin26002-80-2690052093InsecticidePyrethroidPhenothrin, other relatedNA 1147NA 16892093InsecticidePyrethroidPrallethrin23031-36-9#####3985InsecticidePyrethroidPyrethrins and pyrethroids,68648-44-269007NA 611InsecticidePyrethroidmanufg. ResiduesResmethrin10453-86-8978012119InsecticidePyrethroidResmethrin, other relatedNA 1148NA 16892119InsecticidePyrethroidS-Bioallethrin28434-00-640044039InsecticidePyrethroidTau-fluvalinate102851-06-9NA 201NA 200InsecticidePyrethroidTefluthrin79538-32-2#####3839InsecticidePyrethroidTetramethrin7696-12-0690031695InsecticidePyrethroidTetramethrin, other relatedNA 1137NA 16791695InsecticidePyrethroidTralomethrin66841-25-6#####2329InsecticidePyrethroidTransfluthrin118712-89-3NA 206NA 205InsecticidePyrethroid(Poly-N-acetyl--D-9012-76-4#####2792Plant GrowthAnimal derivedglucosamine)-proteinRegulator,FungicideAmmoniated caseinate9005-42-9NA 5393579N/AAnimal derivedAndrosterone53-41-8#####NA 101Deer RepellentAnimal derivedAnimal gland extractsNA 63NA 1181345RodenticideAnimal derivedAnimal glueNA 792NA 1473581Rodenticide,Animal derivedBird RepellentBeef fatNA 637NA 1173585BaitAnimal derivedBone mealNA 584NA 1063589N/AAnimal derivedBone oil8001-85-21080178Dog and CatAnimal derivedRepellentCalcium salts of casein and soyNA 665NA 1231252N/AAnimal derivedCasein9000-71-9NA 1521075N/AAnimal derivedCat foodNA 796NA 1473602BaitAnimal derivedCheeseNA 222NA 4293604BaitAnimal derivedChitin1398-61-4#####NA 109NematicideAnimal derivedClam shellsNA 797NA 1473611N/AAnimal derivedCod liver oil8001-69-2316092250N/AAnimal derivedDried blood68911-49-96111315Dog and CatAnimal derivedRepellentDry milk solidsNA 149NA 2841976N/AAnimal derivedEgg shellsNA 141NA 2753649N/AAnimal derivedEggsNA 802NA 1483648N/AAnimal derivedElanco empty gelatin capsulesNA 142NA 2762543N/AAnimal derivedFish mealNA 123NA 2372571N/AAnimal derivedFish oil8016-13-5#####3658Adjuvant, DeerAnimal derivedRepellent, Dogand CatRepellentGame repellentNA 1490NA 221NA 221Deer RepellentAnimal derivedGardol137-16-61743210Dog and CatAnimal derivedRepellentGelatin9000-70-8NA 2223660InsecticideAnimal derivedGelatin capsules, R. P. SchererNA 574NA 1042577N/AAnimal derivedHydrolyzed proteinsNA 1355NA 192NA 192BaitAnimal derivedJaguarNA 76NA 1472146Deer RepellentAnimal derivedLard61789-99-9NA 1433675N/AAnimal derivedLion wasteNA 571NA 1031301Deer RepellentAnimal derivedMeatNA 53NA 1003681BaitAnimal derivedMeat mealNA 570#####3682Bait, DeerAnimal derivedRepellent, Dogand CatRepellentMeat scrapsNA 54NA 1013683BaitAnimal derivedMeat stock, Hormel #6NA 618NA 1122670BaitAnimal derivedMilk8049-98-7NA 643564N/AAnimal derivedNutria meatNA 24NA 363702BaitAnimal derivedOil of minkNA 10NA141961N/AAnimal derivedOyster shellsNA 808NA 1493714N/AAnimal derivedPig tastiesNA 594NA 1073730N/AAnimal derivedPowdered gelatinNA 760NA 1372827N/AAnimal derivedPutrescent whole egg solids51609-52-0#####1935Insecticide,Animal derivedDeer RepellentShellac9000-59-3NA 1093378N/AAnimal derivedSilkworm pupaeNA 464NA 8282855N/AAnimal derivedSodium caseinate9005-46-3NA 8363389N/AAnimal derivedSperm oil8002-24-299701NA 868N/AAnimal derivedWheyNA 560NA 1013825N/AAnimal derivedWoolNA 566NA 1023826N/AAnimal derived(−)-.alpha.-Cubebene17699-14-8#####NA 130InsecticideBotanical(7S)-Hydroprene65733-18-8#####NA 107Insect GrowthBotanicalRegulator1-naphthaleneacetamide86-86-256001422Plant GrowthBotanical,(NAD)RegulatorNaphthalene aceticacid derivati2-methoxy-5-nitro phenol,67233-85-6#####5117Plant GrowthBotanicalsodium saltRegulator2-NaphthyloxyacetamideNA 1401NA 197NA 196Plant GrowthNaphthalene aceticRegulator,acid derivati,HerbicideBotanical3,7-dimethyl-6-octanol106-22-9NA 1292140InsectBotanicalRepellent3,7-dimethyl-6-octen-1-ol150-84-5NA 3072522InsectBotanicalacetateRepellentAcacia2591766NA 6962346N/ABotanicalAlfalfaNA 635NA 1163569N/ABotanicalAlfalfa mealNA 393NA 7143570N/ABotanicalAlgin9005-38-3NA 7153571N/ABotanicalAlmond hullsNA 280NA 5473577N/ABotanicalAlmond shellsNA 636NA 1173578N/ABotanicalAlpha-ionone127-41-3#####1518Dog and CatBotanicalRepellentAlpha-pinene polymer31393-98-3NA 1533996InsecticideBotanicalAmycol potato alpha starchNA 272NA 5272387N/ABotanicalApple pomaceNA 262NA 5173582N/ABotanicalAvermectin71751-41-2#####2254InsecticideBotanicalAvermectin B165195-55-3#####NA 165InsecticideBotanicalAvermectin, other relatedNA 1156NA 17492254InsecticideBotanicalAzadirachtin11141-17-6#####2328Insecticide,BotanicalNematicideAzadirachtin B95507-03-2#####NA 989InsecticideBotanicalBalsam peruNA 660NA 1221146N/ABotanicalBarley strawNA 873NA 1605138N/ABotanicalBeeswax (yellow and white)NA 245NA 4943586N/ABotanicalBeet powderNA 246NA 4953587N/ABotanicalBeta-caryophyllene87-44-5NA 4392188N/ABotanicalBeta-pinene polymer68240-09-5NA 1533998InsecticideBotanicalBranNA 638NA 1173590N/ABotanicalBread crumbsNA 793NA 1473591BaitBotanicalBuffalo gourd root powderNA 238NA 4753928N/ABotanicalCalf's Milk ReplacerNA 1320NA 1775741N/ABotanicalCanary seedNA 583NA 1053597BaitBotanicalCapsicum oleoresin404-86-470701470InsecticideBotanicalCardboardNA 795NA 1473599N/ABotanicalCarrageenan2591943NA 4373600AdjuvantBotanicalCarrotsNA 226NA 4383601N/ABotanicalChlorophyllin11006-34-1NA 191NA 190Fungicide,Inorganic-Copper,MicrobiocideBotanicalCinerin I25402-06-669009NA 612InsecticideBotanicalCinerin II121-20-069010NA 613InsecticideBotanicalCinnamaldehyde104-55-2405062277Dog and CatBotanicalRepellent,Fungicide, Dogand CatRepellentCinnamonNA 217#####3607InsecticideBotanicalcis-ZeatinNA 1342NA 191NA 190Plant GrowthBotanicalRegulatorCitronellal106-23-0NA 223NA 223InsectBotanicalRepellentCitronellol106-22-9NA 3062139InsecticideBotanicalCitrus extractNA 1457NA 216NA 215N/ABotanicalCitrus mealNA 214NA 4073608N/ABotanicalCitrus pectinNA 215NA 4083609N/ABotanicalCitrus pulpNA 216NA 4093610N/ABotanicalClarified hydrophobic extract8002-65-1250063979InsecticideBotanicalof neem oilClarified hydrophobic neem oil8002-65-125007NA 172InsecticideBotanicalCloves, CrushedNA 962#####2333InsecticideBotanicalCoco shell flourNA 200NA 3923617N/ABotanicalCocoaNA 207NA 3983613N/ABotanicalCocoa shellsNA 640NA 1173614N/ABotanicalCoffee groundsNA 581NA 1053619N/ABotanicalComponents of etheric oils ofNA 1360NA 193NA 192InsecticideBotanicalplant originCorkNA 798NA 1473622N/ABotanicalCornNA 879NA 1695144BaitBotanicalCorn cobsNA 193NA 3833624N/ABotanicalCorn flourNA 799NA 1473625N/ABotanicalCorn gluten meal66071-96-3#####2481HerbicideBotanicalCorn product, hydrolyzedNA 710NA 1302322HerbicideBotanicalCottonNA 188NA 3763629N/ABotanicalCotton fibre cordNA 189NA 3772482N/ABotanicalCottonseed flour12751-36-9NA 1292078N/ABotanicalCottonseed mealNA 190NA 3783630N/ABotanicalCracked oatsNA 801NA 1483632BaitBotanicalCracked wheatNA 192NA 3803633BaitBotanicalCreosote, wood8021-39-425002NA 202WoodBotanicalPreservativeCube extractsNA 95871004756InsecticideBotanicalCytokinin525-79-1#####2082Plant GrowthBotanicalRegulatorCytokinin (as kinetin)525-79-1#####NA 172Plant GrowthBotanicalRegulatorDaphne oilNA 1354NA 192NA 192InsectBotanicalRepellentDerris resins other thanNA 126071001NA 172InsecticideBotanicalrotenoneDesmodiumNA 1560NA 227NA 227InsecticideBotanicalDigitalis71-63-697002NA 850N/ABotanicalDigitalis1339-93-197002NA 851N/ABotanicalDihydroazadirachtin108189-58-8#####3994Insecticide,BotanicalNematicideDMN571-58-4558025067Plant GrowthBotanicalRegulatorDouglas fir bark, groundNA 156NA 2923647N/ABotanicalEmamectin, benzoate137512-74-4#####4020InsecticideBotanicalEthylene glycol ether of pinene53404-49-242101NA 363InsecticideBotanicalEugenol97-53-0#####2095Pheromone,BotanicalFragrance, Dogand CatRepellent,Insecticide,InsectRepellentFenugreekNA 121NA 2343657N/ABotanicalFlourNA 120NA 2323659N/ABotanicalFlowers of ChamomileNA 1267#####NA 173InsecticideBotanical(Matricaria chamomilla and/orAnthemidis nobilis)Folic acid59-30-3NA 191NA 190Plant GrowthBotanicalRegulatorGarlic8000-78-0#####2213InsecticideBotanicalGeraniol106-24-1#####309Pheromone,BotanicalFragrance,Insecticide,InsectRepellent, Dogand CatRepellentGibberellic acid, 2-butoxyethyl6550-86-343803NA 371Plant GrowthBotanicalesterRegulatorGibberellin A4 mixt. With8030-53-3#####NA 952Plant GrowthBotanicalgibberellin A7RegulatorGibberellins77-06-543801310Plant GrowthBotanicalRegulatorGibberellins, potassium salt125-67-743802771Plant GrowthBotanicalRegulatorGrape pomaceNA 880NA 1695145N/ABotanicalGriseofulvin126-07-8#####NA 150N/ABotanicalGround corn cobsNA 732NA 1332583N/ABotanicalGround oatsNA 804NA 1483664BaitBotanicalGround rice hullsNA 108NA 2122584N/ABotanicalGround sesame plantNA 109#####2585Insecticide,BotanicalNematicideGuar gum9000-30-0NA 1033666AdjuvantBotanicalGum resins9000-75-399401NA 866AdjuvantBotanicalGum Thus224496784502NA 834AdjuvantBotanicalGum tragacanth9000-65-1NA 2133218AdjuvantBotanicalHearts of corn flourNA 573NA 1043667N/ABotanicalHellebore alkaloids1399-70-82001NA 65N/ABotanicalHumic acid1415-93-6NA 1342597N/ABotanicalHydroprene41096-46-2#####2244Insect GrowthBotanicalRegulatorIndole120-72-9250002614Insecticide,BotanicalInsectRepellent, Dogand CatRepellentIndole-3-acetic acid87-51-4#####NA 106Plant GrowthBotanicalRegulatorJasmolin I4466-14-269011NA 614InsecticideBotanicalJasmolin II1172-63-069012NA 615InsecticideBotanicalJuniper tar oil223154367203NA 575InsecticideBotanicalJuniperus communis ext.84603-69-067212NA 582InsecticideBotanicalLarkspur alkaloid41710-20-72202NA 66N/ABotanicalLeaves of EucalyptusNA 1277#####NA 174InsecticideBotanicalLeaves of Pennyroyal (MenthaNA 1278#####NA 174InsecticideBotanicalpulegium)LigninNA 73NA 1402640N/ABotanicalLilacin118-34-367006NA 573N/ABotanicalLinalool78-70-6#####2239Insecticide,BotanicalInsectRepellent,FragranceLocust bean gumNA 738NA 1342647AdjuvantBotanicalMedicated feedNA 644NA 1183685N/ABotanicalMillet seedNA 38NA 653692BaitBotanicalMint HerbsNA 1280#####NA 174InsecticideBotanicalMontok pepperNA 851NA 1585012InsecticideBotanicalMyrica cerifera, extract84929-34-0#####NA 123N/ABotanicalN6-Benzyladenine, mixt. with53663-71-1#####NA 953Plant GrowthBotanicalGibberellins A4 and A7RegulatorNAA86-87-356002423Plant GrowthNaphthalene aceticRegulatoracid derivati,BotanicalNAA, ethyl ester2122-70-556008749Plant GrowthNaphthalene aceticRegulatoracid derivati,BotanicalNicotine54-11-55670275InsecticideBotanicalNicotine sulfate65-30-556703430InsecticideBotanicalNOA120-23-055601432Plant GrowthNaphthalene aceticRegulatoracid derivati,BotanicalNonanoic acid112-05-0#####2739Herbicide,BotanicalFungicideOatmealNA 806NA 1493704BaitBotanicalOatsNA 16NA 263705BaitBotanicalOil of cedarwood8000-27-9405051011Insecticide,BotanicalFungicideOil of hardwoodNA 675672011639MicrobiocideBotanicalOil of pine tar2227495670022246Insecticide,BotanicalMicrobiocideOils, cedarwood, Texan68990-83-011524NA 118Insecticide,BotanicalFungicideOnion extractNA 1349NA 192NA 191N/ABotanicalOnionsNA 807NA 1493711N/ABotanicalOrange pulpNA 9NA 133712N/ABotanicalp-Menthane-3,8-diol42822-86-6115505255InsectBotanicalRepellentPaloja9000-28-6#####NA 880N/ABotanicalPapain9001-73-4NA 1493717RodenticideBotanicalPaperNA 598NA 1073718N/ABotanicalPaprikaNA 383NA 6923719N/ABotanicalPeanut butterNA 373NA 6812735BaitBotanicalPeanut shellsNA 375NA 6833723N/ABotanicalPeanutsNA 374NA 6823533BaitBotanicalPeat mossNA 809NA 1493724N/ABotanicalPecan shell flourNA 376NA 6843725N/ABotanicalPectin9000-69-5NA 1183726N/ABotanicalPepperNA 1348NA 192NA 191Insecticide,BotanicalDeer RepellentPeppermintNA 365NA 6682332Insecticide,BotanicalFragrancePhenylethyl propionate122-70-3#####2094Fragrance,BotanicalPheromone,Insecticide,InsectRepellent, Dogand CatRepellentPine oil222749567002485Insecticide,BotanicalMicrobiocidePine soapNA 1032NA 1271993Insecticide,BotanicalMicrobiocidePine tar8011-48-1672041574Insecticide,BotanicalMicrobiocidePine tar oil91995-59-467205NA 576Insecticide,BotanicalMicrobiocidePinene80-56-8670042187InsecticideBotanicalPinene1330-16-167001NA 572InsecticideBotanicalPlant carbolineumsNA 1454NA 215NA 215Insecticide,BotanicalFungicidePlant extract (derived fromNA 917#####5453NematicideBotanicalQuercus falcata, Opuntialindheimeri, Rhus aromatica,and Rhizophoria mangletissues)Polymerized pineneNA 399NA 7222043InsecticideBotanicalPotatoesNA 436NA 7863772N/ABotanicalPoultry feedNA 437NA 7873773N/ABotanicalPyrethrin coilsNA 116569004NA 164InsecticideBotanicalPyrethrin I121-21-1NA 213NA 213InsecticideBotanicalPyrethrin II121-29-969006NA 610InsecticideBotanicalPyrethrins8003-34-769001510InsecticideBotanicalPyrethrins, other relatedNA 1108NA 16490510InsecticideBotanicalPyrethrum narcNA 1000690001461InsecticideBotanicalPyrethrum powder other than8003-34-769002NA 164InsecticideBotanicalpyrethrinsQuassiaNA 450NA 8063778InsecticideBotanicalQuillaja68990-67-0NA 1503779N/ABotanicalRaisinsNA 647NA 1193780BaitBotanicalRed dog flourNA 452NA 8113782N/ABotanicalRed pepperNA 107707031094Dog and CatBotanicalRepellentRed squill glycoside507-60-870801514RodenticideBotanicalRepellants (by smell) of animalNA 1373NA 194NA 193Dog and CatBotanicalor plant originRepellent, DeerRepellentResins, oleo-, capsicum8023-77-670704NA 665InsecticideBotanicalRiceNA 812NA 1503783N/ABotanicalRice hullsNA 813NA 1503784N/ABotanicalRosemaryNA 453#####2331N/ABotanicalRosin9014-63-5NA 8123785N/ABotanicalRosin oil8002-16-240508NA 341N/ABotanicalRosin, partially dimerizedNA 454NA 8133786N/ABotanicalRosin, partially hydrogenated65997-06-0NA 1503787N/ABotanicalRotenone83-79-471003518InsecticideBotanicalRotenone, other relatedNA 1109NA 16490518InsecticideBotanicalRubber2594048NA 8143788N/ABotanicalRyanodineNA 130571502NA 175InsecticideBotanicalRyanodine alkaloid15662-33-671501520InsecticideBotanicalRye flourNA 648NA 1193789N/ABotanicalSabadilla alkaloids22451802201521InsecticideBotanicalSafrole94-59-7979013376N/ABotanicalSaponin8047-15-2970045033N/ABotanicalSawdustNA 1306#####1316AdjuvantBotanicalScratch feedNA 649NA 1193792N/ABotanicalSea-algae extractNA 1352NA 192NA 191Plant GrowthBotanicalRegulator,AdjuvantSeaweedNA 814NA 1503793N/ABotanicalSodium 2-nitrophenoxide824-39-5#####5118Plant GrowthBotanicalRegulatorSodium 4-nitrophenoxide824-78-2#####5119Plant GrowthBotanicalRegulatorSorghum, grainNA 478NA 8823904N/ABotanicalSoy flourNA 482NA 8863809N/ABotanicalSoy proteinNA 483NA 8873810N/ABotanicalSoybean extractNA 1353NA 192NA 191N/ABotanicalSoybean hullsNA 481NA 8853807N/ABotanicalSoybean mealNA 817NA 1503808N/ABotanicalSqualane111-01-3455032887N/ABotanicalSugarbeet mealNA 499NA 9103813N/ABotanicalSunflower seedsNA 650NA 1193815BaitBotanicalSynthetic vegetable gums9004-64-2NA 9211835AdjuvantBotanicalTall oil8002-26-4672112912AdjuvantBotanicalTall oil acids61790-12-3NA 1241389AdjuvantBotanicalTar oils, from distillation of8002-29-767202NA 574Insecticide,Botanicalwood tarHerbicideThuringiensin, calcium23526-02-564042941InsecticideBotanicaltechnicalThymeNA 527#####2330InsectBotanicalRepellent,InsecticideTobaccoNA 1011NA 9593932InsecticideBotanicalTobacco dust8037-19-256704NA 469InsecticideBotanicalTrimethoxybenzene135-77-3405155064Insecticide,BotanicalInsectRepellent, Dogand CatRepellentTung oilNA 547NA 9973821N/ABotanicalVerbenone1196-01-6#####NA 108InsectBotanicalRepellentWalnut flourNA 555NA 1013823N/ABotanicalWalnut shells, groundNA 556NA 1012986N/ABotanicalWheatNA 819NA 1513824N/ABotanicalWheat flourNA 674NA 1251577N/ABotanicalWhite pepperNA 1311NA 178NA 177InsecticideBotanicalWood powderNA 565NA 1021463N/ABotanicalWood rosin224503167208NA 579N/ABotanicalWood tar91722-33-767206NA 577InsecticideBotanicalXanthan gum11138-66-2NA 1022272AdjuvantBotanicalAgrobacterium radiobacter varNA 1435NA 211NA 210FungicideMicrobialradiobacterAgrobacterium radiobacterNA 693NA 1271984FungicideMicrobialAgrobacterium radiobacterNA 925#####NA 167FungicideMicrobial(strain K84)Agrobacterium radiobacterNA 92164745477FungicideMicrobialstrain K1026Agrobacterium vitisNA 1536NA 224NA 224FungicideMicrobialAgrotis segetum granulosisNA 1391NA 196NA 195InsecticideMicrobialvirusAmpelomyces quisqualisNA 270NA 5252385FungicideMicrobialAmpelomyces quisqualisNA 121721007NA 170FungicideMicrobialisolate M-10Anagrapha falcifera multi-NA 862#####5089InsecticideMicrobialnuclear polyhedrosis virus(AFMNPV)Aschersonia aleyrodisNA 1392NA 196NA 195InsecticideMicrobialBacillus cereus strain UW85NA 1218#####NA 170Plant GrowthMicrobialRegulatorBacillus cereus, strain BP01NA 903NA 1725183InsecticideMicrobialBacillus popilliaeNA 257NA 5092183FungicideMicrobialBacillus popilliae and B. lentimorbusNA 121954501NA 170FungicideMicrobialBacillus sphaericus143447-72-7#####2274InsecticideMicrobialBacillus sphaericus, serotype143447-72-7#####2409InsecticideMicrobialH-5A5B, strain 2362Bacillus subtilis GBO3NA 855#####3945FungicideMicrobialBacillus subtilis isolate B246NA 1538NA 225NA 224FungicideMicrobialBacillus subtilis MBI 600NA 864#####5120FungicideMicrobialBacillus subtilis var.NA 12206480NA 170Fungicide,MicrobialAmyloliquefaciens StrainPlant GrowthFZB24RegulatorBacillus thuringiensis (berliner)68038-71-1640086InsecticideMicrobialBacillus thuringiensis68038-71-164263843InsecticideMicrobial(berliner), subsp. Aizawai, GC-91 proteinBacillus thuringiensis68038-71-164003856InsecticideMicrobial(berliner), subsp. Aizawai,serotype H-7Bacillus thuringiensis68038-71-164013857InsecticideMicrobial(berliner), subsp. Israelensis,serotype H-14Bacillus thuringiensis68038-71-164023970InsecticideMicrobial(berliner), subsp. Kurstakistrain SA-12Bacillus thuringiensis68038-71-164023858InsecticideMicrobial(berliner), subsp. Kurstaki,serotype 3a, 3bBacillus thuringiensis68038-71-164243859InsecticideMicrobial(berliner), subsp. Kurstaki,strain EG2348Bacillus thuringiensis68038-71-164233860InsecticideMicrobial(berliner), subsp. Kurstaki,strain EG2371Bacillus thuringiensis68038-71-164223861InsecticideMicrobial(berliner), subsp. Kurstaki,strain EG2424Bacillus thuringiensis68038-71-164023862InsecticideMicrobial(berliner), subsp. Kurstaki,strain SA-11Bacillus thuringiensisNA 148164003863InsecticideMicrobial(berliner), subsp. Morrisoni,serotype 8a8bBacillus thuringiensis68038-71-164003864InsecticideMicrobial(berliner), subsp. San DiegoBacillus thuringiensis68038-71-164042410InsecticideMicrobialdarstadiensisBacillus thuringiensis sub.68038-71-164485051InsecticideMicrobialKurstaki strain EG7673coleopteran active toxinBacillus thuringiensis sub.68038-71-164475049InsecticideMicrobialKurstaki strain EG7673lepidopteran active toxinBacillus thuringiensis subsp.NA 12246403NA 170InsecticideMicrobialAizawaiBacillus thuringiensis subsp.68038-71-164025004InsecticideMicrobialKurstaki, geneticallyengineered strain AGRO1 byAgrevoBacillus thuringiensis subsp.68038-71-164025005InsecticideMicrobialKurstaki, geneticallyengineered strain AGRO2 byAgrevoBacillus thuringiensis subsp.NA 1232#####NA 171InsecticideMicrobialSan DiegoBacillus thuringiensis subsp.68038-71-164055043InsecticideMicrobialTenebrionisBacillus thuringiensis subspec.68038-71-1NA 1693972InsecticideMicrobialTenebrionis delta endotoxinBacillus thuringiensisNA 12346476NA 171InsecticideMicrobialsubspecies Israelensis strainEG2215Bacillus thuringiensis68038-71-164014018InsecticideMicrobialsubspecies Israelensis, strainIPS-78Bacillus thuringiensis68038-71-164074024InsecticideMicrobialsubspecies kurstaki strain BMP123Bacillus thuringiensis68038-71-164025010InsecticideMicrobialsubspecies Kurstaki strain HD-1, lepidopteran active toxinBacillus thuringiensis68038-71-164533988InsecticideMicrobialsubspecies kurstaki, geneticallyengineered strain EG7841lepidopteran active toxinBacillus thuringiensis var.NA 12386445NA 171InsecticideMicrobialkurstaki delta endotoxin proteinas produced by the Cry1A(c)gene and its controllingsequencesBacillus thuringiensis var.68038-71-164523978InsecticideMicrobialKurstaki strain M-200 proteintoxinBacillus thuringiensis var.68038-71-164023962InsecticideMicrobialKurstaki, geneticallyengineered strain ECX 9441Bacillus thuringiensis var.68038-71-164595325InsecticideMicrobialKurstaki, geneticallyengineered strain EG7826Lepidopteran active toxinNeodiprion sertifer nuclearNA 1389NA 196NA 195N/AMicrobialpolyhedrosis virusNosema locustae sporesNA 20#####2137InsecticideMicrobialNuclear polyhedrosis virusNA 1451NA 215NA 214InsecticideMicrobialNuclear polyhedrosis virus ofNA 1430NA 213NA 213N/AMicrobialHelicoverpea zeaNuclear polyhedrosis virus ofNA 1510NA 222NA 222InsecticideMicrobialred-headed pine sawflyNystatin (streotomyces1400-61-9#####NA 115N/AMicrobialnoursei) (withdrawn: 23614-R:pm24)Paecilomyces fumosoroseusNA 831#####3964InsecticideMicrobialapopka strain 97Paecilomyces Lilacinus StrainNA 1439NA 213NA 213InsecticideMicrobial251Penicillin G, potassium saltNA 666NA 1231283N/AMicrobialPeniophora giganteaNA 1462NA 217NA 216FungicideMicrobialPhlebiopsis giganteaNA 1388NA 196NA 195FungicideMicrobialPhytophthora palmivora,NA 860#####5078HerbicideMicrobialchlamydospores ofPolyhedral inclusion bodies ofNA 593#####2009InsecticideMicrobialDouglas fir tussock mothnuclear polyhedrosis virusPolyhedral inclusion bodies ofNA 1289#####NA 175InsecticideMicrobialgypsy moth nucleopolyhedrosisvirusPolyhedral inclusion bodies ofNA 1290#####NA 175InsecticideMicrobialN. sertiferPolyhedral occlusion bodiesNA 835#####4028InsecticideMicrobial(OB's) of the nuclearpolyhedrosis virus ofHelicoverpa zea (cornearworm)Polyhedral occlusion bodiesNA 1292#####NA 175InsecticideMicrobial(OBs) of the nuclearpolyhedrosis virus ofAutographa californica (alfalfalooper)Polyhedral occlusion bodiesNA 830NA 1534007InsecticideMicrobial(OBs) of the nuclearpolyhedrosis virus ofSpodoptera exiguaPolyhedral occlusion bodies ofNA 1293#####NA 175InsecticideMicrobialthe beet armyworm nuclearpolyhedrosis virusPseudomonas aureofaciensNA 12966473NA 175FungicideMicrobialstrain Tx-1Pseudomonas cepacia typeNA 44964193926Fungicide,MicrobialWisconsinNematicidePseudomonas chlororaphisNA 902NA 1725182FungicideMicrobialPseudomonas chlororaphisNA 14896478NA 220FungicideMicrobialstrain 63-28Pseudomonas fluorescens EG-NA 85864405045FungicideMicrobial1053Pseudomonas fluorescensNA 86764393949FungicideMicrobial1629RSPseudomonas fluorescensNA 102064382842FungicideMicrobialA506Pseudomonas fluorescensNA 86864203968FungicideMicrobialstrain NCIB 12089Pseudomonas syringae strainNA 897NA 1713950N/AMicrobialAGS31 Psedomonas syringaestrain PS31Pseudomonas syringae strainNA 83664513967FungicideMicrobialESC-11Pseudomonas syringae, strain68602-93-764112824FungicideMicrobial742 RSPseudomonas syringae, strain68583-32-464413960FungicideMicrobialESC-10Puccinia canaliculataNA 865#####5121HerbicideMicrobial(Schweinitz) Lagerheim(ATCC #40199)QST 713 strain of driedNA 91564795447FungicideMicrobialBacillus subtilisRabbit CalicivirusNA 1441NA 214NA 213RodentMicrobialRepellentRhizobium leguminosarumNA 1556NA 226NA 226InsecticideMicrobialbiovar phaseoliRhizobium leguminosarumNA 1557NA 226NA 226InsecticideMicrobialviciaeTJ 9Rhizobium melilotiNA 1558NA 227NA 226InsecticideMicrobialSpinosad131929-60-7#####3983InsecticideMicrobialSpinosyn D131929-63-0#####NA 907InsecticideMicrobialSpores and mycelium spores ofNA 1446NA 214NA 214FungicideMicrobialPhlebiopsis giganteaSpores of Bacillus popilliaeNA 131054502NA 176FungicideMicrobialSpores of GliocladiumNA 1453NA 215NA 215FungicideMicrobialcatenulatumStreptomyces griseoviridisNA 875#####3937FungicideMicrobialstrain K61Summerfruit tortrix mothNA 1491NA 221NA 221InsecticideMicrobialgranulosis virusTomato mosaic virusNA 1387NA 196NA 195N/AMicrobialTrichoderma harzianum67892-34-6#####NA 106FungicideMicrobial(ATCC 20476)Trichoderma harzianum rifai67892-31-3#####3977FungicideMicrobialstrain KRL-AG2Trichoderma harzianum Rifai67892-31-3#####4016FungicideMicrobialstrain T-39Trichoderma polysporum67892-31-3#####NA 176FungicideMicrobial(ATCC 20475)Trichoderma polysporum rifaiNA 1067NA 1595101N/AMicrobialVerticillium dahliae Kleb.NA 1386NA 196NA 195FungicideMicrobialVerticillium lecanii67892-35-76421NA 96InsecticideMicrobialXanthomonas campestris pv.NA 910NA 1745317HerbicideMicrobialPoannuaYeastNA 652NA 1193827N/AMicrobialAllyl isothiocyanate57-06-749011010InsecticideOil - essentialAlmond, bitter8013-76-1NA 5463576N/AOil - essentialAloe vera oilNA 918NA 1755454N/AOil - essentialBlend of oils: of lemongrass, ofNA 1499NA 221NA 221InsecticideOil - essentialcitronella, of orange, ofbergamot; geraniol, iononealpha, methyl salicylate andallylisothiocCamphor76-22-215602102Insecticide,Oil - essentialFungicide,MicrobiocideCamphor oil8008-51-315601NA 142Insecticide,Oil - essentialFungicide,MicrobiocideCanadian balsam8007-47-467209NA 580Insecticide,Oil - essentialFungicideCedar leaf oil8007-20-340507NA 340Insecticide,Oil - essentialFungicideCinnamon oilNA 922NA 1755577N/AOil - essentialClove oil8000-34-8#####5018N/AOil - essentialEssential oils8014-17-3NA 121873InsecticideOil - essentialEucalyptus oil8000-48-440503281InsectOil - essentialRepellent,InsecticideFir needle oil8021-28-1#####NA 110N/AOil - essentialLavandin oil8022-15-9405005017InsectOil - essentialRepellent,Insecticide,Dog and CatRepellentLemon peel oil8020-19-740518NA 346N/AOil - essentialLime Oil8008-26-2NA 213NA 212InsecticideOil - essentialLimonene138-86-379701979InsectOil - essentialRepellent,Insecticide,Dog and CatRepellentLimonene138-86-3797012531InsecticideOil - essentialMixture citronella oil, citrusNA 1493NA 221NA 221InsectOil - essentialoil, eucalyptus oil, pine oilRepellentOil of ambergis8038-65-1#####NA 105N/AOil - essentialOil of anise8007-70-343011051InsectOil - essentialRepellent,Insecticide,Dog and CatRepellentOil of bay8006-78-8405202072N/AOil - essentialOil of bergamot8007-75-8#####1517InsectOil - essentialRepellent,Insecticide,Dog and CatRepellentOil of black pepperNA 1521NA 223NA 223InsecticideOil - essentialOil of cajeput8008-98-840504NA 339N/AOil - essentialOil of camphor sassafrassy8006-80-215603897N/AOil - essentialOil of chamomile (Matricaria8002-66-2#####NA 104InsecticideOil - essentialchamomilla and/or Anthemidisnobilis)Oil of chenopodium8006-99-3NA 181524N/AOil - essentialOil of citronella8000-29-121901143InsectOil - essentialRepellent, Dogand CatRepellentOil of citrusNA 13NA 191931InsectOil - essentialRepellentOil of geranium8000-46-2#####1887FragranceOil - essentialOil of jasmine8022-96-6405015063InsecticideOil - essentialOil of jojoba61789-91-1672003833Insecticide,Oil - essentialInsectRepellent,Fungicide, Dogand CatRepellentOil of lavender8000-28-0#####1888InsecticideOil - essentialOil of lemon8008-56-8NA 120440N/AOil - essentialOil of lemongrass5392-40-5405101009Insecticide,Oil - essentialPheromoneOil of lemongrass2229107405021136InsectOil - essentialRepellent,InsecticideOil of mustard57-06-749011153InsectOil - essentialRepellent,Insecticide,Dog and CatRepellentOil of orange8008-57-940517441InsectOil - essentialRepellent,Insecticide,Dog and CatRepellentOil of pennyroyal8007-44-1405091325InsecticideOil - essentialOil of peppermint8006-90-4NA 6692058InsecticideOil - essentialOil of rosemary8000-25-7#####5450InsecticideOil - essentialOil of rue8014-29-7405192206N/AOil - essentialOil of spearmint8008-79-5#####1508N/AOil - essentialOil of thyme8007-46-3#####NA 159N/AOil - essentialOil of wintergreen119-36-876601746InsecticideOil - essentialOils, tea-tree68647-73-428853NA 211N/AOil - essentialOrange pith oilNA 1461NA 217NA 216InsecticideOil - essentialPerfume, cherry fragrance oilNA 751NA 1362743FragranceOil - essential#493Phytelene of marigold70892-20-5#####NA 976N/AOil - essentialPhytelene of marigold84776-23-8#####NA 977N/AOil - essentialTansy, sage and lavenderNA 1452NA 215NA 214InsecticideOil - essentialextractsVanillin121-33-5#####5149N/AOil - essentialCanola oil120962-03-0113325332Insecticide,Oil - vegetableAdjuvantCastor oil8001-79-4316081013Rodenticide,Oil - vegetableInsecticide,InsectRepellentCoconut oil8001-31-8#####NA 124N/AOil - vegetableCoconut oil monoethanolamine68140-00-1691791361Adjuvant,Oil - vegetableSoap/SurfactantCorn oil8001-30-7NA 1173626N/AOil - vegetableCottonseed oil8001-29-4316021015InsecticideOil - vegetableEmulsifiable methylatedNA 907NA 1735224Insecticide,Oil - vegetablevegetable oilAdjuvantFir needle oil, siberian8021-29-2NA 2362570N/AOil - vegetableHydrogenated castor oil8001-78-3316043830Bird RepellentOil - vegetableHydrogenated soybean oil8016-70-4NA 1863670N/AOil - vegetableHydrogenated vegetable oilsNA 881NA 1695146N/AOil - vegetableLinseed oil with driersNA 61NA 1162645N/AOil - vegetableLinseed oil, boiled68553-15-1NA 1152644N/AOil - vegetableMethyl soyate68919-53-9NA 1463519AdjuvantOil - vegetableOil of linseed8001-26-1316032248N/AOil - vegetableOlive oil8001-25-0316103710N/AOil - vegetablePalm oilNA 749NA 1362731N/AOil - vegetablePeanut oil2227315NA 1183722N/AOil - vegetablePlant oils (including rape seedNA 1351NA 192NA 191InsecticideOil - vegetableoil)Rapeseed oil8002-13-9NA 220NA 219InsecticideOil - vegetableSafflower oil8001-23-8NA 1241510N/AOil - vegetableSesame oil8008-74-0724011221N/AOil - vegetableSoybean oil8001-22-7316052335Insecticide,Oil - vegetableAdjuvantVegetable oil8008-89-7NA 1111231InsecticideOil - vegetableVegetable oil modifiedNA 552NA 1002981N/AOil - vegetablephenolic resinVegetable wax8001-39-6995011441N/AOil - vegetableWeed oilNA 558NA 1011694N/AOil - vegetableWheat germ oilNA 559NA 1012988N/AOil - vegetable(1R-exo)-Brevicomin20290-99-7#####NA 106PheromonePheromone(4E-7Z)-4,7-Tridecadien-1-yl-NA 1428NA 199NA 198PheromonePheromoneacetate(4Z-9Z)-7,9-Dodecadien-1-olNA 1412NA 198NA 197PheromonePheromone(E)-5-decen-1-ol56578-18-8780385315PheromonePheromone(E)-10-Dodecenyl acetate35153-09-4NA 187NA 186PheromonePheromone(E)-11-Tetradecenyl acetate33189-72-9#####5022PheromonePheromone(E)-2,6-dimethyl-2,6-141-27-5NA 213307PheromonePheromoneoctadienal(E)-4-tridecen-1-yl-acetate72269-48-8#####2199PheromonePheromone(E)-5-Decenol56578-18-8780383974PheromonePheromone(E)-5-Decenyl acetate38421-90-8#####3975PheromonePheromone(E)-6-dodecenyl acetate29868-16-4#####NA 958PheromonePheromone(E)-9-decen-1-ol56578-18-8780385071PheromonePheromone(E)-9-dodecen-1-ol, acetate35148-19-7#####2141PheromonePheromone(E)-9-Tricosene35857-62-6NA 200NA 199PheromonePheromone(E)7-(Z)9-DodecadienylNA 1413NA 198NA 197PheromonePheromoneacetate(E,Z)-3,13-octadecadien-1-ol53120-26-6#####NA 955PheromonePheromoneacetate(E/Z)-8-Dodecenyl acetateNA 1415NA 198NA 197PheromonePheromone(R,Z)-5-(1-decenyl) dihydro-2-64726-91-6#####2096PheromonePheromone(3H)-furanone(Z)-(3,3-26532-24-1#####5081PheromonePheromonedimethylcyclohexylidene)acetaldehyde(Z)-11-hexadecen-1-ol56683-54-6#####NA 971PheromonePheromone(Z)-11-Hexadecen-1-ol56683-54-6NA 193NA 192PheromonePheromone(Z)-11-hexadecenal53939-28-9#####2126PheromonePheromone(Z)-11-hexadecenyl acetate60037-58-3#####NA 111PheromonePheromone(Z)-11-Tetradecen-1-yl-acetate20711-10-8NA 199NA 199PheromonePheromone(Z)-11-Tetradecenyl acetate20711-10-8#####5023PheromonePheromone(Z)-13-OctadecanolNA 1423NA 199NA 198PheromonePheromone(Z)-13-Octadecenal58594-45-9#####NA 111PheromonePheromone(Z)-13-Octadecenyl acetate34010-21-4#####5316PheromonePheromone(Z)-2-(3,3-dimethyl cyclo26532-23-0#####5079PheromonePheromonehexylidene)ethanol(Z)-3-Methyl-6-isopropenyl--9-NA 1420NA 198NA 198PheromonePheromonedecen-1-yl acetate(Z)-3-Methyl-6-isopropenyl-NA 1419NA 198NA 198PheromonePheromone3,4-decadien-1-yl(Z)-4-tridecen-l-yl-acetate65954-19-0#####2200PheromonePheromone(Z)-5-Decenyl acetate67446-07-5NA 198NA 197PheromonePheromone(Z)-5-Dodecen-1-yl acetate16676-96-3NA 187NA 186PheromonePheromone(Z)-6-dodecenyl acetate16974-12-2#####NA 957PheromonePheromone(Z)-6-Heneicosane-11-one54844-65-4#####NA 110PheromonePheromone(Z)-7-hexadecenal56797-40-1#####NA 972PheromonePheromone(Z)-7-TetradecanolNA 1427NA 199NA 198PheromonePheromone(Z)-7-Tetradecenal65128-96-3NA 187NA 186PheromonePheromone(Z)-9-dodecenyl acetate16974-11-1#####2142PheromonePheromone(Z)-9-hexadecenal56219-04-6#####NA 973PheromonePheromone(Z)-9-tetradecen-1-ol35153-15-2#####5618PheromonePheromone(Z)-9-tetradecenal53939-27-8#####2209PheromonePheromone(Z)-9-Tetradecenyl acetate16725-53-4NA 187NA 186PheromonePheromone(Z)-9-Tricosene27519-02-4#####NA 883PheromonePheromone(Z,E) 7,11-hexadecaclien-1-olNA 1144NA 16891997PheromonePheromoneacetate, other related(Z,E)-7,11-hexadecadien-1-yl51607-94-4#####1997PheromonePheromoneacetate(Z,E)-7,11-hexadecadien-1-yl53042-79-8#####NA 933PheromonePheromoneacetate(Z,E)-8,10-dodecadienylNA 1561NA 227NA 227PheromonePheromoneacetate(Z,E)-9,11-Tetradecadien-1-yl50767-79-8NA 199NA 198PheromonePheromoneacetate(Z,E)-9,12-tetradecadienyl31654-77-0#####5617PheromonePheromoneacetate(Z,Z) 7,11-hexadecadien-1-olNA 1145NA 16891998PheromonePheromoneacetate, other related(Z,Z) Octadienyl acetateNA 1422NA 199NA 198PheromonePheromone(Z,Z)-11,13-hexadecadienal71317-73-27115314PheromonePheromone(Z,Z)-3,13-octadecadien-1-ol53120-27-7#####NA 954PheromonePheromoneacetate(Z,Z)-7,11-hexadecadien-1-yl52207-99-5#####1998PheromonePheromoneacetate(Z,Z)-7,11-Hexadecadienyl52207-99-5NA 198NA 197PheromonePheromoneacetate1,7-Dioxaspiro-5,5-undecane180-84-7NA 186NA 186PheromonePheromone1-Methylbutyl decanoate55195-26-1#####NA 100PheromonePheromone1-Octen-3-ol3391-86-4690374029Pheromone,PheromoneFragrance,InsectRepellent, Dogand CatRepellent11-(E)-Tetradecen-1-ol35153-18-5#####5108PheromonePheromone11-(Z)-Tetradecen-1-ol34010-15-6#####NA 109PheromonePheromone2-cyclopenten-1-one, 2-80-71-74049NA 68Pheromone,Pheromonehydroxy-3-methyl-Fragrance2-methyl-7(R),8(S)-epoxy29804-22-6#####2165PheromonePheromoneoctadecane3(S)-Methyl-6-isopropenyl-9-NA 1535NA 224NA 224PheromonePheromonedodecadien-1yl acetate3,7,11-trimethyl-2,6,10-4601-84-0NA 9832269PheromonePheromonedodecatriene-1-ol3-Methyl-2-cyclohexen-1-one1193-18-6#####NA 124InsectPheromoneRepellent,Pheromone4-(p-acetoxyphenyl)-2-609379#####NA 106PheromonePheromonebutanone4-Methyl-3-heptanol14979-39-6#####NA 962PheromonePheromone7,11-hexadecadien-1-ol, acetate50933-33-0#####NA 934PheromonePheromone7,8-Epoxi-2-methyl-octadecaneNA 1417NA 198NA 197PheromonePheromone8-dodecene-1-ol, other relatedNA 1150NA 16892253PheromonePheromone9-tetradecen-1-ol, formate, (Z)-56218-79-2#####NA 967PheromonePheromoneAcetaldehyde,(3,3-26532-25-2#####5080PheromonePheromonedimethylcyclohexylidene)-,(E)beta-Farnesene18794-84-8#####NA 110PheromonePheromoneCis-11-tetradecenyl acetate20711-10-8#####5038PheromonePheromoneDistilled cubeb oil8007-87-2#####NA 960PheromonePheromoneDodecadienalNA 1547NA 226NA 225PheromonePheromoneE,E-8,10-dodecadien-1-ol33956-49-9#####1851PheromonePheromoneE-3,3-dimethyl-delta,alpha-NA 951NA 3152193PheromonePheromonecyclohexane ethanalE-8-dodeceneNA 1532NA 224NA 224PheromonePheromoneE-8-dodecenyl acetate38363-29-0#####2252PheromonePheromoneFarnesol4602-84-0#####2564PheromonePheromoneFrontalin28401-39-0#####NA 985PheromonePheromoneFrontalin + alpha-pinene12701-72-3#####NA 986PheromonePheromonemixtureGerman cockroach pheromoneNA 871290285132PheromonePheromoneIsoamyl acetate123-92-2NA 1671422FragrancePheromoneIsomate LBAMNA 1438NA 213NA 212PheromonePheromoneIsomate OFM RossoNA 1426NA 213NA 212PheromonePheromoneLauryl alcohol112-53-815092343Pheromone,Pheromone,AdjuvantAlcohol/EtherLuretape (Grandlure)11104-05-5#####NA 923PheromonePheromoneMethyl-trans-6-nonenoateNA 1421NA 199NA 198PheromonePheromoneMultilure60018-97-5#####NA 963PheromonePheromoneMultistriatin59014-03-8#####NA 961PheromonePheromoneMuscalure27519-02-4#####1858PheromonePheromoneMyrcene123-35-3#####2189PheromonePheromoneNerolidol7212-44-4#####2268PheromonePheromoneNerolidol7212-44-4#####2701PheromonePheromonePentyl valerate2173-56-0#####1809PheromonePheromonePeriplanone B61228-92-0#####2766PheromonePheromonePherodimNA 1424NA 199NA 198PheromonePheromonePronumoneNA 1425NA 199NA 198PheromonePheromoneSerricorninNA 1343NA 191NA 190PheromonePheromoneTetradecanal124-25-4#####NA 975PheromonePheromoneTrans-11-tetradecenyl acetate33189-72-9#####5039PheromonePheromonetrans-6-Nonen-1-olNA 1404NA 197NA 197PheromonePheromoneTrimedlure12002-53-8#####NA 199PheromonePheromoneZ-2-isopropenyl-1-methyl26532-22-9#####2190PheromonePheromonecyclobutane ethanolZ-3,3-dimethyl-delta,alpha-NA 952NA 3162192PheromonePheromonecyclohexane ethanalZ-3,3-dimethyl-delta,beta-NA 706NA 1292191PheromonePheromonecyclohexane ethanolZ-8-dodeceneNA 1531NA 224NA 224PheromonePheromoneZ-8-dodecenol40642-40-8#####2253PheromonePheromoneZ-8-dodecenyl acetate28079-04-1#####2251PheromonePheromone7-(diethyl amino)-4-methyl91-44-1NA 3413146RodenticideCoumarincoumarinBrodifacoum56073-10-0#####2049RodenticideCoumarinBromadiolone28772-56-7#####2135RodenticideCoumarinCoumachlor81-82-3#####NA 126RodenticideCoumarinCoumafuryl117-52-286001298RodenticideCoumarinCoumafuryl, sodium salt34490-93-286004299RodenticideCoumarinCoumarin91-64-5#####NA 102RodenticideCoumarinCoumatetralyl5836-29-3#####NA 153RodenticideCoumarinDifenacoum56073-07-5#####NA 970RodenticideCoumarinFlocoumafen90035-08-8NA 182NA 181RodenticideCoumarinPotassium warfarin2610-86-886005NA 836RodenticideCoumarinPyranocoumarinNA 1431NA 199NA 199RodenticideCoumarinWarfarin81-81-286002621RodenticideCoumarinWarfarin, sodium salt129-06-6860031184RodenticideCoumarin2-isovaleryl 1-1,3-indandione83-28-3677021435Rodenticide1,3-Indandione2-isovaleryl 1-1,3-indandione,23710-76-1677061736Rodenticide1,3-Indandionecalcium salt2-isovaleryl-1,3-indandione,53404-57-267709NA 596Rodenticide1,3-Indandionesodium saltChlorophacinone3691-35-8677071625Rodenticide1,3-IndandioneDiphacinone82-66-667701225Rodenticide1,3-IndandioneDiphacinone, sodium salt42721-99-3677051636Rodenticide1,3-IndandionePindone83-26-167703489Rodenticide1,3-IndandionePindone, calcium salt53404-72-167708NA 595Rodenticide1,3-IndandionePindone, sodium salt6120-20-3677041305Rodenticide,1,3-IndandioneBird Repellent4-HydroxymethylNA 1173NA 177NA 165Breakdown2,6-DinitroanilinependimethalinproductBenfluralin1861-40-18430153Herbicide2,6-DinitroanilineButralin33629-47-9#####1756Herbicide2,6-DinitroanilineDinitramine29091-05-2#####1683Herbicide2,6-DinitroanilineDipropalin5332#####NA 145Herbicide2,6-DinitroanilineEthalfluralin55283-68-6#####2166Herbicide2,6-DinitroanilineFluazinam79622-59-6#####3898Fungicide2,6-DinitroanilineFluchloralin33245-39-5#####1848Herbicide2,6-DinitroanilineFlumetralin62924-70-3#####5085Plant Growth2,6-DinitroanilineRegulatorIsopropalin33820-53-0#####1681Herbicide2,6-DinitroanilineN,N-Bis(2-chloroethyl)-4-26389-78-6#####NA 135N/A2,6-Dinitroanilinemethyl-2,6-dinitroanilineNitralin4726-14-137601490Herbicide2,6-DinitroanilineOryzalin19044-88-3#####1868Herbicide2,6-DinitroanilinePendimethalin40487-42-1#####1929Herbicide2,6-DinitroanilineProdiamine29091-21-2#####2236Herbicide2,6-DinitroanilineProdiamine, other relatedNA 1149NA 16892236Herbicide2,6-DinitroanilineProfluralin26399-36-0#####1897Herbicide2,6-DinitroanilineProfluralin, other relatedNA 1141NA 16791897Herbicide2,6-DinitroanilineTrifluralin1582-09-836101597Herbicide2,6-Dinitroaniline1-(3-51971-67-6#####NA 110N/ACarboxamidechlorophthalimido)cyclohexanecarboxamideAllidochlor93-71-019301114HerbicideAmideAllidochlor202-270-7NA 210NA 210HerbicideAmideAmmonium benzadox5251-79-698201NA 858HerbicideAmideBeflubutamid113614-08-7NA 230NA 230HerbicideAmideBenzadox5251-93-4#####NA 132HerbicideAmideBenzipram35256-86-1#####NA 133HerbicideAmideBromobutide74712-19-9NA 203NA 203HerbicideAmideCarboxin5234-68-4902011755FungicideCarboxamideChlorthiamid1918-13-4#####NA 139HerbicideAmideCisanilide34484-77-0#####NA 144HerbicideCarboxamideCyclafuramide34849-42-8#####NA 132FungicideCarboxamideCyprazole42089-03-2#####NA 132HerbicideAmideDimethenamid87674-68-8#####5112HerbicideAmideDiphenamid957-51-736601226HerbicideAmideEpronaz59026-08-3NA 231NA 231HerbicideAmideEtnipromid76120-02-0NA 231NA 231HerbicideAmideFenfuram24691-80-3NA 188NA 187FungicideCarboxamideFentrazamide158237-07-1NA 232NA 231HerbicideAmideFlupoxam119126-15-7NA 188NA 188HerbicideAmideFurmecyclox (Xyligen B)60568-05-0#####NA 18FungicideCarboxamideHalosafen77227-69-1NA 229NA 229HerbicideAmide, NitrophenyletherIsocarbamide30979-48-7NA 183NA 182HerbicideAmideIsoxaben82558-50-7#####2289HerbicideAmideMethfuroxam28730-17-8#####NA 949FungicideCarboxamideMetsulfovax21452-18-6NA 189NA 188FungicideCarboxamideNapropamide15299-99-7#####1728HerbicideAmideNaptalam132-66-1307022998HerbicideAmideNaptalam, sodium salt132-67-230703437HerbicideAmideNitrofurazone (not subject to59-87-0#####NA 128N/ACarboxamideFIFRA: 8709-e pm 24)Oxycarboxin5259-88-1902021434FungicideCarboxamidep-Benzoquinone61566-21-0#####NA 133N/ACarboxamidesemicarbazonePethoxamid106700-29-2NA 233NA 233HerbicideAmidePropyzamide23950-58-5#####694HerbicideAmidePropyzamide metaboliteNA 1048NA 1554093BreakdownAmideproductQuinonamid27541-88-4NA 210NA 209HerbicideAmide2-Hydroxy alachlorNA 943NA 1832602BreakdownChloroacetanilideproduct3,4,5-tribromo salicylanilide,NA 1122NA 16590833MicrobiocideAnilideother related3,5-dibromosalicylanilide2577-72-2774051256MicrobiocideAnilide5,4-dibromosalicylanilideNA 1024NA 1221071MicrobiocideAnilideAatram (propachlor with8070-76-680816NA 781HerbicideTriazine,atrazine) (019101 + 080803)ChloroacetanilideAcetochlor34256-82-1#####2349HerbicideChloroacetanilideAlachlor15972-60-890501678HerbicideChloroacetanilideBenodanil15310-01-7#####NA 154FungicideAnilideButachlor23184-66-9#####4056HerbicideChloroacetanilideButenachlor87310-56-3NA 206NA 206HerbicideChloroacetanilideClomeprop84496-56-0NA 204NA 203HerbicideAnilideCyprofuram69581-33-5NA 186NA 185FungicideAnilideCypromid2759-71-926101178HerbicideAnilideDelachlor24353-58-0#####NA 132HerbicideChloroacetanilideDiethatyl-ethyl38727-55-8#####1995HerbicideChloroacetanilideDiflufenican83164-33-4NA 184NA 183HerbicideAnilideDimethachlor50563-36-5NA 184NA 183HerbicideChloroacetanilideEtobenzanid79540-50-4NA 229NA 228HerbicideAnilideFenasulam78357-48-9NA 231NA 231HerbicideAnilideFlufenacet142459-58-3#####5293HerbicideAnilideFlufenicanNA 1568NA 234NA 234HerbicideAnilideFlutolanil66332-96-5#####2305FungicideAnilideMefenacet73250-68-7NA 189NA 188HerbicideAnilideMefluidide53780-34-0#####5082Herbicide,AnilidePlant GrowthRegulatorMefluidide, diethanolamine salt53780-36-2#####1955HerbicideAnilideMefluidide, potassium salt83601-83-6#####5083HerbicideAnilideMepronil55814-41-0NA 189NA 188FungicideAnilideMetazachlor67129-08-2NA 184NA 183HerbicideChloroacetanilideMetolachlor51218-45-2#####1996HerbicideChloroacetanilideMetolachlor, (S)87392-12-9#####5133HerbicideChloroacetanilideMonalide7287-36-7#####NA 134HerbicideAnilideNaproanilide52570-16-8NA 233NA 232HerbicideAnilideOfurace58810-48-3NA 189NA 188FungicideAnilideOxadixyl77732-09-3#####3539FungicideAnilidePerfluidone37924-13-3#####1895HerbicideAnilidePerfluidone, diethanolamineNA 991NA 6711896HerbicideAnilidesaltPretilachlor51218-49-6NA 184NA 184HerbicideChloroacetanilidePropachlor1918-16-719101511HerbicideChloroacetanilidePropanil709-98-828201503HerbicideAnilidePropisochlor86763-47-5NA 233NA 233HerbicideChloroacetanilidePrynachlor21267-72-1#####NA 138Herbicide,ChloroacetanilidePlant GrowthRegulatorPyracarbolid24691-76-7NA 210NA 209FungicideAnilideSalicylanilide87-17-277407450Fungicide,AnilideMicrobiocideSodium salicylanilide251930#####NA 145FungicideAnilideThenylchlor96491-05-3NA 229NA 229HerbicideChloroacetanilideTriclocarban101-20-227901844N/AAnilideBenzoylprop22212-56-2NA 182NA 181HerbicideArylalanineBenzoylprop ethyl22212-55-1#####NA 147HerbicideArylalanineBenzoylprop-ethyl33878-50-1NA 206NA 205HerbicideArylalanineFlamprop58667-63-3NA 188NA 187HerbicideArylalanineFlamprop-isopropyl52756-22-6#####NA 154HerbicideArylalanineFlamprop-M-isopropyl57973-67-8#####NA 154HerbicideArylalanineFlamprop-M-methyl57973-66-7#####NA 104HerbicideArylalanineFlamprop-methyl52756-25-9#####NA 154HerbicideArylalanineChlorazifop60074-25-1NA 231NA 230HerbicideAryloxyphenoxypropionic acidClodinafop114420-56-3NA 182NA 182Plant GrowthAryloxyphenoxyRegulatorpropionic acidClodinafop-propargyl105512-06-9#####NA 163Plant GrowthAryloxyphenoxyRegulatorpropionic acidClofop26129-32-8NA 207NA 206HerbicideAryloxyphenoxypropionic acidCyhalofop122008-78-0NA 204NA 203HerbicideAryloxyphenoxypropionic acidCyhalofop butyl122008-85-9NA 2155748HerbicideAryloxyphenoxypropionic acidDiclofop40843-25-2#####NA 912HerbicideAryloxyphenoxypropionic acidDiclofop-methyl51338-27-3#####2034HerbicideAryloxyphenoxypropionic acidFenoxaprop-ethyl82110-72-3NA 201NA 200HerbicideAryloxyphenoxy(stereochemistry unspecified)propionic acidFenoxaprop-P (+)71283-80-2#####5123HerbicideAryloxyphenoxypropionic acidFenoxaprop-P (+/−)66441-23-4#####2311HerbicideAryloxyphenoxypropionic acidFenoxaprop-P-ethyl113158-40-0NA 220NA 219HerbicideAryloxyphenoxypropionic acidFenthiaprop (racemic)95721-12-3NA 207NA 207HerbicideAryloxyphenoxypropionic acidFenthiaprop (unstated73519-50-3NA 218NA 217HerbicideAryloxyphenoxystereochemistry)propionic acidFenthiaprop-ethyl (racemic)93921-16-5NA 218NA 217HerbicideAryloxyphenoxypropionic acidFenthiaprop-ethyl (unstated66441-11-0NA 218NA 217HerbicideAryloxyphenoxystereochemistry)propionic acidFluazifop69335-91-7NA 194NA 193HerbicideAryloxyphenoxypropionic acidFluazifop-butyl69806-50-4#####2186HerbicideAryloxyphenoxypropionic acidFluazifop-P-butyl79241-46-6#####NA 995HerbicideAryloxyphenoxypropionic acidFluazifop-P-butyl83066-88-0NA 228NA 228HerbicideAryloxyphenoxypropionic acidHaloxyfop (unstated69806-34-4#####NA 100HerbicideAryloxyphenoxystereochemistry)propionic acidHaloxyfop-etotyl (unstated87237-48-7NA 200NA 199HerbicideAryloxyphenoxystereochemistry)propionic acid,Glycol EtherHaloxyfop-methyl (unstated690806-40-2#####NA 19HerbicideAryloxyphenoxystereochemistry)propionic acidHaloxyfop-R72619-32-0NA 191NA 190HerbicideAryloxyphenoxypropionic acidPropaquizafop111479-05-1NA 185NA 184HerbicideAryloxyphenoxypropionic acidQuizalofop76578-12-6NA 190NA 189HerbicideAryloxyphenoxypropionic acidQuizalofop-ethyl76578-14-8#####2226HerbicideAryloxyphenoxypropionic acidQuizalofop-P94051-08-8NA 185NA 184HerbicideAryloxyphenoxypropionic acidQuizalofop-P-ethyl100646-51-3NA 212NA 211HerbicideAryloxyphenoxypropionic acidQuizalofop-p-tefuryl119738-06-6NA 202NA 202HerbicideAryloxyphenoxypropionic acidTrifop58594-744NA 234NA 233HerbicideAryloxyphenoxypropionic acid2,5-Dichlorobenzoic acid50-79-3NA 224NA 224FungicideBenzoic acid2,5-Dichlorobenzoic acid2905-69-3NA 224NA 224FungicideBenzoic acidmethyl ester3,5-dichlorobenzoic acid51-36-5NA 1564066N/ABenzoic acid4′-hydroxy-m-phenoxy benzoic35065-12-4NA 1762609Fungicide,Benzoic acidacidMicrobiocide4-hydroxy benzoic acid99-96-7NA 200NA 199N/ABenzoic acid5-hydroxy-dicambaNA 840NA 1564065Herbicide,Benzoic acidBreakdownproductButyl paraben94-26-861205NA 496Fungicide,Benzoic acidMicrobiocideChloramben133-90-4299012184HerbicideBenzoic acidChloramben, ammonium salt1076-46-629902831HerbicideBenzoic acidChloramben, ammonium salt,NA 1121NA 16590831HerbicideBenzoic acidother relatedDicamba1918-00-929801200HerbicideBenzoic acidDicamba with 2,4-D8068-77-729807NA 219HerbicideBenzoic acidDicamba with 2,4-D & Silvex8073-53-829808NA 220HerbicideBenzoic acidDicamba, aluminium saltNA 1215#####NA 170HerbicideBenzoic acidDicamba, butoxyethyl esterNA 1477NA 220NA 219HerbicideBenzoic acidDicamba, diethanolamine salt25059-78-329803780HerbicideBenzoic acidDicamba, diglycolamine salt104040-79-1#####5007HerbicideBenzoic acidDicamba, dimethylamine salt2300-66-529802849HerbicideBenzoic acidDicamba, dimethylamine salt,NA 1123NA 16590849HerbicideBenzoic acidother relatedDicamba, isopropylamine salt55871-02-8#####5098HerbicideBenzoic acidDicamba, methyl ester6597-78-0#####NA 146HerbicideBenzoic acidDicamba, monoethanolamine53404-28-7298041829HerbicideBenzoic acidsaltDicamba, monoethanolamineNA 1140NA 16791829HerbicideBenzoic acidsalt, other relatedDicamba, other relatedNA 1084NA 16190200HerbicideBenzoic acidDicamba, potassium salt10007-85-9#####5110HerbicideBenzoic acidDicamba, sodium salt1982-69-0298065057HerbicideBenzoic acidDicamba, triethanolamine salt53404-29-8298051113HerbicideBenzoic acidDichlorobenzoic acidNA 1383NA 195NA 194FungicideBenzoic acidmethylesterDiethanolamine 3-amino-2,5-53404-16-329904NA 222HerbicideBenzoic aciddichlorobenzoateDodecylamine salicylate7491-21-6393022003Insecticide,Benzoic acidFungicide,MicrobiocideEthyl paraben120-47-8612023204Fungicide,Benzoic acidMicrobiocideHomosalate118-56-9766033231Insecticide,Benzoic acidFungicide,MicrobiocideMethyl chloramben7286-84-229905NA 223HerbicideBenzoic acidMethyl paraben99-76-3612011005Fungicide,Benzoic acidMicrobiocideMethyl paraben, calcium salt40167-95-161208NA 499Fungicide,Benzoic acidMicrobiocideMethyl paraben, sodium salt5026-62-061207NA 498Fungicide,Benzoic acidMicrobiocideMonomethylammonium25182-03-029903NA 221HerbicideBenzoic acidchloramben (3-amino-2,5-dichlorobenzoic acid)Propyl paraben94-13-3612032841Fungicide,Benzoic acidMicrobiocidePropyl paraben, calcium salt83542-69-261206NA 497Fungicide,Benzoic acidMicrobiocidePropyl paraben, sodium salt35285-69-961204NA 495Fungicide,Benzoic acidMicrobiocideSalicylic acid69-72-7766021170Insecticide,Benzoic acidFungicide,MicrobiocideSodium 3-amino-2,5-1954-81-029906NA 224HerbicideBenzoic aciddichlorobenzoateTricamba2307-49-517301NA 151HerbicideBenzoic acidAnisuron2689-43-2#####NA 138HerbicideBenzoylureaDiflubenzuron35367-38-5#####1992InsecticideBenzoylureaFlucycloxuron113036-88-7#####NA 109HerbicideBenzoylureaFlucycloxuron, (E)94050-52-9NA 201NA 200HerbicideBenzoylureaFlufenoxuron101463-69-8#####NA 901InsecticideBenzoylureaHexaflumuron86479-06-3#####3899InsecticideBenzoylureaLufenuron103055-07-8NA 184NA 183InsecticideBenzoylureaNovaluron116714-46-6NA 226NA 226HerbicideBenzoylureaPhenobenzuron449583#####NA 133HerbicideBenzoylureaTeflubenzuron83121-18-0#####NA 33InsecticideBenzoylureaTriflumuron64628-44-0#####2961InsecticideBenzoylureaDiethamquat chlorideNA 1567NA 231NA 231HerbicideBipyridyliumDiquat bistribromide27041-82-3#####NA 146HerbicideBipyridyliumDiquat dibromide85-00-732201229Herbicide,BipyridyliumDessicantDiquat ion2764-72-932202NA 294N/ABipyridyliumMonolinuron with paraquat69312-67-0#####NA 119HerbicideUrea, BipyridyliumdichlorideMorfamquat7411-47-4#####NA 135N/ABipyridyliumMorfamquat7411-47-4NA 201NA 200HerbicideBipyridyliumMorfamquat chloride4636-83-3NA 212NA 212HerbicideBipyridyliumParaquat4685-14-761603NA 500HerbicideBipyridyliumParaquat bis(methylsulfate)2074-50-261602458HerbicideBipyridyliumParaquat bistribromide27041-84-5#####NA 159HerbicideBipyridyliumParaquat dichloride1910-42-5616011601HerbicideBipyridyliumPriglone (diquat dibromide78403-23-332203NA 295N/ABipyridyliumw/paraquat ion)1,3-Dimethyl-1,1,3,3-22232-20-834601NA 303N/ABis-Carbamatedisiloxanetetrol-1,3-bis(dimethylthiocarbamate)Desmedipham13684-56-5#####1748HerbicideBis-CarbamateDimethyl (4-methyl-1,3-51543-98-7#####NA 888FungicideBis-Carbamatephenylenebis(iminocarbonyl-1H-benzimidazole-1,2-diyl))biscarbamatePhenisopham57375-63-0NA 209NA 208HerbicideBis-CarbamatePhenmedipham13684-63-498701675HerbicideBis-CarbamatePhenmedipham-ethyl13684-44-1#####NA 149HerbicideBis-Carbamate2-Hydroxy alachlorNA 943NA 1832602BreakdownChloroacetanilideproductAatram (propachlor with8070-76-680816NA 781HerbicideTriazine,atrazine) (019101 + 080803)ChloroacetanilideAcetochlor34256-82-1#####2349HerbicideChloroacetanilideAlachlor15972-60-890501678HerbicideChloroacetanilideButachlor23184-66-9#####4056HerbicideChloroacetanilideButenachlor87310-56-3NA 206NA 206HerbicideChloroacetanilideDelachlor24353-58-0#####NA 132HerbicideChloroacetanilideDiethatyl-ethyl38727-55-8#####1995HerbicideChloroacetanilideDimethachlor50563-36-5NA 184NA 183HerbicideChloroacetanilideMetazachlor67129-08-2NA 184NA 183HerbicideChloroacetanilideMetolachlor51218-45-2#####1996HerbicideChloroacetanilideMetolachlor, (S)87392-12-9#####5133HerbicideChloroacetanilidePretilachlor51218-49-6NA 184NA 184HerbicideChloroacetanilidePropachlor1918-16-719101511HerbicideChloroacetanilidePropisochlor86763-47-5NA 233NA 233HerbicideChloroacetanilidePrynachlor21267-72-1#####NA 138Herbicide,ChloroacetanilidePlant GrowthRegulatorThenylchlor96491-05-3NA 229NA 229HerbicideChloroacetanilide(2-Methyl-4,6-13333-87-4#####NA 161ImpurityChlorophenoxy aciddichlorophenoxy)acetic acidor ester(as impurity)2,3,6-Trichlorophenylacetic2903-64-282603NA 819HerbicideChlorophenoxy acidacidor ester2,3,6-Trichlorophenylacetic53404-91-482604NA 820HerbicideChlorophenoxy acidacid, sodium saltor ester2,4,5-T93-76-582001639HerbicideChlorophenoxy acidor ester2,4,5-T tetradecylamine salt53535-37-8820131989HerbicideChlorophenoxy acidor ester2,4,5-T, 2-ethylhexyl ester1928-47-8820631092HerbicideChlorophenoxy acidor ester2,4,5-T, alkylamine salt53535-37-882013818HerbicideChlorophenoxy acidor ester2,4,5-T, butoxyethanol ester2545-59-782053819HerbicideChlorophenoxy acidor ester, Glycol Ether2,4,5-T, butoxyethanol ester2545-59-782072NA 166HerbicideChlorophenoxy acidor ester2,4,5-T, butoxypropyl ester1928-48-982055820HerbicideChlorophenoxy acidor ester2,4,5-T, butyl ester93-79-882056822HerbicideChlorophenoxy acidor ester2,4,5-T, butyric acid93-80-1#####NA 152HerbicideChlorophenoxy acidor ester2,4,5-T, dimethylamine salt6369-97-7820191474HerbicideChlorophenoxy acidor ester2,4,5-T, dodecylamine salt53404-84-5820111988HerbicideChlorophenoxy acidor ester2,4,5-T, isooctyl ester25168-15-4NA 121851HerbicideChlorophenoxy acidor ester2,4,5-T, N-oleyl-1,3-53404-87-8820291097HerbicideChlorophenoxy acidpropylenediamine saltor ester2,4,5-T, propylene glycol butyl1928-48-982055824HerbicideChlorophenoxy acidether esteror ester2,4,5-T, triethylamine salt2008-46-082034850HerbicideChlorophenoxy acidor ester2,4,5-trichlorophenoxyacetic69462-12-082064NA 799HerbicideChlorophenoxy acidacid, 2-ethyl-4-methylpentylor esterester2,4,5-trichlorophenoxyacetic53404-85-682012NA 790HerbicideChlorophenoxy acidacid, alkyl(C13) amine saltor ester2,4,5-trichlorophenoxyacetic120-39-882051NA 795HerbicideChlorophenoxy acidacid, amyl esteror ester2,4,5-trichlorophenoxyacetic1928-58-182052NA 796HerbicideChlorophenoxy acidacid, butoxyethoxypropanolor esterester2,4,5-trichlorophenoxyacetic53404-86-782038NA 793HerbicideChlorophenoxy acidacid, diethylethanolamine saltor ester2,4,5-trichlorophenoxyacetic4938-72-182062NA 798HerbicideChlorophenoxy acidacid, isobutyl esteror ester2,4,5-trichlorophenoxyacetic93-78-782066NA 800HerbicideChlorophenoxy acidacid, isopropyl esteror ester2,4,5-trichlorophenoxyacetic55256-33-282039NA 794HerbicideChlorophenoxy acidacid, N,N-dimethyl oleyl-or esterlinoleyl amine salt2,4,5-trichlorophenoxyacetic53404-88-982037NA 792HerbicideChlorophenoxy acidacid, N,N-or esterdimethyllinoleylamine salt2,4,5-trichlorophenoxyacetic53404-89-082020NA 791HerbicideChlorophenoxy acidacid, N,N-dimethyloleylamineor estersalt2,4,5-trichlorophenoxyacetic55491-33-382077NA 803HerbicideChlorophenoxy acidacid, pentyl esteror ester2,4,5-trichlorophenoxyacetic13560-99-182004NA 789HerbicideChlorophenoxy acidacid, sodium saltor ester2,4,5-trichlorophenoxyacetic53535-32-382075NA 802HerbicideChlorophenoxy acidacid, tripropylene glycolor esterisobutyl ether ester2,4-D94-75-730001636Herbicide,Chlorophenoxy acidPlant Growthor esterRegulator2,4-D with 2,4,5-T8015-35-830077NA 259HerbicideChlorophenoxy acidor ester2,4-D, 2-ethyl-4-methylpentyl53404-37-8NA 227NA 227HerbicideChlorophenoxy acidesteror ester2,4-D, 2-ethylhexyl ester1928-43-4300631622HerbicideChlorophenoxy acidor ester2,4-D, alkanolamine salts2307-55-330005801HerbicideChlorophenoxy acid(ethanol and isopropanolor esteramines)2,4-D, alkyl (C12) amine salts2212-54-630011980HerbicideChlorophenoxy acidor ester2,4-D, alkyl (C14) amine salts28685-18-930013981HerbicideChlorophenoxy acidor ester2,4-D, butoxy ethoxy propanol1928-57-0300521255HerbicideChlorophenoxy acidesteror ester2,4-D, butoxyethanol ester1929-73-330053802HerbicideChlorophenoxy acidor ester, Glycol Ether2,4-D, butoxyethanol ester1929-73-330061NA 166HerbicideChlorophenoxy acidor ester2,4-D, butoxypropyl ester1928-45-630055803HerbicideChlorophenoxy acidor ester2,4-D, butyl ester94-80-430056804HerbicideChlorophenoxy acidor ester2,4-D, chlorocrotyl ester2971-38-2NA 228NA 227HerbicideChlorophenoxy acidor ester2,4-D, diethanolamine salt5742-19-830016805HerbicideChlorophenoxy acidor ester2,4-D, diethylamine salt20940-37-830017875HerbicideChlorophenoxy acidor ester2,4-D, dimethylamine salt2008-39-130019806HerbicideChlorophenoxy acidor ester2,4-D, dodecylamine salt2212-54-630011807HerbicideChlorophenoxy acidor ester2,4-D, heptylamine salt37102-63-9300231962HerbicideChlorophenoxy acidor ester2,4-D, isooctyl ester25168-26-730064809HerbicideChlorophenoxy acidor esterTriclopyr55335-06-3#####NA 36HerbicideChloropyridinylTriclopyr ethyl ester60825-27-6#####NA 108HerbicideChloropyridinylTriclopyr, butoxyethyl ester64700-56-7#####2170HerbicideChloropyridinyl,Glycol EtherTriclopyr, triethylamine salt57213-69-1#####2131HerbicideChloropyridinylAlloxydim55634-91-8NA 203NA 203HerbicideCyclohexenonederivativeAlloxydim sodium55635-13-7#####NA 926HerbicideCyclohexenonederivativeButroxydim138164-12-2NA 202NA 202HerbicideCyclohexenonederivativeClethodim99129-21-2#####3566HerbicideCyclohexenonederivativeCloproxydim95480-33-4NA 231NA 231HerbicideCyclohexenonederivativeCycloxydim101205-02-1NA 184NA 183HerbicideCyclohexenonederivativeSethoxydim74051-80-2#####2177HerbicideCyclohexenonederivativeTepraloxydim149979-41-9#####NA 982HerbicideCyclohexenonederivativeTralkoxydim87820-88-0#####5457HerbicideCyclohexenonederivative2,4-dinitrophenol51-28-537509221ImpurityDinitrophenolderivative2,4-dinitrophenol, sodium salt1011-73-0#####NA 161Impurity,Dinitrophenol(as impurity)Breakdownderivativeproduct2,4-Dinitrophenyl thiocyanate1594-56-5#####NA 146N/ADinitrophenolderivative2,6-dinitrophenol, sodium salt32581-06-9#####NA 161ImpurityDinitrophenol(as impurity)derivative2-Cyclohexyl-4,6-dinitrophenol317-83-937502NA 316N/ADinitrophenoldicyclohexylaminederivative3,3′-Dichloro-5,5′-dinitro-(1,1′-15595-24-1#####NA 137N/ADinitrophenolbiphenyl)-2,2′-diolderivative3,3′-Dichloro-5,5′-dinitro-(1,1′-63992-31-4#####NA 137N/ADinitrophenolbiphenyl)-2,2′-diolderivative4,6-Dinitro-2-69632-97-9#####NA 145N/ADinitrophenolcyclohexylphenol, 2-((2-derivativeaminoethyl)amino)ethanol salt4,6-Dinitro-2-69632-98-0#####NA 145N/ADinitrophenolcyclohexylphenol,derivativetriethanolamine salt5,5′-Dichloro-3,3′-dinitro-(1,1′-10331-57-4#####NA 137N/ADinitrophenolbiphenyl)-2,2′-diolderivative6,6′-Dichloro-4,4′-dinitro-(1,1′-21832-25-7#####NA 137N/ADinitrophenolbiphenyl)-2,2′-diolderivativeBinapacryl485-31-41220173HerbicideDinitrophenolderivativeDiethanolamine dinoseb (2-53404-43-637514NA 320HerbicideDinitrophenolsec-butyl-4,6-dinitrophenol)derivativeDinex131-89-537501NA 315N/ADinitrophenolderivativeDinitro cresol534-52-1375073170FungicideDinitrophenolderivativeDinitro-1-methyl heptyl phenolNA 159NA 302758N/ADinitrophenolderivativeDinitrophenol (mixed isomers)25550-58-7NA 223NA 223BreakdownDinitrophenolproduct,derivativeImpurityDinobuton973-21-7#####2526Insecticide,DinitrophenolFungicidederivativeDinocap39300-45-336001344Fungicide,DinitrophenolInsecticidederivativeDinocap, other relatedNA 1091NA 16290344Insecticide,DinitrophenolFungicidederivativeDinocton32534-96-6NA 207NA 206Insecticide,DinitrophenolFungicidederivativeDinofenate61614-62-8#####NA 146HerbicideDinitrophenolderivativeDinopenton5386-57-2#####NA 154N/ADinitrophenolderivativeDinoprop7257-41-2#####NA 138N/ADinitrophenolderivativeDinosam4097-36-337504NA 318N/ADinitrophenolderivativeDinoseb88-85-737505238Herbicide,DinitrophenolDefoliantderivativeDinoseb acetate2813-95-8NA 207NA 206HerbicideDinitrophenolderivativeDinoseb, amine salt224438737511239Herbicide,DinitrophenolDefoliantderivativeDinoseb, ammonium salt6365-83-937513240Herbicide,DinitrophenolDefoliantderivativeDinoseb, sodium salt35040-03-0375121445Herbicide,DinitrophenolDefoliantderivativeDinoseb, triethanolamine salt6420-47-937506235Herbicide,DinitrophenolDefoliantderivativeDinosulfon5386-77-6#####NA 157N/ADinitrophenolderivativeDinoterb1420-07-1#####NA 128HerbicideDinitrophenolderivativeDinoterbon6073-72-9#####NA 128HerbicideDinitrophenolderivativeDNOC, sodium salt2312-76-737508533Fungicide,DinitrophenolMicrobiocide,derivativeInsecticide,HerbicideEtinofen2544-94-7#####NA 147N/ADinitrophenolderivativeMedinoterb acetate212943NA 208NA 208HerbicideDinitrophenolderivativeMethyl 2-(1-methylheptyl)-4,6-5386-68-5#####NA 157N/ADinitrophenoldinitrophenyl carbonatederivativePremerge plus (naptalam with8075-57-830704NA 278HerbicideDinitrophenoldinoseb)derivativeSodium naptalam with sodium59915-53-630705NA 279HerbicideDinitrophenoldinosebderivativeSultropen963-22-4#####NA 146N/ADinitrophenolderivativeAcifluorfen50594-66-6#####NA 935HerbicideDiphenyl etherAcifluorfen, sodium salt62476-59-9#####2218HerbicideDiphenyl etherAclonifen74070-46-5NA 187NA 187HerbicideDiphenyl etherBifenox42576-02-3#####1953HerbicideDiphenyl etherChlomethoxyfen32861-85-1NA 185NA 185HerbicideDiphenyl etherDiofenolan63837-33-27703NA 101HerbicideDiphenyl etherEthyl acifluorfen77207-01-3#####NA 936HerbicideDiphenyl etherFluoroglycofen77501-60-1NA 181NA 180HerbicideDiphenyl etherFomesafen72178-02-0#####NA 17HerbicideDiphenyl etherFomesafen sodium108731-70-0#####5086HerbicideDiphenyl etherLactofen77501-63-4#####3538HerbicideDiphenyl etherMethyl acifluorfen50594-67-7#####NA 937HerbicideDiphenyl etherOxyfluorfen42874-03-3#####1973HerbicideDiphenyl etherBromobonil25671-46-9#####NA 134HerbicideHydroxybenzonitrileBromoxynil butyrate3861-41-4353032163HerbicideHydroxybenzonitrileBromoxynil heptanoate56634-95-8#####5036HerbicideHydroxybenzonitrileBromoxynil octanoate1689-99-235302834HerbicideHydroxybenzonitrileBromoxynil pentanoateNA 1476NA 220NA 219HerbicideHydroxybenzonitrileBromoxynil phenol1689-84-5353012429HerbicideHydroxybenzonitrileChloroxynil1891-95-8#####NA 138HerbicideHydroxybenzonitrileIoxynil1689-83-4#####2616HerbicideHydroxybenzonitrileIoxynil lithium2961-61-7#####NA 141HerbicideHydroxybenzonitrileIoxynil octanoate3861-47-0#####NA 141HerbicideHydroxybenzonitrileIoxynil sodium2961-62-8#####NA 141HerbicideHydroxybenzonitrile3-5-(1,1-Dimethylethyl)-3-78327-32-9#####NA 108AlgaecideImidazolinoneisoxazolyl-4-hydroxy-1-methyl-2-imidazolidinone3-Pyridinecarboxylic acid, 2-81334-60-3#####NA 1HerbicideImidazolinone(4,5-dihydro-4-methyl-4-(1-methylethyl)-5-oxo-1H-imidazol-2-yl)-5-methyl-, (.+−.)-Imazamethabenz81405-85-8#####2240HerbicideImidazolinoneImazamox114311-32-9#####NA 2HerbicideImidazolinoneImazapic104098-48-8NA 212NA 211HerbicideImidazolinoneImazapyr81334-34-1#####2256HerbicideImidazolinoneImazapyr, isopropylamine salt81510-83-0#####2257HerbicideImidazolinoneImazaquin81335-37-7#####2613Herbicide,ImidazolinonePlant GrowthRegulatorImazaquin, ammonium salt81335-47-9#####3006HerbicideImidazolinoneImazaquin, sodium salt81335-46-8#####5109HerbicideImidazolinoneImazethapyr81335-77-5#####2340Herbicide,ImidazolinonePlant GrowthRegulatorImazethapyr, ammonium salt101917-66-2#####2341HerbicideImidazolinonePyridine carboxylic acid, 2-104098-49-9#####5097HerbicideImidazolinone(4,5-dihydro-4-methyl-4-(1-methylethyl)-5-oxo-1H-imidazol-2-yl)-5-methyl,monoammonium saltChloreturon20782-58-5NA 231NA 230HerbicidePhenylureaDaimuron42609-52-9NA 204NA 204HerbicidePhenylureaFluothiuron33439-45-1NA 232NA 232HerbicidePhenylureaMethyldymron42609-73-4NA 205NA 204HerbicidePhenylureaTetrafluoron27954-37-6#####NA 145HerbicidePhenylureaBilanafos71048-99-2NA 202NA 201HerbicidePhosphinico aminoacidAmpropylofos16606-64-7NA 181NA 180FungicidePhosphonic acidGlyphosate1071-83-6#####2997HerbicidePhosphonoglycineGlyphosate, ammonium salt114370-14-8NA 2282319HerbicidePhosphonoglycineGlyphosate, diammonium saltNA 1566NA 2295810HerbicidePhosphonoglycineGlyphosate, isopropylamine38641-94-0#####1855HerbicidePhosphonoglycinesaltGlyphosate, monoammonium114370-14-8#####2301HerbicidePhosphonoglycinesaltGlyphosate, sodium sesqui salt70393-85-0#####2275HerbicidePhosphonoglycineGlyphosate-trimesium81591-81-3#####2327HerbicidePhosphonoglycineN,N-2439-99-8#####NA 884HerbicidePhosphonoglycineBis(phosphonomethyl)glycine6-chloropicolinic acid4684-94-069206NA 657HerbicidePyridinecarboxylicacidClopyralid1702-17-6#####5135HerbicidePyridinecarboxylicacidClopyralid copperNA 1458NA 216NA 216HerbicidePyridinecarboxylicacidClopyralid, monoethanolamine57754-85-5#####5050HerbicidePyridinecarboxylicsaltacidClopyralid, triethylamine saltNA 955#####2339HerbicidePyridinecarboxylicacidPicloram51455101593HerbicidePyridinecarboxylicacidPicloram, alkanolamine saltNA 1479NA 220NA 219HerbicidePyridinecarboxylicacidPicloram, diethanolamine salt5145NA 220NA 220HerbicidePyridinecarboxylicacidPicloram, isooctyl ester26952-20-55103835HerbicidePyridinecarboxylicacidPicloram, potassium salt2545-60-051045330HerbicidePyridinecarboxylicacidPicloram, triethylamine salt35832-11-25105NA 77HerbicidePyridinecarboxylicacidPicloram, triisopropanolamine6753-47-551021099HerbicidePyridinecarboxylicsaltacidPicolinafen137641-05-5NA 210NA 210HerbicidePyridinecarboxylicacidThiazopyr117718-60-2#####3984HerbicidePyridinecarboxylicacidAmidosulfuron120923-37-7NA 183NA 183HerbicideSulfonylureaAzimsulfuron120162-55-2#####NA 112HerbicideSulfonylureaBensulfuron99283-01-9NA 181NA 180HerbicideSulfonylureaBensulfuron methyl83055-99-6#####2263HerbicideSulfonylureaChlorimuron99283-00-8NA 204NA 203HerbicideSulfonylureaChlorimuron ethyl90982-32-4#####2458HerbicideSulfonylureaChlorsulfuron64902-72-3#####2143HerbicideSulfonylureaCinosulfuron94593-91-6NA 183NA 183HerbicideSulfonylureaCyclosulfamuron136849-15-5NA 204NA 203HerbicideSulfonylureaEthametsulfuron111353-84-5NA 212NA 212HerbicideSulfonylureaEthametsulfuron-methyl97780-06-8#####NA 43HerbicideSulfonylureaEthoxysulfuron126801-58-9NA 226NA 225HerbicideSulfonylureaFlazasulfuron104040-78-0NA 229NA 228HerbicideSulfonylureaFlupyrsulfuron150315-10-9NA 205NA 204HerbicideSulfonylureaFlupyrsulfuron-methylNA 1460NA 216NA 216HerbicideSulfonylureaFlupyrsulfuron-methyl, sodium144740-54-5NA 218NA 217HerbicideSulfonylureasaltHalosulfuron100784-20-1#####3919HerbicideSulfonylureaImazosulfuron122548-33-8NA 229NA 229HerbicideSulfonylureaIodosulfuron methyl185119-76-0NA 212NA 211HerbicideSulfonylureaIodosulfuron methyl, sodium144550-36-7NA 212NA 211HerbicideSulfonylureasaltMesosulfuron-methyl208465-21-8#####NA 993HerbicideSulfonylureaMetsulfuron5585-64-8NA 183NA 182HerbicideSulfonylureaMetsulfuron-methyl74223-64-6#####2222HerbicideSulfonylureaNicosulfuron111991-09-4#####3829HerbicideSulfonylureaOxasulfuron144651-06-9#####NA 991HerbicideSulfonylureaPrimisulfuron-methyl86209-51-0#####5103HerbicideSulfonylureaProsulfuron94125-34-5#####5115HerbicideSulfonylureaPyrazosulfuron98389-04-9NA 205NA 205HerbicideSulfonylureaPyrazosulfuron-ethyl93697-74-6NA 218NA 217HerbicideSulfonylureaRimsulfuron122931-48-0#####3835HerbicideSulfonylureaSulfometuron74223-56-6NA 206NA 205HerbicideSulfonylureaSulfometuron methyl74222-97-2#####2149HerbicideSulfonylureaSulfosulfuron141776-32-1856015136HerbicideSulfonylureaThifensulfuron79277-67-1NA 183NA 182HerbicideSulfonylureaThifensulfuron-methyl79277-27-3#####2237HerbicideSulfonylureaTriasulfuron82097-50-5#####5100HerbicideSulfonylureaTribenuron106040-48-6NA 206NA 205HerbicideSulfonylureaTribenuron methyl101200-48-0#####2338HerbicideSulfonylureaTriflusulfuron-methyl126535-15-7#####3875HerbicideSulfonylureaTritosulfuron142469-14-5NA 234NA 234HerbicideSulfonylureaButylate2008-41-541405565HerbicideThiocarbamateCalcium thylenebis5895-18-114501NA 139MicrobiocideDithiocarbamate(dithiocarbamate)Cufraneb11096-18-7NA 181NA 180FungicideDithiocarbamateCycloate1134-23-241301516HerbicideThiocarbamateDiammonium60731314502NA 140MicrobiocideDithiocarbamateethylenebis(dithiocarbamate)Dimepiperate61432-55-1NA 186NA 185HerbicideThiocarbamateEPTC759-94-441401264HerbicideThiocarbamateEsprocarb85785-20-2NA 203NA 202HerbicideThiocarbamateEthiolate2941-55-1#####1793HerbicideThiocarbamateFenothiocarb62850-32-2NA 188NA 187InsecticideThiocarbamateFerbam14484-64-134801288FungicideDithiocarbamateFerric nitroso dimethyl83542-83-0#####NA 149MicrobiocideDithiocarbamatedithiocarbamateFurathiocarb65907-30-4NA 176NA 52InsecticideThiocarbamateIsopolinate3134-70-1NA 232NA 232HerbicideThiocarbamateMancopper53988-93-5NA 181NA 180FungicideDithiocarbamateMancozeb223310014504211FungicideDithiocarbamate,Inorganic-ZincManeb12427-38-214505369FungicideDithiocarbamateManeb and nickel sulfate8005-46-7#####NA 158FungicideDithiocarbamate,hexahydrate (014505 + 050505)Inorganic-NickelManganous15339-36-334802NA 304FungicideDithiocarbamatedimethyldithiocarbamateMercuric dimethyl15415-64-234808709MicrobiocideInorganic-Mercury,dithiocarbamateHeavy metal,DithiocarbamateMetam sodium, dihydrate137-42-839003NA 163Fumigant,DithiocarbamateFungicide,Microbiocide,Algaecide,NematicideMetam-sodium6734-80-139003616Fumigant,DithiocarbamateHerbicide,Fungicide,Microbiocide,Algaecide,NematicideMethasulfocarb66952-49-6NA 202NA 201Fungicide,ThiocarbamatePlant GrowthRegulatorMethiobencarb18357-78-3NA 232NA 232HerbicideThiocarbamateMetiram9006-42-214601493FungicideDithiocarbamate,Inorganic-ZincMolinate2212-67-141402449HerbicideThiocarbamateMolinate sulfoxideNA 1052NA 1564080BreakdownThiocarbamateproductMorpholinomethyl31848-11-0#####NA 158MicrobiocideDithiocarbamatedimethyldithiocarbamateNabam142-59-614503417Fungicide,DithiocarbamateHerbicideOrbencarb34622-58-7NA 189NA 188HerbicideThiocarbamatePebulate1114-71-241403590HerbicideThiocarbamatePhenylmercuric32407-99-166008NA 555Microbiocide,Organomercury,dimethyldithiocarbamateFungicideDithiocarbamate,Heavy metalPotassium ammonium22221-14-314507NA 141MicrobiocideDithiocarbanaateethylenebis(dithiocarbamate)Potassium dimethyl dithiocarbamate128-03-0348031934MicrobiocideDithiocarbamatePotassium N-hydroxymethyl-51026-28-9#####1824N/ADithiocarbamateN-methyldithio carbamatePotassium N-methyldithiocarbamate137-41-739002970Fumigant,DithiocarbamateFungicide,Microbiocide,Algaecide,NematicidePropineb12071-83-9#####NA 155Fungicide,Dithiocarbamate,MicrobiocideInorganic-ZincProsulfocarb52888-80-9NA 185NA 184HerbicideThiocarbamateProthiocarb19622-08-3NA 183NA 182FungicideThiocarbamateProthiocarb hydrochloride19622-19-6NA 200NA 199FungicideThiocarbamatePyributicarb88678-67-5NA 229NA 229HerbicideThiocarbamateS-tert-Butyl2212-63-7#####NA 128HerbicideThiocarbamatedipropylthiocarbamateSodium dimethyl dithiocarbamate128-04-134804548FungicideDithiocarbamateSulfallate95-06-739001115HerbicideDithiocarbamateTert-butyl dimethyl trithioperoxycarbamate3304-97-0348071383RodentDithiocarbamateRepellentTert-NA 1130NA 16691383N/ADithiocarbamatebutyldimethyltrithioperoxycarbamate,other relatedThiobencarb28249-77-6#####1933HerbicideThiocarbamateThiobencarb sulfoxideNA 1042NA 1392937BreakdownThiocarbamateproductThiodicarb59669-26-0#####2202Molluscicide,ThiocarbamateInsecticideThiram137-26-879801589FungicideDithiocarbamateThiram and NAD and IBA and75497-92-656011NA 463Fungicide,Dithiocarbamate2-methyl-1-Plant Growthnaphthaleneacetamide and 2-Regulatormethyl-1-naphthaleneaceticacidTiocarbazil36756-79-3#####NA 911HerbicideThiocarbamateTriallate2303-17-57880249HerbicideThiocarbamateTricopper dichloride7076-63-3#####NA 152MicrobiocideDithiocarbamate,dimethyldithiocarbamateInorganic-CopperVernolate1929-77-7414041987HerbicideThiocarbamateZineb12122-67-714506627FungicideDithiocarbamate,Inorganic-ZincZineb-ethylene thiuramNA 1465NA 217NA 216FungicideDithiocarbamate,disulfide adductInorganic-ZincZiram137-30-434805629Fungicide,Dithiocarbamate,Microbiocide,Inorganic-ZincDog and CatRepellentZiram, cyclohexylamine16509-79-8348061328Dog and CatDithiocarbamate,complexRepellent,Inorganic-ZincFungicide1,3,5-Triethylhexahydro-s-7779-27-382901NA 823FungicideTriazinetriazine2-(Diethylamino)-4-3004-70-480812NA 780N/ATriazine(isopropylamino)-6-methoxy-s-triazine2-chloro-4-29450-57-5#####NA 135N/ATriazine((hydroxymethyl)amino)-6-(isopropylamino)-s-triazine3-(chloromethyl)-4-ketobenz-24310-41-6#####NA 162ImpurityTriazine1,2,3-triazine (as impurity)3-(Hydroxymethyl)-4-24310-40-5#####NA 162ImpurityTriazineketobenz-1,2,3-triazine (asimpurity)Aatram (propachlor with8070-76-680816NA 781HerbicideTriazine,atrazine) (019101 + 080803)ChloroacetanilideAmetryne834-12-88080118HerbicideTriazineAmetryne, other relatedNA 1071NA 16090018HerbicideTriazineAnilazine101-05-380811256FungicideTriazineAtraton1610-17-9808024050HerbicideTriazineAtrazine1912-24-98080345HerbicideTriazineAtrazine dealkylatedNA 1059NA 1574052BreakdownTriazineproductAtrazine, other relatedNA 1072NA 16090045HerbicideTriazineAziprotryne4658-28-0#####NA 130HerbicideTriazineChlorazine580-48-380806NA 777N/ATriazineCyanatryn21689-84-9NA 230NA 229HerbicideTriazineCyanazine21725-46-2#####1640HerbicideTriazineCyanazine acidNA 1328NA 178NA 178BreakdownTriazineproductCyanazine amideNA 1170NA 176NA 164BreakdownTriazineproductCyanazine, other relatedNA 1133NA 16691640HerbicideTriazineCyanuric acid108-80-5814022138Microbiocide,TriazineWaterTreatmentCyanuric acid, monosodium2624-17-1NA 1221031Microbiocide,TriazinesaltWaterTreatmentCybutryne28159-98-0#####4033MicrobiocideTriazineCyprazine22936-86-3#####1701HerbicideTriazineCyromazine66215-27-8#####2286InsecticideTriazineDeethyl ametryneNA 1168NA 176NA 164BreakdownTriazineproductDeethyl hydroxyatrazineNA 1330NA 179NA 178BreakdownTriazineproductDeethyl-atrazineNA 1058NA 1574051BreakdownTriazineproductDeethyl-simazineNA 1047NA 1544096BreakdownTriazineproductDeethylhydroxysimazineNA 1064NA 1595031BreakdownTriazineproductDeisopropyl atrazineNA 1169NA 176NA 164BreakdownTriazineproductDeisopropyl hydroxyatrazineNA 1331NA 179NA 178BreakdownTriazineproductDeisopropyl prometrynNA 1334NA 179NA 179BreakdownTriazineproductDesamino-metribuzinNA 1473NA 219NA 219BreakdownTriazineproductDesmetryne1014-69-380810NA 779HerbicideTriazineDiaminochlorotriazineNA 856NA 1595028BreakdownTriazineproductDiaminohydroxytriazineNA 857NA 1595032BreakdownTriazineproductDichloro-s-triazinetrione2782-57-281401204Microbiocide,TriazineWaterTreatmentDichloroisocyanuric acid,2244-21-5814032Microbiocide,Triazinepotassium saltWaterTreatmentDidealkyl atrazineNA 1329NA 178NA 178BreakdownTriazineproductDidealkyl hydroxyatrazineNA 1332NA 179NA 178BreakdownTriazineproductDiketo-desamino-metribuzinNA 1475NA 219NA 219BreakdownTriazineproductDiketo-metribuzinNA 1474NA 219NA 219BreakdownTriazineproductDimethametryn22936-75-0808152287HerbicideTriazineDipropetryn4147-51-7#####2532HerbicideTriazineEglinazine6616-80-4NA 207NA 207HerbicideTriazineEglinazine-ethyl6616-80-4NA 218NA 217HerbicideTriazineEthiozin (ebuzin/tycor)64529-56-2#####NA 15N/ATriazineHexahydro-1,3,5-triethyl-S-108-74-7NA 1251670HerbicideTriazinetriazineHexahydro-1,3,5-tris (2-1028251833011171MicrobiocideTriazinehydroxyethyl)-s-triazineHexahydro-1,3,5-tris(2-25254-50-6#####1915N/ATriazinehydroxypropyl)-s-triazineHexahydro-1,3,5-tris(3-751061#####NA 127N/ATriazinemethoxypropyl)-1,3,5-triazineHexazinone51235-04-2#####1871HerbicideTriazineHydroxyatrazine2163-68-0NA 178NA 178BreakdownTriazineproductIpazin1912-25-0#####NA 130N/ATriazineIsomethiozin57052-04-7#####NA 875N/ATriazineMetamitron41394-05-2NA 1352672HerbicideTriazineMethometon1771-07-9#####NA 156N/ATriazineMethoprotryne841-06-5#####NA 154HerbicideTriazineMetribuzin21087-64-9#####1692HerbicideTriazineMetribuzin-DANA 1053NA 1564079BreakdownTriazineproductMono (trichloro) tetra30622-37-881406856Microbiocide,Triazine(monopotassium dichloro)Waterpenta-s-triazineTreatmentMPMT845-52-3827012695N/ATriazinePotassium 1,3-dichloro-2,4,6-NA 173NA 3461650N/ATriazinetrioxo hexahydro-s-triazinePrefox (cyprazine with8071-40-7#####NA 886HerbicideTriazineethiolate)Procyanazine32889-48-8#####NA 908HerbicideTriazineProglinazine68228-20-6NA 209NA 209HerbicideTriazineProglinazine-ethyl68228-18-2NA 218NA 218HerbicideTriazinePrometon1610-18-080804499HerbicideTriazinePrometryn7287-19-680805502HerbicideTriazinePropazine139-40-280808504HerbicideTriazinePymetrozine123312-89-0#####5232InsecticideTriazineSebuthylazine7286-69-3#####NA 127N/ATriazineSecbumeton26259-45-0#####2849HerbicideTriazineSimazine122-34-980807531HerbicideTriazineSimetone673-04-1#####3532HerbicideTriazineSimetryn1014-70-6#####4097N/ATriazineSodium dichloro-s-2893-78-981404205Microbiocide,TriazinetriazinetrioneWaterTreatmentSodium dichloro-s-51580-86-0814071818Microbiocide,Triazinetriazinetrione dihydrateWaterTreatmentSym-triazine108-80-581402893Microbiocide,TriazineWaterTreatmentTerbumeton33693-04-8NA 190NA 189HerbicideTriazineTerbuthylazine5915-41-3808143004Algaecide,TriazineHerbicide,MicrobiocideTerbutryn886-50-0808131691HerbicideTriazineTerbutryn, other relatedNA 1136NA 16791691HerbicideTriazineTriaziflam131475-57-5NA 234NA 233HerbicideTriazineTrichloro melamine2107336771011023MicrobiocideTriazineTrichloro-s-triazinetrione87-90-181405407Microbiocide,TriazineWaterTreatmentTrietazine1912-26-180809NA 778HerbicideTriazine1,3-Diphenyl urea102-07-8NA 186NA 185Plant GrowthUreaRegulator3,4-Dichloromethylphenyl ureaNA 1335NA 179NA 179BreakdownUreaproduct3,4-Dichlorophenyl urea154536NA 179NA 179BreakdownUreaproduct3-(Trifluoromethyl)phenyl urea13114-87-9NA 179NA 178BreakdownUreaproductAmidosulfuron120923-37-7NA 183NA 183HerbicideSulfonylureaAnisuron2689-43-2#####NA 138HerbicideBenzoylureaAzimsulfuron120162-55-2#####NA 112HerbicideSulfonylureaBensulfuron99283-01-9NA 181NA 180HerbicideSulfonylureaBensulfuron methyl83055-99-6#####2263HerbicideSulfonylureaBentaluronNA 1405NA 197NA 197FungicideUreaBenzthiazuron1929-88-0#####NA 133HerbicideUreaButhiuron30043-55-1NA 230NA 230HerbicideUreaButuron3766-60-7#####NA 119HerbicideUreaChlorbromuron13360-45-7907011733HerbicideUreaChloreturon20782-58-5NA 231NA 230HerbicidePhenylureaChlorimuron99283-00-8NA 204NA 203HerbicideSulfonylureaChlorimuron ethyl90982-32-4#####2458HerbicideSulfonylureaChlorotoluron15545-48-9#####NA 122HerbicideUreaChloroxuron1982-47-425501576HerbicideUreaChlorsulfuron64902-72-3#####2143HerbicideSulfonylureaCinosulfuron94593-91-6NA 183NA 183HerbicideSulfonylureaCumyluron99485-76-4NA 228NA 228HerbicideUreaCyclosulfamuron136849-15-5NA 204NA 203HerbicideSulfonylureaCycluron2163-69-135504NA 306HerbicideUreaDaimuron42609-52-9NA 204NA 204HerbicidePhenylureaDemethylfluometuronNA 1333NA 179NA 178BreakdownUreaproductDichloral urea116-52-9#####NA 115HerbicideUreaDifenoxuron14214-32-5#####NA 156HerbicideUreaDiflubenzuron35367-38-5#####1992InsecticideBenzoylureaDimefuron34205-21-5NA 186NA 185HerbicideUreaDiuron330-54-135505231HerbicideUreaEthametsulfuron111353-84-5NA 212NA 212HerbicideSulfonylureaEthametsulfuron-methyl97780-06-8#####NA 43HerbicideSulfonylureaEthidimuron30043-49-3#####NA 994HerbicideUreaEthoxysulfuron126801-58-9NA 226NA 225HerbicideSulfonylureaFenuron101-42-8355074072HerbicideUreaFenuron trichloroacetate4482-55-7355085035HerbicideUreaFlazasulfuron104040-78-0NA 229NA 228HerbicideSulfonylureaFlucycloxuron113036-88-7#####NA 109HerbicideBenzoylureaFlucycloxuron, (E)94050-52-9NA 201NA 200HerbicideBenzoylureaFlufenoxuron101463-69-8#####NA 901InsecticideBenzoylureaFluometuron2164-17-235503166HerbicideUreaFluothiuron33439-45-1NA 232NA 232HerbicidePhenylureaFlupyrsulfuron150315-10-9NA 205NA 204HerbicideSulfonylureaFlupyrsulfuron-methylNA 1460NA 216NA 216HerbicideSulfonylureaFlupyrsulfuron-methyl, sodium144740-54-5NA 218NA 217HerbicideSulfonylureasaltForchlorfenuron68157-60-8#####5557Plant GrowthUreaRegulatorHalosulfuron100784-20-1#####3919HerbicideSulfonylureaHexaflumuron86479-06-3#####3899InsecticideBenzoylureaImazosulfuron122548-33-8NA 229NA 229HerbicideSulfonylureaIodosulfuron methyl185119-76-0NA 212NA 211HerbicideSulfonylureaIodosulfuron methyl, sodium144550-36-7NA 212NA 211HerbicideSulfonylureasaltIsononuron28805-78-9#####NA 151HerbicideUreaIsoproturon34123-59-6#####NA 155HerbicideUreaIsouron55861-78-4#####NA 101HerbicideUreaLinuron330-55-235506361HerbicideUreaLufenuron103055-07-8NA 184NA 183InsecticideBenzoylureaMesosulfuron-methyl208465-21-8#####NA 993HerbicideSulfonylureaMethabenzthiazuron18691-97-9#####NA 133HerbicideUreaMethiuron21540-35-2#####NA 145HerbicideUreaMethyldymron42609-73-4NA 205NA 204HerbicidePhenylureaMetobenzuron111578-32-6#####NA 37HerbicideUreaMetobromuron3060-89-735901NA 313HerbicideUreaMetoxuron19937-59-8#####NA 135HerbicideUreaMetsulfuron5585-64-8NA 183NA 182HerbicideSulfonylureaMetsulfuron-methyl74223-64-6#####2222HerbicideSulfonylureaMonisouron55807-46-0NA 233NA 232HerbicideUreaMonolinuron1746-81-2#####NA 119HerbicideUreaMonolinuron with paraquat69312-67-0#####NA 119HerbicideUrea, BipyridyliumdichlorideMonuron150-68-535501408HerbicideUreaMonuron-TCA140-41-035502409HerbicideUreaNeburon555-37-312001424HerbicideUreaNicosulfuron111991-09-4#####3829HerbicideSulfonylureaNorea18530-56-835801435HerbicideUreaNorea (stereochemistry2163-79-3NA 201NA 200HerbicideUreaunspecified)Norea, other relatedNA 1096NA 16390435HerbicideUreaNovaluron116714-46-6NA 226NA 226HerbicideBenzoylureaOxasulfuron144651-06-9#####NA 991HerbicideSulfonylureaParafluron7159-99-135510NA 307HerbicideUreaPencycuron66063-05-6#####NA 103FungicideUreaPenfluron35367-31-8#####NA 100HerbicideUreaPhenobenzuron449583#####NA 133HerbicideBenzoylureaPrimisulfuron-methyl86209-51-0#####5103HerbicideSulfonylureaProsulfuron94125-34-5#####5115HerbicideSulfonylureaPyrazosulfuron98389-04-9NA 205NA 205HerbicideSulfonylureaPyrazosulfuron-ethyl93697-74-6NA 218NA 217HerbicideSulfonylureaRimsulfuron122931-48-0#####3835HerbicideSulfonylureaSiduron1982-49-635509603HerbicideUreaSulfometuron74223-56-6NA 206NA 205HerbicideSulfonylureaSulfometuron methyl74222-97-2#####2149HerbicideSulfonylureaSulfosulfuron141776-32-1856015136HerbicideSulfonylureaTebuthiuron34014-18-1#####1810HerbicideUreaTeflubenzuron83121-18-0#####NA 33InsecticideBenzoylureaTetrafluoron27954-37-6#####NA 145HerbicidePhenylureaThiazafluron25366-23-8NA 190NA 189HerbicideUreaThidiazuron51707-55-2#####2162Defoliant, PlantUreaGrowthRegulatorThifensulfuron79277-67-1NA 183NA 182HerbicideSulfonylureaThifensulfuron-methyl79277-27-3#####2237HerbicideSulfonylureaTriasulfuron82097-50-5#####5100HerbicideSulfonylureaTribenuron106040-48-6NA 206NA 205HerbicideSulfonylureaTribenuron methyl101200-48-0#####2338HerbicideSulfonylureaTriflumuron64628-44-0#####2961InsecticideBenzoylureaTriflusulfuron-methyl126535-15-7#####3875HerbicideSulfonylureaTrimeturon3050-27-9#####NA 121HerbicideUreaTritosulfuron142469-14-5NA 234NA 234HerbicideSulfonylureaBromacil314-40-91230183HerbicideUracilBromacil, dimethylamine salt69484-13-512304840HerbicideUracilBromacil, lithium salt53404-19-6123021573HerbicideUracilBromacil, sodium salt69484-12-412303842HerbicideUracilButafenacil134605-64-4#####NA 992HerbicideUracilFlupropacil120890-70-2NA 229NA 229HerbicideUracilIsocil314-42-111801NA 119HerbicideUracilLenacil95177#####NA 155HerbicideUracilTerbacil5902-51-212701532HerbicideUracil2-Hydroxy alachlorNA 943NA 1832602BreakdownChloroacetanilideproduct3,4,5-tribromo salicylanilide,NA 1122NA 16590833MicrobiocideAnilideother related3,5-dibromosalicylanilide2577-72-2774051256MicrobiocideAnilide5,4-dibromosalicylanilideNA 1024NA 1221071MicrobiocideAnilideAatram (propachlor with8070-76-680816NA 781HerbicideTriazine,atrazine) (019101 + 080803)ChloroacetanilideAcetochlor34256-82-1#####2349HerbicideChloroacetanilideAlachlor15972-60-890501678HerbicideChloroacetanilideBenodanil15310-01-7#####NA 154FungicideAnilideButachlor23184-66-9#####4056HerbicideChloroacetanilideButenachlor87310-56-3NA 206NA 206HerbicideChloroacetanilideClomeprop84496-56-0NA 204NA 203HerbicideAnilideCyprofuram69581-33-5NA 186NA 185FungicideAnilideCypromid2759-71-926101178HerbicideAnilideDelachlor24353-58-0#####NA 132HerbicideChloroacetanilideDiethatyl-ethyl38727-55-8#####1995HerbicideChloroacetanilideDiflufenican83164-33-4NA 184NA 183HerbicideAnilideDimethachlor50563-36-5NA 184NA 183HerbicideChloroacetanilideEtobenzanid79540-50-4NA 229NA 228HerbicideAnilideFenasulam78357-48-9NA 231NA 231HerbicideAnilideFlufenacet142459-58-3#####5293HerbicideAnilideFlufenicanNA 1568NA 234NA 234HerbicideAnilideFlutolanil66332-96-5#####2305FungicideAnilideMefenacet73250-68-7NA 189NA 188HerbicideAnilideMefluidide53780-34-0#####5082Herbicide,AnilidePlant GrowthRegulatorMefluidide, diethanolamine salt53780-36-2#####1955HerbicideAnilideMefluidide, potassium salt83601-83-6#####5083HerbicideAnilideMepronil55814-41-0NA 189NA 188FungicideAnilideMetazachlor67129-08-2NA 184NA 183HerbicideChloroacetanilideMetolachlor51218-45-2#####1996HerbicideChloroacetanilideMetolachlor, (S)87392-12-9#####5133HerbicideChloroacetanilideMonalide7287-36-7#####NA 134HerbicideAnilideNaproanilide52570-16-8NA 233NA 232HerbicideAnilideOfurace58810-48-3NA 189NA 188FungicideAnilideOxadixyl77732-09-3#####3539FungicideAnilidePerfluidone37924-13-3#####1895HerbicideAnilidePerfluidone, diethanolamineNA 991NA 6711896HerbicideAnilidesaltPretilachlor51218-49-6NA 184NA 184HerbicideChloroacetanilidePropachlor1918-16-719101511HerbicideChloroacetanilidePropanil709-98-828201503HerbicideAnilidePropisochlor86763-47-5NA 233NA 233HerbicideChloroacetanilidePrynachlor21267-72-1#####NA 138Herbicide,ChloroacetanilidePlant GrowthRegulatorPyracarbolid24691-76-7NA 210NA 209FungicideAnilideSalicylanilide87-17-277407450Fungicide,AnilideMicrobiocideSodium salicylanilide251930#####NA 145FungicideAnilideThenylchlor96491-05-3NA 229NA 229HerbicideChloroacetanilideTriclocarban101-20-227901844N/AAnilide1,2,4-triazole288-88-0NA 9683560N/AAzole1H-benzo triazole95-14-7NA 4932418N/AAzole2,2′-Dithiobisbenzothiazole120-78-59202NA 109Fungicide,MercaptobenzothiazoleMicrobiocide,Insecticide2-(2′-hydroxy-5-methyl2440-22-4NA 1032607FungicideAzolephenyl)-benzotriazole2-(dithiocyanomethylthio)-NA 1346NA 192NA 191FungicideMercaptobenzothiazolebenzothiazole2-79910-32-0#####NA 925MicrobiocideMercaptobenzothiazole(thiocyanomethylthio)benzothiazolewith 2′-hydroxyethyl-2,3-dibromopropionate2-EEEBC62732-91-6#####1983FungicideBenzimidazole2-Mercaptobenzothiazole149-30-451701556Fungicide,MercaptobenzothiazoleMicrobiocide2-Mercaptobenzothiazole, 1-5468-43-951702NA 423Fungicide,Mercaptobenzothiazole(hydroxyethyl)pyridinium saltMicrobiocide2-Mercaptobenzothiazole,53404-53-851708NA 426Fungicide,Mercaptobenzothiazoleferric saltMicrobiocide2-Mercaptobenzothiazole,53404-58-39201NA 108Fungicide,Mercaptobenzothiazolemanganese saltMicrobiocide,Insecticide2-Mercaptobenzothiazole,5902-85-251706NA 424Fungicide,Mercaptobenzothiazolemonoethanolammonium saltMicrobiocide2-Mercaptobenzothiazole,7778-70-351707NA 425Fungicide,Mercaptobenzothiazolepotassium saltMicrobiocide2-Mercaptobenzothiazole,2492-26-4517043064Microbiocide,Mercaptobenzothiazolesodium saltFungicide2-Mercaptobenzothiazole,2492-26-451704613Fungicide,Mercaptobenzothiazolesodium saltMicrobiocide2-Mercaptobenzothiazole, zinc155-04-4517051449Fungicide,Mercaptobenzothiazole,saltMicrobiocideInorganic-Zinc5-Chloro-2-5331-91-9NA 200NA 199N/AMercaptobenzothiazolemercaptobenzothiazole5-Chloro-2-5406-97-3517031238MicrobiocideMercaptobenzothiazolemercaptobenzothiazole, laurylpyridinium salt5-Chloro-2-5406-97-3NA 4211597Microbiocide,Mercaptobenzothiazolemercaptobenzothiazole, laurylFungicidepyridinium salt5-Chloro-2-53404-93-651709NA 427Microbiocide,Mercaptobenzothiazole,mercaptobenzothiazole, zincFungicideInorganic-ZincsaltAzaconazole60207-31-0#####NA 105Insecticide,AzoleFungicideBenomyl17804-35-2991011552FungicideBenzimidazoleBitertanol55179-31-2#####NA 959FungicideAzoleBromuconazole116255-48-2#####NA 8FungicideAzoleCarbendazim10605-21-7#####2176FungicideBenzimidazoleCarbendazim hydrochloride37574-18-8#####NA 121FungicideBenzimidazoleCarbendazim phosphate52316-55-9991021974FungicideBenzimidazoleCGA-6425160207-93-4#####2452FungicideAzoleChlorfenapyr122453-73-0#####3938InsecticidePyrazoleChlorflurazole3615-21-2#####NA 139N/ABenzimidazoleCyazofamid120116-88-3NA 216NA 215FungicideAzoleCypendazole28559-00-4#####NA 156N/ABenzimidazoleCyproconazole94361-06-5#####5105FungicideAzoleDifenoconazole119446-68-3#####5024FungicideAzoleDiniconazole83657-18-5#####2500FungicideAzoleDiniconazole (stereochemistry83657-24-3NA 200NA 200FungicideAzoleunspecified)Fenapanil61019-78-1#####2083FungicideAzoleFenbuconazole114369-43-6#####3905FungicideAzoleFluotrimazole31251-03-3NA 207NA 207FungicideAzoleFluquinconazole136426-54-5NA 184NA 183FungicideAzoleFlusilazole85509-19-9#####2278FungicideAzoleFlutriafol76674-21-0#####NA 107FungicideAzoleFuberidazole3878-19-1#####NA 150FungicideBenzimidazoleFurconazole112839-33-5NA 196NA 196FungicideAzoleFurconazole-cis112839-32-4NA 208NA 207FungicideAzoleHexaconazole79983-71-4#####NA 23FungicideAzoleImazalil35554-44-0#####2084FungicideAzoleImazalil sulfate58594-72-2#####NA 921FungicideAzoleImibenconazole86598-92-7NA 205NA 204FungicideAzoleIsoxachlortole141112-06-3NA 232NA 232HerbicideCyclopropylisoxazoleMetconazole125116-23-6#####NA 101FungicideAzoleMetronidazole443-48-1#####2208MicrobiocideAzoleMyclobutanil88671-89-0#####2245FungicideAzoleNaphthyl triazole stilbeneNA 742NA 1352698N/AAzolemonosulfonatePaclobutrazol76738-62-0#####2259Plant GrowthAzoleRegulatorPenconazole66246-88-6#####NA 109FungicideAzoleProchloraz67747-09-5#####NA 29FungicideAzoleProchloraz - manganese75747-77-2#####NA 104FungicideAzolecomplex (4:1)Prochloraz zinc complexNA 1555NA 226NA 226FungicideAzolePropiconazole60207-90-1#####2276FungicideAzolePyrazoxyfen71561-11-0NA 189NA 189HerbicidePyrazoleR 23 979 imazalil baseNA 451NA 8092844FungicideAzoleTCMTB21564-17-035603971Microbiocide,MercaptobenzothiazoleFungicideTebuconazole107534-96-3#####3850FungicideAzoleTebufenpyrad119168-77-390102NA 845InsecticidePyrazoleTerrazole2593-15-984701580FungicideAzoleTetraconazole112281-77-3#####NA 979FungicideAzoleThiabendazole148-79-860101587FungicideBenzimidazoleThiabendazole, hypophosphite28558-32-9601021952FungicideBenzimidazolesaltThiophanate23564-06-9#####1684FungicideBenzimidazoleThiophanate-methyl23564-05-8#####1696FungicideBenzimidazoleprecursorTolyl triazole29395-43-1NA 9622950N/AAzoleTriadimefon43121-43-3#####2133FungicideAzoleTriadimenol55219-65-3#####2307Fungicide,AzoleBreakdownproductTriazbutil16227-10-4#####NA 931FungicideAzoleTricyclazole41814-78-2#####5002FungicideAzoleTriflumizole68694-11-1#####2260FungicideAzoleTriflumizole99387-89-0NA 201NA 201FungicideAzoleTriticonazole131983-72-7#####NA 101FungicideAzoleUniconazole83657-22-1#####NA 38Plant GrowthAzoleRegulator2-EEEBC62732-91-6#####1983FungicideBenzimidazoleBenomyl17804-35-2991011552FungicideBenzimidazoleCarbendazim10605-21-7#####2176FungicideBenzimidazoleCarbendazim hydrochloride37574-18-8#####NA 121FungicideBenzimidazoleCarbendazim phosphate52316-55-9991021974FungicideBenzimidazoleChlorflurazole3615-21-2#####NA 139N/ABenzimidazoleCypendazole28559-00-4#####NA 156N/ABenzimidazoleFuberidazole3878-19-1#####NA 150FungicideBenzimidazoleThiabendazole148-79-860101587FungicideBenzimidazoleThiabendazole, hypophosphite28558-32-9601021952FungicideBenzimidazolesaltThiophanate23564-06-9#####1684FungicideBenzimidazoleThiophanate-methyl23564-05-8#####1696FungicideBenzimidazoleprecursor1-(3-51971-67-6#####NA 110N/ACarboxamidechlorophthalimido)cyclohexanecarboxamideCarboxin5234-68-4902011755FungicideCarboxamideCisanilide34484-77-0#####NA 144HerbicideCarboxamideCyclafuramide34849-42-8#####NA 132FungicideCarboxamideFenfuram24691-80-3NA 188NA 187FungicideCarboxamideFurmecyclox (Xyligen B)60568-05-0#####NA 18FungicideCarboxamideMethfuroxam28730-17-8#####NA 949FungicideCarboxamideMetsulfovax21452-18-6NA 189NA 188FungicideCarboxamideNitrofurazone (not subject to59-87-0#####NA 128N/ACarboxamideFIFRA: 8709-e pm 24)Oxycarboxin5259-88-1902021434FungicideCarboxamidep-Benzoquinone61566-21-0#####NA 133N/ACarboxamidesemicarbazoneChlozolinate72391-46-9NA 183NA 182FungicideDicarboximideIprodione36734-19-7#####2081FungicideDicarboximideMyclozolin54864-61-8NA 209NA 208FungicideDicarboximideN-(2-Ethylhexyl)-1-isopropyl-13358-11-7#####NA 121SynergistDicarboximide4-methyl-4-cyclohexene-1,2-dicarboximideN-octyl bicycloheptene113-48-457001396SynergistDicarboximidedicarboximideVinclozolin50471-44-8#####2129FungicideDicarboximideCalcium5895-18-114501NA 139MicrobiocideDithiocarbamateethylenebis(dithiocarbamate)Cufraneb11096-18-7NA 181NA 180FungicideDithiocarbamateDiammonium60731314502NA 140MicrobiocideDithiocarbamateethylenebis(dithiocarbamate)Ferbam14484-64-134801288FungicideDithiocarbamateFerric nitroso dimethyl83542-83-0#####NA 149MicrobiocideDithiocarbamatedithiocarbamateMancopper53988-93-5NA 181NA 180FungicideDithiocarbamateMancozeb223310014504211FungicideDithiocarbamate,Inorganic-ZincManeb12427-38-214505369FungicideDithiocarbamateManeb and nickel sulfate8005-46-7#####NA 158FungicideDithiocarbamate,hexahydrate (014505 + 050505)Inorganic-NickelManganous15339-36-334802NA 304FungicideDithiocarbamatedimethyldithiocarbamateMercuric dimethyl15415-64-234808709MicrobiocideInorganic-Mercury,dithiocarbamateHeavy metal,DithiocarbamateMetam sodium, dihydrate137-42-839003NA 163Fumigant,DithiocarbamateFungicide,Microbiocide,Algaecide,NematicideMetam-sodium6734-80-139003616Fumigant,DithiocarbamateHerbicide,Fungicide,Microbiocide,Algaecide,NematicideMetiram9006-42-214601493FungicideDithiocarbamate,Inorganic-ZincMorpholinomethyl31848-11-0#####NA 158MicrobiocideDithiocarbamatedimethyldithiocarbamateNabam142-59-614503417Fungicide,DithiocarbamateHerbicidePhenylmercuric32407-99-166008NA 555Microbiocide,Organomercury,dimethyldithiocarbamateFungicideDithiocarbamate,Heavy metalPotassium ammonium22221-14-314507NA 141MicrobiocideDithiocarbamateethylenebis(dithiocarbamate)Potassium dimethyl dithiocarbamate128-03-0348031934MicrobiocideDithiocarbamatePotassium N-hydroxymethyl-51026-28-9#####1824N/ADithiocarbamateN-methyldithio carbamatePotassium N-methyldithio137-41-739002970Fumigant,DithiocarbamatecarbamateFungicide,Microbiocide,Algaecide,NematicidePropineb12071-83-9#####NA 155Fungicide,Dithiocarbamate,MicrobiocideInorganic-ZincSodium dimethyl dithio128-04-134804548FungicideDithiocarbamatecarbamateSulfallate95-06-739001115HerbicideDithiocarbamateTert-butyl dimethyl trithio3304-97-0348071383RodentDithiocarbamateperoxycarbamateRepellentTert-NA 1130NA 16691383N/ADithiocarbamatebutyldimethyltrithioperoxycarbamate,other relatedThiram137-26-879801589FungicideDithiocarbamateThiram and NAD and IBA and75497-92-656011NA 463Fungicide,Dithiocarbamate2-methyl-1-Plant Growthnaphthaleneacetamide and 2-Regulatormethyl-1-naphthaleneaceticacidTricopper dichloride7076-63-3#####NA 152MicrobiocideDithiocarbamate,dimethyldithiocarbamateInorganic-CopperZineb12122-67-714506627FungicideDithiocarbamate,Inorganic-ZincZineb-ethylene thiuramNA 1465NA 217NA 216FungicideDithiocarbamate,disulfide adductInorganic-ZincZiram137-30-434805629Fungicide,Dithiocarbamate,Microbiocide,Inorganic-ZincDog and CatRepellentZirm, cyclohexylamine16509-79-8348061328Dog and CatDithiocarbamate,complexRepellent,Inorganic-ZincFungicide2,2′-Dithiobisbenzothiazole120-78-59202NA 109Fungicide,MercaptobenzothiazoleMicrobiocide,Insecticide2-(dithiocyanomethylthio)-NA 1346NA 192NA 191FungicideMercaptobenzothiazolebenzothiazole2-79910-32-0#####NA 925MicrobiocideMercaptobenzothiazole(thiocyanomethylthio)benzothiazolewith 2′-hydroxyethyl-2,3-dibromopropionate2-Mercaptobenzothiazole149-30-451701556Fungicide,MercaptobenzothiazoleMicrobiocide2-Mercaptobenzothiazole, 1-5468-43-951702NA 423Fungicide,Mercaptobenzothiazole(hydroxyethyl)pyridinium saltMicrobiocide2-Mercaptobenzothiazole,53404-53-851708NA 426Fungicide,Mercaptobenzothiazoleferric saltMicrobiocide2-Mercaptobenzothiazole,53404-58-39201NA 108Fungicide,Mercaptobenzothiazolemanganese saltMicrobiocide,Insecticide2-Mercaptobenzothiazole,5902-85-251706NA 424Fungicide,Mercaptobenzothiazolemonoethanolammonium saltMicrobiocide2-Mercaptobenzothiazole,7778-70-351707NA 425Fungicide,Mercaptobenzothiazolepotassium saltMicrobiocide2-Mercaptobenzothiazole,2492-26-4517043064Microbiocide,Mercaptobenzothiazolesodium saltFungicide2-Mercaptobenzothiazole,2492-26-451704613Fungicide,Mercaptobenzothiazolesodium saltMicrobiocide2-Mercaptobenzothiazole, zinc155-04-4517051449Fungicide,Mercaptobenzothiazole,saltMicrobiocideInorganic-Zinc5-Chloro-2-5331-91-9NA 200NA 199N/AMercaptobenzothiazolemercaptobenzothiazole5-Chloro-2-5406-97-3517031238MicrobiocideMercaptobenzothiazolemercaptobenzothiazole, laurylpyridinium salt5-Chloro-2-5406-97-3NA 4211597Microbiocide,Mercaptobenzothiazolemercaptobenzothiazole, laurylFungicidepyridinium salt5-Chloro-2-53404-93-651709NA 427Microbiocide,Mercaptobenzothiazole,mercaptobenzothiazole, zincFungicideInorganic-ZincsaltTCMTB21564-17-035603971Microbiocide,MercaptobenzothiazoleFungicideAncymidol12771-68-5#####1744Plant GrowthPyrimidineRegulatorBupirimate41483-43-6#####2430FungicidePyrimidineCloransulam159518-97-5NA 231NA 231HerbicideTriazolopyrimidineCloransulam-methyl147150-35-4#####NA 112HerbicideTriazolopyrimidineDimethirimol5221-53-4#####NA 128FungicidePyrimidineEthirimol23947-60-6#####NA 129FungicidePyrimidineFenarimol60168-88-9#####1980FungicidePyrimidineFerimzone89269-64-7NA 203NA 202FungicidePyrimidineFlurprimidol56425-91-3#####2320Plant GrowthPyrimidineRegulatorNuarimol63284-71-9#####NA 126FungicidePyrimidinePyrimethanil53112-28-0#####NA 30FungicidePyrimidineAzoxystrobin131860-33-8#####4037FungicideStrobinDimoxystrobin149961-52-4NA 211NA 210FungicideStrobinKresoxim-methyl143390-89-0#####5451FungicideStrobinMetominostrobin133408-50-1NA 211NA 210FungicideStrobinPicoxystrobin117428-22-5NA 211NA 210FungicideStrobinPyraclostrobin175013-18-0NA 211NA 210FungicideStrobinTrifloxystrobin141517-21-7#####5321FungicideStrobinchloroneb2675-77-627301135FungicideSubstituted BenzeneChlorothalonil1897-45-681901677FungicideSubstituted BenzeneDichlobenil1194-65-627401112HerbicideSubstituted benzeneDichloran99-30-93130181FungicideSubstituted BenzenePCNB82-68-856502464Fungicide,Substituted BenzeneNematicide,AlgaecidePCNB, other relatedNA 1100NA 16390464Fungicide,Substituted BenzeneAlgaecide,NematicideCaptafol19044481702NA 787FungicideThiophthalimideCaptafol (cis isomer)2939-80-281701292FungicideThiophthalimideCaptan133-06-281301104FungicideThiophthalimideCaptan, other relatedNA 1074NA 16190104FungicideThiophthalimideFolpet133-07-381601294FungicideThiophthalimideMerpafol cis isomer19044481701NA 163FungicideThiophthalimideBenalaxyl71626-11-4#####NA 102FungicideXylylalanineFuralaxyl57646-30-7NA 188NA 188FungicideXylylalanineL-Metalaxyl69516-34-3#####NA 929FungicideXylylalanineMefenoxam70630-17-0#####4011FungicideXylylalanineMefenoxam, other relatedNA 1152NA 16894011FungicideXylylalanineMetalaxyl57837-19-1#####2132FungicideXylylalanineMetalaxyl-M70630-17-0NA 219NA 218FungicideXylylalanine1-(Alkyl* amino)-3-61791-67-167311NA 586MicrobiocideAlkyl Amino Propaneaminopropane *(47% C12,18% C14, 10% C18, 9% C10,8% C16, 8% C8)1-(Alkyl* amino)-3-61791-63-767301NA 583MicrobiocideAlkyl Amino Propaneaminopropane *(as in fattyacids of coconut oil)1-(Alkyl* amino)-3-68911-78-467306NA 585MicrobiocideAlkyl Amino Propaneaminopropane diacetate*(37% C18′, 29% C16,23% C18, 3% C16′, 3% C14,1.5% C18″, 1% C14′, 1% C12,0.5% C15)1-(Alkyl* amino)-3-NA 119167313NA 167MicrobiocideAlkyl Amino Propaneaminopropane diacetate *(as infatty acids of coconut oil)1-(Alkyl* amino)-3-NA 119267319NA 167Microbiocide,Alkyl Amino Propaneaminopropane monoacetateAlgaecide*(47% C12, 18% C14, 10% C18,9% C10, 8% C16, 8% C8)1-(Alkyl* amino)-3-NA 119367304NA 167MicrobiocideAlkyl Amino Propaneaminopropane propionate-copper acetate complex1-(alkyl-amino)-3-NA 1494NA 221NA 221MicrobiocideAlkyl Amino Propaneaminopropane hydrochloride1-(alkylamino)-3-68155-37-3673101830MicrobiocideAlkyl Amino Propaneaminopropane1-(alkylamino)-3-NA 1495NA 221NA 221MicrobiocideAlkyl Amino Propanecarboxymethylaminopropane1-Alkyl (C6 to C18) amino-3-NA 994NA 7212365MicrobiocideAlkyl Amino Propaneaminopropane acetate1-alkyl (C6-C18) amino-3-61791-64-8673021954MicrobiocideAlkyl Amino Propaneaminopropane diacetate1-alkylamino-2-aminopropane61791-64-8673021335MicrobiocideAlkyl Amino Propanemonoacetate, alkyl derivedfrom coconut oil fatty acids1-Alkylamino-3-aminopropane68155-43-1673091972Microbiocide,Alkyl Amino Propanehydroxyacetate, alkyl derivedSoap/Surfactantfrom coconut oil fatty acidsAlkyl (53% C12, 19% C14,61791-58-0673051780MicrobiocideAlkyl Amino Propane8.5% C16, 7% C8, 6.5% C10,6% C18)-1,3-propane diamineAlkyl-1,3-propylene diamine61790-63-7NA 5581380Microbiocide,Alkyl Amino Propaneacetate, alkyl derived fromSoap/Surfactantcoconut oil fatty acidsAlkyl-1,3-propylene diamine68155-42-0#####1841Microbiocide,Alkyl Amino Propaneadipate, alkyl derived fromSoap/Surfactantcoconut oil fatty acidsAlkyl-1,3-propylene diamine,NA 287NA 5591379Microbiocide,Alkyl Amino Propanealkyl derived from coconut oilSoap/Surfactantfatty acidsN-(2-cyanoethyl)-N-alkyl (C6-C18)-NA 187673211957AdjuvantAlkyl Amino Propane1,3-diamino propaneN-Alkyl-1,3-propylene diamine68188-29-4673071735Microbiocide,Alkyl Amino Propanemonobenzoate, alkyl derivedSoap/Surfactantfrom coconut oil fatty acidsTall oil fatty acid soap of N-61790-55-4NA 9243463Microbiocide,Alkyl Amino Propanealkyl (C16-C18) propylInsecticidediamine2,2′-Methylenebis(4,6-1940-43-855004NA 455MicrobiocideChlorinated Phenoldichlorophenol)2,2′-Thiobis(4,6-97-18-764201NA 539N/AChlorinated Phenoldichlorophenol)2,2,2-Trichloro-N-3583-63-9#####NA 151N/AChlorinated Phenol(pentachlorophenyl)acetimidoylchloride2,2-methylene bis(4,6-68957-70-0550061843MicrobiocideChlorinated Phenoldichlorophenol), sodium salt2,3,4,6-tetrachlorophenol,53535-27-6630071725WoodChlorinated phenolpotassium saltPreservative,Fungicide2,4,5-trichlorophenol95-95-4642101382Microbiocide,Chlorinated phenolAlgaecide2,4,5-Trichlorophenol salt of53404-83-464211NA 542N/AChlorinated Phenol2,6-bis((dimethylamino)methyl)cyclohexanone2,4,5-trichlorophenol,35471-43-3642041050MicrobiocideChlorinated phenolpotassium salt2,4,5-trichlorophenol,NA 1128NA 16691050MicrobiocideChlorinated phenolpotassium salt, other related2,4,5-trichlorophenol, sodium136-32-3642171656MicrobiocideChlorinated phenolsalt2,4,5-Trichlorophenol, sodium3784-03-064220NA 545Microbiocide,Chlorinated PhenolsaltAlgaecide2,4,6-trichlorophenol88-06-264212640MicrobiocideChlorinated phenol2,4-dichlorophenol120-83-2NA 1052499N/AChlorinated phenol2-(trichlorophenoxy)ethyl69633-04-1#####NA 152HerbicideChlorinated Phenolhydrogen sulfate2-chloro-4-phenylphenol92-04-662206846MicrobiocideChlorinated Phenol2-chloro-4-phenylphenol,18128-16-0622071061MicrobiocideChlorinated Phenolpotassium salt2-chloro-4-phenylphenol,31366-97-9622151632MicrobiocideChlorinated Phenolsodium salt2-Chlorophenol95-57-862204NA 504MicrobiocideChlorinated Phenol3-chloro-2-biphenylol, sodium10605-11-562213NA 505MicrobiocideChlorinated Phenolsalt4 & 6-chloro-2-phenylphenolNA 964NA 4191566MicrobiocideChlorinated Phenol4 & 6-chloro-2-phenylphenol,NA 965NA 4201604MicrobiocideChlorinated Phenolpotassium salts, mixed4 & 6-chloro-2-phenylphenol,NA 963NA 4131594MicrobiocideChlorinated Phenolsodium salts, mixed4 & 6-chloro-2-phenylphenol,NA 1132NA 16691566MicrobiocideChlorinated phenolother related4 or 6-chloro-2-phenylphenol53537-62-562216NA 507MicrobiocideChlorinated Phenol4 or 6-chloro-2-phenylphenol,53537-63-662214NA 506MicrobiocideChlorinated Phenoldiethanolamine salt4,6-dichloro-2-phenylphenol5335-24-0642161062MicrobiocideChlorinated phenol4,6-dichloro-2-phenylphenol,53404-30-1642151059MicrobiocideChlorinated phenolpotassium salt4-chloro-2-cyclopentyl phenol,35471-38-6642141237Microbiocide,Chlorinated phenolpotassium saltFungicide4-chloro-2-cyclopentylphenol13347-42-764202836Microbiocide,Chlorinated phenolFungicide4-chloro-2-phenylphenol607-12-562208945MicrobiocideChlorinated Phenol4-chloro-2-phenylphenol,53404-21-062209947MicrobiocideChlorinated Phenolpotassium salt4-chloro-2-phenylphenol,10605-10-462212946MicrobiocideChlorinated Phenolsodium salt4-chloro-cyclopentylphenol,53404-20-9642181395Microbiocide,Chlorinated phenolsodium saltFungicide6-chloro-2-phenylphenol85-97-262210948MicrobiocideChlorinated Phenol6-chloro-2-phenylphenol,18128-17-162211950MicrobiocideChlorinated Phenolpotassium salt6-chloro-2-phenylphenol,63992-41-6NA 414949N/AChlorinated phenolsodium salt6-chlorothymol89-68-980403NA 775N/AChlorinated Phenol6-tert-Butyl-4-chloro-m-cresol30894-16-7#####NA 127MicrobiocideChlorinated PhenolChlorbisan4418-66-064208127MicrobiocideChlorinated PhenolChloroxylenol88-04-086801925MicrobiocideChlorinated phenolCopper pentachlorophenate15773-35-063011NA 512WoodChlorinated Phenol,Preservative,Inorganic-CopperMicrobiocide,Algaecide,FungicideDehydroabietylamine35109-57-04202NA 72WoodChlorinated PhenolpentachlorophenatePreservative,Microbiocide,Algaecide,FungicideDichlorophene97-23-455001206Herbicide,Chlorinated PhenolFungicide,MicrobiocideDisodium 2,2′-3247-34-544903NA 380N/AChlorinated Phenolmethylenebis(3,4,6-trichlorophenate)Ethylmercury22232-28-641504NA 359MicrobiocideOrganomercury,pentachlorophenateChlorinated Phenol,Heavy metalFenticlor97-24-564209NA 541MicrobiocideChlorinated PhenolHexachlorophene70-30-444901322Microbiocide,Chlorinated PhenolFungicideHexachlorophene, sodium salt5736-15-244902413MicrobiocideChlorinated PhenolOrtho-benzyl-para-120-32-162201522Microbiocide,Chlorinated phenolchlorophenolFungicideOrtho-benzyl-para-35471-49-962202936MicrobiocideChlorinated phenolchlorophenol, potassium saltOrtho-benzyl-para-3184-65-462203937Microbiocide,Chlorinated phenolchlorophenol, sodium saltFungicidePara-chloro-meta-cresol59-50-7642061813Microbiocide,Chlorinated PhenolFungicidepara-Chloro-ortho-cresol1570-64-562190NA 503N/AChlorinated PhenolPara-chlorophenol106-48-9NA 1241572N/AChlorinated phenolPCP87-86-563001465WoodChlorinated PhenolPreservative,Microbiocide,Algaecide,Fungicide,Molluscicide,HerbicidePCP, other relatedNA 1101NA 16390465WoodChlorinated PhenolPreservative,Microbiocide,Algaecide,Fungicide,MolluscicidePCP, potassium salt7978-73-6630021049WoodChlorinated PhenolPreservative,Microbiocide,Algaecide,Fungicide,MolluscicidePCP, sodium salt131-52-263003540WoodChlorinated PhenolPreservative,Microbiocide,Algaecide,Fungicide,MolluscicidePCP, sodium salt, other relatedNA 1110NA 16490540WoodChlorinated PhenolPreservative,Microbiocide,Algaecide,Fungicide,MolluscicidePentachlorophenol, zinc salt2917-32-063008NA 510WoodChlorinated Phenol,Preservative,Inorganic-ZincMicrobiocide,Algaecide,FungicidePentachlorophenyl laurate3772-94-963010NA 511WoodChlorinated PhenolPreservative,Microbiocide,Algaecide,FungicidePotassium 2,2′-67923-62-044904NA 381MicrobiocideChlorinated Phenolmethylenebis(3,4,6-trichlorophenate)Potassium 2,4,6-2591-21-164219NA 544MicrobiocideChlorinated PhenoltrichlorophenatePotassium ortho-cyclopentyl-35471-38-6642141542Microbiocide,Chlorinated phenolpara-chlorophenateFungicideSodium 2,2′-methylenebis(4-10254-48-555005NA 456Insecticide,Chlorinated Phenolchlorophenate)Fungicide,MicrobiocideSodium chlorophenates35535-81-062205773N/AChlorinated PhenolSodium dichlorophenateNA 1399NA 197NA 196Fungicide,Chlorinated PhenolMicrobiocideSodium p-chloro-m-cresolate15733-22-964205NA 540MicrobiocideChlorinated PhenolTetrachlorophenol25167-83-363004777WoodChlorinated phenolPreservative,FungicideTetrachlorophenol, alkylamineNA 1007NA 9381401WoodChlorinated phenolsaltPreservative,FungicideTetrachlorophenol, coconutNA 1008NA 9391455WoodChlorinated phenolamine saltPreservative,FungicideTetrachlorophenol, otherNA 1118NA 16590777WoodChlorinated phenolrelatedPreservative,FungicideTetrachlorophenol, potassium53535-27-6630071753WoodChlorinated phenolsaltPreservative,FungicideTetrachlorophenol, sodium salt25567-55-963005776WoodChlorinated phenolPreservative,FungicideTetrachlorophenol, sodium salt,NA 1117NA 16590776WoodChlorinated phenolother relatedPreservative,FungicideTetrachlorophenols, alkyl*137543-70-563006NA 509WoodChlorinated Phenolamine salt *(as in fatty acids ofPreservative,coconut oil)FungicideTrichlorophenol95-95-4642101189Microbiocide,Chlorinated phenolAlgaecideTrichlorophenol, sodium salt136-32-364217960Microbiocide,Chlorinated phenolAlgaecideTrichlorophenol, sodium salt,NA 1127NA 16690960MicrobiocideChlorinated phenolother relatedTriclosan3380-34-5549011371MicrobiocideChlorinated PhenolVancide 30-R6385-58-664203612MicrobiocideChlorinated PhenolZinc 2,4,5-trichlorophenate136-24-364221NA 546N/AChlorinated Phenol,Inorganic-ZincZinc trichlorophenate30143-22-764213NA 543MicrobiocideChlorinated Phenol,Inorganic-Zinc1,3-bis (dihydroxymethyl)-5,5-6440-58-0#####2298Fungicide,HydantoindimethylhydantoinHerbicide,Microbiocide1,3-dibromo-5,5-77-48-563174036Microbiocide,HydantoindimethylhydantoinFungicide,Herbicide1,3-dichloro-5,5-118-52-52850137Microbiocide,HydantoindimethylhydantoinFungicide,Herbicide1,3-Dichloro-5-ethyl-5-89415-87-2#####2264Microbiocide,HydantoinmethylhydantoinFungicide,Herbicide1-bromo-3-chloro-5,5-dimethyl16079-88-263152080Microbiocide,HydantoinhydantoinFungicide,Herbicide1-Hydroxymethyl-5,5-dimethyl116-25-6#####2306Fungicide,HydantoinhydantoinHerbicide,Microbiocide3-Bromo-1-chloro-5,5-126-06-76322NA 92Microbiocide,HydantoindimethylhydantoinFungicide,Herbicide3-Hydroxymethyl-5,5-dimethylNA 1478NA 220NA 219FungicideHydantoinhydantoinDimethylol dimethyl hydantoin6440-58-0#####2524Fungicide,HydantoinHerbicide,MicrobiocideAcetalized polyvinyl alcoholNA 118546926NA 166MicrobiocideIodine Compoundcomplexed with iodineAlkyl (29% C14, 29% C13,NA 973NA 5572063MicrobiocideIodine Compound21% C12, 21% C15)poly(oxypropylene) poly(oxyethylene)-iodine complexAlkyl (C12-C15)-NA 972NA 5561734MicrobiocideIodine Compoundpoly(oxypropylene)poly(oxyethylene)-iodinecomplexAlkyl(C12-C15)NA 119546918NA 168MicrobiocideIodine Compoundpoly(oxypropylene)poly(oxyethylene)-iodine complexAlkyl* (ethyl cycloimidinium)NA 121146906NA 169MicrobiocideIodine Compound3-hydroxy-3-ethyl sodiumalcoholate, 2-methyl sodiumcarboxylate-tridecylpolyoxyethylene ethanolAlkyl* dimethyl 3,4-NA 119846907NA 168Microbiocide,Iodine Compound,dichlorobenzyl ammoniumMicrobiocideQuaternarychlorideAmmoniumpolyethoxypolypropoxypolyethoxyethanol-Compoundiodine complex*(50% C12, 30% C14, 1Alkyl*NA 121446925NA 170MicrobiocideIodine Compoundpoly(oxypropylene)poly(oxyethylene)-iodine complex*(43% C10, 30% C14, 12% C12,10% C16, 5% C18)Butoxy polypropoxy68610-00-4469011633MicrobiocideIodine Compoundpolyethoxy ethanol-iodinecomplexDiethanolamine myristate-53404-40-346910NA 406MicrobiocideIodine Compoundiodine complexIodophors39392-86-4NA 213NA 212MicrobiocideIodine CompoundNonyl phenoxy polyNA 927NA 391610MicrobiocideIodine Compound(oxyethylene) amine sulfonateethanol-iodineNonyl phenoxy35860-86-746903870MicrobiocideIodine Compound,polyoxyethylene ethanol-iodinePolyalkyloxycomplexCompoundOctylphenoxy polyethoxy53404-04-9469152172Microbiocide,Iodine Compoundethanol-iodine complexFungicide,HerbicidePoly oxyethylene ethanol82010-75-1469242261MicrobiocideIodine Compoundmonoesters of 5- (and 6-)carboxy-4-hexyl-2-cyclohexene-1-octanoic acid,complex with iodinePoly propoxy poly ethoxyNA 232NA 4531828MicrobiocideIodine Compoundethanol, I2 complexPolyethoxy polypropoxy26617-87-8469041585MicrobiocideIodine Compoundpolyethoxy ethanol-iodinecomplexPolyethoxy polypropoxyNA 128646909NA 174MicrobiocideIodine Compoundpolyethoxy ethanol-iodinecomplexPolyethoxypolypropoxypolyethoxyethanol-NA 128746913NA 175MicrobiocideIodine Compound,n-alkyl (54% C12,Quaternary18% C14, 9% C16, 9% C18,Ammonium5% C10, 5% C8) di(beta-Compoundhydroxyethyl) benzyl amPolyethylene glycol ether of68439-47-4469212121MicrobiocideIodine Compoundlinear secondary alcohol-iodine complexPolyvinyl pyrrolidone-iodine25655-41-8469141611MicrobiocideIodine CompoundcomplexSodium dodecylbenzene53467-01-9469201569MicrobiocideIodine Compoundsulfonate-iodine complexSodium N-alkyl-N-palmitoylNA 290NA 5621568MicrobiocideIodine Compoundtaurate-iodine complexSodium N-cyclohexyl-N-53404-81-2469192089MicrobiocideIodine Compoundpalmitoyl taurate-iodinecomplexTetraglycine hydroperiodide7097-60-1469231923MicrobiocideIodine CompoundTridecylpoly(ethyleneoxy)ethanol-53404-05-046911NA 407MicrobiocideIodine Compoundiodine complexTriethanolamine octylsulfate-82010-77-346922NA 409MicrobiocideIodine Compoundiodine complex2-(4-chlorophenylmethyl)-26530-09-6#####NA 125MicrobiocideIsothiazolone3(2H)-isothiazolone2-cyclohexyl-4,5-dichloro-4-57063-29-3#####NA 166InsecticideIsothiazoloneisothiazolin-3-one2-cyclohexyl-4,5-dichloro-4-57063-29-3#####NA 938InsecticideIsothiazoloneisothioazolin-3-one2-Methyl-3(2H)-isothiazolone,57373-20-3#####NA 895MicrobiocideIsothiazolonecalcium chloride complex2-methyl-4,5-trimethylene-4-82633-79-2#####5013MicrobiocideIsothiazoloneisothiazolin-3-one2-methyl-4-isothiazolin-3-one2682-20-4#####2039MicrobiocideIsothiazolone3(2H)-chloro-2-methyl-3(2H)-57373-19-0#####NA 894MicrobiocideIsothiazoloneisothiazolone, calcium chloridecomplex4,5-dichloro-2-n-octyl-3(2H)-64359-81-5#####3982Microbiocide,IsothiazoloneisothiazoloneAntifoulant4-chloro-2-n-octyl-3(2H)-64359-80-4#####NA 102MicrobiocideIsothiazoloneisothiazolone5-chloro-2-((4-83542-80-7#####NA 125MicrobiocideIsothiazolonechlorophenyl)methyl)-3(2H)-isothiazolone, compd. With 2-((4-chlorophenyl)methyl)-3(2h)-isothiazolone (1:1)5-chloro-2-(4-66159-95-3#####NA 125MicrobiocideIsothiazolonechlorophenylmethyl)-3(2H)-isothiazolone5-chloro-2-methyl-4-26172-55-4#####2038MicrobiocideIsothiazoloneisothiazolin-3-one5-chloro-2-methyl-4-55965-87-2#####NA 896MicrobiocideIsothiazoloneisothiazolin-3-one calciumchloride with 2-methyl-4-isothazolin-3-one calciumchlorideKathon 886 (kathon biocide)55965-84-9#####NA 24MicrobiocideIsothiazoloneOcthilinone26530-20-1999011881Microbiocide,IsothiazoloneFungicide2,4,6-triisopropyl phenol376389NA 1163492N/APhenols2,4-xylenol105-67-986804638Solvent,PhenolsFungicide,Microbiocide2,6-bis (1-methyl heptadecyl)-5012-62-4NA 1063069MicrobiocidePhenolsp-cresol2-tert-Amylphenol87-26-364119NA 538MicrobiocidePhenols4-Hexylresorcinol136-77-671403NA 671N/APhenols4-Octylresorcinol6565-70-471402NA 670N/APhenols5-isopropyl-o-cresol499-75-2221041877MicrobiocidePhenolsButylated hydroxy toluene128-37-0221051309PreservativePhenolsCarbolic acid108-95-264001107Microbiocide,PhenolsNematicideCoal tar phenols1319-77-3221011720N/APetroleum derivative,PhenolsCresol1319-77-3NA 219NA 218InsectPhenolsRepellent,MicrobiocideDiisobutyl cresoxy ethoxy53466-87-8691551643MicrobiocidePhenolsethyl dimethyl benzylammonium chloride-ortho-phenylphenol ethoxy nonylphenol complexDiisopropyl cresol31291-59-522107NA 176MicrobiocidePhenolsDiisopropyl phenolsNA 170NA 3293638N/APhenolsHydroxymercury cresol12379-66-746001NA 390MicrobiocideInorganic-Mercury,Heavy metal, PhenolsIsopropyl cresol499-75-2221041161MicrobiocidePhenolsIsopropyl phenol25168-06-3NA 1553256MicrobiocidePhenolsMeta-cresol108-39-422102378MicrobiocidePhenolsNonyl phenol25154-52-3NA 443304AdjuvantPhenolso-cresol95-48-7NA 3743113MicrobiocidePhenolso-Phenylphenol, alkyl* amine-82010-74-064107NA 533MicrobiocidePhenols, Inorganic-zinc salt of *(100% C18)Zinco-Phenylphenol,53404-71-064109NA 534MicrobiocidePhenolstetradecylamine saltOctylphenol27193-28-864118NA 537N/APhenolsOrtho-phenylphenol90-43-764103448MicrobiocidePhenolsOrtho-phenylphenol,52704-98-064116890MicrobiocidePhenolsammonium saltOrtho-phenylphenol, potassium13707-65-864108935MicrobiocidePhenolssaltOrtho-phenylphenol, sodium132-27-464104248MicrobiocidePhenolssaltp-cresol106-44-5NA 3753114MicrobiocidePhenolsp-Cresyl acetate140-39-6NA 186NA 186MicrobiocidePhenolsPara-tert-amylphenol80-46-664101900MicrobiocidePhenolsPara-tert-amylphenol,53404-18-5641111056MicrobiocidePhenolspotassium saltPara-tert-butylphenol98-54-4641131000MicrobiocidePhenolsPhenol, dodecyl-, mixed27193-86-8NA 6563323N/APhenolsisomersPhenol, ferrous saltNA 686NA 1261862N/APhenolsPhenols64743-03-9NA 189NA 189Microbiocide,PhenolsHerbicidePolyvinylpyrrolidone-53403-98-864110NA 535MicrobiocidePhenolsorthophenylphenol complexPropoxur phenol4812-20-8#####NA 118BreakdownPhenolsproductResorcinol108-46-3714013375N/APhenolsSodium cresolate34689-46-8#####NA 142MicrobiocidePhenolsSodium para-tert-amylphenate31366-95-7641121541Microbiocide,PhenolsFungicideSodium para-tert-butylphenate5787-50-8641151540MicrobiocidePhenolsSodium phenate139-02-6640022164MicrobiocidePhenolsThymol89-83-880402991DyePhenolsXylenol (unspec. Or mixed1300-71-686805NA 837N/APhenolsfrom 086804)2-(2-(p-(diisobutyl) phenoxy)121-54-06912266MicrobiocideQuaternaryethoxy) ethyl dimethylAmmoniumammonium chlorideCompound2-(2-(p-(diisobutyl) phenoxy)121-54-069164NA 166MicrobiocideQuaternaryethoxy) ethyl dimethylAmmoniumammonium chlorideCompound3-(trimethoxysilyl) propyl27668-52-6#####2127MicrobiocideQuaternarydimethyl octadecyl ammoniumAmmoniumchlorideCompound3-alkoxy (C12-C15)-2-68187-63-3#####2020N/AQuaternaryhydroxypropyl trimethylAmmoniumammonium chlorideCompoundAcylamido alkylbenzylNA 993NA 7051442Algaecide,Quaternarydimethyl ammonium chlorideMicrobiocideAmmoniumCompoundAlkenyl (90% C18, 10% C16)NA 1313NA 1231243Microbiocide,Quaternarydimethyl ethyl ammoniumAdjuvantAmmoniumbromideCompoundAlkenyl* dimethyl ethyl6458-13-569102NA 620Algaecide,Quaternaryammonium bromideMicrobiocideAmmonium*(90% C18′, 10% C16′)CompoundAlkenyl* dimethyl ethylNA 118769198NA 167MicrobiocideQuaternaryammonium bromideAmmonium*(90% C18′, 10% C16′)CompoundAlkyl (100% C14) dimethyl139-08-2691072373Algaecide,Quaternarybenzyl ammonium chlorideMicrobiocideAmmoniumCompoundAlkyl (47% C12, 18% C14,NA 986691431970Algaecide,Quaternary10% C18, 10% C16, 15% C8-C10)MicrobiocideAmmoniumdimethylbenzylCompoundammonium chlorideAlkyl (50% C12, 30% C14,8023-53-8691102027Algaecide,Quaternary17% C16, 3% C18) dimethylMicrobiocideAmmoniumdichlorobenzyl ammoniumCompoundchlorideAlkyl (50% C12, 30% C14,NA 987691431850Algaecide,Quaternary17% C16, 3% C18)MicrobiocideAmmoniumdimethylbenzyl ammoniumCompoundchlorideAlkyl (50% C12, 30% C14,8045-21-4691111849Algaecide,Quaternary17% C16, 3% C18)MicrobiocideAmmoniumdimethylethylbenzylCompoundammonium chlorideAlkyl (50% C14, 40% C12,NA 988691431846Algaecide,Quaternary10% C16) dimethylbenzylMicrobiocideAmmoniumammonium chlorideCompoundAlkyl (50% C14, 40% C12,68989-01-569171324Algaecide,Quaternary10% C16) dimethylbenzylMicrobiocideAmmoniumammonium saccharinateCompoundAlkyl (53% C12, 19% C14,61789-71-7691403535Algaecide,Quaternary8.5% C16, 7% C8, 6.5% C10,MicrobiocideAmmonium6% C18) dimethylCompoundbenzylammonium chlorideAlkyl (58% C14, 28% C16,NA 989691431912Algaecide,Quaternary14% C12) dimethylbenzylMicrobiocideAmmoniumammonium chlorideCompoundAlkyl (58% C18, 40% C16,68391-03-7691632228MicrobiocideQuaternary1% C14, 1% C12) trimethylAmmoniumammonium chlorideCompoundAlkyl (60% C14, 25% C12,68424-85-1691051956Algaecide,Quaternary15% C16) dimethylbenzylMicrobiocideAmmoniumammonium chlorideCompoundAlkyl (60% C14, 30% C16,NA 976691431847Algaecide,Quaternary5% C12, 5% C18)MicrobiocideAmmoniumdimethylbenzyl ammoniumCompoundchlorideAlkyl (61% C12, 23% C14,68989-00-4#####1960Algaecide,Quaternary11% C16, 3% C10, 2% C8)MicrobiocideAmmoniumdimethylbenzyl ammoniumCompoundchlorideAlkyl (61% C12, 23% C14,NA 977691431975Algaecide,Quaternary11% C16, 5% C18) dimethylMicrobiocideAmmoniumbenzyl ammonium chlorideCompoundAlkyl (61% C12, 23% C14,NA 978691432060Algaecide,Quaternary11% C16, 5% C8, C10, C18)MicrobiocideAmmoniumdimethylbenzyl ammoniumCompoundchlorideAlkyl61789-71-7691402375Algaecide,Quaternary(61% C12, 23% C14, 11% C16, 2.5%MicrobiocideAmmoniumC8 & C10, 2.5% C18)Compounddimethyl benzyl ammoniumchlorideAlkyl (65% C12, 25% C14,NA 979691431971Algaecide,Quaternary10% C16) dimethylbenzylMicrobiocideAmmoniumammonium chlorideCompoundAlkyl (67% C12, 25% C14,NA 980691431853Algaecide,Quaternary7% C16, 1% C8, C10, C18)MicrobiocideAmmoniumdimethylbenzyl ammoniumCompoundchlorideAlkyl (68% C12, 32% C14)NA 1190#####NA 167Algaecide,Quaternarydimethyl dimethylbenzylMicrobiocideAmmoniumammonium chlorideCompoundAlkyl (68% C12, 32% C14)85409-23-0691541854Algaecide,QuaternarydimethylethylbenzylFungicide,Ammoniumammonium chlorideMicrobiocideCompoundAlkyl (70% C18, 27% C16,68391-03-76916310MicrobiocideQuaternary3% C14) trimethyl ammoniumAmmoniumchlorideCompoundAlkyl (90% C14, 5% C12,8023-53-8691101909Algaecide,Quaternary5% C16) dimethylMicrobiocideAmmoniumdichlorobenzyl ammoniumCompoundchlorideAlkyl (90% C14, 5% C12,68527-84-4691462057Algaecide,Quaternary5% C16) dimethyl ethylMicrobiocideAmmoniumammonium bromideCompoundAlkyl (90% C14, 5% C12,NA 981691431977Algaecide,Quaternary5% C16) dimethylbenzylMicrobiocideAmmoniumammonium chlorideCompoundAlkyl (93% C14, 4% C12,NA 1031691431991Algaecide,Quaternary3% C16) dimethylbenzylMicrobiocideAmmoniumammonium chlorideCompoundAlkyl (95% C14, 3% C12,68424-85-1691053855Algaecide,Quaternary2% C16) dimethyl benzylMicrobiocideAmmoniumammonium chlorideCompoundAlkyl (95% C14, 3% C12,NA 982691842152Algaecide,Quaternary2% C16) dimethyl benzylMicrobiocideAmmoniumammonium chloride dihydrateCompoundAlkyl (95% C14, 3% C12,NA 1322NA 5833897Algaecide,Quaternary2% C16) dimethyl benzylMicrobiocideAmmoniumammonium chlorideCompoundmonohydrateAlkyl (98% C12, 2% C14)53516-75-9691121839Algaecide,Quaternarydimethyl 1-naphthylmethylMicrobiocideAmmoniumammonium chlorideCompoundAlkyl (C10-16) dimethyl amine61788-90-7NA 4013896Algaecide,QuaternaryoxideMicrobiocideAmmoniumCompoundAlkyl (C14, C12, C16)NA 985NA 5872374Algaecide,Quaternarydimethyl benzyl ammoniumMicrobiocideAmmoniumchlorideCompoundAlkyl (C8-C18) bis (2-61789-68-2#####2031MicrobiocideQuaternaryhydroxyethyl) benzylAmmoniumammonium chlorideCompoundAlkyl (C8-C18) bis (2-NA 119669148NA 168Algaecide,Quaternaryhydroxyethyl) benzylMicrobiocideAmmoniumammonium chlorideCompoundAlkyl dimethyl cumenylNA 983NA 5841919Algaecide,Quaternaryammonium chlorideMicrobiocideAmmoniumCompoundAlkyl dimethyl ethyl benzylNA 974NA 5801002MicrobiocideQuaternaryammonium cyclohexylAmmoniumsulfonateCompoundAlkyl dimethyl ethylbenzyl71808-54-3691351722Algaecide,Quaternaryammonium cyclohexylMicrobiocideAmmoniumsulfamateCompoundAlkyl dimethyl isopropylNA 97569188884MicrobiocideQuaternarybenzyl ammonium chlorideAmmoniumCompoundAlkyl monoethyoxyethanol,NA 305NA 5771045MicrobiocideQuaternarydiethoxyethyl benzylAmmoniumammonium chlorideCompoundAlkyl morpholiniumNA 1523NA 223NA 223FungicideQuaternaryethosulphate (1% C14, 22%AmmoniumC16, 77% C18)CompoundAlkyl trimethyl ammonium68424-92-0#####1827MicrobiocideQuaternarybromidesAmmoniumCompoundAlkyl(68% C12,NA 1068NA 1595126AlgaecideQuaternary32% C14)dimethylAmmoniumdimethylbenzyl ammoniumCompoundchlorideAlkyl* bis(2-91721-81-2#####NA 113N/AQuaternaryhydroxyethyl)benzylAmmoniumammonium chlorideCompound*(57% C10, 20% C12, 11% C14,9% C18, 2% C16, 1% C8)Alkyl* dimethyl 3,4-NA 1197#####NA 168Algaecide,Quaternarydichlorobenzyl ammoniumMicrobiocideAmmoniumchloride *(42% C12, 27% C14,Compound13% C16, 18% C8-C18)Alkyl* dimethyl 3,4-68989-02-6#####NA 112Algaecide,Quaternarydichlorobenzyl ammoniumMicrobiocideAmmoniumchloride *(50% C14, 40% C12,Compound10% C16)Alkyl* dimethyl 3,4-92129-28-769182NA 648Algaecide,Quaternarydichlorobenzyl ammoniumMicrobiocideAmmoniumchloride *(55% C14, 23% C12,Compound20% C16, 2% C18)Alkyl* dimethyl 3,4-68989-02-6#####NA 124Algaecide,Quaternarydichlorobenzyl ammoniumMicrobiocideAmmoniumchloride *(60% C14, 30% C16,Compound10% C12)Alkyl* dimethyl 3,4-68989-02-669180NA 646Algaecide,Quaternarydichlorobenzyl ammoniumMicrobiocideAmmoniumchloride *(60% C12, 25% C14,Compound15% C16)Alkyl* dimethyl 3,4-68989-02-6#####NA 113Algaecide,Quaternarydichlorobenzyl ammoniumMicrobiocideAmmoniumchloride *(63% C12, 23% C14,Compound14% C16)Alkyl* dimethyl 3,4-92129-28-769196NA 653Algaecide,Quaternarydichlorobenzyl ammoniumMicrobiocideAmmoniumchloride *(65% C12, 22% C14,Compound10% C16, 3% C18)Alkyl* dimethyl 3,4-68989-02-6#####NA 114Algaecide,Quaternarydichlorobenzyl ammoniumMicrobiocideAmmoniumchloride *(68% C12, 27% C14,Compound5% C16)Alkyl* dimethyl 3,4-68568-47-8#####NA 124Algaecide,Quaternarydichlorobenzyl ammoniumMicrobiocideAmmoniumchloride *(75% C12, 25% C14)CompoundAlkyl* dimethyl 3,4-68989-02-6#####NA 124Algaecide,Quaternarydichlorobenzyl ammoniumMicrobiocideAmmoniumchloride *(75% C12, 25% C14)CompoundAlkyl* dimethyl 3,4-68989-02-669145NA 635Algaecide,Quaternarydichlorobenzyl ammoniumMicrobiocideAmmoniumchloride *(90% C14, 5% C16,Compound5% C12)Alkyl* dimethyl 3,4-68989-02-6#####NA 115Algaecide,Quaternarydichlorobenzyl ammoniumMicrobiocideAmmoniumchloride *(C12 65%, C14 25%,CompoundC16 10%)Alkyl* dimethyl 3,4-NA 119846907NA 168Microbiocide,Iodine Compound,dichlorobenzyl ammoniumMicrobiocideQuaternarychlorideAmmoniumpolyethoxypolypropoxypolyethoxyethanol-Compoundiodine complex*(50% C12, 30% C14, 1Alkyl* dimethyl benzyl71011-24-0#####NA 113Algaecide,Quaternaryammonium bentonite *(as inMicrobiocideAmmoniumfatty acids of tallow)CompoundAlkyl* dimethyl benzyl122-18-969108NA 623Algaecide,Quaternaryammonium chloride *(100%MicrobiocideAmmoniumC16)CompoundAlkyl* dimethyl benzyl122-19-0#####NA 114Algaecide,Quaternaryammonium chloride *(100%MicrobiocideAmmoniumC18)CompoundAlkyl* dimethyl benzyl68391-01-569195NA 652Algaecide,Quaternaryammonium chlorideMicrobiocideAmmonium*(41% C14, 28% C12, 19% C18,Compound12% C16)Alkyl* dimethyl benzylNA 119969168NA 168Algaecide,Quaternaryammonium chlorideMicrobiocideAmmonium*(47% C12, 18% C14, 15%(C5-C15),Compound10% C18, 10% C16)Alkyl* dimethyl benzyl8001-54-569106NA 622Microbiocide,Quaternaryammonium chlorideAlgaecide,Ammonium*(50% C12, 30% C14, 17% C16,HerbicideCompound3% C18)Alkyl* dimethyl benzyl68391-01-5#####NA 113Algaecide,Quaternaryammonium chloride *(55%MicrobiocideAmmoniumC16, 27% C12, 16% C14, 2%CompoundC18)Alkyl* dimethyl benzyl68391-01-569169NA 641Algaecide,Quaternaryammonium chlorideMicrobiocideAmmonium*(55% C16, 20% C14, 20% C12,Compound5% C18)Alkyl* dimethyl benzylNA 120069141NA 168Algaecide,Quaternaryammonium chlorideMicrobiocideAmmonium*(58% C14, 28% C16, 14% C12)CompoundAlkyl* dimethyl benzyl68424-85-169161NA 168Algaecide,Quaternaryammonium chloride *(60%MicrobiocideAmmoniumC14, 30% C16, 10% C12)CompoundAlkyl* dimethyl benzylNA 120169137NA 168Algaecide,Quaternaryammonium chlorideMicrobiocideAmmonium*(60% C14, 25% C12, 15% C16)CompoundAlkyl* dimethyl benzyl53516-76-069104NA 621Algaecide,Quaternaryammonium chlorideMicrobiocideAmmonium*(60% C14, 30% C16, 5% C18,Compound5% C12)Alkyl* dimethyl benzyl68391-01-569189NA 650Algaecide,Quaternaryammonium chloride *(61%MicrobiocideAmmoniumC12, 23% C14, 11% C16, 5%CompoundC18)Alkyl* dimethyl benzylNA 1202#####NA 168Algaecide,Quaternaryammonium chloride *(61%MicrobiocideAmmoniumC12, 23% 014, 11% C16, 5%CompoundC18)Alkyl* dimethyl benzylNA 120369199NA 169Algaecide,Quaternaryammonium chlorideMicrobiocideAmmonium*(65% C12, 23% C14, 12% C16)CompoundAlkyl* dimethyl benzyl68424-85-169157NA 164Algaecide,Quaternaryammonium chlorideMicrobiocideAmmonium*(65% C12, 25% C14, 10% C16)CompoundAlkyl* dimethyl benzyl68391-01-569175NA 644Algaecide,Quaternaryammonium chlorideMicrobiocideAmmonium*(67% C12, 25% C14, 7% C16,Compound1% C18)Alkyl* dimethyl benzylNA 1204#####NA 169Algaecide,Quaternaryammonium chlorideMicrobiocideAmmonium*(67% C12, 25% C14, 7% C16,Compound1% C8, C10, and C18)Alkyl* dimethyl benzylNA 120569142NA 169MicrobiocideQuaternaryammonium chlorideAmmonium*(67% C12, 27% C14, 6% C16)CompoundAlkyl* dimethyl benzylNA 1206#####NA 169Algaecide,Quaternaryammonium chloride *(68%MicrobiocideAmmoniumC12, 25% C14, 7% C16)CompoundAlkyl* dimethyl benzylNA 120769194NA 169Algaecide,Quaternaryammonium chlorideMicrobiocideAmmonium*(90% C14, 5% C12, 5% C16)CompoundAlkyl* dimethyl benzyl68424-85-169158NA 164Algaecide,Quaternaryammonium chlorideMicrobiocideAmmonium*(93% C14, 4% C12, 3% C16)CompoundAlkyl* dimethyl benzyl68607-20-5#####NA 114Algaecide,Quaternaryammonium chloride *(95%MicrobiocideAmmoniumC16, 5% C18)CompoundAlkyl* dimethyl benzylNA 1208#####NA 169Algaecide,Quaternaryammonium chloride *(as inMicrobiocideAmmoniumfatty acids of coconut oil)CompoundAlkyl* dimethyl benzylNA 1209#####NA 169Algaecide,Quaternaryammonium chloride *(C8-18)MicrobiocideAmmoniumCompoundAlkyl* dimethyl benzyl61790-41-8#####NA 114Algaecide,Quaternaryammonium ion alkyl** amineMicrobiocideAmmonium*(C12, C14, C16) **(C10,CompoundC12, C14, C16)Alkyl* dimethyl8045-22-569109NA 624Algaecide,Quaternarydimethylbenzyl ammoniumMicrobiocideAmmoniumchloride *(50% C12, 30% C14,Compound17% C16, 3% C18)Alkyl* dimethyl ethyl134595-54-369186NA 649Algaecide,Quaternaryammonium bromide *(85%MicrobiocideAmmoniumC16, 15% C18)CompoundAlkyl* dimethyl ethyl61788-99-6#####NA 113Algaecide,Quaternaryammonium bromide *(mixedMicrobiocideAmmoniumalkyl and alkenyl groups as inCompoundfatty acids of soybean oil)Alkyl* dimethyl ethylbenzyl68956-79-669167NA 640Algaecide,Quaternaryammonium chlorideMicrobiocideAmmonium*(60% C14, 30% C16, 5% C12,Compound5% C18)Alkyl* dimethyl ethylbenzyl37335-68-569135NA 633Algaecide,QuaternaryammoniumMicrobiocideAmmoniumcyclohexylsulfamateCompound*(50% C12, 30% C14, 17% C16,3% C18)Alkyl* trimethyl ammonium1119-97-769153NA 637MicrobiocideQuaternarybromide *(95% C14, 5% C16)AmmoniumCompoundAlkyl* trimethyl ammonium112-00-5#####NA 113MicrobiocideQuaternarychloride *(70% C12, 30% C14)AmmoniumCompoundAlkyl* trimethyl ammonium68002-63-169197NA 654MicrobiocideQuaternarychloride *(70% C18, 27% C16,Ammonium3% C14)CompoundAlkyl* trimethyl ammonium68002-62-069151NA 636MicrobiocideQuaternarychloride *(90% C18, 10% C16)AmmoniumCompoundAlkyl* trimethyl ammonium61790-41-8#####NA 115MicrobiocideQuaternarychloride *(alkyl as in fattyAmmoniumacids of soybean oil)CompoundAlkyl* trimethyl ammonium61789-18-2#####NA 109MicrobiocideQuaternarychloride *(as in fatty acids ofAmmoniumcoconut oil)CompoundAlkyl* trimethyl ammonium68002-61-969139NA 634MicrobiocideQuaternarychloride *derived fromAmmoniumcottonseed oilCompoundAlkyl*-5-hydroxy-4-oxo-NA 1189#####NA 167MicrobiocideQuaternary2(4H)-pyranylmethyl dimethylAmmoniumammonium chloride *(49%CompoundC12, 17% C14, 17% C10, 10%C18, 9% C16, 8% C8)Alkyl*-N,N-bis(2-70750-47-9#####NA 114N/AQuaternaryhydroxyethyl)methylAmmoniumammonium chloride *(53%CompoundC12, 19% C14, 8.5% C16,7.0% C8, 6.5% C10, 6.0%C18)Alkyl*-N-ethyl morpholiniumNA 121369147NA 170Fungicide,Quaternaryethyl sulfate *(66% C18,AlgaecideAmmonium25% C16, 8% C18′, 1% C14)CompoundAlkyldimethylbenzylNA 1368NA 194NA 193Microbiocide,Quaternaryammonium chlorideHerbicideAmmoniumCompoundAlkyldimethylethylbenzylammoniumNA 1369NA 194NA 193Microbiocide,QuaternarychlorideHerbicideAmmoniumCompoundAlkyltrimethyl ammoniumNA 1370NA 194NA 193Microbiocide,QuaternarychlorideFungicideAmmoniumCompoundAlkyltrimethylbenzylNA 1371NA 194NA 193HerbicideQuaternaryammonium chlorideAmmoniumCompoundBenzyl dimethyl octadecyl122-19-0#####1186MicrobiocideQuaternaryammonium chlorideAmmoniumCompoundBenzyl((dodecylcarbamoyl)methyl)100-95-869159NA 638MicrobiocideQuaternarydimethyl ammoniumAmmoniumchlorideCompoundBenzyl-C12-14-alkyldimethyl134058-54-1691925069MicrobiocideQuaternaryquaternary ammoniumAmmoniumcompoundsCompoundCetyl dimethyl ethyl124-03-869156122MicrobiocideQuaternaryammonium bromideAmmoniumCompoundCetyl trimethyl ammonium57-09-069117116Microbiocide,QuaternarybromideHerbicideAmmoniumCompoundCetyl trimethyl ammonium112-02-769133NA 632MicrobiocideQuaternarychlorideAmmoniumCompoundCetylcide (95% C16, 3% C14,124-03-8691562061MicrobiocideQuaternary2% C12)AmmoniumCompoundChlormequat7003-89-6NA 216NA 215Plant GrowthQuaternaryRegulatorAmmoniumCompoundChlormequat chloride999-81-5181011512Plant GrowthQuaternaryRegulatorAmmoniumCompoundDi(alkyl* oxypropyl)dimethylNA 126169121NA 173Algaecide,Quaternaryammonium chloride *(60% C8,MicrobiocideAmmonium40% C10)CompoundDialkyl (85% C18, 15% C16)68514-95-4NA 355197Microbiocide,Quaternarydimethyl ammonium chlorideAdjuvantAmmoniumCompoundDialkyl dimethyl ammoniumNA 900NA 1725181MicrobiocideQuaternarypolynaphthyl amineAmmoniumCompoundDialkyl* dimethyl ammonium73398-64-8691362230MicrobiocideQuaternarychloride *(47% C12, 18% C14,Ammonium10% C18, 9% C10, 8% C16,Compound8% C8)Dialkyl* dimethyl ammonium73398-64-8#####NA 114MicrobiocideQuaternarychloride *(48% C12, 17% C14,Ammonium10% C18, 9% C16, 8% C8, 7%CompoundC10, 1% C6)Dialkyl* dimethyl ammonium68153-33-3#####NA 113MicrobiocideQuaternarychloride *(50% C12, 20% C14,Ammonium15% C10, 10% C16, 5% C18)CompoundDialkyl* dimethyl ammonium68910-56-569177NA 645MicrobiocideQuaternarychloride *(50% C12, 30% C14,Ammonium20% C16)CompoundDialkyl* dimethyl ammonium68002-59-569120NA 626MicrobiocideQuaternarychloride *(70% C18, 26% C16,Ammonium4% C14)CompoundDialkyl* methyl benzyl73049-75-969119NA 625Algaecide,Quaternaryammonium chloride *(60%MicrobiocideAmmoniumC14, 30% C16, 5% C18, 5%CompoundC12)Diallyl dimethyl ammonium26062-79-3#####5092AdjuvantQuaternarychloride polymersAmmoniumCompoundDibenzyldimethylammoniumNA 1440NA 213NA 213MicrobiocideQuaternarychlorideAmmoniumCompoundDicoco dimonium chloride61789-77-3691383140AdjuvantQuaternaryAmmoniumCompoundDidecyl dimethyl ammonium148788-55-069208NA 658MicrobiocideQuaternarycarbonate and didecyl dimethylAmmoniumammonium bicarbonateCompoundDidecyl dimethyl ammonium148812-65-169208NA 659MicrobiocideQuaternarycarbonate and didecyl dimethylAmmoniumammonium bicarbonateCompoundDidecyl dimethyl ammonium7173-51-5691491682Microbiocide,QuaternarychlorideFungicideAmmoniumCompoundDidecyl methyl benzyl32426-10-169170NA 642MicrobiocideQuaternaryammonium chlorideAmmoniumCompoundDihydrogenated tallow61789-81-9691503153AdjuvantQuaternarydimethyl ammoniumAmmoniummethosulfateCompoundDilauryl dimethyl ammonium3282-73-3#####NA 112MicrobiocideQuaternarybromideAmmoniumCompoundDimethyl dicoco ammoniumNA 166NA 3171945MicrobiocideQuaternarychlorideAmmoniumCompoundDimethyl dioctadecylNA 627NA 1143163AdjuvantQuaternaryammonium bentoniteAmmoniumCompoundDioctyl dimethyl ammonium5538-94-3691661710Microbiocide,QuaternarychlorideAlgaecide,AmmoniumFungicideCompoundDistearyl dimonium chloride107-64-2#####3176AdjuvantQuaternaryAmmoniumCompoundDodecyl di(2-hydroxyethyl)19379-90-969181NA 647MicrobiocideQuaternarybenzyl ammonium chlorideAmmoniumCompoundDodecyl dimethyl 2,4,5-53404-46-9#####NA 113MicrobiocideQuaternarytrimethylbenzyl ammoniumAmmoniumchlorideCompoundDodecyl dimethyl ammoniumNA 157NA 2941008MicrobiocideQuaternarychlorideAmmoniumCompoundDodecyl dimethyl benzyl196400169123NA 627Fungicide,Quaternaryammonium bromideMicrobiocideAmmoniumCompoundDodecyl dimethyl benzyl139-07-1691241167Microbiocide,Quaternaryammonium chlorideHerbicideAmmoniumCompoundDodecyl dimethyl benzyl22232-26-469128NA 629MicrobiocideQuaternaryammoniumAmmoniumcyclopentanecarboxylateCompoundDodecyl dimethyl benzylNA 1027691271446Fungicide,Quaternaryammonium naphthenateInsecticide,AmmoniumFungicideCompoundDodecyl dimethyl53466-90-3#####NA 113MicrobiocideQuaternarytrichlorobenzyl ammoniumAmmoniumchlorideCompoundDodecylbenzyl alkyl (70% C12,87175-02-8#####1038Algaecide,Quaternary30% C14) dimethyl ammoniumMicrobiocideAmmoniumchlorideCompoundDodecylbenzyl octadecyl29932-85-2#####NA 113MicrobiocideQuaternarydimethyl ammonium chlorideAmmoniumCompoundDodecylbenzyl trimethyl12379-51-069126NA 628N/AQuaternaryammonium 2-ethylhexanoateAmmoniumCompoundDodecylbenzyl trimethyl1330-85-469125918Adjuvant,Quaternaryammonium chlorideMicrobiocideAmmoniumCompoundEcolystNA 117469089NA 165Plant GrowthQuaternaryRegulatorAmmoniumCompoundEthyl dimethyl stearyl111-98-8#####NA 115MicrobiocideQuaternaryammonium bromideAmmoniumCompoundMepiquat15302-91-7NA 203NA 202Plant GrowthQuaternaryRegulatorAmmoniumCompoundMepiquat chloride24307-26-4#####2075Plant GrowthQuaternaryRegulatorAmmoniumCompoundMethyl dodecyl benzyl1399-80-069129895MicrobiocideQuaternarytrimethyl ammonium chlorideAmmoniumCompoundMethyl dodecyl benzylNA 619NA 1122678MicrobiocideQuaternarytrimethyl ammonium chlorideAmmonium80% and methylCompoundMethyl dodecyl trimethylNA 44NA 832679MicrobiocideQuaternaryammonium chlorideAmmoniumCompoundMethyl dodecyl xylene bisNA 45NA 84896MicrobiocideQuaternary(trimethyl ammonium chloride)AmmoniumCompoundMethyl trioctyl ammonium5137-55-3NA 723291AdjuvantQuaternarychlorideAmmoniumCompoundMorpholine dodecyl benzene12068-08-5#####3294Microbiocide,QuaternarysulfonateAdjuvant,AmmoniumFungicide,CompoundInsecticideN-(3,4-dichlorobenzyl)-N-102-30-7#####1129MicrobiocideQuaternarydodecyl-N,N-dimethylAmmoniumammonium chlorideCompoundN-alkyl (92% C18, 8% C16)-N-61791-34-269113986Fungicide,Quaternaryethyl morpholinium ethylMicrobiocideAmmoniumsulfateCompoundN-alkyl (soza)-N-methylNA 281NA 5503020Fungicide,Quaternarymorpholinium sulfateMicrobiocideAmmoniumCompoundN-cetyl-N-ethyl morpholinium78-21-7691131792Fungicide,Quaternaryethyl sulfateMicrobiocideAmmoniumCompoundN-Cetyl-N-ethyl morpholinium78-21-7#####NA 174FungicideQuaternaryethyl sulfateAmmoniumCompoundN-Cetyl-N-ethylmorpholinium78-21-769187NA 172FungicideQuaternaryethyl sulfateAmmoniumCompoundN-Dialkyl (60% C14, 30% C16,68424-87-3NA 3562070MicrobiocideQuaternary5% C12, 5% C18) methylAmmoniumbenzyl ammonium chlorideCompoundN-isononyl-N,N-dimethyl138698-36-9692075070MicrobiocideQuaternarydecanaminium chlorideAmmoniumCompoundOctyl decyl dimethyl32426-11-2691651709Microbiocide,Quaternaryammonium chlorideFungicideAmmoniumCompoundOctyl dodecyl dimethyl10361-16-7691901947MicrobiocideQuaternaryammonium chlorideAmmoniumCompoundOleyl dimethyl ethyl14351-44-169132NA 631MicrobiocideQuaternaryammonium bromideAmmoniumCompoundOxydiethylene bis (alkyl68607-28-3691731362MicrobiocideQuaternarydimethyl ammonium chloride),Ammoniumalkyl derived from coconut oilCompoundfatty acidsPolybromide form ofNA 11648711NA 163MicrobiocideQuaternarytrimethylbenzyl ammoniumAmmoniumresinCompoundPolyethoxypolypropoxypolyethoxyethanol-NA 128746913NA 175MicrobiocideIodine Compound,n-alkyl (54% C12,Quaternary18% C14, 9% C16, 9% C18,Ammonium5% C10, 5% C8) di(beta-Compoundhydroxyethyl) benzyl amPolymeric quaternaryNA 1463NA 217NA 216Microbiocide,Quaternaryammonium chlorideAdjuvantAmmoniumCompoundPolyquaternium-628301-34-0NA 7672818AdjuvantQuaternaryAmmoniumCompoundPolytrimethyl vinyl benzyl9017-80-5NA 1193769AdjuvantQuaternaryammonium chlorideAmmoniumCompoundQuaternium-18 bentonite68953-58-2#####2996AdjuvantQuaternaryAmmoniumCompoundSoya ethyl morpholinium61791-34-2691133453Fungicide,QuaternaryethosulfateMicrobiocideAmmoniumCompoundTetradecyl dimethyl benzyl139-08-2691071166Algaecide,Quaternaryammonium chlorideMicrobiocideAmmoniumCompoundTetraethyl ammonium77-98-54215NA 76N/AQuaternaryhydroxideAmmoniumCompound2-Mercaptobenzothiazole, zinc155-04-4517051449Fungicide,Mercaptobenzothiazole,saltMicrobiocideInorganic-Zinc5-Chloro-2-53404-93-651709NA 427Microbiocide,Mercaptobenzothiazole,mercaptobenzothiazole, zincFungicideInorganic-ZincsaltAcetic acid, copper (2+) salt142-71-2NA 6973013N/AInorganic-CopperAlkyl*-1-(2-aminoethyl)-2-NA 118846606NA 167MicrobiocideInorganic-Nickel,imidazoline acetate-nickelImidazolinesulfate complexAluminum7429-90-51111042N/AInorganicAluminum acetateNA 971NA 5483025N/AInorganicAluminum bicarbonateNA 1043NA 1403026N/AInorganicAluminum caprylate6028-57-5NA 5493027N/AInorganicAluminum chloride7446-70-0139013028N/AInorganicAluminum diacetate142-03-0NA 1133029N/AInorganicAluminum hydroxide21645-51-2NA 1292145N/AInorganicAluminum magnesium silicateNA 1018NA 1072378AdjuvantInorganicAluminum oxide1344-28-1NA 5403030N/AInorganicAluminum phosphide20859-73-866501484Fumigant,InorganicFungicide,FungicideAluminum potassium sulfate10043-67-1#####3031Herbicide,InorganicInsecticideAluminum silicate1302-76-7NA 1312379AdjuvantInorganicAluminum stearate637-12-7NA 5413032N/AInorganicAluminum sulfate10043-01-3139061415Plant GrowthInorganicRegulator,MolluscicideAmmonia7664-41-7530222Insecticide,InorganicDeer Repellent,FungicideAmmonium alum7784-26-1NA 5333037RepellentInorganicAmmonium alumNA 121698501NA 170AdjuvantInorganicAmmonium arsenate7784-44-3136012380Herbicide,Inorganic-arsenic,Insecticide,Heavy metalRodenticideAmmonium bicarbonate1066-33-7NA 5343038pH AdjustmentInorganicAmmonium bisulfate7803-63-6NA 1413039N/AInorganicAmmonium bromide12124-97-93523040N/AInorganicAmmonium carbamate1111-89-7NA 1413041N/AInorganicAmmonium carbonate506-87-6735013042Fungicide,InorganicHerbicide,Microbiocide,pH AdjustmentAmmonium chloride12125-02-9#####3043N/AInorganicAmmonium dichromate214970168305NA 607WoodInorganic-PreservativeChromium(VI),Heavy metalAmmonium ferric sulfate10138-04-2NA 5373047HerbicideInorganicAmmonium fluosilicate16919-19-075301695InsecticideInorganicAmmonium fluosilicate on62449-69-875311NA 694InsecticideInorganicsilica gelAmmonium hydroxide1336-21-653012381Fungicide, pHInorganicAdjustment,Herbicide,MicrobiocideAmmonium nitrate6484-52-2761013052Rodenticide,InorganicMicrobiocideAmmonium nitrite13446-48-576201NA 700Rodenticide,InorganicMicrobiocideAmmonium oxalate1113-38-89603891MicrobiocideInorganicAmmonium polysulfides9080-17-576701NA 707Insecticide,InorganicFungicideAmmonium sulfate7783-20-256011363Herbicide, pHInorganicAdjustmentAmmonium thiocyanate1762-95-46820025SynergistInorganicAmmonium thiosulfate7783-18-880103892Insecticide,InorganicFungicide,HerbicideAnhydrous zirconium (IV)1314-23-4790902204N/AInorganicoxideAnilinocadmium dilactate19651-91-364601NA 548N/AInorganic-Cadmium,Heavy metalArsenic7440-38-2NA 121710Herbicide,Inorganic-arsenic,Insecticide,Heavy metalRodenticideArsenic acid7778-39-4680140Herbicide,Inorganic-arsenic,Insecticide,Heavy metalRodenticideArsenic disulfide56320-22-06901NA 98Herbicide,Inorganic-arsenic,Insecticide,Heavy metalRodenticideArsenic pentoxide1303-28-26802631Fungicide,Inorganic-arsenic,Insecticide,Heavy metalRodenticide,HerbicideArsenic sulfide12612-21-46901NA 99Herbicide,Inorganic-arsenic,Insecticide,Heavy metalRodenticideArsenic trioxide1327-53-3700142Herbicide,Inorganic-arsenic,Insecticide,Heavy metalRodenticideArsenic trisulfide1303-33-96901NA 97Herbicide,Inorganic-arsenic,Insecticide,Heavy metalRodenticideArsonic acid, ammonium salt58829-95-1#####NA 105Herbicide,Inorganic-arsenic,Insecticide,Heavy metalWoodPreservativeAsbestos1332-21-4993012398InsecticideInorganicBarium carbonate513-77-975013060N/AInorganicBarium chloride10361-37-2NA 1413061N/AInorganicBarium fluosilicate17125-80-375302NA 688InsecticideInorganicBarium metaborate13701-59-211101973FungicideInorganicBarium nitrate10022-31-8NA 186NA 185RepellentInorganicBarium polysulfide50864-67-076704NA 709Insecticide,InorganicFungicideBarium sulfate7727-43-775022411N/AInorganicBasic copper arsenate16102-92-4#####NA 132Herbicide,Inorganic-arsenic,Insecticide,Heavy metal,RodenticideInorganic-CopperBasic lead silicate53466-66-348003NA 417N/AInorganic-Lead,Heavy metalBentonite1302-78-9NA 4961399AdjuvantInorganicBlast furnace slagNA 239NA 4772425N/AInorganicBorax1303-96-41110279Insecticide,InorganicHerbicideBordeaux mixtureNA 240NA 47880FungicideInorganic-CopperBoric acid10043-35-311001769InsecticideInorganicBoric acid(H4B6O11), zinc12447-61-9#####5094FungicideInorganic-Zincsalt(1:2)Boric oxide1303-86-2110022090InsecticideInorganicBoron7440-42-8#####2426N/AInorganicBoron sodium oxide12179-04-311110NA 116InsecticideInorganic(B4Na2O7), pentahydrateBromine7726-95-687012296MicrobiocideInorganicBromine chloride13863-41-7205042323MicrobiocideInorganicCadmium7440-43-9NA 4602438N/AInorganic-Cadmium,Heavy metalCadmium carbonate513-78-01290193N/AInorganic-Cadmium,Heavy metalCadmium chloride10108-64-21290294N/AInorganic-Cadmium,Heavy metalCadmium cocoate72869-63-7NA 4593085N/AInorganic-Cadmium,Heavy metalCadmium oxide1306-19-0#####NA 130N/AInorganic-Cadmium,Heavy metalCadmium perborateNA 969NA 4613086N/AInorganic-Cadmium,Heavy metalCadmium sebacate93949912903699N/AInorganic-Cadmium,Heavy metalCadmium succinate141-00-41290492N/AInorganic-Cadmium,Heavy metalCadmium sulfate10124-36-412905NA 123N/AInorganic-Cadmium,Heavy metalCadmium yellow pigmentsNA 967NA 4482439N/AInorganic-Cadmium,Heavy metalCalcareous shaleNA 230NA 4493595N/AInorganicCalcium arsenate7778-44-11350196Herbicide,Inorganic-arsenic,Insecticide,Heavy metalRodenticide,MolluscicideCalcium arsenite53404-59-413602NA 129Herbicide,Inorganic-arsenic,Insecticide,Heavy metalRodenticideCalcium carbide75-20-7NA 4501571RepellentInorganicCalcium carbonate471-34-1735021007pH Adjustment,InorganicFungicide,Microbiocide,HerbicideCalcium carbonate, treatedNA 968NA 4512440pH Adjustment,InorganicFungicide,Microbiocide,HerbicideCalcium chlorate10137-74-373302NA 682Defoliant,InorganicHerbicide,MicrobiocideCalcium chloride10043-52-475605920Fungicide,InorganicHerbicide,Insecticide,Microbiocide,Molluscicide,Dessicant, PlantGrowthRegulatorCalcium cyanide592-01-874001176RodenticideInorganicCalcium hydroxide1305-62-07560199pH Adjustment,InorganicFungicide,Microbiocide,HerbicideCalcium hypochlorite7778-54-314701326Algaecide,InorganicWaterTreatmentCalcium nitrite13780-06-876202NA 701Rodenticide,InorganicMicrobiocideCalcium phosphate10103-46-5NA 195NA 195RodenticideInorganicCalcium phosphate, tribasic7758-87-4764011607Rodenticide,InorganicFungicide,Herbicide,MicrobiocideCalcium silicate10101-39-0726071908Insecticide,InorganicAdjuvant,Fungicide,MicrobiocideCalcium sulfate7778-18-956022442Insecticide,InorganicHerbicideCalcium sulfate dihydrate10101-41-4203NA 163Insecticide,InorganicHerbicideCalcium thiosulfate10124-41-180101930Insecticide,InorganicFungicide,HerbicideCalcium-zinc LN 193NA 653NA 1203871N/AInorganic-Zinc(complex)Calomel10112-91-152201100FungicideInorganic-Mercury,Heavy metalCarbon7440-44-016001712WaterInorganicTreatment,RodenticideCarbon black pigment1333-86-4NA 4422445DyeInorganicCarbon dioxide124-38-9166012207Fumigant,InorganicInsecticide,RodenticideCarbon disulfide75-15-016401108Fumigant,InorganicSolvent,Breakdownproduct,NematicideChlorinated trisodium56802-99-4#####2214WaterInorganicphosphate (prior TSP &Treatmentsodium hypochlorite)Chlorine7782-50-520501131Microbiocide,InorganicWaterTreatmentChlorine dioxide10049-04-4205032053Microbiocide,InorganicWaterTreatmentChlorophyllin11006-34-1NA 191NA 190Fungicide,Inorganic-Copper,MicrobiocideBotanicalChromated zinc chlorideNA 1026878011187Insecticide,Inorganic-Herbicide,Chromium(VI),MicrobiocideInorganic-Zinc,Heavy metalChromic acetate1066-30-421102NA 172WoodInorganic-PreservativeChromium(VI),Heavy metalChromic acid7738-94-5211011188WoodInorganic-PreservativeChromium(VI),Heavy metalChromic oxide1308-38-921103NA 173WoodInorganic-PreservativeChromium(VI),Heavy metalChromium dioxide12018-01-8NA 4112470N/AInorganicCobaltous sulfate10124-43-3NA 1143110N/AInorganicCopper7440-50-822501714FungicideInorganic-CopperCopper (from triethanolamine82027-59-624403NA 198AlgaecideInorganic-Coppercomplex)Copper 2-ethylhexanoate22221-10-9412012235FungicideInorganic-CopperCopper 3-phenylsalicylate125068223801NA 191N/AInorganic-CopperCopper 8-quinolinoleate10380-28-624002159Fungicide,Inorganic-CopperMicrobiocideCopper abietate10248-55-223301NA 184FungicideInorganic-CopperCopper acetate83163244002147FungicideInorganic-CopperCopper ammonium acetateNA 1544NA 225NA 225FungicideInorganic-CopperCopper ammonium carbonate33113-08-5227031762FungicideInorganic-CopperCopper ammonium complex16828-95-8227023550FungicideInorganic-CopperCopper arsenate10103-61-422801NA 178Herbicide,Inorganic-arsenic,Insecticide,Heavy metal,RodenticideInorganic-CopperCopper arsenite10290-12-722401NA 177Herbicide,Inorganic-arsenic,Insecticide,Heavy metal,RodenticideInorganic-CopperCopper as elemental from50376-91-524404NA 199N/AInorganic-Coppercopper - etidronic acid complexCopper beta cyclodextrinNA 1366NA 193NA 193FungicideInorganic-CopperhydroxideCopper bronze powder7440-50-8225011457AntifoulantInorganic-CopperCopper carbonate, basic1184-64-12290160Fungicide,Inorganic-CopperAlgaecide,InsecticideCopper chloride (anhydrous)1344-67-823802NA 192N/AInorganic-CopperCopper chloride (dihydrate)10125-13-023701NA 190N/AInorganic-CopperCopper citrate10402-15-0440051406N/AInorganic-CopperCopper citrate chelateNA 961NA 3873547N/AInorganic-CopperCopper complex with ammonia67989-88-2#####NA 130FungicideInorganic-Copperand ethylene diaminetetraacetateCopper cresylate12379-42-923001NA 181FungicideInorganic-CopperCopper53404-24-341202NA 349N/AInorganic-Copperdehydroabietylammonium 2-ethylhexanoateCopper dihydrazinium sulfate33271-65-750504753N/AInorganic-CopperCopper ethanolamine complex14215-52-224409NA 201AlgaecideInorganic-CopperCopper ethanolamineNA 1044NA 1463551AlgaecideInorganic-Coppercomplexes, mixedCopper ethylenediamine13426-91-0244073549HerbicideInorganic-CoppercomplexCopper gluconate chelate814-91-5233053548N/AInorganic-CopperCopper hydrazinium sulfate53433-02-650501NA 418FungicideInorganic-CopperCopper hydroxide20427-59-223401151Fungicide,Inorganic-CopperMicrobiocide,NematicideCopper hydroxide - NA 1017NA 1051826N/AInorganic-Coppertriethanolamine complexCopper isodecanoate84082-88-241221NA 354N/AInorganic-CopperCopper isononanoate72915-82-341211NA 352N/AInorganic-CopperCopper isooctanoate88859-94-341204NA 350N/AInorganic-CopperCopper lactate16039-52-423302NA 185N/AInorganic-CopperCopper linoleate7721-15-5233031110N/AInorganic-CopperCopper metaborate39290-85-222802NA 179N/AInorganic-CopperCopper monoethanolamineNA 960NA 3843552N/AInorganic-CoppercomplexCopper naphthenate1338-02-923102153WoodInorganic-CopperPreservative,Insecticide,Fungicide, Dogand CatRepellentCopper naphthenate1338-02-96000NA 172WoodInorganic-CopperPreservative,Insecticide,Fungicide, Dogand CatRepellentCopper naphthenate1338-02-96300NA 172WoodInorganic-CopperPreservative,Insecticide,Fungicide, Dogand CatRepellentCopper nitroacetate22221-12-123201NA 183N/AInorganic-CopperCopper octanoate20543-04-8233065225FungicideInorganic-CopperCopper oleate10402-16-123304154FungicideInorganic-CopperCopper oxide (ic)1317-38-0424012231Fungicide,Inorganic-CopperInsecticideCopper oxide (ous)1317-39-125601175Fungicide,Inorganic-CopperInsecticideCopper oxychloride1332-40-78001156FungicideInorganic-CopperCopper oxychloride1332-65-623501NA 186FungicideInorganic-Copper(Cu2Cl(OH)3)Copper oxychloride sulfate8012-69-923503158FungicideInorganic-CopperCopper oxysulfate12158-97-323504NA 188N/AInorganic-CopperCopper oxysulfate82010-79-523504NA 189N/AInorganic-CopperCopper pentachlorophenate15773-35-063011NA 512WoodChlorinated Phenol,Preservative,Inorganic-CopperMicrobiocide,Algaecide,FungicideCopper phosphate10103-48-722902NA 180N/AInorganic-CopperCopper phthalocyanine147-14-8NA 3812479DyeInorganic-CopperCopper pyrophosphate10102-90-669701NA 663N/AInorganic-CopperCopper salts of fatty and rosin9007-39-023104155FungicideInorganic-CopperacidsCopper salts of the acids of tall61789-22-823103NA 182N/AInorganic-CopperoilCopper silicate1344-72-524301NA 197N/AInorganic-CopperCopper sodium sulfate-NA 1023NA 121755N/AInorganic-Copperphosphate complexCopper sulfate (anhydrous)7758-98-7244081778Fungicide,Inorganic-CopperAlgaecide,MolluscicideCopper sulfate (basic)1344-73-68101162Fungicide,Inorganic-CopperAlgaecide,MolluscicideCopper sulfate (pentahydrate)7758-99-824401161Algaecide,Inorganic-CopperFungicide,Insecticide,WaterTreatment,Molluscicide,NematicideCopper sulfate ethyleneNA 1036NA 1322480N/AInorganic-CopperdiamineCopper sulfate, monohydrate10257-54-2244021789Fungicide,Inorganic-CopperAlgaecide,MolluscicideCopper sulfate, tri-basicNA 1384NA 195NA 194Herbicide,Inorganic-CopperAlgaecide,Fungicide,WaterTreatmentCopper triethanolamine68027-59-6NA 1251615AlgaecideInorganic-CoppercomplexCopper-zinc chromate complex1344-74-721003163Fungicide,Inorganic-WoodChromium(VI),PreservativeInorganic-Zinc,Heavy metal,Inorganic-CopperCopper-zinc sulfate complex55072-57-68102164FungicideInorganic-Zinc,Inorganic-CopperCopper-zinc sulfate complex,NA 959NA 3821751FungicideInorganic-Zinc,monohydrateInorganic-CopperCrag turf fungicide 53112001-20-621006NA 171FungicideInorganic-Cadmium,(Cd—Cu—Ca—Zn-Chromate)Inorganic-Chromium(VI),Inorganic-Zinc,Heavy metalCryolite15096-52-375101173InsecticideInorganicCuprammoniumNA 1382NA 195NA 194FungicideInorganic-CopperCupric acetoarsenite12002-03-8226012485WoodInorganic-arsenic,PreservativeHeavy metal,Inorganic-CopperCupric ferric subsulfate12168-20-642402NA 365MolluscicideInorganic-CoppercomplexCupric fluosilicate12062-24-775309NA 692InsecticideInorganic-CopperCupric gluconate527-09-3244053117FungicideInorganic-CopperCupric nitrate3251-23-8761023118N/AInorganic-CopperCuprous and cupric oxide,82010-82-042403NA 366N/AInorganic-CoppermixedCuprous chloride (Cu2Cl2)7758-89-6#####5597FungicideInorganic-CopperCuprous iodide7681-65-4#####NA 902N/AInorganic-CopperCuprous sulfide22205-45-4#####NA 124N/AInorganic-CopperCuprous thiocyanate1111-67-7256022108MicrobiocideInorganic-CopperDevice (swimming poolNA 1504NA 222NA 222AlgaecideInorganic-Copperalgaecide, copper generating)no guarantee requiredDevice (swimming poolNA 1505NA 222NA 222AlgaecideInorganicalgaecide, peroxide) noguarantee requiredDevice (swimming poolNA 1506NA 222NA 222AlgaecideInorganicalgaecide, salt in pool) noguarantee requiredDi-potassium salts of13492-26-776416NA 704Fungicide,Inorganicphosphorous acidMicrobiocideDiammonium phosphate7783-28-0NA 819654Insecticide,InorganicFungicide,Herbicide,Microbiocide,pH AdjustmentDiatomaceous earth7631-86-972605195Insecticide,InorganicMolluscicideDiatomaceous earth, otherNA 1155NA 17390195Insecticide,InorganicrelatedMolluscicideDihydrogen54453-03-124406NA 200N/AInorganic-Copper{ethylenediaminetetraacetato(4-)}cuprate(2-)Disodium EDTA-copper14025-15-1NA 2963173N/AInorganic-CopperDisodium mono ethanolamine53404-45-8764101608pH Adjustment,InorganicphosphateFungicide,Herbicide,MicrobiocideDisodium octaborate12008-41-2111075053InsecticideInorganicanhydrousDisodium octaborate12280-03-4111031800Insecticide,InorganictetrahydrateHerbicideDisodium phosphate7558-79-4764032534pH Adjustment,InorganicFungicide,Herbicide,MicrobiocideEDTA diammonium copper7379-26-2391171613AlgaecideInorganic-CoppersaltEDTA, copper complex12276-01-6391051135AlgaecideInorganic-CopperEDTA, disodium zinc salt14025-21-9NA 2743189N/AInorganic-ZincFatty acid* - silver complex24927-67-172505NA 675Microbiocide,Inorganic-Silver,*(100% C8)Fungicide,Heavy metalHerbicideFeldspar68476-25-5NA 1183656N/AInorganicFerric chloride7705-08-0349013205HerbicideInorganicFerric oxide1332-37-2NA 1043206N/AInorganicFerric sulfate (anhydrous)10028-22-5349021811HerbicideInorganicFerrous ammonium sulfate10045-89-3505061307HerbicideInorganicFerrous ammonium sulfate7783-85-950509NA 421HerbicideInorganichexahydrateFerrous sulfate7720-78-7NA 120289Herbicide,InorganicMolluscicideFerrous sulfate (monohydrate)17375-41-6505071812Herbicide,InorganicDefoliantFerrous sulfate heptahydrate7782-63-0505021687HerbicideInorganicGraniteNA 105NA 2093663N/AInorganicGraphite7782-42-5NA 2103217N/AInorganicHydrated lime1302-62-0NA 1943669pH Adjustment,InorganicFungicide,Microbiocide,HerbicideHydriodic acid10034-85-246912NA 408N/AInorganicHydrocyanic acid74-90-845801NA 388FumigantInorganicHydrofluoric acid7664-39-345601NA 387N/AInorganicHydrogen chloride7647-01-045901329FumigantInorganicFungicide,Nematicide, pHAdjustment,HerbicideHydrogen peroxide7722-84-15951794Microbiocide,InorganicFungicide,Herbicide,RodenticideHydrogen sulfide2147416NA 227NA 227BreakdownInorganicproductHydrophosphorous acidNA 95NA 1892600N/AInorganicHydroxymercury cresol12379-66-746001NA 390MicrobiocideInorganic-Mercury,Heavy metal, PhenolsHypochlorous acid7790-92-3#####NA 110WaterInorganicTreatment,Microbiocide,pH AdjustmentHypoiodous acid14332-21-9#####NA 153N/AInorganicInorganic phosphateNA 940NA 1693671pH Adjustment,InorganicFungicide,Herbicide,MicrobiocideIodic acid7782-68-546902NA 405N/AInorganicIodine7553-56-246905718Microbiocide,InorganicFungicide,HerbicideIron7439-89-6NA 121655N/AInorganicIron oxide (Fe2O3)1309-37-1#####NA 870HerbicideInorganicIron oxide pigmentNA 942NA 1752618DyeInorganicIron phosphate10045-86-0349035014MolluscicideInorganicKaolin1332-58-7#####2629Insecticide,InorganicAdjuvant,Fungicide,MicrobiocideLauric acid, barium cadmium15337-60-7NA 1183676AdjuvantInorganic-Cadmium,saltHeavy metalLead7439-92-1NA 1342638N/AInorganic-Lead,Heavy metalLead acetate301-04-248001NA 415N/AInorganic-Lead,Heavy metalLead arsenate7784-40-913503353Herbicide,Inorganic-arsenic,Insecticide,Inorganic-lead,RodenticideHeavy metalLead arsenate, basic1327-31-713502354Herbicide,Inorganic-arsenic,Insecticide,Inorganic-lead,RodenticideHeavy metalLead metasilicateNA 938NA 1381106N/AInorganic-Lead,Heavy metalLead monoxide10190-55-3NA 1231271N/AInorganic-Lead,Heavy metalLead naphthenate61790-14-5480043296N/AInorganic-Lead,Heavy metalLignin sulfonic acid, copperNA 933NA 1261925N/AInorganic-CoppersaltLignin sulfonic acid, zinc saltNA 1014NA 1021768N/AInorganic-ZincLignin sulfonic acid, zinc,NA 1030NA 1261771N/AInorganic-Zincmanganese & iron saltsLime1305-78-875604977pH Adjustment,InorganicFungicide,Herbicide,MicrobiocideLime phosphateNA 1432NA 200NA 199Plant GrowthInorganicRegulatorLime-sulfur1344-81-676702358Insecticide,InorganicFungicideLitharge1317-36-848002NA 416N/AInorganic-Lead,Heavy metalLithium carbonate554-13-2NA 1193924pH Adjustment,InorganicFungicide,Microbiocide,HerbicideLithium chloride7447-41-8#####5318N/AInorganicLithium hydroxide1310-65-2NA 1433267pH Adjustment,InorganicFungicide,Herbicide,MicrobiocideLithium hypochlorite13840-33-014702922Microbiocide,InorganicWaterTreatmentLithium perchlorate2150251NA 1153268N/AInorganicMagnesium aluminum1327-43-175310NA 693InsecticideInorganicfluosilicateMagnesium arsenate10103-50-113504NA 126Herbicide,Inorganic-arsenic,Insecticide,Heavy metalRodenticideMagnesium carbonate546-93-0735032654pH Adjustment,InorganicFungicide,Microbiocide,HerbicideMagnesium chlorate10326-21-3#####NA 155Defoliant,InorganicHerbicide,MicrobiocideMagnesium chloride7786-30-313902365Molluscicide,InorganicHerbicide,Insecticide,MicrobiocideMagnesium chloride,7791-18-6NA 1102655Molluscicide,InorganichexahydrateHerbicide,Insecticide,MicrobiocideMagnesium fluosilicate16949-65-875304NA 689InsecticideInorganicMagnesium limeNA 931NA 1113679N/AInorganicMagnesium nitrate10377-60-3NA 1153269Rodenticide,InorganicMicrobiocideMagnesium oxide1309-48-492352656pH Adjustment,InorganicFungicide,Herbicide,MicrobiocideMagnesium phosphide12057-74-8665042085Fumigant,InorganicRodenticideMagnesium silicate1343-88-072601NA 680Insecticide,InorganicAdjuvant,Fungicide,MicrobiocideMagnesium silicate, hydrous14807-96-6NA 1132658AdjuvantInorganicMagnesium sulfate7487-88-9505031339Molluscicide,InorganicAdjuvantMalachite (copper equivalent1319-53-5#####NA 155N/AInorganic-Copper57%)Mancozeb223310014504211FungicideDithiocarbamate,Inorganic-ZincManeb and nickel sulfate8005-46-7#####NA 158FungicideDithiocarbamate,hexahydrate (014505 + 050505)Inorganic-NickelManganese (II) oxide1344-43-0NA 1043274N/AInorganicManganese arsenate7784-38-513506NA 127Herbicide,Inorganic-arsenic,Insecticide,Heavy metalRodenticideManganese carbamateNA 55NA 1033273N/AInorganicManganese sulfate7785-87-7NA 105658N/AInorganicManganous oxide1344-43-0NA 1433275N/AInorganicMercuric acetate1600-27-752104NA 441N/AInorganic-Mercury,Heavy metalMercuric chloride7487-94-752001372FungicideInorganic-Mercury,Heavy metalMercuric dimethyl15415-64-234808709MicrobiocideInorganic-Mercury,dithiocarbamateHeavy metal,DithiocarbamateMercuric iodide7774-29-052003NA 438N/AInorganic-Mercury,Heavy metalMercuric oleate1191-80-6521053276N/AInorganic-Mercury,Heavy metalMercuric oxide21908-53-252102955FungicideInorganic-Mercury,Heavy metalMercury7439-97-652301NA 26N/AInorganic-Mercury,Heavy metalMercury naphthenate1336-96-552101NA 439WoodInorganic-Mercury,Preservative,Heavy metalInsecticide,FungicideMercury pentanedione14024-55-652103NA 440N/AInorganic-Mercury,Heavy metalMercury phenate588-66-952106NA 442N/AInorganic-Mercury,Heavy metalMetallic silver7440-22-4725012125Microbiocide,Inorganic-Silver,Fungicide,Heavy metalHerbicideMetiram9006-42-214601493FungicideDithiocarbamate,Inorganic-ZincMica12003-33-2NA 1183690N/AInorganicMixed copper chelates orNA 1437NA 213NA 212FungicideInorganic-Coppercomplex blend of copper saltsMolybdenum7439-98-7NA 1523903N/AInorganicMolybdic acid, disodium salt7631-95-0NA 1352690N/AInorganicMono-potassium salts of13977-65-676416NA 705Fungicide,Inorganicphosphorous acidMicrobiocideMonosodium phosphate7558-80-7764091772pH Adjustment,InorganicFungicide,Herbicide,MicrobiocideN-(2-hydroxyethyl) ethyleneNA 1025NA 1221130N/AInorganic-Copperdiamine triacetic acid, coppersaltNeodecanoic acid, copper salt50315-14-597503NA 854N/AInorganic-CopperNickel7440-02-0NA 121762N/AInorganic-NickelNickel diethyl hexyl acidNA 928NA 533696N/AInorganic-Nickelphosphate complexNickel sulfate (anhydrous)7786-81-450508NA 420FungicideInorganic-NickelNickel sulfate hexahydrate10101-97-050505NA 419FungicideInorganic-NickelNitric acid7697-37-245951NA 389N/AInorganicNitric acid technical7697-37-2NA 472703N/AInorganicNitrogen trichloride10025-85-1NA 502705N/AInorganicNitrogen, liquified7727-37-9#####2267InsecticideInorganicNitrous oxide10024-97-2NA 1153302N/AInorganicNoury dry cobalt 12%NA 21NA 332712N/AInorganicNuxtra manganese 12%NA 746NA 1352719N/AInorganiccatalysto-Phenylphenol, alkyl* amine-82010-74-064107NA 533MicrobiocidePhenols, Inorganic-zinc salt of *(100% C18)ZincOxalic acid144-62-79601899MicrobiocideInorganicOzone10028-15-6NA 228NA 228WaterInorganicTreatment,Microbiocidep-tert-53433-01-552002NA 437MicrobiocideInorganic-Mercury,OctylphenoxyethoxyethylHeavy metaldimethyl benzyl ammoniummercuric chlorideParis green12002-03-822601460WoodInorganic-Arsenic,PreservativeInorganic-Copper,Heavy metalPenta potassium triphosphate13845-36-8764123319N/AInorganicPentachlorophenol, zinc salt2917-32-063008NA 510WoodChlorinated Phenol,Preservative,Inorganic-ZincMicrobiocide,Algaecide,FungicidePerboric acid, sodium saltNA 1160NA 1745452InsecticideInorganicPerboric acid, sodium salt,10332-33-9111055052InsecticideInorganicmonohydratePerchloric acid, calcium salt13477-36-6NA 6703321N/AInorganicPerliteNA 756NA 1362767N/AInorganicPeroxyacetic acid79-21-0632012291Microbiocide,InorganicFungicide,Herbicide,RodenticidePeroxydisulfuric acid13445-49-363601NA 524N/AInorganicPhosphine7803-51-2665003541Fumigant,InorganicInsecticidePhosphoric acid7664-38-276001871Fungicide, pHInorganicAdjustment,Herbicide,MicrobiocidePhosphoric acid, disodium salt,10028-24-776415NA 703pH Adjustment,InorganicdihydrateFungicide,Herbicide,MicrobiocidePhosphoric acid,7778-77-0764132777pH Adjustment,Inorganicmonopotassium saltFungicide,Herbicide,MicrobiocidePhosphoric acid, trisodium salt56802-99-4#####3851WaterInorganic(chlorinated)TreatmentPhosphorous acid13598-36-276002NA 699Fungicide,InorganicMicrobiocidePhosphorus7723-14-066502513N/AInorganicPhosphorus pentasulfide1314-56-3NA 6402778N/AInorganicPolyoxin D zinc salt146659-78-1#####NA 129FungicideInorganic-ZincPotassium aluminum silicateNA 996NA 7743344AdjuvantInorganicPotassium aluminum sulfate7784-24-9NA 7753345Insecticide,InorganicHerbicidePotassium arsenite10124-50-213605NA 131Herbicide,Inorganic-arsenic,Insecticide,Heavy metalRodenticidePotassium arsenite13464-35-213605NA 132Herbicide,Inorganic-arsenic,Insecticide,Heavy metalRodenticidePotassium azide20762-60-1#####NA 898N/AInorganicPotassium bicarbonate298-14-6735085037FungicideInorganicPotassium bifluoride7789-29-975203NA 687N/AInorganicPotassium bisulfate7646-93-756051860pH Adjustment,InorganicFungicide,Herbicide,MicrobiocidePotassium bromide2138164139031090MicrobiocideInorganicPotassium carbonate584-08-7735041620pH Adjustment,InorganicFungicide,Microbiocide,HerbicidePotassium chlorate696616733033347Defoliant,InorganicHerbicide,MicrobiocidePotassium chloride7447-40-713904NA 137N/AInorganicPotassium chromate7789-00-668301700WoodInorganic-PreservativeChromium(VI),Heavy metalPotassium cyanate590-28-368002NA 600N/AInorganicPotassium cyanide151-50-8#####497RodenticideInorganicPotassium dichromate7778-50-9683022167WoodInorganic-PreservativeChromium(VI)Potassium hexafluoroarsenate17029-22-0#####NA 160N/AInorganic-arsenic,Heavy metalPotassium hydroxide1310-58-3756021306pH Adjustment,InorganicFungicide,Herbicide,MicrobiocidePotassium hypochlorite7778-66-7#####NA 110MicrobiocideInorganicPotassium iodate213825675703NA 696N/AInorganicPotassium iodate (KH(IO3)2)13455-24-875704NA 697N/AInorganicPotassium iodide7681-11-0757011003MicrobiocideInorganicPotassium mercuric iodide7783-33-752107NA 443N/AInorganic-Mercury,Heavy metalPotassium monopersulfate10361-76-9#####NA 104N/AInorganicPotassium nitrate7757-79-176103726Rodenticide,InorganicMicrobiocidePotassium nitrite7758-09-0762033356Rodenticide,InorganicMicrobiocidePotassium permanganate7722-64-768501498Fungicide,InorganicAlgaecide,Molluscicide,MicrobiocidePotassium peroxydisulfate7727-21-1636021028Microbiocide,InorganicFungicide,Herbicide,RodenticidePotassium peroxymonosulfate10058-23-8636041859Microbiocide,InorganicFungicide,Herbicide,RodenticidePotassium peroxymonosulfate37222-66-563607NA 527Microbiocide,Inorganicsulfate,Fungicide,(2KHSO5.KHSO4.K2SO4)Herbicide,RodenticidePotassium peroxymonosulfate70693-62-863607NA 528Microbiocide,Inorganicsulfate,Fungicide,(2KHSO5.KHSO4.K2SO4)Herbicide,RodenticidePotassium phosphate7778-53-2764073358pH Adjustment,InorganicFungicide,Herbicide,MicrobiocidePotassium phosphate, dibasic2138438#####3359pH Adjustment,InorganicFungicide,Herbicide,MicrobiocidePotassium phosphiteNA 1565NA 2295766FungicideInorganicPotassium phosphonateNA 1563NA 227NA 227FungicideInorganic(phosphorous acid equivalent)Potassium polysulfide37199-66-976703NA 708Insecticide,InorganicFungicidePotassium pyrophosphate7320-34-5764081175pH Adjustment,InorganicFungicide,Herbicide,MicrobiocidePotassium silicate1312-76-1726062826Insecticide,InorganicAdjuvant,Fungicide,MicrobiocidePotassium sulfate7778-80-556033362Insecticide,InorganicHerbicidePotassium sulfite10117-38-1NA 7853364FungicideInorganicPotassium tetraborate1332-77-0NA 1443365InsecticideInorganicPotassium tetrathionate13932-13-375903NA 698Insecticide,InorganicHerbicidePotassium thiocyanate333-20-068201NA 605InsecticideInorganicPotassium thiosulfate10233-00-880102NA 773Insecticide,InorganicFungicide,HerbicidePotassium triiodide12298-68-9469175066MicrobiocideInorganicPropineb12071-83-9#####NA 155Fungicide,Dithiocarbamate,MicrobiocideInorganic-ZincPumice1332-09-8NA 1503777N/AInorganicQuartz sandNA 1363NA 193NA 192InsectInorganicRepellentRock powderNA 1375NA 194NA 194N/AInorganicSelenium and compounds7782-49-272001NA 31N/AInorganicSelenium disulfide7488-56-472003NA 673N/AInorganicShaleNA 459NA 8213794N/AInorganicSilica aerogel63231-67-472602529Insecticide,InorganicAdjuvant,Fungicide,MicrobiocideSilica gel63231-67-4726023557Insecticide,InorganicAdjuvant,Fungicide,MicrobiocideSilica hydrateNA 461NA 8242853N/AInorganicSilica, crystalline-fused60676-86-0NA 8232851N/AInorganicSilica, crystalline-quartz14808-60-7NA 1382852N/AInorganicSilicic acid1343-98-2NA 8253556N/AInorganicSilicon dioxide fresh waterNA 1524NA 223NA 223InsecticideInorganicfossilsSilver acetate563-63-372507NA 676Microbiocide,Inorganic-Silver,Fungicide,Heavy metalHerbicideSilver carbonate534-16-772509NA 678Microbiocide,Inorganic-Silver,Fungicide,Heavy metalHerbicideSilver chloride7783-90-6725062324Microbiocide,Inorganic-Silver,Fungicide,Heavy metalHerbicideSilver copper zeolite130328-19-7#####NA 110MicrobiocideInorganic-Silver,Heavy metal,Inorganic-CopperSilver fluoride7775-41-972502NA 674Microbiocide,Inorganic-Silver,Fungicide,Heavy metalHerbicideSilver iodide, colloidal7783-96-2NA 1241556Microbiocide,Inorganic-Silver,Fungicide,Heavy metalHerbicideSilver nitrate7761-88-8725032856Microbiocide,Inorganic-Silver,Fungicide,Heavy metalHerbicide,Plant GrowthRegulatorSilver orthophosphate7784-09-072510NA 679Microbiocide,Inorganic-Silver,(Ag3PO4)Fungicide,Heavy metalHerbicideSilver oxide (Ag4O4)1301-96-8#####NA 111Microbiocide,Inorganic-Silver,Fungicide,Heavy metalHerbicideSilver oxide (Ag4O4)155645-89-9#####NA 111Microbiocide,Inorganic-Silver,Fungicide,Heavy metalHerbicideSilver sodium hydrogenNA 116672560NA 164MicrobiocideInorganic-Silver,zirconium phosphateHeavy metal(Ag0.18Na0.57H0.25Zr2(PO4)3)Silver thiocyanate1701-93-568203NA 606Microbiocide,Inorganic-Silver,Fungicide,Heavy metalHerbicideSilver thiuronium acrylate copolymer53404-00-572701NA 681Microbiocide,Inorganic-Silver,Fungicide,Heavy metalHerbicideSilver zeolite130328-18-6#####NA 125MicrobiocideInorganic-Silver,Heavy metalSilver zinc zeolite130328-20-0#####NA 111MicrobiocideInorganic-Silver,Inorganic-Zinc,Heavy metalSilver, ionic14701-21-4NA 1695150Microbiocide,Inorganic-Silver,Fungicide,Heavy metalHerbicideSoapstoneNA 465NA 8293797N/AInorganicSodium7440-23-5NA 8302858N/AInorganicSodium acid phosphate7558-80-7764091413pH Adjustment,InorganicFungicide,Herbicide,MicrobiocideSodium acid pyrophosphate7758-16-9NA 8313381pH AdjustmentInorganicSodium aluminate1302-42-7NA 1453382N/AInorganicSodium aluminum fluosilicate53404-77-675308NA 691InsecticideInorganicSodium aluminum phosphate7785-88-8NA 8323383N/AInorganicSodium arsenate13464-38-513505283Herbicide,Inorganic-arsenic,Insecticide,Heavy metalRodenticideSodium arsenite7784-46-513603534Herbicide,Inorganic-arsenic,Insecticide,Heavy metalRodenticide,FungicideSodium azide26628-22-8#####NA 897N/AInorganicSodium bicarbonate144-55-8735051134Fungicide, pHInorganicAdjustmentSodium bichromate dihydrate7789-12-0683063980WoodInorganic-PreservativeChromium(VI),InorganicSodium bifluoride1333-83-1752013385N/AInorganicSodium binoxalate1186-49-89602NA 110MicrobiocideInorganicSodium bisulfate7681-38-173201905pH Adjustment,InorganicFungicide,Herbicide,MicrobiocideSodium bisulfite7631-90-578201547pH Adjustment,InorganicFungicideSodium borohydride16940-66-2NA 8343387N/AInorganicSodium bromate7789-38-013908NA 138N/AInorganicSodium bromide7647-15-6139071103Molluscicide,InorganicHerbicide,Insecticide,MicrobiocideSodium carbonate497-19-873506854pH Adjustment,InorganicFungicide,Microbiocide,HerbicideSodium chlorate214459173301536Defoliant,InorganicHerbicide,MicrobiocideSodium chloride7647-14-513905721Molluscicide,InorganicHerbicide,Insecticide,MicrobiocideSodium chlorite7758-19-2205022148Microbiocide,InorganicWaterTreatmentSodium chromate2144646683031241WoodInorganic-PreservativeChromium(VI),Heavy metalSodium cyanide143-33-974002688RodenticideInorganicSodium dichromate10588-01-9683043395WoodInorganic-PreservativeChromium(VI),Heavy metalSodium dihydrogen phosphate7558-80-7764091022pH Adjustment,InorganicFungicide,Herbicide,MicrobiocideSodium fluoride7681-49-475202537WoodInorganicPreservative,InsecticideSodium fluosilicate16893-85-975306538InsecticideInorganicSodium hexametaphosphate10124-56-8764021623pH AdjustmentInorganicSodium hydrosulfite7775-14-6782023408pH AdjustmentInorganicSodium hydroxide1310-73-275603362pH Adjustment,InorganicFungicide,Herbicide,MicrobiocideSodium hypobromiteNA 1442NA 214NA 213MicrobiocideInorganicSodium hypochlorite7681-52-914703539Microbiocide,InorganicWaterTreatment,NematicideSodium hypophosphate13721-43-2NA 8483409N/AInorganicSodium hypophosphite7681-53-0NA 8493410N/AInorganicSodium iodide7681-82-575702NA 695N/AInorganicSodium metabisulfite7681-57-4NA 191NA 190FungicideInorganicSodium metaborate7775-19-111104689InsecticideInorganicSodium metaborate octahydrateNA 1045NA 1544012InsecticideInorganicSodium metaborateNA 1046NA 1544013InsecticideInorganictetrahydrateSodium metasilicate6834-92-072604940Insecticide,InorganicAdjuvant,Fungicide,MicrobiocideSodium metasilicate,6834-92-0726041840Insecticide,InorganicanhydrousAdjuvant,Fungicide,MicrobiocideSodium molybdate7631-95-0NA 8551761N/AInorganicSodium nitrate7631-99-476104696Rodenticide,InorganicMicrobiocideSodium nitrite7632-00-0762042862Rodenticide,InorganicMicrobiocideSodium oxalate62-76-09604NA 111MicrobiocideInorganicSodium pentaborate11139-65-4NA 8621347Insecticide,InorganicPlant GrowthRegulatorSodium perborate2092204#####3429InsecticideInorganicSodium perborate (NaBO3)10486-00-711108NA 115InsecticideInorganictetrahydrateSodium permanganate10101-50-5NA 1453430N/AInorganicSodium peroxide (Na2(O2))1313-60-663606NA 526Microbiocide,InorganicFungicide,Herbicide,RodenticideSodium persulfate7775-27-1636032336N/AInorganicSodium phosphate7558-79-4764031790pH Adjustment,InorganicFungicide,Herbicide,MicrobiocideSodium phosphate, monobasic7558-80-7764093433pH Adjustment,InorganicFungicide,Herbicide,MicrobiocideSodium polysulfide1344-08-76902541Insecticide,InorganicFungicideSodium pyroarsenate13464-42-1134012864WoodInorganic-arsenic,Preservative,Heavy metalFungicideSodium selenate13410-01-072002NA 672N/AInorganicSodium sesquicarbonate533-96-0735071292pH Adjustment,InorganicFungicide,Microbiocide,HerbicideSodium silicate1344-09-8726032865Insecticide,InorganicAdjuvant,Fungicide,MicrobiocideSodium silicoaluminateNA 1005NA 8682866AdjuvantInorganicSodium silver thiosulfateNA 1398NA 197NA 196HerbicideInorganic-Silver,Heavy metalSodium sulfate7757-82-656041532Insecticide,InorganicHerbicideSodium sulfide1313-82-2NA 214NA 213N/AInorganicSodium sulfite7757-83-7782031635FungicideInorganicSodium tetraborate (anhydrous)1330-43-4111125054Insecticide,InorganicHerbicide,MolluscicideSodium tetraborate11130-12-4NA 8711808InsecticideInorganic(pentahydrate)Sodium tetrathiocarbonate7345-69-9#####2273Fumigant,InorganicFungicide,NematicideSodium thioarsenate17367-56-513507NA 128N/AInorganic-arsenic,(Na3AsO3S)Heavy metalSodium thiocyanate540-72-768202848HerbicideInorganicSodium thiosulfate7772-98-780104332Insecticide,InorganicFungicide,HerbicideSodium tripolyphosphate7758-29-4764041024pH AdjustmentInorganicSulfur7704-34-977501560Fungicide,InorganicInsecticideSulfur chloride10025-67-9NA 1163461N/AInorganicSulfur dichloride10545-99-0NA 9153462N/AInorganicSulfur dioxide202442277601561DessicantInorganicSulfuric acid7664-93-978001442Herbicide,InorganicDessicant,Fungicide,Microbiocide,pH AdjustmentSulfuryl chloride7791-25-578002NA 721N/AInorganicSulfuryl fluoride2699-79-878003618FumigantInorganicTalc14807-96-6NA 9232911N/AInorganicTetracopper calcium1336-15-823502NA 187FungicideInorganic-CopperoxychlorideTetrapotassium pyrophosphate7320-34-5764081918pH Adjustment,InorganicFungicide,Herbicide,MicrobiocideTetrasodium pyrophosphate7722-88-5764053474pH Adjustment,InorganicFungicide,Herbicide,MicrobiocideThallium(I) sulfate7446-18-680001NA 35RodenticideInorganic, HeavymetalTitanium dioxide13463-67-7NA 9542942N/AInorganicTitanium sulfate13825-74-6NA 1113476N/AInorganicTricopper dichloride7076-63-3#####NA 152MicrobiocideDithiocarbamate,dimethyldithiocarbamateInorganic-CopperTripotassium phosphate7778-53-2764071055pH Adjustment,InorganicFungicide,Herbicide,MicrobiocideTrisodium phosphate7601-54-9764061579pH Adjustment,InorganicFungicide,Herbicide,MicrobiocideUrea57-13-685702662Microbiocide,InorganicFungicideUrea dihydrogen sulfate21351-39-3#####2270Plant GrowthInorganicRegulator,HerbicideVermiculiteNA 778NA 1402983N/AInorganicWaterNA 557NA 1012987SolventInorganicZinc7440-66-6#####2310HerbicideInorganic-ZincZinc 2,4,5-trichlorophenate136-24-364221NA 546N/AChlorinated Phenol,Inorganic-ZincZinc 2-ethyl hexoate136-53-8412033509N/AInorganic-ZincZinc 2-pyridinethiol-1-oxide13463-41-7880022128MicrobiocideInorganic-ZincZinc 8-quinolinolate13978-85-324005NA 196Fungicide,Inorganic-zincMicrobiocideZinc abietate6798-76-1NA 1123506N/AInorganic-ZincZinc arsenate13464-44-313301NA 125Herbicide,Inorganic-Arsenic,Insecticide,Heavy metal,RodenticideInorganic-ZincZinc arsenite28837-97-013604NA 130Herbicide,Inorganic-Arsenic,Insecticide,Inorganic-Zinc,RodenticideHeavy metalZinc bacitracin1405-89-66309NA 87MicrobiocideInorganic-ZincZinc carbonate3486-35-9NA 1023507N/AInorganic-ZincZinc chloride7646-85-787801624MicrobiocideInorganic-ZincZinc dehydroabietylammonium53404-92-54211NA 75Fungicide,Inorganic-Zinc2-ethylhexanoateMicrobiocideZinc dodecyl benzene sulfonate12068-16-5NA 1123508Microbiocide,Soap, Inorganic-ZincAdjuvant,Fungicide,InsecticideZinc fluosilicate16871-71-9753071019InsecticideInorganic-ZincZinc formate557-41-587802NA 838N/AInorganic-ZincZinc hydroxide20427-58-1885013510N/AInorganic-ZincZinc isodecanoate30304-30-441222NA 355N/AInorganic-ZincZinc isononanoate5398-80-641212NA 353N/AInorganic-ZincZinc isooctanoate84082-93-941205NA 351N/AInorganic-ZincZinc mercury chromate22323-45-121004NA 170FungicideInorganic-Mercury,Inorganic-chromium(VI),Inorganic-Zinc,Heavy metalZinc naphthenate12001-85-3883011111WoodInorganic-ZincPreservative,Insecticide,Fungicide, Dogand CatRepellentZinc neodecanoate27253-29-897502NA 853N/AInorganic-ZincZinc oxide1314-13-288502666Fungicide,Inorganic-ZincAdjuvantZinc petroleum (C20-C30)68989-17-388503NA 841N/AInorganic-ZincsulfonateZinc phenol sulfonate127-82-289002NA 842N/AInorganic-ZincZinc phosphide1314-84-788601626RodenticideInorganic-ZincZinc resinate9010-69-977001NA 712N/AInorganic-ZincZinc silicateNA 13188103NA 176MicrobiocideInorganic-ZincZinc stearate557-05-1770023511N/AInorganic-ZincZinc sulfate7733-02-089001667Microbiocide,Inorganic-ZincHerbicideZinc sulfate, anhydrous7733-02-0890011852Microbiocide,Inorganic-ZincHerbicideZinc sulfate, basic68813-94-589101NA 843N/AInorganic-ZincZinc sulfate, monohydrate7446-19-7#####2995HerbicideInorganic-ZincZinc trichlorophenate30143-22-764213NA 543MicrobiocideChlorinated Phenol,Inorganic-ZincZineb12122-67-714506627FungicideDithiocarbamate,Inorganic-ZincZineb-ethylene thiuramNA 1465NA 217NA 216FungicideDithiocarbamate,disulfide adductInorganic-ZincZiram137-30-434805629Fungicide,Dithiocarbamate,Microbiocide,Inorganic-ZincDog and CatRepellentZiram, cyclohexylamine16509-79-8348061328Dog and CatDithiocarbamate,complexRepellent,Inorganic-ZincFungicide(3-Ethoxypropyl)mercury6012-84-6#####NA 147FungicideOrganomercury,bromideHeavy metal(3-Hydroxy-2-69653-69-6#####NA 153N/AOrganomercury,methoxypropyl)mercuricHeavy metalacetate10,10′-Oxybisphenoxyarsine58-36-6126011402Fungicide,Organoarsenic,MicrobiocideHeavy metal2-(acetoxymercuri)ethanol4665-55-841501NA 356N/AOrganomercury,Heavy metal3-(Hydroxymercuri)-4-nitro-o-53404-55-052604NA 447MicrobiocideOrganomercury,phenol, sodium saltHeavy metalAmmonium arsenate7784-44-3136012380Herbicide,Inorganic-arsenic,Insecticide,Heavy metalRodenticideAmmonium dichromate214970168305NA 607WoodInorganic-PreservativeChromium(VI),Heavy metalAnilinocadmium dilactate19651-91-364601NA 548N/AInorganic-Cadmium,Heavy metalArsenic7440-38-2NA 121710Herbicide,Inorganic-arsenic,Insecticide,Heavy metalRodenticideArsenic acid7778-39-4680140Herbicide,Inorganic-arsenic,Insecticide,Heavy metalRodenticideArsenic disulfide56320-22-06901NA 98Herbicide,Inorganic-arsenic,Insecticide,Heavy metalRodenticideArsenic pentoxide1303-28-26802631Fungicide,Inorganic-arsenic,Insecticide,Heavy metalRodenticide,HerbicideArsenic sulfide12612-21-46901NA 99Herbicide,Inorganic-arsenic,Insecticide,Heavy metalRodenticideArsenic trioxide1327-53-3700142Herbicide,Inorganic-arsenic,Insecticide,Heavy metalRodenticideArsenic trisulfide1303-33-96901NA 97Herbicide,Inorganic-arsenic,Insecticide,Heavy metalRodenticideArsenosobenzene637-03-67101NA 100N/AOrganoarsenic,Heavy metalArsonic acid, (4-aminophenyl)-98-50-0#####NA 109N/AOrganoarsenic,Heavy metalArsonic acid, ammonium salt58829-95-1#####NA 105Herbicide,Inorganic-arsenic,Insecticide,Heavy metalWoodPreservativeAzocyclotin41083-11-8#####2408InsecticideOrganotin, HeavymetalBasic bismuth gallate99-26-398601NA 860N/AHeavy metalBasic copper arsenate16102-92-4#####NA 132Herbicide,Inorganic-arsenic,Insecticide,Heavy metal,RodenticideInorganic-CopperBasic lead silicate53466-66-348003NA 417N/AInorganic-Lead,Heavy metalBis (tributyltin) adipate7437-35-6831171990Antifoulant,Organotin, HeavyMicrobiocidemetalBis (tributyltin) sulfide4808-30-4831131886Antifoulant,Organotin, HeavyMicrobiocidemetalBis (tributyltin) sulfoneNA 970NA 4761665Antifoulant,Organotin, HeavyMicrobiocidemetalBis(tributyltin)12379-54-383101NA 824Antifoulant,Organotin, HeavydodecenylsuccinateMicrobiocidemetalBis(tributyltin) salicylate22330-14-9831025074Antifoulant,Organotin, HeavyMicrobiocidemetalBis(tributyltin) succinate4644-96-68310374Antifoulant,Organotin, HeavyMicrobiocidemetalBis(tributyltin) sulfosalicylate4419-22-183104NA 825Antifoulant,Organotin, HeavyMicrobiocidemetalBis(tripropyltin) oxide1067-29-483201NA 829Microbiocide,Organotin, HeavyFungicidemetalCacodylic acid75-60-51250132Herbicide,Organoarsenic,DefoliantHeavy metalCadmium7440-43-9NA 4602438N/AInorganic-Cadmium,Heavy metalCadmium carbonate513-78-01290193N/AInorganic-Cadmium,Heavy metalCadmium chloride10108-64-21290294N/AInorganic-Cadmium,Heavy metalCadmium cocoate72869-63-7NA 4593085N/AInorganic-Cadmium,Heavy metalCadmium oxide1306-19-0#####NA 130N/AInorganic-Cadmium,Heavy metalCadmium perborateNA 969NA 4613086N/AInorganic-Cadmium,Heavy metalCadmium sebacate93949912903699N/AInorganic-Cadmium,Heavy metalCadmium succinate141-00-41290492N/AInorganic-Cadmium,Heavy metalCadmium sulfate10124-36-412905NA 123N/AInorganic-Cadmium,Heavy metalCadmium yellow pigmentsNA 967NA 4482439N/AInorganic-Cadmium,Heavy metalCalcium acid methanearsonate5902-95-413806101Herbicide,Organoarsenic,DefoliantHeavy metalCalcium arsenate7778-44-11350196Herbicide,Inorganic-arsenic,Insecticide,Heavy metalRodenticide,MolluscicideCalcium arsenite53404-59-413602NA 129Herbicide,Inorganic-arsenic,Insecticide,Heavy metalRodenticideCalcium methanearsonate6423-72-913809NA 136Herbicide,Organoarsenic,DefoliantHeavy metalCalcium propanearsonate126-94-313801NA 133Herbicide,Organoarsenic,DefoliantHeavy metalCalomel10112-91-152201100FungicideInorganic-Mercury,Heavy metalChloromethoxy propyl1319-86-418401887N/AOrganomercury,mercuric acetamideHeavy metalChromated zinc chlorideNA 1026878011187Insecticide,Inorganic-Herbicide,Chromium(VI),MicrobiocideInorganic-Zinc,Heavy metalChromic acetate1066-30-421102NA 172WoodInorganic-PreservativeChromium(VI),Heavy metalChromic acid7738-94-5211011188WoodInorganic-PreservativeChromium(VI),Heavy metalChromic oxide1308-38-921103NA 173WoodInorganic-PreservativeChromium(VI),Heavy metalCopper arsenate10103-61-422801NA 178Herbicide,Inorganic-arsenic,Insecticide,Heavy metal,RodenticideInorganic-CopperCopper arsenite10290-12-722401NA 177Herbicide,Inorganic-arsenic,Insecticide,Heavy metal,RodenticideInorganic-CopperCopper-zinc chromate complex1344-74-721003163Fungicide,Inorganic-WoodChromium(VI),PreservativeInorganic-Zinc,Heavy metal,Inorganic-CopperCrag turf fungicide 53112001-20-621006NA 171FungicideInorganic-Cadmium,(Cd—Cu—Ca—Zn-Chromate)Inorganic-Chromium(VI),Inorganic-Zinc,Heavy metalCupric acetoarsenite12002-03-8226012485WoodInorganic-arsenic,PreservativeHeavy metal,Inorganic-CopperCyhexatin13121-70-5#####1638InsecticideOrganotin, HeavymetalDecafentin15652-38-7#####NA 132N/AOrganotin, HeavymetalDi(phenylmercuri) ammonium18467-88-466002NA 551N/AOrganomercury,propionateHeavy metalDi(phenylmercuric) dodecenyl27236-65-366001501Microbiocide,Organomercury,succinateFungicideHeavy metalDibutyltin dichloride683-18-183123NA 828N/AOrganotin, HeavymetalDodecyl ammonium53404-47-013805857Herbicide,Organoarsenic,methanearsonateDefoliantHeavy metalDSMA144-21-813802251Herbicide,Organoarsenic,DefoliantHeavy metalEthylene oxide condensate of56573-85-4NA 1261864Antifoulant,Organotin, Heavyabietylamine, tributyltinMicrobiocidemetalchlorideEthylmercuric phosphate2235-25-841505357N/AOrganomercury,Heavy metalEthylmercurichlorendiimide2597-93-545301NA 383N/AOrganomercury,Heavy metalEthylmercurithiosalicylic acid148-61-878902NA 724FungicideOrganomercury,Heavy metalEthylmercury 2,3-2597-92-441507NA 361FungicideOrganomercury,dihydroxypropylmercaptideHeavy metalEthylmercury acetate109-62-641502NA 357FungicideOrganomercury,Heavy metalEthylmercury bromide107-26-6#####NA 149FungicideOrganomercury,Heavy metalEthylmercury chloride107-27-741503NA 358FungicideOrganomercury,Heavy metalEthylmercury22232-28-641504NA 359MicrobiocideOrganomercury,pentachlorophenateChlorinated Phenol,Heavy metalFatty acid* - silver complex24927-67-172505NA 675Microbiocide,Inorganic-Silver,*(100% C8)Fungicide,Heavy metalHerbicideFenbutatin-oxide13356-08-6#####1876InsecticideOrganotin, HeavymetalFentin hydroxide76-87-983601599Fungicide,Organotin, HeavyMolluscicide,metalHerbicideHydroxymercuri-o-nitrophenol30284-78-7526012606MicrobiocideOrganomercury,Heavy metalHydroxymercuri-o-nitrophenol,1300-34-152602NA 445MicrobiocideOrganomercury,sodium saltHeavy metalHydroxymercurichlorophenols53466-93-646002NA 391MicrobiocideOrganomercury,Heavy metalHydroxymercuriphenyl53466-95-846003NA 392MicrobiocideOrganomercury,ammonium triethanolamineHeavy metalHydroxymercury cresol12379-66-746001NA 390MicrobiocideInorganic-Mercury,Heavy metal, PhenolsLactoxymercuriphenyl53466-98-151901NA 429MicrobiocideOrganomercury,ammonium lactateHeavy metalLauric acid, barium cadmium15337-60-7NA 1183676AdjuvantInorganic-Cadmium,saltHeavy metalLead7439-92-1NA 1342638N/AInorganic-Lead,Heavy metalLead acetate301-04-248001NA 415N/AInorganic-Lead,Heavy metalLead arsenate7784-40-913503353Herbicide,Inorganic-arsenic,Insecticide,Inorganic-lead,RodenticideHeavy metalLead arsenate, basic1327-31-713502354Herbicide,Inorganic-arsenic,Insecticide,Inorganic-lead,RodenticideHeavy metalLead metasilicateNA 938NA 1381106N/AInorganic-Lead,Heavy metalLead monoxide10190-55-3NA 1231271N/AInorganic-Lead,Heavy metalLead naphthenate61790-14-5480043296N/AInorganic-Lead,Heavy metalLitharge1317-36-848002NA 416N/AInorganic-Lead,Heavy metalMagnesium arsenate10103-50-113504NA 126Herbicide,Inorganic-arsenic,Insecticide,Heavy metalRodenticideManganese arsenate7784-38-513506NA 127Herbicide,Inorganic-arsenic,Insecticide,Heavy metalRodenticideMercuric acetate1600-27-752104NA 441N/AInorganic-Mercury,Heavy metalMercuric chloride7487-94-752001372FungicideInorganic-Mercury,Heavy metalMercuric dimethyl15415-64-234808709MicrobiocideInorganic-Mercury,dithiocarbamateHeavy metal,DithiocarbamateMercuric iodide7774-29-052003NA 438N/AInorganic-Mercury,Heavy metalMercuric oleate1191-80-6521053276N/AInorganic-Mercury,Heavy metalMercuric oxide21908-53-252102955FungicideInorganic-Mercury,Heavy metalMercury7439-97-652301NA 26N/AInorganic-Mercury,Heavy metalMercury naphthenate1336-96-552101NA 439WoodInorganic-Mercury,Preservative,Heavy metalInsecticide,FungicideMercury pentanedione14024-55-652103NA 440N/AInorganic-Mercury,Heavy metalMercury phenate588-66-952106NA 442N/AInorganic-Mercury,Heavy metalMetallic silver7440-22-4725012125Microbiocide,Inorganic-Silver,Fungicide,Heavy metalHerbicideMethane arsonic acid (MAA)124-58-3#####NA 27N/AOrganoarsenic,Heavy metalMethoxyethylmercury acetate151-38-241508NA 362FungicideOrganomercury,Heavy metalMethylenebis(thiocyanate) with76397-81-481408NA 785Antifoulant,Organotin, HeavyTBTOMicrobiocidemetalMethylmercurichlorendimide5902-79-445302NA 384N/AOrganomercury,Heavy metalMethylmercury 2,3-2597-95-751905NA 433FungicideOrganomercury,dihydroxypropylmercaptideHeavy metalMethylmercury 8-86-85-151902NA 430FungicideOrganomercury,hydroxyquinolinateHeavy metalMethylmercury acetate108-07-651903NA 431FungicideOrganomercury,Heavy metalMethylmercury benzoate3626-13-951904NA 432FungicideOrganomercury,Heavy metalMethylmercury dicyano502-39-651909454FungicideOrganomercury,diamideHeavy metalMethylmercury hydroxide1184-57-251906NA 434FungicideOrganomercury,Heavy metalMethylmercury nitrile2597-97-951907NA 435FungicideOrganomercury,Heavy metalMethylmercury propionate146088351908NA 436FungicideOrganomercury,Heavy metalMonoammonium2321-53-113808NA 135Herbicide,Organoarsenic,methanearsonateDefoliantHeavy metalMonotributyltin salicylate4342-30-783122NA 827Antifoulant,Organotin, HeavyMicrobiocidemetalMSMA2163-80-61380334Herbicide,Organoarsenic,DefoliantHeavy metalN-(Ethylmercury)-p-517-16-841506NA 360FungicideOrganomercury,toluenesulfonanilideHeavy metalN-(Phenylmercuri) urea2279-64-3#####NA 160HerbicideOrganomercury,Heavy metalN-5980-82-566009NA 556FungicideOrganomercury,(Phenylmercuri)ethylenediamineHeavy metalo-(Chloromercuri)phenol90-03-9#####NA 135MicrobiocideOrganomercury,Heavy metalo-(Hydroxymercuri)benzoic5722-59-852603NA 446MicrobiocideOrganomercury,acid, cyclic anhydrideHeavy metalOctylammonium6379-37-91380427Herbicide,Organoarsenic,methanearsonateDefoliantHeavy metalp-tert-53433-01-552002NA 437MicrobiocideInorganic-Mercury,OctylphenoxyethoxyethylHeavy metaldimethyl benzyl ammoniummercuric chlorideParis green12002-03-822601460WoodInorganic-Arsenic,PreservativeInorganic-Copper,Heavy metalPhenarsazine chloride578-94-9639011342N/AOrganoarsenic,Heavy metalPhenarsazine oxide4095-45-812602NA 122N/AOrganoarsenic,Heavy metalPhenylmercuriammonium53404-68-566023NA 567FungicideOrganomercury,propionateHeavy metalPhenylmercuric 2-13302-00-666024NA 568Fungicide,Organomercury,ethylhexanoateMicrobiocideHeavy metalPhenylmercuric borate6273-99-066005NA 552Fungicide,Organomercury,MicrobiocideHeavy metalPhenylmercuric carbonate53404-69-666006NA 553Fungicide,Organomercury,MicrobiocideHeavy metalPhenylmercuric chloride100-56-166007NA 554Fungicide,Organomercury,MicrobiocideHeavy metalPhenylmercuric32407-99-166008NA 555Microbiocide,Organomercury,dimethyldithiocarbamateFungicideDithiocarbamate,Heavy metalPhenylmercuric formamide22894-47-966010NA 557Fungicide,Organomercury,Microbiocide,Heavy metalHerbicidePhenylmercuric hydroxide100-57-266011NA 558Fungicide,Organomercury,Microbiocide,Heavy metalHerbicidePhenylmercuric lactate122-64-5660121535Microbiocide,Organomercury,Fungicide,Heavy metalHerbicidePhenylmercuric5822-97-966013NA 559Fungicide,Organomercury,monoethanolammoniumMicrobiocide,Heavy metalacetateHerbicidePhenylmercuric53404-70-966014NA 560Fungicide,Organomercury,monoethanolammonium lactateMicrobiocide,Heavy metalHerbicidePhenylmercuric naphthenate31632-68-566015NA 561WoodOrganomercury,Preservative,Heavy metalInsecticide,FungicidePhenylmercuric nitrate55-68-566016477Microbiocide,Organomercury,Fungicide,Heavy metalHerbicidePhenylmercuric octanoate13864-38-566025NA 569Fungicide,Organomercury,Microbiocide,Heavy metalHerbicidePhenylmercuric oleate104-60-966022853Microbiocide,Organomercury,Fungicide,Heavy metalHerbicidePhenylmercuric propionate103-27-566018NA 563Fungicide,Organomercury,Microbiocide,Heavy metalHerbicidePhenylmercuric salicylate28086-13-766019NA 564Fungicide,Organomercury,Microbiocide,Heavy metalHerbicidePhenylmercuric thiocyanate16751-55-666020NA 565Microbiocide,Organomercury,Fungicide,Heavy metalHerbicidePhenylmercuritriethanolammonium23319-66-666021NA 566Microbiocide,Organomercury,lactateFungicide,Heavy metalHerbicidePhenylmercury 8-14354-56-466017NA 562Fungicide,Organomercury,hydroxyquinolinolateMicrobiocide,Heavy metalHerbicidePhenylmercury benzoate94-43-951900NA 428Fungicide,Organomercury,Microbiocide,Heavy metalHerbicidePMA62-38-466003491Fungicide,Organomercury,Microbiocide,Heavy metalHerbicidePMA, other relatedNA 1106NA 16490491Fungicide,Organomercury,Herbicide,Heavy metalMicrobiocidePMAA53404-67-466004492Fungicide,Organomercury,MicrobiocideHeavy metalPoly (methylmethacrylate-co-26354-18-7831195075Antifoulant,Organotin, Heavytributyltin methacrylate)MicrobiocidemetalPotassium arsenite10124-50-213605NA 131Herbicide,Inorganic-arsenic,Insecticide,Heavy metalRodenticidePotassium arsenite13464-35-213605NA 132Herbicide,Inorganic-arsenic,Insecticide,Heavy metalRodenticidePotassium chromate7789-00-668301700WoodInorganic-PreservativeChromium(VI),Heavy metalPotassium hexafluoroarsenate17029-22-0#####NA 160N/AInorganic-arsenic,Heavy metalPotassium mercuric iodide7783-33-752107NA 443N/AInorganic-Mercury,Heavy metalPyridylmercuric acetate1334-77-669501NA 661N/AOrganomercury,Heavy metalPyridylmercuric chloride1334-75-469502NA 662N/AOrganomercury,Heavy metalSilver acetate563-63-372507NA 676Microbiocide,Inorganic-Silver,Fungicide,Heavy metalHerbicideSilver carbonate534-16-772509NA 678Microbiocide,Inorganic-Silver,Fungicide,Heavy metalHerbicideSilver chloride7783-90-6725062324Microbiocide,Inorganic-Silver,Fungicide,Heavy metalHerbicideSilver copper zeolite130328-19-7#####NA 110MicrobiocideInorganic-Silver,Heavy metal,Inorganic-CopperSilver fluoride7775-41-972502NA 674Microbiocide,Inorganic-Silver,Fungicide,Heavy metalHerbicideSilver iodide, colloidal7783-96-2NA 1241556Microbiocide,Inorganic-Silver,Fungicide,Heavy metalHerbicideSilver nitrate7761-88-8725032856Microbiocide,Inorganic-Silver,Fungicide,Heavy metalHerbicide,Plant GrowthRegulatorSilver orthophosphate7784-09-072510NA 679Microbiocide,Inorganic-Silver,(Ag3PO4)Fungicide,Heavy metalHerbicideSilver oxide (Ag4O4)1301-96-8#####NA 111Microbiocide,Inorganic-Silver,Fungicide,Heavy metalHerbicideSilver oxide (Ag4O4)155645-89-9#####NA 111Microbiocide,Inorganic-Silver,Fungicide,Heavy metalHerbicideSilver sodium hydrogenNA 116672560NA 164MicrobiocideInorganic-Silver,zirconium phosphateHeavy metal(Ag0.18Na0.57H0.25Zr2(PO4)3)Silver thiocyanate1701-93-568203NA 606Microbiocide,Inorganic-Silver,Fungicide,Heavy metalHerbicideSilver thiuronium acrylate copolymer53404-00-572701NA 681Microbiocide,Inorganic-Silver,Fungicide,Heavy metalHerbicideSilver zeolite130328-18-6#####NA 125MicrobiocideInorganic-Silver,Heavy metalSilver zinc zeolite130328-20-0#####NA 111MicrobiocideInorganic-Silver,Inorganic-Zinc,Heavy metalSilver, ionic14701-21-4NA 1695150Microbiocide,Inorganic-Silver,Fungicide,Heavy metalHerbicideSodium arsenate13464-38-513505283Herbicide,Inorganic-arsenic,Insecticide,Heavy metalRodenticideSodium arsenite7784-46-513603534Herbicide,Inorganic-arsenic,Insecticide,Heavy metalRodenticide,FungicideSodium cacodylate124-65-2125021673Herbicide,Organoarsenic,Defoliant,Heavy metalRodenticideSodium chromate2144646683031241WoodInorganic-PreservativeChromium(VI),Heavy metalSodium dichromate10588-01-9683043395WoodInorganic-PreservativeChromium(VI),Heavy metalSodium54-64-878901NA 723N/AOrganomercury,ethylmercurithiosalicylateHeavy metalSodium pyroarsenate13464-42-1134012864WoodInorganic-arsenic,Preservative,Heavy metalFungicideSodium silver thiosulfateNA 1398NA 197NA 196HerbicideInorganic-Silver,Heavy metalSodium thioarsenate17367-56-513507NA 128N/AInorganic-arsenic,(Na3AsO3S)Heavy metalThallium(I) sulfate7446-18-680001NA 35RodenticideInorganic, HeavymetalTolylmercuric acetate1300-78-3#####NA 150FungicideOrganomercury,Heavy metalTri-n-butyltin maleate14275-57-1831182185Antifoulant,Organotin, HeavyMicrobiocidemetalTributyltin acetate56-36-0831052097Antifoulant,Organotin, HeavyMicrobiocidemetalTributyltin acrylate13331-52-783121NA 826Antifoulant,Organotin, HeavyMicrobiocidemetalTributyltin benzoate4342-36-3831061114Antifoulant,Organotin, HeavyMicrobiocidemetalTributyltin chloride1461-22-9831071891Antifoulant,Organotin, HeavyMicrobiocidemetalTributyltin chloride complex of56573-85-4831081412Antifoulant,Organotin, Heavyethylene oxide condensate ofMicrobiocidemetalabietylamineTributyltin chloride,NA 1012NA 970938Antifoulant,Organotin, Heavymyristylamine saltMicrobiocidemetalTributyltin fluoride29131831121030Antifoulant,Organotin, HeavyMicrobiocide,metalFungicideTributyltin isopropyl succinate53404-82-3831151115Antifoulant,Organotin, HeavyMicrobiocidemetalTributyltin linoleate24124-25-2831091116Antifoulant,Organotin, HeavyMicrobiocidemetalTributyltin methacrylate2155-70-6831202179Antifoulant,Organotin, HeavyMicrobiocidemetalTributyltin monopropylene53466-85-6831101985Antifoulant,Organotin, Heavyglycol maleateMicrobiocidemetalTributyltin neodecanoate28801-69-6831111035Antifoulant,Organotin, HeavyMicrobiocidemetalTributyltin oxide56-35-983001569Antifoulant,Organotin, HeavyMicrobiocide,metalMolluscicide,FungicideTributyltin resinate13387-91-2831141732Antifoulant,Organotin, HeavyMicrobiocidemetalTributyltin sulfide4808-30-4831131352Antifoulant,Organotin, HeavyMicrobiocidemetalTriethanolamine cacodylate69484-14-612503NA 121Herbicide,Organoarsenic,DefoliantHeavy metalTriethanolamine5902-97-613807NA 134Herbicide,Organoarsenic,methanearsonateDefoliantHeavy metalTrimethyltin chloride1066-45-1#####NA 161N/AOrganotin, HeavymetalTriphenylbismuthine603-33-882801NA 821N/AHeavy metalTriphenylbismuthine dichloride594-30-982802NA 822N/AHeavy metalTriphenyltin acetate900-95-8#####NA 153Fungicide,Organotin, HeavyHerbicidemetalTriphenyltin chloride639-58-7#####NA 153N/AOrganotin, HeavymetalTriphenyltin fluoride379-52-2836022212AntifoulantOrganotin, HeavymetalTripropyltin methacrylate4154-35-283202NA 830N/AOrganotin, HeavymetalZinc arsenate13464-44-313301NA 125Herbicide,Inorganic-Arsenic,Insecticide,Heavy metal,RodenticideInorganic-ZincZinc arsenite28837-97-013604NA 130Herbicide,Inorganic-Arsenic,Insecticide,Inorganic-Zinc,RodenticideHeavy metalZinc mercury chromate22323-45-121004NA 170FungicideInorganic-Mercury,Inorganic-chromium(VI),Inorganic-Zinc,Heavy metalAmmonium arsenate7784-44-3136012380Herbicide,Inorganic-arsenic,Insecticide,Heavy metalRodenticideArsenic7440-38-2NA 121710Herbicide,Inorganic-arsenic,Insecticide,Heavy metalRodenticideArsenic acid7778-39-4680140Herbicide,Inorganic-arsenic,Insecticide,Heavy metalRodenticideArsenic disulfide56320-22-06901NA 98Herbicide,Inorganic-arsenic,Insecticide,Heavy metalRodenticideArsenic pentoxide1303-28-26802631Fungicide,Inorganic-arsenic,Insecticide,Heavy metalRodenticide,HerbicideArsenic sulfide12612-21-46901NA 99Herbicide,Inorganic-arsenic,Insecticide,Heavy metalRodenticideArsenic trioxide1327-53-3700142Herbicide,Inorganic-arsenic,Insecticide,Heavy metalRodenticideArsenic trisulfide1303-33-96901NA 97Herbicide,Inorganic-arsenic,Insecticide,Heavy metalRodenticideArsonic acid, ammonium salt58829-95-1#####NA 105Herbicide,Inorganic-arsenic,Insecticide,Heavy metalWoodPreservativeBasic copper arsenate16102-92-4#####NA 132Herbicide,Inorganic-arsenic,Insecticide,Heavy metal,RodenticideInorganic-CopperCalcium arsenate7778-44-11350196Herbicide,Inorganic-arsenic,Insecticide,Heavy metalRodenticide,MolluscicideCalcium arsenite53404-59-413602NA 129Herbicide,Inorganic-arsenic,Insecticide,Heavy metalRodenticideCopper arsenate10103-61-422801NA 178Herbicide,Inorganic-arsenic,Insecticide,Heavy metal,RodenticideInorganic-CopperCopper arsenite10290-12-722401NA 177Herbicide,Inorganic-arsenic,Insecticide,Heavy metal,RodenticideInorganic-CopperCupric acetoarsenite12002-03-8226012485WoodInorganic-arsenic,PreservativeHeavy metal,Inorganic-CopperLead arsenate7784-40-913503353Herbicide,Inorganic-arsenic,Insecticide,Inorganic-lead,RodenticideHeavy metalLead arsenate, basic1327-31-713502354Herbicide,Inorganic-arsenic,Insecticide,Inorganic-lead,RodenticideHeavy metalMagnesium arsenate10103-50-113504NA 126Herbicide,Inorganic-arsenic,Insecticide,Heavy metalRodenticideManganese arsenate7784-38-513506NA 127Herbicide,Inorganic-arsenic,Insecticide,Heavy metalRodenticideParis green12002-03-822601460WoodInorganic-Arsenic,PreservativeInorganic-Copper,Heavy metalPotassium arsenite10124-50-213605NA 131Herbicide,Inorganic-arsenic,Insecticide,Heavy metalRodenticidePotassium arsenite13464-35-213605NA 132Herbicide,Inorganic-arsenic,Insecticide,Heavy metalRodenticidePotassium hexafluoroarsenate17029-22-0#####NA 160N/AInorganic-arsenic,Heavy metalSodium arsenate13464-38-513505283Herbicide,Inorganic-arsenic,Insecticide,Heavy metalRodenticideSodium arsenite7784-46-513603534Herbicide,Inorganic-arsenic,Insecticide,Heavy metalRodenticide,FungicideSodium pyroarsenate13464-42-1134012864WoodInorganic-arsenic,Preservative,Heavy metalFungicideSodium thioarsenate17367-56-513507NA 128N/AInorganic-arsenic,(Na3AsO3S)Heavy metalZinc arsenate13464-44-313301NA 125Herbicide,Inorganic-Arsenic,Insecticide,Heavy metal,RodenticideInorganic-ZincZinc arsenite28837-97-013604NA 130Herbicide,Inorganic-Arsenic,Insecticide,Inorganic-Zinc,RodenticideHeavy metalAntimony7440-36-0NA 5162388N/AAntimonyAntimony potassium tartrate28300-74-562013057InsecticideAntimonyDiphenylstibene 2-5035-58-56202NA 82MicrobiocideAntimonyethylhexanoate10,10′-Oxybisphenoxyarsine58-36-6126011402Fungicide,Organoarsenic,MicrobiocideHeavy metalArsenosobenzene637-03-67101NA 100N/AOrganoarsenic,Heavy metalArsonic acid, (4-aminophenyl)-98-50-0#####NA 109N/AOrganoarsenic,Heavy metalCacodylic acid75-60-51250132Herbicide,Organoarsenic,DefoliantHeavy metalCalcium acid methanearsonate5902-95-413806101Herbicide,Organoarsenic,DefoliantHeavy metalCalcium methanearsonate6423-72-913809NA 136Herbicide,Organoarsenic,DefoliantHeavy metalCalcium propanearsonate126-94-313801NA 133Herbicide,Organoarsenic,DefoliantHeavy metalDodecyl ammonium53404-47-013805857Herbicide,Organoarsenic,methanearsonateDefoliantHeavy metalDSMA144-21-813802251Herbicide,Organoarsenic,DefoliantHeavy metalMethane arsonic acid (MAA)124-58-3#####NA 27N/AOrganoarsenic,Heavy metalMonoammonium2321-53-113808NA 135Herbicide,Organoarsenic,methanearsonateDefoliantHeavy metalMSMA2163-80-61380334Herbicide,Organoarsenic,DefoliantHeavy metalOctylammonium6379-37-91380427Herbicide,Organoarsenic,methanearsonateDefoliantHeavy metalPhenarsazine chloride578-94-9639011342N/AOrganoarsenic,Heavy metalPhenarsazine oxide4095-45-812602NA 122N/AOrganoarsenic,Heavy metalSodium cacodylate124-65-2125021673Herbicide,Organoarsenic,Defoliant,Heavy metalRodenticideTriethanolamine cacodylate69484-14-612503NA 121Herbicide,Organoarsenic,DefoliantHeavy metalTriethanolamine5902-97-613807NA 134Herbicide,Organoarsenic,methanearsonateDefoliantHeavy metalCalomel10112-91-152201100FungicideInorganic-Mercury,Heavy metalHydroxymercury cresol12379-66-746001NA 390MicrobiocideInorganic-Mercury,Heavy metal, PhenolsMercuric acetate1600-27-752104NA 441N/AInorganic-Mercury,Heavy metalMercuric chloride7487-94-752001372FungicideInorganic-Mercury,Heavy metalMercuric dimethyl15415-64-234808709MicrobiocideInorganic-Mercury,dithiocarbamateHeavy metal,DithiocarbamateMercuric iodide7774-29-052003NA 438N/AInorganic-Mercury,Heavy metalMercuric oleate1191-80-6521053276N/AInorganic-Mercury,Heavy metalMercuric oxide21908-53-252102955FungicideInorganic-Mercury,Heavy metalMercury7439-97-652301NA 26N/AInorganic-Mercury,Heavy metalMercury naphthenate1336-96-552101NA 439WoodInorganic-Mercury,Preservative,Heavy metalInsecticide,FungicideMercury pentanedione14024-55-652103NA 440N/AInorganic-Mercury,Heavy metalMercury phenate588-66-952106NA 442N/AInorganic-Mercury,Heavy metalp-tert-53433-01-552002NA 437MicrobiocideInorganic-Mercury,OctylphenoxyethoxyethylHeavy metaldimethyl benzyl ammoniummercuric chloridePotassium mercuric iodide7783-33-752107NA 443N/AInorganic-Mercury,Heavy metalZinc mercury chromate22323-45-121004NA 170FungicideInorganic-Mercury,Inorganic-chromium(VI),Inorganic-Zinc,Heavy metal(3-Ethoxypropyl)mercury6012-84-6#####NA 147FungicideOrganomercury,bromideHeavy metal(3-Hydroxy-2-69653-69-6#####NA 153N/AOrganomercury,methoxypropyl)mercuricHeavy metalacetate2-(acetoxymercuri)ethanol4665-55-841501NA 356N/AOrganomercury,Heavy metal3-(Hydroxymercuri)-4-nitro-o-53404-55-052604NA 447MicrobiocideOrganomercury,phenol, sodium saltHeavy metalChloromethoxy propyl1319-86-418401887N/AOrganomercury,mercuric acetamideHeavy metalDi(phenylmercuri) ammonium18467-88-466002NA 551N/AOrganomercury,propionateHeavy metalDi(phenylmercuric) dodecenyl27236-65-366001501Microbiocide,Organomercury,succinateFungicideHeavy metalEthylmercuric phosphate2235-25-841505357N/AOrganomercury,Heavy metalEthylmercurichlorendiimide2597-93-545301NA 383N/AOrganomercury,Heavy metalEthylmercurithiosalicylic acid148-61-878902NA 724FungicideOrganomercury,Heavy metalEthylmercury 2,3-2597-92-441507NA 361FungicideOrganomercury,dihydroxypropylmercaptideHeavy metalEthylmercury acetate109-62-641502NA 357FungicideOrganomercury,Heavy metalEthylmercury bromide107-26-6#####NA 149FungicideOrganomercury,Heavy metalEthylmercury chloride107-27-741503NA 358FungicideOrganomercury,Heavy metalEthylmercury22232-28-641504NA 359MicrobiocideOrganomercury,pentachlorophenateChlorinated Phenol,Heavy metalHydroxymercuri-o-nitrophenol30284-78-7526012606MicrobiocideOrganomercury,Heavy metalHydroxymercuri-o-nitrophenol,1300-34-152602NA 445MicrobiocideOrganomercury,sodium saltHeavy metalHydroxymercurichlorophenols53466-93-646002NA 391MicrobiocideOrganomercury,Heavy metalHydroxymercuriphenyl53466-95-846003NA 392MicrobiocideOrganomercury,ammonium triethanolamineHeavy metalLactoxymercuriphenyl53466-98-151901NA 429MicrobiocideOrganomercury,ammonium lactateHeavy metalMethoxyethyl mercury chloride123-88-6NA 212NA 211FungicideOrganomercuryMethoxyethyl mercury silicate64491-92-5NA 208NA 208FungicideOrganomercuryMethoxyethylmercury acetate151-38-241508NA 362FungicideOrganomercury,Heavy metalMethylmercurichlorendimide5902-79-445302NA 384N/AOrganomercury,Heavy metalMethylmercury 2,3-2597-95-751905NA 433FungicideOrganomercury,dihydroxypropylmercaptideHeavy metalMethylmercury 8-86-85-151902NA 430FungicideOrganomercury,hydroxyquinolinateHeavy metalMethylmercury acetate108-07-651903NA 431FungicideOrganomercury,Heavy metalMethylmercury benzoate3626-13-951904NA 432FungicideOrganomercury,Heavy metalMethylmercury dicyano502-39-651909454FungicideOrganomercury,diamideHeavy metalMethylmercury hydroxide1184-57-251906NA 434FungicideOrganomercury,Heavy metalMethylmercury nitrile2597-97-951907NA 435FungicideOrganomercury,Heavy metalMethylmercury propionate146088351908NA 436FungicideOrganomercury,Heavy metalN-(Ethylmercury)-p-517-16-841506NA 360FungicideOrganomercury,toluenesulfonanilideHeavy metalN-(Phenylmercuri) urea2279-64-3#####NA 160HerbicideOrganomercury,Heavy metalN-5980-82-566009NA 556FungicideOrganomercury,(Phenylmercuri)ethylenediamineHeavy metalo-(Chloromercuri)phenol90-03-9#####NA 135MicrobiocideOrganomercury,Heavy metalo-(Hydroxymercuri)benzoic5722-59-852603NA 446MicrobiocideOrganomercury,acid, cyclic anhydrideHeavy metalPhenylmercuriammonium53404-68-566023NA 567FungicideOrganomercury,propionateHeavy metalPhenylmercuric 2-13302-00-666024NA 568Fungicide,Organomercury,ethylhexanoateMicrobiocideHeavy metalPhenylmercuric borate6273-99-066005NA 552Fungicide,Organomercury,MicrobiocideHeavy metalPhenylmercuric carbonate53404-69-666006NA 553Fungicide,Organomercury,MicrobiocideHeavy metalPhenylmercuric chloride100-56-166007NA 554Fungicide,Organomercury,MicrobiocideHeavy metalPhenylmercuric32407-99-166008NA 555Microbiocide,Organomercury,dimethyldithiocarbamateFungicideDithiocarbamate,Heavy metalPhenylmercuric formamide22894-47-966010NA 557Fungicide,Organomercury,Microbiocide,Heavy metalHerbicidePhenylmercuric hydroxide100-57-266011NA 558Fungicide,Organomercury,Microbiocide,Heavy metalHerbicidePhenylmercuric lactate122-64-5660121535Microbiocide,Organomercury,Fungicide,Heavy metalHerbicidePhenylmercuric5822-97-966013NA 559Fungicide,Organomercury,monoethanolammoniumMicrobiocide,Heavy metalacetateHerbicidePhenylmercuric53404-70-966014NA 560Fungicide,Organomercury,monoethanolammonium lactateMicrobiocide,Heavy metalHerbicidePhenylmercuric naphthenate31632-68-566015NA 561WoodOrganomercury,Preservative,Heavy metalInsecticide,FungicidePhenylmercuric nitrate55-68-566016477Microbiocide,Organomercury,Fungicide,Heavy metalHerbicidePhenylmercuric octanoate13864-38-566025NA 569Fungicide,Organomercury,Microbiocide,Heavy metalHerbicidePhenylmercuric oleate104-60-966022853Microbiocide,Organomercury,Fungicide,Heavy metalHerbicidePhenylmercuric propionate103-27-566018NA 563Fungicide,Organomercury,Microbiocide,Heavy metalHerbicidePhenylmercuric salicylate28086-13-766019NA 564Fungicide,Organomercury,Microbiocide,Heavy metalHerbicidePhenylmercuric thiocyanate16751-55-666020NA 565Microbiocide,Organomercury,Fungicide,Heavy metalHerbicidePhenylmercuritriethanolammonium23319-66-666021NA 566Microbiocide,Organomercury,lactateFungicide,Heavy metalHerbicidePhenylmercury 8-14354-56-466017NA 562Fungicide,Organomercury,hydroxyquinolinolateMicrobiocide,Heavy metalHerbicidePhenylmercury benzoate94-43-951900NA 428Fungicide,Organomercury,Microbiocide,Heavy metalHerbicidePhenylmercury nitrate2227736NA 209NA 208FungicideOrganomercuryPMA62-38-466003491Fungicide,Organomercury,Microbiocide,Heavy metalHerbicidePMA, other relatedNA 1106NA 16490491Fungicide,Organomercury,Herbicide,Heavy metalMicrobiocidePMAA53404-67-466004492Fungicide,Organomercury,MicrobiocideHeavy metalPyridylmercuric acetate1334-77-669501NA 661N/AOrganomercury,Heavy metalPyridylmercuric chloride1334-75-469502NA 662N/AOrganomercury,Heavy metalSodium54-64-878901NA 723N/AOrganomercury,ethylmercurithiosalicylateHeavy metalTolylmercuric acetate1300-78-3#####NA 150FungicideOrganomercury,Heavy metalAnilinocadmium dilactate19651-91-364601NA 548N/AInorganic-Cadmium,Heavy metalCadmium7440-43-9NA 4602438N/AInorganic-Cadmium,Heavy metalCadmium carbonate513-78-01290193N/AInorganic-Cadmium,Heavy metalCadmium chloride10108-64-21290294N/AInorganic-Cadmium,Heavy metalCadmium cocoate72869-63-7NA 4593085N/AInorganic-Cadmium,Heavy metalCadmium oxide1306-19-0#####NA 130N/AInorganic-Cadmium,Heavy metalCadmium perborateNA 969NA 4613086N/AInorganic-Cadmium,Heavy metalCadmium sebacate93949912903699N/AInorganic-Cadmium,Heavy metalCadmium succinate141-00-41290492N/AInorganic-Cadmium,Heavy metalCadmium sulfate10124-36-412905NA 123N/AInorganic-Cadmium,Heavy metalCadmium yellow pigmentsNA 967NA 4482439N/AInorganic-Cadmium,Heavy metalCrag turf fungicide 53112001-20-621006NA 171FungicideInorganic-Cadmium,(Cd—Cu—Ca—Zn-Chromate)Inorganic-Chromium(VI),Inorganic-Zinc,Heavy metalLauric acid, barium cadmium15337-60-7NA 1183676AdjuvantInorganic-Cadmium,saltHeavy metalAmmonium dichromate214970168305NA 607WoodInorganic-PreservativeChromium(VI),Heavy metalChromated zinc chlorideNA 1026878011187Insecticide,Inorganic-Herbicide,Chromium(VI),MicrobiocideInorganic-Zinc,Heavy metalChromic acetate1066-30-421102NA 172WoodInorganic-PreservativeChromium(VI),Heavy metalChromic acid7738-94-5211011188WoodInorganic-PreservativeChromium(VI),Heavy metalChromic oxide1308-38-921103NA 173WoodInorganic-PreservativeChromium(VI),Heavy metalCopper-zinc chromate complex1344-74-721003163Fungicide,Inorganic-WoodChromium(VI),PreservativeInorganic-Zinc,Heavy metal,Inorganic-CopperCrag turf fungicide 53112001-20-621006NA 171FungicideInorganic-Cadmium,(Cd—Cu—Ca—Zn-Chromate)Inorganic-Chromium(VI),Inorganic-Zinc,Heavy metalPotassium chromate7789-00-668301700WoodInorganic-PreservativeChromium(VI),Heavy metalPotassium dichromate7778-50-9683022167WoodInorganic-PreservativeChromium(VI)Sodium bichromate dihydrate7789-12-0683063980WoodInorganic-PreservativeChromium(VI),InorganicSodium chromate2144646683031241WoodInorganic-PreservativeChromium(VI),Heavy metalSodium dichromate10588-01-9683043395WoodInorganic-PreservativeChromium(VI),Heavy metalZinc mercury chromate22323-45-121004NA 170FungicideInorganic-Mercury,Inorganic-chromium(VI),Inorganic-Zinc,Heavy metalAcetic acid, copper (2+) salt142-71-2NA 6973013N/AInorganic-CopperBasic copper arsenate16102-92-4#####NA 132Herbicide,Inorganic-arsenic,Insecticide,Heavy metal,RodenticideInorganic-CopperBordeaux mixtureNA 240NA 47880FungicideInorganic-CopperChlorophyllin11006-34-1NA 191NA 190Fungicide,Inorganic-Copper,MicrobiocideBotanicalCopper7440-50-822501714FungicideInorganic-CopperCopper (from triethanolamine82027-59-624403NA 198AlgaecideInorganic-Coppercomplex)Copper 2-ethylhexanoate22221-10-9412012235FungicideInorganic-CopperCopper 3-phenylsalicylate125068223801NA 191N/AInorganic-CopperCopper 8-quinolinoleate10380-28-624002159Fungicide,Inorganic-CopperMicrobiocideCopper abietate10248-55-223301NA 184FungicideInorganic-CopperCopper acetate83163244002147FungicideInorganic-CopperCopper ammonium acetateNA 1544NA 225NA 225FungicideInorganic-CopperCopper ammonium carbonate33113-08-5227031762FungicideInorganic-CopperCopper ammonium complex16828-95-8227023550FungicideInorganic-CopperCopper arsenate10103-61-422801NA 178Herbicide,Inorganic-arsenic,Insecticide,Heavy metal,RodenticideInorganic-CopperCopper arsenite10290-12-722401NA 177Herbicide,Inorganic-arsenic,Insecticide,Heavy metal,RodenticideInorganic-CopperCopper as elemental from50376-91-524404NA 199N/AInorganic-Coppercopper - etidronic acid complexCopper beta cyclodextrinNA 1366NA 193NA 193FungicideInorganic-CopperhydroxideCopper bronze powder7440-50-8225011457AntifoulantInorganic-CopperCopper carbonate, basic1184-64-12290160Fungicide,Inorganic-CopperAlgaecide,InsecticideCopper chloride (anhydrous)1344-67-823802NA 192N/AInorganic-CopperCopper chloride (dihydrate)10125-13-023701NA 190N/AInorganic-CopperCopper citrate10402-15-0440051406N/AInorganic-CopperCopper citrate chelateNA 961NA 3873547N/AInorganic-CopperCopper complex with ammonia67989-88-2#####NA 130FungicideInorganic-Copperand ethylene diaminetetraacetateCopper cresylate12379-42-923001NA 181FungicideInorganic-CopperCopper53404-24-341202NA 349N/AInorganic-Copperdehydroabietylammonium 2-ethylhexanoateCopper dihydrazinium sulfate33271-65-750504753N/AInorganic-CopperCopper ethanolamine complex14215-52-224409NA 201AlgaecideInorganic-CopperCopper ethanolamineNA 1044NA 1463551AlgaecideInorganic-Coppercomplexes, mixedCopper ethylenediamine13426-91-0244073549HerbicideInorganic-CoppercomplexCopper gluconate chelate814-91-5233053548N/AInorganic-CopperCopper hydrazinium sulfate53433-02-650501NA 418FungicideInorganic-CopperCopper hydroxide20427-59-223401151Fungicide,Inorganic-CopperMicrobiocide,NematicideCopper hydroxide - NA 1017NA 1051826N/AInorganic-Coppertriethanolamine complexCopper isodecanoate84082-88-241221NA 354N/AInorganic-CopperCopper isononanoate72915-82-341211NA 352N/AInorganic-CopperCopper isooctanoate88859-94-341204NA 350N/AInorganic-CopperCopper lactate16039-52-423302NA 185N/AInorganic-CopperCopper linoleate7721-15-5233031110N/AInorganic-CopperCopper metaborate39290-85-222802NA 179N/AInorganic-CopperCopper monoethanolamineNA 960NA 3843552N/AInorganic-CoppercomplexCopper naphthenate1338-02-923102153WoodInorganic-CopperPreservative,Insecticide,Fungicide, Dogand CatRepellentCopper naphthenate1338-02-96000NA 172WoodInorganic-CopperPreservative,Insecticide,Fungicide, Dogand CatRepellentCopper naphthenate1338-02-96300NA 172WoodInorganic-CopperPreservative,Insecticide,Fungicide, Dogand CatRepellentCopper nitroacetate22221-12-123201NA 183N/AInorganic-CopperCopper octanoate20543-04-8233065225FungicideInorganic-CopperCopper oleate10402-16-123304154FungicideInorganic-CopperCopper oxide (ic)1317-38-0424012231Fungicide,Inorganic-CopperInsecticideCopper oxide (ous)1317-39-125601175Fungicide,Inorganic-CopperInsecticideCopper oxychloride1332-40-78001156FungicideInorganic-CopperCopper oxychloride1332-65-623501NA 186FungicideInorganic-Copper(Cu2Cl(OH)3)Copper oxychloride sulfate8012-69-923503158FungicideInorganic-CopperCopper oxysulfate12158-97-323504NA 188N/AInorganic-CopperCopper oxysulfate82010-79-523504NA 189N/AInorganic-CopperCopper pentachlorophenate15773-35-063011NA 512WoodChlorinated Phenol,Preservative,Inorganic-CopperMicrobiocide,Algaecide,FungicideCopper phosphate10103-48-722902NA 180N/AInorganic-CopperCopper phthalocyanine147-14-8NA 3812479DyeInorganic-CopperCopper pyrophosphate10102-90-669701NA 663N/AInorganic-CopperCopper salts of fatty and rosin9007-39-023104155FungicideInorganic-CopperacidsCopper salts of the acids of tall61789-22-823103NA 182N/AInorganic-CopperoilCopper silicate1344-72-524301NA 197N/AInorganic-CopperCopper sodium sulfate-NA 1023NA 121755N/AInorganic-Copperphosphate complexCopper sulfate (anhydrous)7758-98-7244081778Fungicide,Inorganic-CopperAlgaecide,MolluscicideCopper sulfate (basic)1344-73-68101162Fungicide,Inorganic-CopperAlgaecide,MolluscicideCopper sulfate (pentahydrate)7758-99-824401161Algaecide,Inorganic-CopperFungicide,Insecticide,WaterTreatment,Molluscicide,NematicideCopper sulfate ethyleneNA 1036NA 1322480N/AInorganic-CopperdiamineCopper sulfate, monohydrate10257-54-2244021789Fungicide,Inorganic-CopperAlgaecide,MolluscicideCopper sulfate, tri-basicNA 1384NA 195NA 194Herbicide,Inorganic-CopperAlgaecide,Fungicide,WaterTreatmentCopper triethanolamine68027-59-6NA 1251615AlgaecideInorganic-CoppercomplexCopper-zinc chromate complex1344-74-721003163Fungicide,Inorganic-WoodChromium(VI),PreservativeInorganic-Zinc,Heavy metal,Inorganic-CopperCopper-zinc sulfate complex55072-57-68102164FungicideInorganic-Zinc,Inorganic-CopperCopper-zinc sulfate complex,NA 959NA 3821751FungicideInorganic-Zinc,monohydrateInorganic-CopperCuprammoniumNA 1382NA 195NA 194FungicideInorganic-CopperCupric acetoarsenite12002-03-8226012485WoodInorganic-arsenic,PreservativeHeavy metal,Inorganic-CopperCupric ferric subsulfate12168-20-642402NA 365MolluscicideInorganic-CoppercomplexCupric fluosilicate12062-24-775309NA 692InsecticideInorganic-CopperCupric gluconate527-09-3244053117FungicideInorganic-CopperCupric nitrate3251-23-8761023118N/AInorganic-CopperCuprous and cupric oxide,82010-82-042403NA 366N/AInorganic-CoppermixedCuprous chloride (Cu2Cl2)7758-89-6#####5597FungicideInorganic-CopperCuprous iodide7681-65-4#####NA 902N/AInorganic-CopperCuprous sulfide22205-45-4#####NA 124N/AInorganic-CopperCuprous thiocyanate1111-67-7256022108MicrobiocideInorganic-CopperDevice (swimming poolNA 1504NA 222NA 222AlgaecideInorganic-Copperalgaecide, copper generating)no guarantee requiredDihydrogen54453-03-124406NA 200N/AInorganic-Copper{ethylenediaminetetraacetato(4-)}cuprate(2-)Disodium EDTA-copper14025-15-1NA 2963173N/AInorganic-CopperEDTA diammonium copper7379-26-2391171613AlgaecideInorganic-CoppersaltEDTA, copper complex12276-01-6391051135AlgaecideInorganic-CopperLignin sulfonic acid, copperNA 933NA 1261925N/AInorganic-CoppersaltMalachite (copper equivalent1319-53-5#####NA 155N/AInorganic-Copper57%)Mixed copper chelates orNA 1437NA 213NA 212FungicideInorganic-Coppercomplex blend of copper saltsN-(2-hydroxyethyl) ethyleneNA 1025NA 1221130N/AInorganic-Copperdiamine triacetic acid, coppersaltNeodecanoic acid, copper salt50315-14-597503NA 854N/AInorganic-CopperParis green12002-03-822601460WoodInorganic-Arsenic,PreservativeInorganic-Copper,Heavy metalSilver copper zeolite130328-19-7#####NA 110MicrobiocideInorganic-Silver,Heavy metal,Inorganic-CopperTetracopper calcium1336-15-823502NA 187FungicideInorganic-CopperoxychlorideTricopper dichloride7076-63-3#####NA 152MicrobiocideDithiocarbamate,dimethyldithiocarbamateInorganic-CopperAzocyclotin41083-11-8#####2408InsecticideOrganotin, HeavymetalBis (tributyltin) adipate7437-35-6831171990Antifoulant,Organotin, HeavyMicrobiocidemetalBis (tributyltin) sulfide4808-30-4831131886Antifoulant,Organotin, HeavyMicrobiocidemetalBis (tributyltin) sulfoneNA 970NA 4761665Antifoulant,Organotin, HeavyMicrobiocidemetalBis(tributyltin)12379-54-383101NA 824Antifoulant,Organotin, HeavydodecenylsuccinateMicrobiocidemetalBis(tributyltin) salicylate22330-14-9831025074Antifoulant,Organotin, HeavyMicrobiocidemetalBis(tributyltin) succinate4644-96-68310374Antifoulant,Organotin, HeavyMicrobiocidemetalBis(tributyltin) sulfosalicylate4419-22-183104NA 825Antifoulant,Organotin, HeavyMicrobiocidemetalBis(tripropyltin) oxide1067-29-483201NA 829Microbiocide,Organotin, HeavyFungicidemetalCyhexatin13121-70-5#####1638InsecticideOrganotin, HeavymetalDecafentin15652-38-7#####NA 132N/AOrganotin, HeavymetalDibutyltin dichloride683-18-183123NA 828N/AOrganotin, HeavymetalEthylene oxide condensate of56573-85-4NA 1261864Antifoulant,Organotin, Heavyabietylamine, tributyltinMicrobiocidemetalchlorideFenbutatin-oxide13356-08-6#####1876InsecticideOrganotin, HeavymetalFentin hydroxide76-87-983601599Fungicide,Organotin, HeavyMolluscicide,metalHerbicideMethylenebis(thiocyanate) with76397-81-481408NA 785Antifoulant,Organotin, HeavyTBTOMicrobiocidemetalMonotributylin salicylate4342-30-783122NA 827Antifoulant,Organotin, HeavyMicrobiocidemetalPoly (methylmethacrylate-co-26354-18-7831195075Antifoulant,Organotin, Heavytributyltin methacrylate)MicrobiocidemetalTin Acrylate Polymers RC 626NA 1444NA 214NA 213AntifoulantOrganotin& RC 627Tri-n-butyltin maleate14275-57-1831182185Antifoulant,Organotin, HeavyMicrobiocidemetalTributyltin acetate56-36-0831052097Antifoulant,Organotin, HeavyMicrobiocidemetalTributyltin acrylate13331-52-783121NA 826Antifoulant,Organotin, HeavyMicrobiocidemetalTributyltin benzoate4342-36-3831061114Antifoulant,Organotin, HeavyMicrobiocidemetalTributyltin chloride1461-22-9831071891Antifoulant,Organotin, HeavyMicrobiocidemetalTributyltin chloride complex of56573-85-4831081412Antifoulant,Organotin, Heavyethylene oxide condensate ofMicrobiocidemetalabietylamineTributyltin chloride,NA 1012NA 970938Antifoulant,Organotin, Heavymyristylamine saltMicrobiocidemetalTributyltin fluoride29131831121030Antifoulant,Organotin, HeavyMicrobiocide,metalFungicideTributyltin isopropyl succinate53404-82-3831151115Antifoulant,Organotin, HeavyMicrobiocidemetalTributyltin linoleate24124-25-2831091116Antifoulant,Organotin, HeavyMicrobiocidemetalTributyltin methacrylate2155-70-6831202179Antifoulant,Organotin, HeavyMicrobiocidemetalTributyltin monopropylene53466-85-6831101985Antifoulant,Organotin, Heavyglycol maleateMicrobiocidemetalTributyltin naphthenate85409-17-2NA 211NA 210FungicideOrganotinTributyltin neodecanoate28801-69-6831111035Antifoulant,Organotin, HeavyMicrobiocidemetalTributyltin oxide56-35-983001569Antifoulant,Organotin, HeavyMicrobiocide,metalMolluscicide,FungicideTributyltin resinate13387-91-2831141732Antifoulant,Organotin, HeavyMicrobiocidemetalTributyltin sulfide4808-30-4831131352Antifoulant,Organotin, HeavyMicrobiocidemetalTrimethyltin chloride1066-45-1#####NA 161N/AOrganotin, HeavymetalTriphenyltin acetate900-95-8#####NA 153Fungicide,Organotin, HeavyHerbicidemetalTriphenyltin chloride639-58-7#####NA 153N/AOrganotin, HeavymetalTriphenyltin fluoride379-52-2836022212AntifoulantOrganotin, HeavymetalTripropyltin methacrylate4154-35-283202NA 830N/AOrganotin, HeavymetalBasic lead silicate53466-66-348003NA 417N/AInorganic-Lead,Heavy metalLead7439-92-1NA 1342638N/AInorganic-Lead,Heavy metalLead acetate301-04-248001NA 415N/AInorganic-Lead,Heavy metalLead arsenate7784-40-913503353Herbicide,Inorganic-arsenic,Insecticide,Inorganic-lead,RodenticideHeavy metalLead arsenate, basic1327-31-713502354Herbicide,Inorganic-arsenic,Insecticide,Inorganic-lead,RodenticideHeavy metalLead metasilicateNA 938NA 1381106N/AInorganic-Lead,Heavy metalLead monoxide10190-55-3NA 1231271N/AInorganic-Lead,Heavy metalLead naphthenate61790-14-5480043296N/AInorganic-Lead,Heavy metalLitharge1317-36-848002NA 416N/AInorganic-Lead,Heavy metalAlkyl*-1-(2-aminoethyl)-2-NA 118846606NA 167MicrobiocideInorganic-Nickel,imidazoline acetate-nickelImidazolinesulfate complexManeb and nickel sulfate8005-46-7#####NA 158FungicideDithiocarbamate,hexahydrate (014505 + 050505)Inorganic-NickelNickel7440-02-0NA 121762N/AInorganic-NickelNickel diethyl hexyl acidNA 928NA 533696N/AInorganic-Nickelphosphate complexNickel sulfate (anhydrous)7786-81-450508NA 420FungicideInorganic-NickelNickel sulfate hexahydrate10101-97-050505NA 419FungicideInorganic-NickelFatty acid*-silver complex24927-67-172505NA 675Microbiocide,Inorganic-Silver,*(100% C8)Fungicide,Heavy metalHerbicideMetallic silver7440-22-4725012125Microbiocide,Inorganic-Silver,Fungicide,Heavy metalHerbicideSilver acetate563-63-372507NA 676Microbiocide,Inorganic-Silver,Fungicide,Heavy metalHerbicideSilver carbonate534-16-772509NA 678Microbiocide,Inorganic-Silver,Fungicide,Heavy metalHerbicideSilver chloride7783-90-6725062324Microbiocide,Inorganic-Silver,Fungicide,Heavy metalHerbicideSilver copper zeolite130328-19-7#####NA 110MicrobiocideInorganic-Silver,Heavy metal,Inorganic-CopperSilver fluoride7775-41-972502NA 674Microbiocide,Inorganic-Silver,Fungicide,Heavy metalHerbicideSilver iodide, colloidal7783-96-2NA 1241556Microbiocide,Inorganic-Silver,Fungicide,Heavy metalHerbicideSilver nitrate7761-88-8725032856Microbiocide,Inorganic-Silver,Fungicide,Heavy metalHerbicide,Plant GrowthRegulatorSilver orthophosphate7784-09-072510NA 679Microbiocide,Inorganic-Silver,(Ag3PO4)Fungicide,Heavy metalHerbicideSilver oxide (Ag4O4)1301-96-8#####NA 111Microbiocide,Inorganic-Silver,Fungicide,Heavy metalHerbicideSilver oxide (Ag4O4)155645-89-9#####NA 111Microbiocide,Inorganic-Silver,Fungicide,Heavy metalHerbicideSilver sodium hydrogenNA 116672560NA 164MicrobiocideInorganic-Silver,zirconium phosphateHeavy metal(Ag0.18Na0.57H0.25Zr2(PO4)3)Silver thiocyanate1701-93-568203NA 606Microbiocide,Inorganic-Silver,Fungicide,Heavy metalHerbicideSilver thiuronium acrylate co-53404-00-572701NA 681Microbiocide,Inorganic-Silver,polymerFungicide,Heavy metalHerbicideSilver zeolite130328-18-6#####NA 125MicrobiocideInorganic-Silver,Heavy metalSilver zinc zeolite130328-20-0#####NA 111MicrobiocideInorganic-Silver,Inorganic-Zinc,Heavy metalSilver, ionic14701-21-4NA 1695150Microbiocide,Inorganic-Silver,Fungicide,Heavy metalHerbicideSodium silver thiosulfateNA 1398NA 197NA 196HerbicideInorganic-Silver,Heavy metal2-Mercaptobenzothiazole, zinc155-04-4517051449Fungicide,Mercaptobenzothiazole,saltMicrobiocideInorganic-Zinc5-Chloro-2-53404-93-651709NA 427Microbiocide,Mercaptobenzothiazole,mercaptobenzothiazole, zincFungicideInorganic-ZincsaltBoric acid(H4B6O11), zinc12447-61-9#####5094FungicideInorganic-Zincsalt(1:2)Calcium-zinc LN 193NA 653NA 1203871N/AInorganic-Zinc(complex)Chromated zinc chlorideNA 1026878011187Insecticide,Inorganic-Herbicide,Chromium(VI),MicrobiocideInorganic-Zinc,Heavy metalCopper-zinc chromate complex1344-74-721003163Fungicide,Inorganic-WoodChromium(VI),PreservativeInorganic-Zinc,Heavy metal,Inorganic-CopperCopper-zinc sulfate complex55072-57-68102164FungicideInorganic-Zinc,Inorganic-CopperCopper-zinc sulfate complex,NA 959NA 3821751FungicideInorganic-Zinc,monohydrateInorganic-CopperCrag turf fungicide 53112001-20-621006NA 171FungicideInorganic-Cadmium,(Cd—Cu—Ca—Zn-Chromate)Inorganic-Chromium(VI),Inorganic-Zinc,Heavy metalEDTA, disodium zinc salt14025-21-9NA 2743189N/AInorganic-ZincLignin sulfonic acid, zinc saltNA 1014NA 1021768N/AInorganic-ZincLignin sulfonic acid, zinc,NA 1030NA 1261771N/AInorganic-Zincmanganese & iron saltsMancozeb223310014504211FungicideDithiocarbamate,Inorganic-ZincMetiram9006-42-214601493FungicideDithiocarbamate,Inorganic-Zinco-Phenylphenol, alkyl* amine-82010-74-064107NA 533MicrobiocidePhenols, Inorganic-zinc salt of *(100% C18)ZincPentachlorophenol, zinc salt2917-32-063008NA 510WoodChlorinated Phenol,Preservative,Inorganic-ZincMicrobiocide,Algaecide,FungicidePolyoxin D zinc salt146659-78-1#####NA 129FungicideInorganic-ZincPropineb12071-83-9#####NA 155Fungicide,Dithiocarbamate,MicrobiocideInorganic-ZincSilver zinc zeolite130328-20-0#####NA 111MicrobiocideInorganic-Silver,Inorganic-Zinc,Heavy metalZinc7440-66-6#####2310HerbicideInorganic-zincZinc 2,4,5-trichlorophenate136-24-364221NA 546N/AChlorinated Phenol,Inorganic-ZincZinc 2-ethyl hexoate136-53-8412033509N/AInorganic-ZincZinc 2-pyridinethiol-1-oxide13463-41-7880022128MicrobiocideInorganic-ZincZinc 8-quinolinolate13978-85-324005NA 196Fungicide,Inorganic-ZincMicrobiocideZinc abietate6798-76-1NA 1123506N/AInorganic-ZincZinc arsenate13464-44-313301NA 125Herbicide,Inorganic-Arsenic,Insecticide,Heavy metal,RodenticideInorganic-ZincZinc arsenite28837-97-013604NA 130Herbicide,Inorganic-Arsenic,Insecticide,Inorganic-Zinc,RodenticideHeavy metalZinc bacitracin1405-89-66309NA 87MicrobiocideInorganic-ZincZinc carbonate3486-35-9NA 1023507N/AInorganic-ZincZinc chloride7646-85-787801624MicrobiocideInorganic-ZincZinc dehydroabietylammonium53404-92-54211NA 75Fungicide,Inorganic-Zinc2-ethylhexanoateMicrobiocideZinc dodecyl benzene sulfonate12068-16-5NA 1123508Microbiocide,Soap, Inorganic-ZincAdjuvant,Fungicide,InsecticideZinc fluosilicate16871-71-9753071019InsecticideInorganic-ZincZinc formate557-41-587802NA 838N/AInorganic-ZincZinc hydroxide20427-58-1885013510N/AInorganic-ZincZinc isodecanoate30304-30-441222NA 355N/AInorganic-ZincZinc isononanoate5398-80-641212NA 353N/AInorganic-ZincZinc isooctanoate84082-93-941205NA 351N/AInorganic-ZincZinc mercury chromate22323-45-121004NA 170FungicideInorganic-Mercury,Inorganic-chromium(VI),Inorganic-Zinc,Heavy metalZinc naphthenate12001-85-3883011111WoodInorganic-ZincPreservative,Insecticide,Fungicide, Dogand CatRepellentZinc neodecanoate27253-29-897502NA 853N/AInorganic-ZincZinc oxide1314-13-288502666Fungicide,Inorganic-ZincAdjuvantZinc petroleum (C20-C30)68989-17-388503NA 841N/AInorganic-ZincsulfonateZinc phenol sulfonate127-82-289002NA 842N/AInorganic-ZincZinc phosphide1314-84-788601626RodenticideInorganic-ZincZinc resinate9010-69-977001NA 712N/AInorganic-ZincZinc silicateNA 13188103NA 176MicrobiocideInorganic-ZincZinc stearate557-05-1770023511N/AInorganic-ZincZinc sulfate7733-02-089001667Microbiocide,Inorganic-ZincHerbicideZinc sulfate, anhydrous7733-02-0890011852Microbiocide,Inorganic-ZincHerbicideZinc sulfate, basic68813-94-589101NA 843N/AInorganic-ZincZinc sulfate, monohydrate7446-19-7#####2995HerbicideInorganic-ZincZinc trichlorophenate30143-22-764213NA 543MicrobiocideChlorinated Phenol,Inorganic-ZincZineb12122-67-714506627FungicideDithiocarbamate,Inorganic-ZincZineb-ethylene thiuramNA 1465NA 217NA 216FungicideDithiocarbamate,disulfide adductInorganic-ZincZiram137-30-434805629Fungicide,Dithiocarbamate,Microbiocide,Inorganic-ZincDog and CatRepellentZiram, cyclohexylamine16509-79-8348061328Dog and CatDithiocarbamate,complexRepellent,Inorganic-ZincFungicide1-butoxy ethoxy-2-propanol124-16-3NA 1133074N/AAlcohol/Ether1-butoxy-2-propanol5131-86-8NA 4673075SolventAlcohol/Ether1-decanol112-30-1790381791Plant GrowthAlcohol/EtherRegulator1-Heptadecanol1454-85-9#####NA 150N/AAlcohol/Ether1-heptanol111-70-6NA 2053222N/AAlcohol/Ether1-hexanol111-27-3790473229N/AAlcohol/Ether1-Octanol111-87-579037NA 733Plant GrowthAlcohol/EtherRegulator,Herbicide2,6,8-trimethyl-4-nonanol123-17-1NA 1443303AdjuvantAlcohol/Ether2-(2-Butoxyethoxy)ethanol112-34-511502NA 117SolventAlcohol/Ether,Glycol Ether2-butoxyethanol111-76-21150189Fungicide,Alcohol/EtherMicrobiocide,Solvent2-ethoxyethanol110-80-5NA 1042554Fungicide,Alcohol/EtherMicrobiocide2-Ethyl-1-butanol97-95-0#####NA 148N/AAlcohol/Ether2-ethyl-1-hexanol10-47-6NA 2512560N/AAlcohol/Ether2-Ethyl-1-hexanol104-76-779098NA 767SolventAlcohol/Ether2-Phenylcyclohexanol1444-64-065002NA 550N/AAlcohol/Ether2-Phenylethanol60-12-81503NA 62N/AAlcohol/Ether3,3,5-trimethyl cyclohexanol116-02-9NA 9823493N/AAlcohol/Ether3-phenoxybenzyl alcohol13826-35-2NA 6512771N/AAlcohol/Ether4-Methyl-2-pentanol108-11-2#####NA 157N/AAlcohol/EtherAlcohols, C4-C12, normalNA 392NA 7132067Solvent,Alcohol/EtherMicrobiocideAlcohols, C6-1268603-15-6790295072Microbiocide,Alcohol/EtherSolventAlcohols, C8-1085566-12-7790595073Microbiocide,Alcohol/EtherSolventAlkanols (ave. C6), mixedNA 394NA 7161536AdjuvantAlcohol/EtherAlkylaryl polyether alcoholNA 657NA 121878AdjuvantAlcohol/EtherAllyl alcohol107-18-6684013023HerbicideAlcohol/EtherBenzyl alcohol100-51-69502915Insecticide,Alcohol/EtherFungicideButyl alcohol78-92-215021482SolventAlcohol/EtherCetyl alcohol36653-82-415082449N/AAlcohol/EtherCinnamyl alcohol104-54-140512NA 343InsecticideAlcohol/EtherCyclobutaneethanol, 1-methyl-30820-22-5#####NA 922N/AAlcohol/Ether2-(1-methylethenyl)-,cis-Cyclohexanol108-93-0259043121SolventAlcohol/EtherDenatured ethanolNA 1033NA 1292102SolventAlcohol/EtherDimethyl ether115-10-6NA 1322517SolventAlcohol/EtherEthyl alcohol64-17-515018Microbiocide,Alcohol/EtherSolvent,Adjuvant,MolluscicideEthylene oxide75-21-842301277FumigantAlcohol/EtherFatty alcohols (100% C4-C10)NA 126NA 2413654AdjuvantAlcohol/EtherFatty alcohols (55.10% C10,NA 126579089NA 173Plant GrowthAlcohol/Ether42.88% C8, 1.01% C6, 1.01%Regulator,C12)AdjuvantFatty alcohols (65% C12, 26%67762-41-879056NA 744AdjuvantAlcohol/EtherC14, 8% C16, 1% C10)Hydrocinnamyl alcohol122-97-440511NA 342N/AAlcohol/Etheri-Nonyl alcohol3452-97-9#####NA 153N/AAlcohol/EtherIsobutyl alcohol78-83-115072622SolventAlcohol/EtherIsodecyl alcohol25339-17-7NA 1683242SolventAlcohol/EtherIsopropyl alcohol67-63-047501342Microbiocide,Alcohol/EtherSolventIsostearyl alcohol27458-93-1NA 1562627AdjuvantAlcohol/EtherLauryl alcohol112-53-815092343Pheromone,Pheromone,AdjuvantAlcohol/EtherMethanol67-56-1538011018Solvent,Alcohol/EtherAdjuvant,MicrobiocideMethoxypropanol107-98-2NA 902675SolventAlcohol/EtherMyristyl alcohol112-72-115102344Pheromone,Alcohol/EtherFragrancen-Butyl alcohol71-36-3NA 4683077SolventAlcohol/Ethern-Decyl alcohol112-30-1790383124Plant GrowthAlcohol/EtherRegulatorn-Propoxy propanol30136-13-1NA 7982837SolventAlcohol/Ethern-Propyl alcohol71-23-8475021603SolventAlcohol/EtherOleyl alcohol143-28-2NA 93313AdjuvantAlcohol/EtherPropargyl alcohol107-19-768702NA 609BreakdownAlcohol/EtherproductPropylene oxide75-56-942501508FumigantAlcohol/Ethersec-Butanol75-65-01505NA 64SolventAlcohol/EtherSec-butyl alcohol78-92-215023078SolventAlcohol/EtherStearyl alcohol112-92-5NA 1102892AdjuvantAlcohol/EtherTetrahydro furfuryl alcohol97-99-4NA 9453471SolventAlcohol/Ether(2-150-39-039108NA 330AdjuvantChelating agentHydroxyethyl)ethylenediaminetriacetic acidDimethamine EDTANA 167NA 3193159AdjuvantChelating agentEDTA60-00-4391011702AdjuvantChelating agentEDTA, ammonium salt7379-26-239117889AdjuvantChelating agentEDTA, diethanolamine salt68133-37-9NA 2733187AdjuvantChelating agentEDTA, disodium salt139-33-3391152101Herbicide,Chelating agentAdjuvantEDTA, disodium salt139-33-339115954Herbicide,Chelating agentAdjuvantEDTA, iron chelateNA 890NA 1703240HerbicideChelating agentEDTA, monoethanolamine salt7379-26-2391172013AdjuvantChelating agentEDTA, monopotassium salt7379-27-339111NA 331AdjuvantChelating agentEDTA, potassium saltNA 891NA 1703350AdjuvantChelating agentEDTA, sodium salt17421-79-3391031757AdjuvantChelating agentEDTA, tetrapotassium salt5964-35-2391181054AdjuvantChelating agentEDTA, tetrasodium salt64-02-839107759AdjuvantChelating agentEDTA, trisodium salt150-38-939110953AdjuvantChelating agentEthanolamine63517-71-539116NA 334Adjuvant,Chelating agentethylenediaminetetraacetateFungicideN-(2-hydroxyethyl) ethylene139-89-939109911Microbiocide,Chelating agentdiamine triacetic acid, trisodiumAdjuvantsaltNitrilotriacetic acid139-13-9NA 228NA 228AdjuvantChelating agentNitrilotriacetic acid, sodium10042-84-9#####NA 121AdjuvantChelating agentsaltSodium N-(2-53404-54-939121NA 335AdjuvantChelating agenthydroxyethyl)ethylenediaminetriacetateTetra(monoethanolamine)53404-52-739112NA 332Adjuvant,Chelating agentethylenediaminetetraacetateAdjuvantTriethylamine EDTANA 790NA 1463486AdjuvantChelating agentTriethylamine nitrilo triacetateNA 537NA 9783487AdjuvantChelating agentTripotassium17572-97-3391131177AdjuvantChelating agentethylenediaminetetraacetateTrisodium nitrilo triacetate5064-31-3391061121AdjuvantChelating agent2,4,5-T, butoxyethanol ester2545-59-782053819HerbicideChlorophenoxy acidor ester, Glycol Ether2,4-D, butoxyethanol ester1929-73-330053802HerbicideChlorophenoxy acidor ester, Glycol Ether2-(2-Butoxyethoxy)ethanol112-34-511502NA 117SolventAlcohol/Ether,Glycol Ether4-(2,4-DB), butoxyethanol32357-46-330853837HerbicideChlorophenoxy acidesteror ester, Glycol EtherAlkylaryl polyglycol etherNA 319NA 5991264AdjuvantPolyalkyloxyCompound, GlycolEtherCinoxate104-28-976604NA 706N/AGlycol EtherDichlorprop, butoxyethanol53404-31-231453923Plant GrowthChlorophenoxy acidesterRegulator,or ester, Glycol EtherHerbicideDiethylene glycol monoethyl111-90-0115042505Adjuvant,Glycol EtheretherSolventDiethylene glycol monomethyl111-77-3422042506Adjuvant,Glycol EtheretherSolventEthoxyethoxyethyl 2,4-53404-36-730058NA 245HerbicideChlorophenoxy aciddichlorophenoxyacetateor ester, Glycol EtherEthyl amino benzoate111-15-9NA 2603192N/AGlycol EtherEthylene glycol, mono-butyl111-76-2115011880Solvent,Glycol EtheretherAdjuvantHaloxyfop-etotyl (unstated87237-48-7NA 200NA 199HerbicideAryloxyphenoxystereochemistry)propionic acid,Glycol EtherMCPA, butoxyethanol ester19480-43-430553785HerbicideChlorophenoxy acidor ester, Glycol EtherSilvex, butoxyethanol ester19398-13-182553828HerbicideChlorophenoxy acidor ester, Glycol EtherTriclopyr, butoxyethyl ester64700-56-7#####2170HerbicideChloropyridinyl,Glycol Ether(Decyl oxy) poly (oxy9038-29-3NA 1173636AdjuvantPolyalkyloxyethylene) poly (oxy propylene)Compound(Octyl oxy) poly (oxyethylene)61827-84-7NA 1023707AdjuvantPolyalkyloxypoly (oxypropylene)Compound2,6,8-trimethyl-4-nonyloxyNA 1162NA 1755599AdjuvantPolyalkyloxypolyethylene oxyethanolCompound4-nonyl phenoxy polyNA 805NA 1493698Soap/Surfactant,Polyalkyloxy(ethylene oxy) ethyl phosphate,AdjuvantCompoundmagnesium salta-(p-nonylphenyl)-omega-NA 27NA 402066MicrobiocidePolyalkyloxyhydroxypoly (oxyethylene)Compoundwith an average of 4.2 moles ofethylene oxide.the nonly groupis a propylenea-(p-nonylphenyl)-omega-NA 28NA 412052MicrobiocidePolyalkyloxyhydroxypoly (oxyethylene)Compoundwith an averageof 9-10 molesof ethylene oxideAlkenoic acid poly oxyalkyleneNA 396NA 7182364AdjuvantPolyalkyloxyether & alkyl poly oxyalkyleneCompoundetherAlkoxy poly (ethyleneoxy)NA 286NA 5551390Adjuvant,Polyalkyloxyethyl phosphateSoap/SurfactantCompoundAlkyl (100% C10-C13) oxyNA 288NA 5603575Adjuvant,Polyalkyloxypoly (ethylene oxy) ethylSoap/SurfactantCompoundphosphate, mono-Alkyl (100% C10-C14) oxy68585-36-4NA 5793574Adjuvant,Polyalkyloxypoly (ethylene oxy) ethylSoap/SurfactantCompoundphosphateAlkyl (100% C11-C15)68131-40-8790843572Insecticide,Polyalkyloxyphenoxypoly (ethylene oxy)Fungicide,CompoundethanolAvicide,AdjuvantAlkyl (C8,C10) polyglycoside68515-73-1NA 1544015AdjuvantPolyalkyloxyCompoundAlkyl and alkylaryl polyNA 398NA 7201706AdjuvantPolyalkyloxy(oxyethylene) glycols, mixedCompoundAlkyl aryl alkoxylateNA 314NA 5942366AdjuvantPolyalkyloxyCompoundAlkyl aryl polyoxyalkane etherNA 323NA 6032370AdjuvantPolyalkyloxyand free fatty acidsCompoundAlkyl oxy poly (ethyleneoxy)NA 679NA 1251715Adjuvant,Polyalkyloxyethyl phosphateSoap/SurfactantCompoundAlkyl oxy polyethoxy ethanolNA 306NA 5782048AdjuvantPolyalkyloxyCompoundAlkyl oxy-polyoxyethylene andNA 289NA 5612136AdjuvantPolyalkyloxyalkyl phenyloxy-CompoundpolyoxyethyleneAlkyl phenoxypoly (ethoxy)NA 291NA 5631173AdjuvantPolyalkyloxyethanolCompoundAlkyl phenyl poly (ethoxy)NA 294NA 5661064AdjuvantPolyalkyloxyethanolCompoundAlkyl polyethylene glycol etherNA 668NA 1231376Adjuvant,PolyalkyloxySoap/SurfactantCompoundAlkyl polyoxy alkylene etherNA 295NA 5672123AdjuvantPolyalkyloxyCompoundAlkyl polyoxy ethylene ether,NA 592NA 1072014AdjuvantPolyalkyloxydiphosphoric acid esterCompoundAlkyl polyoxy ethylene ether,NA 296NA 5682377AdjuvantPolyalkyloxyfree fatty acidsCompoundAlkyl polyoxy ethylene ether,NA 694NA 1272015AdjuvantPolyalkyloxymonophosphoric acid esterCompoundAlkyl polyoxy ethylene ethers,NA 297NA 5692158AdjuvantPolyalkyloxypolymerized resins and fattyCompoundacidsAlkyl polyoxy ethylene glycolsNA 285NA 5542051AdjuvantPolyalkyloxyCompoundAlkylaryl hydroxypolyNA 316NA 5962037AdjuvantPolyalkyloxy(oxyethylene) ethanolCompoundAlkylaryl poly(oxyethylene)NA 315NA 595748AdjuvantPolyalkyloxyglycolCompoundAlkylaryl polyalkoxylatedNA 705NA 1292174AdjuvantPolyalkyloxyalcoholsCompoundAlkylaryl polyethoxy ethanolNA 714NA 1302368Adjuvant,PolyalkyloxyphosphateSoap/SurfactantCompoundAlkylaryl polyethoxyethanolNA 912NA 1745323AdjuvantPolyalkyloxysulfatesCompoundAlkylaryl polyethylene glycolNA 318NA 5982198Adjuvant,PolyalkyloxyetherSoap/SurfactantCompoundAlkylaryl polyglycol esterNA 1470NA 218NA 218AdjuvantPolyalkyloxyCompoundAlkylaryl polyglycol etherNA 319NA 5991264AdjuvantPolyalkyloxyCompound, GlycolEtherAlkylaryl polyoxy glycolNA 322NA 6022369AdjuvantPolyalkyloxyCompoundAlkylaryl polyoxyethyleneNA 320NA 600881AdjuvantPolyalkyloxyetherCompoundAlkylaryl polyoxyethyleneNA 321NA 6012024Adjuvant,Polyalkyloxyglycol phosphate esterSoap/SurfactantCompoundAlkylaryl poyloxyethyleneNA 671NA 1241507AdjuvantPolyalkyloxyethanolCompoundAlkylpoly glycol etherNA 292NA 5641172AdjuvantPolyalkyloxyCompoundAllyl oxy poly ethylene glycolNA 279NA 5452376N/APolyalkyloxymonoallyl acetateCompoundAlpha (para-tert-butyl phenyl)-NA 235NA 4631605AdjuvantPolyalkyloxyomega-hydroxypolyCompound(oxyethylene)-Alpha (para-tert-butylphenyl)-NA 234NA 4621786AdjuvantPolyalkyloxyomega-hydroxypolyCompound(oxyethylene)Alpha-(omega-sec-butylNA 231NA 4521885AdjuvantPolyalkyloxyphenylpoly (oxypropylene))-Compoundomega-hydroxypolyAlpha-(p-(1,1,3,3-tetramethylNA 609NA 1111932AdjuvantPolyalkyloxybutyl) phenyl)-omega-hydroxypolyCompoundAlpha-(p-nonylphenyl)-omega-NA 745NA 1352710AdjuvantPolyalkyloxyhydroxypoly (oxypropylene)CompoundAlpha-(para-nonyl phenyl)-NA 18NA 311649AdjuvantPolyalkyloxyomega-hydroxypolyCompound(oxyethylene)Alpha-alkyl (43% C10,NA 684NA 1261834MicrobiocidePolyalkyloxy30% C14, 12% C12, 10% C16,Compound5% C18) poly (oxyethylene)poly (oxypropylene) - I2complexAlpha-alkyl (C10-C12)-omega-NA 307NA 5822077AdjuvantPolyalkyloxyhydroxypoly (oxyethylene)CompoundAlpha-alkyl (C10-C18)-NA 301NA 5731700AdjuvantPolyalkyloxyomega-hydroxypolyCompound(oxyethylene) sulfate150 solvent neutral BP 901NA 747NA 1362724InsecticidePetroleum derivativebase oilAlkylated aromatic petroleum68919-17-554001NA 451Insecticide,Petroleum derivativeoilAdjuvantAmoco 6342NA 715NA 1312384N/APetroleum derivativeAnthracene oil120-12-7NA 185NA 184Insecticide,Petroleum derivativeHerbicide,RodenticideAromatic 100NA 269NA 5242394Insecticide,Petroleum derivativeSolventAromatic 150NA 716NA 1312395Insecticide,Petroleum derivativeSolventAromatic 20064742-94-566022396Insecticide,Petroleum derivativeSolventAsphalt solids8052-42-4220011140Pruning AidPetroleum derivativeBitumen8052-42-422002NA 171N/APetroleum derivativeCandle waxNA 227NA 4402443N/APetroleum derivativeChevron 100 neutral oil68602-80-266012456InsecticidePetroleum derivativeChevron base oil “C”NA 224NA 4312455InsecticidePetroleum derivativeChevron solvent 425NA 722NA 1322457SolventPetroleum derivativeCoal tar distillate boiling65996-91-061015042Insecticide,Petroleum derivativebetween 270-300 deg C.HerbicideCoal tar hydrocarbons8007-45-2220031719WoodPetroleum derivativePreservativeCoal tar neutral oils and coal65996-82-925001144Insecticide,Petroleum derivativetar acid combinationsHerbicideCoal tar phenols1319-77-3221011720N/APetroleum derivative,PhenolsCoal tar pitch >35165996-93-2#####NA 106InsecticidePetroleum derivativedeg. C.(AWPI)Conoco LPANA 195NA 3862478N/APetroleum derivativeCreosote8001-58-925004171WoodPetroleum derivativePreservativeCreosote oil (note: derived61789-28-425003NA 203WoodPetroleum derivativefrom any source)Preservative,FungicideCumene98-82-8NA 1053116N/APetroleum derivativeCyclohexane110-82-7259012087SolventPetroleum derivativeDiesel fuel no. 268476-34-6635143923Insecticide,Petroleum derivativeAdjuvantEthyl benzene100-41-4NA 1423197N/APetroleum derivativeEthylene74-85-141901270Plant GrowthPetroleum derivativeRegulatorFuel oil #170892-10-363511NA 520N/APetroleum derivativeFuel oil #268476-30-263505NA 517N/APetroleum derivativeFuel oil #468476-31-363512NA 521N/APetroleum derivativeFuel oil #668553-00-463513NA 522N/APetroleum derivativeGasolineNA 945NA 2211899N/APetroleum derivativeHeavy oil (coal) 301-350 deg. C.90640-86-1#####NA 106N/APetroleum derivative(AWPI)Hydrotreated paraffinic solventNA 91NA 1822601SolventPetroleum derivativeIsobutane75-28-5971012621PropellantPetroleum derivativeIsoparaffin, C11-C12NA 85NA 1632623N/APetroleum derivativeIsoparaffin, C12-C14NA 86NA 1642624N/APetroleum derivativeIsoparaffinic hydrocarbons64771-72-8#####1641N/APetroleum derivativeIsopentane78-78-4NA 1653244SolventPetroleum derivativeJet fuel94114-58-663515NA 523Insecticide,Petroleum derivativeSolventKerosene8008-20-6635012071InsecticidePetroleum derivativeKM spray oilNA 78NA 1502631N/APetroleum derivativeLigroin8032-32-4635062642SolventPetroleum derivativeLow molecular weight64642-47-8NA 1735252InsecticidePetroleum derivativeparaffinic oilMCIAL code 40164742-55-8635032045Insecticide,Petroleum derivativeAdjuvantMineral oil8012-95-163502401Insecticide,Petroleum derivativeAdjuvantMineral oil, petroleum64741-89-5635033846Herbicide,Petroleum derivativedistillates, solvent refined lightPlant GrowthRegulator,Insecticide,AdjuvantMineral oil, petroleum extract,64724-04-7NA 1713847Insecticide,Petroleum derivativeheavy paraffinic distillateAdjuvantMineral seal oilNA 930NA 672687Insecticide,Petroleum derivativeAdjuvantMineral spirits8032-32-4635062688Insecticide,Petroleum derivativeSolvent,Fungiciden-Hexane110-54-3NA 1033227SolventPetroleum derivativeNaphtha, heavy aromatic64742-94-566021717Insecticide,Petroleum derivativeSolventOrchex 796 oilNA 899NA 1725179Insecticide,Petroleum derivativeAdjuvantParaffin wax8002-74-2NA 1071214RodenticidePetroleum derivativeParaffin waxes (petroleum)64742-51-4NA 6943545N/APetroleum derivativehydrotreatedParaffin waxes and61788-76-9NA 6933721N/APetroleum derivativehydrocarbon waxes,chlorinatedPentane109-66-098001469SolventPetroleum derivativePetroleum derivative resin64742-16-1114011411N/APetroleum derivativePetroleum distillates222737863503763InsecticidePetroleum derivativePetroleum distillates, aliphatic2227378635032768Insecticide,Petroleum derivativeAdjuvant,SolventPetroleum distillates, aromatic68477-31-665011814Solvent,Petroleum derivativeHerbicide,InsecticidePetroleum distillates, refined64741-51-1NA 6542106InsecticidePetroleum derivativePetroleum hydrocarbons8012-95-163502473Insecticide,Petroleum derivativeSolventPetroleum jelly2229873#####1443InsectPetroleum derivativeRepellent,AdjuvantPetroleum naphthenic oilsNA 990NA 6552107Insecticide,Petroleum derivativeAdjuvantPetroleum oil, unclassified68815-10-1NA 121765Insecticide,Petroleum derivativeHerbicide,Fungicide,AdjuvantPetroleum sulfonates61789-85-3#####766N/APetroleum derivativePetroleum, unrefined2227378635031730Insecticide,Petroleum derivativeAdjuvantPolybutenes9003-29-6114021040RodenticidePetroleum derivativePolyisobutylene9003-27-4114031561RodenticidePetroleum derivativePropane74-98-6NA 1092832PropellantPetroleum derivativePropylene1150-70-1NA 8002838N/APetroleum derivativeSolvent naphtha (coal), 150-20065996-79-4#####NA 106SolventPetroleum derivativedeg. C.Solvent naphtha (petroleum),64742-95-6868033804SolventPetroleum derivativelight aromaticSummer oilNA 1468NA 218NA 218Insecticide,Petroleum derivativeAdjuvantSun superior spray oil 7NNA 769NA 1392902Insecticide,Petroleum derivativeAdjuvantSynthetic beeswaxNA 509NA 9202910N/APetroleum derivativeTarNA 131222004NA 176WoodPetroleum derivativePreservativeTar acid oilNA 1041NA 1392914InsecticidePetroleum derivativeToluene108-88-3806011281SolventPetroleum derivativeTurpentine8006-64-284501605Insecticide,Petroleum derivativeAdjuvantWhite mineral oil8042-47-563510NA 519Insecticide,Petroleum derivativeAdjuvantWinter oilNA 1472NA 219NA 218AdjuvantPetroleum derivativeXylene1330-20-786802622Solvent,Petroleum derivativeMicrobiocideXylene range aromatic solvent68920-06-9NA 102862Solvent,Petroleum derivativeInsecticide3-(3-hydroxypropyl)-heptamethylNA 90NA 1782610AdjuvantSiliconetrisiloxane, ethoxylated,acetateCompounded siliconeNA 703NA 1292124AdjuvantSiliconeDimethyl poly sloxane63148-62-9NA 1041861Insecticide,SiliconeAdjuvantDimethyl silicone fluidNA 696NA 1282028AdjuvantSiliconeemulsionDow Corning antifoam Y-30NA 146NA 2802539AdjuvantSiliconeemulsionDow Corning DB-110A-NA 577NA 1042540AdjuvantSiliconeantifoam emulsionHeptamethyltrisiloxane67674-67-3NA 1534009AdjuvantSiliconeethoxylated (8 EO)Methyl silicone resins9016-00-6NA 773689AdjuvantSiliconeMethylated silica67762-90-7NA 1735292N/ASiliconeOrgano/modified polysiloxane37281-78-0NA 1533997AdjuvantSiliconeOrganosilicone, polyoxyalkylene67762-85-0NA 1735231AdjuvantSiliconeether copolymerPolyalkene oxide modified27306-78-1NA 1463520AdjuvantSiliconeheptamethyl trisiloxanePolyalkyleneoxide modifiedNA 904NA 1725203AdjuvantSiliconepolydimethyl-siloxanePolyether modifiedNA 906NA 1725223AdjuvantSiliconepolysiloxanePolysiloxaneNA 1337NA 1805718AdjuvantSiliconeSiliconeNA 815NA 1503796AdjuvantSiliconeSilicone defoamerNA 462NA 8261917AdjuvantSiliconeSilicone mold release agent SMNA 463NA 8272854N/ASilicone2140Silicone-polyether copolymer27306-78-1NA 1513841AdjuvantSiliconeTrimethyl siloxy stearateNA 541NA 9872965N/ASilicone1,1,2,3-tetramethyl butylamineNA 1010NA 9483472Microbiocide,Soapdodecyl benzene sulfonateAdjuvant,Fungicide,Insecticide1,3-propane diamine dodecylNA 1021NA 1153369Microbiocide,Soapbenzene sulfonateAdjuvant,Fungicide,Insecticide2,2-oxybis (4-dodecyl benzeneNA 1161NA 1751741Microbiocide,Soapsulfonate)Adjuvant,Fungicide,Insecticide2-((2-amino ethyl) amino)68084-55-9NA 5383034Microbiocide,Soapethanol dodecyl benzeneAdjuvant,sulfonateFungicide,InsecticideAlkanolamide surfactantsNA 911NA 1745322Soap/Surfactant,SoapAdjuvantAlkyl* sodium benzene68411-30-3#####NA 126Microbiocide,Soapsulfonate *(56% C11, 33% C12,Adjuvant,7% C10, 4% C13)Fungicide,InsecticideAmmonium lauryl sulfate2235-54-3790281017Adjuvant,SoapInsecticide,Microbiocide,FungicideAmmonium oleate544-60-5317031230Adjuvant,SoapInsecticideAmmonium tall oil fatty acid544-60-531703995Adjuvant,SoapsoapInsecticideBenzene, 1,1′-oxybis-119345-04-9NA 1473561Microbiocide,Soaptetrapropylene derivatives,Adjuvant,sulfonated, sodiumFungicide,InsecticideButylamine dodecyl benzene12068-09-6NA 4693079Microbiocide,SoapsulfonateAdjuvant,Fungicide,InsecticideCoconut oil soapNA 199NA 3912088Adjuvant,SoapInsecticide,Soap/SurfactantDEA-dodecyl benzene26545-53-9790153123Microbiocide,SoapsulfonateAdjuvant,Fungicide,InsecticideDiethylamine salt of coconutNA 210NA 4021066Adjuvant,Soapfatty acidSoap/SurfactantDiisopropylamine dodecyl29061-61-8NA 3273156Microbiocide,Soapbenzene sulfonateAdjuvant,Fungicide,InsecticideDimethylalmine propylamineNA 953NA 3183162Microbiocide,Soaptridecyl benzene sulfonateAdjuvant,Fungicide,InsecticideDimethylamine dodecylNA 954NA 3243161Microbiocide,Soapbenzene sulfonateAdjuvant,Fungicide,InsecticideDisodium 2,2′-oxybis(4-5136-51-6790033175Microbiocide,Soapdodecylbenzene)sulfonateAdjuvant,Fungicide,InsecticideDisodium 4-dodecyl-2,4′-7575-62-4790023172Microbiocide,Soapoxydibenzene sulfonateAdjuvant,Fungicide,InsecticideDodecyl alkyl sulfonateNA 284NA 5531599AdjuvantSoapDodecylbenzene sulfonic acid27176-87-098002941Adjuvant,SoapMicrobiocide,InsecticideEthylene diamine dodecyl12068-06-3NA 2573200Microbiocide,Soapbenzene sulfonateAdjuvant,Fungicide,InsecticideFatty acid estersNA 1358NA 193NA 192Plant GrowthSoapRegulator,Insecticide,AdjuvantFree fatty acids and/or amine84776-33-0318011198Herbicide, DeerSoapsaltsRepellent,Fungicide,InsecticideHydrogenated wax, neutralNA 93NA 1871368Adjuvant,Soapwax and alkali soaps of fattyInsecticideacidsIsopropylamine26264-05-1790303247Microbiocide,Soapdodecylbenzene sulfonateAdjuvant,Fungicide,InsecticideLauryl sulfate saltsNA 937NA 1372637Adjuvant,SoapInsecticide,Microbiocide,FungicideLinear alkyl sulfonate,NA 283NA 5521836AdjuvantSoappotassium saltMagnesium lauryl sulfate435950790171718Adjuvant,SoapInsecticide,Microbiocide,FungicideMannitan coconut oil ester26545-55-0NA 1063680Adjuvant,SoapSoap/SurfactantMonoethanolamine dodecyl26545-53-9790151890Microbiocide,Soapbenzene sulfonateAdjuvant,Fungicide,InsecticideN,N-dimethyl-1,3-propaneNA 950NA 3053168Microbiocide,Soapdiamine dodecyl benzeneAdjuvant,sulfonateFungicide,InsecticideNaphthenic soap61790-13-4#####1806Adjuvant,SoapInsecticideOleic acid, methyl ester112-62-9NA 52266AdjuvantSoapOleic acid, potassium salt143-18-079095865AdjuvantSoapOleic and linoleic acid, mixedNA 4NA 61807AdjuvantSoappotassium saltsOrganic phosphate esterNA 1NA 12725Soap/Surfactant,SoapsurfactantAdjuvantPara-alkyl (C9-C13) benzene25155-30-0790101739Microbiocide,Soapsulfonic acid, sodium saltAdjuvant,Fungicide,InsecticidePhenyl 2-trimethylammonium22232-15-1#####NA 125Microbiocide,Soapethanesulfonate methyl sulfateAdjuvant,Fungicide,InsecticidePotash fish soap68154-69-879040496Adjuvant,SoapInsecticidePotash soap61790-44-1#####1596Herbicide,SoapInsecticide,AdjuvantPotassium alkyl benzene27177-77-179008994Microbiocide,SoapsulfonatesAdjuvant,Fungicide,InsecticidePotassium dodecylbenzene27177-77-1790081027Microbiocide,SoapsulfonateAdjuvant,Fungicide,InsecticidePotassium laurate10124-65-979021901Adjuvant,SoapInsecticide,Microbiocide,Fungicide,Soap/SurfactantPotassium laurate and myristateNA 999NA 7802825Adjuvant,SoapsoapsInsecticide,Microbiocide,FungicidePotassium laurate, other relatedNA 1125NA 16690901Adjuvant,SoapInsecticide,Microbiocide,FungicidePotassium lauryl sulfate4706-78-9NA 7813353AdjuvantSoapPotassium myristate13429-27-179022902AdjuvantSoapPotassium soap of coconut10124-65-979021903Adjuvant,Soapfatty acidInsecticide,Microbiocide,Fungicide,Soap/SurfactantPotassium soap of tall oil fatty10124-65-9790211409Adjuvant,SoapacidInsecticide,Fungicide,MicrobiocidePotassium stearate593-29-3NA 7843361AdjuvantSoapShampoo baseNA 460NA 8223795AdjuvantSoapSoap68952-95-479009772Microbiocide,SoapInsecticide,Deer RepellentSodium alkyl* benzene26856-61-179087NA 760Microbiocide,Soapsulfonate *(100% C9)Adjuvant,Fungicide,InsecticideSodium benzene sulfonate515-42-4NA 109974Microbiocide,SoapAdjuvant,Fungicide,InsecticideSodium decyl benzene1322-98-1790883394Microbiocide,SoapsulfonateAdjuvant,Fungicide,InsecticideSodium di (1-alkenyl) phenoxy39354-74-0790601373AdjuvantSoapbenzene disulfonateSodium dodecylbenzene25155-30-079010774Microbiocide,SoapsulfonateAdjuvant,Fungicide,InsecticideSodium laurate629-25-479026NA 732Adjuvant,SoapInsecticide,Microbiocide,FungicideSodium lauryl ether diglycolNA 1471NA 219NA 218AdjuvantSoapsulfateSodium lauryl ether sulfate9004-82-4790543799Adjuvant,SoapInsecticide,Microbiocide,Fungicide,Soap/SurfactantSodium lauryl sulfate151-21-379011907Adjuvant,SoapInsecticide,Microbiocide,FungicideSodium methylundecyl27987-00-479053NA 742Microbiocide,SoapbenzenesulfonateAdjuvant,Fungicide,InsecticideSodium mono (1-alkenyl)39354-74-0790601372AdjuvantSoapphenoxy benzene disulfonateSodium n-decyl sulfate142-87-079077NA 754AdjuvantSoapSodium N-methyl-N-oleylNA 1004NA 8543419Adjuvant,SoaplaurateInsecticide,Microbiocide,FungicideSodium nonanoyloxybenzene91129-43-8890535137Microbiocide,SoapsulfonateAdjuvant,Fungicide,InsecticideSodium octylbenzene sulfonate28675-11-879057NA 745Microbiocide,SoapAdjuvant,Fungicide,InsecticideSodium tallow soapNA 473NA 8703802Adjuvant,SoapInsecticideSodium tetradecyl sulfate1191-50-0NA 1103446AdjuvantSoapSodium tridecylbenzene26248-24-879072NA 752Microbiocide,SoapsulfonateAdjuvant,Fungicide,InsecticideSodium triisopropyl1323-19-9NA 8723448Insecticide,Soapnaphthalene sulfonateFungicide,Microbiocide,AdjuvantSodium triphenyl benzeneNA 1006NA 8733449Microbiocide,SoapsulfonateAdjuvant,Fungicide,InsecticideSodium xylene sulfonate1300-72-779019909AdjuvantSoapSodium-1-octane sulfonate5324-84-5NA 8593886AdjuvantSoapSoybean fatty acids, tert amineNA 480NA 8841308AdjuvantSoapsaltStrontium dodecyl benzene12068-15-4NA 9063456Microbiocide,SoapsulfonateAdjuvant,Fungicide,InsecticideSulfonated petroleum soap61789-62-679012NA 729Adjuvant,SoapInsecticideSulfuric acid, monododecyl151-21-3790112901Adjuvant,Soapester sodium saltInsecticide,Microbiocide,FungicideSurfactant blendNA 1515NA 223NA 222Soap/Surfactant,SoapAdjuvantSurfactant mixtureNA 1516NA 223NA 223Soap/Surfactant,SoapAdjuvantTallow soapNA 607NA 1101499Adjuvant,SoapInsecticideTriethanolamine27323-41-779020984Microbiocide,Soapdodecylbenzene sulfonateAdjuvant,Fungicide,InsecticideZinc dodecyl benzene sulfonate12068-16-5NA 1123508Microbiocide,Soap, Inorganic-ZincAdjuvant,Fungicide,InsecticideCane syrupNA 228NA 4413598N/ACarbohydrateComplex carbohydrate polymerNA 834NA 1544027AdjuvantCarbohydratederivativeCorn syrupNA 580NA 1053628BaitCarbohydrateCornstarchNA 800NA 1483627N/ACarbohydrateDextrose50-99-7NA 3603129N/ACarbohydrateFructose7660-25-5NA 1775742N/ACarbohydrateHoneyNA 734NA 1342595N/ACarbohydrateInvert sugar8013-17-0NA 1713672BaitCarbohydrateInvert syrupNA 941NA 1723673BaitCarbohydrateLactose63-42-3NA 1411400N/ACarbohydrateMalt extract8002-48-0NA 1342659N/ACarbohydrateMolassesNA 40NA 69744BaitCarbohydratePolysaccharide polymerNA 702NA 1292112AdjuvantCarbohydrateSorbitol50-70-4NA 2141629N/ACarbohydrateStarch9005-84-9NA 8981821N/ACarbohydrateStarch-G-poly (acrylamide-co-NA 494NA 8992888N/ACarbohydratesodium acrylate)Sugar57-50-123708BaitCarbohydrateSweet n′ neat 45 spray driedNA 634NA 1163565N/ACarbohydratehoney powderValidamycin37248-47-8NA 190NA 189FungicideCarbohydratealpha-CelluloseNA 1537NA 225NA 224InsecticideCellulose derivativeCarbo methoxy ether cellulose,9004-32-4#####2446InsecticideCellulose derivativesodium saltCellulose9004-34-6NA 4323100N/ACellulose derivativeCellulose ethyl hydroxy ethyl9004-58-4NA 1133101N/ACellulose derivativeetherEthyl cellulose9004-57-3NA 2643652N/ACellulose derivativeHydroxyethyl cellulose9004-62-0462011511N/ACellulose derivativeHydroxypropyl methyl9004-65-3NA 1791969N/ACellulose derivativecelluloseMethyl cellulose9004-67-5NA 851205N/ACellulose derivativeMicrocrystalline cellulose9004-34-6NA 632686N/ACellulose derivativeNitrocellulose9004-70-099601NA 867N/ACellulose derivative(2-41289-08-1#####NA 101N/AUnclassifiedchloroethyl)methylbis(phenylmethoxy)silane1% verde green solutionNA 553NA 1002982DyeUnclassified1,2-dimethyl hydrazine540-73-0NA 1423165N/AUnclassified1,2-epoxy butane106-88-7NA 1423190N/AUnclassified1,3-butadiene106-99-0NA 4712431N/AUnclassified1-((4-methyl-2-nitrophenyl)NA 43NA 802682N/AUnclassifiedazo) naphthalenol1-methyl pyrrolidine120-94-5NA 753287N/AUnclassified1-Pentanethiol110-66-7#####NA 872N/AUnclassified2,2′-octadecyl imino diethanol10213-78-2NA 203306N/AUnclassified2,2′-oxybis (4,4,6-trimethyl-14697-50-812402792MicrobiocideUnclassified1,3,2-dioxaborinane)2-butanone oxime96-29-7NA 4743071N/AUnclassified2-chloropyridine-N-oxideNA 219NA 4172466N/AUnclassified2-ethyl hexanoic acid149-57-5#####3228N/AUnclassified2-ethyl hexyl acrylate103-11-7NA 2522115N/AUnclassified2-heptanone110-43-0NA 2063223N/AUnclassified2-hydroxy-4-n-octylNA 572NA 1032608N/AUnclassifiedbenzophenone2-mercapto pyridine2637-34-5NA 942671N/AUnclassified2-nitro-1-butyl phosphate57249-19-1569022033N/AUnclassified2-Nitropropane79-46-9#####3301ImpurityUnclassified3′,6′-Dihydro-2′,4′,5′,7′-15905-32-5#####NA 981DyeUnclassifiedtetraiodospiro(isobenzofuran-1(3H),9′-(9H)xanthen)-3-one4-hydroxydiphenylamine122-37-2NA 217NA 217BreakdownUnclassifiedproduct5-methyl-2-hexanone110-12-3NA 813230N/AUnclassifiedAcetaldehyde75-07-0#####3012N/AUnclassifiedAcetic anhydride108-24-7440073014N/AUnclassifiedAcetone67-64-144101747SolventUnclassifiedAcetonitrile75-05-8NA 6993015SolventUnclassifiedAcetophenone98-86-2#####2074N/AUnclassifiedAcid blue 182NA 599NA 1082353DyeUnclassifiedAcid blue 7NA 385NA 7022352DyeUnclassifiedAcid blue 9, diammonium salt2650-18-2#####2154Herbicide, DyeUnclassifiedAcid blue 9, disodium salt3844-45-9#####3562Herbicide, DyeUnclassifiedAcid yellow 231934-21-0#####2155Herbicide, DyeUnclassifiedAcridinic basesNA 1356NA 193NA 192RepellentUnclassifiedAcrylic acid79-10-7NA 1292118N/AUnclassifiedAD-67NA 1378NA 195NA 194HerbicideUnclassifiedSafenerAdjuvantsNA 1484NA 221NA 220AdjuvantUnclassifiedAgent 1059-106NA 388NA 7082357N/AUnclassifiedAgent 1059-108NA 600NA 1082358N/AUnclassifiedAgent 1315-33ANA 389NA 7093881N/AUnclassifiedAgent 1315-33NNA 390NA 7103879N/AUnclassifiedAgent 1594-9NA 654NA 1203880N/AUnclassifiedAgent 551-85NA 387NA 7072356N/AUnclassifiedAgent W-218NA 391NA 7112359N/AUnclassifiedAldehyde C10112-31-2#####NA 107N/AUnclassifiedAldehyde C11112-44-7#####NA 107N/AUnclassifiedAldehyde C12112-54-9#####NA 107N/AUnclassifiedAldehyde C666-25-1#####NA 107N/AUnclassifiedAldehyde C8124-13-0#####NA 107N/AUnclassifiedAldimorphNA 1340NA 188NA 187FungicideUnclassifiedAliphatic aminesNA 713NA 1302362N/AUnclassifiedAlkanol XCNA 828NA 1523931AdjuvantUnclassifiedAlkatronic PGP-33-4NA 395NA 7172363N/AUnclassifiedAlkyl (C9H12) benzenesNA 310NA 5892371SolventUnclassifiedAmine 22021652-27-7NA 1413033N/AUnclassifiedAmines, aliphaticNA 277NA 5431747N/AUnclassifiedAmino acidsNA 1359NA 193NA 192Plant GrowthUnclassifiedRegulatorAmmonium propionateNA 1061NA 1585015Microbiocide,UnclassifiedPreservativeAmsco-solvNA 271NA 5262386SolventUnclassifiedAmygdalinic acid diethylNA 1448NA 215NA 214InsectUnclassifiedamideRepellentAmyl acetate628-63-71691889N/AUnclassifiedAniline62-53-3#####3056N/AUnclassifiedAnionic wax emulsion61789-97-7NA 5153818N/AUnclassifiedAnionic wax emulsionNA 892NA 1713848N/AUnclassifiedAquashade92170-50-8#####NA 909Herbicide, DyeUnclassifiedArmul 1426NA 267NA 5223878N/AUnclassifiedArmul 1426 HFNA 822NA 1513877N/AUnclassifiedArmul 1427NA 268NA 5233883N/AUnclassifiedArmul 1427 HFNA 589NA 1063876N/AUnclassifiedArmul 214/215NA 265NA 5202391N/AUnclassifiedArmul 22NA 263NA 5182389N/AUnclassifiedArmul 33NA 587NA 1062390N/AUnclassifiedArmul 358NA 266NA 5212392N/AUnclassifiedArmul 646NA 588NA 1062393N/AUnclassifiedArmul 88NA 264NA 5193908N/AUnclassifiedArtificial peanut butter flavorNA 717NA 1312397N/AUnclassifiedwl-5344Astrazon yellow 4g200NA 258NA 5112399DyeUnclassifiedAtlox 1045A61723-83-9NA 1523911N/AUnclassifiedAtplus 300FNA 255NA 5073916N/AUnclassifiedb-Bromo-b-nitrostyrene7166-19-0NA 221NA 221MicrobiocideUnclassifiedBarochem B464NA 247NA 4992413N/AUnclassifiedBasic violet 18004-87-3395033584DyeUnclassifiedBCPNA 237NA 46564N/AUnclassifiedBe-4526 phthalo blue lake r-cNA 244NA 4883518DyeUnclassifiedBenfuresate68505-69-1NA 187NA 187HerbicideUnclassifiedBensultap17606-31-4NA 185NA 185InsecticideUnclassifiedBenzene sulfonyl chloride98-09-9NA 4892415N/AUnclassifiedBenzfendizone158755-95-4NA 230NA 230HerbicideUnclassifiedBenzobicyclon156963-66-5NA 230NA 230HerbicideUnclassifiedBenzofenap82692-44-2NA 211NA 211HerbicideUnclassifiedBenzophenone-2131-55-5NA 4923063N/AUnclassifiedBenzophenone-3119-61-93152417N/AUnclassifiedBenzyl chloride100-44-7NA 4862419N/AUnclassifiedBerol 927NA 894NA 1713874N/AUnclassifiedBerol 968NA 893NA 1713873N/AUnclassifiedBethoxazin163269-30-5NA 230NA 230HerbicideUnclassifiedBHA25013-16-5NA 4842420N/AUnclassifiedBicyclic and methene resinsNA 242NA 4853516N/AUnclassifiedBioban p-148737304-88-4#####1742MicrobiocideUnclassifiedBiphenyl92-52-417002227Microbiocide,UnclassifiedFungicideBisphenol A80-05-7NA 4823070N/AUnclassifiedBisphenol F205672NA 216NA 215N/AUnclassifiedBispyribac125401-75-4NA 203NA 203HerbicideUnclassifiedBisthiosemi39603-48-0NA 206NA 206RodenticideUnclassifiedBlock polymer ofNA 850NA 1585011N/AUnclassifiedcarbonyldiamidepolyoxyalkylated glycol adductBrandolNA 1379NA 195NA 194FungicideUnclassifiedBromoacetic acid79-08-38702NA 102N/AUnclassifiedBurgundy mixtureNA 1380NA 195NA 194FungicideUnclassifiedBusan 1009NA 1564NA 227NA 227FungicideUnclassifiedButadiene-acrylonitrile9003-18-3NA 4722432N/AUnclassifiedcopolymerButane106-97-8NA 4731562N/AUnclassifiedButhiobate51308-54-4NA 206NA 206FungicideUnclassifiedButyl mercaptan109-79-5#####5087Deer Repellent,UnclassifiedBear RepellentC-PA-1224 blackNA 191NA 3792483N/AUnclassifiedCalcium propionate4075-81-4777012441PreservativeUnclassifiedCambendichlor56141-00-5NA 230NA 230HerbicideUnclassifiedCapric acid334-48-5#####2315MicrobiocideUnclassifiedCaprylic acid124-07-2#####2316MicrobiocideUnclassifiedCaramel colorNA 720NA 1312444DyeUnclassifiedCarfentrazone128621-72-7NA 210NA 210HerbicideUnclassifiedCarfentrazone-ethyl128639-02-1#####5130HerbicideUnclassifiedCarpropamid104030-54-8NA 203NA 203FungicideUnclassifiedCartap15263-53-3NA 181NA 181InsecticideUnclassifiedCartap hydrochloride22042-59-7NA 182NA 181InsecticideUnclassified(unspecified hydrochloride)Cartap monohydrochloride15263-52-2NA 182NA 181InsecticideUnclassifiedCetiol HE66105-29-1#####NA 871InsecticideUnclassifiedCGA-154281NA 721NA 1322451N/AUnclassifiedChartersol-1NA 221NA 4282453SolventUnclassifiedChem-o-thane D-3860/D-3861NA 223NA 4302454N/AUnclassifiedChicago sludge68188-15-8NA 1473605N/AUnclassifiedChloracetic acid79-11-8#####3102N/AUnclassifiedChloral-bis-acylalNA 1344NA 191NA 191Plant GrowthUnclassifiedRegulatorChloral-semi-acetalNA 1345NA 191NA 191HerbicideUnclassifiedChloretazateNA 1403NA 197NA 196Plant GrowthUnclassifiedRegulatorChlorfenprop59404-06-7NA 181NA 180HerbicideUnclassifiedChlorfenprop-methyl14437-17-3#####NA 156HerbicideUnclassifiedChlorinated rubber2594016NA 4273606N/AUnclassifiedChlormethiuron28217-97-2NA 206NA 206InsecticideUnclassifiedChlorobenzene108-90-7565042460N/AUnclassifiedCholine chloride67-48-1NA 191NA 190RodenticideUnclassifiedCinidon-ethyl142891-20-1NA 216NA 215HerbicideUnclassifiedCitowettNA 218NA 4122471Soap/SurfactantUnclassifiedCloquintocet88349-88-6NA 219NA 218HerbicideUnclassifiedSafenerCloquintocet mexyl99607-70-2NA 191NA 190HerbicideUnclassifiedSafenerCloxyfonac32791-87-0NA 204NA 203Plant GrowthUnclassifiedRegulatorColgate crystal white handNA 202NA 3932476N/AUnclassifieddishwashing liquidCollagenNA 203NA 3941805N/AUnclassifiedColloid 643NA 582NA 1052477N/AUnclassifiedColloid 840NA 791NA 1463527N/AUnclassifiedCookiesNA 641NA 1173621BaitUnclassifiedCredazine14491-59-9NA 207NA 206HerbicideUnclassifiedCubietNA 1367NA 193NA 193Fungicide,UnclassifiedPruning AidCyclohexanone108-94-125902177SolventUnclassifiedCyclopentadiene polymerNA 1450NA 215NA 214InsecticideUnclassifiedCymiazol hydrochloride61676-87-7NA 215NA 214InsecticideUnclassifiedCymoxanil57966-95-7#####4002FungicideUnclassifiedCyometrinil63278-33-1NA 207NA 206HerbicideUnclassifiedSafenerCysteine52-90-4NA 190NA 190Plant GrowthUnclassifiedRegulatorD & C red no. 2818472-87-2#####3515DyeUnclassifiedD & C red no. 371632455NA 1173634DyeUnclassifiedD & C yellow 10 lake68814-04-0NA 3652487DyeUnclassifiedD & C yellow no. 8NA 829NA 1523991DyeUnclassifiedD-425NA 184NA 3672489N/AUnclassifiedD-79 solventNA 183NA 3662488SolventUnclassifiedDaxad 23NA 185NA 3682491N/AUnclassifiedDay-glo saturn yellow AX-17-NNA 186NA 3692492DyeUnclassifiedDE-570NA 1459NA 216NA 216N/AUnclassifiedDelvet 65NA 177NA 3572494N/AUnclassifiedDesoto urethane resinNA 179NA 3592497N/AUnclassifiedDevice (swimming poolNA 1503NA 222NA 222Algaecide,Unclassifiedalgaecide, bacteriacide,Microbiocide,molluscicide) no guaranteeMollusciciderequiredDevice, no guarantee requiredNA 1502NA 222NA 221N/AUnclassifiedDi-1-p-mentheneNA 1381NA 195NA 194Plant GrowthUnclassifiedRegulatorDiafenthiuron80060-09-9NA 186NA 185InsecticideUnclassifiedDichloro acetic acid79-43-6NA 1053133N/AUnclassifiedDichlorovinyl acidNA 174NA 3472502BreakdownUnclassifiedproductDiclobutrazol75736-33-3NA 186NA 185FungicideUnclassifiedDiclomezine62865-36-5NA 204NA 204FungicideUnclassifiedDicyclanil112636-83-6NA 211NA 211Insect GrowthUnclassifiedRegulatorDicyclopentadiene77-73-6NA 186NA 185Plant GrowthUnclassifiedRegulator, Dogand CatRepellentDicyclopentadiene linseed oil68213-53-631612NA 291N/AUnclassifiedcopolymerDiethyl phosphate598-02-7NA 180NA 179BreakdownUnclassifiedproductDiethyl sulfide352-93-2#####5088Bear RepellentUnclassifiedDiethyldithio phosphate298-06-6NA 180NA 179BreakdownUnclassifiedproductDiethylthio phosphate5871-17-0NA 180NA 179BreakdownUnclassifiedproductDiisoamyl ketone2050-99-9NA 3253155SolventUnclassifiedDiisobutyl ketone108-83-8441071946SolventUnclassifiedDikegulac18467-77-1NA 181NA 180HerbicideUnclassifiedDikegulac sodium52508-35-7#####2004Plant GrowthUnclassifiedRegulatorDimer acid6144-28-1NA 3303158N/AUnclassifiedDimethyl phosphate813-78-5NA 180NA 179BreakdownUnclassifiedproductDimethyl sulfoxide67-68-51773169SolventUnclassifiedDimethyldithio phosphate756-80-9NA 180NA 180BreakdownUnclassifiedproductDimethylthio phosphateNA 1339NA 180NA 179BreakdownUnclassifiedproductDioxane123-91-1NA 3002529Solvent,UnclassifiedImpurityDiphenyl methane101-81-5NA 3013171N/AUnclassifiedDiphenylamine122-39-438501228Fungicide,UnclassifiedPlant GrowthRegulator,InsecticideDipropyl isocinchomerate3737-22-2NA 204NA 204InsectUnclassifiedRepellentDipropyl isocinchomeronate136-45-847201681InsectUnclassifiedRepellentDog or cat collarsNA 155NA 2913645N/AUnclassifiedDow Corning FG-10NA 147NA 2812541N/AUnclassifiedDowanol desg solventNA 725NA 1332538SolventUnclassifiedDrewplus L-768NA 148NA 2832542N/AUnclassifiedDyestuffsNA 689NA 1271913DyeUnclassifiedEmcol AL69-49NA 726NA 1332544N/AUnclassifiedEmphos CS-121NA 727NA 1332545Soap/SurfactantUnclassifiedEmulgatorNA 143NA 2772546N/AUnclassifiedEmulsogen CP 136NA 576NA 1042547AdjuvantUnclassifiedEmulsogen NP 11-300NA 144NA 2782548AdjuvantUnclassifiedEndothall145-73-3389015813Herbicide,UnclassifiedDefoliantEndothall, di (N,N-NA 949NA 2711355Herbicide,Unclassifieddiethylalkylamine) saltDefoliantEndothall, di (N,N-66330-88-9389051904Herbicide,Unclassifieddimethylalkylamine) saltDefoliantEndothall, di(N,N-2536-26-738902NA 323Herbicide,Unclassifieddimethyltridecylamine) saltDefoliantEndothall, diammonium salt17439-94-038908NA 326Herbicide,UnclassifiedDefoliantEndothall, dipotassium salt2164-07-0389041356Herbicide,UnclassifiedDefoliantEndothall, disodium salt129-67-938903260Herbicide,UnclassifiedDefoliantEndothall, mono (N,N-diethylNA 926NA 41354Herbicide,Unclassifiedalkylamine) saltDefoliantEndothall, mono [N,N-NA 929NA 612056Herbicide,Unclassifieddimethyl alkylamine] saltDefoliantEndothall, mono(N,N-2536-27-838906NA 325Herbicide,Unclassifieddimethyltridecylamine) saltDefoliantEndothall, N,N-NA 128238907NA 174Herbicide,Unclassifieddimethylcocamine salt (1:2)AlgaecideEpoxidized linseed oil2232670NA 2722550Insecticide,UnclassifiedAdjuvantEpoxy resinsNA 139NA 2693650N/AUnclassifiedErythrosine B16423-68-0#####2224Dye,UnclassifiedInsecticideEscorez 11029048-47-9NA 1463546N/AUnclassifiedEspesol INA 140NA 2702552SolventUnclassifiedEtacelasil37894-46-5NA 188NA 187Defoliant, PlantUnclassifiedGrowthRegulatorEthanethiol75-08-1NA 187NA 186RodenticideUnclassifiedEthomeenNA 136NA 2652553N/AUnclassifiedEthyl acrylate140-88-5NA 2592117N/AUnclassifiedEthyl formate109-94-443102278Fumigant,UnclassifiedInsecticideEthyl methacrylate97-63-2NA 2483203N/AUnclassifiedEthylene-acrylic acid9010-77-9NA 2533653AdjuvantUnclassifiedcopolymerEthylene-acrylic terpolymerNA 133NA 2541950AdjuvantUnclassifiedEthylhexanoate123-66-0NA 190NA 190Fungicide,UnclassifiedMicrobiocideExtenderNA 1377NA 195NA 194SynergistUnclassifiedFatty alcoholsNA 1364NA 193NA 192Plant GrowthUnclassifiedRegulator,AdjuvantFD&C blue no. 1 aluminum53026-57-6NA 2423000DyeUnclassifiedlakeFD&C green no. 3NA 127NA 2432566DyeUnclassifiedFD&C red no. 40NA 947#####2567Dye, ImpurityUnclassifiedFeed supplementsNA 128NA 2443655N/AUnclassifiedFenchlorazole103112-35-2NA 181NA 181HerbicideUnclassifiedSafenerFenchlorim3740-92-9NA 182NA 181HerbicideUnclassifiedSafenerFenitropan65934-95-4NA 207NA 207FungicideUnclassifiedFenpiclonil74738-17-3NA 188NA 187FungicideUnclassifiedFenpropidin67306-00-7NA 184NA 183FungicideUnclassifiedFenpropimorph67306-03-0#####NA 988FungicideUnclassifiedFenpropimorph67564-91-4NA 201NA 200FungicideUnclassifiedFenthiosulfNA 1406NA 198NA 197InsecticideUnclassifiedFertilizer, generalNA 729NA 1332569N/AUnclassifiedFilter paper e-d-601-25NA 122NA 2353525N/AUnclassifiedFlomo 1212NA 124NA 2392572Soap/SurfactantUnclassifiedFlomo 4NPNA 616NA 1122573Soap/SurfactantUnclassifiedFlorasulamNA 1447NA 214NA 214HerbicideUnclassifiedFlubenzimine (unstated37893-02-0NA 188NA 187InsecticideUnclassifiedstereochemistry)Flumequine42835-25-6NA 188NA 187MicrobiocideUnclassifiedFlumiclorac87547-04-4NA 232NA 232HerbicideUnclassifiedFlumipropyn84478-52-4NA 229NA 229HerbicideUnclassifiedFlupropanate756-09-2NA 204NA 204HerbicideUnclassifiedFlupropanate, sodium salt22898-01-7NA 211NA 211HerbicideUnclassifiedFlurazole72850-64-7NA 187NA 186HerbicideUnclassifiedSafenerFlurtamone96525-23-4NA 217NA 216HerbicideUnclassifiedFluthiacet149253-65-6NA 205NA 204HerbicideUnclassifiedFluxofenim88485-37-4NA 202NA 201HerbicideUnclassifiedSafenerFormaldehyde50-00-043001295Microbiocide,UnclassifiedFungicideFosetyl-A139148-24-8#####2210FungicideUnclassifiedFragrance 1256 HNA 115NA 2272575FragranceUnclassifiedFragrance for mosquito51843NA 1403007FragranceUnclassifiedrepellent p-7510Fragrance N-5716NA 116NA 2283852FragranceUnclassifiedFragrance orange 418228NA 117NA 2293889FragranceUnclassifiedFragrance PNLF 6986NA 633NA 1163563FragranceUnclassifiedFragrance RS-2661NA 824NA 1513891FragranceUnclassifiedFrambinone5471-51-2NA 212NA 212FragranceUnclassifiedFumaric acid110-17-851201297N/AUnclassifiedFumaric and crotonic acids,NA 118NA 2301711N/AUnclassifiedesters ofFumigantsNA 1492NA 221NA 221FumigantUnclassifiedFuraneol 15% p.g.NA 119NA 2312576N/AUnclassifiedFurfural98-01-1433011522N/AUnclassifiedGentian97676-22-7#####NA 108DyeUnclassifiedGentian violet548-62-9395021270Microbiocide,UnclassifiedDyeGentian violet548-62-998401NA 173Microbiocide,UnclassifiedDyeGivaudan muquet PA-6664NA 575NA 1042580N/AUnclassifiedGlidden no. 3200 white latexNA 113NA 2242581N/AUnclassifiedGlueNA 643NA 1183661N/AUnclassifiedGlufosinate51276-47-2NA 203NA 202HerbicideUnclassifiedGlufosinate-ammonium77182-82-2#####3946HerbicideUnclassifiedGrease (bands, fruit frees)NA 1350NA 192NA 191InsecticideUnclassifiedGreen M liquid dyeNA 106NA 2113840DyeUnclassifiedHeptopargil73886-28-9NA 208NA 207Plant GrowthUnclassifiedRegulatorHeptyl butyrate5870-93-9NA 2073668N/AUnclassifiedHi-sol 15NA 97NA 1922594SolventUnclassifiedHostaphat MDAR-N-040NA 98NA 1932596N/AUnclassifiedHostapon T powder highly97-80-3NA 1713942N/AUnclassifiedconcentratedHydrazine302-01-2NA 1952598Impurity,UnclassifiedBreakdownproductHydrolysed linseed fatty acidNA 1436NA 212NA 212N/AUnclassifiedHydroxyl amine sulfate10039-54-0NA 1813235N/AUnclassifiedHydroxyphenyl-salicylamideNA 1396NA 197NA 196FungicideUnclassifiedInabenfide82211-24-3NA 205NA 204Plant GrowthUnclassifiedRegulatorIndanofan133220-30-1NA 232NA 232HerbicideUnclassifiedIndigo carmine860-22-0NA 1463530DyeUnclassifiedInert (VOC reevaluation)NA 877NA 1693973N/AUnclassifiedInert ingredientsNA 872NA 1600N/AUnclassifiedInstex 10100 color concentrateNA 88NA 1702615DyeUnclassified(black)Irganox 10106683-19-8NA 1733623N/AUnclassifiedIrganox 10106683-19-8NA 1703523N/AUnclassifiedIrganox 10762082-79-3NA 1742617N/AUnclassifiedIso-amyl mercaptan541-31-1NA 213NA 212N/AUnclassifiedIsobutyl acetate110-19-0NA 1433241N/AUnclassifiedIsobutyric acid79-31-2#####2110PreservativeUnclassifiedIsooctyl phosphate12645-53-3NA 1623258Soap/Surfactant,UnclassifiedAdjuvantIsopropanolamine nitriteNA 87NA 1663245N/AUnclassifiedIsopropylamine75-31-0NA 1573246N/AUnclassifiedIsoprothiolane50512-35-1NA 189NA 188FungicideUnclassifiedIsovalNA 1385NA 195NA 195RodenticideUnclassifiedIsoxapyrifop87757-18-4NA 208NA 208HerbicideUnclassifiedIvory snowNA 75NA 1463674N/AUnclassifiedK 1A112NA 77NA 1482628N/AUnclassifiedKelsol 513468309-52-4NA 1493526SolventUnclassifiedKetoconazole65277-42-1NA 216NA 215FungicideUnclassifiedKorax2425-66-311302351N/AUnclassifiedKrynac 1122NA 79NA 1512632N/AUnclassifiedLatex paintNA 74NA 1442634N/AUnclassifiedLeonil DB powderNA 71NA 1392639N/AUnclassifiedLignoflexNA 68NA 1313265N/AUnclassifiedLimonia 19-11189NA 69NA 1322643N/AUnclassifiedLinseed-soya alkyd resinNA 62NA 1172646N/AUnclassifiedLithium29457-72-5750045678Insecticide,Unclassified(perfluorooctane)sulfonateAdjuvantLong oil alkyd 5070NA 64NA 1202648InsecticideUnclassifiedLubrizol 544NA 65NA 1212649Solvent,UnclassifiedAdjuvantLuna yellow NB-1 1270NA 66NA 1222651DyeUnclassifiedLuviset cap25035-26-1NA 1233867N/AUnclassifiedMacroplast UK 8202/UK 5400NA 57NA 1082652N/AUnclassifiedMacroplast VAX-11688/UKNA 58NA 1092653N/AUnclassified5400Malachite green569-64-239504366DyeUnclassifiedMaleic anhydride108-31-6NA 1023272N/AUnclassifiedMaleic anhydride, polymer37199-81-8NA 1033271N/AUnclassifiedwith 2,4,4-trimethyl pentane,sodium saltMaleic hydrazide123-33-151501368Plant GrowthUnclassifiedRegulatorMaleic hydrazide10071-13-3NA 210NA 209Plant GrowthUnclassifiedRegulatorMaleic hydrazide, choline salt71203-19-551504NA 422Plant GrowthUnclassifiedRegulatorMaleic hydrazide,5716-15-451502778Plant GrowthUnclassifieddiethanolamine saltRegulatorMaleic hydrazide, potassium28382-15-2515032130Plant GrowthUnclassifiedRegulator,HerbicideMalic acid6915-15-7511011364MicrobiocideUnclassifiedMark 1500NA 49NA 962663N/AUnclassifiedMark 1600NA 50NA 972664N/AUnclassifiedMark 1601NA 51NA 982665N/AUnclassifiedMark 1603NA 740NA 1352666N/AUnclassifiedMark 1607NA 569NA 1032667N/AUnclassifiedMark 495NA 56NA 1072660N/AUnclassifiedMark 565ANA 48NA 952661N/AUnclassifiedMark 706NA 739NA 1352662N/AUnclassifiedMarter white 400NA 52NA 992668N/AUnclassifiedMedicated blockNA 47NA 923684N/AUnclassifiedMefenpyr135591-00-3NA 182NA 181HerbicideUnclassifiedSafenerMefenpyr-diethyl135590-91-9R47618NA 177HerbicideUnclassifiedSafenerMenhaden oil8002-50-4NA 933686N/AUnclassifiedMenthol1490-04-6516011074Dog and CatUnclassifiedRepellentMethoxy-2,4-dihydroxyNA 46NA 893281N/AUnclassifiedpenteneMethoxyphenone41295-28-7NA 209NA 208HerbicideUnclassifiedMethyl esters of cottonseed oil61788-60-1NA 1483687AdjuvantUnclassifiedMethyl ethyl ketone78-93-3441032680SolventUnclassifiedMethyl formate107-31-353701391FumigantUnclassifiedMethyl hydrogenated rosinate8050-15-5NA 823688N/AUnclassifiedMethyl isocyanate624-83-9NA 180NA 180BreakdownUnclassifiedproductMethyl isothiocyanate556-61-668103392Fumigant,UnclassifiedInsecticide,Herbicide,Nematicide,BreakdownproductMethyl methacrylate80-62-6NA 782151N/AUnclassifiedMethylene blue61-73-439505387Fungicide, DyeUnclassifiedMetosulam139528-85-1NA 184NA 184HerbicideUnclassifiedMilorganite68512-89-0NA 663693N/AUnclassifiedMKH 6561NA 1466NA 217NA 216HerbicideUnclassifiedMON 466071526-07-3#####NA 162N/AUnclassifiedMonosodium glutamate32221-81-1NA 592691N/AUnclassifiedMorwet EFWNA 36NA 602693AdjuvantUnclassifiedMorwet IPNA 568NA 1023694AdjuvantUnclassifiedMorwet IPNA 887NA 1702694AdjuvantUnclassifiedMultiresidue carbamate screenNA 848NA 1584042N/AUnclassifiedMultiresidue chlorinatedNA 847NA 1584043N/AUnclassifiedhydrocarbon screenMultiresidue organophosphateNA 846NA 1584044N/AUnclassifiedscreenMultiresidue triazine screenNA 845NA 1574045N/AUnclassifiedN,N-Diallyl-2,2-37764-25-3NA 187NA 186HerbicideUnclassifieddichloroacetamideSafenern-Butyl acetate142-62-1#####2434N/AUnclassifiedN-methyl-2-pyrrolidone237900NA 762684N/AUnclassifiedN-TDFNA 22NA 342713N/AUnclassifiedNaphthalene-formaldehyde9008-63-3NA 582692Insecticide,Unclassifiedcondensate sulfonic acid,Fungicide,metallic saltsMicrobiocide,AdjuvantNaphthalic anhydride81-84-5NA 209NA 208HerbicideUnclassifiedSafenerNeo-decanoic acid26896-20-8975012699N/AUnclassifiedNeodol 2563393-82-8NA 513930N/AUnclassifiedNeuessence powder 411669NA 781NA 1403003N/AUnclassifiedNipyraclofen99662-11-0NA 229NA 229HerbicideUnclassifiedNitrile rubberNA 743NA 1352704N/AUnclassifiedNitro ethane79-24-3NA 493298SolventUnclassifiedNitromethane75-52-5NA 423299SolventUnclassifiedNitrothal-isopropyl10552-74-6NA 181NA 180FungicideUnclassifiedNon-ionic surfactantsNA 1443NA 214NA 213Soap/Surfactant,UnclassifiedAdjuvantNonoxynol-9-phosphateNA 29NA 432706AdjuvantUnclassifiedNorbormide991-42-4862012711N/AUnclassifiedNuostabe v-1913NA 23NA 352715N/AUnclassifiedNuxtra calcium 6% catalystNA 25NA 372716N/AUnclassifiedNuxtra calcium 8% catalystNA 26NA 382717N/AUnclassifiedNuxtra manganese 9% catalystNA 15NA 242718N/AUnclassifiedNylon32131-17-2NA 253703N/AUnclassifiedOctachlorostyrene29082-74-4NA 215NA 215N/AUnclassifiedOrvus ES paste concentrateNA 3NA 32726N/AUnclassifiedOvex80-33-120201452Insect GrowthUnclassifiedRegulatorOxabetrinil74782-23-3NA 205NA 204HerbicideUnclassifiedSafenerOxadiargyl39807-15-3NA 211NA 211HerbicideUnclassifiedOxapyrazon4489-31-0NA 209NA 208HerbicideUnclassifiedOxapyrazon sodium25316-56-7NA 217NA 217HerbicideUnclassifiedOxaziclomefone153197-14-9NA 233NA 233HerbicideUnclassifiedOxidized polyethylene68441-17-8NA 1183713N/AUnclassifiedOxygenated solventsNA 379NA 6871767SolventUnclassifiedp-Chloronitrobenzene100-00-5NA 183NA 182InsecticideUnclassifiedPaintNA 380NA 6883715N/AUnclassifiedPanasol AN-2NA 381NA 6902733SolventUnclassifiedPanasol AN-3NA 382NA 6912732SolventUnclassifiedParaformaldehyde30525-89-443002456Microbiocide,UnclassifiedFungicide,InsecticidePareth 91-8NA 889NA 1702734N/AUnclassifiedPentoxazone110956-75-7NA 233NA 233HerbicideUnclassifiedPerfluorooctane sulfonateNA 1456NA 216NA 215InsecticideUnclassifiedPerfume 08-28NA 750NA 1362740FragranceUnclassifiedPerfume bouquet no. 3NA 366NA 6722741FragranceUnclassifiedPerfume, chem-mask C no. 280NA 367NA 6732742FragranceUnclassifiedPerfume, colonial bouquetNA 368NA 6742744FragranceUnclassified8095Perfume, compound 2-2723NA 752NA 1362745FragranceUnclassifiedPerfume, compound 44.368/gNA 370NA 6762747FragranceUnclassifiedPerfume, compound bouquetNA 369NA 6752746FragranceUnclassifiedECPerfume, DL 10613NA 823NA 1513888FragranceUnclassifiedPerfume, eaudesol malNA 371NA 6772748FragranceUnclassified(special)Perfume, fragrance oil 6198NA 372NA 6782750FragranceUnclassifiedAGPerfume, fresh meadows #651NA 753NA 1362751FragranceUnclassifiedPerfume, herbal fragrance oilNA 354NA 6572753FragranceUnclassifiedno. 062Perfume, malamasque no. 59NA 355NA 6582754FragranceUnclassifiedPerfume, malathion 21-639NA 356NA 6592755FragranceUnclassifiedPerfume, marbelle 72160ANA 357NA 6602756FragranceUnclassifiedPerfume, mimosa no. 5NA 754NA 1362757FragranceUnclassifiedPerfume, neutroleum alphaNA 358NA 6612758FragranceUnclassifiedPerfume, new mown hayNA 359NA 6622759FragranceUnclassifiedPerfume, norda EC-137NA 360NA 6632760FragranceUnclassifiedPerfume, pet perfume # 27253NA 361NA 6642761FragranceUnclassifiedPerfume, phase b-5NA 755NA 1362762FragranceUnclassifiedPerfume, R-7402NA 362NA 6652763FragranceUnclassifiedPerfume, veilex 40019NA 363NA 6662764FragranceUnclassifiedPerfume, washroom cleanerNA 364NA 6672765FragranceUnclassifiedbouquet # 152-587Phenyl ether101-84-8NA 6533324N/AUnclassifiedPhosametineNA 1400NA 197NA 196HerbicideUnclassifiedPhosdiphen36519-00-3NA 209NA 209FungicideUnclassifiedPhosphoproteinsNA 350NA 6461250N/AUnclassifiedPhthalaldehyde643-79-8#####5107MicrobiocideUnclassifiedPhthalide27355-22-2NA 205NA 205FungicideUnclassifiedPhthalo greenNA 348NA 6422779DyeUnclassifiedPicaridinNA 1434NA 212NA 211InsectUnclassifiedRepellentPigment blue 2957455-37-5NA 6432780DyeUnclassifiedPigment green 71328-53-6NA 6363870DyeUnclassifiedPigment red 1783049-71-6NA 6373869DyeUnclassifiedPigment red 57:16887-51-9NA 1713868DyeUnclassifiedPigment red no. 4816013-44-8NA 1493729DyeUnclassifiedPimaricin7681-93-8NA 203NA 202FungicideUnclassifiedPiperalin3478-94-297003488FungicideUnclassifiedPiperine94-62-2NA 223NA 223N/AUnclassifiedPiproctanyl69309-47-3NA 209NA 209Plant GrowthUnclassifiedRegulatorPiproctanyl bromide56717-11-4NA 218NA 217Plant GrowthUnclassifiedRegulatorPlastic polymersNA 339NA 625764AdjuvantUnclassifiedPlurafac B-2669227-21-0NA 6262782N/AUnclassifiedPlurafac C-1769227-21-0NA 1372783N/AUnclassifiedPluraflo E4ANA 340NA 6272784Soap/SurfactantUnclassifiedPluronic 10-R-5NA 345NA 6322790N/AUnclassifiedPluronic 1-101NA 759NA 1372788N/AUnclassifiedPluronic L-62 LFNA 342NA 6292786N/AUnclassifiedPluronic L61NA 341NA 6282785N/AUnclassifiedPluronic 163NA 343NA 6302787N/AUnclassifiedPluronic P-104NA 344NA 6312789N/AUnclassifiedPMS-5406-T pigmentNA 346NA 6332791N/AUnclassifiedPo-san37339-61-098804NA 861N/AUnclassifiedPo-san76930-44-498804NA 862N/AUnclassifiedPoly(oxyethylene)31512-74-0691831576MicrobiocideUnclassified(dimethylimino) ethylene(dimethylimino) ethylenedichloridePoly-i-para-menthene34363-01-4NA 6101314Insect GrowthUnclassifiedRegulatorPolyacrylamide polymer2592984NA 6342111AdjuvantUnclassifiedPolyalkylene etherNA 347NA 6352271AdjuvantUnclassifiedPolyamide resinNA 621NA 1122795N/AUnclassifiedPolyamine polymerNA 334NA 6201907AdjuvantUnclassifiedPolyhexamethylene32289-58-0#####2258Microbiocide,UnclassifiedbiguanidineFungicidePolymer emulsion KNA 329NA 6112804AdjuvantUnclassifiedPolymerized acrylic acid2592860529023738AdjuvantUnclassifiedPolyoxin11113-80-7NA 194NA 193FungicideUnclassifiedPolyurethaneNA 426NA 7683770N/AUnclassifiedPolyvinyl butyral resinNA 427NA 7692820N/AUnclassifiedPolyvinyl chloride9002-86-2NA 7702821N/AUnclassifiedPolyvinylpyrrolidone-82010-83-143003NA 367MicrobiocideUnclassifiedformaldehyde complexPolyvis O-SHNA 428NA 7712823N/AUnclassifiedPoly[hydroxyethylene(dimethyliminio)NA 1512NA 223NA 222MicrobiocideUnclassifiedethylene(dimethylimino)methylene dichloride]Potassium 3-(2-(2-((2-(2-NA 998NA 7793352PreservativeUnclassifiedhydroxy ethyl) ethyl) octadecylamino)ethoxy) propionatePotassium N-ethyl perfluoroNA 997NA 7773354Insecticide,Unclassifiedoctane sulfonamide acetateAdjuvantProbenazole27605-76-1NA 205NA 205Fungicide,UnclassifiedMicrobiocidePropellant A-46NA 441NA 7942834PropellantUnclassifiedPropellant A-70NA 762NA 1372835PropellantUnclassifiedPropellant A-91NA 442NA 7952836PropellantUnclassifiedPropellant B-46NA 443NA 7963887PropellantUnclassifiedPropidineNA 1449NA 215NA 214InsectUnclassifiedRepellentPropionic acid79-09-477702505Fungicide,UnclassifiedMicrobiocide,PreservativePropyl-3-t-butylphenoxyacetateNA 1407NA 198NA 197Plant GrowthUnclassifiedRegulatorPyrazolynate58011-68-0NA 205NA 205HerbicideUnclassifiedPyribenzoxim168088-61-7NA 233NA 233HerbicideUnclassifiedPyriminobac136191-56-5NA 206NA 205HerbicideUnclassifiedPyroquilone57369-32-1NA 190NA 189FungicideUnclassifiedQuinacetol sulfate57130-91-3NA 210NA 209FungicideUnclassifiedQuinizarin green SS128-80-3NA 1093374DyeUnclassifiedQuinoclamine2797-51-5NA 185NA 184Herbicide,UnclassifiedAlgaecideQuinoxyfen124495-18-7NA 206NA 205FungicideUnclassifiedResins and polymersNA 1374NA 194NA 193Pruning Aid,UnclassifiedAdjuvantRH - 2485NA 1467NA 217NA 217InsecticideUnclassifiedRhodamine B81-88-9NA 1382846DyeUnclassifiedSebacic acid111-20-6NA 187NA 186RepellentUnclassifiedSec-butylamine13952-84-642141704FungicideUnclassifiedSeconal76-73-3NA 190NA 189N/AUnclassifiedSecret formula no. 1NA 2NA 21837N/AUnclassified,UnclassifiedSecret formula no. 2NA 458NA 8201838N/AUnclassifiedSilthiofam175217-20-6NA 210NA 210FungicideUnclassifiedSintofen130561-48-7NA 185NA 184Plant GrowthUnclassifiedRegulatorSodium 2-ethylhexanoate19766-89-3NA 214NA 214Fungicide,UnclassifiedMicrobiocideSodium caprylate29372790633388N/AUnclassifiedSodium chloroacetate3926-62-3#####NA 141HerbicideUnclassifiedSodium diacetoneketogulonateNA 1397NA 197NA 196Plant GrowthUnclassifiedRegulatorSodium gluconate527-07-11053406N/AUnclassifiedSodium methyl sulfate512-42-5NA 1453417N/AUnclassifiedSodium petroleum sulfonate68608-26-4790353431Insecticide,UnclassifiedAdjuvantSodium propionate137-40-6777033434Fungicide,UnclassifiedPreservativeSolulan 98NA 474NA 8742867SolventUnclassifiedSolulan L-575NA 763NA 1382868N/AUnclassifiedSolvent red 49509-34-2NA 8753900DyeUnclassifiedSpiroxamine118134-30-8NA 202NA 202FungicideUnclassifiedSponto 168NA 484NA 8882875N/AUnclassifiedSponto 232TNA 492NA 8962885N/AUnclassifiedSponto 234TNA 766NA 1382886N/AUnclassifiedSponto AK-30-02BTNA 485NA 8892876N/AUnclassifiedSponto AK31-27ANA 764NA 1382877N/AUnclassifiedSponto AK31-27BNA 486NA 8902878N/AUnclassifiedSponto AK31-38NA 487NA 8912879N/AUnclassifiedSponto AK31-56ANA 488NA 8922880N/AUnclassifiedSponto AK31-56BNA 765NA 1382881N/AUnclassifiedSponto AK31-56MNA 632NA 1163558N/AUnclassifiedSponto N-140BNA 489NA 8932882N/AUnclassifiedSponto N-300BNA 490NA 8942883N/AUnclassifiedSponto N-500BNA 491NA 8952884N/AUnclassifiedSta-pro 3000NA 493NA 8972889N/AUnclassifiedStepan C-65 methyl esterNA 496NA 9032893N/AUnclassifiedStepantan ANA 497NA 9042894N/AUnclassifiedStepfac 8172NA 767NA 1382895N/AUnclassifiedSterilixNA 656NA 121550MicrobiocideUnclassifiedSterox NJNA 498NA 9052896N/AUnclassifiedStoddard solvent8052-41-363504NA 516Solvent,UnclassifiedHerbicide,InsecticideStyrene acrylic copolymer25085-34-1NA 9073457AdjuvantUnclassifiedStyrene/pvp copolymer25086-29-7NA 9083812AdjuvantUnclassifiedSudan III85-86-9NA 9093459DyeUnclassifiedSulcotrione99105-77-8NA 185NA 184HerbicideUnclassifiedSulfated dipentaneNA 500NA 9113460N/AUnclassifiedSulfonated cod liver oilNA 1464NA 217NA 216N/AUnclassifiedSulglycapin51068-60-1NA 233NA 233HerbicideUnclassifiedSure sol 180NA 505NA 9162903SolventUnclassifiedSurflo B11NA 606NA 1102904Soap/SurfactantUnclassifiedSurflo B13NA 506NA 9172905Soap/SurfactantUnclassifiedSurflo B16NA 507NA 9182906Soap/SurfactantUnclassifiedSurflo B17NA 508NA 9192907Soap/SurfactantUnclassifiedSurflo B19NA 770NA 1392908Soap/SurfactantUnclassifiedSustane 3NA 622NA 1132909N/AUnclassifiedT-DETN-9.5NA 513NA 9282917N/AUnclassifiedT-mulz 565NA 528NA 9552944AdjuvantUnclassifiedT-mulz 94WNA 531NA 9582949AdjuvantUnclassifiedT-mulz AO2NA 772NA 1392943N/AUnclassifiedT-mulz ONA 529NA 9562945AdjuvantUnclassifiedT-mulz PBNA 530NA 9572946AdjuvantUnclassifiedT-Mulz VONA 610NA 1112947N/AUnclassifiedT-mulz WNA 773NA 1392948N/AUnclassifiedTabu powderNA 510NA 9221462N/AUnclassifiedTacksNA 818NA 1513816N/AUnclassifiedTenneco 225F PVC resinNA 514NA 9302919N/AUnclassifiedTenneco T500-100NA 771NA 1392920N/AUnclassifiedTenox 2NA 515NA 9312921PreservativeUnclassifiedTenox 4NA 516NA 9322922PreservativeUnclassifiedTenox RNA 517NA 9332923PreservativeUnclassifiedTenox S-1NA 518NA 9342924PreservativeUnclassifiedTensiofix B7416NA 895NA 1713943Soap/SurfactantUnclassifiedTensiofix B7453NA 896NA 1713944Soap/SurfactantUnclassifiedTergitol 15-S-12NA 623NA 1132926N/AUnclassifiedTergitol 15-S-12 acrylateNA 519NA 9352927N/AUnclassifiedTergitol 15-S-20NA 520NA 9362928N/AUnclassifiedtert-Butylamine Endothall26648-01-138909NA 327Herbicide,UnclassifiedDefoliantTetrahydrofuran109-99-9NA 9442933SolventUnclassifiedTexaphor specialNA 524NA 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*N/A = Not Available\


II. Augmenting the Sensitivity of Plants to Herbicides

In certain embodiments of the invention, the effectiveness of herbicides is augmented by methods and compositions for the contemporaneous administration of one or more ectophosphatase inhibitors in combination with herbicides. Such applications may, in addition to increasing the effectiveness of herbicides, allow the use of reduced concentrations of herbicides, thereby providing cost and environmental benefits.


Specifically contemplated by the invention are compositions comprising one or more ectophosphatase inhibitor(s) in combination with one or more herbicide(s) listed in Table 1. In one embodiment of the invention, the ectophosphatase inhibitor may or may not be a compound selected from formula I-XX. The herbicidal compositions or other compositions formulated for agricultural use, including compositions comprising insecticides and growth regulators, may be used with potentially any plant. The term “plant,” as used herein, refers to any type of plant. The inventors have provided below an exemplary description of some plants that may be used with the invention. However, the list is provided for illustrative purposes only and is not limiting, as other types of plants will be known to those of skill in the art and could be used with the invention.


Non-limiting examples of plant genera that may be treated in accordance with the invention include: Abutilon, Amaranthus, Artemisia, Asclepias, Avena, Axonopus, Borreria, Brachiaria, Brassica, Bromus, Chenopodium, Cirsium, Commelina, Convolvulus, Cynodon, Cyperus, Digitaria, Echinochloa, Eleusine, Elymus, Equisetum, Erodium, Helianthus, Imperata, Ipomoea, Kochia, Lolium, Malva, Oryza, Ottochloa, Panicum, Paspalum, Phalaris, Phragmites, Polygonum, Portulaca, Pteridium, Pueraria, Rubus, Salsola, Setaria, Sida, Sinapis, Sorghum, Triticum, Typha, Ulex, Xanthium, and Zea. Non-limiting common types of plants that may be controlled in accordance with the invention include varieties of grasses, broad leafs, succulents, trees and shrubs, barley, black nightshade, broadleaf signal grass, burcumber, chickweed, common ragweed, crabgrass, field pennycress, rough fleabane, foxtail, giant ragweed, goose grass, groundcherry, hemp sesbarria, henbit, jungle rice, kochia, lambs quarters, morning-glory spp., mustard, fall and Texas panicum, palma amaranth, prickly sida (teaweed), red rice, rye, seedling shattercone, shepherd's purse, sicklepod, sprangletop, sunflower, velvet leaf, volunteer corn, common and tall waterhemp, wheat, wild proso millet, witchgrass, wolly cupgrass; and common perennial weeds including Canada thistle, common milkweed, field bindweed, hemp dogbane, red vine, rhizone johnson grass, tall fescue, trumpet creeper, swamp smartweed and wisteria mukly. Star Thistle, Poison Oak, and Ivy.


Non-limiting examples of species that may be controlled include velvetleaf (Abutilon theophrasti), pigweed (Amaranthus spp.), buttonweed (Borreria spp.), oilseed rape, canola, indian mustard, etc. (Brassica spp.), commelina (Commelina spp.), filaree (Erodium spp.), sunflower (Helianthus spp.), morningglory (Ipomoea spp.), kochia (Kochia scoparia), mallow (Malva spp.), wild buckwheat, smartweed, etc. (Polygonum spp.), purslane (Portulaca spp.), russian thistle (Salsola spp.), sida (Sida spp.), wild mustard (Sinapis arvensis), cocklebur (Xanthium spp.), wild oat (Avena fatua), carpetgrass (Axonopus spp.), downy brome (Bromus tectorum), crabgrass (Digitaria spp.), barnyardgrass (Echinochloa crus-galli), goosegrass (Eleusine indica), annual ryegrass (Lolium multiflorum), rice (Oryza sativa), ottochloa (Ottochloa nodosa), bahiagrass (Paspalum notatum), canarygrass (Phalaris spp.), foxtail (Setania spp.), wheat (Triticum aestivum), corn (Zea mays), mugwort (Artemisia spp.), milkweed (Asclepias spp.), canada thistle (Cirsium arvense), field bindweed (Convolvulus arvensis), kudzu (Pueraria spp.), brachiaria (Brachiaria spp.), bermudagrass (Cynodon dactylon), yellow nutsedge (Cyperus esculentus), purple nutsedge (C. rotundus), quackgrass (Elymus repens), lalang (Imperata cylindrica), perennial ryegrass (Lolium perenne), guineagrass (Panicum maximum), dallisgrass (Paspalum dilatatum), reed (Phragmites spp.), johnsongrass (Sorghum halepense), cattail (Typha spp.), horsetail (Equisetum spp.), bracken (Pteridium aquilinum), blackberry (Rubus spp.) and gorse (Ulex europaeus).


Crop and other cultivated species may also be contacted with a composition of the invention. Non-limiting examples of cultivated plants include, but are not limited to, species from the genera Fragaria, Lotus, Medicago, Onobrychis, Trifolium, Trigonella, Vigna, Citrus, Linum, Geranium, Manihot, Daucus, Arabidopsis, Brassica, Raphanus, Sinapis, Atropa, Capsicum, Datura, Hyoscyamus, Lycopersicon, Nicotiana, Helianthus, Lactuca, Bromus, Asparagus, Antirrhinum, Hemerocallis, Nemesia, Pelargonium, Panicum, Pennisetum, Ranunculus, Senecio, Salpiglossis, Cucumis, Bromelia, Glycine, Lolium, Zea, Triticum, Sorghum, Ipomoea, Passifora, Cyclamen, Malus, Prumus, Rosa, Rubus, Populus, Santalum, Allium, Lilium, Narcissus, Ananas, Arachis, Phaseolus, Pisum, Oryza, Hordeum, Gossypium.


A common class of plants exploited in agriculture are vegetable crops, including artichokes, kohlrabi, arugula, leeks, asparagus, lettuce (e.g., head, leaf, romaine), bok choy, malanga, broccoli, melons (e.g., muskmelon, watermelon, crenshaw, honeydew, cantaloupe), brussels sprouts, cabbage, cardoni, carrots, napa, cauliflower, okra, onions, celery, parsley, chick peas, parsnips, chicory, Chinese cabbage, peppers, collards, potatoes, cucumber plants (marrows, cucumbers), pumpkins, cucurbits, radishes, dry bulb onions, rutabaga, eggplant, salsify, escarole, shallots, endive, garlic, spinach, green onions, squash, greens, beet (sugar beet and fodder beet), sweet potatoes, swiss-chard, horseradish, tomatoes, kale, turnips, and spices.


Other types of plants frequently finding commercial use include fruit and vine crops such as apples, apricots, cherries, nectarines, peaches, pears, plums, prunes, quince almonds, chestnuts, filberts, pecans, pistachios, walnuts, citrus, blueberries, boysenberries, cranberries, currants, loganberries, raspberries, strawberries, blackberries, grapes, avocados, bananas, kiwi, persimmons, pomegranate, pineapple, tropical fruits, pomes, melon, mango, papaya, and lychee.


Many of the most widely grown plants are field crop plants such as evening primrose, meadow foam, corn (field, sweet, popcorn), hops, jojoba, peanuts, rice, safflower, small grains (barley, oats, rye, wheat, etc.), sorghum, tobacco, kapok, leguminous plants (beans, lentils, peas, soybeans), oil plants (rape, mustard, poppy, olives, sunflowers, coconut, castor oil plants, cocoa beans, groundnuts), fiber plants (cotton, flax, hemp, jute), lauraceae (cinnamon, camphor), or plants such as coffee, sugarcane, tea, and natural rubber plants.


Another economically important group of plants are ornamental plants. Examples of commonly grown ornamental plants include alstroemeria (e.g., Alstoemeria brasiliensis), aster, azalea (e.g., Rhododendron sp.), begonias (e.g., Begonia sp.), bellflower, bouganvillea, cactus (e.g., Cactaceae schlumbergera truncata), camellia, carnation (e.g., Dianthus caryophyllus), chrysanthemums (e.g., Chrysanthemum sp.), clematis (e.g., Clematis sp.), cockscomb, columbine, cyclamen (e.g., Cyclamen sp.), daffodils (e.g., Narcissus sp.), false cypress, freesia (e.g., Freesia refracta), geraniums, gerberas, gladiolus (e.g., Gladiolus sp.), holly, hybiscus (e.g., Hibiscus rosasanensis), hydrangea (e.g., Macrophylla hydrangea), juniper, lilies (e.g., Lilium sp.), magnolia, miniroses, orchids (e.g., members of the family Orchidaceae), petunias (e.g., Petunia hybrida), poinsettia (e.g., Euphorbia pulcherima), primroses, rhododendron, roses (e.g., Rosa sp.), snapdragons (e.g., Antirrhinum sp.), shrubs, trees such as forest (broad-leaved trees and evergreens, such as conifers) and tulips (e.g., Tulipa sp.).


III. Antibiotics

Another embodiment of the invention concerns methods and compositions for the contemporaneous administration of ectophosphatase inhibitors and antibiotics. Antibiotics are any chemical of natural or synthetic origin that kill or inhibit the growth of other types cells. Many clinically-useful antibiotics are produced by microorganisms. Antibiotics are typically low molecular-weight (non-protein) molecules produced as secondary metabolites, mainly by microorganisms that live in the soil. Most of these microorganisms form some type of a spore or other dormant cell, and there is thought to be some relationship (besides temporal) between antibiotic production and the processes of sporulation. Among molds, the notable antibiotic producers are Penicillium and Cephalosporium, which are the main source of the beta-lactam antibiotics (penicillin and its relatives). In the Bacteria, the Actinomycetes, notably Streptomyces species, produce a variety of types of antibiotics including the aminoglycosides (e.g. streptomycin), macrolides (e.g. erythromycin), and the tetracyclines. Endospore-forming Bacillus species produce polypeptide antibiotics such as polymyxin and bacitracin. The table below (Table 1) is a summary of the classes of antibiotics and their properties including their biological sources.


As set forth in Table 2, certain aspects of the invention concern compositions comprising an ectophosphatase inhibitor and an antibiotic of a class selected from the group consisting of: beta-lactams (penicillins and cephalosporins); semisynthetic penicillin; clavulanic Acid; monobactams; carboxypenems; aminoglycosides; glycopeptides; lincomycins; macrolides; polypeptides; chloramphenicol; polyenes; rifamycins; tetracyclines; and semisynthetic tetracycline. Any ectophosphatase inhibitor may be used in conjuntion with these classes of antibiotics. In certain embodiments of the invention, the ectophosphatase inhibitor is selected from the group consisting of the compounds of formulas I-XX.

TABLE 2Classes of antibiotics and their propertiesSpectrum (effectiveChemical classExamplesBiological sourceagainst)Mode of actionBeta-lactamsPenicillin G,Penicillium notatum andGram-positive bacteriaInhibits steps in cell wall(penicillins andCephalothinCephalosporium species(peptidoglycan) synthesis andcephalosporins)murein assemblySemisyntheticAmpicillin,Gram-positive and Gram-Inhibits steps in cell wallpenicillinAmoxycillinnegative bacteria(peptidoglycan) synthesis andmurein assemblyClavulanic AcidClavamox isStreptomyces clavuligerusGram-positive and Gram-Suicide inhibitor of beta-lactamasesclavulanic acid plusnegative bacteriaamoxycillinMonobactamsAztreonamChromobacter violaceumGram-positive and Gram-Inhibits steps in cell wallnegative bacteria(peptidoglycan) synthesis andmurein assemblyCarboxypenemsImipenemStreptomyces cattleyaGram-positive and Gram-Inhibits steps in cell wallnegative bacteria(peptidoglycan) synthesis andmurein assemblyAminoglycosidesStreptomycinStreptomyces griseusGram-positive and Gram-Inhibit translation (protein synthesis)negative bacteriaGentamicinMicromonospora speciesGram-positive and Gram-Inhibit translation (protein synthesis)negative bacteria esp.PseudomonasGlycopeptidesVancomycinStreptomyces orientalesGram-positive bacteria,Inhibits steps in mureinesp. Staphylococcus(peptidoglycan) biosynthesis andaureusassemblyLincomycinsClindamycinStreptomyces lincolnensisGram-positive and Gram-Inhibits translation (proteinnegative bacteria esp.synthesis)anaerobic BacteroidesMacrolidesErythromycinStreptomyces erythreusGram-positive bacteria,Inhibits translation (proteinGram-negative bacteriasynthesis)not enterics,Neisseria, Legionella,MycoplasmaPolypeptidesPolymyxinBacillus polymyxaGram-negative bacteriaDamages cytoplasmic membranesBacitracinBacillus subtilisGram-positive bacteriaInhibits steps in murein(peptidoglycan) biosynthesis andassemblyPolyenesAmphotericinStreptomyces nodosusFungiInactivate membranes containingsterolsNystatinStreptomyces nourseiFungi (Candida)Inactivate membranes containingsterolsRifamycinsRifampicinStreptomyces mediterraneiGram-positive and Gram-Inhibits transcription (eubacterialnegative bacteria,RNA polymerase)MycobacteriumtuberculosisTetracyclinesTetracyclineStreptomyces speciesGram-positive and Gram-Inhibit translation (protein synthesis)negative bacteria,RickettsiasSemisyntheticDoxycyclineGram-positive and Gram-Inhibit translation (protein synthesis)tetracyclinenegative bacteria,Rickettsias Ehrlichia,BorelliaChloramphenicolChloramphenicolStreptomyces venezuelaeGram-positive and Gram-Inhibits translation (proteinnegative bacteriasynthesis)


A. Antimicrobial Agents Used in the Treatment of Infectious Disease


An important property of a clinically-useful antimicrobial agent, especially from the patient's point of view, is its selective toxicity, i.e., that the agent acts in some way that inhibits or kills bacterial pathogens but has little or no toxic effect on the animal taking the drug. This implies that the biochemical processes in the bacteria are in some way different from those in the animal cells, and that the advantage of this difference can be taken in chemotherapy. Antibiotics may have a cidal (killing) effect or a static (inhibitory) effect on a range of microbes. The range of bacteria or other microorganisms that are affected by a certain antibiotic are is expressed as its spectrum of action. Antibiotics effective against prokaryotes which kill or inhibit a wide range of Gram-positive and Gram-negative bacteria are said to be broad spectrum. If effective mainly against Gram-positive or Gram-negative bacteria, they are narrow spectrum. If effective against a single organism or disease, they are referred to as limited spectrum. In accordance with the invention, certain adverse effects of antibiotics may be minimized by use of en ectophosphatase inhibitor in combination with the antibiotic, thereby allowing use of lower doses of antibiotics.


B. Kinds of Antimicrobial Agents and Their Primary Modes of Action


In one embodiment of the invention, ectophosphatase inhibitors are used in conjunction with cell wall synthesis inhibitors. Cell wall synthesis inhibitors generally inhibit some step in the synthesis of bacterial peptidoglycan. Generally they exert their selective toxicity against eubacteria because human cells lack cell walls.


Beta lactam antibiotics contain a 4-membered beta lactam ring. They are the products of two groups of fungi, Penicillium and Cephalosporium molds, and are correspondingly represented by the penicillins and cephalosporins. The beta lactam antibiotics inhibit the last step in peptidoglycan synthesis, the final cross-linking between peptide side chains, mediated by bacterial carboxypeptidase and transpeptidase enzymes. Beta lactam antibiotics are normally bactericidal and require that cells be actively growing in order to exert their toxicity.


Natural penicillins, such as Penicillin G or Penicillin V, are produced by fermentation of Penicillium chrysogenum. They are effective against streptococcus, gonococcus and staphylococcus, except where resistance has developed. They are considered narrow spectrum since they are not effective against Gram-negative rods.


Semisynthetic penicillins date to 1959. Mold produces a main part of the penicillin molecule (6-aminopenicillanic acid) which can be modified chemically by the addition of side chains. Many of these compounds have been developed to have distinct benefits or advantages over penicillin G, such as increased spectrum of activity (effectiveness against Gram-negative rods), resistance to penicillinase, effectiveness when administered orally, etc. Amoxycillin and Ampicillin have broadened spectra against Gram-negatives and are effective orally; Methicillin is penicillinase-resistant.


Clavulanic acid is a chemical sometimes added to a semisynthetic penicillin preparation. Thus, amoxycillin plus clavulanate is clavamox or augmentin. The clavulanate is not an antimicrobial agent. It inhibits beta lactamase enzymes and has given extended life to penicillinase-sensitive beta lactams.


Although nontoxic, penicillins occasionally cause death when administered to persons who are allergic to them. In the U.S. there are 300-500 deaths annually due to penicillin allergy. In allergic individuals the beta lactam molecule attaches to a serum protein which initiates an IgE-mediated inflammatory response.


Cephalolsporins are beta lactam antibiotics with a similar mode of action to penicillins that are produced by species of Cephalosporium. The have a low toxicity and a somewhat broader spectrum than natural penicillins. They are often used as penicillin substitutes, against Gram-negative bacteria, and in surgical prophylaxis. They are subject to degradation by some bacterial beta-lactamases, but they tend to be resistant to beta-lactamases from S. aureus.


Bacitracin is a polypeptide antibiotic produced by Bacillus species. It prevents cell wall growth by inhibiting the release of the muropeptide subunits of peptidoglycan from the lipid carrier molecule that carries the subunit to the outside of the membrane Teichoic acid synthesis, which requires the same carrier, is also inhibited. Bacitracin has a high toxicity which precludes its systemic use. It is present in many topical antibiotic preparations, and since it is not absorbed by the gut, it is given to “sterilize” the bowel prior to surgery.


Cell membrane inhibitors disorganize the structure or inhibit the function of bacterial membranes. The integrity of the cytoplasmic and outer membranes is vital to bacteria, and compounds that disorganize the membranes rapidly kill the cells. However, due to the similarities in phospholipids in eubacterial and eukaryotic membranes, this action is rarely specific enough to permit these compounds to be used systemically. The only antibacterial antibiotic of clinical importance that acts by this mechanism is Polymyxin, produced by Bacillus polymyxis. Polymyxin is effective mainly against Gram-negative bacteria and is usually limited to topical usage. Polymyxins bind to membrane phospholipids and thereby interfere with membrane function. Polymyxin is occasionally given for urinary tract infections caused by Pseudomonas that are gentamicin, carbenicillin and tobramycin resistant. The balance between effectiveness and damage to the kidney and other organs is dangerously close, and the drug should only be given under close supervision in the hospital.


In accordance with the invention, ectophosphatase inhibitors may also be contemporaneously administered and formulated in compositions with antibiotics that are protein synthesis inhibitors. Many therapeutically useful antibiotics inhibit some step in the complex process of translation. The attack is at one of the events occurring on the ribosome, rather than the stage of amino acid activation or attachment to a particular tRNA. Most have an affinity or specificity for 70S (as opposed to 80S) ribosomes, and they achieve their selective toxicity in this manner. The most important antibiotics with this mode of action are the tetracyclines, chloramphenicol, the macrolides (e.g. erythromycin) and the aminoglycosides (e.g. streptomycin).


The aminoglycosides are products of Streptomyces species and are represented by streptomycin, kanamycin, tobramycin and gentamicin. These antibiotics exert their activity by binding to bacterial ribosomes and preventing the initiation of protein synthesis. Aminoglycosides have been used against a wide variety of bacterial infections caused by Gram-positive and Gram-negative bacteria. Streptomycin has been used extensively as a primary drug in the treatment of tuberculosis. Gentamicin is active against many strains of Gram-positive and Gram-negative bacteria, including some strains of Pseudomonas aeruginosa. Kanamycin (a complex of three antibiotics, A, B and C) is active at low concentrations against many Gram-positive bacteria, including penicillin-resistant staphylococci. Gentamicin and Tobramycin are mainstays for treatment of Pseudomonas infections. An unfortunate side effect of aminoglycosides has tended to restrict their usage: prolonged use is known to impair kidney function and cause damage to the auditory nerves leading to deafness.


The tetracyclines consist of eight related antibiotics which are all natural products of Streptomyces, although some can now be produced semisynthetically. Tetracycline, chlortetracycline and doxycycline are the best known. The tetracyclines are broad-spectrum antibiotics with a wide range of activity against both Gram-positive and Gram-negative bacteria. The tetracyclines act by blocking the binding of aminoacyl tRNA to the A site on the ribosome. Tetracyclines inhibit protein synthesis on isolated 70S or 80S (eukaryotic) ribosomes, and in both cases, their effect is on the small ribosomal subunit. However, most bacteria possess an active transport system for tetracycline that will allow intracellular accumulation of the antibiotic at concentrations 50 times as great as that in the medium. This greatly enhances its antibacterial effectiveness and accounts for its specificity of action, since an effective concentration cannot be accumulated in animal cells. Thus a blood level of tetracycline which is harmless


The tetracyclines have a remarkably low toxicity and minimal side effects when taken by animals. The combination of their broad spectrum and low toxicity has led to their overuse and misuse by the medical community and the wide-spread development of resistance has reduced their effectiveness. Nonetheless, tetracyclines still have some important uses, such as in the treatment of Lyme disease.


Chloramphenicol has a broad spectrum of activity but it exerts a bacteriostatic effect. It is effective against intracellular parasites such as the rickettsiae. Unfortunately, aplastic anemia, which is dose related develops in a small proportion (1/50,000) of patients. Chloramphenicol was originally discovered and purified from the fermentation of a Streptomyces, but currently it is produced entirely by chemical synthesis. Chloramphenicol inhibits the bacterial enzyme peptidyl transferase thereby preventing the growth of the polypeptide chain during protein synthesis.


Chloramphenicol is entirely selective for 70S ribosomes and does not affect 80S ribosomes. Its unfortunate toxicity towards the small proportion of patients who receive it is in no way related to its effect on bacterial protein synthesis. However, since mitochondria probably originated from prokaryotic cells and have 70S ribosomes, they are subject to inhibition by some of the protein synthesis inhibitors including chloroamphenicol. This likely explains the toxicity of chloramphenicol. The eukaryotic cells most likely to be inhibited by chloramphenicol are those undergoing rapid multiplication, thereby rapidly synthesizing mitochondria. Such cells include the blood forming cells of the bone marrow, the inhibition of which could present as aplastic anemia. Chloramphenicol was once a highly prescribed antibiotic and a number of deaths from anemia occurred before its use was curtailed. Now it is seldom used in human medicine except in life-threatening situations (e.g. typhoid fever).


The Macrolides are a family of antibiotics whose structures contain large lactone rings linked through glycoside bonds with amino sugars. The most important members of the group are erythromycin and oleandomycin. Erythromycin is active against most Gram-positive bacteria, Neisseria, Legionella and Haemophilus, but not against the Enterobacteriaceae. Macrolides inhibit bacterial protein synthesis by binding to the 50S ribosomal subunit. Binding inhibits elongation of the protein by peptidyl transferase or prevents translocation of the ribosome or both. Macrolides are bacteriostatic for most bacteria but are cidal for a few Gram-positive bacteria.


In further embodiments of the invention, ectophosphatase inhibitors may be contemporaneously administered and formulated in compositions with antibiotics that affect nucleic acids, including chemotherapeutic agents that affect the synthesis of DNA or RNA, or can bind to DNA or RNA so that their messages cannot be read. In either case, this can block the growth of cells. The majority of these drugs are unselective, however, and affect animal cells and bacterial cells alike and therefore have no therapeutic application. Two nucleic acid synthesis inhibitors which have selective activity against prokaryotes and some medical utility are nalidixic acid and rifamycins.


Nalidixic acid is a synthetic chemotherapeutic agent which has activity mainly against Gram-negative bacteria. Nalidixic acid belongs to a group of compounds called quinolones. Nalidixic acid is a bactericidal agent that binds to the DNA gyrase enzyme (topoisomerase) which is essential for DNA replication and allows supercoils to be relaxed and reformed. Binding of the drug inhibits DNA gyrase activity.


Some quinolones penetrate macrophages and neutrophils better than most antibiotics and are thus useful in treatment of infections caused by intracellular parasites. However, the main use of nalidixic acid is in treatment of lower urinary tract infections (UTI). The compound is unusual in that it is effective against several types of Gram-negative bacteria such as E. coli, Enterobacter aerogentes, K. pneumoniae and Proteus species which are common causes of UTI. It is not usually effective against Pseudomonas aeruginosa, and Gram-positive bacteria are resistant.


The rifamycins are also the products of Streptomyces. Rifampicin is a semisynthetic derivative of rifamycin that is active against Gram-positive bacteria (including Mycobacterium tuberculosis) and some Gram-negative bacteria. Rifampicin acts quite specifically on eubacterial RNA polymerase and is inactive towards RNA polymerase from animal cells or towards DNA polymerase. The antibiotic binds to the beta subunit of the polymerase and apparently blocks the entry of the first nucleotide which is necessary to activate the polymerase, thereby blocking mRNA synthesis. It has been found to have greater bactericidal effect against M. tuberculosis than other anti-tuberculosis drugs, and it has largely replaced isoniazid as one of the front-line drugs used to treat the disease, especially when isoniazid resistance is indicated. It is effective orally and penetrates well into the cerebrospinal fluid and is therefore useful for treatment of tuberculosis meningitis and meningitis caused by Neisseria meningitidis.


In accordance with the invention, ectophosphatase inhibitors may also be administered with competitive inhibitors, including mostly all synthetic chemotherapeutic agents. Most are “growth factor analogs” which are structurally similar to a bacterial growth factor but which do not fulfill its metabolic function in the cell. Some are bacteriostatic and some are bactericidal.


Sulfonamides were originally introduced as chemotherapeutic agents, one of which, prontosil, had the effect of curing mice with infections caused by beta-hemolytic streptococci. Chemical modifications of the compound sulfanilamide gave compounds with even higher and broader antibacterial activity. The resulting sulfonamides have broadly similar antibacterial activity, but differ widely in their pharmacological actions. Bacteria which are almost always sensitive to the sulfonamides include Streptococcus pneumoniae, beta-hemolytic streptococci and E. coli. The sulfonamides have been extremely useful in the treatment of uncomplicated UTI caused by E. coli, and in the treatment of meningococcal meningitis, because they cross the blood-brain barrier.


The sulfonamides (e.g. Gantrisin) and Trimethoprim are inhibitors of the bacterial enzymes required for the synthesis of tetrahydofolic acid (THF), the vitamin form of folic acid essential for 1-carbon transfer reactions. Sulfonamides are structurally similar to para aminobenzoic acid (PABA), the substrate for the first enzyme in the THF pathway, and they competitively inhibit that step. Trimethoprim is structurally similar to dihydrofolate (DHF) and competitively inhibits the second step in THF synthesis mediated by the DHF reductase. Animal cells do not synthesize their own folic acid but obtain it in a preformed fashion as a vitamin. Since animals do not make folic acid, they are not affected by these drugs, which achieve their selective toxicity for bacteria on this basis.


Three additional synthetic chemotherapeutic agents have been used in the treatment of tuberculosis: isoniazid (INH), paraaminosalicylic acid (PAS), and ethambutol. The usual strategy in the treatment of tuberculosis has been to administer a single antibiotic (historically streptomycin, but now, most commonly, rifampicin is given) in conjunction with INH and ethambutol. Since the tubercle bacillus rapidly develops resistance to the antibiotic, ethambutol and INH are given to prevent outgrowth of a resistant strain. It must also be pointed out that the tubercle bacillus rapidly develops resistance to ethambutol and INH if either drug is used alone. Ethambutol inhibits incorporation of mycolic acids into the mycobacterial cell wall. Isoniazid has been reported to inhibit mycolic acid synthesis in mycobacteria and since it is an analog of pyridoxine (Vitamin B6) it may inhibit pyridoxine catalyzed reactions as well. Isoniazid is activated by a mycobacterial peroxidase enzyme and destroys several targets in the cell. PAS is an anti-folate. PAS was once a primary anti-tuberculosis drug, but now it is a secondary agent, having been largely replaced by ethambutol.


C. Inhibition of Drug Resistance in Microorganisms to Treat Infection


The present invention also relates to methods for inhibiting or ameliorating infection in animals and humans caused by microorganisms. For example, treatment of bacterial and fungal infections may be augmented or effected using inhibitory mechanisms against an ectophosphatase to modify the ATP gradient across biological membranes. The invention is useful in the inhibition or amelioration of a wide range of infections including, but not limited to, gram negative bacterial infection including gram-negative sepsis, gram-negative endotoxin-related hypotension and shock, rabies, cholera, tetanus, lymes disease, tuberculosis, Candida albicans, Chlamydia, etc.


The inhibition or amelioration of the infections may involve the administration of an anti-microbial agent (such as an antibiotic or an antifungal agent) with the concurrent administration of the aforementioned compositions. Additionally, inhibitors of ectophosphatases or ABC transporters may be administered via a physiologically acceptable carrier as described above. In one embodiment of the invention, the inhibitor of ectophosphatase is selected from the compounds represented by formulas I-XX.


Certain aspects of the current invention thus concern the inhibition of cell growth by contacting a cell with an inhibitor of an ectophosphatase with contemporaneous administration of other agents capable of inhibiting cell growth or killing the cell. In this manner, therapeutic benefit may be obtained for the treatment of bacterial infections. Examples of types of bacteria that could be inhibited and bacterial infections that could potentially be treated or prevented with the invention, include, but are not limited to, the 83 or more distinct serotypes of pneumococci, streptococci such as S. pyogenes, S. agalactiae, S. equi, S. canis, S. bovis, S. equinus, S. anginosus, S. sanguis, S. salivarius, S. mitis, S. mutans, other viridans streptococci, peptostreptococci, other related species of streptococci, enterococci such as Enterococcus faecalis, Enterococcus faecium, Staphylococci, such as Staphylococcus epidermidis, Staphylococcus aureus, particularly in the nasopharynx, Hemophilus influenzae, pseudomonas species such as Pseudomonas aeruginosa, Pseudomonas pseudomallei, Pseudomonas mallei, brucellas such as Brucella melitensis, Brucella suis, Brucella abortus, Bordetella pertussis, Neisseria meningitidis, Neisseria gonorrhoeae, Moraxella catarrhalis, Corynebacterium diphtheriae, Corynebacterium ulceratis, Corynebacterium pseudotuberculosis, Corynebacterium pseudodiphtheriticum, Corynebacterium urealyticum, Corynebacterium hemolyticum, Corynebacterium equi, etc. Listeria monocytogenes, Nocordia asteroides, Bacteroides species, Actinomycetes species, Treponema pallidum, Leptospirosa species and related organisms. The invention may also find use, for example, against gram negative bacteria such as Klebsiella pneumoniae, Escherichia coli, Proteus, Serratia species, Acinetobacter, Yersinia pestis, Francisella tularensis, Enterobacter species, Bacteriodes and Legionella species and the like.


IV. Chemotherapeutics

A variety of chemotherapeutic agents are suitable for use with the invention and are known to those of skill in the art. In accordance with the invention, therapeutic benefit may be obtained by contemporaneous administration of one or more ectophosphatase inhibitor and one or more such chemotherapeutic agent(s). Co-administration of chemotherapeutics with ectophosphatase inhibitors in accordance with the invention may be used to increase therapeutic effectiveness of a chemotherapeutic and may allow use of lowered doses. Such techniques may further allow treatment of chemotherapy-resistant tumor cells.


As will be understood by those of ordinary skill in the art, the appropriate doses of chemotherapeutic agents will be generally around those already employed in clinical therapies wherein the chemotherapeutics are administered alone or in combination with other chemotherapeutics. By way of example only, agents such as cisplatin, and other DNA alkylating agents may be used with an ectophosphatase inhibitor. Cisplatin has been widely used to treat cancer, with efficacious doses used in clinical applications of 20 mg/m2 for 5 days every three weeks for a total of three courses. Cisplatin is not absorbed orally and must therefore be delivered via injection intravenously, subcutaneously, intratumorally or intraperitoneally.


Further agents for use with ectophosphatase inhibitors in accordance with the invention include, for example, compounds that interfere with DNA replication, mitosis and chromosomal segregation. Such chemotherapeutic compounds include adriamycin, also known as doxorubicin, etoposide, verapamil, podophyllotoxin, and the like. Widely used in a clinical setting for the treatment of neoplasms, these compounds are administered through bolus injections intravenously at doses ranging from 25-75 mg/m2 at 21 day intervals for adriamycin, to 35-50 mg/m2 for etoposide intravenously or double the intravenous dose orally.


Agents that disrupt the synthesis and fidelity of polynucleotide precursors also may be used with ectophosphatase inhibitors. Particularly useful are agents that have undergone extensive testing and are readily available. As such, agents such as 5-fluorouracil (5-FU) are preferentially used by neoplastic tissue, making this agent particularly useful for targeting to neoplastic cells. Although quite toxic, 5-FU is applicable in a wide range of carriers, including topical, with intravenous administration in doses ranging from 3 to 15 mg/kg/day being commonly used.


Exemplary and non-limiting chemotherapeutic agents for use in combination with an ectophosphatase inhibitor in accordance with the invention are listed in Table 3. Accordingly, compositions comprising these agents and one or more ectophosphatase inhibitor(s) form one part of the invention, as do methods for the administration thereof. Each of the agents listed below are exemplary and by no means limiting. In this regard, the skilled artisan is directed to “Remington's Pharmaceutical Sciences” 15th Edition, chapter 33, in particular pages 624-652. Some variation in dosage will necessarily occur depending on the condition of the subject being treated. The person responsible for administration will, in any event, determine the appropriate dose for the individual subject. Moreover, for human administration, preparations should meet sterility, pyrogenicity, general safety and purity standards as required by FDA Office of Biologics standards.


Specifically contemplated by the inventors are compositions comprising and ectophosphatase inhibitor and a chemotherapeutic agent set forth in Table 3, as well as methods comprising the use thereof

TABLE 3Chemotherapeutic Agents Useful In Neoplastic DiseaseNONPROPRIETARYTYPE OFNAMESCLASSAGENT(OTHER NAMES)DISEASEMechlorethamine (HN2)Hodgkin's disease,non-Hodgkin's lymphomasNitrogenCyclophosphamideAcute and chronicMustardsIfosfamidelymphocytic leukemias,Hodgkin's disease,non-Hodgkin's lymphomas,multiple myeloma,neuroblastoma, breast, ovary,lung, Wilms' tumor, cervix,testis, soft-tissue sarcomasMelphalan (L-sarcolysin)Multiple myeloma, breast,ovaryChlorambucilChronic lymphocyticleukemia, primarymacroglobulinemia,Hodgkin's disease,non-Hodgkin's lymphomasAlkylatingEthylenimenesHexamethylmelamineOvaryAgentsandMethylmelaminesThiotepaBladder, breast, ovaryAlkylBusulfanChronic granulocytic leukemiaSulfonatesCarmustine (BCNU)Hodgkin's disease,non-Hodgkin's lymphomas,primary brain tumors, multiplemyeloma, malignantmelanomaNitrosoureasLomustine (CCNU)Hodgkin's disease,non-Hodgkin's lymphomas,primary brain tumors,small-cell lungSemustinePrimary brain tumors,(methyl-CCNU)stomach, colonStreptozocinMalignant pancreatic(streptozotocin)insulinoma, malignantcarcinoidTriazinesDacarbazine (DTIC;Malignant melanoma,dimethyltriazenoimidazolecarboxamide)Hodgkin's disease, soft-tissuesarcomasAntimetabolitesFolic AcidMethotrexateAcute lymphocytic leukemia,Analogs(amethopterin)choriocarcinoma, mycosisfungoides, breast, head andneck, lung, osteogenicsarcomaPyrimidineFluouracilBreast, colon, stomach,Analogs(5-fluorouracil; 5-FU)pancreas, ovary, head andFloxuridineneck, urinary bladder,(fluorode-oxyuridine;premalignant skin lesionsFUdR)(topical)Antimetabolites,Cytarabine (cytosineAcute granulocytic and acutecontinuedarabinoside)lymphocytic leukemiasMercaptopurineAcute lymphocytic, acute(6-mercaptopurine;granulocytic and chronic6-MP)granulocytic leukemiasPurine AnalogsThioguanineAcute granulocytic, acuteand Related(6-thioguanine; TG)lymphocytic and chronicInhibitorsgranulocytic leukemiasPentostatinHairy cell leukemia, mycosis(2-deoxycoformycin)fungoides, chroniclymphocytic leukemiaVinblastine (VLB)Hodgkin's disease,non-Hodgkin's lymphomas,breast, testisVinca AlkaloidsVincristineAcute lymphocytic leukemia,neuroblastoma, Wilms' tumor,rhabdomyosarcoma,Hodgkin's disease,non-Hodgkin's lymphomas,small-cell lungEpipodophyllotoxinsEtoposideTestis, small-cell lung andTertiposideother lung, breast, Hodgkin'sdisease, non-Hodgkin'slymphomas, acutegranulocytic leukemia,Kaposi's sarcomaNaturalDactinomycinChoriocarcinoma, Wilms'Products(actinomycin D)tumor, rhabdomyosarcoma,testis, Kaposi's sarcomaDaunorubicinAcute granulocytic and acute(daunomycin;lymphocytic leukemiasrubidomycin)AntibioticsDoxorubicinSoft-tissue, osteogenic andother sarcomas; Hodgkin'sdisease, non-Hodgkin'slymphomas, acute leukemias,breast, genitourinary, thyroid,lung, stomach, neuroblastomaBleomycinTestis, head and neck, skin,esophagus, lung andgenitourinary tract; Hodgkin'sdisease, non-Hodgkin'slymphomasAntibiotics,PlicamycinTestis, malignantcontinued(mithramycin)hypercalcemiaNaturalMitomycin (mitomycinStomach, cervix, colon, breast,Products,C)pancreas, bladder, head andcontinuedneckEnzymesL-AsparaginaseAcute lymphocytic leukemiaBiologicalInterferon alfaHairy cell leukemia., Kaposi'sResponsesarcoma, melanoma,Modifierscarcinoid, renal cell, ovary,bladder, non-Hodgkin'slymphomas, mycosisfungoides, multiple myeloma,chronic granulocytic leukemiaPlatinumCisplatin (cis-DDP)Testis, ovary, bladder, headCoordinationCarboplatinand neck, lung, thyroid,Complexescervix, endometrium,neuroblastoma, osteogenicsarcomaAnthracenedioneMitoxantroneAcute granulocytic leukemia,breastMiscellaneousSubstituted UreaHydroxyureaChronic granulocyticAgentsleukemia, polycythemia vera,essental thrombocytosis,malignant melanomaMethylProcarbazineHodgkin's diseaseHydrazine(N-methylhydrazine,DerivativeMIH)AdrenocorticalMitotane (o, p′-DDD)Adrenal cortexSuppressantAminoglutethimideBreastAdrenocorticosteroidsPrednisone (several otherAcute and chronicequivalent preparationslymphocytic leukemias,available)non-Hodgkin's lymphomas,Hodgkin's disease, breastHormones andProgestinsHydroxyprogesteroneEndometrium, breastAntagonistscaproateMedroxyprogesteroneacetateMegestrol acetateEstrogensDiethylstilbestrolBreast, prostateEthinyl estradiol (otherpreparations available)AntiestrogenTamoxifenBreastAndrogensTestosterone propionateBreastFluoxymesterone (otherpreparations available)AntiandrogenFlutamideProstateGonadotropin-releasingLeuprolideProstatehormoneanalog


Administration of compositions provided by the invention may be local or systemic, using a suitable physiological carrier. Other compounds which aid in the uptake or stability of these agents, or which have beneficial activity, may also be included in the formulations of the invention. Certain embodiments of the invention thus provide pharmaceutical composition comprising an ectophosphatase inhibitor. The composition may further comprise, in certain embodiments, a cytotoxic agent, including a chemotherapeutic agent set forth herein. For example, by contacting a tumor cell either alone with the ectophosphatase inhibitor or in combination with one or more chemotherapeutic agents, therapeutic benefit may be obtained. Particular benefit may be obtained where a tumor cell is resistant to at least one chemotherapeutic agent. This may enhance the overall anti-tumor activity achieved by therapy, and/or may be used to prevent or combat multi-drug tumor resistance.


V. Assays and Methods for Screening Active Compounds

In one embodiment of the invention, assays are provided for screening compositions comprising combinations of ectophosphatase inhibitors and a selected cytotoxic agent, for example, a herbicide, fungicide, antibiotic, insecticide or chemotherapeutic agent. A number of assay formats are known to those of skill in the art and may be used in this regard. These include assays of biological activities as well as assays of chemical properties. The results of these assays provide important inferences as to the properties of compounds as well as their potential applications in treating human or other mammalian patients for infection and hyperproliferative diseases as well as in various agricultural applications. Assays deemed to be of particular utility in this regard include in vivo and in vitro screens of activity and immunoassays.


(i) Screening for Herbicidal Activity


One aspect of the current invention provides herbicidal compositions having improved herbicidal activity. In accordance with the invention, assays for herbicidal activity may be used to asses the relative efficacy of combinations of ectophosphatase inhibitors and herbicidal agents. Numerous assays formats for analyzing herbicidal activity are known to those of skill in the art and may be used in this regard. A straightforward means for testing activity comprises the serial application of test compositions to plants and/or plant parts, for example, by leaf painting. Plants are otherwise grown under comparable conditions, followed by serial applications of test and control compositions are applied. Control treatments may be used comprising herbicide compositions lacking ectophosphatase inhibitors, thereby identifying the presence of absence of activity as a syngerist. Herbicidal activity is then measured by analysis of the effect of the composition on plant viability.


Commercial herbicide formulations are well known to those of skill in the art and will generally be used in assays. However, it will typically be preferred to dilute herbicidal compositions and/or administer reduced amounts of the compositions such that the relative herbicidal activity of a composition may be quantified. Reductions in the lethality of herbicidal compositions allows the identification of effectiveness between herbicidal compositions. Thus, in particular embodiments of the invention, test and control compositions are administered in rates and/or amounts of from about 90% to about 5% of the commercial application rate for a given herbicide.


Following application of herbicidal test compositions, herbicidal activity and effectiveness is measured. Through comparisons with applications of control compositions, the effectiveness of the compositions may be determined.


Tests may be carried out on whole plants as well as plant parts or cell. For example, plant cells in tissue culture may be screened for herbicidal activity. The preparation of plant tissue-cultures is well known to those of skill in the art.


(ii) In Vivo Assays


The present invention encompasses the use of various animal models. Here, the identity seen between human and mouse provides an excellent opportunity to examine the function of a potential therapeutic agent, for example, an antiinfective or chemotherapeutic administered in combination with an ectophosphatase inhibitor. In the case of chemotherapeutics, one can utilize cancer models in mice that will be highly predictive of cancers in humans and other mammals. These models may employ the orthotopic or systemic administration of tumor cells to mimic primary and/or metastatic cancers. Alternatively, one may induce cancers in animals by providing agents known to be responsible for certain events associated with malignant transformation and/or tumor progression. Similarly, numerous animal models are available for analysis of antinfectives, including insecticides, antibiotics and antifungal agents. In this manner, all that is commonly required is infection of the relevant animal with a target infective agent and analysis of therapeutic benefit relative to prior antiinfective compositions.


Treatment of animals with test compositions will involve the administration of the composition, in an appropriate form, to the animal. Administration will be by any route the could be utilized for clinical or non-clinical purposes, including but not limited to oral, nasal, buccal, rectal, vaginal or topical. Alternatively, administration may be by intratracheal instillation, bronchial instillation, intradermal, subcutaneous, intramuscular, intraperitoneal or intravenous injection. Specifically contemplated are systemic intravenous injection, regional administration via blood or lymph supply and intratumoral injection.


Determining the effectiveness of a compound in vivo may involve a variety of different criteria. Such criteria include, but are not limited to, survival, reduction of tumor burden or mass, arrest or slowing of tumor progression, elimination of tumors, inhibition or prevention of metastasis, increased activity level, improvement in immune effector function and improved food intake. Through comparisons of active agents alone and active agents in combination with ectophosphatase inhibitors, synergistic combinations may be readily confirmed.


(iii) Confirmatory In Vivo and Clinical Studies


It will be understood by those of skill in the art that therapeutic compositions should generally be tested in an in vivo setting prior to use in a human subject. Such pre-clinical testing in animals is routine in the art. To conduct such confirmatory tests, all that is required is an art-accepted animal model of the disease in question, such as an animal bearing a solid tumor or infective agent. Any animal may be used in such a context, such as, e.g., a mouse, rat, guinea pig, hamster, rabbit, dog, chimpanzee, or such like. Studies using small animals such as mice are widely accepted as being predictive of clinical efficacy in humans, and such animal models may thus find use in the context of the present invention as they are readily available and relatively inexpensive, at least in comparison to other experimental animals.


The manner of conducting an experimental animal test will be straightforward to those of ordinary skill in the art. All that is required to conduct such a test is to establish equivalent treatment groups, and to administer the test compounds to one group while various control studies are conducted in parallel on the equivalent animals in the remaining group or groups. One monitors the animals during the course of the study and, ultimately, one sacrifices the animals to analyze the effects of the treatment.


In the context of the treatment of tumors, it is contemplated that effective amounts of chemotherapeutic compositions will be those that generally result in at least about 10% of the cells within a tumor exhibiting cell death or apoptosis. Preferably, at least about 20%, about 30%, about 40%, or about 50%, of the cells at a particular tumor site will be killed. Most preferably, 100% of the cells at a tumor site will be killed.


The extent of cell death in a tumor is assessed relative to the maintenance of healthy tissues in all of the areas of the body. It will be preferable to use doses of chemotherapeutic compositions capable of inducing at least about 60%, about 70%, about 80%, about 85%, about 90%, about 95% up to and including 100% tumor necrosis, so long as the doses used do not result in significant side effects or other untoward reactions in the animal. All such determinations can be readily made and properly assessed by those of ordinary skill in the art. For example, attendants, scientists and physicians can utilize such data from experimental animals in the optimization of appropriate doses for human treatment. In subjects with advanced disease, a certain degree of side effects can be tolerated. However, patients in the early stages of disease can be treated with more moderate doses in order to obtain a significant therapeutic effect in the absence of side effects. The effects observed in such experimental animal studies should preferably be statistically significant over the control levels and should be reproducible from study to study.


Those of ordinary skill in the art will further understand that combinations and doses of the compositions provided by the invention that result in tumor-specific necrosis towards the lower end of the effective ranges may nonetheless still be useful in connection with the present invention. For example, in embodiments where a continued application of the active agents is contemplated, an initial dose that results in only about 10% necrosis will nonetheless be useful, particularly as it is often observed that this initial reduction “primes” the tumor to further destructive assault upon subsequent re-application of the therapy. In any event, even if upwards of about 40% or so tumor inhibition is not ultimately achieved, it will be understood that any induction, of thrombosis and necrosis is nonetheless useful in that it represents an advance over the state of the patients prior to treatments. Still further, it is contemplated that a dose which prevents or decreases the likelihood of either metastasis or de novo carcinogenesis would also be of therapeutic benefit to a patient receiving the treatment.


As discussed above in connection with the in vitro test system, it will naturally be understood that combinations of agents intended for use together should be tested and optimized together. The compositions of the invention can be straightforwardly analyzed in the combinations set forth herein. Analysis of the combined effects of such agents would be determined and assessed according to the guidelines set forth above.


(iv) In Vitro Assays


In one embodiment of the invention, screening of a composition provided by the invention is conducted in vitro to identify those compounds capable of synergizing therapeutic agents, including cytotoxic agents such as antibiotics, fungicides and chemotherapeutic agents, as well as other types of biologically-active agents. In the case of killing of tumor cells, cytotoxicity is generally exhibited by necrosis or apoptosis. Necrosis is a relatively common pathway triggered by external signals. During this process, the integrity of the cellular membrane and cellular compartments is lost. On the other hand, apoptosis, or programmed cell death, is a highly organized process of morphological events that is synchronized by the activation and deactivation of specific genes (Thompson et al., 1992; Wyllie, 1985). In the case of pesticides, the selective cytotoxic action against the infective agent, including an insect, bacterial or fungal pathogen, is typically analyzed.


An efficacious means for in vitro assaying of cytoxicity comprises the systematic exposure of a panel of cells to selected compositions. For example, in the case of cancer, many tumor cell lines are available for implementing assays, including human ovarian, leukemic, breast, prostate, melanoma and renal cancer cells.


In vitro determinations of the efficacy of a compound in killing tumor cells may be achieved, for example, by assays of the expression and induction of various genes involved in cell-cycle arrest (p21, p27; inhibitors of cyclin dependent kinases) and apoptosis (bcl-2, bcl-xL and bax). To carry out this assay, cells are treated with the test compound, lysed, the proteins isolated, and then resolved on SDS-PAGE gels and the gel-bound proteins transferred to nitrocellulose membranes. The membranes are first probed with the primary antibodies (e.g., antibodies to p21, p27, bax, bcl-2 and bcl-x1, etc.) and then detected with diluted horseradish peroxidase conjugated secondary antibodies, and the membrane exposed to ECL detection reagent followed by visualization on ECL-photographic film. Through analysis of the relative proportion of the proteins, estimates may be made regarding the percent of cells in a given stage, for example, the G0/G1 phase, S phase or G2/M phase.


VI. EXAMPLES

The following examples are included to demonstrate preferred embodiments of the invention. It should be appreciated by those of skill in the art that the techniques disclosed in the examples which follow represent techniques discovered by the inventor to function well in the practice of the invention, and thus can be considered to constitute preferred modes for its practice. However, those of skill in the art should, in light of the present disclosure, appreciate that many changes can be made in the specific embodiments which are disclosed and still obtain a like or similar result without departing from the spirit and scope of the invention.


Example 1
Inhibition of Antibiotic Resistant Bacteria with Ectophosphatase Inhibitors

A. Summary of Protocol and Results


The purpose of this study was to evaluate various ectophosphatase inhibitor compounds for any potentiating effect or resistance reversal with methicillin resistant Staphylococcus aureus (MRSA). Two strains of Staphylococcus aureus were obtained from the American Type Culture Collection (ATCC). Those obtained were a previously characterized methicillin resistant strain (# 43300) and a previously characterized methicillin sensitive strain (# 29213) to serve as a control. Strains were received as lyophilized pellets and were rehydrated according to the ATCC Product Information Sheet using Trypticase Soy Broth.


Mueller-Hinton agar plates were prepared containing 1 of 6 inhibitor compounds investigated. The compounds were dissolved in DMSO at concentrations of 20 mg/ml. 25 μl of this stock solution was added to 25 mls of media just prior to cooling to solidification to produce plates containing 20 μg/ml of inhibitor compound. Control plates containing 25 μl DMSO only were also prepared in the same fashion.


For each of the two strains, 5 isolated colonies were picked from overnight culture plates and used to inoculate a 0.85% NaCl solution. The turbidity of each culture was adjusted using 0.85% NaCl until the turbidity of each matched a 0.5 McFarland turbidity standard. Each strain was swabbed onto control plates. The MRSA strain was swabbed also onto the inhibitor plates. Plates were allowed to dry for 5 minutes. A disk containing 5 μg of methicillin (obtained for the purpose of susceptibility testing from Bioanalyse Co., Ltd.) was placed onto the surface of all plates. Plates were incubated at 37° C.


Plates were read after 24 hours. It was noticed at this time that one plate, containing inhibitor compound NGXT1914 (Formula XV), was clear—there was no bacterial growth at all. All other plates had confluent growth except at the zone of inhibition of the methicillin disk.


Protocols for the studies were according to NCCLS guidelines (M2-A7, M100-S11) for antimicrobial susceptibility testing. Methodology for the serum bactericidal test was according to (Tentative Guideline) NCCLS M21-T, 1992. Methods for determining bactericidal activity of antimicrobial agents was according to (Tentative Guideline) NCCLS M26-T.1992. Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically. 3rd ed. NCCLS M7-A3.1993. Protocols for evaluating dehydrated Mueller-Hinton agar were according to NCCLS M6-A, 1996. Performance standards for antimicrobial susceptibility testing were according to NCCLS M100-S8, 1998. The screening test for Oxacillin-resistant Staphylococci was according to NCCLS M7-A4. Performance standards for antimicrobial disk and dilution susceptibility tests for bacteria isolated from animals was according to (Approved Standard) NCCLS M31-A. Performance standards for antimicrobial susceptibility testing were according to NCCLS M100-S8.1998. Screening test for Oxacillin-resistant Staphylococci was according to NCCLS M7-A4 Susceptibility test panels.


B. Confirmation of Results


In order to ascertain whether the result with inhibitor NGXT1914 was artifactual, both MRSA and MSSA were tested on Mueller-Hinton agar plates containing varying concentrations of NGXT1914. First, plates were prepared as above with the following concentrations of inhibitor compound: 0 μg/ml (DMSO controls), 1 μg/ml, 5 μg/ml, 10 μg/ml, and 25 μg/ml. Inhibitor concentrations were prepared such that all plates contained 25 μl total DMSO. For each of the two strains, 5 isolated colonies were picked from fresh overnight culture plates and used to inoculate a 0.85% NaCl solution. The turbidity of each culture was adjusted using 0.85% NaCl until the turbidity of each matched a 0.5 McFarland turbidity standard. Both strains were each swabbed onto both control and inhibitor plates. Plates were allowed to dry for 5 minutes and were placed into the incubator. Plates were read after 24 hours (Dec. 7, 2001). The results were as follows:

Concentration(μg/ml NGXT1914)Result25 μg/mlNo growth at all for either strain10 μg/mlNo growth at all for MRSA strain. Somesmall isolated colonies on the MSSA plate. 5 μg/mlOnly a few small colonies on the MRSAplate. Confluent growth on the MSSAplate. 1 μg/mlConfluent growth on both plates.ControlsConfluent growth on both plates.


C. Conclusions


Inhibitor NGXT 1914 inhibits growth of both resistant and sensitive Staph strains, however it is more effective against the methicillin resistant strain. This compound was tested with other cell types (mammalian cell lines, plants (Arabidopsis thaliana) yeast, Pseudomonas aeruginosa) and has not inhibited growth of any cell line or organism at the concentrations tested. Since NGXT1914 is an ectophosphatase inhibitor, it is possible that Staph, particularly the MRSA, is dependent on a phosphatase that is an ideal substrate for NGXT1914. The results obtained indicated that NGXT1914 was more effective against MRSA versus MSSA than previously identified compounds.


Example 2
Inhibition of Chemotherapy-Resistant Tumor Cells with an Ectophosphatase Inhibitor

In order to determine the effect of ectophosphatase inhibitors on tumor cells resistant to a chemotherapeutic agent, 2 breast cancer tumor cell lines were tested, a vinblastine resistant line (SW-13Vb003) and its vinblastine sensitive parent line, SW-13. A standard 4 day incubation at 37° C. and 5% CO2 was used. IC50 tests (NTT) were done using standard methodology in 96 well plate format with inhibitor concentrations ranging from 0-90 μg/ml (DMEM media). Results showed that 3 of the inhibitor compounds tested, NGXT194 (Formula VI), NGXT196 (Formula VIII), and NGXT1915 (Formula X), produced lower IC50 values with the resistant cell line than with the sensitive line. For NGXT194, SW-13 was sensitive at 20 μg/ml, whereas the vinblastine resistant line SW-13Vb003 was sensitive at 10 μg/ml. For NGXT196, SW-13 was sensitive at 30 μg/ml, whereas the vinblastine resistant line SW-13Vb003 was sensitive at 10 μg/ml. For NGXT1915, SW-13 was sensitive at 50 μg/ml, whereas the vinblastine resistant line SW-13Vb003 was sensitive at 20 μg/ml.


Based on the inventors previous findings concerning the role of ectophosphatases in drug resistance, it seems likely that many resistant cells have upregulated phosphatases and that inhibiting a phosphatase critical to maintaining these cells could result in cell death. One hypothesis is that once these phosphatase enzymes are upregulated or are used in drug resistance their function becomes one that is vital to the cell. Since this phenomenon has been seen now in a bacterial resistance model it might be expected that the ectophosphatase inhibiting compounds could preferentially kill other types of resistant cells or act as biocides to certain cells.


Example 3
Over-Expression of Ectophosphatase does not Increase the Cellular Uptake of Adenosine

A. Materials and Methods


Transgenic Plant Construction: psNTP9 (Pisum Sativum apyrase, GenBank accession #Z32743) was subcloned as a Sall to Xbal fragment into pKYLX71 (Schardl et al, 1987, supra.). This plasmid was transformed into A. tumefaciens GV3101 [pMP90] pKYLX71 (Koncz and Shell, 1986), which was used to infect root call from Ws ecotype Arabidopsis thaliana under kanamycin selection (Valvekens et al., 1992). Four individual lines, obtained from separate calli, were propagated to the third generation (T3).


Subcellular Apyrase Distribution in Pea: Etiolated pea plumules served as the tissue source for nuclei and cytoplasm isolation as described by Chen and Roux (Plant Physiol. 81:609-612 (1986)). Plasma membrane was prepared from 30 g of pea root tissue (Zhu Mei Jun and Chen Jia; 1995, Acta Botanica Sinica 37:942-949). Western analysis was performed on 15-30 pg of protein from cytoplasm, plasma membrane and nuclei using a polyclonal anti-apyrase antibody raised against the purified pea protein (Tong et al., 1993). To determine the orientation of the pea apyrase in the pea plasma membrane, outside-out vesicles were prepared and the accessibility of the enzyme was determined by selective trypsin proteolysis, or membrane shaving, followed by activity assays and western blotting.


Phosphate uptake experiments and growth assays: In all experiments the growth media did not contain sugar, and plants were grown in sterile culture at 22° C. under 150-200 pE of continuous light. Unless otherwise noted, a standard 0.8% agar medium (Becton Dickenson, Cockeysville, Md.) containing 100 μM phosphate was used for uptake assays (Somerville et al., 1982). Plants used for the phosphate uptake experiments were grown singly in 1 ml of the standard agar medium for 15 days prior to the experiment. On the day of the experiment, 10 μCi32P was applied to the side of the culture dish and allowed to diffuse through the agar. The lids of 95 mm×15 mm tissue' culture dishes (Fisher, Pittsburgh, Pa.) were removed to facilitate transpiration.


After 18 hours, the plants were removed from the medium. The aerial portions of the plant not in contact with the agar were weighed and counted by liquid scintillation. For each plant the entire root system was carefully pulled from the agar and washed in ice cold water prior to scintillation counting. To measure the transport of the products of ATP hydrolysis by the transgenic plants overexpressing apyrase and by wild-type plants, [2,83H]ATP, [α32P]ATP, and [γ32P]ATP (Amersham) were fed to 15-day-old plants in separate treatments. All treatments were analyzed for significance in a T-test (n>46 for all groups, *P<0.05, error bars=s.e.m.).


B. Results


Detection of the pea apyrase in nuclei and in purified plasma membrane: By immunoblot assay, the pea apyrase was found to be associated with nuclei and with purified plasma membranes but not with the cytoplasm (FIG. 1A). The contents of the lanes in FIG. 1A are as follows: Lane 1, cytoplasm; Lane 2, purified plasma membrane; Lane 3, purified nuclei; and Lane 4, pre-immune control of nuclei. Protease treatment destroyed both apyrase activity and antigenicity in outside-out plasma membrane vesicles. After trypsin treatment, the exterior face of the vesicle showed 30% of the ectophosphatase activity of the untreated sample. Endo-phosphatase activities were retained after trypsin treatment, indicating that the digest occurred exclusively on the exterior face of the membrane. These data indicated that the ectoapyrase was in fact being expressed in the extracellular matrix (ECM).


Enhanced Growth of Plants Over-Expressing Apyrase: Three of the four transgenic plant lines constitutively expressed psNTP9 under the control of the cauliflower mosaic virus 35S promoter and over an 18 hour period showed two to five times as much phosphate accumulation in shoots as wild type (FIG. 1B); Top, the total phosphate accumulated in the shoots of three independent transformants in an 18 hour 32 p uptake assay at 2 mM phosphate; Bottom, a corresponding immunoblot performed on equal amounts of protein isolated from the ECM of three week-old wild-type Arabidopsis thaliana and the psNTP9 transgenics. Apyrase expressing plants also showed four times as much phosphatase activity in the extracellular matrix as the wild-type (FIG. 1 C). (Note, OE 1 in the FIG. stands for over-expression 1 transgenic line).


Transgenic plants preferentially transport the gamma phosphate of ATP: In order to address whether over-expression of ectoapyrase was stimulating the adenosine salvage pathway, the intracellular uptake of adenosine was measured both in the presence and absence of the overexpression of apyrase. The inability of apyrase to translocate either extracellular AMP or adenosine was demonstrated by the low level of radiolabel accumulated in the transgenic plants fed [2,83H]ATP and [a32P]ATP (FIG. 2). The complete dephosphorylation of [2,83H]ATP would result in a radiolabelled adenosine molecule while the complete dephosphorylation of [a32P]ATP would result in a non-labeled adenosine label. FIG. 2A illustrates that plants overexpressing apyrase did not translocate radiolabelled adenosine (or byproducts of the dephosphorylation of [2,83H]ATP) any more efficiently than plants not overexpressing apyrase (wild-type plants). FIG. 2B illustrates that plants overexpressing apyrase did not translocate AMP (or the byproducts of the dephosphorylated [a32P]ATP) any more efficiently than wildtype plants. In comparison, feeding experiments where the y phosphate was labeled, the transgenics accumulated three times the amount of labeled phosphate as the wild-type (FIG. 2C). These data show that the over-expression of apyrase does not induce an increase in the uptake of adenosine and therefore its over-expression does not act to stimulate the adenosine salvage pathway.


Example 4
EctoPhosphatase is Involved in Drug Resistance in Yeast and Plants

A. Materials and Methods


Expression of AtPGP-1 in yeast: The AtPGP-1 cDNA (Arabidopsis thaliana MDR gene, accession #X61370) was subcloned into pVT101 downstream of the ADH promoter to create the AtPGP-1/pVT101 construct. AtPGP-1/pVT101 and pVT101 were transformed into Saccharomyces cerevisiae INVSCI (genotype: MATa, his3-Δ1, leu2, trpl-289, ura3-52) and YMR4 (genotype: MATαhis3-11,15, leu2-3, 112ura3Δ5, can Res pho5, 3::ura3A1) by a PEG lithium acetate procedure (Eble, 1992) and selected on uracil dropout medium.


Yeast Growth: Yeast were grown at 30° C. under conditions of constant selection for uracil auxotrophy. YNB (Bio101, Vista, Calif.) supplemented with CSM (uracil dropout) and 2% glucose was used to grow strains having pVT101 constructs. Cycloheximide (Sigma Chemical, St. Louis, Mo.) was added to liquid media or spread on solid media to achieve a final concentration of 500 ng/ml. Nigencm (Sigma Chemical, St. Louis, Mo.) was added to liquid media or spread on solid media to achieve a final concentration of 25 μg/ml. Yeast strains used in cycloheximide selection assays were always propagated in the presence of the cycloheximide on plates and then streaked onto new plates containing drug or no drug, such that induced resistance existed in each strain at the time of the start of the assay. For selection assays on plates, single colonies were streaked; for selection in liquid media 0.01 ml of saturated culture was added to fresh media containing the drug. The plates shown in figures were grown for 3-5 days before photographs were taken. Yeast selection assays in liquid media were quantitated by turbidity as measured by absorbance at OD600.


Expression of apyrase and AtPGP-1 in plants: The expression of apyrase in plants is as described above in Example 3. Similar methods were employed to express AtPGP-1 in Arabidopsis thaliana plants with the following modifications. The AtPGP-1 coding region was subcloned into a pBIN vector lacking the GUS gene as described in Sidler et al. (1998). This plasmid was then transformed into A. tumefaciens as described above, which was used to infect root calli to produce transgenic plants expressing AtPGP-1.


Plant growth: Arabidopsis thaliana seeds were sown in a solid germination media containing MS salt, 2% sucrose, 0.8% agar, and vitamins (Valvekens et al., 1992). For selection assays, cycloheximide was spread on the media to achieve a final concentration of 250 ng/ml. Plant growth was measured by germination percentage after 6-30 days.


B. Results


Effect of over-expression of AtPGP-1 in yeast: When a yeast mutant, YNIR4, which is deficient in two major extracellular phosphatases and tends to accumulate ATP extracellularly, was grown in a potent cellular toxin, cycloheximide, it did not grow whereas a wild-type yeast strain, INVSCI, did grow in the presence of cycloheximide (FIG. 3A). Surprisingly, expression of the plant multidrug resistance (MDR) gene, AtPGP-1, enabled the yeast mutant to grow in the toxin (FIG. 3B and FIG. 5A). The presence of AtPGP-1 in the wild-type yeast did not have any effect when grown in the presence of cycloheximide (FIG. 3B). The same result was obtained when the yeast strains were cultured in nigericin (FIG. 3C, 3D, FIG. 5B, 5C). In FIGS. 3C and 3D, starting from the top of the dish clockwise, the cells are as follows: INVSCI (wild-type) overexpressing AtPGP-1, YNM4 containing the vector alone, YMR4 overexpressing AtPGP-1, and INVSCI containing the vector alone. When grown without drug, all the cells grow (FIG. 3C). However, when grown in drug, only the YMR4 containing vector alone shows reduced growth. The survival of the AtPGP-1 transformed strains was due to the ability of the NIDR1 channel to efflux the toxin, hence lowering the actual cellular concentration of the poison cycloheximide. The sensitivity of the untransformed mutant to the drug is likely due to a loss of the ATP gradient below a point at which endogenous transporters, similar to AtPGP-1 can function.


Effect of over-expression of AtPGP-1 in plants: The over-expression of AtPGP-1 was able to confer resistance to cycloheximide in plants (FIGS. 4A and 6) and to the cytokinin, N6-(2isopentenyl)adenine (21P) (FIG. 4B). These results had not been observed previously and in fact, the prior art actually teaches away from this finding suggesting that over-expression of plant AtPGP-1 is not involved in drug resistance (Sidler. et al., 1998). Therefore, this result was particularly unexpected in plants. Additionally, since Arabidopsis plants overexpressing AtPGP-1 are able to grow in both cycloheximide and cytokinin, this suggests that the conference of drug resistance by AtPGP-1 is likely to be seen with other chemicals as well and is not an isolated phenomenon.


Effect of over-expression of apyrase on drug resistance in plants: Another unexpected result was obtained when the plant apyrase gene was over-expressed in plants. Over-expression of apyrase in plants resulted in the conference of resistance to cycloheximide (FIGS. 4A and 6). The same result was obtained when the plants were grown in the presence of a cytokinin, N6-(2isopentenyl)adenine (FIG. 4B). In fact, over-expression of apyrase is surprisingly able to raise the germination rate above the level obtained by the over-expression of the MDR gene AtPGP-1 (FIGS. 4A, 4B and 6). Just as under-expression of phosphatase activity in a yeast mutant lacking two potent extracellular phosphatases diminished its resistance to cycloheximide (FIG. 3A), over-expression of a powerful extracellular ATP phosphatase in plants bolstered resistance. The fact that higher resistance was found in plants genetically manipulated only with respect to phosphatase over-expression and not MDR1, indicates that there likely exists other ATP-symporters used in detoxification in addition to MDR1. Minimally, the stronger ATP gradient set up by apyrase in the transgenic plants affects the kinetics of the wild-type MDRI.


Example 5
ATP Efflux in Yeast and Plants Overexpressing AtPGP-1

A. Materials and Methods


ATP collection: Yeast cells used in the luciferase assays were grown for two days and then transferred to Lsh media at the time of the assay. From this time forward, the cells were kept at room temperature on a rotator. Every hour a 1 ml aliquot was taken, the cells in the aliquot were counted on a hemocytometer, a methylene blue viability assay was performed (Boyum and Guidotti, 1997), the cells were centrifuged, and the supernatant was stored in liquid nitrogen until all the aliquots were collected. For luciferase assays involving plants, Arabidopsis thaliana plants were grown in sterile culture at 22° C. under 150-200 pE of continuous light for at least 15 days. Foliar ATP was collected by placing a single 30 pl drop of luciferase buffer (Analytical Luminescence Laboratory, Cockeysville, Md.) on a leaf and, without making direct physical contact with the plant, the droplet was immediately collected and snap frozen. For each leaf, the area was approximated as an integrated area of a 2-D image of the leaf using NIH 1.52 software (Shareware, NIH).


Luminometry: Samples were reconstituted to a 100 pl final volume in Firelight™ buffer (Analytical Luminescence Laboratory, Cockeysville, Md.). After the buffer was added, all samples were kept on ice. ATP standards were reconstituted in 100 μl of Firelight™ buffer and the standards and sample were loaded into a 96-well plate and read on an automated Dynex Technologies Model MLX luminometer (Dynex Technologies, Chantilly, Va.). Samples were processed with the addition of 50 μl of Firelight™ enzyme (Analytical Luminescence Laboratory, Cockeysville, Md.) followed by a reading delay of 1.0 second and an integration time of 10 seconds. Output was taken as an average for the integration time and then averaged for multiple samples. The sample handling time was less than 2 hours.


Pulse Chase experiments: Yeast were grown to saturation in liquid medium, as described above, centrifuged, and resuspended in fresh medium containing 1 μCi/ml 3H-adenosine (Amersham, Arlington Heights, Ill.). The cells were rotated at room temperature for 20 minutes to allow adenosine uptake. After 20 minutes the cells were centrifuged. The pellet was washed twice in ice cold medium, resuspended in culture medium at room temperature, divided equally between five types (five per cell line), and placed on a rotator. Every ten minutes a separate tube from each cell line was centrifuged and the pellet and supernatant were placed in separate scintillation vials. The efflux activity was expressed as the ratio of counts in the supernatant to counts in the pellet.


B. Results


The ATP effluxed by the plant MDR1, AtPGP-1, over-expressed in yeast: In wild-type cells there is a steady-state level of ATP in the extracellular fluid, which is to say that the ATP outside the cells is rapidly degraded by phosphatases and does not accumulate over time (FIG. 7). However, the expression of the AtPGP-1 doubled this steady-state level (FIG. 8). If the yeast mutant, YMR4, which is deficient in extracellular phosphatase activity, is analyzed, there was a noticeable accumulation of ATP in the extracellular fluid compared to a control mutant transformed with empty plasmid pVT101 (FIG. 9). In addition to ATP measurements based on luminometry performed on a kinetic time-scale of hours, an earlier differential ATP efflux in MDRI expressing cells by pulse chase experiments was demonstrated (FIG. 10). Furthermore, Arabidopsis thaliana plants from two independently transformed lines, that constitutively express the AtPGP-1 protein, showed a significant accumulation of ATP on their leaf surfaces (FIG. 11). Taken together, these data demonstrate the absolute ability of plant MDRI, AtPGP1, to transport ATP from inside the cell to the outside. Moreover, these data show that ATP efflux channels and phosphatases both have roles in the steady-state level of ATP outside of the cell. This is the first demonstration of the importance of extracellular ATP steady-state levels, and the importance of an ATP gradient across biological membranes in the modulation of drug resistance.


Example 6
A Two-Component System is Found in Arabidopsis Plants

A. Materials and Methods


Plant Growth: Arabidopsis seeds were sown in a solid germination media containing MS salts (Sigma Chemical, St. Louis, Mo.), 2% sucrose, 0.8% agar, and vitamins (Valvekens et al., 1992). For selection assays, one of the following, or a combination of both, was added to media (cooled to less than 50° C. before adding) immediately prior to pouring into plates: cycloheximide at a final concentration of 500 ng/ml; α,β-methyleneadenosine 5′-diphosphate at a final concentration of 1 mM. Plant growth was measured by germination percentage after 10-20 days.


All other materials and methods were discussed above in Example 4.


B. Results


Effects of phosphatase inhibitor on plants overexpressing AtPGP-1: FIG. 12 shows that when wild-type and AtPGP-1 overexpressing (MDR OE) Arabidopsis thaliana plants were either treated with nothing (lane 1), cycloheximide (lane 2), a,(3-methyleneadenosine 5′-diphosphate (phosphatase inhibitor) (lane 3), or cycloheximide and phosphatase inhibitor (lane 4), both the wild-type and the AtPGP-1 overexpressing plants were affected similarly by the presence of phosphatase inhibitor. While the AtPGP-1 overexpressing plants grew significantly better in the presence of cycloheximide alone with a 50% germination rate for the AtPGP-1 overexpressing plants and a 2% germination rate for the wild-type plants, similar germination rates were seen for both the AtPGP-1 overexpressing and wild-type plants in the presence of either phosphatase inhibitor alone (83% and 90% germination respectively) or cycloheximide plus phosphatase inhibitor (no germination at all). The addition of phosphatase inhibitor surprisingly destroys the ability of the AtPGP-expressing plants to grow in the presence of cycloheximide. These data suggest that phosphatases are involved in the conference of drug resistance in plants and that there is a two-component system similar to that demonstrated in yeast in Example 4 and 5 above in which an MDR-like protein and an ATP-gradient-maintaining ectophosphatase are important in modulating drug resistance.


Example 7
The ATP Gradient Directly Effects Drug Resistance in Cells

A. Materials and Methods


Cell lines: Cell lines were the same as those described above in Example 4 and 5. YMR4 MDRI is the phosphatase mutant yeast strain overexpressing AtPGP-1; YMR4 pVT011 contains vector alone; INVSC MDRI is the wild-type yeast strain overexpressing AtPGP-1; and INVSC pVT101 contains vector alone.


Selection in drug: To create drug resistant yeast strains, all four cell lines were grown up in the presence of 500 ng/ml of cycloheximide, and transferred to other cycloheximide containing plates after a period of four to six days. This transfer of cell lines and subculturing continued such that the yeast cells grew in the presence of cycloheximide for a period of at least a month. Cells cultured in media alone: To create cell lines that had not been preselected for their ability to grow in drug, yeast strains were grown on plates containing YNB (Bio101, Vista, Calif.) without uracil (-URA) to maintain the presence of the vector (which supplies URA) without any drugs added.


Growth of cells in suspension for ATP and drug selection experiments: Cells were transferred into 5 ml YNB-URA liquid media for turbidity measurements. All cell lines (both non-drug selected and drug-selected) were grown in media with the addition of either nothing, 500 ng/ml cycloheximide, 100 mM ATP, or 500 ng/ml cycloheximide and 100 mM ATP. Turbidity readings were taken after 48 hours.


Growth of cell lines in suspension for salvage pathway experiments: All cell lines were grown in liquid media either containing drug (for the drug selected lines) or not containing drug (for the non-drug selected lines). When the cultures reached a turbidity of 1.00 as measured at a wavelength of 600 in a spectrophotometer (OD600=1.00), 10 μl of each culture was then removed and placed in either media with nothing added, 3 mM potassium phosphate; 3 mM adenosine; 9 mM potassium phosphate and 3 mM adenosine (for controls); potassium phosphate and cycloheximide; adenosine and cycloheximide; adenosine, cycloheximide, and potassium phosphate. Cell cultures were further grown for 72 hours, and their turbidity was determined by OD600 readings on a spectrophotometer.


Growth of cell lines for nigericin experiments: Drug selected lines were removed from cycloheximide containing plates and placed in 5 ml liquid media containing 5 ng/ml cycloheximide. Cell cultures were allowed to grow until they reached an OD600 reading of 1.00, and then 10 μl from each culture was removed and transferred to culture tubes containing 5 ml of liquid media and 25 pg/ml nigericin. OD600 readings were recorded daily for a period of up to 72 hours to determine growth.


B. Results


An ATP gradient is critical in MDR: The importance of the ATP gradient in MDR in yeast cells was demonstrated by showing that the growth of cells which were previously grown in drug and had developed resistance to the drug, were not able to grow in high levels of ATP unless they were overexpressing AtPGP-1 (FIG. 13). Cells which had not been previously selected in drug were able to grow in the presence of high levels of ATP (FIG. 13). These data emphasize that the loss of an ATP gradient is previously resistant cell lines abolishes resistance. This result is new to the understanding of MDR and has led to vast insight into the understanding of the mechanism by which MDR-ABC transporters confer resistance to cells and to methods to modulate such resistance. Moreover, when cells were grown in high levels of ATP and drug (cycloheximide), even the cell lines which had previously showed resistance to drug were unable to grow in the presence of drug and ATP. These data indicate that when the ATP gradient across biological membranes is destroyed (by the presence of high extracellular levels of ATP), efflux a of drugs cannot be achieved and therefore, drug resistance is abolished. In summary, the multidrug resistance channel is not functional without an ATP gradient.


The drug resistance is not due to an adenosine salvage pathway: In order to address whether the involvement of a nucleotide salvage pathway was responsible for the results of the present invention, yeast cells were cultured in the presence of extracellular adenosine and extracellular phosphate. The acid phosphatase yeast mutant, YMR4, was selected because its decreased ectophosphatase activity makes it an ideal candidate for studying the effect of extracellular nucleotides on growth. If an adenosine salvage pathway were involved, then the presence of extracellular adenosine or possibly phosphate should help cells recoup the intracellular ATP losses due to ATP/drug efflux and should help cells grow in the presence of drug whether or not the cells were overexpressing AtPGP-1. In contrast, however, the addition of adenosine or phosphate to the media did not enhance resistance to the cells (FIG. 14). In fact, cells overexpressing AtPGP-1 grew best in drug alone, with the addition of adenosine and/or phosphate being slightly inhibitory. Furthermore, cells which did not express AtPGP-1 were unable to grow in drug regardless of the presence of adenosine and/or phosphate. These data suggest that an adenosine salvage pathway is not the principal mechanism at work in the present invention.


Example 8
High Throughput Screen for Isolating Apyrase Inhibitors

A. Materials and Methods


Small Molecule Library: A small molecule library (DIVERSet format F), which was specifically constructed to maximize structural diversity in a relatively small library (9600 compounds), was obtained from ChemBridge Corporation (San Diego, Calif.). The small molecules (supplied in 0.1 mg dehydrated aliquots) were dissolved in DMSO, transferred to a 96 well plate, and tested for their ability to inhibit apyrase activity.


The assay: A stringent screen to test the ability of small molecules to disrupt the ATPase activity of the apyrase enzyme was developed based on phosphate-mobylate complexation. The assay was a modification of a phospholipase assay developed by Hergenrother et al. (1997): Under normal conditions, the apyrase enzyme liberates phosphate from ATP present in the reaction. The liberated phosphate quickly forms a complex upon addition of a small amount of acidified molybdate and ascorbate allowing for the production of a very dark blue color (the less phosphate liberated, the less blue color). Control reactions were performed with heat inactivated apyrase enzyme. Color intensity was detected on an Alpha Imager 2000 with AlphaEase™ software (Alpha Innotech, San Leandro, Calif.). Color changes were also evident by the naked eye. A Biomek 2000 robot (Beckman, Fullerton, Calif.) was used for screening the 9600 samples.


To each well of the 96 well plates containing a small molecule from the library, 100 pI of reaction buffer (60 mM HEPES, 3 MM MgCl2, 3 mM CaCl2, 3 mM ATP pH 7.0) was added. The apyrase (potato apyrase grade VI, Sigma Chemical, St. Louis, Mo.) enzyme (0.1 units) was added in a 5 pI volume and the reaction was allowed to proceed at room temperature for 60 minutes.


Three buffers were used to visualize activity: Buffer A: 2% Ammonium molybdate in water Buffer B: 1 I% Ascorbic acid in 37.5% aqueous TCA. Buffer C: 2% trisodium citrate, 2% acetic acid.


Immediately before developing the assay, buffers A and B were mixed in a 1:1 5 ratio. 50 pl of A:B was added to each well. The 96 well plate was then vibrated on a table surface to mix the solution. The deep blue color developed after approximately 2 minutes. After 2 minutes, 50 p.l of buffer C was added to each well and the blue color became darker, increasing the sensitivity of the assay. The color intensified for up to one hour with no accompanying color change in the control wells containing heat inactivated apyrase enzyme. The color intensity for a single plate was measured on an Alpha Imager 2000 with AlphaEase™ software (Alpha Innotech, San Leandro, Calif.).


B. Results:


Nineteen positives were identified from the 9600 compound DIVERSet library. Dose response assays revealed that fourteen showed weak inhibition, two showed medium inhibition (Formulas N and V), and three showed relatively strong inhibition (Formulas I, II and III).


All of the compositions and methods disclosed and claimed herein can be made and executed without undue experimentation in light of the present disclosure. While the compositions and methods of this invention have been described in terms of preferred embodiments, it will be apparent to those of skill in the art that variations may be applied to the compositions and methods and in the steps or in the sequence of steps of the method described herein without departing from the concept, spirit and scope of the invention. More specifically, it will be apparent that certain agents which are both chemically and physiologically related may be substituted for the agents described herein while the same or similar results would be achieved. All such similar substitutes and modifications apparent to those skilled in the art are deemed to be within the spirit, scope and concept of the invention as defined by the appended claims.


REFERENCES

The following references, to the extent that they provide exemplary procedural or other details supplementary to those set forth herein, are specifically incorporated herein by reference.

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Claims
  • 1. A cytotoxic composition comprising an ectophosphatase inhibitor and a cytotoxic agent set forth in Table 1.
  • 2. The cytotoxic composition of claim 1, wherein the cytotoxic agent is selectively cytotoxic.
  • 3. The cytotoxic composition of claim 1, further defined as a herbicidal composition and wherein the cytotoxic agent is a herbicide.
  • 4. The cytotoxic composition of claim 1, further defined as an insecticidal composition and wherein the cytotoxic agent is an insecticide.
  • 5. The cytotoxic composition of claim 1, further defined as a fungicidal composition and wherein the cytotoxic agent is a fungicide.
  • 6. The cytotoxic composition of claim 1, further defined as an antibiotic composition and wherein the cytotoxic agent is an antibiotic.
  • 7. The antibiotic composition of claim 6, wherein the antibiotic is from a class selected from the group consisting of Beta-lactam, Semisynthetic penicillin, Clavulanic Acid, Monobactams, Carboxypenems, Aminoglycosides, Glycopeptides, Lincomycins, Macrolides, Polyenes, Rifamycins, Tetracyclines, Semisynthetic, tetracycline and Chloramphenicol.
  • 8. The cytotoxic composition of claim 1, wherein the ectophosphatase inhibitor is selected from the group consisting of the compounds of formulae I-XX.
  • 9. A plant growth regulator composition comprising an ectophosphatase inhibitor and a plant growth regulator agent set forth in Table 1.
  • 10. The plant growth regulator composition of claim 9, wherein the ectophosphatase inhibitor is selected from the group consisting of the compounds of formulae I-XX.
  • 11. A chemotherapeutic composition comprising an ectophosphatase inhibitory compound and a chemotherapeutic agent.
  • 12. The chemotherapeutic composition of claim 11, wherein the chemotherapeutic agent is a chemotherapeutic agent set forth in Table 3.
  • 13. The chemotherapeutic composition of claim 11, wherein the ectophosphatase inhibitor is selected from the group consisting of the compounds of formulae I-XX.
  • 14. A method of killing or inhibiting the growth of a plant, comprising contacting said plant with an effective amount of the composition of claim 3.
  • 15. The method of claim 14, wherein said plant is a monocotyledonous plant.
  • 16. The method of claim 14, wherein the plant is a dicotyledonous plant.
  • 17. A method of killing or inhibiting the growth of a tumor cell, comprising contacting said tumor cell with an effective amount of the composition of claim 11.
  • 18. The method of claim 17, wherein contacting comprises administering said composition of claim 11 to a patient in need thereof, wherein the patient comprises the tumor cell.
  • 19. A method of killing or inhibiting the growth of an insect, comprising contacting said insect with the composition of claim 4.
  • 20. A method of killing or inhibiting the growth of a fungal cell, comprising contacting said cell with the composition of claim 5.
  • 21. A method of killing or inhibiting the growth of a bacterial cell, comprising contacting said cell with the composition of claim 6.
  • 22. A method of increasing the effectiveness of a cytotoxic agent, comprising admixing said cytotoxic agent with an ectophosphatase inhibitor, wherein the cytotoxic agent is selected from the group set forth in Table 1.
  • 23. The method of claim 22, wherein the cytotoxic agent is further defined as a herbicide.
  • 24. The method of claim 22, wherein the cytotoxic agent is further defined as an insecticide, fungicide, or antibiotic.
  • 25-26. (canceled)
  • 27. The method of claim 24, wherein the antibiotic is from a class selected from the group consisting of Beta-lactam, Semisynthetic penicillin, Clavulanic Acid, Monobactams, Carboxypenems, Aminoglycosides, Glycopeptides, Lincomycins, Macrolides, Polyenes, Rifamycins, Tetracyclines, Semisynthetic, tetracycline and Chloramphenicol.
  • 28. The method of claim 22, wherein the ectophosphatase inhibitor is selected from the group consisting of the compounds of formulae I-XX.
  • 29. A method of increasing the effectiveness of a chemotherapeutic agent, comprising admixing said chemotherapeutic agent with an ectophosphatase inhibitor, wherein the chemotherapeutic agent is selected from the group set forth in Table 3.
  • 30. The method of claim 29, wherein the ectophosphatase inhibitor is selected from the group consisting of the compounds of formulae I-XX.
PCT Information
Filing Document Filing Date Country Kind 371c Date
PCT/US03/32667 10/16/2003 WO 1/23/2006
Provisional Applications (1)
Number Date Country
60418803 Oct 2002 US