TREA

METHODS AND SYSTEMS FOR DIAGNOSIS, CLASSIFICATION, AND TREATMENT OF SMALL CELL LUNG CANCER AND OTHER HIGH-GRADE NEUROENDOCRINE CARCINOMAS

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Information

  • Patent Application
  • 20240150848
  • Publication Number
    20240150848
  • Date Filed
    March 03, 2022
    2 years ago
  • Date Published
    May 09, 2024
    27 days ago
Information
Abstract
Aspects of the disclosure are directed to methods and systems for diagnosis, classification, and treatment of small cell lung cancer and high grade neuroendocrine carcinomas. Certain aspects comprise detection and analysis of tumor DNA methylation. Included in the disclosure are methods for identifying a subject as having a particular small cell lung cancer subtype based on DNA N methylation analysis, as well as methods and compositions for treatment of a subject based on subtype classification.
Description
BACKGROUND
I. Field of the Invention

Aspects of this invention relate to at least the fields of cancer biology and medicine.


II. Background

For patients with small cell lung cancer (SCLC) or other high-grade neuroendocrine carcinomas (HGNEC), there are currently no validated biomarkers in routine use for classifying the disease into therapeutically relevant subgroups and predicting response to different therapies; nor are there blood-based biomarkers for diagnosing SCLC or HGNEC and distinguishing it from other types of cancers. Unlike non-small cell lung cancer (NSCLC), for which there are well established genomic markers (e.g. EGFR mutation) and proteomic markers (e.g. PD-L1) for selecting treatments, there are currently no similar markers in SCLC or HGNEC. One challenge in diagnosis, treatment, and analysis of SCLC and HGNEC is that there is usually limited tumor tissue available for analysis. The identification of biomarkers that can help classify SCLC and HGNEC, predict response to therapy, and distinguish it from other tumor types therefore represents a fundamental unmet need for SCLC, particularly if such analysis could be performed using minimal tissue or other sources more readily available such as blood.


SUMMARY

The present disclosure fulfills certain needs in the fields of cancer biology and medicine by providing methods and compositions for diagnosis, classification, and treatment of SCLC and SCLC subtypes. Embodiments are directed to compositions and methods for identifying a subject as having SCLC-A, SCLC-N, SCLC-P. or SCLC-I based on analysis of methylation sites from tumor DNA from the subject. Also disclosed are methods for treatment of a subject having SCLC-A, SCLC-N, SCLC-P, or SCLC-I.


Embodiments of the present disclosure include methods for treating a subject for SCLC, methods for diagnosing a subject with SCLC, methods for identifying a subject with cancer as having SCLC, methods for classifying SCLC of a subject, methods for identifying a subject as having SCLC-A, methods for identifying a subject as having SCLC-N, methods for identifying a subject as having SCLC-P, methods for identifying a subject as having SCLC-I, methods for analysis of tumor methylation, methods for prognosing a subject with SCLC, methods for selecting a treatment for a subject with SCLC, and kits for nucleic acid analysis. Methods of the present disclosure can include at least 1, 2, 3, 4, 5, or more of the following steps: obtaining a biological sample from a subject, obtaining tumor DNA from a subject, classifying a subject as having SCLC-A, classifying a subject as having SCLC-N, classifying a subject as having SCLC-P, classifying a subject as having SCLC-I, determining a methylation status of a methylation site, analyzing tumor DNA from a subject, diagnosing a subject for SCLC, treating a subject for SCLC, administering a BCL2 inhibitor to a subject, administering a DLL3-targeted therapy to a subject, administering an AURK inhibitor to a subject, administering a platinum-based chemotherapeutic agent to a subject, administering a PARP inhibitor to a subject, administering an anti-metabolite to a subject, administering a nucleoside analog to a subject, administering an immunotherapy to a subject, administering a chemotherapy to a subject, and administering a radiotherapy to a subject. One or more of the following steps may be included from embodiments of the disclosure.


Embodiments of the disclosure are directed to a method of treating a subject for small cell lung cancer (SCLC), the method comprising administering a BCL2 inhibitor or a DLL3-targeted therapy to a subject determined, from analysis of tumor DNA from the subject, to have differential methylation at two or more methylation sites selected from the methylation sites of Table 2, Table 7, Table 15, Table 20, and Table 27 compared to a reference or control sample. In some embodiments, the two or more methylation sites are at least or at most 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 100, 150, or 200 methylation sites (or any range or value derivable therein) selected from the methyation sites of Table 2, Table 7, Table 15, Table 20, and Table 27, or more. In some embodiments, the two or more methylation sites are at least or at most 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, or 20 (or any range derivable therein) of the methylation sites of Table 2, or more. In some embodiments, the two or more methylation sites are at least or at most 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, or 20 (or any range derivable therein) of the methylation sites of Table 7, or more. In some embodiments, the two or more methylation sites are at least or at most 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, or 20 (or any range derivable therein) of the methylation sites of Table 15, or more. In some embodiments, the two or more methylation sites are at least or at most 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, or 20 (or any range derivable therein) of the methylation sites of Table 20, or more. In some embodiments, the two or more methylation sites are at least or at most 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, or 20 (or any range derivable therein) of the methylation sites of Table 27, or more. In some embodiments, the method comprises administering the BCL2 inhibitor to the subject. In some embodiments, the BCL2 inhibitor is ABT-737 or navitoclax. In some embodiments, the method comprises administering the DLL3-targeted therapy to the subject. In some embodiments, the DLL3-targeted therapeutic comprises an anti-DLL3 antibody or fragment thereof. In some embodiments, the anti-DLL3 antibody or fragment thereof is rovalpituzumab. In some embodiments, the DLL3-targeted therapeutic is an antibody-drug conjugate. In some embodiments, the antibody-drug conjugate is rovalpituzumab tesirine. In some embodiments, the DLL3-targeted therapeutic is a DLL3-targeted cellular therapy. A DLL3-targeted cellular therapy can include any cell-based therapy for targeting DLL3. In some embodiments, the DLL3-targeted cellular therapy is a DLL3-targeted chimeric antigen receptor (CAR) T-cell. In some embodiments, the DLL3-targeted cellular therapy is a DLL3-targeted CAR NK cell. In some embodiments, the subject was determined to have SCLC-A based on the analysis of the tumor DNA. It is specifically contemplated that 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 100, 150, or 200 methylation sites (or any range derivable therein), or more, selected from the methyation sites of Table 2, Table 7, Table 15, Table 20, and Table 27, may be excluded in embodiments described herein.


Embodiments of the disclosure are directed to a method of treating a subject for SCLC, the method comprising administering an AURK inhibitor to a subject determined, from analysis of tumor DNA from the subject, to have differential methylation at two or more methylation sites selected from the methylation sites of Table 3, Table 8, Table 16, Table 21, and Table 28 compared to a reference or control sample. In some embodiments, the two or more methylation sites are at least or at most 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 100, 150, or 200 methylation sites (or any range or value derivable therein) selected from the methyation sites of Table 3, Table 8, Table 16, Table 21, and Table 28. In some embodiments, the two or more methylation sites are at least or at most 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, or 20 (or any range derivable therein) of the methylation sites of Table 3, or more. In some embodiments, the two or more methylation sites are at least or at most 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, or 20 (or any range derivable therein) of the methylation sites of Table 8, or more. In some embodiments, the two or more methylation sites are at least or at most 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, or 20 (or any range derivable therein) of the methylation sites of Table 16, or more. In some embodiments, the two or more methylation sites are at least or at most 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, or 20 (or any range derivable therein) of the methylation sites of Table 21, or more. In some embodiments, the two or more methylation sites are at least or at most 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, or 20 (or any range derivable therein) of the methylation sites of Table 28, or more. In some embodiments, the AURK inhibitor is CYC-116, alisertib, or AS-703569. In some embodiments, the subject was determined to have SCLC-N based on the analysis of the tumor DNA. It is specifically contemplated that 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 100, 150, or 200 methylation sites (or any range derivable therein), or more, selected from the methyation sites of Table 3, Table 8, Table 16, Table 21, and Table 28, may be excluded in embodiments described herein.


Embodiments of the disclosure are directed to a method of treating a subject for SCLC, the method comprising administering a platinum-based chemotherapeutic agent, a PARP inhibitor, an anti-metabolite, or a nucleoside analog to a subject determined, from analysis of tumor DNA from the subject, to have differential methylation at two or more methylation sites selected from the methylation sites of Table 4, Table 9, Table 17, Table 22, and Table 29 compared to a reference or control sample. In some embodiments, the two or more methylation sites are at least or at most 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 100, 150, or 200 methylation sites (or any range or value derivable therein) selected from the methyation sites of Table 4, Table 9, Table 17, Table 22, and Table 29, or more. In some embodiments, the two or more methylation sites are at least or at most 2, 3, 4, 5, 6, 7, 8, 9, 10, 15, or 20 (or any range derivable therein) of the methylation sites of Table 4, or more. In some embodiments, the two or more methylation sites are at least or at most 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, or 20 (or any range derivable therein) of the methylation sites of Table 9, or more. In some embodiments, the two or more methylation sites are at least or at most 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, or 20 (or any range derivable therein) of the methylation sites of Table 17, or more. In some embodiments, the two or more methylation sites are at least or at most 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, or 20 (or any range derivable therein) of the methylation sites of Table 22, or more. In some embodiments, the two or more methylation sites are at least or at most 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, or 20 (or any range derivable therein) of the methylation sites of Table 29, or more. In some embodiments, the method comprises administering to the subject the platinum-containing chemotherapeutic agent. In some embodiments, the platinum-containing chemotherapeutic agent is cisplatin, carboplatin, oxaliplatin, nedaplatin, picoplatin, or satraplatin. In some embodiments, the method comprises administering to the subject the PARP inhibitor. In some embodiments, the PARP inhibitor is talazoparib, olaparib, niraparib, AZD-2461, or rucaparib. In some embodiments, the method comprises administering to the subject the anti-metabolite. In some embodiments, the anti-metabolite is pemetrexed, methotrexate, or pralatrexate. In some embodiments, the method comprises administering to the subject the nucleoside analog. In some embodiments, the nucleoside analog is floxuridine, cytarabine, clofarabine, or fludarabine. In some embodiments, the subject was determined to have SCLC-P based on the analysis of the tumor DNA. It is specifically contemplated that 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 100, 150, or 200 methylation sites (or any range derivable therein), or more, selected from the methyation sites of Table 4, Table 9, Table 17, Table 22, and Table 29, may be excluded in embodiments described herein.


Embodiments of the disclosure are directed to a method of treating a subject for SCLC, the method comprising administering an immunotherapy to a subject determined, from analysis of tumor DNA from the subject, to have differential methylation at two or more methylation sites selected from the methylation sites of Table 5. Table 10, Table 18, Table 23, and Table 30 compared to a reference or control sample. In some embodiments, the two or more methylation sites are at least or at most 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 100, 150, or 200 methylation sites (or any range or value derivable therein) selected from the methyation sites of Table 5. Table 10, Table 18, Table 23, and Table 30, or more. In some embodiments, the two or more methylation sites are at least or at most 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, or 20 (or any range derivable therein) of the methylation sites of Table 5, or more. In some embodiments, the two or more methylation sites are at least or at most 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, or 20 (or any range derivable therein) of the methylation sites of Table 10, or more. In some embodiments, the two or more methylation sites are at least 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, or 20 (or any range derivable therein) of the methylation sites of Table 18, or more. In some embodiments, the two or more methylation sites are at least 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, or 20 (or any range derivable therein) of the methylation sites of Table 23, or more. In some embodiments, the two or more methylation sites are at least 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, or 20 (or any range derivable therein) of the methylation sites of Table 30, or more. In some embodiments, the immunotherapy is an immune checkpoint inhibitor therapy. In some embodiments, the subject was determined to have SCLC-I based on the analysis of the tumor DNA. It is specifically contemplated that 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 100, 150, or 200 methylation sites (or any range derivable therein), or more, selected from the methyation sites of Table 5, Table 10, Table 18, Table 23, and Table 30, may be excluded in embodiments described herein.


In some embodiments, the method further comprises administering to the subject an additional cancer therapy. In some embodiments, the additional cancer therapy comprises chemotherapy, radiotherapy, immunotherapy, or a combination thereof. In some embodiments, the subject was previously treated for SCLC. In some embodiments, the subject was resistant to the previous treatment.


In some embodiments, the subject was further determined, from the analysis of the tumor DNA from the subject, to have differential methylation of one or more methylation sites of Table 13 compared to the reference or control sample. In some embodiments, the reference or control sample is a DNA sample obtained from healthy cells from the subject. In some embodiments, the reference or control sample is a DNA sample obtained from a cell-free sample (e.g., plasma, serum) from a reference subject. In some embodiments, the reference or control sample is a DNA sample obtained from healthy cells from a reference subject. In some embodiments, the reference or control sample is a DNA sample obtained from a cell-free sample (e.g., plasma, serum) from a reference subject.


Embodiments of the disclosure are directed to a method for classifying a subject having SCLC, the method comprising (a) determining, from DNA from the subject, a methylation status of one or more methylation sites selected from the methylation sites of Tables 1-10, 15-18, 20-23, and 27-30; and (b) classifying the subject as having SCLC-A, SCLC-N, SCLC-P, or SCLC-I based on the methylation status of the one or more methylation sites. In some embodiments, the one or more methylation sites are at least 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 100, 150, or 200 of the methylation sites (or more) selected from the methylation sites of Tables 1-10, 15-18, 20-23, and 27-30.


In some embodiments, (b) comprises classifying the subject as having SCLC-A. In some embodiments, the one or more methylation sites are at least 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, or 20 of the methylation sites selected from the methylation sites of Table 2, Table 7, Table 15, Table 20, and Table 27 or more. In some embodiments, the one or more methylation sites are at least 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, or 20 of the methylation sites of Table 2, or more. In some embodiments, the one or more methylation sites are at least 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, or 20 of the methylation sites of Table 7, or more. In some embodiments, the one or more methylation sites are at least 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, or 20 of the methylation sites of Table 15, or more. In some embodiments, the one or more methylation sites are at least 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, or 20 of the methylation sites of Table 20, or more. In some embodiments, the one or more methylation sites are at least 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, or 20 of the methylation sites of Table 27, or more. In some embodiments, the method further comprises administering to the subject a therapeutically effective amount of a BCL2 inhibitor. In some embodiments, the BCL2 inhibitor is ABT-737 or navitoclax. In some embodiments, the method further comprises administering to the subject a therapeutically effective amount of a DLL3-targeted therapeutic. In some embodiments, the DLL3-targeted therapeutic comprises an anti-DLL3 antibody or fragment thereof. In some embodiments, the anti-DLL3 antibody or fragment thereof is rovalpituzumab. In some embodiments, the DLL3-targeted therapeutic is an antibody-drug conjugate. In some embodiments, the antibody-drug conjugate is rovalpituzumab tesirine.


In some embodiments, (b) comprises classifying the subject as having SCLC-N. In some embodiments, the one or more methylation sites are at least 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, or 20 of the methylation sites selected from the methylation sites of Table 3, Table 8, Table 16, Table 21, and Table 28, or more. In some embodiments, the one or more methylation sites are at least 2, 3, 4, 5, 6, 7, 8, 9, 10, 15, or 20 of the methylation sites of Table 3, or more. In some embodiments, the one or more methylation sites are at least 2, 3, 4, 5, 6, 7, 8, 9, 10, 15, or 20 of the methylation sites of Table 8, or more. In some embodiments, the one or more methylation sites are at least 2, 3, 4, 5, 6, 7, 8, 9, 10, 15, or 20 of the methylation sites of Table 16, or more. In some embodiments, the one or more methylation sites are at least 2, 3, 4, 5, 6, 7, 8, 9, 10, 15, or 20 of the methylation sites of Table 21, or more. In some embodiments, the one or more methylation sites are at least 2, 3, 4, 5, 6, 7, 8, 9, 10, 15, or 20 of the methylation sites of Table 28, or more. In some embodiments, the method further comprises administering to the subject a therapeutically effective amount of an AURK inhibitor. In some embodiments, the AURK inhibitor is CYC-116, alisertib, or AS-703569.


In some embodiments, (b) comprises classifying the subject as having SCLC-P. In some embodiments, the one or more methylation sites are at least 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, or 20 of the methylation sites selected from the methylation sites of Table 4, Table 9, Table 17, Table 22, and Table 29, or more. In some embodiments, the one or more methylation sites are at least 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, or 20 of the methylation sites of Table 4, or more. In some embodiments, the one or more methylation sites are at least 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, or 20 of the methylation sites of Table 9, or more. In some embodiments, the one or more methylation sites are at least 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, or 20 of the methylation sites of Table 17, or more. In some embodiments, the one or more methylation sites are at least 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, or 20 of the methylation sites of Table 22, or more. In some embodiments, the one or more methylation sites are at least 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, or 20 of the methylation sites of Table 29, or more. In some embodiments, the method further comprises administering to the subject a therapeutically effective amount of a platinum-containing chemotherapeutic agent. In some embodiments, the platinum-containing chemotherapeutic agent is cisplatin, carboplatin, oxaliplatin, nedaplatin, picoplatin, or satraplatin. In some embodiments, the method further comprises administering to the subject a therapeutically effective amount of a PARP inhibitor. In some embodiments, the PARP inhibitor is talazoparib, olaparib, niraparib, AZD-2461, or rucaparib. In some embodiments, the method further comprises administering to the subject a therapeutically effective amount of an anti-metabolite. In some embodiments, the anti-metabolite is pemetrexed, methotrexate, or pralatrexate. In some embodiments, the method further comprises administering to the subject a therapeutically effective amount of a nucleoside analog. In some embodiments, the nucleoside analog is floxuridine, cytarabine, clofarabine, or fludarabine.


In some embodiments, (b) comprises classifying the subject as having SCLC-I. In some embodiments, the one or more methylation sites are at least 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, or 20 of the methylation sites selected from the methyation sites of Table 5, Table 10, Table 18, Table 23, and Table 30, or more. In some embodiments, the one or more methylation sites are at least 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, or 20 of the methylation sites of Table 5, or more. In some embodiments, the one or more methylation sites are at least 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, or 20 of the methylation sites of Table 10, or more. In some embodiments, the one or more methylation sites are at least 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, or 20 of the methylation sites of Table 18, or more. In some embodiments, the one or more methylation sites are at least 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, or 20 of the methylation sites of Table 23, or more. In some embodiments, the one or more methylation sites are at least 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, or 20 of the methylation sites of Table 30, or more. In some embodiments, the method further comprises administering to the subject a therapeutically effective amount of an immunotherapy. In some embodiments, the immunotherapy is a checkpoint blockade therapy.


In some embodiments, DNA from the subject is obtained from blood or plasma from the subject. In some embodiments, the DNA is circulating tumor DNA (ctDNA). In some embodiments, the DNA is obtained from cancer tissue from the subject.


In some embodiments, the method further comprises determining, from the DNA from the subject, a methylation status of one or more methylation sites of Table 13. In some embodiments, the one or more methylation sites comprise, comprise at least, or comprise at most 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, or 27 of the methylation sites of Table 13.


Embodiments are directed to a method of identifying a subject with cancer as having SCLC, the method comprising (a) determining, from DNA from the subject, a methylation status of one or more methylation sites of Table 13; and (b) identifying the subject as having SCLC based on the methylation status of the two or more methylation sites. In some embodiments, the one or more methylation sites are, are at least, or are at most 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, or 27 of the methylation sites of Table 13.


Embodiments are directed to a method for treating a subject for SCLC comprising administering an SCLC therapy to a subject determined, from analysis of tumor DNA from the subject, to have differential methylation at one or more methylation sites of Table 13 compared to a reference or control sample. In some embodiments, the SCLC therapy comprises chemotherapy, immunotherapy, radiotherapy, or a combination thereof. In some embodiments, the SCLC therapy comprises a platinum-containing chemotherapeutic agent. In some embodiments, the platinum-containing chemotherapeutic agent is cisplatin, carboplatin, oxaliplatin, nedaplatin, picoplatin, or satraplatin.


Further embodiments include use of an SCLC therapy for treatment of a subject having differential methylation at one or more methylation sites of Table 13 compared to a reference or control sample. In some embodiments, the one or more methylation sites are, are at least, or are at most 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, or 27 of the methylation sites of Table 13. In some embodiments, the SCLC therapy comprises a platinum-containing chemotherapeutic agent. In some embodiments, the platinum-containing chemotherapeutic agent is cisplatin, carboplatin, oxaliplatin, nedaplatin, picoplatin, or satraplatin.


Additional aspects of the disclosure include methods for treating a subject for SCLC comprising administering a therapeutically effective amount of HG-5-88-01, ZG-10, BI-2536, Dinaciclib, GW843682X, OTX015, Sinularin, Sunitinib, ULK1 4989, GSK591, or JAK1 8709 to a subject determined, from analysis of tumor DNA from the subject, to have differential methylation at chr4:152172102 (cg06883206), chr1:155177783 (cg02516288), chr17:46804309 (cg16557178), chr14:56604516 (cg16770832), chr17:46804309 (cg16557178), chr7:26192756 (cg14644871), chr9:130659142 (cg03083695), chr1:15272238 (cg11648522), chr14:63872285 (cg02929982), chr8:42132866 (cg05570682), or chr19:47156401 (cg22981158), respectively, compared to a reference or control sample.


Where the present application refers to methods performed on a subject determined, from analysis of tumor DNA from the subject, to have differential methylation, embodiments are also directed to those same methods performed on a subject having that differential methylation. In these embodiments the differential methylation may be determined by analyzing tumor DNA from the subject.


Further embodiments include a method of diagnosing small cell lung cancer (SCLC) in a subject, comprising analyzing tumor DNA from the subject, wherein differential methylation compared to a reference or control sample at one or more methylation sites selected from the methylation sites listed in Tables 2, 3, 4, 5, 7, 8, 9, 10, 15, 16, 17, 18, 20, 21, 22, 23, 27, 28, 29, and/or 30 indicates that the subject has SCLC.


Further embodiments include the use of differential methylation compared to a reference or control sample at one or more methylation sites selected from the methylation sites listed in Tables 2, 3, 4, 5, 7, 8, 9, 10, 15, 16, 17, 18, 20, 21, 22, 23, 27, 28, 29, and/or 30 in a method of diagnosing small cell lung cancer (SCLC) in a subject. In certain embodiments, the use comprises analyzing tumor DNA from the subject, wherein differential methylation compared to a reference or control sample at one or more methylation sites selected from the methylation sites listed in Tables 2, 3, 4, 5, 7, 8, 9, 10, 15, 16, 17, 18, 20, 21, 22, 23, 27, 28, 29, and/or 30 indicates that the subject has SCLC.


Throughout this application, the term “about” is used to indicate that a value includes the inherent variation of error for the measurement or quantitation method.


The use of the word “a” or “an” when used in conjunction with the term “comprising” may mean “one,” but it is also consistent with the meaning of “one or more,” “at least one,” and “one or more than one.”


The phrase “and/or” means “and” or “or”. To illustrate, A. B, and/or C includes: A alone, B alone, C alone, a combination of A and B, a combination of A and C, a combination of B and C. or a combination of A. B, and C. In other words, “and/or” operates as an inclusive or.


The words “comprising” (and any form of comprising, such as “comprise” and “comprises”), “having” (and any form of having, such as “have” and “has”), “including” (and any form of including, such as “includes” and “include”) or “containing” (and any form of containing, such as “contains” and “contain”) are inclusive or open-ended and do not exclude additional, unrecited elements or method steps.


The compositions and methods for their use can “comprise,” “consist essentially of,” or “consist of” any of the ingredients or steps disclosed throughout the specification. Compositions and methods “consisting essentially of” any of the ingredients or steps disclosed limits the scope of the claim to the specified materials or steps which do not materially affect the basic and novel characteristic of the claimed invention. As used in this specification and claim(s), the words “comprising” (and any form of comprising, such as “comprise” and “comprises”), “having” (and any form of having, such as “have” and “has”), “including” (and any form of including, such as “includes” and “include”) or “containing” (and any form of containing, such as “contains” and “contain”) are inclusive or open-ended and do not exclude additional, unrecited elements or method steps. It is contemplated that embodiments described herein in the context of the term “comprising” may also be implemented in the context of the term “consisting of” or “consisting essentially of.”


“Individual, “subject,” and “patient” are used interchangeably and can refer to a human or non-human.


Any method in the context of a therapeutic, diagnostic, or physiologic purpose or effect may also be described in “use” claim language such as “Use of” any compound, composition, or agent discussed herein for achieving or implementing a described therapeutic, diagnostic, or physiologic purpose or effect.


It is specifically contemplated that any limitation discussed with respect to one embodiment of the invention may apply to any other embodiment of the invention. Furthermore, any composition of the invention may be used in any method of the invention, and any method of the invention may be used to produce or to utilize any composition of the invention. Aspects of an embodiment set forth in the Examples are also embodiments that may be implemented in the context of embodiments discussed elsewhere in a different Example or elsewhere in the application, such as in the Summary, Detailed Description. Claims, and Brief Description of the Drawings.


Other objects, features and advantages of the present invention will become apparent from the following detailed description. It should be understood, however, that the detailed description and the specific examples, while indicating specific embodiments of the invention, are given by way of illustration only, since various changes and modifications within the spirit and scope of the invention will become apparent to those skilled in the art from this detailed description.





BRIEF DESCRIPTION OF THE DRAWINGS

The following drawings form part of the present specification and are included to further demonstrate certain aspects of the present invention. The invention may be better understood by reference to one or more of these drawings in combination with the detailed description of specific embodiments presented herein.



FIGS. 1A and 1B shows clustering of methylation sites and SCLC-subtypes in the GDSC (A) and the NCI (B) dataset. The top 1000 methylation sites for each subtype defined by AUROC analysis were selected for the analysis.



FIGS. 2A and 2B demonstrate the diagnostic performance of the models trained to predict SCLC subtypes using the top 15,000 methylation sites for each subtype. Models were trained on the NCI dataset and used to predict SCLC subtypes in the GDSC dataset in the whole dataset (solid line) and the cell lines that were unique to the GDSC dataset (dotted line). Only models created to predict the SCLC-A (A) and the SCLC-N (B) subtypes are shown. Two different models, net-elastic logistic regression (GLM) and random forest (RF), were used.



FIG. 3 demonstrates the use of combinations of two markers to predict the SCLC-A subset with models trained using the GDSC dataset. 1378 combinations were tested and results are ordered by the highest AUROC (ROC). Sensitivity (Sens) and specificity (Spec) is highlighted with the 95% CI in blue bars.



FIG. 4 demonstrates the use of combinations of two markers to predict the SCLC-N subset with models trained using the GDSC dataset. 2211 combinations were tested and results are ordered by the highest AUROC (ROC). Sensitivity (Sens) and specificity (Spec) is highlighted with the 95% CI in blue bars.



FIG. 5 shows the prediction of different SCLC subtypes using the GSE56044 dataset consisting of 124 lung cancers of different histology. AC: Adenocarcinoma. AdenoSq: Adenosquamous carcinoma. LC: Large cell carcinoma. LCNEC: Large cell neuroendocrine carcinoma. SCLC: Small cell lung cancer. SqCC: Squamous cell carcinoma.



FIG. 6 shows the prediction of subtypes using the GSE56044 dataset using large models (including 15,000 Methylation markers) and reduced panels consisting of two markers (upper heatmap) and three markers (middle heatmap) using models to specifically predict the SCLC-A subtype. AC: Adenocarcinoma. AdenoSq: Adenosquamous carcinoma. LC: Large cell carcinoma. LCNEC: Large cell neuroendocrine carcinoma. SCLC: Small cell lung cancer. SqCC: Squamous cell carcinoma.



FIG. 7 shows the prediction of subtypes using the GSE56044 dataset using large models (including 15,000 Methylation markers) and reduced panels consisting of two markers (upper heatmap) and three markers (middle heatmap) using models to specifically predict the SCLC-N subtype. AC: Adenocarcinoma. AdenoSq: Adenosquamous carcinoma. LC: Large cell carcinoma. LCNEC: Large cell neuroendocrine carcinoma. SCLC: Small cell lung cancer. SqCC: Squamous cell carcinoma.



FIG. 8 shows the prediction of subtypes using the GSE56044 dataset using large models (including 15,000 Methylation markers) and reduced panels consisting of two markers (upper heatmap) and three markers (middle heatmap) using models to specifically predict the SCLC-P subtype. AC: Adenocarcinoma. AdenoSq: Adenosquamous carcinoma. LC: Large cell carcinoma. LCNEC: Large cell neuroendocrine carcinoma. SCLC: Small cell lung cancer. SqCC: Squamous cell carcinoma.



FIG. 9 shows the prediction of subtypes using the GSE56044 dataset using large models (including 15,000 Methylation markers) and reduced panels consisting of two markers (upper heatmap) and three markers (middle heatmap) using models to specifically predict the SCLC-I subtype. AC: Adenocarcinoma. AdenoSq: Adenosquamous carcinoma. LC: Large cell carcinoma. LCNEC: Large cell neuroendocrine carcinoma. SCLC: Small cell lung cancer. SqCC: Squamous cell carcinoma.



FIGS. 10A-10C show assessment of methylation sites for their suitability in a liquid biopsy assay. Methylation levels were compared between groups and also compared to blood cells and other potential sources of cfDNA as well as real liquid biopsy samples in various cancers.



FIG. 11 shows methylation levels of markers selected to be specific for SCLC and other HGNEC. The data from the GSE60644 dataset was used consisting of 124 lung cancer samples. AC: Adenocarcinoma. AdenoSq: Adenosquamous carcinoma. LC: Large cell carcinoma. LCNEC: Large cell neuroendocrine carcinoma. SCLC: Small cell lung cancer. SqCC: Squamous cell carcinoma.



FIG. 12 shows methylation levels of markers selected to be specific for SCLC/HGNEC. The data from the pan cancer TCGA dataset was used. There are no SCLC samples in this dataset.



FIG. 13 shows correlation of methylation sites with drug response. The drug tested (IC50) is marked on the x-axis while the methylation beta value derived for each methylation site is shown on the y-axis. A trendline calculated by a linear model is added to highlight the association.



FIG. 14 shows a diagram of the analytical strategy for the selection of the respective markers following RRBS analysis described in Example 4. The markers in the final selection were further validated to be suitable in a liquid biopsy assay.



FIG. 15 shows classification of cell lines using a logistic regression model trained on the selected methylation sites based on the RRBS analysis described in Example 4. In the top row of the heatmap, the subtype classification based on the RNA signature is highlighted. The lower four rows highlight the prediction probability (Prob) for the four different SCLC subtypes (A=SCLC-A, N=SCLC-N, P=SCLC-P, I=SCLC-I). All cell lines were correctly classified.



FIG. 16 shows classification of patient-derived xenograft samples using a logistic regression model trained on the selected methylation sites from cell lines based on the RRBS analysis described in Example 4. In the top row of the heatmap, the subtype classification based on the RNA signature is highlighted. The lower four rows highlight the prediction probability (Prob) for the four different SCLC subtypes (A=SCLC-A, N=SCLC-N, P=SCLC-P, I=SCLC-I).



FIGS. 17A and 17B show a distribution of methylation sites considered suitable for a liquid biopsy across the human genome. Each chromosome is shown individually, and the sites derived from microarray analysis described in Examples 1 and 2 and from RRBS analysis described in Example 4 are highlighted according to their coordinates on the respective chromosome.



FIGS. 18A and 18B show a distribution of methylation sites that were derived from the xenograft analysis described in Example 4 and were considered useful for a liquid biopsy across the human genome. Each chromosome is shown individually and the methylation sites from RRBS analysis are highlighted according to their coordinates on the respective chromosome.



FIGS. 19A-19C show detection and classification of SCLC. FIG. 19A. Predictive models were generated to classify SCLC based on RNAseq and consensus of several combined predictive models is shown. A subtype was called when the consensus >0.5, else a sample was called equivocal. If two subtypes had consensus >50%, the sample was called both subtype (top annotation row). In addition, the expression of the three transcription factor ASCL1 (for SCLC-A), NEUROD1 (for SCLC-N) and POU2F3 (for SCLC-P) is shown with good concordance to the predictions. FIG. 19B. While the SCLC-A and SCLC-N subtypes showed a strong expression of neuroendocrine genes (NE) in RNAseq, non-neuroendocrine genes (NonNE) were enriched in the SCLC-I and SCLC-P subtypes.



FIG. 19C. The Epithelial-to-Mesenchymal (EMT) score calculated for the four subtypes highlights profound differences with a more mesenchymal phenotype in SCLC-I and a more epithelial phenotype in SCLC-P and SCLC-A. The box plot is highlighting the median as well as the 25th and 75th percentile in the box extended by 1.5× the IQR with bars.



FIGS. 20A-20G show subtype-specific DNA methylation in SCLC. FIG. 20A. DNA methylation was assessed using reduced-representation bisulfite sequencing (RRBS) and DNA methylation was averaged per sample and subtype over 100 kbp bins (represented by a dot) and the rolling average over 500 bins (=50 mbp) is highlighted in the FFPE tumor samples. DNA methylation sites were further annotated by their association with genes (including promoters, exons, introns, 1-5 kb upstream, 5UTRs, intergenic, 3UTRs, first exons, intron-exon boundaries & exon-intron boundaries) and the number of hypermethylated regions (>90% DNA methylation; FIG. 20B) per subtype and hypomethylated regions (<10% DNA methylation; FIG. 20C) is shown. Furthermore, regions which are associated with one of the four subtypes (AUROC >0.8) are highlighted in FIGS. 20D-G for SCLC-A (FIG. 20D), SCLC-N (FIG. 20E), SCLC-P (FIG. 20F) and SCLC-I (FIG. 20G).



FIGS. 21A-21C show DNA methylation-based subtyping in SCLC. FIG. 21A. A classifier using predictive models was created to predict the SCLC subtypes in FFPE samples using DNA methylation (SCLC-DMC). A subtype was called when the consensus >0.5, else a sample was called equivocal (top annotation row). Classification was compared to the RNA-based classification (top annotation row). FIG. 21B. Global DNA methylation in cfDNA of matched samples per subtype. FIG. 21C. Prediction of subtypes in cfDNA of matched samples using the SCLC-DMC.



FIGS. 22A-22D show comparison of IC50 values for the BCL2i ABT-737 (FIG. 22A) and the AURKi CYC-116 (FIG. 22B) between cell lines assigned to SCLC-A and SCLC-N using SCLC-DMC. Clinical outcome depending on classification method used. Overall survival of ES-SCLC patients stratified by classification using the RNAseq signature or SCLC-DMC for SCLC-A (FIG. 22C) and SCLC-N(FIG. 22D). The box plot is highlighting the median as well as the 25th and 75th percentile in the box extended by 1.5× the IQR with bars.



FIG. 23 shows an overview on samples used in the clinical cohort. The Size (assessed by visual inspection during extraction), whether macro dissection prior to extraction was performed as well as the finally attributed subtypes are highlighted on top. In addition the concentration of extracted RNA as well as the DV200, which is defined by the percentage of RNA fragments with a length >200 bp is shown together with the information whether the sample was used in RNAseq. Furthermore, the DNA concentration of the extracted DNA together with the information if the samples was used in RRBS DNA methylation analysis is shown. All samples were profiled by qPCR and the expression of the three transcription factors, ASCL1, NEUROD1 and POU2F3 is highlighted in the bottom, normalized to GAPDH expression.



FIGS. 24A-24C show correlation analysis of RNAseq and qPCR. Due to the low sample input and high DV200 leading to low mapping rates, the results of the RNAseq was correlated to the qPCR results for ASCL1 (FIG. 24A), NEUROD1 (FIG. 24B) and POU2F3 (FIG. 24C). The correlation coefficient using Pearson correlation as well as the p-value is highlighted for each correlation.



FIGS. 25A and 25B show expression of immune related genes in SCLC clinical specimen. FIG. 25A. Expression of different HLA genes ordered by different subtypes. Expression of HLA genes is enriched in SCLC-P and SCLC-I. FIG. 25B. Expression of different immune genes ordered by different subtypes. The expression of immune-related genes are enriched in SCLC-P and SCLC-I highlighting a more immunogenic subtype.



FIGS. 26A-26D show global DNA methylation across cell lines and xenograft models. DNA methylation was assessed using reduced-representation bisulfite sequencing (RRBS) or Methylation arrays and DNA methylation was averaged per sample and subtype over 100 kbp bins (represented by a dot) and the rolling average over 500 bins (=50 mbp) is highlighted for cell lines from the investigators provided analyzed using RRBS (FIG. 26A), cell lines derived from the NIC SCLC cell miner project (Tlemsani et al., 2020, Cell Reports 33, 108296) using the illumina EPIC array (FIG. 26B), cell lines derived from the GDSC dataset (Iorio et al., 2016, Cell, 166(3), 740-754) using the illumina 450K array (FIG. 26C), and in-house samples of patient-derived xenografts using RRBS (FIG. 26D).



FIGS. 27A-27D show a comparison of predictive DNA methylation sites between FFPE clinical samples and cell lines. DNA methylation sites that were highly associated with one of the four subtypes in cell lines and FFPE samples (AUROC >0.8) were selected and filtered for DNA methylation sites for which information was present in both datasets. DNA methylation sites which are shared among both sample types or which are unique to each are shown for SCLC-A (FIG. 27A), SCLC-N (FIG. 27B), SCLC-P (FIG. 27C) and SCLC-I (FIG. 27D).



FIGS. 28A-28C show DNA methylation sites of the three transcription factors per subtype. The four subtypes are defined by the expression of the three transcription factors ASCL1 (SCLC-A), NEUROD1 (SCLC-N) and POU2F3 (SCLC-P) as well as by absence of the three (SCLC-I). Consequently, differences in DNA methylation for different regions for each of the three transcription factors are shown per subtype for ASCL1 (FIG. 28A), NEUROD1 (FIG. 28B) and POU2F3 (FIG. 28C). The box plot is highlighting the median as well as the 25th and 75th percentile in the box extended by 1.5× the IQR with bars. Significance was calculated using two-sided student's t-test and provided for each comparison above the boxplots.



FIG. 29 shows DNA methylation sites per region per subtype. DNA methylation sites were analyzed according to their region next to a respective gene to allow further functional assessment. For each of the four subtypes, the total DNA methylation level for each of the regions is highlighted. The box plot is highlighting the median as well as the 25th and 75th percentile in the box extended by 1.5× the IQR with bars. Significance is calculated using two-sided student's t-test and provided for each comparison above the boxplots.



FIG. 30 shows classification of cell lines using the SCLC-DMC. The same model that was trained on the clinical specimens was used to predict the subtype in 59 cell lines. The heatmap highlights the consensus prediction of the models.



FIGS. 31A and 31B show global DNA methylation across cfDNA samples. DNA methylation was assessed using reduced-representation bisulfite sequencing (RRBS) and DNA methylation was averaged per sample and subtype over 100 kbp bins. FIG. 31A. To assess the differences of cfDNA to FFPE DNA, matched samples were selected and the differences for each bin is highlighted in (represented by a dot) and the rolling average over 500 bins (=50 mbp) for each sample individually. FIG. 31B. The global methylation pattern in cfDNA is highlighted for each sample individually likewise with each dot representing a bin of 100 kbp and the line the rolling average of 500 bins. In addition to comparing the results to cfDNA from healthy donors, data was retrieved from (Van Paemel et al., 2021, Epigenetics, 33074045) and is highlighted by average across all provided samples.





DETAILED DESCRIPTION

Using mRNA gene expression patterns, tumors from SCLC patients can be classified into four major subtypes of SCLC. Three of them are defined by differential expression of the transcription factors ASCL1 (SCLC-A), NEUROD1 (SCLC-N), and POU2F3 (SCLC-P), and a fourth group is characterized for having high expression of inflammatory-related genes (SCLC-I). Importantly, these subtypes have distinct therapeutic vulnerabilities and show differential response patterns to standard of care and investigation agents. Similar subgroups also exist in other HGNEC, such as Large Cell Neuroendocrine Carcinoma of the lung. Certain methods for such classification and treatment of SCLC and HGNEC are described in U.S. Patent Application Publication 2021/0062274 and Gay C M, et al., Cancer Cell. 2021 Jan. 5:S1535-6108(20)30662-0, each incorporated by reference herein in its entirety.


The present disclosure is based, at least in part, on the discovery that certain DNA methylation sites can be used to identify and classify small cell lung cancer and its subtypes (SCLC-A, SCLC-N, SCLC-P, and SCLC-I), and can also be used to inform treatment decisions for SCLC patients. Aspects of the present disclosure describe analysis of DNA methylation from tumor tissue, blood, or other sources for classification and treatment of SCLC and HGNEC. Certain aspects are directed to methods for identifying a patient as having SCLC-A, SCLC-N, SCLC-P, or SCLC-I based on analysis of methylation sites of tumor DNA from the subject including, for example, the methylation sites of Table 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 26, 27, 28, 29, and/or 30. For example, a subject may be identified as having a particular SCLC subtype based on identifying differential methylation of at least or at most 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 200, 300, 400, 500, 600, 700, 800, 900, or 1000 methylation sites (or any range or value derivable therein) of Table 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 26, 27, 28, 29, and/or 30. It is specifically contemplated that any combination of any 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 200, 300, 400, 500, 600, 700, 800, 900, or 1000 methylation sites (or any range or value derivable therein) of Table 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 26, 27, 28, 29, and/or 30 may be included in a method, composition, or kit of the present disclosure. It is specifically contemplated that any 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 200, 300, 400, 500, 600, 700, 800, 900, or 1000 methylation sites (or any range or value derivable therein), or more, methylation sites of Table 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 26, 27, 28, 29, and/or 30 may be excluded in embodiments described herein.


Additional aspects are directed to methods for identifying a subject with cancer as having SCLC based on analysis of methylation sites of tumor DNA from the subject including, for example, the methylation sites of Table 13. For example, a subject may be identifying as having SCLC, and not as having a different cancer type, based on identification of differential methylation of one or more of the methylation sites of Table 13.


Further aspects relate to methods for treatment of SCLC or HGNEC based on analysis of methylation sites of tumor DNA from the subject including, for example, the methylation sites of Table 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 26, 27, 28, 29, and/or 30. For example, a subject may be treated for SCLC with a particular treatment based on identifying differential methylation of at least or at most 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 200, 300, 400, 500, 600, 700, 800, 900, or 1000 of the methylation sites of Tables 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 26, 27, 28, 29, and/or 30. Example therapies useful in treatment of a particular SCLC subtype are described herein. It is specifically contemplated that 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 200, 300, 400, 500, 600, 700, 800, 900, or 1000 methylation sites (or any range or value derivable therein), or more, methylation sites of Tables 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 26, 27, 28, 29, and/or 30 may be excluded in embodiments described herein.


I. Treatment Methods

Aspects of the present disclosure include methods of treating a patient with small cell lung cancer (SCLC) or other high-grade neuroendocrine carcinoma (HGNEC). Certain aspects are directed to methods for treatment of a subject for SCLC, where the treatment is selected based on the SCLC subtype of the subject. As described herein, a subject may have SCLC, where the SCLC can be classified as one of four subtypes: SCLC-A, SCLC-N, SCLC-P, or SCLC-I.


In some embodiments, the subject is identified as having an SCLC subtype based on the expression or methylation status of ASCL1, NEUROD1, and POU2F3 in nucleic acid from cancer tissue from the subject. SCLC-A may be identified based on expression of ASCL1 and lack of expression of NEUROD1 or POU2F3. SCLC-N may be identified based on expression of NEUROD1 and lack of expression of either ASCL1 or POU2F3. SCLC-P may be identified based on expression of POU2F3 and lack of expression of either ASCL1 or NEUROD1. SCLC-I may be identified based on lack of expression of any of ASCL1, NEUROD1, and POU2F3.


In some embodiments, the subject is identified as having an SCLC subtype based on analysis of the methylation status of at least or at most 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127, 128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 145, 146, 147, 148, 149, 150, 151, 152, 153, 154, 155, 156, 157, 158, 159, 160, 161, 162, 163, 164, 165, 166, 167, 168, 169, 170, 171, 172, 173, 174, 175, 176, 177, 178, 179, 180, 181, 182, 183, 184, 185, 186, 187, 188, 189, 190, 191, 192, 193, 194, 195, 196, 197, 198, 199, 200, 201, 202, 203, 204, 205, 206, 207, 208, 209, 210, 211, 212, 213, 214, 215, 216, 217, 218, 219, 220, 221, 222, 223, 224, 225, 226, 227, 228, 229, 230, 231, 232, 233, 234, 235, 236, 237, 238, 239, 240, 241, 242, 243, 244, 245, 246, 247, 248, 249, 250, 251, 252, 253, 254, 255, 256, 257, 258, 259, 260, 261, 262, 263, 264, 265, 266, 267, 268, 269, 270, 271, 272, 273, 274, 275, 276, 277, 278, 279, 280, 281, 282, 283, 284, 285, 286, 287, 288, 289, 290, 291, 292, 293, 294, 295, 296, 297, 298, 299, 300, 301, 302, 303, 304, 305, 306, 307, 308, 309, 310, 311, 312, 313, 314, 315, 316, 317, 318, 319, 320, 321, 322, 323, 324, 325, 326, 327, 328, 329, 330, 331, 332, 333, 334, 335, 336, 337, 338, 339, 340, 341, 342, 343, 344, 345, 346, 347, 348, 349, 350, 351, 352, 353, 354, 355, 356, 357, 358, 359, 360, 361, 362, 363, 364, 365, 366, 367, 368, 369, 370, 371, 372, 373, 374, 375, 376, 377, 378, 379, 380, 381, 382, 383, 384, 385, 386, 387, 388, 389, 390, 391, 392, 393, 394, 395, 396, 397, 398, 399, 400, 401, 402, 403, 404, 405, 406, 407, 408, 409, 410, 411, 412, 413, 414, 415, 416, 417, 418, 419, 420, 421, 422, 423, 424, 425, 426, 427, 428, 429, 430, 431, 432, 433, 434, 435, 436, 437, 438, 439, 440, 441, 442, 443, 444, 445, 446, 447, 448, 449, 450, 451, 452, 453, 454, 455, 456, 457, 458, 459, 460, 461, 462, 463, 464, 465, 466, 467, 468, 469, 470, 471, 472, 473, 474, 475, 476, 477, 478, 479, 480, 481, 482, 483, 484, 485, 486, 487, 488, 489, 490, 491, 492, 493, 494, 495, 496, 497, 498, 499, 500, 501, 502, 503, 504, 505, 506, 507, 508, 509, 510, 511, 512, 513, 514, 515, 516, 517, 518, 519, 520, 521, 522, 523, 524, 525, 526, 527, 528, 529, 530, 531, 532, 533, 534, 535, 536, 537, 538, 539, 540, 541, 542, 543, 544, 545, 546, 547, 548, 549, 550, 551, 552, 553, 554, 555, 556, 557, 558, 559, 560, 561, 562, 563, 564, 565, 566, 567, 568, 569, 570, 571, 572, 600, 700, 800, 900, or 1000 methylation sites of Tables 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 26, 27, 28, 29, and/or 30 from tumor DNA from the subject. Analyses of each and every specific combination of the methylation sites of Tables 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 26, 27, 28, 29, and/or 30 are contemplated herein. It is specifically contemplated that any one or more of the methylation sites of Tables 1, 2. 3, 4, 5, 6, 7, 8, 9, 10, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 26, 27, 28, 29, and/or 30 may be excluded in embodiments described herein. In some embodiments, tumor DNA is obtained or derived from a tissue sample from the subject. In some embodiments, tumor DNA is obtained or derived from a blood sample from a subject. In some embodiments, tumor DNA is obtained or derived from a plasma sample from a subject. In some embodiments, the tumor DNA is circulating tumor DNA (ctDNA).


In some embodiments, SCLC-A is identified based on detection of differential methylation at at least or at most 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127, 128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 145, 146, 147, 148, 149, 150, 151, 152, 153, 154, 155, 156, 157, 158, 159, 160, 161, 162, 163, 164, 165, 166, 167, 168, 169, 170, 171, 172, 173, 174, 175, 176, 177, 178, 179, 180, 181, 182, 183, 184, 185, 186, 187, 188, 189, 190, 191, 192, 193, 194, 195, 196, 197, 198, 199, 200, 201, 202, 203, 204, 205, 206, 207, 208, 209, 210, 211, 212, 213, 214, 215, 216, 217, 218, 219, 220, 221, 222, 223, 224, 225, 226, 227, 228, 229, 230, 231, 232, 233, 234, 235, 236, 237, 238, 239, 240, 241, 242, 243, 244, 245, 246, 247, 248, 249, 250, 251, 252, 253, 254, 255, 256, 257, 258, 259, 260, 261, 262, 263, 264, 265, 266, 267, 268, 269, 270, 271, 272, 273, 274, 275, 276, 277, 278, 279, 280, 281, 282, 283, 284, 285, 286, 287, 288, 289, 290, 291, 292, 293, 294, 295, 296, 297, 298, 299, 300, 301, 302, 303, 304, 305, 306, 307, 308, 309, 310, 311, 312, 313, 314, 315, 316, 317, 318, 319, 320, 321, 322, 323, 324, 325, 326, 327, 328, 329, 330, 331, 332, 333, 334, 335, 336, 337, 338, 339, 340, 341, 342, 343, 344, 345, 346, 347, 348, 349, 350, 351, 352, 353, 354, 355, 356, 357, 358, 359, 360, 361, 362, 363, 364, 365, 366, 367, 368, 369, 370, 371, 372, 373, 374, 375, 376, 377, 378, 379, 380, 381, 382, 383, 384, 385, 386, 387, 388, 389, 390, 391, 392, 393, 394, 395, 396, 397, 398, 399, 400, 401, 402, 403, 404, 405, 406, 407, 408, 409, 410, 411, 412, 413, 414, 415, 416, 417, 418, 419, 420, 421, 422, 423, 424, 425, 426, 427, 428, 429, 430, 431, 432, 433, 434, 435, 436, 437, 438, 439, 440, 441, 442, 443, 444, 445, 446, 447, 448, 449, 450, 451, 452, 453, 454, 455, 456, 457, 458, 459, 460, 461, 462, 463, 464, 465, 466, 467, 468, 469, 470, 471, 472, 473, 474, 475, 476, 477, 478, 479, 480, 481, 482, 483, 484, 485, 486, 487, 488, 489, 490, 491, 492, 493, 494, 495, 496, 497, 498, 499, 500, 501, 502, 503, 504, 505, 506, 507, 508, 509, 510, 511, 512, 513, 514, 515, 516, 517, 518, 519, 520, 521, 522, 523, 524, 525, 526, 527, 528, 529, 530, 531, 532, 533, 534, 535, 536, 537, 538, 539, 540, 541, 542, 543, 544, 545, 546, 547, 548, 549, 550, 551, 552, 553, 554, 555, 556, 557, 558, 559, 560, 561, 562, 563, 564, 565, 566, 567, 568, 569, 570, 571, 572, 600, 700, 800, 900, or 1000 methylation sites of Table 2. Analyses of each and every specific combination of the methylation sites of Table 2 are contemplated herein. It is specifically contemplated that any one or more of the methylation sites of Table 2 may be excluded in embodiments described herein. In some embodiments, SCLC-A is identified based on detection of differential methylation at at least or at most 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30 methylation sites of Table 7. Analyses of each and every specific combination of the methylation sites of Table 7 are contemplated herein. It is specifically contemplated that any one or more of the methylation sites of Table 7 may be excluded in embodiments described herein. In some embodiments, SCLC-A is identified based on detection of differential methylation at at least or at most 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29.30 methylation sites of Table 15. Analyses of each and every specific combination of the methylation sites of Table 15 are contemplated herein. It is specifically contemplated that any one or more of the methylation sites of Table 15 may be excluded in embodiments described herein. In some embodiments, SCLC-A is identified based on detection of differential methylation at at least or at most 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127, 128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 145, 146, 147, 148, 149, 150, 151, 152, 153, 154, 155, 156, 157, 158, 159, 160, 161, 162, 163, 164, 165, 166, 167, 168, 169, 170, 171, 172, 173, 174, 175, 176, 177, 178, 179, 180, 181, 182, 183, 184, 185, 186, 187, 188, 189, 190, 191, 192, 193, 194, 195, 196, 197, 198, 199, 200, 201, 202, 203, 204, 205, 206, 207, 208, 209, 210, 211, 212, 213, 214, 215, 216, 217, 218, 219, 220, 221, 222, 223, 224, 225, 226, 227, 228, 229, 230, 231, 232, 233, 234, 235, 236, 237, 238, 239, 240, 241, 242, 243, 244, 245, 246, 247, 248, 249, 250, 251, 252, 253, 254, 255, 256, 257, 258, 259, 260, 261, 262, 263, 264, 265, 266, 267, 268, 269, 270, 271, 272, 273, 274, 275, 276, 277, 278, 279, 280, 281, 282, 283, 284, 285, 286, 287, 288, 289, 290, 291, 292, 293, 294, 295, 296, 297, 298, 299, 300, 301, 302, 303, 304, 305, 306, 307, 308, 309, 310, 311, 312, 313, 314, 315, 316, 317, 318, 319, 320, 321, 322, 323, 324, 325, 326, 327, 328, 329, 330, 331, 332, 333, 334, 335, 336, 337, 338, 339, 340, 341, 342, 343, 344, 345, 346, 347, 348, 349, 350, 351, 352, 353, 354, 355, 356, 357, 358, 359, 360, 361, 362, 363, 364, 365, 366, 367, 368, 369, 370, 371, 372, 373, 374, 375, 376, 377, 378, 379, 380, 381, 382, 383, 384, 385, 386, 387, 388, 389, 390, 391, 392, 393, 394, 395, 396, 397, 398, 399, 400, 401, 402, 403, 404, 405, 406, 407, 408, 409, 410, 411, 412, 413, 414, 415, 416, 417, 418, 419, 420, 421, 422, 423, 424, 425, 426, 427, 428, 429, 430, 431, 432, 433, 434, 435, 436, 437, 438, 439, 440, 441, 442, 443, 444, 445, 446, 447, 448, 449, 450, 451, 452, 453, 454, 455, 456, 457, 458, 459, 460, 461, 462, 463, 464, 465, 466, 467, 468, 469, 470, 471, 472, 473, 474, 475, 476, 477, 478, 479, 480, 481, 482, 483, 484, 485, 486, 487, 488, 489, 490, 491, 492, 493, 494, 495, 496, 497, 498, 499, 500, 501, 502, 503, 504, 505, 506, 507, 508, 509, 510, 511, 512, 513, 514, 515, 516, 517, 518, 519, 520, 521, 522, 523, 524, 525, 526, 527, 528, 529, 530, 531, 532, 533, 534, 535, 536, 537, 538, 539, 540, 541, 542, 543, 544, 545, 546, 547, 548, 549, 550, 551, 552, 553, 554, 555, 556, 557, 558, 559, 560, 561, 562, 563, 564, 565, 566, 567, 568, 569, 570, 571, 572, 600, 700, 800, 900, 1000, 1100, 1200, 1300, or 1340 methylation sites of Table 20. Analyses of each and every specific combination of the methylation sites of Table 20 are contemplated herein. It is specifically contemplated that any one or more of the methylation sites of Table 20 may be excluded in embodiments described herein. In some embodiments, SCLC-A is identified based on detection of differential methylation at at least or at most 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127, 128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 145, 146, 147, 148, 149, 150, 151, 152, 153, 154, 155, 156, 157, 158, 159, 160, 161, 162, 163, 164, 165, 166, 167, 168, 169, 170, 171, 172, 173, 174, 175, 176, 177, 178, 179, 180, 181, 182, 183, 184, 185, 186, 187, 188, 189, 190, 191, 192, 193, 194, 195, 196, 197, 198, 199, 200, 201, 202, 203, 204, 205, 206, 207, 208, 209, 210, 211, 212, 213, 214, 215, 216, 217, 218, 219, 220, 221, 222, 223, 224, 225, 226, 227, 228, 229, 230, 231, 232, 233, 234, 235, 236, 237, 238, 239, 240, 241, 242, 243, 244, 245, 246, 247, 248, 249, 250, 251, 252, 253, 254, 255, 256, 257, 258, 259, 260, 261, 262, 263, 264, 265, 266, 267, 268, 269, 270, 271, 272, 273, 274, 275, 276, 277, 278, 279, 280, 281, 282, 283, 284, 285, 286, 287, 288, 289, 290, 291, 292, 293, 294, 295, 296, 297, 298, 299, 300, 301, 302, 303, 304, 305, 306, 307, 308, 309, 310, 311, 312, 313, 314, 315, 316, 317, 318, 319, 320, 321, 322, 323, 324, 325, 326, 327, 328, 329, 330, 331, 332, 333, 334, 335, 336, 337, 338, 339, 340, 341, 342, 343, 344, 345, 346, 347, 348, 349, 350, 351, 352, 353, 354, 355, 356, 357, 358, 359, 360, 361, 362, 363, 364, 365, 366, 367, 368, 369, 370, 371, 372, 373, 374, 375, 376, 377, 378, 379, 380, 381, 382, 383, 384, 385, 386, 387, 388, 389, 390, 391, 392, 393, 394, 395, 396, 397, 398, 399, 400, 401, 402, 403, 404, 405, 406, 407, 408, 409, 410, 411, 412, 413, 414, 415, 416, 417, 418, 419, 420, 421, 422, 423, 424, 425, 426, 427, 428, 429, 430, 431, 432, 433, 434, 435, 436, 437, 438, 439, 440, 441, 442, 443, 444, 445, 446, 447, 448, 449, 450, 451, 452, 453, 454, 455, 456, 457, 458, 459, 460, 461, 462, 463, 464, 465, 466, 467, 468, 469, 470, 471, 472, 473, 474, 475, 476, 477, 478, 479, 480, 481, 482, 483, 484, 485, 486, 487, 488, 489, 490, 491, 492, 493, 494, 495, 496, 497, 498, 499, 500 methylation sites of Table 27. Analyses of each and every specific combination of the methylation sites of Table 27 are contemplated herein. It is specifically contemplated that any one or more of the methylation sites of Table 27 may be excluded in embodiments described herein. In some embodiments, SCLC-A is identified based on detection of differential methylation of cg00799539, cg04610718, cg10672201, cg17277939, cg11201256, cg07639982, cg01566028, cg06043710, cg01154505, cg09643186, cg03817675, cg00090674, cg02639667, cg22053861, cg14338051, cg00794178, cg16860004, cg04317756, cg01942646, cg11249931, cg08279731, cg05161074, cg00773370, cg07444408, cg08758185, cg27119612, cg22904437, cg04506569, cg04877165, and/or cg01610165. In some embodiments, SCLC-A is identified based on detection of differential methylation of chr17:74961036, chr17:74961013, chr18:59062159, chr19:13506705, chr9:134815629, chr21:41180000, chr9:93014411, chr9:114211349, chr9:134810271, chr19:3385734, chr6:51213948, chr18:27786347, chr6:168638645, chr9:134815657, chr9:134815611, chr16:84519934, chr20:20364625, chr5:172103442, chr20:22598951, chr16:85355101, chr9:134815628, chr20:20364629, chr19:511206, chr6:168149181, chr7:100122306, chr16:84519930, chr8:58989473, chr18:27786294, chr20:22557408, chr9:128177708, chr7:157633760, chr6:40349351, chr6:157229362, chr13:84927994, chr4:8101279, chr22:41667328, chr5:176843804, chr5:176529007, chr4:137426451, chr6:40349318, chr11:11578650, chr20:20364628, chr6:40349319, chr17:48190199, chr7:100122301, chr1:226589216, chr22:40022901, chr6:37078047, chr9:134765725, chr20:20364641, chr18:77020770, chr17:3695881, chr19:38253123, chr9:114255802, chr7:157017749, chr17:74823356, chr9:117355642, chr6:51213976, chr7:151045548, chr16:4537495, chr2:45274755, chr8:139674518, chr12:132134577, chr9:134885740, chr16:4537572, chr17:1961091, chr6:51213977, chr11:888785, chr9:134815626, chr13:110011941, chr19:13372294, chr16:84519955, chr20:20364626, chr20:20364640, chr17:57874806, chr6:168638634, chr7:14372215, chr22:50010360, chr14:56814573, chr13:112641259, chr7:146633722, chr7:157633743, chr21:43758530, chr6:168538915, chr5:176843791, chr2:46983311, chr2:239300749, chr7:157998148, chr6:34128215, chr13:112106712, chr16:3999700, chr9:114172063, chr9:134792142, chr11:11578688, chr7:157833048, chr1:151346323, chr21:38661697, chr1:226588954, chr20:6232329, chr9:134792130, chr9:134785070, chr9:134815627, chr9:134592825, chr16:84519980, chr7:100122290, chr11:11973687, chr19:38253193, chr14:44405368, chr16:4260161, chr2:28411073, chr1:50214861, chr16:84519943, chr22:19933408, chr11:68833022, chr7:73985377, chr9:93014375, chr9:114183920, chr16:4260632, chr9:133558991, chr6:168638701, chr7:157658598, chr19:13506729, chr19:13483181, chr16:84519942, chr11:76784947, chr11:65551424, chr7:2193699, chr5:179258981, chr14:99518884, chr18:27786301, chr11:64056580, chr6:169251928, chr9:134486435, chr12:132134595, chr16:84519935, chr21:41179996, chr14:105392911, chr7:40330569, chr13:111622152, chr2:98823202, chr17:29972557, chr9:134815918, chr1:213905614, chr7:2607131, chr4:8101234, chr12:103012503, chr14:44262090, chr6:82363058, chr9:114170339, chr6:168138608, chr12:11856447, chr19:13634667, chr9:93722421, chr9:114172123, chr17:29565848, chr11:64353390, chr9:90908530, chr16:3999757, chr11:65551425, chr9:114306707, chr19:2354863, chr9:136289024, chr6:107633714, chr7:157017791, chr6:168496984, chr3:45819148, chr18:77102188, chr12:105784446, chr17:29972550, chr11:119702010, chr5:1316124, chr7:73966925, chr3:53702765, chr11:118924054, chr19:51077543, chr17:81246338, chr12:3077928, chr12:130460997, chr7:157963798, chr12:130483815, chr7:157963771, chr14:64942593, chr18:59203056, chr19:13463517, chr20:20364646, chr7:157987469, chr2:216380208, chr20:16806905, chr17:74961041, chr3:176190636, chr20:22652824, chr6:37078083, chr14:44405319, chr18:72677631, chr9:136686592, chr2:216986073, chr2:10040203, chr21:38636406, chr9:134824994, chr12:119158214, chr7:5795946, chr22:19933350, chr9:134785048, chr13:111559772, chr16:88640994, chr17:29972549, chr6:168130574, chr6:168130602, chr9:114183394, chr9:120326115, chr3:177516507, chr7:110084403, chr22:50010361, chr18:76681573, chr7:158485004, chr21:38661630, chr15:53659351, chr19:13347369, chr19:39163809, chr17:48620272, chr18:71652249, chr6:168667391, chr10:133309889, chr1:241210311, chr19:46770637, chr20:22556743, chr2:47227055, chr7:150974698, chr20:22653042, chr14:73228468, chr19:18422970, chr21:40144935, chr16:85355024, chr19:13575256, chr9:134690692, chr6:82363052, chr7:122307220, chr7:157633801, chr1:43439683, chr16:64387, chr2:216986079, chr9:134885778, chr4:128846433, chr1:43550363, chr3:9180988, chr19:511219, chr20:62711715, chr11:47327260, chr6:51214001, chr5:10652237, chr4:6944534, chr21:38599607, chr6:168440545, chr1:18794157, chr8:52150618, chr9:133662377, chr16:4537619, chr19:39307494, chr19:55254005, chr12:130535047, chr5:82804, chr6:34128233, chr12:11856451, chr19:13506452, chr17:77452817, chr6:109290309, chr21:38661664, chr10:133309857, chr21:34667592, chr7:100477920, chr20:38294975, chr21:41648785, chr21:43758525, chr9:134822835, chr16:3728390, chr16:29604945, chr1:41727346, chr21:45032479, chr1:39954061, chr17:29972554, chr6:151809197, chr12:111287675, chr19:13463510, chr8:52150574, chr19:13014442, chr4:8164496, chr7:8417325, chr7:157673872, chr2:107461969, chr9:36781051, chr4:138912435, chr7:157594362, chr2:237733847, chr20:22652808, chr14:64942648, chr16:4260588, chr7:157603987, chr7:157540317, chr13:111515678, chr17:67488327, chr7:73990185, chr10:43849791, chr17:1961149, chr6:82585382, chr1:224184849, chr2:182053988, chr21:41508507, chr15:85942771, chr10:78139388, chr9:126420967, chr15:67806290, chr7:157963797, chr9:113593968, chr7:157875450, chr7:157875495, chr14:64942637, chr19:55254025, chr1:205447752, chr16:84519956, chr9:134797123, chr18:63207225, chr9:134772536, chr8:38495018, chr13:112107447, chr5:100864671, chr14:91418510, chr9:134768753, chr19:13245332, chr11:47327256, chr8:42275934, chr12:103165897, chr18:38714972, chr7:157824560, chr14:75978696, chr15:40873466, chr4:104663323, chr5:1316150, chr4:189096959, chr9:134750430, chr13:98405890, chr9:134825870, chr16:52621839, chr17:62653135, chr9:134881575, chr7:157633794, chr9:114170237, chr18:77020828, chr2:216840164, chr2:181684626, chr9:134819274, chr21:34743983, chr17:57874702, chr22:28923959, chr21:44698714, chr11:65551324, chr9:113593972, chr7:2193759, chr6:168440498, chr8:141264221, chr16:4260115, chr16:4537502, chr20:20365491, chr1:7491237, chr20:20364647, chr11:31893506, chr19:41704632, chr20:17068564, chr5:6543207, chr19:41323849, chr2:85733778, chr7:157685012, chr11:75240135, chr6:168315218, chr14:64633473, chr11:20056293, chr14:44379797, chr16:4537618, chr7:157864088, chr10:133309864, chr14:88256419, chr16:19425106, chr6:168355227, chr9:134765734, chr6:168453036, chr21:41490949, chr7:73989381, chr12:3077894, chr1:53462420, chr9:113593928, chr10:133309740, chr7:101666174, chr11:14974476, chr5:100944956, chr20:22557482, chr18:74782855, chr19:3656386, chr7:26397761, chr19:13463491, chr22:38087144, chr9:130535984, chr9:134892203, chr13:107429178, chr19:38253194, chr17:82078952, chr1:1174126, chr1:232307467, chr6:14499964, chr16:4260566, chr16:85286422, chr17:74006568, chr7:101707772, chr6:168496991, chr18:27786339, chr13:113793557, chr19:47209566, chr2:113325550, chr5:176529022, chr8:52150549, chr9:113594013, chr9:134490841, chr7:1620862, chr9:134179005, chr15:63053313, chr12:124617614, chr21:45032480, chr13:113723025, chr7:150945169, chr12:6961918, chr19:39307859, chr16:89948104, chr19:8153491, chr20:20365487, chr20:38294974, chr3:73790643, chr6:153237290, chr6:168130594, chr7:2524564, chr9:134785301, chr9:136367817, chr19:38253176, chr19:406561, chr1:52633297, chr9:93819344, chr11:76784948, chr14:36524358, chr13:112106739, chr6:157228665, chr7:157953525, chr10:101780858, chr12:110942244, chr6:43578006, chr2:51027486, chr7:157685871, chr21:45032448, chr21:45032452, chr7:157017829, chr11:65551413, chr7:157544388, chr6:50845964, chr5:138650055, chr1:229147368, chr9:134782536, chr9:134316337, chr12:124259764, chr11:11578685, chr20:17068489, chr20:20365493, chr22:28923940, chr22:28923966, chr1:153536136, chr9:93861253, chr11:64540473, chr2:229672283, chr7:157633759, chr9:134534796, chr9:114170276, chr19:5950505, chr1:32885121, chr12:6962651, chr18:27786338, chr18:63207261, chr19:41704681, chr8:141289585, chr11:124895535, chr17:57874844, chr11:75335191, chr18:71337086, chr2:46983412, chr1:212589163, chr20:48751499, chr4:78056611, chr3:176814702, chr17:81246299, chr2:3940818, chr12:98238503, chr9:114170300, chr11:924647, chr19:55254024, chr2:208703401, and/or chr20:22598941, including any combination thereof.


In some embodiments, SCLC-N is identified based on detection of differential methylation at at least or at most 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127, 128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 145, 146, 147, 148, 149, 150, 151, 152, 153, 154, 155, 156, 157, 158, 159, 160, 161, 162, 163, 164, 165, 166, 167, 168, 169, 170, 171, 172, 173, 174, 175, 176, 177, 178, 179, 180, 181, 182, 183, 184, 185, 186, 187, 188, 189, 190, 191, 192, 193, 194, 195, 196, 197, 198, 199, 200, 201, 202, 203, 204, 205, 206, 207, 208, 209, 210, 211, 212, 213, 214, 215, 216, 217, 218, 219, 220, 221, 222, 223, 224, 225, 226, 227, 228, 229, 230, 231, 232, 233, 234, 235, 236, 237, 238, 239, 240, 241, 242, 243, 244, 245, 246, 247, 248, 249, 250, 251, 252, 253, 254, 255, 256, 257, 258, 259, 260, 261, 262, 263, 264, 265, 266, 267, 268, 269, 270, 271, 272, 273, 274, 275, 276, 277, 278, 279, 280, 281, 282, 283, 284, 285, 286, 287, 288, 289, 290, 291, 292, 293, 294, 295, 296, 297, 298, 299, 300, 301, 302, 303, 304, 305, 306, 307, 308, 309, 310, 311, 312, 313, 314, 315, 316, 317, 318, 319, 320, 321, 322, 323, 324, 325, 326, 327, 328, 329, 330, 331, 332, 333, 334, 335, 336, 337, 338, 339, 340, 341, 342, 343, 344, 345, 346, 347, 348, 349, 350, 351, 352, 353, 354, 355, 356, 357, 358, 359, 360, 361, 362, 363, 364, 365, 366, 367, 368, 369, 370, 371, 372, 373, 374, 375, 376, 377, 378, 379, 380, 381, 382, 383, 384, 385, 386, 387, 388, 389, 390, 391, 392, 393, 394, 395, 396, 397, 398, 399, 400, 401, 402, 403, 404, 405, 406, 407, 408, 409, 410, 411, 412, 413, 414, 415, 416, 417, 418, 419, 420, 421, 422, 423, 424, 425, 426, 427, 428, 429, 430, 431, 432, 433, 434, 435, 436, 437, 438, 439, 440, 441, 442, 443, 444, 445, 446, 447, 448, 449, 450, 451, 452, 453, 454, 455, 456, 457, 458, 459, 460, 461, 462, 463, 464, 465, 466, 467, 468, 469, 470, 471, 472, 473, 474, 475, 476, 477, 478, 479, 480, 481, 482, 483, 484, 485, 486, 487, 488, 489, 490, 491, 492, 493, 494, 495, 496, 497, 498, 499, 500, 501, 502, 503, 504, 505, 506, 507, 508, 509, 510, 511, 512, 513, 514, 515, 516, 517, 518, 519, 520, 521, 522, 523, 524, 525, 526, 527, 528, 529, 530, 531, 532, 533, 534, 535, 536, 537, 538, 539, 540, 541, 542, 543, 544, 545, 546, 547, 548, 549, 550, 551, 552, 553, 554, 555, 556, 557, 558, 559, 560, 561, 562, 563, 564, 565, 566, 567, 568, 569, 570, 571, 572, 600, 700, 800, 900, or 1000 methylation sites of Table 3. Analyses of each and every specific combination of the methylation sites of Table 3 are contemplated herein. It is specifically contemplated that any one or more of the methylation sites of Table 3 may be excluded in embodiments described herein. In some embodiments, SCLC-N is identified based on detection of differential methylation at at least or at most 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, or 46 methylation sites of Table 8. Analyses of each and every specific combination of the methylation sites of Table 8 are contemplated herein. It is specifically contemplated that any one or more of the methylation sites of Table 8 may be excluded in embodiments described herein. In some embodiments, SCLC-N is identified based on detection of differential methylation at at least or at most 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30 methylation sites of Table 16. Analyses of each and every specific combination of the methylation sites of Table 16 are contemplated herein. It is specifically contemplated that any one or more of the methylation sites of Table 16 may be excluded in embodiments described herein. In some embodiments, SCLC-N is identified based on detection of differential methylation at at least or at most 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127, 128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 145, 146, 147, 148, 149, 150, 151, 152, 153, 154, 155, 156, 157, 158, 159, 160, 161, 162, 163, 164, 165, 166, 167, 168, 169, 170, 171, 172, 173, 174, 175, 176, 177, 178, 179, 180, 181, 182, 183, 184, 185, 186, 187, 188, 189, 190, 191, 192, 193, 194, 195, 196, 197, 198, 199, 200, 201, 202, 203, 204, 205, 206, 207, 208, 209, 210, 211, 212, 213, 214, 215, 216, 217, 218, 219, 220, 221, 222, 223, 224, 225, 226, 227, 228, 229, 230, 231, 232, 233, 234, 235, 236, 237, 238, 239, 240, 241, 242, 243, 244, 245, 246, 247, 248, 249, 250, 251, 252, 253, 254, 255, 256, 257, 258, 259, 260, 261, 262, 263, 264, 265, 266, 267, 268, 269, 270, 271, 272, 273, 274, 275, 276, 277, 278, 279, 280, 281, 282, 283, 284, 285, 286, 287, 288, 289, 290, 291, 292, 293, 294, 295, 296, 297, 298, 299, 300, 301, 302, 303, 304, 305, 306, 307, 308, 309, 310, 311, 312, 313, 314, 315, 316, 317, 318, 319, 320, 321, 322, 323, 324, 325, 326, 327, 328, 329, 330, 331, 332, 333, 334, 335, 336, 337, 338, 339, 340, 341, 342, 343, 344, 345, 346, 347, 348, 349, 350, 351, 352, 353, 354, 355, 356, 357, 358, 359, 360, 361, 362, 363, 364, 365, 366, 367, 368, 369, 370, 371, 372, 373, 374, 375, 376, 377, 378, 379, 380, 381, 382, 383, 384, 385, 386, 387, 388, 389, 390, 391, 392, 393, 394, 395, 396, 397, 398, 399, 400, 401, 402, 403, 404, 405, 406, 407, 408, 409, 410, 411, 412, 413, 414, 415, 416, 417, 418, 419, 420, 421, 422, 423, 424, 425, 426, 427, 428, 429, 430, 431, 432, 433, 434, 435, 436, 437, 438, 439, 440, 441, 442, 443, 444, 445, 446, 447, 448, 449, 450, 451, 452, 453, 454, 455, 456, 457, 458, 459, 460, 461, 462, 463, 464, 465, 466, 467, 468, 469, 470, 471, 472, 473, 474, 475, 476, 477, 478, 479, 480, 481, 482, 483, 484, 485, 486, 487, 488, 489, 490, 491, 492, 493, 494, 495, 496, 497, 498, 499, 500, 501, 502, 503, 504, 505, 506, 507, 508, 509, 510, 511, 512, 513, 514, 515, 516, 517, 518, 519, 520, 521, 522, 523, 524, 525, 526, 527, 528, 529, 530, 531, 532, 533, 534, 535, 536, 537, 538, 539, 540, 541, 542, 543, 544, 545, 546, 547, 548, 549, 550, 551, 552, 553, 554, 555, 556, 557, 558, 559, 560, 561, 562, 563, 564, 565, 566, 567, 568, 569, 570, 571, 572, 600, 650, or 695 methylation sites of Table 21. It is specifically contemplated that any one or more of the methylation sites of Table 21 may be excluded in embodiments described herein. In some embodiments, SCLC-N is identified based on detection of differential methylation at at least or at most 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127, 128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 145, 146, 147, 148, 149, 150, 151, 152, 153, 154, 155, 156, 157, 158, 159, 160, 161, 162, 163, 164, 165, 166, 167, 168, 169, 170, 171, 172, 173, 174, 175, 176, 177, 178, 179, 180, 181, 182, 183, 184, 185, 186, 187, 188, 189, 190, 191, 192, 193, 194, 195, 196, 197, 198, 199, 200, 201, 202, 203, 204, 205, 206, 207, 208, 209, 210, 211, 212, 213, 214, 215, 216, 217, 218, 219, 220, 221, 222, 223, 224, 225, 226, 227, 228, 229, 230, 231, 232, 233, 234, 235, 236, 237, 238, 239, 240, 241, 242, 243, 244, 245, 246, 247, 248, 249, 250, 251, 252, 253, 254, 255, 256, 257, 258, 259, 260, 261, 262, 263, 264, 265, 266, 267, 268, 269, 270, 271, 272, 273, 274, 275, 276, 277, 278, 279, 280, 281, 282, 283, 284, 285, 286, 287, 288, 289, 290, 291, 292, 293, 294, 295, 296, 297, 298, 299, 300, 301, 302, 303, 304, 305, 306, 307, 308, 309, 310, 311, 312, 313, 314, 315, 316, 317, 318, 319, 320, 321, 322, 323, 324, 325, 326, 327, 328, 329, 330, 331, 332, 333, 334, 335, 336, 337, 338, 339, 340, 341, 342, 343, 344, 345, 346, 347, 348, 349, 350, 351, 352, 353, 354, 355, 356, 357, 358, 359, 360, 361, 362, 363, 364, 365, 366, 367, 368, 369, 370, 371, 372, 373, 374, 375, 376, 377, 378, 379, 380, 381, 382, 383, 384, 385, 386, 387, 388, 389, 390, 391, 392, 393, 394, 395, 396, 397, 398, 399, 400, 401, 402, 403, 404, 405, 406, 407, 408, 409, 410, 411, 412, 413, 414, 415, 416, 417, 418, 419, 420, 421, 422, 423, 424, 425, 426, 427, 428, 429, 430, 431, 432, 433, 434, 435, 436, 437, 438, 439, 440, 441, 442, 443, 444, 445, 446, 447, 448, 449, 450, 451, 452, 453, 454, 455, 456, 457, 458, 459, 460, 461, 462, 463, 464, 465, 466, 467, 468, 469, 470, 471, 472, 473, 474, 475, 476, 477, 478, 479, 480, 481, 482, 483, 484, 485, 486, 487, 488, 489, 490, 491, 492, 493, 494, 495, 496, 497, 498, 499, 500 methylation sites of Table 28. It is specifically contemplated that any one or more of the methylation sites of Table 28 may be excluded in embodiments described herein. In some embodiments, SCLC-N is identified based on detection of differential methylation of cg20505457, cg04220881, cg14755690, cg19798702, cg03920522, cg12187160, cg02531277, cg18780243, cg19028997, cg02314596, cg16498113, cg19513004, cg17401435, cg25043538, cg00648184, cg10414350, cg09309024, cg06440275, cg01431993, cg11528849, cg16640855, cg00369376, cg02836529, cg20806345, cg22976218, cg13538006, cg11887270, cg23731742, cg02622825, cg00284708, cg05234415, cg24657047, cg23994112, cg08399017, cg14647703, cg13969327, cg05214130, cg08573199, cg09621610, cg13417891, cg02902261, cg00678971, cg02243624, cg13808641, cg15076368, and/or cg11964216. In some embodiments, SCLC-N is identified based on detection of differential methylation of chr1:54356529, chr1:109296245, chr1:109296247, chr1:220653171, chr1:220653195, chr11:35853956, chr11:64154503, chr11:64154571, chr11:64154574, chr12:108792675, chr17:72440313, chr17:72440361, chr2:223901322, chr20:19919227, chr3:52468694, chr5:160245925, chr6:44261803, chr8:42275934, chr9:131721310, chr9:131721341, chr9:131721355, chr9:131721389, chr2:216909627, chr20:19919173, chr9:131721356, chr22:50276667, chr17:72440360, chr6:37537738, chr1:220653165, chr1:220653180, chr8:140270696, chr12:108792684, chr19:3656274, chr1:54356527, chr19:47650943, chr7:149261799, chr2:216380208, chr17:72440372, chr9:131721340, chr9:131721342, chr2:216380274, chr11:67493309, chr2:65583301, chr5:160245988, chr3:52468622, chr17:74823299, chr1:160362850, chr12:31009628, chr14:64633473, chr18:59049918, chr20:63878908, chr5:16538225, chr6:19719869, chr6:34128215, chr6:34128233, chr1:109296235, chr3:52522225, chr8:134941130, chr7:149261769, chr19:3656352, chr2:85733778, chr4:850796, chr3:126013960, chr19:3655899, chr22:44049853, chr9:120242580, chr1:41657833, chr1:220653181, chr11:8239208, chr2:65583300, chr5:16538207, chr6:34128222, chr9:131721343, chr7:149261778, chr14:105178678, chr12:31009602, chr1:28869236, chr1:220653223, chr7:44254153, chr6:43475701, chr15:68347588, chr20:49345755, chr5:160245950, chr19:3656298, chr19:3655920, chr20:49345760, chr6:34128216, chr3:52468649, chr1:944700, chr1:54356503, chr1:54356526, chr1:54356528, chr2:216909691, chr5:160245949, chr21:41490949, chr17:50076230, chr2:25702014, chr19:3655770, chr9:120242557, chr16:85439239, chr1:53320062, chr5:16538206, chr6:19719865, chr11:855989, chr19:3655921, chr6:107633786, chr19:14182660, chr19:48350598, chr3:52468650, chr16:10622418, chr3:52468678, chr11:20055879, chr2:216909621, chr6:34128193, chr16:85287295, chr1:53320061, chr7:100890535, chr12:48675723, chr2:25701951, chr20:63835624, chr4:76612797, chr6:43475769, chr3:16132696, chr11:66866493, chr12:31009572, chr1:226588954, chr16:66960251, chr19:3656369, chr17:4809230, chr7:157018053, chr20:11271495, chr17:82001560, chr17:82001559, chr2:85770228, chr20:49345801, chr21:41458778, chr6:34128249, chr11:44963230, chr1:944730, chr12:108792716, chr22:44049787, chr3:52522201, chr4:6308154, chr2:85733793, chr19:12953781, chr1:43550353, chr21:41490965, chr12:108792685, chr3:16132702, chr1:15723882, chr1:54356555, chr12:130484433, chr17:4809161, chr6:19719861, chr6:26385134, chr6:168130602, chr19:13913675, chr16:85287080, chr11:888785, chr19:3655898, chr1:1921168, chr2:200087052, chr19:2354832, chr11:129699789, chr1:28869229, chr19:18422970, chr1:944737, chr22:44049781, chr20:25239829, chr9:120242569, chr6:148509695, chr1:153536157, chr9:120242617, chr12:31009603, chr18:62333487, chr8:140270737, chr19:3655888, chr17:82001529, chr7:102424329, chr2:200087071, chr16:85287095, chr11:855972, chr11:855981, chr9:120242622, chr19:3656250, chr20:19836028, chr1:944699, chr17:2418940, chr3:185397845, chr7:44151120, chr11:35853892, chr12:123253744, chr20:49345788, chr6:34128234, chr7:750747, chr2:205764439, chr18:59050139, chr5:172103442, chr9:120242544, chr1:28869207, chr16:11997774, chr8:134499858, chr17:29158240, chr1:54356559, chr6:34545466, chr8:134941060, chr10:101780858, chr19:12953855, chr3:53702770, chr12:56997304, chr6:34128223, chr18:77053845, chr20:22557408, chr6:110414306, chr9:136013178, chr1:230759612, chr6:44261814, chr6:42963345, chr9:95738191, chr16:85355101, chr19:2354863, chr1:53320016, chr16:70318894, chr16:85696894, chr17:82001584, chr2:200087032, chr7:128075308, chr1:32885121, chr21:41665312, chr7:128881062, chr6:169160984, chr3:196992182, chr6:40349319, chr7:44151126, chr1:54356214, chr7:5276684, chr19:38253104, chr1:204921255, chr1:224184849, chr11:48025532, chr5:16538197, chr1:153536113, chr1:153536123, chr9:124820965, chr21:41639350, chr9:113901422, chr1:11965505, chr6:168638645, chr17:29582881, chr3:71074388, chr9:134486435, chr19:48350605, chr19:3656178, chr11:118901571, chr1:43550383, chr12:123253763, chr16:30030208, chr21:41648785, chr9:91810447, chr10:79313956, chr6:169190341, chr16:85436880, chr1:1921165, chr1:205447760, chr1:153536136, chr1:153536146, chr11:19730746, chr3:141093639, chr2:159228539, chr21:17508899, chr11:66866541, chr17:66830069, chr20:49345770, chr20:63835571, chr9:127200650, chr19:4055918, chr9:131810494, chr19:38253123, chr1:60903781, chr22:20014786, chr1:25771857, chr17:67652635, chr9:93166951, chr13:73218843, chr7:136045406, chr14:73228468, chr17:50831246, chr7:30171980, chr17:67652633, chr1:28869065, chr13:113818528, chr2:200087031, chr2:200087051, chr6:168517547, chr6:35534674, chr6:35534714, chr6:148509713, chr19:3656386, chr11:19832444, chr13:112775959, chr22:19632813, chr5:760546, chr19:3950318, chr1:60903756, chr7:8070969, chr16:70730157, chr20:49345761, chr3:45819148, chr6:19719834, chr6:34128254, chr6:34128257, chr6:168130634, chr1:15723893, chr16:85287162, chr7:1815269, chr9:93166950, chr16:85287116, chr17:67652568, chr12:123253794, chr16:85287098, chr18:77077978, chr19:46714207, chr3:53702765, chr7:3998211, chr9:92729620, chr16:85436709, chr11:66866538, chr22:44248796, chr6:34545471, chr7:102424320, chr17:602149, chr20:22557482, chr6:3444679, chr17:57707866, chr16:11654442, chr19:3655812, chr13:109334658, chr1:43550373, chr2:73080399, chr9:131810462, chr1:227920141, chr1:153536121, chr20:50035301, chr20:38700627, chr21:41553133, chr21:41648778, chr6:168130595, chr6:168539582, chr7:5276649, chr21:40144935, chr19:3656261, chr3:139718818, chr1:10625828, chr3:185397835, chr7:110084403, chr5:176843791, chr6:40349351, chr9:113901566, chr21:41179996, chr4:528986, chr12:48675786, chr19:13634667, chr6:168130574, chr19:3656190, chr1:202168439, chr12:124428932, chr6:34545461, chr7:3998240, chr3:127304410, chr16:89847327, chr1:226638169, chr1:181128695, chr1:54356181, chr12:123253764, chr11:64056580, chr3:47236186, chr16:85436855, chr11:888597, chr19:4010290, chr1:53320091, chr1:205257276, chr19:4010298, chr21:41648770, chr7:122306890, chr20:11271554, chr4:7911302, chr1:28869195, chr16:2455154, chr5:176843804, chr7:5276677, chr1:220653196, chr11:888641, chr19:38253076, chr4:1858204, chr8:38495138, chr3:141093636, chr1:31627824, chr12:48675768, chr2:190034714, chr6:168638690, chr19:3656351, chr12:131864061, chr9:89591607, chr17:74823356, chr16:85287017, chr16:88887476, chr2:96174325, chr6:3444622, chr1:5917479, chr1:1240684, chr12:130483799, chr13:110123705, chr6:168496991, chr8:53733503, chr7:105689129, chr2:113974997, chr12:591924, chr15:65333873, chr3:194305584, chr19:4059381, chr18:59049874, chr1:224184822, chr11:76175216, chr6:168130594, chr19:3655954, chr19:34999970, chr6:26614205, chr10:78139388, chr11:122984321, chr19:3656172, chr1:43550344, chr12:129694731, chr19:3655828, chr7:151045548, chr12:130483815, chr5:78519838, chr11:888359, chr1:205032318, chr9:120242579, chr1:16486605, chr1:20348597, chr2:43203382, chr6:168130603, chr17:3695871, chr11:19714522, chr16:85439179, chr7:122306891, chr9:130233164, chr2:47020392, chr19:3655938, chr8:58989422, chr17:80001489, chr2:5530198, chr19:3656393, chr7:1815299, chr21:43860194, chr6:168355227, chr1:20348596, chr7:5478011, chr2:200087040, chr19:48371166, chr16:22288921, chr19:12953833, chr11:888360, chr5:16538196, chr1:9251757, chr11:924646, chr12:131864094, chr2:25701937, chr6:168538915, chr9:127636823, chr1:22809032, chr17:29065994, chr6:168517537, chr4:6308178, chr1:61198659, chr20:11271453, chr7:44151141, chr19:18745096, chr7:30172111, chr6:34433316, chr12:119869919, chr13:110123752, chr17:29582888, chr18:36468445, chr19:4010297, chr19:39307494, chr20:63835620, chr21:41375919, chr5:6859175, chr6:37537680, chr7:100122236, chr9:93959419, chr9:91810580, chr17:73726103, chr1:226589216, chr9:23452269, chr6:42963307, and/or chr8:140321186, chr16:85287074, including any combination thereof.


In some embodiments, SCLC-P is identified based on detection of differential methylation at at least or at most 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127, 128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 145, 146, 147, 148, 149, 150, 151, 152, 153, 154, 155, 156, 157, 158, 159, 160, 161, 162, 163, 164, 165, 166, 167, 168, 169, 170, 171, 172, 173, 174, 175, 176, 177, 178, 179, 180, 181, 182, 183, 184, 185, 186, 187, 188, 189, 190, 191, 192, 193, 194, 195, 196, 197, 198, 199, 200, 201, 202, 203, 204, 205, 206, 207, 208, 209, 210, 211, 212, 213, 214, 215, 216, 217, 218, 219, 220, 221, 222, 223, 224, 225, 226, 227, 228, 229, 230, 231, 232, 233, 234, 235, 236, 237, 238, 239, 240, 241, 242, 243, 244, 245, 246, 247, 248, 249, 250, 251, 252, 253, 254, 255, 256, 257, 258, 259, 260, 261, 262, 263, 264, 265, 266, 267, 268, 269, 270, 271, 272, 273, 274, 275, 276, 277, 278, 279, 280, 281, 282, 283, 284, 285, 286, 287, 288, 289, 290, 291, 292, 293, 294, 295, 296, 297, 298, 299, 300, 301, 302, 303, 304, 305, 306, 307, 308, 309, 310, 311, 312, 313, 314, 315, 316, 317, 318, 319, 320, 321, 322, 323, 324, 325, 326, 327, 328, 329, 330, 331, 332, 333, 334, 335, 336, 337, 338, 339, 340, 341, 342, 343, 344, 345, 346, 347, 348, 349, 350, 351, 352, 353, 354, 355, 356, 357, 358, 359, 360, 361, 362, 363, 364, 365, 366, 367, 368, 369, 370, 371, 372, 373, 374, 375, 376, 377, 378, 379, 380, 381, 382, 383, 384, 385, 386, 387, 388, 389, 390, 391, 392, 393, 394, 395, 396, 397, 398, 399, 400, 401, 402, 403, 404, 405, 406, 407, 408, 409, 410, 411, 412, 413, 414, 415, 416, 417, 418, 419, 420, 421, 422, 423, 424, 425, 426, 427, 428, 429, 430, 431, 432, 433, 434, 435, 436, 437, 438, 439, 440, 441, 442, 443, 444, 445, 446, 447, 448, 449, 450, 451, 452, 453, 454, 455, 456, 457, 458, 459, 460, 461, 462, 463, 464, 465, 466, 467, 468, 469, 470, 471, 472, 473, 474, 475, 476, 477, 478, 479, 480, 481, 482, 483, 484, 485, 486, 487, 488, 489, 490, 491, 492, 493, 494, 495, 496, 497, 498, 499, 500, 501, 502, 503, 504, 505, 506, 507, 508, 509, 510, 511, 512, 513, 514, 515, 516, 517, 518, 519, 520, 521, 522, 523, 524, 525, 526, 527, 528, 529, 530, 531, 532, 533, 534, 535, 536, 537, 538, 539, 540, 541, 542, 543, 544, 545, 546, 547, 548, 549, 550, 551, 552, 553, 554, 555, 556, 557, 558, 559, 560, 561, 562, 563, 564, 565, 566, 567, 568, 569, 570, 571, 572, 600, 700, 800, 900, or 1000 methylation sites of Table 4. Analyses of each and every specific combination of the methylation sites of Table 4 are contemplated herein. It is specifically contemplated that any one or more of the methylation sites of Table 4 may be excluded in embodiments described herein. In some embodiments, SCLC-P is identified based on detection of differential methylation at at least or at most 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, or 93 methylation sites of Table 9. Analyses of each and every specific combination of the methylation sites of Table 9 are contemplated herein. It is specifically contemplated that any one or more of the methylation sites of Table 9 may be excluded in embodiments described herein. In some embodiments, SCLC-P is identified based on detection of differential methylation at at least or at most 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30 methylation sites of Table 17. Analyses of each and every specific combination of the methylation sites of Table 17 are contemplated herein. It is specifically contemplated that any one or more of the methylation sites of Table 17 may be excluded in embodiments described herein. In some embodiments, SCLC-P is identified based on detection of differential methylation at at least or at most 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127, 128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 145, 146, 147, 148, 149, 150, 151, 152, 153, 154, 155, 156, 157, 158, 159, 160, 161, 162, 163, 164, 165, 166, 167, 168, 169, 170, 171, 172, 173, 174, 175, 176, 177, 178, 179, 180, 181, 182, 183, 184, 185, 186, 187, 188, 189, 190, 191, 192, 193, 194, 195, 196, 197, 198, 199, 200, 201, 202, 203, 204, 205, 206, 207, 208, 209, 210, 211, 212, 213, 214, 215, 216, 217, 218, 219, 220, 221, 222, 223, 224, 225, 226, 227, 228, 229, 230, 231, 232, 233, 234, 235, 236, 237, 238, 239, 240, 241, 242, 243, 244, 245, 246, 247, 248, 249, 250, 251, 252, 253, 254, 255, 256, 257, 258, 259, 260, 261, 262, 263, 264, 265, 266, 267, 268, 269, 270, 271, 272, 273, 274, 275, 276, 277, 278, 279, 280, 281, 282, 283, 284, 285, 286, 287, 288, 289, 290, 291, 292, 293, 294, 295, 296, 297, 298, 299, 300, 301, 302, 303, 304, 305, 306, 307, 308, 309, 310, 311, 312, 313, 314, 315, 316, 317, 318, 319, 320, 321, 322, 323, 324, 325, 326, 327, 328, 329, 330, 331, 332, 333, 334, 335, 336, 337, 338, 339, 340, 341, 342, 343, 344, 345, 346, 347, 348, 349, 350, 351, 352, 353, 354, 355, 356, 357, 358, 359, 360, 361, 362, 363, 364, 365, 366, 367, 368, 369, 370, 371, 372, 373, 374, 375, 376, 377, 378, 379, 380, 381, 382, 383, 384, 385, 386, 387, 388, 389, 390, 391, 392, 393, 394, 395, 396, 397, 398, 399, 400, 401, 402, 403, 404, 405, 406, 407, 408, 409, 410, 411, 412, 413, 414, 415, 416, 417, 418, 419, 420, 421, 422, 423, 424, 425, 426, 427, 428, 429, 430, 431, 432, 433, 434, 435, 436, 437, 438, 439, 440, 441, 442, 443, 444, 445, 446, 447, 448, 449, 450, 451, 452, 453, 454, 455, 456, 457, 458, 459, 460, 461, 462, 463, 464, 465, 466, 467, 468, 469, 470, 471, 472, 473, 474, 475, 476, 477, 478, 479, 480, 481, 482, 483, 484, 485, 486, 487, 488, 489, 490, 491, 492, 493, 494, 495, 496, 497, 498, 499, 500, 501, 502, 503, 504, 505, 506, 507, 508, 509, 510, 511, 512, 513, 514, 515, 516, 517, 518, 519, 520, 521, 522, 523, 524, 525, 526, 527, 528, 529, 530, 531, 532, 533, 534, 535, 536, 537, 538, 539, 540, 541, 542, 543, 544, 545, 546, 547, 548, 549, 550, 551, 552, 553, 554, 555, 556, 557, 558, 559, 560, 561, 562, 563, 564, 565, 566, 567, 568, 569, 570, 571, 572, 600, 700, 800, 900, or 989 methylation sites of Table 22. Analyses of each and every specific combination of the methylation sites of Table 22 are contemplated herein. It is specifically contemplated that any one or more of the methylation sites of Table 22 may be excluded in embodiments described herein. In some embodiments, SCLC-P is identified based on detection of differential methylation at at least or at most 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127, 128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 145, 146, 147, 148, 149, 150, 151, 152, 153, 154, 155, 156, 157, 158, 159, 160, 161, 162, 163, 164, 165, 166, 167, 168, 169, 170, 171, 172, 173, 174, 175, 176, 177, 178, 179, 180, 181, 182, 183, 184, 185, 186, 187, 188, 189, 190, 191, 192, 193, 194, 195, 196, 197, 198, 199, 200, 201, 202, 203, 204, 205, 206, 207, 208, 209, 210, 211, 212, 213, 214, 215, 216, 217, 218, 219, 220, 221, 222, 223, 224, 225, 226, 227, 228, 229, 230, 231, 232, 233, 234, 235, 236, 237, 238, 239, 240, 241, 242, 243, 244, 245, 246, 247, 248, 249, 250, 251, 252, 253, 254, 255, 256, 257, 258, 259, 260, 261, 262, 263, 264, 265, 266, 267, 268, 269, 270, 271, 272, 273, 274, 275, 276, 277, 278, 279, 280, 281, 282, 283, 284, 285, 286, 287, 288, 289, 290, 291, 292, 293, 294, 295, 296, 297, 298, 299, 300, 301, 302, 303, 304, 305, 306, 307, 308, 309, 310, 311, 312, 313, 314, 315, 316, 317, 318, 319, 320, 321, 322, 323, 324, 325, 326, 327, 328, 329, 330, 331, 332, 333, 334, 335, 336, 337, 338, 339, 340, 341, 342, 343, 344, 345, 346, 347, 348, 349, 350, 351, 352, 353, 354, 355, 356, 357, 358, 359, 360, 361, 362, 363, 364, 365, 366, 367, 368, 369, 370, 371, 372, 373, 374, 375, 376, 377, 378, 379, 380, 381, 382, 383, 384, 385, 386, 387, 388, 389, 390, 391, 392, 393, 394, 395, 396, 397, 398, 399, 400, 401, 402, 403, 404, 405, 406, 407, 408, 409, 410, 411, 412, 413, 414, 415, 416, 417, 418, 419, 420, 421, 422, 423, 424, 425, 426, 427, 428, 429, 430, 431, 432, 433, 434, 435, 436, 437, 438, 439, 440, 441, 442, 443, 444, 445, 446, 447, 448, 449, 450, 451, 452, 453, 454, 455, 456, 457, 458, 459, 460, 461, 462, 463, 464, 465, 466, 467, 468, 469, 470, 471, 472, 473, 474, 475, 476, 477, 478, 479, 480, 481, 482, 483, 484, 485, 486, 487, 488, 489, 490, 491, 492, 493, 494, 495, 496, 497, 498, 499, 500 methylation sites of Table 29. Analyses of each and every specific combination of the methylation sites of Table 29 are contemplated herein. It is specifically contemplated that any one or more of the methylation sites of Table 29 may be excluded in embodiments described herein. In some embodiments, SCLC-P is identified based on detection of differential methylation of cg27232389, cg03020852, cg11691710, cg14197123, cg17885507, cg03517570, cg13297671, cg18795320, cg03075214, cg06832246, cg05683632, cg00704369, cg22171098, cg09934399, cg02817764, cg24677222, cg16770048, cg14701925, cg04182076, cg18969798, cg03803789, cg13240089, cg17758792, cg06923861, cg07956003, cg08275278, cg04983681, cg17728697, cg09472222, cg02220284, cg05366160, cg13705753, cg06839854, cg02675973, cg05395645, cg25601286, cg11701604, cg07825782, cg00600617, cg16054907, cg01489441, cg15564226, cg10026427, cg01149239, cg04479757, cg11019743, cg13207778, cg25296465, cg03387092, cg14175330, cg05999426, cg19011089, cg14313328, cg18529415, cg04563108, cg25874150, cg16318349, cg13081156, cg14088354, cg03264729, cg01580044, cg07313835, cg11597418, cg26855672, cg03356778, cg05216984, cg02593168, cg20314331, cg26797073, cg15873449, cg18983310, cg08265811, cg22340762, cg00618183, cg12452539, cg15786168, cg06669752, cg24136932, cg24272324, cg04619304, cg01772824, cg13921012, cg06542565, cg10288437, cg10609655, cg07262682, cg21289124, cg07325342, cg14211075, cg00719067, cg05554594, cg08368885, and/or cg21876001. In some embodiments, SCLC-P is identified based on detection of differential methylation of chr1:11032833, chr1:15207848, chr1:15945017, chr1:17026179, chr1:25741499, chr1:27551002, chr1:32327585, chr1:42682988, chr1:52365896, chr1:56552275, chr1:116407596, chr1:147829076, chr1:156538486, chr1:156750879, chr1:164576909, chr1:197915932, chr1:204289083, chr1:204571233, chr1:212618744, chr1:212618752, chr1:212638013, chr1:231162869, chr1:231162872, chr1:231162880, chr10:14365352, chr10:55631088, chr10:55631097, chr10:97713353, chr10:97713362, chr10:123017613, chr11:63997490, chr11:65536690, chr11:75410397, chr11:77750252, chr11:126313324, chr12:433809, chr12:7291128, chr12:57128650, chr12:67389978, chr12:75861004, chr12:81759542, chr12:85489437, chr12:101309330, chr12:103993054, chr12:104599362, chr12:104599370, chr12:105977083, chr12:110245057, chr12:110245058, chr12:110245093, chr12:111841988, chr12:120456258, chr12:122032753, chr12:122032775, chr12:124497504, chr12:124524949, chr12:124631301, chr13:20345144, chr14:89701670, chr14:105392906, chr14:105392911, chr15:43746172, chr15:58701617, chr15:74789232, chr15:74789276, chr15:74789281, chr16:234790, chr16:234826, chr16:648840, chr16:1498961, chr16:1746192, chr16:2075993, chr16:2964040, chr16:4767447, chr16:8621572, chr16:28193303, chr16:28863649, chr16:29906931, chr16:30125736, chr16:30973692, chr16:66696829, chr16:68341637, chr16:85611879, chr17:21665928, chr17:29576080, chr17:34252590, chr17:43187274, chr17:48932449, chr17:49816143, chr17:63383824, chr17:63383830, chr17:63739476, chr17:64661931, chr17:68205724, chr17:72165644, chr17:76420086, chr17:77439476, chr17:77439513, chr17:81248481, chr17:81248517, chr18:5543758, chr18:5543760, chr18:5543767, chr18:5543774, chr18:14907472, chr18:28175723, chr18:28175730, chr18:28175734, chr18:28175743, chr18:57574427, chr19:807444, chr19:811705, chr19:991153, chr19:991161, chr19:1633524, chr19:1993008, chr19:2115209, chr19:5618219, chr19:11483864, chr19:11483872, chr19:11483877, chr19:11483882, chr19:11483887, chr19:11483902, chr19:11483907, chr19:11483912, chr19:14206288, chr19:14559510, chr19:16628375, chr19:17209718, chr19:17209725, chr19:17209733, chr19:17209752, chr19:18778224, chr19:35721194, chr19:35944911, chr19:38907710, chr19:42211188, chr19:45712682, chr19:49464557, chr19:49881697, chr19:55284281, chr19:55615832, chr2:9003857, chr2:61166980, chr2:89848744, chr2:190440760, chr2:200981406, chr2:202250239, chr2:209772183, chr2:224690031, chr20:1185694, chr20:62122215, chr20:62309811, chr20:62328882, chr20:63667368, chr21:5137123, chr21:25735328, chr21:41879374, chr21:43882191, chr21:45277832, chr22:31098838, chr22:33058579, chr22:40026246, chr22:49884754, chr3:13366052, chr3:112523580, chr3:112523614, chr3:128428346, chr3:138798882, chr3:150408978, chr3:157067444, chr3:165348114, chr3:165348116, chr3:186783828, chr3:197297920, chr4:1229607, chr4:4438102, chr5:3750940, chr5:6615113, chr5:16179849, chr5:16179857, chr5:16179865, chr5:16179878, chr5:16179881, chr5:16179883, chr5:16180008, chr5:178204129, chr5:178204131, chr6:3577167, chr6:27279630, chr6:73310426, chr6:73310429, chr6:73310454, chr6:73310463, chr6:125791186, chr6:136290429, chr7:996193, chr7:1551166, chr7:1849861, chr7:1854236, chr7:4730195, chr7:5070131, chr7:6333296, chr7:15848453, chr7:26247657, chr7:29643153, chr7:30043812, chr7:43877706, chr7:44146254, chr7:44748739, chr7:149022546, chr8:31640044, chr8:31640053, chr8:31640067, chr8:42842942, chr8:80578027, chr9:107245787, chr9:120913537, chr9:126408197, chr9:131584010, chr9:136197462, chr9:136451036, chr9:136451222, chr9:136451519, chr9:137013461, chr9:137013470, chr9:137013473, chr9:137013486, chr9:137278360, chr9:137278384, chr9:137278402, chr9:137278488, chrX:150899022, chr6:34553001, chr12:118980854, chr19:811773, chr2:130345606, chr2:202250236, chr7:1005784, chr19:7934275, chr14:34024477, chr7:107390004, chr1:25216043, chr15:85610808, chr19:5668214, chr7:5297184, chr1:241356405, chr10:102714534, chr8:31640064, chr12:120967099, chr19:1393965, chr15:25438570, chr15:74789270, chr7:5297124, chr8:123443315, chr1:180269892, chr19:1456332, chr16:73028748, chr2:75056446, chr19:18543346, chr2:75056435, chr2:75056445, chr16:29876586, chr6:43771035, chr12:124344199, chr8:139649190, chr2:230068915, chr1:6461087, chr1:234661304, chr12:7824990, chr16:71931876, chr21:36736273, chr3:183636771, chr5:143405413, chr10:69402478, chr14:104887313, chr16:1315523, chr7:2295681, chr1:214108494, chr1:236064214, chr2:44168465, chr2:114662163, chr3:107999730, chr6:3577155, chr6:3577177, chr7:57818168, chr1:41324219, chr1:213051051, chr11:4521815, chr12:43552603, chr17:35488134, chr3:14401986, chr6:13450944, chr9:101738883, chr1:167221470, chr16:88880826, chr19:3652127, chr20:17396399, chr12:104599364, chr16:87827109, chr19:17873403, chr19:17873409, chr19:17873411, chr6:63656136, chr12:45216305, chr12:57837371, chr16:21557088, chr17:34331252, chr21:39054428, chr7:3910633, chr16:3655081, chr18:12324746, chr9:76701152, chr19:1648427, chr20:47468584, chr3:96841981, chr1:239386481, chr19:3088153, chr20:17396185, chr6:27557116, chr6:55680614, chr7:5297111, chr19:58440360, chr7:151111578, chr8:139649329, chr19:28520192, chr6:34778112, chr9:131112163, chr7:102201787, chr8:42153025, chr8:42622755, chr1:154174789, chr17:49816136, chr19:7934266, chr19:13207507, chr2:17317571, chr5:3754702, chr6:24626028, chr6:44653805, chr2:173307231, chr6:22509101, chr8:107889762, chr5:128879466, chr19:3094373, chr17:72235698, chr21:34510358, chr9:137013468, chr9:137013480, chr1:220001751, chr5:308909, chr1:155544582, chr1:204089544, chr11:107970310, chr12:95066688, chr19:16553992, chr5:16179995, chr5:16180003, chr5:25900907, chr8:35235230, chr16:28617820, chr17:76419894, chr19:48194427, chr7:14695759, chr1:6470978, chr1:23636028, chr20:350196, chr1:31193833, chr8:126862783, chr11:78046094, chr12:132528585, chr18:79375872, chr19:652099, chr21:9873175, chr7:57821358, chr7:101967581, chr8:144107705, chr12:62602516, chr1:6460819, chr1:244198034, chr19:5704451, chr9:137278356, chr10:76887333, chr19:1433766, chr19:13830675, chr20:37985816, chr1:15945048, chr14:23078131, chr9:133459357, chr8:31640070, chr12:62799867, chr5:32446706, chr12:120967103, chr5:128879583, chr15:69087040, chr20:347269, chr9:132325224, chr16:78195948, chr19:28824412, chr19:44753544, chr22:11288465, chr17:72123931, chr17:72124220, chr17:72124238, chr2:36973823, chr5:16179886, chr20:44560834, chr12:50057840, chr19:1456317, chr7:1421100, chr8:123443370, chr17:82626176, chr18:63283742, chr11:65650576, chr12:31591065, chr16:73028716, chr6:106135145, chr1:230399219, chr17:80599748, chr3:136614019, chr9:93826472, chr19:812407, chr6:135771171, chr9:137278500, chr16:3987194, chr17:49810078, chr2:164717792, chr22:40600900, chr3:123976907, chr3:123976934, chr2:89244905, chr19:5668194, chr11:78046073, chr9:127507984, chr9:120877473, chr1:159210159, chr6:44441882, chr8:101950035, chr1:11331701, chr19:1992998, chr19:1993003, chr9:128704978, chr9:124453638, chr19:1468243, chr16:2429260, chr20:62309824, chr7:44146237, chr8:31640050, chr9:94914976, chr12:37419025, chr12:45776142, chr17:42670166, chr19:1633551, chr9:137281710, chr1:214281447, chr6:34553086, chr1:167918494, chr17:72123590, chr19:45067160, chr6:157300486, chr7:1734991, chr7:1734996, chr1:70338695, chr19:18868002, chr9:14041343, chr10:76887324, chr19:7934351, chr19:13644740, chr2:5691280, chr5:134550960, chr12:95633568, chr1:6460956, chr16:17134583, chr16:17134595, chr16:61149835, chr19:4101376, chr19:37692212, chr6:1494847, chr7:38178231, chr7:71132295, chr11:134072686, chr16:2720277, chr16:11345580, chr17:29613358, chr18:14867181, chr19:3613344, chr2:209772188, chr6:34552991, chr6:88962788, chr12:105977085, chr17:7479367, chr17:21379559, chr19:10502839, chr19:39178093, chr21:43313606, chr22:31306646, chr3:11717633, chr3:139539693, chr7:4730228, and/or chr4:154375969, including any combination thereof.


In some embodiments, SCLC-I is identified based on detection of differential methylation at at least or at most 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127, 128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 145, 146, 147, 148, 149, 150, 151, 152, 153, 154, 155, 156, 157, 158, 159, 160, 161, 162, 163, 164, 165, 166, 167, 168, 169, 170, 171, 172, 173, 174, 175, 176, 177, 178, 179, 180, 181, 182, 183, 184, 185, 186, 187, 188, 189, 190, 191, 192, 193, 194, 195, 196, 197, 198, 199, 200, 201, 202, 203, 204, 205, 206, 207, 208, 209, 210, 211, 212, 213, 214, 215, 216, 217, 218, 219, 220, 221, 222, 223, 224, 225, 226, 227, 228, 229, 230, 231, 232, 233, 234, 235, 236, 237, 238, 239, 240, 241, 242, 243, 244, 245, 246, 247, 248, 249, 250, 251, 252, 253, 254, 255, 256, 257, 258, 259, 260, 261, 262, 263, 264, 265, 266, 267, 268, 269, 270, 271, 272, 273, 274, 275, 276, 277, 278, 279, 280, 281, 282, 283, 284, 285, 286, 287, 288, 289, 290, 291, 292, 293, 294, 295, 296, 297, 298, 299, 300, 301, 302, 303, 304, 305, 306, 307, 308, 309, 310, 311, 312, 313, 314, 315, 316, 317, 318, 319, 320, 321, 322, 323, 324, 325, 326, 327, 328, 329, 330, 331, 332, 333, 334, 335, 336, 337, 338, 339, 340, 341, 342, 343, 344, 345, 346, 347, 348, 349, 350, 351, 352, 353, 354, 355, 356, 357, 358, 359, 360, 361, 362, 363, 364, 365, 366, 367, 368, 369, 370, 371, 372, 373, 374, 375, 376, 377, 378, 379, 380, 381, 382, 383, 384, 385, 386, 387, 388, 389, 390, 391, 392, 393, 394, 395, 396, 397, 398, 399, 400, 401, 402, 403, 404, 405, 406, 407, 408, 409, 410, 411, 412, 413, 414, 415, 416, 417, 418, 419, 420, 421, 422, 423, 424, 425, 426, 427, 428, 429, 430, 431, 432, 433, 434, 435, 436, 437, 438, 439, 440, 441, 442, 443, 444, 445, 446, 447, 448, 449, 450, 451, 452, 453, 454, 455, 456, 457, 458, 459, 460, 461, 462, 463, 464, 465, 466, 467, 468, 469, 470, 471, 472, 473, 474, 475, 476, 477, 478, 479, 480, 481, 482, 483, 484, 485, 486, 487, 488, 489, 490, 491, 492, 493, 494, 495, 496, 497, 498, 499, 500, 501, 502, 503, 504, 505, 506, 507, 508, 509, 510, 511, 512, 513, 514, 515, 516, 517, 518, 519, 520, 521, 522, 523, 524, 525, 526, 527, 528, 529, 530, 531, 532, 533, 534, 535, 536, 537, 538, 539, 540, 541, 542, 543, 544, 545, 546, 547, 548, 549, 550, 551, 552, 553, 554, 555, 556, 557, 558, 559, 560, 561, 562, 563, 564, 565, 566, 567, 568, 569, 570, 571, 572, 600, 700, 800, 900, or 1000 methylation sites of Table 5. Analyses of each and every specific combination of the methylation sites of Table 5 are contemplated herein. It is specifically contemplated that any one or more of the methylation sites of Table 5 may be excluded in embodiments described herein. In some embodiments, SCLC-I is identified based on detection of differential methylation at at least or at most 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, or 44 methylation sites of Table 10. Analyses of each and every specific combination of the methylation sites of Table 10 are contemplated herein. It is specifically contemplated that any one or more of the methylation sites of Table 10 may be excluded in embodiments described herein. In some embodiments, SCLC-I is identified based on detection of differential methylation at at least or at most 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30 methylation sites of Table 18. Analyses of each and every specific combination of the methylation sites of Table 18 are contemplated herein. It is specifically contemplated that any one or more of the methylation sites of Table 18 may be excluded in embodiments described herein. In some embodiments, SCLC-I is identified based on detection of differential methylation at at least or at most 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127, 128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 145, 146, 147, 148, 149, 150, 151, 152, 153, 154, 155, 156, 157, 158, 159, 160, 161, 162, 163, 164, 165, 166, 167, 168, 169, 170, 171, 172, 173, 174, 175, 176, 177, 178, 179, 180, 181, 182, 183, 184, 185, 186, 187, 188, 189, 190, 191, 192, 193, 194, 195, 196, 197, 198, 199, 200, 201, 202, 203, 204, 205, 206, 207, 208, 209, 210, 211, 212, 213, 214, 215, 216, 217, 218, 219, 220, 221, 222, 223, 224, 225, 226, 227, 228, 229, 230, 231, 232, 233, 234, 235, 236, 237, 238, 239, 240, 241, 242, 243, 244, 245, 246, 247, 248, 249, 250, 251, 252, 253, 254, 255, 256, 257, 258, 259, 260, 261, 262, 263, 264, 265, 266, 267, 268, 269, 270, 271, 272, 273, 274, 275, 276, 277, 278, 279, 280, 281, 282, 283, 284, 285, 286, 287, 288, 289, 290, 291, 292, 293, 294, 295, 296, 297, 298, 299, 300, 301, 302, 303, 304, 305, 306, 307, 308, 309, 310, 311, 312, 313, 314, 315, 316, 317, 318, 319, 320, 321, 322, 323, 324, 325, 326, 327, 328, 329, 330, 331, 332, 333, 334, 335, 336, 337, 338, 339, 340, 341, 342, 343, 344, 345, 346, 347, 348, 349, 350, 351, 352, 353, 354, 355, 356, 357, 358, 359, 360, 361, 362, 363, 364, 365, 366, 367, 368, 369, 370, 371, 372, 373, 374, 375, 376, 377, 378, 379, 380, 381, 382, 383, 384, 385, 386, 387, 388, 389, 390, 391, 392, 393, 394, 395, 396, 397, 398, 399, 400, 401, 402, 403, 404, 405, 406, 407, 408, 409, 410, 411, 412, 413, 414, 415, 416, 417, 418, 419, 420, 421, 422, 423, 424, 425, 426, 427, 428, 429, 430, 431, 432, 433, 434, 435, 436, 437, 438, 439, 440, 441, 442, 443, 444, 445, 446, 447, 448, 449, 450, 451, 452, 453, 454, 455, 456, 457, 458, 459, 460, 461, 462, 463, 464, 465, 466, 467, 468, 469, 470, 471, 472, 473, 474, 475, 476, 477, 478, 479, 480, 481, 482, 483, 484, 485, 486, 487, 488, 489, 490, 491, 492, 493, 494, 495, 496, 497, 498, 499, 500, 501, 502, 503, 504, 505, 506, 507, 508, 509, 510, 511, 512, 513, 514, 515, 516, 517, 518, 519, 520, 521, 522, 523, 524, 525, 526, 527, 528, 529, 530, 531, 532, 533, 534, 535, 536, 537, 538, 539, 540, 541, 542, 543, 544, 545, 546, 547, 548, 549, 550, 551, 552, 553, 554, 555, 556, 557, 558, 559, 560, 561, 562, 563, 564, 565, 566, 567, 568, 569, 570, 571, 572, 600, 700, 800, or 848 methylation sites of Table 23. Analyses of each and every specific combination of the methylation sites of Table 23 are contemplated herein. It is specifically contemplated that any one or more of the methylation sites of Table 23 may be excluded in embodiments described herein. In some embodiments, SCLC-I is identified based on detection of differential methylation at at least or at most 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127, 128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 145, 146, 147, 148, 149, 150, 151, 152, 153, 154, 155, 156, 157, 158, 159, 160, 161, 162, 163, 164, 165, 166, 167, 168, 169, 170, 171, 172, 173, 174, 175, 176, 177, 178, 179, 180, 181, 182, 183, 184, 185, 186, 187, 188, 189, 190, 191, 192, 193, 194, 195, 196, 197, 198, 199, 200, 201, 202, 203, 204, 205, 206, 207, 208, 209, 210, 211, 212, 213, 214, 215, 216, 217, 218, 219, 220, 221, 222, 223, 224, 225, 226, 227, 228, 229, 230, 231, 232, 233, 234, 235, 236, 237, 238, 239, 240, 241, 242, 243, 244, 245, 246, 247, 248, 249, 250, 251, 252, 253, 254, 255, 256, 257, 258, 259, 260, 261, 262, 263, 264, 265, 266, 267, 268, 269, 270, 271, 272, 273, 274, 275, 276, 277, 278, 279, 280, 281, 282, 283, 284, 285, 286, 287, 288, 289, 290, 291, 292, 293, 294, 295, 296, 297, 298, 299, 300, 301, 302, 303, 304, 305, 306, 307, 308, 309, 310, 311, 312, 313, 314, 315, 316, 317, 318, 319, 320, 321, 322, 323, 324, 325, 326, 327, 328, 329, 330, 331, 332, 333, 334, 335, 336, 337, 338, 339, 340, 341, 342, 343, 344, 345, 346, 347, 348, 349, 350, 351, 352, 353, 354, 355, 356, 357, 358, 359, 360, 361, 362, 363, 364, 365, 366, 367, 368, 369, 370, 371, 372, 373, 374, 375, 376, 377, 378, 379, 380, 381, 382, 383, 384, 385, 386, 387, 388, 389, 390, 391, 392, 393, 394, 395, 396, 397, 398, 399, 400, 401, 402, 403, 404, 405, 406, 407, 408, 409, 410, 411, 412, 413, 414, 415, 416, 417, 418, 419, 420, 421, 422, 423, 424, 425, 426, 427, 428, 429, 430, 431, 432, 433, 434, 435, 436, 437, 438, 439, 440, 441, 442, 443, 444, 445, 446, 447, 448, 449, 450, 451, 452, 453, 454, 455, 456, 457, 458, 459, 460, 461, 462, 463, 464, 465, 466, 467, 468, 469, 470, 471, 472, 473, 474, 475, 476, 477, 478, 479, 480, 481, 482, 483, 484, 485, 486, 487, 488, 489, 490, 491, 492, 493, 494, 495, 496, 497, 498, 499, 500 methylation sites of Table 30. Analyses of each and every specific combination of the methylation sites of Table 30 are contemplated herein. It is specifically contemplated that any one or more of the methylation sites of Table 30 may be excluded in embodiments described herein. In some embodiments, SCLC-I is identified based on detection of differential methylation of cg09248054, cg02379560, cg04917391, cg05020685, cg06485940, cg16364495, cg05857126, cg13780782, cg02008691, cg24664798, cg17265693, cg06508056, cg15932065, cg16405211, cg18804920, cg23889772, cg07270851, cg24238564, cg03850035, cg02659920, cg05651265, cg10976861, cg24127874, cg02365303, cg11799006, cg00336977, cg02125259, cg09433131, cg14865862, cg20136513, cg00378510, cg06473097, cg23844705, cg19741167, cg16769791, cg00448761, cg04303901, cg13077545, cg15559684, cg07035875, cg19115272, cg06093379, cg19154027, and/or cg22073838. In some embodiments, SCLC-I is identified based on detection of differential methylation of chr1:1040462, chr1:1040475, chr1:1682754, chr1:6249894, chr1:6249902, chr1:6249914, chr1:6249917, chr1:12191832, chr1:15741578, chr1:16980570, chr1:16980579, chr1:16980593, chr1:18630506, chr1:20487144, chr1:21574155, chr1:23801501, chr1:24730777, chr1:24730787, chr1:24730788, chr1:24730796, chr1:24730797, chr1:25195867, chr1:31065986, chr1:36323440, chr1:39491967, chr1:43285575, chr1:43285577, chr1:43369421, chr1:89843439, chr1:89843473, chr1:145960916, chr1:153532886, chr1:153532890, chr1:156908050, chr1:163404039, chr1:163423088, chr1:163423133, chr1:163423188, chr1:163423194, chr1:163423199, chr1:163546298, chr1:164136579, chr1:164136587, chr1:164136632, chr1:164236230, chr1:164236242, chr1:165235591, chr1:167796909, chr1:208601823, chr1:213771516, chr1:213820223, chr1:213861854, chr1:213861907, chr1:213910457, chr1:225962005, chr1:230322908, chr1:240992226, chr1:241128149, chr1:243916475, chr10:99431109, chr10:132518774, chr11:366066, chr11:438565, chr11:438607, chr11:726201, chr11:848890, chr11:848923, chr11:848927, chr11:848933, chr11:849115, chr11:849137, chr11:849141, chr11:849142, chr11:849148, chr11:849149, chr11:17734970, chr11:44566012, chr11:45922046, chr11:45922074, chr11:45922076, chr11:45922090, chr11:45922100, chr11:45922275, chr11:45922276, chr11:45923059, chr11:45923077, chr11:46381467, chr11:64299743, chr11:64299761, chr11:64300844, chr11:64300851, chr11:64300858, chr11:64300884, chr11:64490631, chr11:64490632, chr11:64712787, chr11:65355635, chr11:65355646, chr11:65355670, chr11:65551424, chr11:65551425, chr11:67023317, chr11:67464932, chr11:67464964, chr11:73264689, chr11:75240135, chr11:85811258, chr11:89593934, chr11:92709117, chr11:93542959, chr11:114059499, chr11:114059530, chr11:114059757, chr11:114061199, chr11:114061210, chr11:114061212, chr11:114061215, chr11:114061239, chr11:114631735, chr11:115504986, chr11:115504997, chr11:115505001, chr11:117432347, chr11:117795858, chr11:118956922, chr11:119182275, chr11:119206066, chr11:119729116, chr11:120284546, chr11:124746873, chr11:124746909, chr11:124746913, chr11:124863373, chr11:124863394, chr11:125263544, chr11:129316134, chr11:130070945, chr11:130159700, chr11:130159829, chr11:130159851, chr11:130159854, chr11:133064200, chr11:133064212, chr11:133064221, chr11:133064231, chr11:133064233, chr11:134311382, chr12:6961918, chr12:6962633, chr12:6962646, chr12:6962648, chr12:6964182, chr12:16504002, chr12:16714352, chr12:16714353, chr12:25939377, chr12:32470696, chr12:32646853, chr12:42238116, chr12:49346692, chr12:51392037, chr12:52903995, chr12:52904021, chr12:52948914, chr12:96738497, chr12:96738507, chr12:97138576, chr12:97324958, chr12:97325039, chr12:97607417, chr12:97619683, chr12:97755215, chr12:97855295, chr12:97924591, chr12:98350733, chr12:103100480, chr12:103165897, chr12:103165901, chr12:103165909, chr12:103165933, chr12:108310791, chr12:108310792, chr12:108310807, chr12:109291976, chr12:109292004, chr12:119258242, chr12:119258280, chr12:132134549, chr12:132134577, chr12:132134595, chr12:132134596, chr12:132134600, chr12:132134601, chr12:132134630, chr13:21298314, chr13:34918433, chr13:35920681, chr13:38494047, chr13:38545892, chr13:39205350, chr13:39300854, chr13:42040772, chr13:54129564, chr13:54844155, chr13:55129970, chr13:55166399, chr13:59341409, chr13:70033781, chr13:73632816, chr13:73632851, chr13:78840351, chr13:101796812, chr13:101927978, chr13:101933364, chr13:102060417, chr13:102060419, chr13:102060451, chr13:102068532, chr13:102068551, chr13:102068563, chr13:102068572, chr13:102390033, chr13:110473172, chr13:110536576, chr13:110825816, chr13:110830973, chr13:112988667, chr13:113016746, chr13:113433650, chr14:21069139, chr14:21069177, chr14:21069183, chr14:22883379, chr14:26553939, chr14:29450905, chr14:29450950, chr14:29523990, chr14:30391455, chr14:37657127, chr14:37751915, chr14:37751924, chr14:37751973, chr14:37751985, chr14:37772760, chr14:37772778, chr14:37772795, chr14:37802591, chr14:38033650, chr14:38033658, chr14:38115498, chr14:38115499, chr14:38115532, chr14:38129918, chr14:39442503, chr14:44156407, chr14:44156411, chr14:44156431, chr14:44379746, chr14:44379797, chr14:53956630, chr14:53956642, chr14:53956653, chr14:53956667, chr14:56506990, chr14:56534824, chr14:56832505, chr14:56992482, chr14:56992483, chr14:61348113, chr14:62736524, chr14:63064707, chr14:63114304, chr14:63114311, chr14:63114337, chr14:64741044, chr14:64942593, chr14:64942636, chr14:67241487, chr14:88791865, chr14:88791879, chr14:104827290, chr14:104895812, chr14:104895822, chr15:22702324, chr15:43776557, chr15:43776576, chr15:53791638, chr16:64387, chr16:561080, chr16:561087, chr16:677534, chr16:2148616, chr16:4260566, chr16:14303673, chr16:14303701, chr16:14303702, chr16:14303720, chr16:19522006, chr16:52395111, chr16:52395146, chr16:52504927, chr16:52504937, chr16:52504992, chr16:52621872, chr16:56191818, chr16:58500253, chr16:58500281, chr16:58500286, chr16:67666791, chr16:67666821, chr16:67666825, chr16:67666999, chr16:67667017, chr16:67667021, chr16:71626053, chr16:84312964, chr16:84312972, chr16:84312978, chr16:84519935, chr16:84659693, chr16:84842521, chr16:85449391, chr16:85449403, chr16:85449420, chr16:86467633, chr16:88291496, chr16:88302508, chr16:88737568, chr17:4263552, chr17:4449947, chr17:7044006, chr17:17403801, chr17:17403831, chr17:19379152, chr17:19379174, chr17:19379191, chr17:29176890, chr17:29565877, chr17:29565896, chr17:29565920, chr17:31561710, chr17:41527810, chr17:42951031, chr17:43720600, chr17:48892861, chr17:65625809, chr17:68870337, chr17:74213330, chr17:74961013, chr17:74961036, chr17:74972136, chr17:79794767, chr17:81397114, chr17:81397126, chr17:81397150, chr17:81514240, chr17:81902419, chr17:81902429, chr17:81902430, chr17:81902433, chr17:81902434, chr17:81902440, chr17:81902441, chr18:6929505, chr18:7327489, chr18:7327495, chr18:32928012, chr18:32928017, chr18:32928020, chr18:32928024, chr18:33167723, chr18:33167727, chr18:33225321, chr18:33317997, chr18:33318065, chr18:33570344, chr18:34609374, chr18:34639003, chr18:38714972, chr18:38714994, chr18:43102815, chr18:47748194, chr18:59148758, chr18:59148765, chr18:63207225, chr18:63207233, chr18:63207260, chr18:71409912, chr18:71652314, chr18:71652318, chr18:72662276, chr18:72677583, chr18:76446564, chr18:76446573, chr18:76446574, chr18:76446612, chr18:76472706, chr18:76580424, chr18:76590712, chr18:76590755, chr18:76590771, chr18:77020807, chr18:77132839, chr18:79334799, chr19:460731, chr19:460763, chr19:511206, chr19:511219, chr19:537165, chr19:1082036, chr19:1082073, chr19:1082079, chr19:1083180, chr19:2624624, chr19:4147445, chr19:4566632, chr19:4566647, chr19:4955146, chr19:6464556, chr19:6551811, chr19:6583884, chr19:7115981, chr19:7904264, chr19:9953412, chr19:9953424, chr19:9961699, chr19:9966503, chr19:9966579, chr19:9966586, chr19:9997385, chr19:10625441, chr19:10625699, chr19:11418683, chr19:13099153, chr19:13248768, chr19:14433259, chr19:15195814, chr19:15195823, chr19:15195830, chr19:15195831, chr19:15195838, chr19:15195844, chr19:15195847, chr19:15195851, chr19:17041847, chr19:17251851, chr19:28293220, chr19:29892627, chr19:33260980, chr19:33393584, chr19:36008846, chr19:36009562, chr19:42242259, chr19:43757320, chr19:44796859, chr19:45444316, chr19:45598430, chr19:46016118, chr19:46016119, chr19:46016123, chr19:46016124, chr19:46016125, chr19:46016126, chr19:46016130, chr19:46016136, chr19:46016138, chr19:46016139, chr19:46016142, chr19:46016144, chr19:46016145, chr19:46016146, chr19:46016147, chr19:46016148, chr19:46016149, chr19:46016465, chr19:48752569, chr19:48752624, chr19:48752637, chr19:48753115, chr19:48753117, chr19:48753159, chr19:48753363, chr19:48753390, chr19:50417522, chr19:50418925, chr19:51030848, chr19:51077450, chr19:52028350, chr19:53991315, chr19:55374611, chr19:55554857, chr2:3303753, chr2:4107720, chr2:4798818, chr2:6987052, chr2:7032109, chr2:8457740, chr2:14507507, chr2:25190664, chr2:47369968.


In some embodiments, tumor DNA from a subject is further determined to have differential methylation at one or more methylation sites of Table 13. In some embodiments, the subject is further determined to have differential methylation at at least or at most 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, or 27 methylation sites of Table 13. Analyses of each and every specific combination of the methylation sites of Table 13 are contemplated herein. It is specifically contemplated that any one or more of the methylation sites of Table 13 may be excluded in embodiments described herein. Determining tumor DNA from a subject to have differential methylation at one or more methylation sites of Table 13 may be useful in, for example, confirming that the subject has SCLC.


A treatment for the subject may be determined based on the subtype determination. Such treatment may also be in combination with another therapeutic regime, such as chemotherapy or immunotherapy. In addition, the treatment may be in combination due to a subject's cancer falling into more than one subtype, such as, for example, if one portion of the cancer cells fall into the SCLC-A subtype (e.g., express ASCL1 and/or comprise differential methylation at two or more methylation sites from Tables 2 and/or 7) and another portion of the cancer cells fall into the SCLC-N subtype (e.g., express NEUROD1 and/or comprise differential methylation at two or more methylation sites from Tables 3 and/or 8). The type and/or subtype of a given cancer may change over time, and in some embodiments the present methods regarding identifying the type and/or subtype and selecting an appropriate treatment are performed more than once, such as repeating the methods after a patient develops resistance to a selected therapy, or after a predetermined period of time, and modifying the therapy accordingly.


In some embodiments, a subject is or was determined to have a cancer of the SCLC-A subtype (e.g., determined to have differential methylation at two or more methylation sites from Tables 2, 7, 15, 20 and/or 27). In some embodiments, the subject is administered a B-cell lymphoma 2 (BCL-2) inhibitor. A BCL-2 inhibitor may describe any agent, molecule, or compound capable of inhibiting the activity of a BCL-2 family protein. Examples of BCL-2 inhibitors include ABT-737, ABT-263 (navitoclax), ABT-199 (venetoclax), GX15-070 (obatoclax), HA14-1, TW-37, AT101, and BI-97C1 (sabutoclax). In some embodiments, the BCL-2 inhibitor is ABT-737 or navitoclax. In some embodiments, the subject is administered a DLL3-targeted therapeutic. A DLL3-targeted therapeutic, as used herein, describes any agent, molecule, or compound capable of binding to a DLL3 protein and having therapeutic properties in treating cancer, including small cell lung cancer such as SCLC-A. In some embodiments, the DLL3-targeted therapeutic is an anti-DLL3 antibody or fragment thereof. In some embodiments, the DLL3-targeted therapeutic is rovalpituzumab. In some embodiments, the DLL3-targeted therapeutic is an antibody-drug conjugate. In some embodiments, the DLL3-targeted therapeutic is rovalpituzumab tesirine. In some embodiments, the DLL3-targeted therapeutic is a DLL3-targeted cellular therapy. DLL3-targeted cellular therapies include any cell-based therapeutic capable of binding to DLL3. A DLL3-targeted therapeutic may be an immune cell capable of targeting DLL3-expressing cells, for example, via expression of a DLL3-binding agent such as a DLL3-targeted chimeric antigen receptor (CAR) or T cell recept (TCR). In some embodiments, the DLL3-targeted cellular therapy is a DLL3-targeted CAR T cell. In some embodiments, the DLL3-targeted cellular therapy is a DLL3-targeted CAR NK cell.


In some embodiments, a subject is or was determined to have a cancer of the SCLC-N subtype (e.g., determined to have differential methylation at two or more methylation sites from Tables 3, 8, 16 21, and/or 28). In some embodiments, the subject is administered an Aurora kinase (AURK) inhibitor, a JAK inhibitor, or a c-Met inhibitor. In some embodiments, the subject is administered an AURK inhibitor. Examples of AURK inhibitors include alisertib, ZM447439, hesperidin, ilorasertib, VX-680, CCT 137690, lestaurtinib, NU 6140, PF 03814735, SNS 314 mesylate, TC-A 2317 hydrochloride, TAK-901, AMG-900, AS-703569, AT-9283, CYC-116, SCH-1473759, and TC-S 7010. In some embodiments, the AURK inhibitor is CYC-116, alisertib, or AS-703569. Examples of JAK inhibitors include ruxolitinib, tofacitinib, oclacitinib, baricitinib, peficitinib, fedratinib, upadacitinib, filgotinib, cerdulatinib, gandotinib, lestaurtinib, momelotinib, pacritinib, and PF-04975842. Examples of c-Met inhibitors include BMS-777607, cabozantinib, MK-2461, AMG-458, JNJ-38877605, PF-04217903, and GSK-1363089. Other drugs to which subjects having a cancer of the SCLC-N subtype may be sensitive include PF-562271, VS-507, KW-2449, pimozide, CB-64D, AC-220, omacetaxine mepasuccinate, XL-888, XL-880, ifosfamide, SL-0101, GW-5074, letrozole, CYC-202, and BIM-46187.


In some embodiments, a subject is or was determined to have a cancer of the SCLC-P subtype (e.g., determined to have differential methylation at two or more methylation sites from Tables 4, 9, 17, 22, and/or 29). In some embodiments, the subject is administered a PARP inhibitor, an AKT inhibitor, a Sky inhibitor, a JAK inhibitor, a SRC inhibitor, a BET inhibitor, an ERK inhibitor, an mTor inhibitor, an HSP90 inhibitor, a PI3K inhibitor, a CDK inhibitor, a topoisomerase inhibitor, a nucleoside analogue, an anti-metabolite, or a platinum-containing chemotherapeutic agent. Examples of PARP inhibitors include olaparib, rucaparib, niraparib, talazoparib, veliparib, pamiparib, CEP 9722, E7016, iniparib, AZD2461, and 3-aminobenzamide. In some embodiments, the PARP inhibitor is talazoparib, olaparib, niraparib, AZD-2461, or rucaparib. Examples of AKT inhibitors include CCT-128930, GSK690693, MK 2206, SC79, capivasertib, ipatasertib, borussertib, uprosertib, perifosine, AZD-5363, and A-443654. Examples of Syk inhibitors include R-406, R-788 (fostamatinib), BAY 61-3606, and nilvadipine. Examples of JAK inhibitors include ruxolitinib, tofacitinib, oclacitinib, baricitinib, peficitinib, fedratinib, upadacitinib, filgotinib, cerdulatinib, gandotinib, lestaurtinib, momelotinib, pacritinib, AZD-1480, XL-019, SB-1578, WL-1034, and PF-04975842. Examples of SRC inhibitors include dasatinib, AZD-0530, KX2-391, bosutinib, saracatinib, and quercetin. Examples of BET inhibitors include GSK1210151A, GSK525762, (+)-JQ1, OTX-015, TEN-010, CPI-203, CPI-0610, LY294002, AZD5153, MT-1, and MS645. Examples of ERK inhibitors include SC-1 (pluripotin), AX 15836, BIX 02189, ERK5-IN-1, FR 180204, TCS ERK 11e, TMCB, and XMD 8-92. Examples of CDK inhibitors include R-547, palbociclib, LY-2835219, CYC-202, ribociclib, abemaciclib, and trilaciclib. Examples of mTor inhibitors include PF-04212384, OSI-027, rapamycin, AZD-2014, RG-7603, BGT-226, PI-103, GSK-2126458, everolimus, temsirolimus, ridaforolimus, sirolimus, dactolisib, and sapanisertib. Examples of anti-metabolites and nucleoside analogues include teriflunomide, pemetrexed, ONX-0801, fluorouracil, cladribine, methotrexate, mercaptopurine, gemcitabine, capecitabine, hydroxyurea, fludarabine, 2-fluoroadenosine, pralatrexate, nelarabine, cladribine, clofarabine, decitabine, azacitidine, cytarabine, floxuridine, and thioguanine. In some embodiments, the anti-metabolite is pemetrexed, methotrexate, or pralatrexate. In some embodiments, the nucleoside analog is floxuridine, cytarabine, clofarabine, or fludarabine. Examples of platinum-containing chemotherapeutic agents include cisplatin, carboplatin, oxaliplatin, nedaplatin, picoplatin, and satraplatin. In some embodiments, the platinum-containing chemotherapeutic agent is cisplatin, carboplatin, oxaliplatin, nedaplatin, picoplatin, or satraplatin. Other drugs to which patients having a cancer of the SCLC-P subtype may be sensitive include ENMD-2076, HPI-1, CP-868596, TL-32711, FGF inhibitor, AS-703569, vandetanib, CYC-116, KW-2499, GSK-2334470, BMS-582664, AEG-40730, ICG-001, CB-64D, SCH-1473759, MK-2461, CH-5132799, dovitinib, AM-2282, PP-242, ZSTK-474, crizotinib, apitolisib, AT-9283, MPC-3100, alisertib, LOR-253, INK-128, AZD-8055, omacetaxine mepasuccinate, everolimus, XL-888, XL-880, PF-04929113, PF-4942847, dactolisib, PF-04691502, TAK-901, CUDC-305, tretinoin, GSK-461364, BAY-80-6946, danorubicin, doxorubicin, valrubicin, YK-4-279, PF-4176340, BKM-120, APO-866, EB-1627, axitinib, XR-5944, XR-5000, BX-912, mitoxantrone, LY-294002, ixabepilone, GDC-0941, BMS-536924, 3-AP, thiotepa, belinostat, and ABT-348.


In some embodiments, a subject is or was determined to have a cancer of the SCLC-I subtype (e.g., determined to have differential methylation at two or more methylation sites from Tables 5, 10, 18, 23 and/or 30). These cells may express immune checkpoint proteins, inflammatory markers, STING pathway proteins, CCL5, CXCL10, MHC proteins, CD274 (PD-L1), LAG3, C10orf54 (VISTA), IDO1, CD38, and ICOS. In this case, the patient is selected for treatment with an immune checkpoint inhibitor, a BTK inhibitor, a Syk inhibitor, a multikinase inhibitor, an ERK inhibitor, an VEGFR inhibitor, a MEK inhibitor, and/or a FGFR inhibitor. Examples of BTK inhibitors include ibrutinib, LCB 03-0110, LFM-A13, PCI 29732, PF 06465469, and terreic acid. Examples of Syk inhibitors include R-406, R-788 (fostamatinib), BAY 61-3606, and nilvadipine. Examples of multikinase inhibitors include LY-2801653, ENMD-2076, ponatinib, and pazopanib. Examples of ERK inhibitors include SC-1 (pluripotin), AX 15836, BIX 02189, ERK5-IN-1, FR 180204, TCS ERK Ile, TMCB, and XMD 8-92. Examples of VEGFR inhibitors include ASP-4130 (tivozanib), lenvatinib, RG-7167, sorafenib, sunitinib, bevacizumab, cabozantinib, regorafenib, nintedanib, and apatinib. Examples of MEK inhibitors include RO-5126766, AZD-8330, TAK-733, XL-518, PD-0325901, ARRY-162, trametinib, pimasertib, cobimetinib, binimetinib, and selumetinib. Examples of FGFR inhibitors include AZD-4547, PD-173074, LY-2874455, BGJ-398, ponatinib, nintedanib, dovitinib, danusertib, and brivanib. Other drugs to which patients having a cancer of the SCLC-I subtype may be sensitive include AZD-1480, AZD-0530, ASP-3026, fulvestrant, SCH-1473759, MK-2461, LY-2090314, PP-242, 17-AAG, BPR1J-097, INK-128, AZD-8055, omacetaxine mepasuccinate, everolimus, XL-888. XL-880, dactolisib, PF-04691502. OSI-027, rapamycin, CUDC-305, and bleomycin.


II. Classification

Aspects of the present disclosure are directed to methods for classification of a subject as having a small cell lung cancer (SCLC) of one of four subtypes: SCLC-A, SCLC-N, SCLC-P, or SCLC-I. In some embodiments, the subject is classified as having SCLC-A, SCLC-N, SCLC-P, or SCLC-I based, at least in part, on determining a methylation status of two or more methylation sites of Tables 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 26, 27, 28, 29, and/or 30. In some embodiments, the subject is classified as having SCLC-A, SCLC-N, SCLC-P, or SCLC-I based on determining a methylation status of at least or at most 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127, 128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 145, 146, 147, 148, 149, 150, 151, 152, 153, 154, 155, 156, 157, 158, 159, 160, 161, 162, 163, 164, 165, 166, 167, 168, 169, 170, 171, 172, 173, 174, 175, 176, 177, 178, 179, 180, 181, 182, 183, 184, 185, 186, 187, 188, 189, 190, 191, 192, 193, 194, 195, 196, 197, 198, 199, 200, 201, 202, 203, 204, 205, 206, 207, 208, 209, 210, 211, 212, 213, 214, 215, 216, 217, 218, 219, 220, 221, 222, 223, 224, 225, 226, 227, 228, 229, 230, 231, 232, 233, 234, 235, 236, 237, 238, 239, 240, 241, 242, 243, 244, 245, 246, 247, 248, 249, 250, 251, 252, 253, 254, 255, 256, 257, 258, 259, 260, 261, 262, 263, 264, 265, 266, 267, 268, 269, 270, 271, 272, 273, 274, 275, 276, 277, 278, 279, 280, 281, 282, 283, 284, 285, 286, 287, 288, 289, 290, 291, 292, 293, 294, 295, 296, 297, 298, 299, 300, 301, 302, 303, 304, 305, 306, 307, 308, 309, 310, 311, 312, 313, 314, 315, 316, 317, 318, 319, 320, 321, 322, 323, 324, 325, 326, 327, 328, 329, 330, 331, 332, 333, 334, 335, 336, 337, 338, 339, 340, 341, 342, 343, 344, 345, 346, 347, 348, 349, 350, 351, 352, 353, 354, 355, 356, 357, 358, 359, 360, 361, 362, 363, 364, 365, 366, 367, 368, 369, 370, 371, 372, 373, 374, 375, 376, 377, 378, 379, 380, 381, 382, 383, 384, 385, 386, 387, 388, 389, 390, 391, 392, 393, 394, 395, 396, 397, 398, 399, 400, 401, 402, 403, 404, 405, 406, 407, 408, 409, 410, 411, 412, 413, 414, 415, 416, 417, 418, 419, 420, 421, 422, 423, 424, 425, 426, 427, 428, 429, 430, 431, 432, 433, 434, 435, 436, 437, 438, 439, 440, 441, 442, 443, 444, 445, 446, 447, 448, 449, 450, 451, 452, 453, 454, 455, 456, 457, 458, 459, 460, 461, 462, 463, 464, 465, 466, 467, 468, 469, 470, 471, 472, 473, 474, 475, 476, 477, 478, 479, 480, 481, 482, 483, 484, 485, 486, 487, 488, 489, 490, 491, 492, 493, 494, 495, 496, 497, 498, 499, 500, 501, 502, 503, 504, 505, 506, 507, 508, 509, 510, 511, 512, 513, 514, 515, 516, 517, 518, 519, 520, 521, 522, 523, 524, 525, 526, 527, 528, 529, 530, 531, 532, 533, 534, 535, 536, 537, 538, 539, 540, 541, 542, 543, 544, 545, 546, 547, 548, 549, 550, 551, 552, 553, 554, 555, 556, 557, 558, 559, 560, 561, 562, 563, 564, 565, 566, 567, 568, 569, 570, 571, 572, 600, 700, 800, 900, or 1000 methylation sites of Table 1, Table 20, Table 21, Table 22, Table 23, Table 27, Table 28, Table 29, or Table 30.


In some embodiments, a subject is classified as having SCLC-A. In some embodiments, a subject is classified as having SCLC-A based on detection of differential methylation at at least or at most 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127, 128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 145, 146, 147, 148, 149, 150, 151, 152, 153, 154, 155, 156, 157, 158, 159, 160, 161, 162, 163, 164, 165, 166, 167, 168, 169, 170, 171, 172, 173, 174, 175, 176, 177, 178, 179, 180, 181, 182, 183, 184, 185, 186, 187, 188, 189, 190, 191, 192, 193, 194, 195, 196, 197, 198, 199, 200, 201, 202, 203, 204, 205, 206, 207, 208, 209, 210, 211, 212, 213, 214, 215, 216, 217, 218, 219, 220, 221, 222, 223, 224, 225, 226, 227, 228, 229, 230, 231, 232, 233, 234, 235, 236, 237, 238, 239, 240, 241, 242, 243, 244, 245, 246, 247, 248, 249, 250, 251, 252, 253, 254, 255, 256, 257, 258, 259, 260, 261, 262, 263, 264, 265, 266, 267, 268, 269, 270, 271, 272, 273, 274, 275, 276, 277, 278, 279, 280, 281, 282, 283, 284, 285, 286, 287, 288, 289, 290, 291, 292, 293, 294, 295, 296, 297, 298, 299, 300, 301, 302, 303, 304, 305, 306, 307, 308, 309, 310, 311, 312, 313, 314, 315, 316, 317, 318, 319, 320, 321, 322, 323, 324, 325, 326, 327, 328, 329, 330, 331, 332, 333, 334, 335, 336, 337, 338, 339, 340, 341, 342, 343, 344, 345, 346, 347, 348, 349, 350, 351, 352, 353, 354, 355, 356, 357, 358, 359, 360, 361, 362, 363, 364, 365, 366, 367, 368, 369, 370, 371, 372, 373, 374, 375, 376, 377, 378, 379, 380, 381, 382, 383, 384, 385, 386, 387, 388, 389, 390, 391, 392, 393, 394, 395, 396, 397, 398, 399, 400, 401, 402, 403, 404, 405, 406, 407, 408, 409, 410, 411, 412, 413, 414, 415, 416, 417, 418, 419, 420, 421, 422, 423, 424, 425, 426, 427, 428, 429, 430, 431, 432, 433, 434, 435, 436, 437, 438, 439, 440, 441, 442, 443, 444, 445, 446, 447, 448, 449, 450, 451, 452, 453, 454, 455, 456, 457, 458, 459, 460, 461, 462, 463, 464, 465, 466, 467, 468, 469, 470, 471, 472, 473, 474, 475, 476, 477, 478, 479, 480, 481, 482, 483, 484, 485, 486, 487, 488, 489, 490, 491, 492, 493, 494, 495, 496, 497, 498, 499, 500, 501, 502, 503, 504, 505, 506, 507, 508, 509, 510, 511, 512, 513, 514, 515, 516, 517, 518, 519, 520, 521, 522, 523, 524, 525, 526, 527, 528, 529, 530, 531, 532, 533, 534, 535, 536, 537, 538, 539, 540, 541, 542, 543, 544, 545, 546, 547, 548, 549, 550, 551, 552, 553, 554, 555, 556, 557, 558, 559, 560, 561, 562, 563, 564, 565, 566, 567, 568, 569, 570, 571, 572, 600, 700, 800, 900, or 1000 methylation sites of Table 2. Analyses of each and every specific combination of the methylation sites of Table 2 are contemplated herein. In some embodiments, a subject is classified as having SCLC-A based on detection of differential methylation at at least or at most 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, or 30 methylation sites of Table 7. Analyses of each and every specific combination of the methylation sites of Table 7 are contemplated herein. In some embodiments, a subject is classified as having SCLC-A based on detection of differential methylation at at least or at most 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, or 30 methylation sites of Table 15. Analyses of each and every specific combination of the methylation sites of Table 15 are contemplated herein. In some embodiments, a subject is classified as having SCLC-A based on detection of differential methylation at at least or at most 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127, 128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 145, 146, 147, 148, 149, 150, 151, 152, 153, 154, 155, 156, 157, 158, 159, 160, 161, 162, 163, 164, 165, 166, 167, 168, 169, 170, 171, 172, 173, 174, 175, 176, 177, 178, 179, 180, 181, 182, 183, 184, 185, 186, 187, 188, 189, 190, 191, 192, 193, 194, 195, 196, 197, 198, 199, 200, 201, 202, 203, 204, 205, 206, 207, 208, 209, 210, 211, 212, 213, 214, 215, 216, 217, 218, 219, 220, 221, 222, 223, 224, 225, 226, 227, 228, 229, 230, 231, 232, 233, 234, 235, 236, 237, 238, 239, 240, 241, 242, 243, 244, 245, 246, 247, 248, 249, 250, 251, 252, 253, 254, 255, 256, 257, 258, 259, 260, 261, 262, 263, 264, 265, 266, 267, 268, 269, 270, 271, 272, 273, 274, 275, 276, 277, 278, 279, 280, 281, 282, 283, 284, 285, 286, 287, 288, 289, 290, 291, 292, 293, 294, 295, 296, 297, 298, 299, 300, 301, 302, 303, 304, 305, 306, 307, 308, 309, 310, 311, 312, 313, 314, 315, 316, 317, 318, 319, 320, 321, 322, 323, 324, 325, 326, 327, 328, 329, 330, 331, 332, 333, 334, 335, 336, 337, 338, 339, 340, 341, 342, 343, 344, 345, 346, 347, 348, 349, 350, 351, 352, 353, 354, 355, 356, 357, 358, 359, 360, 361, 362, 363, 364, 365, 366, 367, 368, 369, 370, 371, 372, 373, 374, 375, 376, 377, 378, 379, 380, 381, 382, 383, 384, 385, 386, 387, 388, 389, 390, 391, 392, 393, 394, 395, 396, 397, 398, 399, 400, 401, 402, 403, 404, 405, 406, 407, 408, 409, 410, 411, 412, 413, 414, 415, 416, 417, 418, 419, 420, 421, 422, 423, 424, 425, 426, 427, 428, 429, 430, 431, 432, 433, 434, 435, 436, 437, 438, 439, 440, 441, 442, 443, 444, 445, 446, 447, 448, 449, 450, 451, 452, 453, 454, 455, 456, 457, 458, 459, 460, 461, 462, 463, 464, 465, 466, 467, 468, 469, 470, 471, 472, 473, 474, 475, 476, 477, 478, 479, 480, 481, 482, 483, 484, 485, 486, 487, 488, 489, 490, 491, 492, 493, 494, 495, 496, 497, 498, 499, 500, 501, 502, 503, 504, 505, 506, 507, 508, 509, 510, 511, 512, 513, 514, 515, 516, 517, 518, 519, 520, 521, 522, 523, 524, 525, 526, 527, 528, 529, 530, 531, 532, 533, 534, 535, 536, 537, 538, 539, 540, 541, 542, 543, 544, 545, 546, 547, 548, 549, 550, 551, 552, 553, 554, 555, 556, 557, 558, 559, 560, 561, 562, 563, 564, 565, 566, 567, 568, 569, 570, 571, 572, 600, 700, 800, 900, 1000, 1100, 1200, 1300, or 1340 methylation sites of Table 20. Analyses of each and every specific combination of the methylation sites of Table 20 are contemplated herein. In some embodiments, SCLC-A is identified based on detection of differential methylation at at least or at most 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127, 128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 145, 146, 147, 148, 149, 150, 151, 152, 153, 154, 155, 156, 157, 158, 159, 160, 161, 162, 163, 164, 165, 166, 167, 168, 169, 170, 171, 172, 173, 174, 175, 176, 177, 178, 179, 180, 181, 182, 183, 184, 185, 186, 187, 188, 189, 190, 191, 192, 193, 194, 195, 196, 197, 198, 199, 200, 201, 202, 203, 204, 205, 206, 207, 208, 209, 210, 211, 212, 213, 214, 215, 216, 217, 218, 219, 220, 221, 222, 223, 224, 225, 226, 227, 228, 229, 230, 231, 232, 233, 234, 235, 236, 237, 238, 239, 240, 241, 242, 243, 244, 245, 246, 247, 248, 249, 250, 251, 252, 253, 254, 255, 256, 257, 258, 259, 260, 261, 262, 263, 264, 265, 266, 267, 268, 269, 270, 271, 272, 273, 274, 275, 276, 277, 278, 279, 280, 281, 282, 283, 284, 285, 286, 287, 288, 289, 290, 291, 292, 293, 294, 295, 296, 297, 298, 299, 300, 301, 302, 303, 304, 305, 306, 307, 308, 309, 310, 311, 312, 313, 314, 315, 316, 317, 318, 319, 320, 321, 322, 323, 324, 325, 326, 327, 328, 329, 330, 331, 332, 333, 334, 335, 336, 337, 338, 339, 340, 341, 342, 343, 344, 345, 346, 347, 348, 349, 350, 351, 352, 353, 354, 355, 356, 357, 358, 359, 360, 361, 362, 363, 364, 365, 366, 367, 368, 369, 370, 371, 372, 373, 374, 375, 376, 377, 378, 379, 380, 381, 382, 383, 384, 385, 386, 387, 388, 389, 390, 391, 392, 393, 394, 395, 396, 397, 398, 399, 400, 401, 402, 403, 404, 405, 406, 407, 408, 409, 410, 411, 412, 413, 414, 415, 416, 417, 418, 419, 420, 421, 422, 423, 424, 425, 426, 427, 428, 429, 430, 431, 432, 433, 434, 435, 436, 437, 438, 439, 440, 441, 442, 443, 444, 445, 446, 447, 448, 449, 450, 451, 452, 453, 454, 455, 456, 457, 458, 459, 460, 461, 462, 463, 464, 465, 466, 467, 468, 469, 470, 471, 472, 473, 474, 475, 476, 477, 478, 479, 480, 481, 482, 483, 484, 485, 486, 487, 488, 489, 490, 491, 492, 493, 494, 495, 496, 497, 498, 499, 500 methylation sites of Table 27. Analyses of each and every specific combination of the methylation sites of Table 27 are contemplated herein. It is specifically contemplated that any one or more of the methylation sites of Table 27 may be excluded in embodiments described herein. In some embodiments, SCLC-A is identified based on detection of differential methylation of cg00799539, cg04610718, cg10672201, cg17277939, cg11201256, cg07639982, cg01566028, cg06043710, cg01154505, cg09643186, cg03817675, cg00090674, cg02639667, cg22053861, cg14338051, cg00794178, cg16860004, cg04317756, cg01942646, cg11249931, cg08279731, cg05161074, cg00773370, cg07444408, cg08758185, cg27119612, cg22904437, cg04506569, cg04877165, and/or cg01610165. In some embodiments, SCLC-A is identified based on detection of differential methylation of chr17:74961036, chr17:74961013, chr18:59062159, chr19:13506705, chr9:134815629, chr21:41180000, chr9:93014411, chr9:114211349, chr9:134810271, chr19:3385734, chr6:51213948, chr18:27786347, chr6:168638645, chr9:134815657, chr9:134815611, chr16:84519934, chr20:20364625, chr5:172103442, chr20:22598951, chr16:85355101, chr9:134815628, chr20:20364629, chr19:511206, chr6:168149181, chr7:100122306, chr16:84519930, chr8:58989473, chr18:27786294, chr20:22557408, chr9:128177708, chr7:157633760, chr6:40349351, chr6:157229362, chr13:84927994, chr4:8101279, chr22:41667328, chr5:176843804, chr5:176529007, chr4:137426451, chr6:40349318, chr11:11578650, chr20:20364628, chr6:40349319, chr17:48190199, chr7:100122301, chr1:226589216, chr22:40022901, chr6:37078047, chr9:134765725, chr20:20364641, chr18:77020770, chr17:3695881, chr19:38253123, chr9:114255802, chr7:157017749, chr17:74823356, chr9:117355642, chr6:51213976, chr7:151045548, chr16:4537495, chr2:45274755, chr8:139674518, chr12:132134577, chr9:134885740, chr16:4537572, chr17:1961091, chr6:51213977, chr11:888785, chr9:134815626, chr13:110011941, chr19:13372294, chr16:84519955, chr20:20364626, chr20:20364640, chr17:57874806, chr6:168638634, chr7:14372215, chr22:50010360, chr14:56814573, chr13:112641259, chr7:146633722, chr7:157633743, chr21:43758530, chr6:168538915, chr5:176843791, chr2:46983311, chr2:239300749, chr7:157998148, chr6:34128215, chr13:112106712, chr16:3999700, chr9:114172063, chr9:134792142, chr11:11578688, chr7:157833048, chr1:151346323, chr21:38661697, chr1:226588954, chr20:6232329, chr9:134792130, chr9:134785070, chr9:134815627, chr9:134592825, chr16:84519980, chr7:100122290, chr11:11973687, chr19:38253193, chr14:44405368, chr16:4260161, chr2:28411073, chr1:50214861, chr16:84519943, chr22:19933408, chr11:68833022, chr7:73985377, chr9:93014375, chr9:114183920, chr16:4260632, chr9:133558991, chr6:168638701, chr7:157658598, chr19:13506729, chr19:13483181, chr16:84519942, chr11:76784947, chr11:65551424, chr7:2193699, chr5:179258981, chr14:99518884, chr18:27786301, chr11:64056580, chr6:169251928, chr9:134486435, chr12:132134595, chr16:84519935, chr21:41179996, chr14:105392911, chr7:40330569, chr13:111622152, chr2:98823202, chr17:29972557, chr9:134815918, chr1:213905614, chr7:2607131, chr4:8101234, chr12:103012503, chr14:44262090, chr6:82363058, chr9:114170339, chr6:168138608, chr12:11856447, chr19:13634667, chr9:93722421, chr9:114172123, chr17:29565848, chr11:64353390, chr9:90908530, chr16:3999757, chr11:65551425, chr9:114306707, chr19:2354863, chr9:136289024, chr6:107633714, chr7:157017791, chr6:168496984, chr3:45819148, chr18:77102188, chr12:105784446, chr17:29972550, chr11:119702010, chr5:1316124, chr7:73966925, chr3:53702765, chr11:118924054, chr19:51077543, chr17:81246338, chr12:3077928, chr12:130460997, chr7:157963798, chr12:130483815, chr7:157963771, chr14:64942593, chr18:59203056, chr19:13463517, chr20:20364646, chr7:157987469, chr2:216380208, chr20:16806905, chr17:74961041, chr3:176190636, chr20:22652824, chr6:37078083, chr14:44405319, chr18:72677631, chr9:136686592, chr2:216986073, chr2:10040203, chr21:38636406, chr9:134824994, chr12:119158214, chr7:5795946, chr22:19933350, chr9:134785048, chr13:111559772, chr16:88640994, chr17:29972549, chr6:168130574, chr6:168130602, chr9:114183394, chr9:120326115, chr3:177516507, chr7:110084403, chr22:50010361, chr18:76681573, chr7:158485004, chr21:38661630, chr15:53659351, chr19:13347369, chr19:39163809, chr17:48620272, chr18:71652249, chr6:168667391, chr10:133309889, chr1:241210311, chr19:46770637, chr20:22556743, chr2:47227055, chr7:150974698, chr20:22653042, chr14:73228468, chr19:18422970, chr21:40144935, chr16:85355024, chr19:13575256, chr9:134690692, chr6:82363052, chr7:122307220, chr7:157633801, chr1:43439683, chr16:64387, chr2:216986079, chr9:134885778, chr4:128846433, chr1:43550363, chr3:9180988, chr19:511219, chr20:62711715, chr11:47327260, chr6:51214001, chr5:10652237, chr4:6944534, chr21:38599607, chr6:168440545, chr1:18794157, chr8:52150618, chr9:133662377, chr16:4537619, chr19:39307494, chr19:55254005, chr12:130535047, chr5:82804, chr6:34128233, chr12:11856451, chr19:13506452, chr17:77452817, chr6:109290309, chr21:38661664, chr10:133309857, chr21:34667592, chr7:100477920, chr20:38294975, chr21:41648785, chr21:43758525, chr9:134822835, chr16:3728390, chr16:29604945, chr1:41727346, chr21:45032479, chr1:39954061, chr17:29972554, chr6:151809197, chr12:111287675, chr19:13463510, chr8:52150574, chr19:13014442, chr4:8164496, chr7:8417325, chr7:157673872, chr2:107461969, chr9:36781051, chr4:138912435, chr7:157594362, chr2:237733847, chr20:22652808, chr14:64942648, chr16:4260588, chr7:157603987, chr7:157540317, chr13:111515678, chr17:67488327, chr7:73990185, chr10:43849791, chr17:1961149, chr6:82585382, chr1:224184849, chr2:182053988, chr21:41508507, chr15:85942771, chr10:78139388, chr9:126420967, chr15:67806290, chr7:157963797, chr9:113593968, chr7:157875450, chr7:157875495, chr14:64942637, chr19:55254025, chr1:205447752, chr16:84519956, chr9:134797123, chr18:63207225, chr9:134772536, chr8:38495018, chr13:112107447, chr5:100864671, chr14:91418510, chr9:134768753, chr19:13245332, chr11:47327256, chr8:42275934, chr12:103165897, chr18:38714972, chr7:157824560, chr14:75978696, chr15:40873466, chr4:104663323, chr5:1316150, chr4:189096959, chr9:134750430, chr13:98405890, chr9:134825870, chr16:52621839, chr17:62653135, chr9:134881575, chr7:157633794, chr9:114170237, chr18:77020828, chr2:216840164, chr2:181684626, chr9:134819274, chr21:34743983, chr17:57874702, chr22:28923959, chr21:44698714, chr11:65551324, chr9:113593972, chr7:2193759, chr6:168440498, chr8:141264221, chr16:4260115, chr16:4537502, chr20:20365491, chr1:7491237, chr20:20364647, chr11:31893506, chr19:41704632, chr20:17068564, chr5:6543207, chr19:41323849, chr2:85733778, chr7:157685012, chr11:75240135, chr6:168315218, chr14:64633473, chr11:20056293, chr14:44379797, chr16:4537618, chr7:157864088, chr10:133309864, chr14:88256419, chr16:19425106, chr6:168355227, chr9:134765734, chr6:168453036, chr21:41490949, chr7:73989381, chr12:3077894, chr1:53462420, chr9:113593928, chr10:133309740, chr7:101666174, chr11:14974476, chr5:100944956, chr20:22557482, chr18:74782855, chr19:3656386, chr7:26397761, chr19:13463491, chr22:38087144, chr9:130535984, chr9:134892203, chr13:107429178, chr19:38253194, chr17:82078952, chr1:1174126, chr1:232307467, chr6:14499964, chr16:4260566, chr16:85286422, chr17:74006568, chr7:101707772, chr6:168496991, chr18:27786339, chr13:113793557, chr19:47209566, chr2:113325550, chr5:176529022, chr8:52150549, chr9:113594013, chr9:134490841, chr7:1620862, chr9:134179005, chr15:63053313, chr12:124617614, chr21:45032480, chr13:113723025, chr7:150945169, chr12:6961918, chr19:39307859, chr16:89948104, chr19:8153491, chr20:20365487, chr20:38294974, chr3:73790643, chr6:153237290, chr6:168130594, chr7:2524564, chr9:134785301, chr9:136367817, chr19:38253176, chr19:406561, chr1:52633297, chr9:93819344, chr11:76784948, chr14:36524358, chr13:112106739, chr6:157228665, chr7:157953525, chr10:101780858, chr12:110942244, chr6:43578006, chr2:51027486, chr7:157685871, chr21:45032448, chr21:45032452, chr7:157017829, chr11:65551413, chr7:157544388, chr6:50845964, chr5:138650055, chr1:229147368, chr9:134782536, chr9:134316337, chr12:124259764, chr11:11578685, chr20:17068489, chr20:20365493, chr22:28923940, chr22:28923966, chr1:153536136, chr9:93861253, chr11:64540473, chr2:229672283, chr7:157633759, chr9:134534796, chr9:114170276, chr19:5950505, chr1:32885121, chr12:6962651, chr18:27786338, chr18:63207261, chr19:41704681, chr8:141289585, chr11:124895535, chr17:57874844, chr11:75335191, chr18:71337086, chr2:46983412, chr1:212589163, chr20:48751499, chr4:78056611, chr3:176814702, chr17:81246299, chr2:3940818, chr12:98238503, chr9:114170300, chr11:924647, chr19:55254024, chr2:208703401, and/or chr20:22598941, including any combination thereof.


In some embodiments, a subject is classified as having SCLC-N. In some embodiments, a subject is classified as having SCLC-N based on detection of differential methylation at at least or at most 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127, 128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 145, 146, 147, 148, 149, 150, 151, 152, 153, 154, 155, 156, 157, 158, 159, 160, 161, 162, 163, 164, 165, 166, 167, 168, 169, 170, 171, 172, 173, 174, 175, 176, 177, 178, 179, 180, 181, 182, 183, 184, 185, 186, 187, 188, 189, 190, 191, 192, 193, 194, 195, 196, 197, 198, 199, 200, 201, 202, 203, 204, 205, 206, 207, 208, 209, 210, 211, 212, 213, 214, 215, 216, 217, 218, 219, 220, 221, 222, 223, 224, 225, 226, 227, 228, 229, 230, 231, 232, 233, 234, 235, 236, 237, 238, 239, 240, 241, 242, 243, 244, 245, 246, 247, 248, 249, 250, 251, 252, 253, 254, 255, 256, 257, 258, 259, 260, 261, 262, 263, 264, 265, 266, 267, 268, 269, 270, 271, 272, 273, 274, 275, 276, 277, 278, 279, 280, 281, 282, 283, 284, 285, 286, 287, 288, 289, 290, 291, 292, 293, 294, 295, 296, 297, 298, 299, 300, 301, 302, 303, 304, 305, 306, 307, 308, 309, 310, 311, 312, 313, 314, 315, 316, 317, 318, 319, 320, 321, 322, 323, 324, 325, 326, 327, 328, 329, 330, 331, 332, 333, 334, 335, 336, 337, 338, 339, 340, 341, 342, 343, 344, 345, 346, 347, 348, 349, 350, 351, 352, 353, 354, 355, 356, 357, 358, 359, 360, 361, 362, 363, 364, 365, 366, 367, 368, 369, 370, 371, 372, 373, 374, 375, 376, 377, 378, 379, 380, 381, 382, 383, 384, 385, 386, 387, 388, 389, 390, 391, 392, 393, 394, 395, 396, 397, 398, 399, 400, 401, 402, 403, 404, 405, 406, 407, 408, 409, 410, 411, 412, 413, 414, 415, 416, 417, 418, 419, 420, 421, 422, 423, 424, 425, 426, 427, 428, 429, 430, 431, 432, 433, 434, 435, 436, 437, 438, 439, 440, 441, 442, 443, 444, 445, 446, 447, 448, 449, 450, 451, 452, 453, 454, 455, 456, 457, 458, 459, 460, 461, 462, 463, 464, 465, 466, 467, 468, 469, 470, 471, 472, 473, 474, 475, 476, 477, 478, 479, 480, 481, 482, 483, 484, 485, 486, 487, 488, 489, 490, 491, 492, 493, 494, 495, 496, 497, 498, 499, 500, 501, 502, 503, 504, 505, 506, 507, 508, 509, 510, 511, 512, 513, 514, 515, 516, 517, 518, 519, 520, 521, 522, 523, 524, 525, 526, 527, 528, 529, 530, 531, 532, 533, 534, 535, 536, 537, 538, 539, 540, 541, 542, 543, 544, 545, 546, 547, 548, 549, 550, 551, 552, 553, 554, 555, 556, 557, 558, 559, 560, 561, 562, 563, 564, 565, 566, 567, 568, 569, 570, 571, 572, 600, 700, 800, 900, or 1000 methylation sites of Table 3. Analyses of each and every specific combination of the methylation sites of Table 3 are contemplated herein. In some embodiments, a subject is classified as having SCLC-N based on detection of differential methylation at at least or at most 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, or 46 methylation sites of Table 8. Analyses of each and every specific combination of the methylation sites of Table 8 are contemplated herein. In some embodiments, a subject is classified as having SCLC-A based on detection of differential methylation at at least or at most 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, or 30 methylation sites of Table 16. Analyses of each and every specific combination of the methylation sites of Table 16 are contemplated herein. In some embodiments, a subject is classified as having SCLC-N based on detection of differential methylation at at least or at most 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127, 128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 145, 146, 147, 148, 149, 150, 151, 152, 153, 154, 155, 156, 157, 158, 159, 160, 161, 162, 163, 164, 165, 166, 167, 168, 169, 170, 171, 172, 173, 174, 175, 176, 177, 178, 179, 180, 181, 182, 183, 184, 185, 186, 187, 188, 189, 190, 191, 192, 193, 194, 195, 196, 197, 198, 199, 200, 201, 202, 203, 204, 205, 206, 207, 208, 209, 210, 211, 212, 213, 214, 215, 216, 217, 218, 219, 220, 221, 222, 223, 224, 225, 226, 227, 228, 229, 230, 231, 232, 233, 234, 235, 236, 237, 238, 239, 240, 241, 242, 243, 244, 245, 246, 247, 248, 249, 250, 251, 252, 253, 254, 255, 256, 257, 258, 259, 260, 261, 262, 263, 264, 265, 266, 267, 268, 269, 270, 271, 272, 273, 274, 275, 276, 277, 278, 279, 280, 281, 282, 283, 284, 285, 286, 287, 288, 289, 290, 291, 292, 293, 294, 295, 296, 297, 298, 299, 300, 301, 302, 303, 304, 305, 306, 307, 308, 309, 310, 311, 312, 313, 314, 315, 316, 317, 318, 319, 320, 321, 322, 323, 324, 325, 326, 327, 328, 329, 330, 331, 332, 333, 334, 335, 336, 337, 338, 339, 340, 341, 342, 343, 344, 345, 346, 347, 348, 349, 350, 351, 352, 353, 354, 355, 356, 357, 358, 359, 360, 361, 362, 363, 364, 365, 366, 367, 368, 369, 370, 371, 372, 373, 374, 375, 376, 377, 378, 379, 380, 381, 382, 383, 384, 385, 386, 387, 388, 389, 390, 391, 392, 393, 394, 395, 396, 397, 398, 399, 400, 401, 402, 403, 404, 405, 406, 407, 408, 409, 410, 411, 412, 413, 414, 415, 416, 417, 418, 419, 420, 421, 422, 423, 424, 425, 426, 427, 428, 429, 430, 431, 432, 433, 434, 435, 436, 437, 438, 439, 440, 441, 442, 443, 444, 445, 446, 447, 448, 449, 450, 451, 452, 453, 454, 455, 456, 457, 458, 459, 460, 461, 462, 463, 464, 465, 466, 467, 468, 469, 470, 471, 472, 473, 474, 475, 476, 477, 478, 479, 480, 481, 482, 483, 484, 485, 486, 487, 488, 489, 490, 491, 492, 493, 494, 495, 496, 497, 498, 499, 500, 501, 502, 503, 504, 505, 506, 507, 508, 509, 510, 511, 512, 513, 514, 515, 516, 517, 518, 519, 520, 521, 522, 523, 524, 525, 526, 527, 528, 529, 530, 531, 532, 533, 534, 535, 536, 537, 538, 539, 540, 541, 542, 543, 544, 545, 546, 547, 548, 549, 550, 551, 552, 553, 554, 555, 556, 557, 558, 559, 560, 561, 562, 563, 564, 565, 566, 567, 568, 569, 570, 571, 572, 600, 650, or 695 methylation sites of Table 21. Analyses of each and every specific combination of the methylation sites of Table 21 are contemplated herein. In some embodiments, SCLC-N is identified based on detection of differential methylation at at least or at most 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127, 128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 145, 146, 147, 148, 149, 150, 151, 152, 153, 154, 155, 156, 157, 158, 159, 160, 161, 162, 163, 164, 165, 166, 167, 168, 169, 170, 171, 172, 173, 174, 175, 176, 177, 178, 179, 180, 181, 182, 183, 184, 185, 186, 187, 188, 189, 190, 191, 192, 193, 194, 195, 196, 197, 198, 199, 200, 201, 202, 203, 204, 205, 206, 207, 208, 209, 210, 211, 212, 213, 214, 215, 216, 217, 218, 219, 220, 221, 222, 223, 224, 225, 226, 227, 228, 229, 230, 231, 232, 233, 234, 235, 236, 237, 238, 239, 240, 241, 242, 243, 244, 245, 246, 247, 248, 249, 250, 251, 252, 253, 254, 255, 256, 257, 258, 259, 260, 261, 262, 263, 264, 265, 266, 267, 268, 269, 270, 271, 272, 273, 274, 275, 276, 277, 278, 279, 280, 281, 282, 283, 284, 285, 286, 287, 288, 289, 290, 291, 292, 293, 294, 295, 296, 297, 298, 299, 300, 301, 302, 303, 304, 305, 306, 307, 308, 309, 310, 311, 312, 313, 314, 315, 316, 317, 318, 319, 320, 321, 322, 323, 324, 325, 326, 327, 328, 329, 330, 331, 332, 333, 334, 335, 336, 337, 338, 339, 340, 341, 342, 343, 344, 345, 346, 347, 348, 349, 350, 351, 352, 353, 354, 355, 356, 357, 358, 359, 360, 361, 362, 363, 364, 365, 366, 367, 368, 369, 370, 371, 372, 373, 374, 375, 376, 377, 378, 379, 380, 381, 382, 383, 384, 385, 386, 387, 388, 389, 390, 391, 392, 393, 394, 395, 396, 397, 398, 399, 400, 401, 402, 403, 404, 405, 406, 407, 408, 409, 410, 411, 412, 413, 414, 415, 416, 417, 418, 419, 420, 421, 422, 423, 424, 425, 426, 427, 428, 429, 430, 431, 432, 433, 434, 435, 436, 437, 438, 439, 440, 441, 442, 443, 444, 445, 446, 447, 448, 449, 450, 451, 452, 453, 454, 455, 456, 457, 458, 459, 460, 461, 462, 463, 464, 465, 466, 467, 468, 469, 470, 471, 472, 473, 474, 475, 476, 477, 478, 479, 480, 481, 482, 483, 484, 485, 486, 487, 488, 489, 490, 491, 492, 493, 494, 495, 496, 497, 498, 499, 500 methylation sites of Table 28. It is specifically contemplated that any one or more of the methylation sites of Table 28 may be excluded in embodiments described herein. In some embodiments, SCLC-N is identified based on detection of differential methylation of cg20505457, cg04220881, cg14755690, cg19798702, cg03920522, cg12187160, cg02531277, cg18780243, cg19028997, cg02314596, cg16498113, cg19513004, cg17401435, cg25043538, cg00648184, cg10414350, cg09309024, cg06440275, cg01431993, cg11528849, cg16640855, cg00369376, cg02836529, cg20806345, cg22976218, cg13538006, cg11887270, cg23731742, cg02622825, cg00284708, cg05234415, cg24657047, cg23994112, cg08399017, cg14647703, cg13969327, cg05214130, cg08573199, cg09621610, cg13417891, cg02902261, cg00678971, cg02243624, cg13808641, cg15076368, and/or cg11964216. In some embodiments, SCLC-N is identified based on detection of differential methylation of chr1:54356529, chr1:109296245, chr1:109296247, chr1:220653171, chr1:220653195, chr11:35853956, chr11:64154503, chr11:64154571, chr11:64154574, chr12:108792675, chr17:72440313, chr17:72440361, chr2:223901322, chr20:19919227, chr3:52468694, chr5:160245925, chr6:44261803, chr8:42275934, chr9:131721310, chr9:131721341, chr9:131721355, chr9:131721389, chr2:216909627, chr20:19919173, chr9:131721356, chr22:50276667, chr17:72440360, chr6:37537738, chr1:220653165, chr1:220653180, chr8:140270696, chr12:108792684, chr19:3656274, chr1:54356527, chr19:47650943, chr7:149261799, chr2:216380208, chr17:72440372, chr9:131721340, chr9:131721342, chr2:216380274, chr11:67493309, chr2:65583301, chr5:160245988, chr3:52468622, chr17:74823299, chr1:160362850, chr12:31009628, chr14:64633473, chr18:59049918, chr20:63878908, chr5:16538225, chr6:19719869, chr6:34128215, chr6:34128233, chr1:109296235, chr3:52522225, chr8:134941130, chr7:149261769, chr19:3656352, chr2:85733778, chr4:850796, chr3:126013960, chr19:3655899, chr22:44049853, chr9:120242580, chr1:41657833, chr1:220653181, chr11:8239208, chr2:65583300, chr5:16538207, chr6:34128222, chr9:131721343, chr7:149261778, chr14:105178678, chr12:31009602, chr1:28869236, chr1:220653223, chr7:44254153, chr6:43475701, chr15:68347588, chr20:49345755, chr5:160245950, chr19:3656298, chr19:3655920, chr20:49345760, chr6:34128216, chr3:52468649, chr1:944700, chr1:54356503, chr1:54356526, chr1:54356528, chr2:216909691, chr5:160245949, chr21:41490949, chr17:50076230, chr2:25702014, chr19:3655770, chr9:120242557, chr16:85439239, chr1:53320062, chr5:16538206, chr6:19719865, chr11:855989, chr19:3655921, chr6:107633786, chr19:14182660, chr19:48350598, chr3:52468650, chr16:10622418, chr3:52468678, chr11:20055879, chr2:216909621, chr6:34128193, chr16:85287295, chr1:53320061, chr7:100890535, chr12:48675723, chr2:25701951, chr20:63835624, chr4:76612797, chr6:43475769, chr3:16132696, chr11:66866493, chr12:31009572, chr1:226588954, chr16:66960251, chr19:3656369, chr17:4809230, chr7:157018053, chr20:11271495, chr17:82001560, chr17:82001559, chr2:85770228, chr20:49345801, chr21:41458778, chr6:34128249, chr11:44963230, chr1:944730, chr12:108792716, chr22:44049787, chr3:52522201, chr4:6308154, chr2:85733793, chr19:12953781, chr1:43550353, chr21:41490965, chr12:108792685, chr3:16132702, chr1:15723882, chr1:54356555, chr12:130484433, chr17:4809161, chr6:19719861, chr6:26385134, chr6:168130602, chr19:13913675, chr16:85287080, chr11:888785, chr19:3655898, chr1:1921168, chr2:200087052, chr19:2354832, chr11:129699789, chr1:28869229, chr19:18422970, chr1:944737, chr22:44049781, chr20:25239829, chr9:120242569, chr6:148509695, chr1:153536157, chr9:120242617, chr12:31009603, chr18:62333487, chr8:140270737, chr19:3655888, chr17:82001529, chr7:102424329, chr2:200087071, chr16:85287095, chr11:855972, chr11:855981, chr9:120242622, chr19:3656250, chr20:19836028, chr1:944699, chr17:2418940, chr3:185397845, chr7:44151120, chr11:35853892, chr12:123253744, chr20:49345788, chr6:34128234, chr7:750747, chr2:205764439, chr18:59050139, chr5:172103442, chr9:120242544, chr1:28869207, chr16:11997774, chr8:134499858, chr17:29158240, chr1:54356559, chr6:34545466, chr8:134941060, chr10:101780858, chr19:12953855, chr3:53702770, chr12:56997304, chr6:34128223, chr18:77053845, chr20:22557408, chr6:110414306, chr9:136013178, chr1:230759612, chr6:44261814, chr6:42963345, chr9:95738191, chr16:85355101, chr19:2354863, chr1:53320016, chr16:70318894, chr16:85696894, chr17:82001584, chr2:200087032, chr7:128075308, chr1:32885121, chr21:41665312, chr7:128881062, chr6:169160984, chr3:196992182, chr6:40349319, chr7:44151126, chr1:54356214, chr7:5276684, chr19:38253104, chr1:204921255, chr1:224184849, chr11:48025532, chr5:16538197, chr1:153536113, chr1:153536123, chr9:124820965, chr21:41639350, chr9:113901422, chr1:11965505, chr6:168638645, chr17:29582881, chr3:71074388, chr9:134486435, chr19:48350605, chr19:3656178, chr11:118901571, chr1:43550383, chr12:123253763, chr16:30030208, chr21:41648785, chr9:91810447, chr10:79313956, chr6:169190341, chr16:85436880, chr1:1921165, chr1:205447760, chr1:153536136, chr1:153536146, chr11:19730746, chr3:141093639, chr2:159228539, chr21:17508899, chr11:66866541, chr17:66830069, chr20:49345770, chr20:63835571, chr9:127200650, chr19:4055918, chr9:131810494, chr19:38253123, chr1:60903781, chr22:20014786, chr1:25771857, chr17:67652635, chr9:93166951, chr13:73218843, chr7:136045406, chr14:73228468, chr17:50831246, chr7:30171980, chr17:67652633, chr1:28869065, chr13:113818528, chr2:200087031, chr2:200087051, chr6:168517547, chr6:35534674, chr6:35534714, chr6:148509713, chr19:3656386, chr11:19832444, chr13:112775959, chr22:19632813, chr5:760546, chr19:3950318, chr1:60903756, chr7:8070969, chr16:70730157, chr20:49345761, chr3:45819148, chr6:19719834, chr6:34128254, chr6:34128257, chr6:168130634, chr1:15723893, chr16:85287162, chr7:1815269, chr9:93166950, chr16:85287116, chr17:67652568, chr12:123253794, chr16:85287098, chr18:77077978, chr19:46714207, chr3:53702765, chr7:3998211, chr9:92729620, chr16:85436709, chr11:66866538, chr22:44248796, chr6:34545471, chr7:102424320, chr17:602149, chr20:22557482, chr6:3444679, chr17:57707866, chr16:11654442, chr19:3655812, chr13:109334658, chr1:43550373, chr2:73080399, chr9:131810462, chr1:227920141, chr1:153536121, chr20:50035301, chr20:38700627, chr21:41553133, chr21:41648778, chr6:168130595, chr6:168539582, chr7:5276649, chr21:40144935, chr19:3656261, chr3:139718818, chr1:10625828, chr3:185397835, chr7:110084403, chr5:176843791, chr6:40349351, chr9:113901566, chr21:41179996, chr4:528986, chr12:48675786, chr19:13634667, chr6:168130574, chr19:3656190, chr1:202168439, chr12:124428932, chr6:34545461, chr7:3998240, chr3:127304410, chr16:89847327, chr1:226638169, chr1:181128695, chr1:54356181, chr12:123253764, chr11:64056580, chr3:47236186, chr16:85436855, chr11:888597, chr19:4010290, chr1:53320091, chr1:205257276, chr19:4010298, chr21:41648770, chr7:122306890, chr20:11271554, chr4:7911302, chr1:28869195, chr16:2455154, chr5:176843804, chr7:5276677, chr1:220653196, chr11:888641, chr19:38253076, chr4:1858204, chr8:38495138, chr3:141093636, chr1:31627824, chr12:48675768, chr2:190034714, chr6:168638690, chr19:3656351, chr12:131864061, chr9:89591607, chr17:74823356, chr16:85287017, chr16:88887476, chr2:96174325, chr6:3444622, chr1:5917479, chr1:1240684, chr12:130483799, chr13:110123705, chr6:168496991, chr8:53733503, chr7:105689129, chr2:113974997, chr12:591924, chr15:65333873, chr3:194305584, chr19:4059381, chr18:59049874, chr1:224184822, chr11:76175216, chr6:168130594, chr19:3655954, chr19:34999970, chr6:26614205, chr10:78139388, chr11:122984321, chr19:3656172, chr1:43550344, chr12:129694731, chr19:3655828, chr7:151045548, chr12:130483815, chr5:78519838, chr11:888359, chr1:205032318, chr9:120242579, chr1:16486605, chr1:20348597, chr2:43203382, chr6:168130603, chr17:3695871, chr11:19714522, chr16:85439179, chr7:122306891, chr9:130233164, chr2:47020392, chr19:3655938, chr8:58989422, chr17:80001489, chr2:5530198, chr19:3656393, chr7:1815299, chr21:43860194, chr6:168355227, chr1:20348596, chr7:5478011, chr2:200087040, chr19:48371166, chr16:22288921, chr19:12953833, chr11:888360, chr5:16538196, chr1:9251757, chr11:924646, chr12:131864094, chr2:25701937, chr6:168538915, chr9:127636823, chr1:22809032, chr17:29065994, chr6:168517537, chr4:6308178, chr1:61198659, chr20:11271453, chr7:44151141, chr19:18745096, chr7:30172111, chr6:34433316, chr12:119869919, chr13:110123752, chr17:29582888, chr18:36468445, chr19:4010297, chr19:39307494, chr20:63835620, chr21:41375919, chr5:6859175, chr6:37537680, chr7:100122236, chr9:93959419, chr9:91810580, chr17:73726103, chr1:226589216, chr9:23452269, chr6:42963307, chr8:140321186, and/or chr16:85287074, including any combination thereof.


In some embodiments, a subject is classified as having SCLC-P. In some embodiments, a subject is classified as having SCLC-P based on detection of differential methylation at at least or at most 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127, 128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 145, 146, 147, 148, 149, 150, 151, 152, 153, 154, 155, 156, 157, 158, 159, 160, 161, 162, 163, 164, 165, 166, 167, 168, 169, 170, 171, 172, 173, 174, 175, 176, 177, 178, 179, 180, 181, 182, 183, 184, 185, 186, 187, 188, 189, 190, 191, 192, 193, 194, 195, 196, 197, 198, 199, 200, 201, 202, 203, 204, 205, 206, 207, 208, 209, 210, 211, 212, 213, 214, 215, 216, 217, 218, 219, 220, 221, 222, 223, 224, 225, 226, 227, 228, 229, 230, 231, 232, 233, 234, 235, 236, 237, 238, 239, 240, 241, 242, 243, 244, 245, 246, 247, 248, 249, 250, 251, 252, 253, 254, 255, 256, 257, 258, 259, 260, 261, 262, 263, 264, 265, 266, 267, 268, 269, 270, 271, 272, 273, 274, 275, 276, 277, 278, 279, 280, 281, 282, 283, 284, 285, 286, 287, 288, 289, 290, 291, 292, 293, 294, 295, 296, 297, 298, 299, 300, 301, 302, 303, 304, 305, 306, 307, 308, 309, 310, 311, 312, 313, 314, 315, 316, 317, 318, 319, 320, 321, 322, 323, 324, 325, 326, 327, 328, 329, 330, 331, 332, 333, 334, 335, 336, 337, 338, 339, 340, 341, 342, 343, 344, 345, 346, 347, 348, 349, 350, 351, 352, 353, 354, 355, 356, 357, 358, 359, 360, 361, 362, 363, 364, 365, 366, 367, 368, 369, 370, 371, 372, 373, 374, 375, 376, 377, 378, 379, 380, 381, 382, 383, 384, 385, 386, 387, 388, 389, 390, 391, 392, 393, 394, 395, 396, 397, 398, 399, 400, 401, 402, 403, 404, 405, 406, 407, 408, 409, 410, 411, 412, 413, 414, 415, 416, 417, 418, 419, 420, 421, 422, 423, 424, 425, 426, 427, 428, 429, 430, 431, 432, 433, 434, 435, 436, 437, 438, 439, 440, 441, 442, 443, 444, 445, 446, 447, 448, 449, 450, 451, 452, 453, 454, 455, 456, 457, 458, 459, 460, 461, 462, 463, 464, 465, 466, 467, 468, 469, 470, 471, 472, 473, 474, 475, 476, 477, 478, 479, 480, 481, 482, 483, 484, 485, 486, 487, 488, 489, 490, 491, 492, 493, 494, 495, 496, 497, 498, 499, 500, 501, 502, 503, 504, 505, 506, 507, 508, 509, 510, 511, 512, 513, 514, 515, 516, 517, 518, 519, 520, 521, 522, 523, 524, 525, 526, 527, 528, 529, 530, 531, 532, 533, 534, 535, 536, 537, 538, 539, 540, 541, 542, 543, 544, 545, 546, 547, 548, 549, 550, 551, 552, 553, 554, 555, 556, 557, 558, 559, 560, 561, 562, 563, 564, 565, 566, 567, 568, 569, 570, 571, 572, 600, 700, 800, 900, or 1000 methylation sites of Table 4. Analyses of each and every specific combination of the methylation sites of Table 4 are contemplated herein. In some embodiments, a subject is classified as having SCLC-P based on detection of differential methylation at at least or at most 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, or 93 methylation sites of Table 9. Analyses of each and every specific combination of the methylation sites of Table 9 are contemplated herein. In some embodiments, a subject is classified as having SCLC-A based on detection of differential methylation at at least or at most 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, or 30 methylation sites of Table 17. Analyses of each and every specific combination of the methylation sites of Table 17 are contemplated herein. In some embodiments, a subject is classified as having SCLC-P based on detection of differential methylation at at least or at most 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127, 128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 145, 146, 147, 148, 149, 150, 151, 152, 153, 154, 155, 156, 157, 158, 159, 160, 161, 162, 163, 164, 165, 166, 167, 168, 169, 170, 171, 172, 173, 174, 175, 176, 177, 178, 179, 180, 181, 182, 183, 184, 185, 186, 187, 188, 189, 190, 191, 192, 193, 194, 195, 196, 197, 198, 199, 200, 201, 202, 203, 204, 205, 206, 207, 208, 209, 210, 211, 212, 213, 214, 215, 216, 217, 218, 219, 220, 221, 222, 223, 224, 225, 226, 227, 228, 229, 230, 231, 232, 233, 234, 235, 236, 237, 238, 239, 240, 241, 242, 243, 244, 245, 246, 247, 248, 249, 250, 251, 252, 253, 254, 255, 256, 257, 258, 259, 260, 261, 262, 263, 264, 265, 266, 267, 268, 269, 270, 271, 272, 273, 274, 275, 276, 277, 278, 279, 280, 281, 282, 283, 284, 285, 286, 287, 288, 289, 290, 291, 292, 293, 294, 295, 296, 297, 298, 299, 300, 301, 302, 303, 304, 305, 306, 307, 308, 309, 310, 311, 312, 313, 314, 315, 316, 317, 318, 319, 320, 321, 322, 323, 324, 325, 326, 327, 328, 329, 330, 331, 332, 333, 334, 335, 336, 337, 338, 339, 340, 341, 342, 343, 344, 345, 346, 347, 348, 349, 350, 351, 352, 353, 354, 355, 356, 357, 358, 359, 360, 361, 362, 363, 364, 365, 366, 367, 368, 369, 370, 371, 372, 373, 374, 375, 376, 377, 378, 379, 380, 381, 382, 383, 384, 385, 386, 387, 388, 389, 390, 391, 392, 393, 394, 395, 396, 397, 398, 399, 400, 401, 402, 403, 404, 405, 406, 407, 408, 409, 410, 411, 412, 413, 414, 415, 416, 417, 418, 419, 420, 421, 422, 423, 424, 425, 426, 427, 428, 429, 430, 431, 432, 433, 434, 435, 436, 437, 438, 439, 440, 441, 442, 443, 444, 445, 446, 447, 448, 449, 450, 451, 452, 453, 454, 455, 456, 457, 458, 459, 460, 461, 462, 463, 464, 465, 466, 467, 468, 469, 470, 471, 472, 473, 474, 475, 476, 477, 478, 479, 480, 481, 482, 483, 484, 485, 486, 487, 488, 489, 490, 491, 492, 493, 494, 495, 496, 497, 498, 499, 500, 501, 502, 503, 504, 505, 506, 507, 508, 509, 510, 511, 512, 513, 514, 515, 516, 517, 518, 519, 520, 521, 522, 523, 524, 525, 526, 527, 528, 529, 530, 531, 532, 533, 534, 535, 536, 537, 538, 539, 540, 541, 542, 543, 544, 545, 546, 547, 548, 549, 550, 551, 552, 553, 554, 555, 556, 557, 558, 559, 560, 561, 562, 563, 564, 565, 566, 567, 568, 569, 570, 571, 572, 600, 700, 800, 900, or 989 methylation sites of Table 22. Analyses of each and every specific combination of the methylation sites of Table 22 are contemplated herein. In some embodiments, SCLC-P is identified based on detection of differential methylation at at least or at most 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127, 128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 145, 146, 147, 148, 149, 150, 151, 152, 153, 154, 155, 156, 157, 158, 159, 160, 161, 162, 163, 164, 165, 166, 167, 168, 169, 170, 171, 172, 173, 174, 175, 176, 177, 178, 179, 180, 181, 182, 183, 184, 185, 186, 187, 188, 189, 190, 191, 192, 193, 194, 195, 196, 197, 198, 199, 200, 201, 202, 203, 204, 205, 206, 207, 208, 209, 210, 211, 212, 213, 214, 215, 216, 217, 218, 219, 220, 221, 222, 223, 224, 225, 226, 227, 228, 229, 230, 231, 232, 233, 234, 235, 236, 237, 238, 239, 240, 241, 242, 243, 244, 245, 246, 247, 248, 249, 250, 251, 252, 253, 254, 255, 256, 257, 258, 259, 260, 261, 262, 263, 264, 265, 266, 267, 268, 269, 270, 271, 272, 273, 274, 275, 276, 277, 278, 279, 280, 281, 282, 283, 284, 285, 286, 287, 288, 289, 290, 291, 292, 293, 294, 295, 296, 297, 298, 299, 300, 301, 302, 303, 304, 305, 306, 307, 308, 309, 310, 311, 312, 313, 314, 315, 316, 317, 318, 319, 320, 321, 322, 323, 324, 325, 326, 327, 328, 329, 330, 331, 332, 333, 334, 335, 336, 337, 338, 339, 340, 341, 342, 343, 344, 345, 346, 347, 348, 349, 350, 351, 352, 353, 354, 355, 356, 357, 358, 359, 360, 361, 362, 363, 364, 365, 366, 367, 368, 369, 370, 371, 372, 373, 374, 375, 376, 377, 378, 379, 380, 381, 382, 383, 384, 385, 386, 387, 388, 389, 390, 391, 392, 393, 394, 395, 396, 397, 398, 399, 400, 401, 402, 403, 404, 405, 406, 407, 408, 409, 410, 411, 412, 413, 414, 415, 416, 417, 418, 419, 420, 421, 422, 423, 424, 425, 426, 427, 428, 429, 430, 431, 432, 433, 434, 435, 436, 437, 438, 439, 440, 441, 442, 443, 444, 445, 446, 447, 448, 449, 450, 451, 452, 453, 454, 455, 456, 457, 458, 459, 460, 461, 462, 463, 464, 465, 466, 467, 468, 469, 470, 471, 472, 473, 474, 475, 476, 477, 478, 479, 480, 481, 482, 483, 484, 485, 486, 487, 488, 489, 490, 491, 492, 493, 494, 495, 496, 497, 498, 499, 500 methylation sites of Table 29. Analyses of each and every specific combination of the methylation sites of Table 29 are contemplated herein. It is specifically contemplated that any one or more of the methylation sites of Table 29 may be excluded in embodiments described herein. In some embodiments, SCLC-P is identified based on detection of differential methylation of cg27232389, cg03020852, cg11691710, cg14197123, cg17885507, cg03517570, cg13297671, cg18795320, cg03075214, cg06832246, cg05683632, cg00704369, cg22171098, cg09934399, cg02817764, cg24677222, cg16770048, cg14701925, cg04182076, cg18969798, cg03803789, cg13240089, cg17758792, cg06923861, cg07956003, cg08275278, cg04983681, cg17728697, cg09472222, cg02220284, cg05366160, cg13705753, cg06839854, cg02675973, cg05395645, cg25601286, cg11701604, cg07825782, cg00600617, cg16054907, cg01489441, cg15564226, cg10026427, cg01149239, cg04479757, cg11019743, cg13207778, cg25296465, cg03387092, cg14175330, cg05999426, cg19011089, cg14313328, cg18529415, cg04563108, cg25874150, cg16318349, cg13081156, cg14088354, cg03264729, cg01580044, cg07313835, cg11597418, cg26855672, cg03356778, cg05216984, cg02593168, cg20314331, cg26797073, cg15873449, cg18983310, cg08265811, cg22340762, cg00618183, cg12452539, cg15786168, cg06669752, cg24136932, cg24272324, cg04619304, cg01772824, cg13921012, cg06542565, cg10288437, cg10609655, cg07262682, cg21289124, cg07325342, cg14211075, cg00719067, cg05554594, cg08368885, and/or cg21876001. In some embodiments, SCLC-P is identified based on detection of differential methylation of chr1:11032833, chr1:15207848, chr1:15945017, chr1:17026179, chr1:25741499, chr1:27551002, chr1:32327585, chr1:42682988, chr1:52365896, chr1:56552275, chr1:116407596, chr1:147829076, chr1:156538486, chr1:156750879, chr1:164576909, chr1:197915932, chr1:204289083, chr1:204571233, chr1:212618744, chr1:212618752, chr1:212638013, chr1:231162869, chr1:231162872, chr1:231162880, chr10:14365352, chr10:55631088, chr10:55631097, chr10:97713353, chr10:97713362, chr10:123017613, chr11:63997490, chr11:65536690, chr11:75410397, chr11:77750252, chr11:126313324, chr12:433809, chr12:7291128, chr12:57128650, chr12:67389978, chr12:75861004, chr12:81759542, chr12:85489437, chr12:101309330, chr12:103993054, chr12:104599362, chr12:104599370, chr12:105977083, chr12:110245057, chr12:110245058, chr12:110245093, chr12:111841988, chr12:120456258, chr12:122032753, chr12:122032775, chr12:124497504, chr12:124524949, chr12:124631301, chr13:20345144, chr14:89701670, chr14:105392906, chr14:105392911, chr15:43746172, chr15:58701617, chr15:74789232, chr15:74789276, chr15:74789281, chr16:234790, chr16:234826, chr16:648840, chr16:1498961, chr16:1746192, chr16:2075993, chr16:2964040, chr16:4767447, chr16:8621572, chr16:28193303, chr16:28863649, chr16:29906931, chr16:30125736, chr16:30973692, chr16:66696829, chr16:68341637, chr16:85611879, chr17:21665928, chr17:29576080, chr17:34252590, chr17:43187274, chr17:48932449, chr17:49816143, chr17:63383824, chr17:63383830, chr17:63739476, chr17:64661931, chr17:68205724, chr17:72165644, chr17:76420086, chr17:77439476, chr17:77439513, chr17:81248481, chr17:81248517, chr18:5543758, chr18:5543760, chr18:5543767, chr18:5543774, chr18:14907472, chr18:28175723, chr18:28175730, chr18:28175734, chr18:28175743, chr18:57574427, chr19:807444, chr19:811705, chr19:991153, chr19:991161, chr19:1633524, chr19:1993008, chr19:2115209, chr19:5618219, chr19:11483864, chr19:11483872, chr19:11483877, chr19:11483882, chr19:11483887, chr19:11483902, chr19:11483907, chr19:11483912, chr19:14206288, chr19:14559510, chr19:16628375, chr19:17209718, chr19:17209725, chr19:17209733, chr19:17209752, chr19:18778224, chr19:35721194, chr19:35944911, chr19:38907710, chr19:42211188, chr19:45712682, chr19:49464557, chr19:49881697, chr19:55284281, chr19:55615832, chr2:9003857, chr2:61166980, chr2:89848744, chr2:190440760, chr2:200981406, chr2:202250239, chr2:209772183, chr2:224690031, chr20:1185694, chr20:62122215, chr20:62309811, chr20:62328882, chr20:63667368, chr21:5137123, chr21:25735328, chr21:41879374, chr21:43882191, chr21:45277832, chr22:31098838, chr22:33058579, chr22:40026246, chr22:49884754, chr3:13366052, chr3:112523580, chr3:112523614, chr3:128428346, chr3:138798882, chr3:150408978, chr3:157067444, chr3:165348114, chr3:165348116, chr3:186783828, chr3:197297920, chr4:1229607, chr4:4438102, chr5:3750940, chr5:6615113, chr5:16179849, chr5:16179857, chr5:16179865, chr5:16179878, chr5:16179881, chr5:16179883, chr5:16180008, chr5:178204129, chr5:178204131, chr6:3577167, chr6:27279630, chr6:73310426, chr6:73310429, chr6:73310454, chr6:73310463, chr6:125791186, chr6:136290429, chr7:996193, chr7:1551166, chr7:1849861, chr7:1854236, chr7:4730195, chr7:5070131, chr7:6333296, chr7:15848453, chr7:26247657, chr7:29643153, chr7:30043812, chr7:43877706, chr7:44146254, chr7:44748739, chr7:149022546, chr8:31640044, chr8:31640053, chr8:31640067, chr8:42842942, chr8:80578027, chr9:107245787, chr9:120913537, chr9:126408197, chr9:131584010, chr9:136197462, chr9:136451036, chr9:136451222, chr9:136451519, chr9:137013461, chr9:137013470, chr9:137013473, chr9:137013486, chr9:137278360, chr9:137278384, chr9:137278402, chr9:137278488, chrX:150899022, chr6:34553001, chr12:118980854, chr19:811773, chr2:130345606, chr2:202250236, chr7:1005784, chr19:7934275, chr14:34024477, chr7:107390004, chr1:25216043, chr15:85610808, chr19:5668214, chr7:5297184, chr1:241356405, chr10:102714534, chr8:31640064, chr12:120967099, chr19:1393965, chr15:25438570, chr15:74789270, chr7:5297124, chr8:123443315, chr1:180269892, chr19:1456332, chr16:73028748, chr2:75056446, chr19:18543346, chr2:75056435, chr2:75056445, chr16:29876586, chr6:43771035, chr12:124344199, chr8:139649190, chr2:230068915, chr1:6461087, chr1:234661304, chr12:7824990, chr16:71931876, chr21:36736273, chr3:183636771, chr5:143405413, chr10:69402478, chr14:104887313, chr16:1315523, chr7:2295681, chr1:214108494, chr1:236064214, chr2:44168465, chr2:114662163, chr3:107999730, chr6:3577155, chr6:3577177, chr7:57818168, chr1:41324219, chr1:213051051, chr11:4521815, chr12:43552603, chr17:35488134, chr3:14401986, chr6:13450944, chr9:101738883, chr1:167221470, chr16:88880826, chr19:3652127, chr20:17396399, chr12:104599364, chr16:87827109, chr19:17873403, chr19:17873409, chr19:17873411, chr6:63656136, chr12:45216305, chr12:57837371, chr16:21557088, chr17:34331252, chr21:39054428, chr7:3910633, chr16:3655081, chr18:12324746, chr9:76701152, chr19:1648427, chr20:47468584, chr3:96841981, chr1:239386481, chr19:3088153, chr20:17396185, chr6:27557116, chr6:55680614, chr7:5297111, chr19:58440360, chr7:151111578, chr8:139649329, chr19:28520192, chr6:34778112, chr9:131112163, chr7:102201787, chr8:42153025, chr8:42622755, chr1:154174789, chr17:49816136, chr19:7934266, chr19:13207507, chr2:17317571, chr5:3754702, chr6:24626028, chr6:44653805, chr2:173307231, chr6:22509101, chr8:107889762, chr5:128879466, chr19:3094373, chr17:72235698, chr21:34510358, chr9:137013468, chr9:137013480, chr1:220001751, chr5:308909, chr1:155544582, chr1:204089544, chr11:107970310, chr12:95066688, chr19:16553992, chr5:16179995, chr5:16180003, chr5:25900907, chr8:35235230, chr16:28617820, chr17:76419894, chr19:48194427, chr7:14695759, chr1:6470978, chr1:23636028, chr20:350196, chr1:31193833, chr8:126862783, chr11:78046094, chr12:132528585, chr18:79375872, chr19:652099, chr21:9873175, chr7:57821358, chr7:101967581, chr8:144107705, chr12:62602516, chr1:6460819, chr1:244198034, chr19:5704451, chr9:137278356, chr10:76887333, chr19:1433766, chr19:13830675, chr20:37985816, chr1:15945048, chr14:23078131, chr9:133459357, chr8:31640070, chr12:62799867, chr5:32446706, chr12:120967103, chr5:128879583, chr15:69087040, chr20:347269, chr9:132325224, chr16:78195948, chr19:28824412, chr19:44753544, chr22:11288465, chr17:72123931, chr17:72124220, chr17:72124238, chr2:36973823, chr5:16179886, chr20:44560834, chr12:50057840, chr19:1456317, chr7:1421100, chr8:123443370, chr17:82626176, chr18:63283742, chr11:65650576, chr12:31591065, chr16:73028716, chr6:106135145, chr1:230399219, chr17:80599748, chr3:136614019, chr9:93826472, chr19:812407, chr6:135771171, chr9:137278500, chr16:3987194, chr17:49810078, chr2:164717792, chr22:40600900, chr3:123976907, chr3:123976934, chr2:89244905, chr19:5668194, chr11:78046073, chr9:127507984, chr9:120877473, chr1:159210159, chr6:44441882, chr8:101950035, chr1:11331701, chr19:1992998, chr19:1993003, chr9:128704978, chr9:124453638, chr19:1468243, chr16:2429260, chr20:62309824, chr7:44146237, chr8:31640050, chr9:94914976, chr12:37419025, chr12:45776142, chr17:42670166, chr19:1633551, chr9:137281710, chr1:214281447, chr6:34553086, chr1:167918494, chr17:72123590, chr19:45067160, chr6:157300486, chr7:1734991, chr7:1734996, chr1:70338695, chr19:18868002, chr9:14041343, chr10:76887324, chr19:7934351, chr19:13644740, chr2:5691280, chr5:134550960, chr12:95633568, chr1:6460956, chr16:17134583, chr16:17134595, chr16:61149835, chr19:4101376, chr19:37692212, chr6:1494847, chr7:38178231, chr7:71132295, chr11:134072686, chr16:2720277, chr16:11345580, chr17:29613358, chr18:14867181, chr19:3613344, chr2:209772188, chr6:34552991, chr6:88962788, chr12:105977085, chr17:7479367, chr17:21379559, chr19:10502839, chr19:39178093, chr21:43313606, chr22:31306646, chr3:11717633, chr3:139539693, chr7:4730228, chr4:154375969.


In some embodiments, a subject is classified as having SCLC-I. In some embodiments, a subject is classified as having SCLC-I based on detection of differential methylation at at least or at most 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127, 128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 145, 146, 147, 148, 149, 150, 151, 152, 153, 154, 155, 156, 157, 158, 159, 160, 161, 162, 163, 164, 165, 166, 167, 168, 169, 170, 171, 172, 173, 174, 175, 176, 177, 178, 179, 180, 181, 182, 183, 184, 185, 186, 187, 188, 189, 190, 191, 192, 193, 194, 195, 196, 197, 198, 199, 200, 201, 202, 203, 204, 205, 206, 207, 208, 209, 210, 211, 212, 213, 214, 215, 216, 217, 218, 219, 220, 221, 222, 223, 224, 225, 226, 227, 228, 229, 230, 231, 232, 233, 234, 235, 236, 237, 238, 239, 240, 241, 242, 243, 244, 245, 246, 247, 248, 249, 250, 251, 252, 253, 254, 255, 256, 257, 258, 259, 260, 261, 262, 263, 264, 265, 266, 267, 268, 269, 270, 271, 272, 273, 274, 275, 276, 277, 278, 279, 280, 281, 282, 283, 284, 285, 286, 287, 288, 289, 290, 291, 292, 293, 294, 295, 296, 297, 298, 299, 300, 301, 302, 303, 304, 305, 306, 307, 308, 309, 310, 311, 312, 313, 314, 315, 316, 317, 318, 319, 320, 321, 322, 323, 324, 325, 326, 327, 328, 329, 330, 331, 332, 333, 334, 335, 336, 337, 338, 339, 340, 341, 342, 343, 344, 345, 346, 347, 348, 349, 350, 351, 352, 353, 354, 355, 356, 357, 358, 359, 360, 361, 362, 363, 364, 365, 366, 367, 368, 369, 370, 371, 372, 373, 374, 375, 376, 377, 378, 379, 380, 381, 382, 383, 384, 385, 386, 387, 388, 389, 390, 391, 392, 393, 394, 395, 396, 397, 398, 399, 400, 401, 402, 403, 404, 405, 406, 407, 408, 409, 410, 411, 412, 413, 414, 415, 416, 417, 418, 419, 420, 421, 422, 423, 424, 425, 426, 427, 428, 429, 430, 431, 432, 433, 434, 435, 436, 437, 438, 439, 440, 441, 442, 443, 444, 445, 446, 447, 448, 449, 450, 451, 452, 453, 454, 455, 456, 457, 458, 459, 460, 461, 462, 463, 464, 465, 466, 467, 468, 469, 470, 471, 472, 473, 474, 475, 476, 477, 478, 479, 480, 481, 482, 483, 484, 485, 486, 487, 488, 489, 490, 491, 492, 493, 494, 495, 496, 497, 498, 499, 500, 501, 502, 503, 504, 505, 506, 507, 508, 509, 510, 511, 512, 513, 514, 515, 516, 517, 518, 519, 520, 521, 522, 523, 524, 525, 526, 527, 528, 529, 530, 531, 532, 533, 534, 535, 536, 537, 538, 539, 540, 541, 542, 543, 544, 545, 546, 547, 548, 549, 550, 551, 552, 553, 554, 555, 556, 557, 558, 559, 560, 561, 562, 563, 564, 565, 566, 567, 568, 569, 570, 571, 572, 600, 700, 800, 900, or 1000 methylation sites of Table 5. Analyses of each and every specific combination of the methylation sites of Table 5 are contemplated herein. In some embodiments, a subject is classified as having SCLC-I based on detection of differential methylation at at least or at most 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, or 44 methylation sites of Table 10. Analyses of each and every specific combination of the methylation sites of Table 10 are contemplated herein. In some embodiments, a subject is classified as having SCLC-A based on detection of differential methylation at at least or at most 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, or 30 methylation sites of Table 18. Analyses of each and every specific combination of the methylation sites of Table 18 are contemplated herein. In some embodiments, a subject is classified as having SCLC-I based on detection of differential methylation at at least or at most 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127, 128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 145, 146, 147, 148, 149, 150, 151, 152, 153, 154, 155, 156, 157, 158, 159, 160, 161, 162, 163, 164, 165, 166, 167, 168, 169, 170, 171, 172, 173, 174, 175, 176, 177, 178, 179, 180, 181, 182, 183, 184, 185, 186, 187, 188, 189, 190, 191, 192, 193, 194, 195, 196, 197, 198, 199, 200, 201, 202, 203, 204, 205, 206, 207, 208, 209, 210, 211, 212, 213, 214, 215, 216, 217, 218, 219, 220, 221, 222, 223, 224, 225, 226, 227, 228, 229, 230, 231, 232, 233, 234, 235, 236, 237, 238, 239, 240, 241, 242, 243, 244, 245, 246, 247, 248, 249, 250, 251, 252, 253, 254, 255, 256, 257, 258, 259, 260, 261, 262, 263, 264, 265, 266, 267, 268, 269, 270, 271, 272, 273, 274, 275, 276, 277, 278, 279, 280, 281, 282, 283, 284, 285, 286, 287, 288, 289, 290, 291, 292, 293, 294, 295, 296, 297, 298, 299, 300, 301, 302, 303, 304, 305, 306, 307, 308, 309, 310, 311, 312, 313, 314, 315, 316, 317, 318, 319, 320, 321, 322, 323, 324, 325, 326, 327, 328, 329, 330, 331, 332, 333, 334, 335, 336, 337, 338, 339, 340, 341, 342, 343, 344, 345, 346, 347, 348, 349, 350, 351, 352, 353, 354, 355, 356, 357, 358, 359, 360, 361, 362, 363, 364, 365, 366, 367, 368, 369, 370, 371, 372, 373, 374, 375, 376, 377, 378, 379, 380, 381, 382, 383, 384, 385, 386, 387, 388, 389, 390, 391, 392, 393, 394, 395, 396, 397, 398, 399, 400, 401, 402, 403, 404, 405, 406, 407, 408, 409, 410, 411, 412, 413, 414, 415, 416, 417, 418, 419, 420, 421, 422, 423, 424, 425, 426, 427, 428, 429, 430, 431, 432, 433, 434, 435, 436, 437, 438, 439, 440, 441, 442, 443, 444, 445, 446, 447, 448, 449, 450, 451, 452, 453, 454, 455, 456, 457, 458, 459, 460, 461, 462, 463, 464, 465, 466, 467, 468, 469, 470, 471, 472, 473, 474, 475, 476, 477, 478, 479, 480, 481, 482, 483, 484, 485, 486, 487, 488, 489, 490, 491, 492, 493, 494, 495, 496, 497, 498, 499, 500, 501, 502, 503, 504, 505, 506, 507, 508, 509, 510, 511, 512, 513, 514, 515, 516, 517, 518, 519, 520, 521, 522, 523, 524, 525, 526, 527, 528, 529, 530, 531, 532, 533, 534, 535, 536, 537, 538, 539, 540, 541, 542, 543, 544, 545, 546, 547, 548, 549, 550, 551, 552, 553, 554, 555, 556, 557, 558, 559, 560, 561, 562, 563, 564, 565, 566, 567, 568, 569, 570, 571, 572, 600, 700, 800, or 848 methylation sites of Table 23. Analyses of each and every specific combination of the methylation sites of Table 23 are contemplated herein. In some embodiments, SCLC-I is identified based on detection of differential methylation at at least or at most 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127, 128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 145, 146, 147, 148, 149, 150, 151, 152, 153, 154, 155, 156, 157, 158, 159, 160, 161, 162, 163, 164, 165, 166, 167, 168, 169, 170, 171, 172, 173, 174, 175, 176, 177, 178, 179, 180, 181, 182, 183, 184, 185, 186, 187, 188, 189, 190, 191, 192, 193, 194, 195, 196, 197, 198, 199, 200, 201, 202, 203, 204, 205, 206, 207, 208, 209, 210, 211, 212, 213, 214, 215, 216, 217, 218, 219, 220, 221, 222, 223, 224, 225, 226, 227, 228, 229, 230, 231, 232, 233, 234, 235, 236, 237, 238, 239, 240, 241, 242, 243, 244, 245, 246, 247, 248, 249, 250, 251, 252, 253, 254, 255, 256, 257, 258, 259, 260, 261, 262, 263, 264, 265, 266, 267, 268, 269, 270, 271, 272, 273, 274, 275, 276, 277, 278, 279, 280, 281, 282, 283, 284, 285, 286, 287, 288, 289, 290, 291, 292, 293, 294, 295, 296, 297, 298, 299, 300, 301, 302, 303, 304, 305, 306, 307, 308, 309, 310, 311, 312, 313, 314, 315, 316, 317, 318, 319, 320, 321, 322, 323, 324, 325, 326, 327, 328, 329, 330, 331, 332, 333, 334, 335, 336, 337, 338, 339, 340, 341, 342, 343, 344, 345, 346, 347, 348, 349, 350, 351, 352, 353, 354, 355, 356, 357, 358, 359, 360, 361, 362, 363, 364, 365, 366, 367, 368, 369, 370, 371, 372, 373, 374, 375, 376, 377, 378, 379, 380, 381, 382, 383, 384, 385, 386, 387, 388, 389, 390, 391, 392, 393, 394, 395, 396, 397, 398, 399, 400, 401, 402, 403, 404, 405, 406, 407, 408, 409, 410, 411, 412, 413, 414, 415, 416, 417, 418, 419, 420, 421, 422, 423, 424, 425, 426, 427, 428, 429, 430, 431, 432, 433, 434, 435, 436, 437, 438, 439, 440, 441, 442, 443, 444, 445, 446, 447, 448, 449, 450, 451, 452, 453, 454, 455, 456, 457, 458, 459, 460, 461, 462, 463, 464, 465, 466, 467, 468, 469, 470, 471, 472, 473, 474, 475, 476, 477, 478, 479, 480, 481, 482, 483, 484, 485, 486, 487, 488, 489, 490, 491, 492, 493, 494, 495, 496, 497, 498, 499, 500 methylation sites of Table 30. Analyses of each and every specific combination of the methylation sites of Table 30 are contemplated herein. It is specifically contemplated that any one or more of the methylation sites of Table 30 may be excluded in embodiments described herein. In some embodiments, SCLC-I is identified based on detection of differential methylation of cg09248054, cg02379560, cg04917391, cg05020685, cg06485940, cg16364495, cg05857126, cg13780782, cg02008691, cg24664798, cg17265693, cg06508056, cg15932065, cg16405211, cg18804920, cg23889772, cg07270851, cg24238564, cg03850035, cg02659920, cg05651265, cg10976861, cg24127874, cg02365303, cg11799006, cg00336977, cg02125259, cg09433131, cg14865862, cg20136513, cg00378510, cg06473097, cg23844705, cg19741167, cg16769791, cg00448761, cg04303901, cg13077545, cg15559684, cg07035875, cg19115272, cg06093379, cg19154027, and/or cg22073838. In some embodiments, SCLC-I is identified based on detection of differential methylation of chr1:1040462, chr1:1040475, chr1:1682754, chr1:6249894, chr1:6249902, chr1:6249914, chr1:6249917, chr1:12191832, chr1:15741578, chr1:16980570, chr1:16980579, chr1:16980593, chr1:18630506, chr1:20487144, chr1:21574155, chr1:23801501, chr1:24730777, chr1:24730787, chr1:24730788, chr1:24730796, chr1:24730797, chr1:25195867, chr1:31065986, chr1:36323440, chr1:39491967, chr1:43285575, chr1:43285577, chr1:43369421, chr1:89843439, chr1:89843473, chr1:145960916, chr1:153532886, chr1:153532890, chr1:156908050, chr1:163404039, chr1:163423088, chr1:163423133, chr1:163423188, chr1:163423194, chr1:163423199, chr1:163546298, chr1:164136579, chr1:164136587, chr1:164136632, chr1:164236230, chr1:164236242, chr1:165235591, chr1:167796909, chr1:208601823, chr1:213771516, chr1:213820223, chr1:213861854, chr1:213861907, chr1:213910457, chr1:225962005, chr1:230322908, chr1:240992226, chr1:241128149, chr1:243916475, chr10:99431109, chr10:132518774, chr11:366066, chr11:438565, chr11:438607, chr11:726201, chr11:848890, chr11:848923, chr11:848927, chr11:848933, chr11:849115, chr11:849137, chr11:849141, chr11:849142, chr11:849148, chr11:849149, chr11:17734970, chr11:44566012, chr11:45922046, chr11:45922074, chr11:45922076, chr11:45922090, chr11:45922100, chr11:45922275, chr11:45922276, chr11:45923059, chr11:45923077, chr11:46381467, chr11:64299743, chr11:64299761, chr11:64300844, chr11:64300851, chr11:64300858, chr11:64300884, chr11:64490631, chr11:64490632, chr11:64712787, chr11:65355635, chr11:65355646, chr11:65355670, chr11:65551424, chr11:65551425, chr11:67023317, chr11:67464932, chr11:67464964, chr11:73264689, chr11:75240135, chr11:85811258, chr11:89593934, chr11:92709117, chr11:93542959, chr11:114059499, chr11:114059530, chr11:114059757, chr11:114061199, chr11:114061210, chr11:114061212, chr11:114061215, chr11:114061239, chr11:114631735, chr11:115504986, chr11:115504997, chr11:115505001, chr11:117432347, chr11:117795858, chr11:118956922, chr11:119182275, chr11:119206066, chr11:119729116, chr11:120284546, chr11:124746873, chr11:124746909, chr11:124746913, chr11:124863373, chr11:124863394, chr11:125263544, chr11:129316134, chr11:130070945, chr11:130159700, chr11:130159829, chr11:130159851, chr11:130159854, chr11:133064200, chr11:133064212, chr11:133064221, chr11:133064231, chr11:133064233, chr11:134311382, chr12:6961918, chr12:6962633, chr12:6962646, chr12:6962648, chr12:6964182, chr12:16504002, chr12:16714352, chr12:16714353, chr12:25939377, chr12:32470696, chr12:32646853, chr12:42238116, chr12:49346692, chr12:51392037, chr12:52903995, chr12:52904021, chr12:52948914, chr12:96738497, chr12:96738507, chr12:97138576, chr12:97324958, chr12:97325039, chr12:97607417, chr12:97619683, chr12:97755215, chr12:97855295, chr12:97924591, chr12:98350733, chr12:103100480, chr12:103165897, chr12:103165901, chr12:103165909, chr12:103165933, chr12:108310791, chr12:108310792, chr12:108310807, chr12:109291976, chr12:109292004, chr12:119258242, chr12:119258280, chr12:132134549, chr12:132134577, chr12:132134595, chr12:132134596, chr12:132134600, chr12:132134601, chr12:132134630, chr13:21298314, chr13:34918433, chr13:35920681, chr13:38494047, chr13:38545892, chr13:39205350, chr13:39300854, chr13:42040772, chr13:54129564, chr13:54844155, chr13:55129970, chr13:55166399, chr13:59341409, chr13:70033781, chr13:73632816, chr13:73632851, chr13:78840351, chr13:101796812, chr13:101927978, chr13:101933364, chr13:102060417, chr13:102060419, chr13:102060451, chr13:102068532, chr13:102068551, chr13:102068563, chr13:102068572, chr13:102390033, chr13:110473172, chr13:110536576, chr13:110825816, chr13:110830973, chr13:112988667, chr13:113016746, chr13:113433650, chr14:21069139, chr14:21069177, chr14:21069183, chr14:22883379, chr14:26553939, chr14:29450905, chr14:29450950, chr14:29523990, chr14:30391455, chr14:37657127, chr14:37751915, chr14:37751924, chr14:37751973, chr14:37751985, chr14:37772760, chr14:37772778, chr14:37772795, chr14:37802591, chr14:38033650, chr14:38033658, chr14:38115498, chr14:38115499, chr14:38115532, chr14:38129918, chr14:39442503, chr14:44156407, chr14:44156411, chr14:44156431, chr14:44379746, chr14:44379797, chr14:53956630, chr14:53956642, chr14:53956653, chr14:53956667, chr14:56506990, chr14:56534824, chr14:56832505, chr14:56992482, chr14:56992483, chr14:61348113, chr14:62736524, chr14:63064707, chr14:63114304, chr14:63114311, chr14:63114337, chr14:64741044, chr14:64942593, chr14:64942636, chr14:67241487, chr14:88791865, chr14:88791879, chr14:104827290, chr14:104895812, chr14:104895822, chr15:22702324, chr15:43776557, chr15:43776576, chr15:53791638, chr16:64387, chr16:561080, chr16:561087, chr16:677534, chr16:2148616, chr16:4260566, chr16:14303673, chr16:14303701, chr16:14303702, chr16:14303720, chr16:19522006, chr16:52395111, chr16:52395146, chr16:52504927, chr16:52504937, chr16:52504992, chr16:52621872, chr16:56191818, chr16:58500253, chr16:58500281, chr16:58500286, chr16:67666791, chr16:67666821, chr16:67666825, chr16:67666999, chr16:67667017, chr16:67667021, chr16:71626053, chr16:84312964, chr16:84312972, chr16:84312978, chr16:84519935, chr16:84659693, chr16:84842521, chr16:85449391, chr16:85449403, chr16:85449420, chr16:86467633, chr16:88291496, chr16:88302508, chr16:88737568, chr17:4263552, chr17:4449947, chr17:7044006, chr17:17403801, chr17:17403831, chr17:19379152, chr17:19379174, chr17:19379191, chr17:29176890, chr17:29565877, chr17:29565896, chr17:29565920, chr17:31561710, chr17:41527810, chr17:42951031, chr17:43720600, chr17:48892861, chr17:65625809, chr17:68870337, chr17:74213330, chr17:74961013, chr17:74961036, chr17:74972136, chr17:79794767, chr17:81397114, chr17:81397126, chr17:81397150, chr17:81514240, chr17:81902419, chr17:81902429, chr17:81902430, chr17:81902433, chr17:81902434, chr17:81902440, chr17:81902441, chr18:6929505, chr18:7327489, chr18:7327495, chr18:32928012, chr18:32928017, chr18:32928020, chr18:32928024, chr18:33167723, chr18:33167727, chr18:33225321, chr18:33317997, chr18:33318065, chr18:33570344, chr18:34609374, chr18:34639003, chr18:38714972, chr18:38714994, chr18:43102815, chr18:47748194, chr18:59148758, chr18:59148765, chr18:63207225, chr18:63207233, chr18:63207260, chr18:71409912, chr18:71652314, chr18:71652318, chr18:72662276, chr18:72677583, chr18:76446564, chr18:76446573, chr18:76446574, chr18:76446612, chr18:76472706, chr18:76580424, chr18:76590712, chr18:76590755, chr18:76590771, chr18:77020807, chr18:77132839, chr18:79334799, chr19:460731, chr19:460763, chr19:511206, chr19:511219, chr19:537165, chr19:1082036, chr19:1082073, chr19:1082079, chr19:1083180, chr19:2624624, chr19:4147445, chr19:4566632, chr19:4566647, chr19:4955146, chr19:6464556, chr19:6551811, chr19:6583884, chr19:7115981, chr19:7904264, chr19:9953412, chr19:9953424, chr19:9961699, chr19:9966503, chr19:9966579, chr19:9966586, chr19:9997385, chr19:10625441, chr19:10625699, chr19:11418683, chr19:13099153, chr19:13248768, chr19:14433259, chr19:15195814, chr19:15195823, chr19:15195830, chr19:15195831, chr19:15195838, chr19:15195844, chr19:15195847, chr19:15195851, chr19:17041847, chr19:17251851, chr19:28293220, chr19:29892627, chr19:33260980, chr19:33393584, chr19:36008846, chr19:36009562, chr19:42242259, chr19:43757320, chr19:44796859, chr19:45444316, chr19:45598430, chr19:46016118, chr19:46016119, chr19:46016123, chr19:46016124, chr19:46016125, chr19:46016126, chr19:46016130, chr19:46016136, chr19:46016138, chr19:46016139, chr19:46016142, chr19:46016144, chr19:46016145, chr19:46016146, chr19:46016147, chr19:46016148, chr19:46016149, chr19:46016465, chr19:48752569, chr19:48752624, chr19:48752637, chr19:48753115, chr19:48753117, chr19:48753159, chr19:48753363, chr19:48753390, chr19:50417522, chr19:50418925, chr19:51030848, chr19:51077450, chr19:52028350, chr19:53991315, chr19:55374611, chr19:55554857, chr2:3303753, chr2:4107720, chr2:4798818, chr2:6987052, chr2:7032109, chr2:8457740, chr2:14507507, chr2:25190664, chr2:47369968.


In some embodiments, methylation status of various methylation sites (e.g., methylation sites of Tables 1, 2.3.4.5.6.7, 8, 9, 10, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 26, 27, 28, 29, and/or 30) is analyzed from tumor DNA from the subject. In some embodiments, tumor DNA is obtained or derived from a tissue sample from the subject. In some embodiments, tumor DNA is obtained or derived from a blood sample from a subject. In some embodiments, tumor DNA is obtained or derived from a plasma sample from a subject. In some embodiments, the tumor DNA is circulating tumor DNA (ctDNA).


Following classification of a subject as having SCLC-A, SCLC-N, SCLC-P, or SCLC-I, the subject may be administered one or more cancer therapies. Example cancer therapies useful for treatment of specific SCLC subtypes are described elsewhere herein.


III. Detection, Diagnosis, and Monitoring

Aspects of the present disclosure comprise diagnosis of a subject with small cell lung cancer (SCLC). In some embodiments, disclosed are methods for diagnosing a subject with SCLC. In some embodiments, disclosed are methods for identifying a subject with cancer as having SCLC. For example, certain aspects are directed to methods for identifying a subject as having SCLC comprising determining the subject to have differential methylation of one or more methylation sites of Table 13, based on analysis of DNA from the subject. A subject may be a subject having cancer. A subject may be as subject suspected of having cancer. A subject may have an unknown cancer type. A subject may have lung cancer of an unknown type, where the disclosed methods are useful in identifying the subject as having SCLC and not as having non-small cell lung cancer (NSCLC).


In some embodiments, the subject is determined to have SCLC based on analysis of at least or at most 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, and 27 methylation sites of Table 13. Methylation sites may be analyzed from DNA from the subject. In some embodiments, the DNA is tumor DNA. In some embodiments, the DNA is circulating tumor DNA (ctDNA). Analyses of each and every combination of methylation sites from Table 13 are contemplated herein. For example, a subject may be determined to have differential methylation of 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, or 27 of the methylation sites of Table 13, thereby identifying the subject as having SCLC. In some embodiments, the disclosed methods comprise determining, based on analysis of tumor DNA from a subject, the subject to have differential methylation at cg09052983, cg03196720, cg03851835, cg23847017, cg06029700, cg16955166, cg00956142, cg07101841, cg22099241, cg00233633, cg02339793, cg07093324, cg18166947, cg21055554, cg18474885, cg19166875, cg24473500, cg22234930, cg23715728, cg04650676, cg00134210, cg04387396, cg01807820, cg15689991, cg03577157, cg11708454, and/or cg08962271.


After identifying the subject as having SCLC, the subject may be administered one or more SCLC therapies. SCLC therapies are known in the art, and certain examples are described herein.


Additional aspects of the disclosure relate to evaluation of tumor burden in a subject having SCLC, monitoring SCLC treatment efficacy, and evaluating and adjusting SCLC treatment strategy. As described herein, certain methylation sites, including the methylation sites of Table 24 (chr5:77844815, chr5:77844832, chr5:77844821, chr5:132257679, chr16:49280789, chr21:34670607, chr21:34670604, chr21:34670609, chr6:108176627, chr10:71638792, chr5:132257648, chr5:132257653, chr5:132257685, chr5:132257670, chr5:138274351, chr8:22139065, chr5:132257664, chr5:132257652, chr5:132257666, chr3:38039198, chr9:137591221, chr9:131444459, chr6:108176609, chr5:132257661, chr5:132257650, chr5:132257703, chr5:132257682, chr5:178860732, chr5:132257676, chr20:22582930, chr2:10043081, chr2:98347974, chr5:132257649, chr5:178860742, chr5:138274357, chr5:138274360, chr10:75408778, chr5:132257647, chr5:132257637, chr6:108176612, chr22:50251762, chr21:34669575) correlate with general tumor burden in SCLC and thus can be used to evaluate tumor burden and monitor treatment response. Accordingly, disclosed are methods comprising determining, from DNA from a subject, a methylation status of two or more methylation sites of Table 24. A methylation status may be determined for at least or at most 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, or 42 of the methylation sites of Table 24. In some aspects, disclosed are methods comprising determining a methylation status of at least or at most 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, or 42 of the following methylation sites: chr5:77844815, chr5:77844832, chr5:77844821, chr5:132257679, chr16:49280789, chr21:34670607, chr21:34670604, chr21:34670609, chr6:108176627, chr10:71638792, chr5:132257648, chr5:132257653, chr5:132257685, chr5:132257670, chr5:138274351, chr8:22139065, chr5:132257664, chr5:132257652, chr5:132257666, chr3:38039198, chr9:137591221, chr9:131444459, chr6:108176609, chr5:132257661, chr5:132257650, chr5:132257703, chr5:132257682, chr5:178860732, chr5:132257676, chr20:22582930, chr2:10043081, chr2:98347974, chr5:132257649, chr5:178860742, chr5:138274357, chr5:138274360, chr10:75408778, chr5:132257647, chr5:132257637, chr6:108176612, chr22:50251762, and chr21:34669575. It is specifically contemplated that any one or more of these methylation sites may be excluded from certain embodiments.


In some aspects, the disclosed methods comprise evaluating tumor DNA from a subject having SCLC who is currently receiving or has previously received SCLC therapy. Also disclosed are treatment methods comprising determining a methylation level of two or more methylation sites of Table 24, administering a cancer therapy to a subject, then determining an additional methylation level of the same two or more methylation sites of Table 24 and comparing the methylation levels. A decreased methylation level may indicate a reduced tumor burden and, thus, that the cancer therapy is effective. An increased or unchanged methylation level may indicate an increased or unchanged tumor burden and, thus, that the cancer therapy is ineffective. Accordingly, if a decreased methylation level is measured following treatment, the same treatment may be continued, while if an increased or unchanged methylation level is measured following treatment, a different treatment may be selected and administered.


IV. Sample Preparation

In certain aspects, methods involve obtaining a sample (also “biological sample”) from a subject. The methods of obtaining provided herein may include methods of biopsy such as fine needle aspiration, core needle biopsy, vacuum assisted biopsy, incisional biopsy, excisional biopsy, punch biopsy, shave biopsy, or skin biopsy. In certain embodiments the sample is obtained from a biopsy from lung tissue by any of the biopsy methods previously mentioned. In other embodiments the sample may be obtained from any of the tissues provided herein that include but are not limited to non-cancerous or cancerous tissue and non-cancerous or cancerous tissue from the serum, gall bladder, mucosal, skin, heart, lung, breast, pancreas, blood, liver, muscle, kidney, smooth muscle, bladder, colon, intestine, brain, prostate, esophagus, or thyroid tissue. Alternatively, the sample may be obtained from any other source including but not limited to blood, plasma, serum, pleural fluid, pericardial fluid, spinal fluid, ascitic fluid, sweat, hair follicle, buccal tissue, tears, menses, feces, or saliva. In certain aspects of the current methods, any medical professional such as a doctor, nurse or medical technician may obtain a biological sample for testing. Yet further, the biological sample can be obtained without the assistance of a medical professional.


A sample may include but is not limited to, tissue, cells, or biological material from cells or derived from cells of a subject. The biological sample may be a heterogeneous or homogeneous population of cells or tissues. A sample may also include a sample devoid of cells, for example a cell-free sample comprising cell-free nucleic acid, such as a serum sample. The biological sample may be obtained using any method known to the art that can provide a sample suitable for the analytical methods described herein. The sample may be obtained by non-invasive methods including but not limited to: scraping of the skin or cervix, swabbing of the cheek, saliva collection, urine collection, blood collection, plasma collection, feces collection, collection of menses, tears, or semen.


The sample may be obtained by methods known in the art. In certain embodiments the samples are obtained by biopsy. In other embodiments the sample is obtained by swabbing, endoscopy, scraping, phlebotomy, or any other methods known in the art. In some cases, the sample may be obtained, stored, or transported using components of a kit of the present methods. In some cases, multiple samples, such as multiple lung samples or multiple blood or plasma samples, may be obtained for diagnosis by the methods described herein. In other cases, multiple samples, such as one or more samples from one tissue type (for example lung) and one or more samples from another specimen (for example serum) may be obtained for diagnosis by the methods. In some cases, multiple samples such as one or more samples from one tissue type (e.g. lung) and one or more samples from another specimen (e.g. serum) may be obtained at the same or different times.


In some embodiments, a biological sample analyzed here is a liquid sample. In some embodiments, the sample is a blood sample. In some embodiments, the sample is a plasma sample. In some embodiments, the sample is a serum sample. A liquid sample may comprise tumor DNA. As discussed herein, “tumor DNA” describes any DNA derived from a tumor, and includes tumor DNA derived from a solid tumor sample (e.g., a solid biopsy) and tumor DNA obtained from cell-free sample (e.g., plasma, blood, etc.). Tumor DNA from a liquid sample may be cell-free DNA (cfDNA) and/or DNA from circulating tumor cells. As described herein. “circulating tumor DNA,” or “ctDNA” describes tumor DNA obtained from blood or a blood component (e.g., plasma, serum) from a subject. Tumor DNA, including circulating tumor DNA (ctDNA), may be isolated from a sample and analysed as disclosed herein (e.g., by sequcing such as bisulfite sequencing).


In some embodiments the biological sample may be obtained by a physician, nurse, or other medical professional such as a medical technician, endocrinologist, cytologist, phlebotomist, radiologist, or a pulmonologist. The medical professional may indicate the appropriate test or assay to perform on the sample. In certain aspects a molecular profiling business may consult on which assays or tests are most appropriately indicated. In further aspects of the current methods, the patient or subject may obtain a biological sample for testing without the assistance of a medical professional, such as obtaining a whole blood sample, a urine sample, a fecal sample, a buccal sample, or a saliva sample.


In other cases, the sample is obtained by an invasive procedure including but not limited to: biopsy, needle aspiration, endoscopy, or phlebotomy. The method of needle aspiration may further include fine needle aspiration, core needle biopsy, vacuum assisted biopsy, or large core biopsy. In some embodiments, multiple samples may be obtained by the methods herein to ensure a sufficient amount of biological material.


In some embodiments of the present methods, the molecular profiling business may obtain the biological sample from a subject directly, from a medical professional, from a third party, or from a kit provided by a molecular profiling business or a third party. In some cases, the biological sample may be obtained by the molecular profiling business after the subject, a medical professional, or a third party acquires and sends the biological sample to the molecular profiling business. In some cases, the molecular profiling business may provide suitable containers, and excipients for storage and transport of the biological sample to the molecular profiling business.


In some embodiments of the methods described herein, a medical professional need not be involved in the initial diagnosis or sample acquisition. An individual may alternatively obtain a sample through the use of an over the counter (OTC) kit. An OTC kit may contain a means for obtaining said sample as described herein, a means for storing said sample for inspection, and instructions for proper use of the kit. In some cases, molecular profiling services are included in the price for purchase of the kit. In other cases, the molecular profiling services are billed separately. A sample suitable for use by the molecular profiling business may be any material containing tissues, cells, nucleic acids, genes, gene fragments, expression products, gene expression products, or gene expression product fragments of an individual to be tested. Methods for determining sample suitability and/or adequacy are provided.


In some embodiments, the subject may be referred to a specialist such as an oncologist, surgeon, or endocrinologist. The specialist may likewise obtain a biological sample for testing or refer the individual to a testing center or laboratory for submission of the biological sample. In some cases the medical professional may refer the subject to a testing center or laboratory for submission of the biological sample. In other cases, the subject may provide the sample. In some cases, a molecular profiling business may obtain the sample.


V. Assay Methods

A. Detection of Methylated DNA


Aspects of the methods include assaying nucleic acids (e.g., tumor DNA) to determine expression levels and/or methylation levels of nucleic acids. In some embodiments, disclosed are methods comprising determining a methylation status of one or more methylation sites from methylated DNA. The disclosed methods may comprise determining a subject (i.e., DNA from a subject such as tumor DNA) to have differential methylation at one or more methylation sites. As used herein, “differential methylation” of a methylation site describes a significant difference in methylation status of the methylation site in a sample (e.g., a sample comprising tumor DNA from a subject having cancer) as compared to a control or reference (e.g., DNA from a healthy subject). For example, in some embodiments, a methylation site from a sample comprising tumor DNA has significantly increased methylation levels compared to the same methylation site from control (e.g., healthy, non-tumor) DNA. In some embodiments, a methylation site from a sample comprising tumor DNA has significantly decreased methylation levels compared to the same methylation site from control (e.g., healthy, non-tumor) DNA. Assays for the detection of methylated DNA are known in the art. Methylated DNA includes, for example, methylated circulating tumor DNA. Certain, non-limiting examples of such methods are described herein.


1. HPLC-UV


The technique of HPLC-UV (high performance liquid chromatography-ultraviolet), developed by Kuo and colleagues in 1980 (described further in Kuo K. C. et al., Nucleic Acids Res. 1980; 8:4763-4776, which is herein incorporated by reference) can be used to quantify the amount of deoxycytidine (dC) and methylated cytosines (5 mC) present in a hydrolysed DNA sample. The method includes hydrolyzing the DNA into its constituent nucleoside bases, the 5 mC and dC bases are separated chromatographically and, then, the fractions are measured. Then, the 5 mC/dC ratio can be calculated for each sample, and this can be compared between the experimental and control samples.


2. LC-MS/MS


Liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS) is an high-sensitivity approach to HPLC-UV, which requires much smaller quantities of the hydrolysed DNA sample. In the case of mammalian DNA, of which ˜2%-5% of all cytosine residues are methylated, LC-MS/MS has been validated for detecting levels of methylation levels ranging from 0.05%-10%, and it can confidently detect differences between samples as small as ˜0.25% of the total cytosine residues, which corresponds to ˜5% differences in global DNA methylation. The procedure routinely requires 50-100 ng of DNA sample, although much smaller amounts (as low as 5 ng) have been successfully profiled. Another major benefit of this method is that it is not adversely affected by poor-quality DNA (e.g., DNA derived from FFPE samples).


3. ELISA-Based Methods


There are several commercially available kits, all enzyme-linked immunosorbent assay (ELISA) based, that enable the quick assessment of DNA methylation status. These assays include Global DNA Methylation ELISA, available from Cell Biolabs; Imprint Methylated DNA Quantification kit (sandwich ELISA), available from Sigma-Aldrich; EpiSeeker methylated DNA Quantification Kit, available from abcam; Global DNA Methylation Assay—LINE-1, available from Active Motif: 5-mC DNA ELISA Kit, available from Zymo Research: MethylFlash Methylated DNAS-mC Quantification Kit and MethylFlash Methylated DNAS-mC Quantification Kit, available from Epigentek.


Briefly, the DNA sample is captured on an ELISA plate, and the methylated cytosines are detected through sequential incubations steps with: (1) a primary antibody raised against 5 Mc; (2) a labelled secondary antibody: and then (3) colorimetric/fluorometric detection reagents.


The Global DNA Methylation Assay—LINE-1 specifically determines the methylation levels of LINE-1 (long interspersed nuclear elements-1) retrotransposons, of which ˜17% of the human genome is composed. These are well established as a surrogate for global DNA methylation. Briefly, fragmented DNA is hybridized to biotinylated LINE-1 probes, which are then subsequently immobilized to a streptavidin-coated plate. Following washing and blocking steps, methylated cytosines are quantified using an anti-5 mC antibody, HRP-conjugated secondary antibody and chemiluminescent detection reagents. Samples are quantified against a standard curve generated from standards with known LINE-1 methylation levels. The manufacturers claim the assay can detect DNA methylation levels as low as 0.5%. Thus, by analyzing a fraction of the genome, it is possible to achieve better accuracy in quantification.


4. LINE-1 Pyrosequencing


Levels of LINE-1 methylation can alternatively be assessed by another method that involves the bisulfite conversion of DNA, followed by the PCR amplification of LINE-1 conservative sequences. The methylation status of the amplified fragments is then quantified by pyrosequencing, which is able to resolve differences between DNA samples as small as ˜5%. Even though the technique assesses LINE-1 elements and therefore relatively few CpG sites, this has been shown to reflect global DNA methylation changes very well. The method is particularly well suited for high throughput analysis of cancer samples, where hypomethylation is very often associated with poor prognosis. This method is particularly suitable for human DNA, but there are also versions adapted to rat and mouse genomes.


5. AFLP and RFLP


Detection of fragments that are differentially methylated could be achieved by traditional PCR-based amplification fragment length polymorphism (AFLP), restriction fragment length polymorphism (RFLP) or protocols that employ a combination of both.


6. LUMA


The LUMA (luminometric methylation assay) technique utilizes a combination of two DNA restriction digest reactions performed in parallel and subsequent pyrosequencing reactions to fill-in the protruding ends of the digested DNA strands. One digestion reaction is performed with the CpG methylation-sensitive enzyme HpaII; while the parallel reaction uses the methylation-insensitive enzyme MspI, which will cut at all CCGG sites. The enzyme EcoRI is included in both reactions as an internal control. Both MspI and HpaII generate 5′-CG overhangs after DNA cleavage, whereas EcoRI produces 5′-AATT overhangs, which are then filled in with the subsequent pyrosequencing-based extension assay. Essentially, the measured light signal calculated as the HpaII/MspI ratio is proportional to the amount of unmethylated DNA present in the sample. As the sequence of nucleotides that are added in pyrosequencing reaction is known, the specificity of the method is very high and the variability is low, which is essential for the detection of small changes in global methylation. LUMA requires only a relatively small amount of DNA (250-500 ng), demonstrates little variability and has the benefit of an internal control to account for variability in the amount of DNA input.


7. Bisulfite Sequencing


The bisulfite treatment of DNA mediates the deamination of cytosine into uracil, and these converted residues will be read as thymine, as determined by PCR-amplification and subsequent Sanger sequencing analysis. However, 5 mC residues are resistant to this conversion and, so, will remain read as cytosine. Thus, comparing the Sanger sequencing read from an untreated DNA sample to the same sample following bisulfite treatment enables the detection of the methylated cytosines. With the advent of next-generation sequencing (NGS) technology, this approach can be extended to DNA methylation analysis across an entire genome. To ensure complete conversion of non-methylated cytosines, controls may be incorporated for bisulfite reactions.


Whole genome bisulfite sequencing (WGBS) is similar to whole genome sequencing, except for the additional step of bisulfite conversion. Sequencing of the 5 mC-enriched fraction of the genome is not only a less expensive approach, but it also allows one to increase the sequencing coverage and, therefore, precision in revealing differentially-methylated regions. Sequencing could be done using any existing NGS platform; Illumina and Life Technologies both offer kits for such analysis.


Bisulfite sequencing methods include reduced representation bisulfite sequencing (RRBS), where only a fraction of the genome is sequenced. In RRBS, enrichment of CpG-rich regions is achieved by isolation of short fragments after MspI digestion that recognizes CCGG sites (and it cut both methylated and unmethylated sites). It ensures isolation of ˜85% of CpG islands in the human genome. Then, the same bisulfite conversion and library preparation is performed as for WGBS. The RRBS procedure normally requires ˜100 ng-1 μg of DNA.


8. Methods that Exclude Bisulfite Conversion


In some aspects, direct detection of modified bases without bisulfite conversion may be used to detect methylation. For example, Pacific Biosciences company has developed a way to detect methylated bases directly by monitoring the kinetics of polymerase during single molecule sequencing and offers a commercial product for such sequencing (further described in Flusberg B. A., et al., Nat. Methods. 2010; 7:461-465, which is herein incorporated by reference). Other methods include nanopore-based single-molecule real-time sequencing technology (SMRT), which is able to detect modified bases directly (described in Laszlo A. H. et al., Proc. Natl. Acad. Sci. USA. 2013 and Schreiber J., et al., Proc. Natl. Acad. Sci. USA. 2013, which are herein incorporated by reference).


9. Array or Bead Hybridization


Methylated DNA fractions of the genome, usually obtained by immunoprecipitation, could be used for hybridization with microarrays. Currently available examples of such arrays include: the Human CpG Island Microarray Kit (Agilent), the GeneChip Human Promoter 1.0R Array and the GeneChip Human Tiling 2.0R Array Set (Affymetrix).


The search for differentially-methylated regions using bisulfite-converted DNA could be done with the use of different techniques. Some of them are easier to perform and analyse than others, because only a fraction of the genome is used. The most pronounced functional effect of DNA methylation occurs within gene promoter regions, enhancer regulatory elements and 3′ untranslated regions (3′UTRs). Assays that focus on these specific regions, such as the Infinium HumanMethylation450 Bead Chip array by Illumina, can be used. The arrays can be used to detect methylation status of genes, including miRNA promoters, 5′ UTR, 3′ UTR, coding regions (˜17 CpG per gene) and island shores (regions ˜2 kb upstream of the CpG islands).


Briefly, bisulfite-treated genomic DNA is mixed with assay oligos, one of which is complimentary to uracil (converted from original unmethylated cytosine), and another is complimentary to the cytosine of the methylated (and therefore protected from conversion) site. Following hybridization, primers are extended and ligated to locus-specific oligos to create a template for universal PCR. Finally, labelled PCR primers are used to create detectable products that are immobilized to bar-coded beads, and the signal is measured. The ratio between two types of beads for each locus (individual CpG) is an indicator of its methylation level.


It is possible to purchase kits that utilize the extension of methylation-specific primers for validation studies. In the VeraCode Methylation assay from Illumina, 96 or 384 user-specified CpG loci are analysed with the GoldenGate Assay for Methylation. Differently from the BeadChip assay, the VeraCode assay requires the BeadXpress Reader for scanning.


10. Methyl-Sensitive Cut Counting: Endonuclease Digestion Followed by Sequencing


As an alternative to sequencing a substantial amount of methylated (or unmethylated) DNA, one could generate snippets from these regions and map them back to the genome after sequencing. The technique of serial analysis of gene expression (SAGE) has been adapted for this purpose and is known as methylation-specific digital karyotyping, as well as a similar technique, called methyl-sensitive cut counting (MSCC).


In summary, in all of these methods, methylation-sensitive endonuclease(s), e.g., HpaII is used for initial digestion of genomic DNA in unmethylated sites followed by adaptor ligation that contains the site for another digestion enzyme that is cut outside of its recognized site, e.g., EcoP15I or MmeI. These ways, small fragments are generated that are located in close proximity to the original HpaII site. Then. NGS and mapping to the genome are performed. The number of reads for each HpaII site correlates with its methylation level.


A number of restriction enzymes have been discovered that use methylated DNA as a substrate (methylation-dependent endonucleases). Most of them were discovered and are sold by SibEnzyme: BisI, BIsI, GlaI. GluI, KroI, MteI, PcsI, PkrI. The unique ability of these enzymes to cut only methylated sites has been utilized in the method that achieved selective amplification of methylated DNA. Three methylation-dependent endonucleases that are available from New England Biolabs (FspEI, MspJI and LpnPI) are type IIS enzymes that cut outside of the recognition site and, therefore, are able to generate snippets of 32 bp around the fully-methylated recognition site that contains CpG. These short fragments could be sequences and aligned to the reference genome. The number of reads obtained for each specific 32-bp fragment could be an indicator of its methylation level. Similarly, short fragments could be generated from methylated CpG islands with Escherichia coli's methyl-specific endonuclease McrBC, which cuts DNA between two half-sites of (G/A) mC that are lying within 50 bp-3000 bp from each other. This is a very useful tool for isolation of methylated CpG islands that again can be combined with NGS. Being bisulfite-free, these three approaches have a great potential for quick whole genome methylome profiling.


B. Sequencing


DNA, including bisulfite-converted DNA, may be used for amplification of a region of interest followed by sequencing. Primers may designed around a methylation site of interest and used for PCR amplification of bisulfite-converted DNA. The resulting PCR products may be cloned and sequenced. Accordingly, aspects of the disclosure may include sequencing nucleic acids to detect methylation of nucleic acids and/or biomarkers. In some embodiments, the methods of the disclosure include a sequencing method. Example sequencing methods include those described below.


1. Massively parallel signature sequencing (MPSS).


The first of the next-generation sequencing technologies, massively parallel signature sequencing (or MPSS), was developed in the 1990s at Lynx Therapeutics. MPSS was a bead-based method that used a complex approach of adapter ligation followed by adapter decoding, reading the sequence in increments of four nucleotides. This method made it susceptible to sequence-specific bias or loss of specific sequences. Because the technology was so complex. MPSS was only performed ‘in-house’ by Lynx Therapeutics and no DNA sequencing machines were sold to independent laboratories. Lynx Therapeutics merged with Solexa (later acquired by Illumina) in 2004, leading to the development of sequencing-by-synthesis, a simpler approach acquired from Manteia Predictive Medicine. The essential properties of the MPSS output were typical of later “next-generation” data types, including hundreds of thousands of short DNA sequences. In the case of MPSS, these were typically used for sequencing cDNA for measurements of gene expression levels. Indeed, the powerful Illumina HiSeq2000, HiSeq2500 and MiSeq systems are based on MPSS.


2. Polony Sequencing.


The Polony sequencing method, developed in the laboratory of George M. Church at Harvard, was among the first next-generation sequencing systems and was used to sequence a full genome in 2005. It combined an in vitro paired-tag library with emulsion PCR, an automated microscope, and ligation-based sequencing chemistry to sequence an E. coli genome at an accuracy of >99.9999% and a cost approximately 1/9 that of Sanger sequencing.


3. 454 Pyrosequencing.


A parallelized version of pyrosequencing was developed by 454 Life Sciences, which has since been acquired by Roche Diagnostics. The method amplifies DNA inside water droplets in an oil solution (emulsion PCR), with each droplet containing a single DNA template attached to a single primer-coated bead that then forms a clonal colony. The sequencing machine contains many picoliter-volume wells each containing a single bead and sequencing enzymes. Pyrosequencing uses luciferase to generate light for detection of the individual nucleotides added to the nascent DNA, and the combined data are used to generate sequence read-outs. This technology provides intermediate read length and price per base compared to Sanger sequencing on one end and Solexa and SOLiD on the other.


4. Illumina (Solexa) Sequencing.


Solexa, now part of Illumina, developed a sequencing method based on reversible dye-terminators technology, and engineered polymerases, that it developed internally. The terminated chemistry was developed internally at Solexa and the concept of the Solexa system was invented by Balasubramanian and Klennerman from Cambridge University's chemistry department. In 2004, Solexa acquired the company Manteia Predictive Medicine in order to gain a massivelly parallel sequencing technology based on “DNA Clusters”, which involves the clonal amplification of DNA on a surface. The cluster technology was co-acquired with Lynx Therapeutics of California. Solexa Ltd. later merged with Lynx to form Solexa Inc.


In this method, DNA molecules and primers are first attached on a slide and amplified with polymerase so that local clonal DNA colonies, later coined “DNA clusters”, are formed. To determine the sequence, four types of reversible terminator bases (RT-bases) are added and non-incorporated nucleotides are washed away. A camera takes images of the fluorescently labeled nucleotides, then the dye, along with the terminal 3′ blocker, is chemically removed from the DNA, allowing for the next cycle to begin. Unlike pyrosequencing, the DNA chains are extended one nucleotide at a time and image acquisition can be performed at a delayed moment, allowing for very large arrays of DNA colonies to be captured by sequential images taken from a single camera.


Decoupling the enzymatic reaction and the image capture allows for optimal throughput and theoretically unlimited sequencing capacity. With an optimal configuration, the ultimately reachable instrument throughput is thus dictated solely by the analog-to-digital conversion rate of the camera, multiplied by the number of cameras and divided by the number of pixels per DNA colony required for visualizing them optimally (approximately 10 pixels/colony). In 2012, with cameras operating at more than 10 MHz A/D conversion rates and available optics, fluidics and enzymatics, throughput can be multiples of 1 million nucleotides/second, corresponding roughly to one human genome equivalent at 1× coverage per hour per instrument, and one human genome re-sequenced (at approx. 30×) per day per instrument (equipped with a single camera).


5. Solid Sequencing.


Applied Biosystems' (now a Thermo Fisher Scientific brand) SOLiD technology employs sequencing by ligation. Here, a pool of all possible oligonucleotides of a fixed length are labeled according to the sequenced position. Oligonucleotides are annealed and ligated; the preferential ligation by DNA ligase for matching sequences results in a signal informative of the nucleotide at that position. Before sequencing, the DNA is amplified by emulsion PCR. The resulting beads, each containing single copies of the same DNA molecule, are deposited on a glass slide. The result is sequences of quantities and lengths comparable to Illumina sequencing. This sequencing by ligation method has been reported to have some issue sequencing palindromic sequences.


6. Ion Torrent Semiconductor Sequencing.


Ion Torrent Systems Inc. (now owned by Thermo Fisher Scientific) developed a system based on using standard sequencing chemistry, but with a novel, semiconductor based detection system. This method of sequencing is based on the detection of hydrogen ions that are released during the polymerization of DNA, as opposed to the optical methods used in other sequencing systems. A microwell containing a template DNA strand to be sequenced is flooded with a single type of nucleotide. If the introduced nucleotide is complementary to the leading template nucleotide it is incorporated into the growing complementary strand. This causes the release of a hydrogen ion that triggers a hypersensitive ion sensor, which indicates that a reaction has occurred. If homopolymer repeats are present in the template sequence multiple nucleotides will be incorporated in a single cycle. This leads to a corresponding number of released hydrogens and a proportionally higher electronic signal.


7. DNA Nanoball Sequencing.


DNA nanoball sequencing is a type of high throughput sequencing technology used to determine the entire genomic sequence of an organism. The company Complete Genomics uses this technology to sequence samples submitted by independent researchers. The method uses rolling circle replication to amplify small fragments of genomic DNA into DNA nanoballs. Unchained sequencing by ligation is then used to determine the nucleotide sequence. This method of DNA sequencing allows large numbers of DNA nanoballs to be sequenced per run and at low reagent costs compared to other next generation sequencing platforms. However, only short sequences of DNA are determined from each DNA nanoball which makes mapping the short reads to a reference genome difficult. This technology has been used for multiple genome sequencing projects.


8. Heliscope Single Molecule Sequencing.


Heliscope sequencing is a method of single-molecule sequencing developed by Helicos Biosciences. It uses DNA fragments with added poly-A tail adapters which are attached to the flow cell surface. The next steps involve extension-based sequencing with cyclic washes of the flow cell with fluorescently labeled nucleotides (one nucleotide type at a time, as with the Sanger method). The reads are performed by the Heliscope sequencer. The reads are short, up to 55 bases per run, but recent improvements allow for more accurate reads of stretches of one type of nucleotides. This sequencing method and equipment were used to sequence the genome of the M13 bacteriophage.


9. Single Molecule Real Time (SMRT) Sequencing.


SMRT sequencing is based on the sequencing by synthesis approach. The DNA is synthesized in zero-mode wave-guides (ZMWs)—small well-like containers with the capturing tools located at the bottom of the well. The sequencing is performed with use of unmodified polymerase (attached to the ZMW bottom) and fluorescently labelled nucleotides flowing freely in the solution. The wells are constructed in a way that only the fluorescence occurring by the bottom of the well is detected. The fluorescent label is detached from the nucleotide at its incorporation into the DNA strand, leaving an unmodified DNA strand. According to Pacific Biosciences, the SMRT technology developer, this methodology allows detection of nucleotide modifications (such as cytosine methylation). This happens through the observation of polymerase kinetics. This approach allows reads of 20,000 nucleotides or more, with average read lengths of 5 kilobases.


VI. Cancer Therapy

In some embodiments, the disclosed methods comprise administering a cancer therapy to a subject or patient. The cancer therapy may be chosen based on expression level measurements, methylation status measurements, and/or other factors such as a clinical risk score calculated for the subject. In some embodiments, the cancer therapy comprises a local cancer therapy. In some embodiments, the cancer therapy excludes a systemic cancer therapy. In some embodiments, the cancer therapy excludes a local therapy. In some embodiments, the cancer therapy comprises a local cancer therapy without the administration of a system cancer therapy. In some embodiments, the cancer therapy comprises an immunotherapy, which may be a checkpoint inhibitor therapy. Any of these cancer therapies may also be excluded. Combinations of these therapies may also be administered.


The term “cancer,” as used herein, may be used to describe a solid tumor, metastatic cancer, or non-metastatic cancer. In certain embodiments, the cancer may originate in the bladder, blood, bone, bone marrow, brain, breast, colon, esophagus, duodenum, small intestine, large intestine, colon, rectum, anus, gum, head, kidney, liver, lung, nasopharynx, neck, ovary, pancreas, prostate, skin, stomach, testis, tongue, or uterus. In some embodiments, the cancer is recurrent cancer. In some embodiments, the cancer is Stage I cancer. In some embodiments, the cancer is Stage II cancer. In some embodiments, the cancer is Stage III cancer. In some embodiments, the cancer is Stage IV cancer.


In some embodiments, disclosed are methods for treating cancer originating from the lung. In some embodiments, the cancer is lung cancer. In some embodiments, the cancer is small cell lung cancer (SCLC). In some embodiments, disclosed are methods for treating high-grade neuroendocrine carcinomas.


A. Chemotherapies


In some embodiments, methods of the disclosure comprise administering a chemotherapy. Suitable classes of chemotherapeutic agents include (a) Alkylating Agents, such as nitrogen mustards (e.g., mechlorethamine, cylophosphamide, ifosfamide, melphalan, chlorambucil), ethylenimines and methylmelamines (e.g., hexamethylmelamine, thiotepa), alkyl sulfonates (e.g., busulfan), nitrosoureas (e.g., carmustine, lomustine, chlorozoticin, streptozocin) and triazines (e.g., dicarbazine), (b) Antimetabolites, such as folic acid analogs (e.g., methotrexate), pyrimidine analogs (e.g., 5-fluorouracil, floxuridine, cytarabine, azauridine) and purine analogs and related materials (e.g., 6-mercaptopurine, 6-thioguanine, pentostatin), (c) Natural Products, such as vinca alkaloids (e.g., vinblastine, vincristine), epipodophylotoxins (e.g., etoposide, teniposide), antibiotics (e.g., dactinomycin, daunorubicin, doxorubicin, bleomycin, plicamycin and mitoxanthrone), enzymes (e.g., L-asparaginase), and biological response modifiers (e.g., Interferon-α), and (d) Miscellaneous Agents, such as platinum coordination complexes (e.g., cisplatin, carboplatin), substituted ureas (e.g., hydroxyurea), methylhydiazine derivatives (e.g., procarbazine), and adreocortical suppressants (e.g., taxol and mitotane). In some embodiments, cisplatin is a particularly suitable chemotherapeutic agent. Other suitable chemotherapeutic agents include antimicrotubule agents, e.g., Paclitaxel (“Taxol”) and doxorubicin hydrochloride (“doxorubicin”).


Additional suitable chemotherapeutic agents include pyrimidine analogs, such as cytarabine (cytosine arabinoside), 5-fluorouracil (fluouracil; 5-FU) and floxuridine (fluorode-oxyuridine; FudR). 5-FU may be administered to a subject in a dosage of anywhere between about 7.5 to about 1000 mg/m2. Further, 5-FU dosing schedules may be for a variety of time periods, for example up to six weeks, or as determined by one of ordinary skill in the art to which this disclosure pertains.


The amount of the chemotherapeutic agent delivered to the patient may be variable. In one suitable embodiment, the chemotherapeutic agent may be administered in an amount effective to cause arrest or regression of the cancer in a host. In other embodiments, the chemotherapeutic agent may be administered in an amount that is anywhere between 2 to 10,000 fold less than the chemotherapeutic effective dose of the chemotherapeutic agent. For example, the chemotherapeutic agent may be administered in an amount that is about 20 fold less, about 500 fold less or even about 5000 fold less than the chemotherapeutic effective dose of the chemotherapeutic agent. The chemotherapeutics of the disclosure can be tested in vivo for the desired therapeutic activity in combination with the construct, as well as for determination of effective dosages. For example, such compounds can be tested in suitable animal model systems prior to testing in humans, including, but not limited to, rats, mice, chicken, cows, monkeys, rabbits, etc. In vitro testing may also be used to determine suitable combinations and dosages, as described in the examples.


B. Surgery


In some embodiments, the disclosed methods comprise surgery. Approximately 60% of persons with cancer will undergo surgery of some type, which includes preventative, diagnostic or staging, curative, and palliative surgery. Curative surgery includes resection in which all or part of cancerous tissue is physically removed, excised, and/or destroyed and may be used in conjunction with other therapies, such as the treatment of the present embodiments, chemotherapy, radiotherapy, hormonal therapy, gene therapy, immunotherapy, and/or alternative therapies. Tumor resection refers to physical removal of at least part of a tumor. In addition to tumor resection, treatment by surgery includes laser surgery, cryosurgery, electrosurgery, and microscopically-controlled surgery (Mohs' surgery).


Upon excision of part or all of cancerous cells, tissue, or tumor, a cavity may be formed in the body. Treatment may be accomplished by perfusion, direct injection, or local application of the area with an anti-cancer therapy, such as a chemotherapeutic. Such treatment may be repeated, for example, every 1, 2, 3, 4, 5, 6, or 7 days, or every 1, 2, 3, 4, and 5 weeks or every 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, or 12 months. These treatments may be of varying dosages as well.


C. Immunotherapy


In some embodiments, the disclosed methods comprise administration of a cancer immunotherapy. Cancer immunotherapy (sometimes called immuno-oncology, abbreviated IO) is the use of the immune system to treat cancer. Immunotherapies can be categorized as active, passive or hybrid (active and passive). These approaches exploit the fact that cancer cells often have molecules on their surface that can be detected by the immune system, known as tumour-associated antigens (TAAs); they are often proteins or other macromolecules (e.g. carbohydrates). Active immunotherapy directs the immune system to attack tumor cells by targeting TAAs. Passive immunotherapies enhance existing anti-tumor responses and include the use of monoclonal antibodies, lymphocytes and cytokines. Immumotherapies are known in the art, and some are described below. In some embodiments, a cancer immunotherapy is administered to a subject having been determined to have a cancer of the SCLC-I subtype. In some embodiments, a cancer immunotherapy is administered to a subject having been determined to have a cancer of the SCLC-A subtype. In some embodiments, a cancer immunotherapy is administered to a subject having been determined to have a cancer of the SCLC-N subtype. In some embodiments, a cancer immunotherapy is administered to a subject having been determined to have a cancer of the SCLC-P subtype. In some embodiments, a cancer immunotherapy is administered to a subject in combination with one or more additional cancer therapies.


1. Checkpoint Inhibitors and Combination Treatment


Embodiments of the disclosure may include administration of immune checkpoint inhibitors, which are further described below.


a. PD-1, PDL1, and PDL2 Inhibitors


PD-1 can act in the tumor microenvironment where T cells encounter an infection or tumor. Activated T cells upregulate PD-1 and continue to express it in the peripheral tissues. Cytokines such as IFN-gamma induce the expression of PDL1 on epithelial cells and tumor cells. PDL2 is expressed on macrophages and dendritic cells. The main role of PD-1 is to limit the activity of effector T cells in the periphery and prevent excessive damage to the tissues during an immune response. Inhibitors of the disclosure may block one or more functions of PD-1 and/or PDL1 activity.


Alternative names for “PD-1” include CD279 and SLEB2. Alternative names for “PDL1” include B7-H1, B7-4, CD274, and B7-H. Alternative names for “PDL2” include B7-DC, Btdc, and CD273. In some embodiments, PD-1, PDL1, and PDL2 are human PD-1, PDL1 and PDL2.


In some embodiments, the PD-1 inhibitor is a molecule that inhibits the binding of PD-1 to its ligand binding partners. In a specific aspect, the PD-1 ligand binding partners are PDL1 and/or PDL2. In another embodiment, a PDL1 inhibitor is a molecule that inhibits the binding of PDL1 to its binding partners. In a specific aspect, PDL1 binding partners are PD-1 and/or B7-1. In another embodiment, the PDL2 inhibitor is a molecule that inhibits the binding of PDL2 to its binding partners. In a specific aspect, a PDL2 binding partner is PD-1. The inhibitor may be an antibody, an antigen binding fragment thereof, an immunoadhesin, a fusion protein, or oligopeptide. Exemplary antibodies are described in U.S. Pat. Nos. 8,735,553, 8,354,509, and 8,008,449, all incorporated herein by reference. Other PD-1 inhibitors for use in the methods and compositions provided herein are known in the art such as described in U.S. Patent Application Nos. US2014/0294898, US2014/022021, and US2011/0008369, all incorporated herein by reference.


In some embodiments, the PD-1 inhibitor is an anti-PD-1 antibody (e.g., a human antibody, a humanized antibody, or a chimeric antibody). In some embodiments, the anti-PD-1 antibody is selected from the group consisting of nivolumab, pembrolizumab, and pidilizumab. In some embodiments, the PD-1 inhibitor is an immunoadhesin (e.g., an immunoadhesin comprising an extracellular or PD-1 binding portion of PDL1 or PDL2 fused to a constant region (e.g., an Fc region of an immunoglobulin sequence). In some embodiments, the PDL1 inhibitor comprises AMP-224. Nivolumab, also known as MDX-1106-04, MDX-1106, ONO-4538, BMS-936558, and OPDIVO®, is an anti-PD-1 antibody described in WO2006/121168. Pembrolizumab, also known as MK-3475, Merck 3475, lambrolizumab, KEYTRUDA®, and SCH-900475, is an anti-PD-1 antibody described in WO2009/114335. Pidilizumab, also known as CT-011, hBAT, or hBAT-1, is an anti-PD-1 antibody described in WO2009/101611. AMP-224, also known as B7-DCIg, is a PDL2-Fc fusion soluble receptor described in WO2010/027827 and WO2011/066342. Additional PD-1 inhibitors include MEDI0680, also known as AMP-514, and REGN2810.


In some embodiments, the immune checkpoint inhibitor is a PDL1 inhibitor such as Durvalumab, also known as MEDI4736, atezolizumab, also known as MPDL3280A, avelumab, also known as MSB00010118C, MDX-1105, BMS-936559, or combinations thereof. In certain aspects, the immune checkpoint inhibitor is a PDL2 inhibitor such as rHIgM12B7.


In some embodiments, the inhibitor comprises the heavy and light chain CDRs or VRs of nivolumab, pembrolizumab, or pidilizumab. Accordingly, in one embodiment, the inhibitor comprises the CDR1, CDR2, and CDR3 domains of the VH region of nivolumab, pembrolizumab, or pidilizumab, and the CDR1, CDR2 and CDR3 domains of the VL region of nivolumab, pembrolizumab, or pidilizumab. In another embodiment, the antibody competes for binding with and/or binds to the same epitope on PD-1. PDL1, or PDL2 as the above-mentioned antibodies. In another embodiment, the antibody has at least about 70, 75, 80, 85, 90, 95, 97, or 99% (or any derivable range therein) variable region amino acid sequence identity with the above-mentioned antibodies.


b. CTLA-4, B7-1, and B7-2


Another immune checkpoint that can be targeted in the methods provided herein is the cytotoxic T-lymphocyte-associated protein 4 (CTLA-4), also known as CD152. The complete cDNA sequence of human CTLA-4 has the Genbank accession number L15006. CTLA-4 is found on the surface of T cells and acts as an “off” switch when bound to B7-1 (CD80) or B7-2 (CD86) on the surface of antigen-presenting cells. CTLA4 is a member of the immunoglobulin superfamily that is expressed on the surface of Helper T cells and transmits an inhibitory signal to T cells. CTLA4 is similar to the T-cell co-stimulatory protein. CD28, and both molecules bind to B7-1 and B7-2 on antigen-presenting cells. CTLA-4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Intracellular CTLA-4 is also found in regulatory T cells and may be important to their function. T cell activation through the T cell receptor and CD28 leads to increased expression of CTLA-4, an inhibitory receptor for B7 molecules. Inhibitors of the disclosure may block one or more functions of CTLA-4, B7-1, and/or B7-2 activity. In some embodiments, the inhibitor blocks the CTLA-4 and B7-1 interaction. In some embodiments, the inhibitor blocks the CTLA-4 and B7-2 interaction.


In some embodiments, the immune checkpoint inhibitor is an anti-CTLA-4 antibody (e.g., a human antibody, a humanized antibody, or a chimeric antibody), an antigen binding fragment thereof, an immunoadhesin, a fusion protein, or oligopeptide.


Anti-human-CTLA-4 antibodies (or VH and/or VL domains derived therefrom) suitable for use in the present methods can be generated using methods well known in the art. Alternatively, art recognized anti-CTLA-4 antibodies can be used. For example, the anti-CTLA-4 antibodies disclosed in: U.S. Pat. No. 8,119,129, WO 01/14424, WO 98/42752; WO 00/37504 (CP675,206, also known as tremelimumab; formerly ticilimumab), U.S. Pat. No. 6,207,156; Hurwitz et al., 1998: can be used in the methods disclosed herein. The teachings of each of the aforementioned publications are hereby incorporated by reference. Antibodies that compete with any of these art-recognized antibodies for binding to CTLA-4 also can be used. For example, a humanized CTLA-4 antibody is described in International Patent Application No. WO2001/014424, WO2000/037504, and U.S. Pat. No. 8,017,114; all incorporated herein by reference.


A further anti-CTLA-4 antibody useful as a checkpoint inhibitor in the methods and compositions of the disclosure is ipilimumab (also known as 10D1, MDX-010, MDX-101, and Yervoy®) or antigen binding fragments and variants thereof (see, e.g., WO0 1/14424).


In some embodiments, the inhibitor comprises the heavy and light chain CDRs or VRs of tremelimumab or ipilimumab. Accordingly, in one embodiment, the inhibitor comprises the CDR1, CDR2, and CDR3 domains of the VH region of tremelimumab or ipilimumab, and the CDR1, CDR2 and CDR3 domains of the VL region of tremelimumab or ipilimumab. In another embodiment, the antibody competes for binding with and/or binds to the same epitope on PD-1. B7-1, or B7-2 as the above-mentioned antibodies. In another embodiment, the antibody has at least about 70, 75, 80, 85, 90, 95, 97, or 99% (or any derivable range therein) variable region amino acid sequence identity with the above-mentioned antibodies.


c. LAG3


Another immune checkpoint that can be targeted in the methods provided herein is the lymphocyte-activation gene 3 (LAG3), also known as CD223 and lymphocyte activating 3. The complete mRNA sequence of human LAG3 has the Genbank accession number NM_002286. LAG3 is a member of the immunoglobulin superfamily that is found on the surface of activated T cells, natural killer cells. B cells, and plasmacytoid dendritic cells. LAG3's main ligand is MHC class II, and it negatively regulates cellular proliferation, activation, and homeostasis of T cells, in a similar fashion to CTLA-4 and PD-1, and has been reported to play a role in Treg suppressive function. LAG3 also helps maintain CD8+ T cells in a tolerogenic state and, working with PD-1, helps maintain CD8 exhaustion during chronic viral infection. LAG3 is also known to be involved in the maturation and activation of dendritic cells. Inhibitors of the disclosure may block one or more functions of LAG3 activity.


In some embodiments, the immune checkpoint inhibitor is an anti-LAG3 antibody (e.g., a human antibody, a humanized antibody, or a chimeric antibody), an antigen binding fragment thereof, an immunoadhesin, a fusion protein, or oligopeptide.


Anti-human-LAG3 antibodies (or VH and/or VL domains derived therefrom) suitable for use in the present methods can be generated using methods well known in the art. Alternatively, art recognized anti-LAG3 antibodies can be used. For example, the anti-LAG3 antibodies can include: GSK2837781, IMP321, FS-118, Sym022, TSR-033, MGD013, BI754111, AVA-017, or GSK2831781. The anti-LAG3 antibodies disclosed in: U.S. Pat. No. 9,505,839 (BMS-986016, also known as relatlimab); U.S. Pat. No. 10,711,060 (IMP-701, also known as LAG525); U.S. Pat. No. 9,244,059 (IMP731, also known as H5L7BW); U.S. Pat. No. 10,344,089 (25F7, also known as LAG3.1); WO 2016/028672 (MK-4280, also known as 28G-10); WO 2017/019894 (BAP050); Burova E., et al., J. ImmunoTherapy Cancer, 2016; 4(Supp. 1):P195 (REGN3767); Yu. X., et al., mAbs, 2019: 11:6 (LBL-007) can be used in the methods disclosed herein. These and other anti-LAG-3 antibodies useful in the claimed invention can be found in, for example: WO 2016/028672, WO 2017/106129, WO 2017062888, WO 2009/044273, WO 2018/069500, WO 2016/126858, WO 2014/179664, WO 2016/200782, WO 2015/200119, WO 2017/019846, WO 2017/198741, WO 2017/220555, WO 2017/220569, WO 2018/071500, WO 2017/015560; WO 2017/025498, WO 2017/087589, WO 2017/087901, WO 2018/083087, WO 2017/149143, WO 2017/219995, US 2017/0260271, WO 2017/086367, WO 2017/086419, WO 2018/034227, and WO 2014/140180. The teachings of each of the aforementioned publications are hereby incorporated by reference. Antibodies that compete with any of these art-recognized antibodies for binding to LAG3 also can be used.


In some embodiments, the inhibitor comprises the heavy and light chain CDRs or VRs of an anti-LAG3 antibody. Accordingly, in one embodiment, the inhibitor comprises the CDR1, CDR2, and CDR3 domains of the VH region of an anti-LAG3 antibody, and the CDR1, CDR2 and CDR3 domains of the VL region of an anti-LAG3 antibody. In another embodiment, the antibody has at least about 70, 75, 80, 85, 90, 95, 97, or 99% (or any derivable range therein) variable region amino acid sequence identity with the above-mentioned antibodies.


d. TIM-3


Another immune checkpoint that can be targeted in the methods provided herein is the T-cell immunoglobulin and mucin-domain containing-3 (TIM-3), also known as hepatitis A virus cellular receptor 2 (HAVCR2) and CD366. The complete mRNA sequence of human TIM-3 has the Genbank accession number NM_032782. TIM-3 is found on the surface IFNγ-producing CD4+Th1 and CD8+Tc1 cells. The extracellular region of TIM-3 consists of a membrane distal single variable immunoglobulin domain (IgV) and a glycosylated mucin domain of variable length located closer to the membrane. TIM-3 is an immune checkpoint and, together with other inhibitory receptors including PD-1 and LAG3, it mediates the T-cell exhaustion. TIM-3 has also been shown as a CD4+Th1-specific cell surface protein that regulates macrophage activation. Inhibitors of the disclosure may block one or more functions of TIM-3 activity.


In some embodiments, the immune checkpoint inhibitor is an anti-TIM-3 antibody (e.g., a human antibody, a humanized antibody, or a chimeric antibody), an antigen binding fragment thereof, an immunoadhesin, a fusion protein, or oligopeptide.


Anti-human-TIM-3 antibodies (or VH and/or VL domains derived therefrom) suitable for use in the present methods can be generated using methods well known in the art. Alternatively, art recognized anti-TIM-3 antibodies can be used. For example, anti-TIM-3 antibodies including: MBG453, TSR-022 (also known as Cobolimab), and LY3321367 can be used in the methods disclosed herein. These and other anti-TIM-3 antibodies useful in the claimed invention can be found in, for example: U.S. Pat. Nos. 9,605,070, 8,841,418, US2015/0218274, and US 2016/0200815. The teachings of each of the aforementioned publications are hereby incorporated by reference. Antibodies that compete with any of these art-recognized antibodies for binding to TIM-3 also can be used.


In some embodiments, the inhibitor comprises the heavy and light chain CDRs or VRs of an anti-TIM-3 antibody. Accordingly, in one embodiment, the inhibitor comprises the CDR1. CDR2, and CDR3 domains of the VH region of an anti-TIM-3 antibody, and the CDR1, CDR2 and CDR3 domains of the VL region of an anti-TIM-3 antibody. In another embodiment, the antibody has at least about 70, 75, 80, 85, 90, 95, 97, or 99% (or any derivable range or value therein) variable region amino acid sequence identity with the above-mentioned antibodies.


2. Activation of Co-Stimulatory Molecules


In some embodiments, the immunotherapy comprises an activator of a co-stimulatory molecule. In some embodiments, the activator comprises an agonist of B7-1 (CD80), B7-2 (CD86), CD28, ICOS, OX40 (TNFRSF4), 4-1BB (CD137: TNFRSF9), CD40L (CD40LG), GITR (TNFRSF18), and combinations thereof. Activators include agonistic antibodies, polypeptides, compounds, and nucleic acids.


3. Dendritic Cell Therapy


Dendritic cell therapy provokes anti-tumor responses by causing dendritic cells to present tumor antigens to lymphocytes, which activates them, priming them to kill other cells that present the antigen. Dendritic cells are antigen presenting cells (APCs) in the mammalian immune system. In cancer treatment they aid cancer antigen targeting. One example of cellular cancer therapy based on dendritic cells is sipuleucel-T.


One method of inducing dendritic cells to present tumor antigens is by vaccination with autologous tumor lysates or short peptides (small parts of protein that correspond to the protein antigens on cancer cells). These peptides are often given in combination with adjuvants (highly immunogenic substances) to increase the immune and anti-tumor responses. Other adjuvants include proteins or other chemicals that attract and/or activate dendritic cells, such as granulocyte macrophage colony-stimulating factor (GM-CSF).


Dendritic cells can also be activated in vivo by making tumor cells express GM-CSF. This can be achieved by either genetically engineering tumor cells to produce GM-CSF or by infecting tumor cells with an oncolytic virus that expresses GM-CSF.


Another strategy is to remove dendritic cells from the blood of a patient and activate them outside the body. The dendritic cells are activated in the presence of tumor antigens, which may be a single tumor-specific peptide/protein or a tumor cell lysate (a solution of broken down tumor cells). These cells (with optional adjuvants) are infused and provoke an immune response.


Dendritic cell therapies include the use of antibodies that bind to receptors on the surface of dendritic cells. Antigens can be added to the antibody and can induce the dendritic cells to mature and provide immunity to the tumor. Dendritic cell receptors such as TLR3, TLR7, TLR8 or CD40 have been used as antibody targets.


4. CAR-T Cell Therapy


Chimeric antigen receptors (CARs, also known as chimeric immunoreceptors, chimeric T cell receptors or artificial T cell receptors) are engineered receptors that combine a new specificity with an immune cell to target cancer cells. Typically, these receptors graft the specificity of a monoclonal antibody onto a T cell, NK cell, or other immune cell. The receptors are called chimeric because they are fused of parts from different sources. CAR-T cell therapy refers to a treatment that uses such transformed T-cells for cancer therapy. Similarly, CAR-NK cell therapy refers to a treatment that uses such transformed NK cells for cancer therapy.


The basic principle of CAR-T cell design involves recombinant receptors that combine antigen-binding and T-cell activating functions. The general premise of CAR-T cells is to artificially generate T-cells targeted to markers found on cancer cells. Scientists can remove T-cells from a person, genetically alter them, and put them back into the patient for them to attack the cancer cells. Once the T cell has been engineered to become a CAR-T cell, it acts as a “living drug”. CAR-T cells create a link between an extracellular ligand recognition domain to an intracellular signalling molecule which in turn activates T cells. The extracellular ligand recognition domain is usually a single-chain variable fragment (scFv). An important aspect of the safety of CAR-T cell therapy is how to ensure that only cancerous tumor cells are targeted, and not normal cells. The specificity of CAR-T cells is determined by the choice of molecule that is targeted.


Exemplary CAR-T therapies include Tisagenlecleucel (Kymriah) and Axicabtagene ciloleucel (Yescarta). In some embodiments, the CAR-T therapy targets CD19.


5. Cytokine Therapy


Cytokines are proteins produced by many types of cells present within a tumor. They can modulate immune responses. The tumor often employs them to allow it to grow and reduce the immune response. These immune-modulating effects allow them to be used as drugs to provoke an immune response. Two commonly used cytokines are interferons and interleukins.


Interferons are produced by the immune system. They are usually involved in anti-viral response, but also have use for cancer. They fail in three groups: type I (IFNα and IFNβ), type II (IFNγ) and type III (IFNλ).


Interleukins have an array of immune system effects. IL-2 is an exemplary interleukin cytokine therapy.


6. Adoptive T-cell therapy


Adoptive T cell therapy is a form of passive immunization by the transfusion of T-cells (adoptive cell transfer). They are found in blood and tissue and usually activate when they find foreign pathogens. Specifically they activate when the T-cell's surface receptors encounter cells that display parts of foreign proteins on their surface antigens. These can be either infected cells, or antigen presenting cells (APCs). They are found in normal tissue and in tumor tissue, where they are known as tumor infiltrating lymphocytes (TILs). They are activated by the presence of APCs such as dendritic cells that present tumor antigens. Although these cells can attack the tumor, the environment within the tumor is highly immunosuppressive, preventing immune-mediated tumour death.


Multiple ways of producing and obtaining tumour targeted T-cells have been developed. T-cells specific to a tumor antigen can be removed from a tumor sample (TILs) or filtered from blood. Subsequent activation and culturing is performed ex vivo, with the results reinfused. Activation can take place through gene therapy, or by exposing the T cells to tumor antigens.


It is contemplated that a cancer treatment may exclude any of the cancer treatments described herein. Furthermore, embodiments of the disclosure include patients that have been previously treated for a therapy described herein, are currently being treated for a therapy described herein, or have not been treated for a therapy described herein. In some embodiments, the patient is one that has been determined to be resistant to a therapy described herein. In some embodiments, the patient is one that has been determined to be sensitive to a therapy described herein. VII. Administration of Therapeutic Combinations


The therapy provided herein may comprise administration of a combination of therapeutic agents, such as a first cancer therapy and a second cancer therapy. The therapies may be administered in any suitable manner known in the art. For example, the first and second cancer treatment may be administered sequentially (at different times) or concurrently (at the same time). In some embodiments, the first and second cancer treatments are administered in a separate composition. In some embodiments, the first and second cancer treatments are in the same composition.


Embodiments of the disclosure relate to compositions and methods comprising therapeutic compositions. Different therapies may be administered in one composition or in more than one composition, such as 2 compositions, 3 compositions, or 4 compositions. Various combinations of the agents may be employed.


Therapeutic agents of the disclosure may be administered by the same route of administration or by different routes of administration. In some embodiments, the cancer therapy is administered intravenously, intramuscularly, subcutaneously, topically, orally, transdermally, intraperitoneally, intraorbitally, by implantation, by inhalation, intrathecally, intraventricularly, or intranasally. The appropriate dosage may be determined based on the type of disease to be treated, severity and course of the disease, the clinical condition of the individual, the individual's clinical history and response to the treatment, and the discretion of the attending physician.


The treatments may include various “unit doses.” Unit dose is defined as containing a predetermined-quantity of the therapeutic composition. The quantity to be administered, and the particular route and formulation, is within the skill of determination of those in the clinical arts. A unit dose need not be administered as a single injection but may comprise continuous infusion over a set period of time. In some embodiments, a unit dose comprises a single administrable dose.


The quantity to be administered, both according to number of treatments and unit dose, depends on the treatment effect desired. An effective dose is understood to refer to an amount necessary to achieve a particular effect. In the practice in certain embodiments, it is contemplated that doses in the range from 10 mg/kg to 200 mg/kg can affect the protective capability of these agents. Thus, it is contemplated that doses include doses of about 0.1, 0.5, 1, 5, 10, 15, 20, 25, 30, 35, 40, 45, 50, 55, 60, 65, 70, 75, 80, 85, 90, 100, 105, 110, 115, 120, 125, 130, 135, 140, 145, 150, 155, 160, 165, 170, 175, 180, 185, 190, 195, and 200, 300, 400, 500, 1000 μg/kg, mg/kg, μg/day, or mg/day or any range derivable therein. Furthermore, such doses can be administered at multiple times during a day, and/or on multiple days, weeks, or months.


In certain embodiments, the effective dose of the pharmaceutical composition is one which can provide a blood level of about 1 μM to 150 μM. In another embodiment, the effective dose provides a blood level of about 4 μM to 100 μM; or about 1 μM to 100 μM; or about 1 μM to 50 μM; or about 1 μM to 40 μM; or about 1 μM to 30 μM; or about 1 μM to 20 μM; or about 1 μM to 10 μM; or about 10 μM to 150 μM; or about 10 μM to 100 μM; or about 10 μM to 50 μM; or about 25 μM to 150 μM; or about 25 μM to 100 μM; or about 25 μM to 50 μM; or about 50 μM to 150 μM; or about 50 μM to 100 μM (or any range derivable therein). In other embodiments, the dose can provide the following blood level of the agent that results from a therapeutic agent being administered to a subject: about, at least about, or at most about 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, or 100 μM or any range derivable therein. In certain embodiments, the therapeutic agent that is administered to a subject is metabolized in the body to a metabolized therapeutic agent, in which case the blood levels may refer to the amount of that agent. Alternatively, to the extent the therapeutic agent is not metabolized by a subject, the blood levels discussed herein may refer to the unmetabolized therapeutic agent.


Precise amounts of the therapeutic composition also depend on the judgment of the practitioner and are peculiar to each individual. Factors affecting dose include physical and clinical state of the patient, the route of administration, the intended goal of treatment (alleviation of symptoms versus cure) and the potency, stability and toxicity of the particular therapeutic substance or other therapies a subject may be undergoing.


It will be understood by those skilled in the art and made aware that dosage units of μg/kg or mg/kg of body weight can be converted and expressed in comparable concentration units of μg/ml or mM (blood levels), such as 4 μM to 100 μM. It is also understood that uptake is species and organ/tissue dependent. The applicable conversion factors and physiological assumptions to be made concerning uptake and concentration measurement are well-known and would permit those of skill in the art to convert one concentration measurement to another and make reasonable comparisons and conclusions regarding the doses, efficacies and results described herein.


VIII. Kits

Certain aspects of the present disclosure also concern kits containing compositions of the disclosure or compositions to implement methods disclosed herein. In some embodiments, kits can be used to evaluate one or more biomarkers, such as methylation levels. In certain embodiments, a kit contains, contains at least or contains at most 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 100, 500, 1,000 or more probes, primers or primer sets, synthetic molecules or inhibitors, or any value or range and combination derivable therein. In some embodiments, there are kits for evaluating methylation levels of tumor DNA.


Kits may comprise components, which may be individually packaged or placed in a container, such as a tube, bottle, vial, syringe, or other suitable container means.


Individual components may also be provided in a kit in concentrated amounts: in some embodiments, a component is provided individually in the same concentration as it would be in a solution with other components. Concentrations of components may be provided as 1×, 2×, 5×, 10×, or 20× or more.


Kits for using probes, synthetic nucleic acids, nonsynthetic nucleic acids, and/or inhibitors of the disclosure for prognostic or diagnostic applications are included as part of the disclosure. Specifically contemplated are any such molecules corresponding to any biomarker identified herein, which includes nucleic acid primers/primer sets and probes that are identical to or complementary to all or part of a biomarker, which may include noncoding sequences of the biomarker, as well as coding sequences of the biomarker.


In certain aspects, negative and/or positive control nucleic acids, probes, and inhibitors are included in some kit embodiments. In addition, a kit may include a sample that is a negative or positive control for methylation of one or more biomarkers. In some embodiments, a control includes a nucleic acid that contains at least one CpG or is capable of identifying a CpG methylation site.


Any embodiment of the disclosure involving specific biomarker by name is contemplated also to cover embodiments involving biomarkers whose sequences are at least 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99% identical to the mature sequence of the specified nucleic acid.


Embodiments of the disclosure include kits for analysis of a pathological sample by assessing biomarker profile for a sample comprising, in suitable container means, two or more biomarker probes, wherein the biomarker probes detect one or more of the biomarkers identified herein. The kit can further comprise reagents for labeling nucleic acids in the sample. The kit may also include labeling reagents, including at least one of amine-modified nucleotide, poly(A) polymerase, and poly(A) polymerase buffer. Labeling reagents can include an amine-reactive dye.


It is contemplated that any method or composition described herein can be implemented with respect to any other method or composition described herein and that different embodiments may be combined. The claims originally filed are contemplated to cover claims that are multiply dependent on any filed claim or combination of filed claims.


EXAMPLES

The following examples are included to demonstrate certain embodiments of the invention. It should be appreciated by those of skill in the art that the techniques disclosed in the examples which follow represent techniques discovered by the inventor to function well in the practice of the invention. However, those of skill in the art should, in light of the present disclosure, appreciate that many changes can be made in the specific embodiments which are disclosed and still obtain a like or similar result without departing from the spirit and scope of the invention.


Example 1—Classification of SCLC Based on Methylation Markers Derived from Cell Lines

For the identification of distinct methylation sites, two published datasets were used, derived from the GDSC project (described in Iorio et al., Cell. 2016 Jul. 28; 166(3):740-754. doi: 10.1016/j.cell.2016.06.017, incorporated herein by reference in its entirety) and the NCI DTP SCLC project (available from the World Wide Web at sclccelflines.cancer.gov/sclc/). Association of methylation sites with SCLC subtype was assessed using Area Under the Receiver Operating Characteristics (AUROC) and the top 15,000 Methylation sites were used for further analysis. The general feasibility of using methylation to distinguish SCLC-subtypes is highlighted in FIGS. 1A-1B.


The clustering in FIGS. 1A-1B revealed that the top 1000 methylation sites were indeed able to distinguish the different subtypes, however clustering separated the subtypes less in the NCI dataset (FIG. 1B) than in the GDSC dataset (FIG. 1A). Consequently, a machine learning based algorithm was used to improve classification of the subtypes. Those models were validated only for the SCLC-A and SCLC-N subtype across the two datasets as there was limited data present for the SCLC-P and the SCLC-I dataset. However, several markers with an AUROC=1 have been identified in the latter two subsets highlighting their validity to distinguish the subsets.


Importantly, the models demonstrated an impressive prediction for distinguishing the SCLC-A (FIG. 2A) and the SCLC-N subtypes (FIG. 2B). Interestingly, models generated using net-elastic logistic regression outperformed the models built using the random forest approach. Importantly, those results clearly highlight that methylation-based markers can be used for the classification of SCLC subtypes.


The differentiation of the respective subsets using a large number of methylation markers was demonstrated; however, the inventors hypothesized that a comparable prediction of the SCLC subset was also possible with a dramatically reduced set of methylation sites using only 2 instead of 15,000 methylation sites per subtype. Therefore, the most promising methylation sites (top 20 sites based on ROC analysis) were selected and all possible combinations of two markers were tested to assess if this approach was feasible to reduce the marker set.


Importantly, as highlighted in FIG. 3 for the SCLC-A models and FIG. 4 for SCLC-N models, the approach of reducing the marker set to only two per subtypes was very successful in the SCLC-A and SCLC-N subtypes demonstrating that a reduced marker set was indeed capable of distinguishing the subtypes with comparable predictive performance. The top ten two-gene combinations for the SCLC-A and SCLC-N subtypes are provided in Tables 11 and 12.


The models were initially exclusively trained on cell line samples and thus it was important to confirm how well they generalized over real tumor samples. Additionally, was is important to assess how the models compare on other tumor samples. Prediction on tumor samples was performed with coexisting gene expression data using the GSE56044 dataset. Prediction of subtypes was done using the models trained on the cell line data, which had never seen original tumor data. Results are highlighted in FIG. 5.


As seen in FIG. 5, the created models indeed generalized very well and were able to classify both SCLC and other HGNEC, such as LCNEC/LC. The results of the subgroups were concordant with the expression of the underlying markers highlighting the good reliability. Importantly, non-SCLC/LCNEC tumors showed no signal highlighting a certain specificity for SCLC/LCNEC.


Importantly, the models were trained using 15,000 methylation markers per subtype. To analyze whether the reduction to 2-3 markers was feasible, the inventors generated models using only the reduced marker-set by assessing all combinations of the top markers that were selected for further analysis in plasma (Table 6). The results are highlighted in FIG. 6 (SCLC-A), FIG. 7 (SCLC-N), FIG. 8 (SCLC-P), and FIG. 9 (SCLC-I). Importantly, the reduced models using only 2-3 markers aligned well with the expression of the markers and showed concordant results with the larger models incorporating 15.000 methylation sites. This clearly demonstrated that reducing the markers was a feasible approach.


All methylation sites were assessed for their suitability in a liquid biopsy assay. Therefore, several resources comprising of DNA methylation from blood samples (GSE15018, GSE42861, GSE123914) and from various tissue including ctDNA (cfDNA Atlas Project). Methylation sites with a large difference from background methylation (defined by the various sources) were defined to be suitable in a liquid biopsy assay. Some examples are given in FIG. 10. Methylation sites suitable for analysis using a liquid biopsy assay are shown in Tables 6, 7, 8, 9, and 10.









TABLE 1







Top 1000 methylation sites associated with each of the SCLC-A, -N, -P, and -I subtypes













Methylation
Position

Associated


Relation to


Site
(GRCh 37)
Gene
Subgroup
Strand
CpG Island Name
CpG Island





cg20728514
chr22: 44568423
PARVG.TSS1500
SCLC-A
R




cg13429423
chr22: 44568775
PARVG.TSS200
SCLC-A
F


cg04506569
chr2: 234837977
TRPM8.GENEBODY
SCLC-A
F


cg17542751
chr22: 44568725
PARVG.TSS200
SCLC-A
R


cg12688942
chr1: 19680353
CAPZB.GENEBODY
SCLC-A
R


cg25353896
chr22: 44568753
PARVG.TSS200
SCLC-A
F


cg02911509
chr22: 44568770
PARVG.TSS200
SCLC-A
F


cg16873414
chr22: 44568699
PARVG.TSS200
SCLC-A
R


cg25901559
chr7: 157585255
PTPRN2.GENEBODY
SCLC-A
F
chr7: 157586711-
N_Shore







157587112


cg07639982
chr10: 12555079
CAMK1D.GENEBODY
SCLC-A
F


cg08271031
chr22: 44568812
PARVG.TSS200
SCLC-A
R


cg17622855
chr6: 157982358
ZDHHC14.GENEBODY
SCLC-A
R


cg03817675
chr7: 139299053
HIPK2.GENEBODY
SCLC-A
R


cg17252884
chr3: 15369681
SH3BP5.GENEBODY
SCLC-A
F
chr3: 15373314-
N_Shelf







15374209


cg07213482
chr4: 89660237
FAM13A.GENEBODY
SCLC-A
R


cg12907969
chr5: 89815060
LYSMD3.GENEBODY
SCLC-A
R


cg25694807
chr2: 161329607
RBMS1.GENEBODY
SCLC-A
F


cg00090674
chr22: 50446678
IL17REL.UTR5
SCLC-A
F
chr22: 50448567-
N_Shore







50449521


cg23317857
chr6: 41696297
TFEB.UTR5
SCLC-A
F


cg11201256
chr1: 184403226
C1orf21.UTR5
SCLC-A
R


cg16860004
chr8: 103137229
NCALD.TSS1500
SCLC-A
F
chr8: 103135914-
S_Shore







103136775


cg15892280
chr21: 40180000
ETS2.UTR5
SCLC-A
F
chr21: 40177002-
S_Shore







40178667


cg03568507
chr2: 240153791
HDAC4.GENEBODY
SCLC-A
F
chr2: 240153476-
Island







240153792


cg19437757
chr7: 157697057
PTPRN2.GENEBODY
SCLC-A
R
chr7: 157695025-
S_Shore







157695358


cg27550325
chr7: 157915584
PTPRN2.GENEBODY
SCLC-A
R
chr7: 157918704-
N_Shelf







157919409


cg27122614
chr7: 157913741
PTPRN2.GENEBODY
SCLC-A
R


cg27110054
chr8: 103137274
NCALD.TSS1500
SCLC-A
R
chr8: 103135914-
S_Shore







103136775


cg07572930
chr16: 81527107
CMIP.GENEBODY
SCLC-A
F


cg17479501
chr17: 80806191
TBCD.GENEBODY
SCLC-A
R


cg02161503
chr7: 157955692
PTPRN2.GENEBODY
SCLC-A
R
chr7: 157956911-
N_Shore







157957273


cg13287553
chr7: 4784419
FOXK1.GENEBODY
SCLC-A
F
chr7: 4784820-4785058
N_Shore


cg25746499
chr2: 240153778
HDAC4.GENEBODY
SCLC-A
F
chr2: 240153476-
Island







240153792


cg10672201
chr12: 103353320
ASCL1.UTR3
SCLC-A
F
chr12: 103351579-
S_Shore







103352695


cg06043710
chr10: 560371
DIP2C.GENEBODY
SCLC-A
F


cg18966819
chr7: 4784325
FOXK1.GENEBODY
SCLC-A
R
chr7: 4784820-4785058
N_Shore


cg18578954
chr6: 28887247
TRIM27.GENEBODY
SCLC-A
F
chr6: 28890951-
N_Shelf







28892013


cg06228260
chr7: 157854729
PTPRN2.GENEBODY
SCLC-A
R


cg03899215
chr7: 157996423
PTPRN2.GENEBODY
SCLC-A
R
chr7: 157996642-
N_Shore







157997027


cg08946713
chr2: 191844998
STAT1.GENEBODY
SCLC-A
F


cg18424850
chr10: 132945786
TCERG1L.GENEBODY
SCLC-A
R


cg21167502
chr14: 104195666
ZFYVE21.GENEBODY
SCLC-A
R
chr14: 104193901-
S_Shore







104194627


cg27119612
chr15: 57491001
TCF12.GENEBODY
SCLC-A
R


cg04921578
chr13: 101143257
PCCA.GENEBODY
SCLC-A
F


cg08277369
chr16: 84538885
KIAA1609.TSS1500
SCLC-A
F
chr16: 84538884-
Island







84539115


cg08448341
chr6: 134324873
SLC2A12.GENEBODY
SCLC-A
F


cg15193475
chr15: 80998711
FAM108C1.GENEBODY
SCLC-A
F


cg17468616
chr1: 226013212
EPHX1.EXON1
SCLC-A
F


cg18730511
chr22: 50435413
IL17REL.UTR3
SCLC-A
F
chr22: 50438257-
N_Shelf







50438776


cg26239495
chr11: 122791447
C11orf63.GENEBODY
SCLC-A
R


cg01441025
chr8: 103136942
NCALD.EXON1
SCLC-A
F
chr8: 103135914-
S_Shore







103136775


cg15577272
chr7: 157932397
PTPRN2.GENEBODY
SCLC-A
F


cg21373996
chr10: 560669
DIP2C.GENEBODY
SCLC-A
R


cg06650067
chr15: 66084924
DENND4A.TSS1500
SCLC-A
R
chr15: 66083839-
Island







66084925


cg08951403
chr7: 157960420
PTPRN2.GENEBODY
SCLC-A
F
chr7: 157956911-
S_Shelf







157957273


cg09500207
chr11: 68249304
SAPS3.UTR5
SCLC-A
R


cg16896647
chr9: 93563776
SYK.TSS1500
SCLC-A
R
chr9: 93563775-
Island







93564546


cg10227678
chr16: 54096340
FTO.GENEBODY
SCLC-A
F


cg18883682
chr7: 36655667
AOAH.GENEBODY
SCLC-A
R


cg03558805
chr7: 73184883
CLDN3.TSS1500
SCLC-A
F
chr7: 73183379-
Island







73185115


cg03856153
chr3: 61904580
PTPRG.GENEBODY
SCLC-A
R


cg04610718
chr12: 103353362
ASCL1.UTR3
SCLC-A
F
chr12: 103351579-
S_Shore







103352695


cg06946543
chr13: 76377366
LMO7.UTR5
SCLC-A
F


cg09845489
chr7: 157667853
PTPRN2.GENEBODY
SCLC-A
R
chr7: 157666069-
S_Shore







157666399


cg10919624
chr7: 158279891
PTPRN2.GENEBODY
SCLC-A
F
chr7: 158281373-
N_Shore







158281734


cg00799539
chr12: 103353183
ASCL1.UTR3
SCLC-A
R
chr12: 103351579-
S_Shore







103352695


cg06663149
chr4: 41457558
LIMCH1.GENEBODY
SCLC-A
F


cg13656878
chr9: 119048807
PAPPA.GENEBODY
SCLC-A
F


cg14207833
chr19: 18945153
UPF1.GENEBODY
SCLC-A
F
chr19: 18942432-
S_Shelf







18943127


cg16762386
chr1: 27240514
NROB2.EXON1
SCLC-A
F


cg26350286
chr8: 95652691
ESRP1.TSS1500
SCLC-A
R
chr8: 95652455-
Island







95652873


cg00624799
chr15: 90605618
ZNF710.UTR5
SCLC-A
R


cg03519907
chr5: 154092426
LARP1.TSS200
SCLC-A
F


cg09176199
chr1: 246383021
SMYD3.GENEBODY
SCLC-A
F


cg15192120
chr7: 157626176
PTPRN2.GENEBODY
SCLC-A
R


cg16048383
chr12: 6483708
SCNN1A.GENEBODY
SCLC-A
R


cg22550299
chr6: 169654842
THBS2.TSS1500
SCLC-A
R


cg23936766
chr1: 230406371
GALNT2.GENEBODY
SCLC-A
R


cg02390801
chr15: 74528565
CCDC33.TSS200
SCLC-A
F


cg05503433
chr19: 42409117
ARHGEF1.GENEBODY
SCLC-A
F
chr19: 42408315-
S_Shore







42408535


cg09259081
chr16: 84538889
KIAA1609.TSS1500
SCLC-A
F
chr16: 84538884-
Island







84539115


cg13547053
chr2: 179184864
OSBPL6.TSS200
SCLC-A
R


cg25037165
chr11: 12824283
TEAD1.GENEBODY
SCLC-A
R


cg01187496
chr5: 167718124
WWC1.TSS1500
SCLC-A
F
chr5: 167718523-
N_Shore







167719688


cg06338523
chr7: 158279818
PTPRN2.GENEBODY
SCLC-A
F
chr7: 158281373-
N_Shore







158281734


cg14947787
chr14: 65405931
GPX2.UTR3
SCLC-A
F


cg16311186
chr7: 140114137
RAB19.GENEBODY
SCLC-A
F


cg17176609
chr2: 74135217
ACTG2.GENEBODY
SCLC-A
R


cg19648306
chr2: 179184854
OSBPL6.TSS200
SCLC-A
R


cg19747960
chr8: 11269117
C8orf12.GENEBODY
SCLC-A
R


cg21867891
chr18: 56529835
ZNF532.TSS1500
SCLC-A
R
chr18: 56530395-
N_Shore







56531288


cg07124138
chr16: 88683903
ZC3H18.GENEBODY
SCLC-A
R


cg27336068
chr10: 1336103
ADARB2.GENEBODY
SCLC-A
R


cg19954227
chr7: 158113303
PTPRN2.GENEBODY
SCLC-A
F
chr7: 158109334-
S_Shelf







158109594


cg20802509
chr1: 229764652
URB2.GENEBODY
SCLC-A
F
chr1: 229761128-
S_Shelf







229762299


cg21679730
chr1: 65047485
CACHD1.GENEBODY
SCLC-A
R


cg21732383
chr6: 169654692
THBS2.TSS1500
SCLC-A
F


cg02428178
chr15: 49104237
CEP152.TSS1500
SCLC-A
R
chr15: 49102731-
S_Shore







49102938


cg09450352
chr7: 157495481
PTPRN2.GENEBODY
SCLC-A
R
chr7: 157494510-
S_Shore







157494739


cg13579752
chr5: 153577937
GALNT10.GENEBODY
SCLC-A
F


cg14647989
chr22: 43824766
MPPED1.GENEBODY
SCLC-A
R
chr22: 43820887-
S_Shelf







43821136


cg14667175
chr2: 111623300
ACOXL.GENEBODY
SCLC-A
F


cg19212465
chr7: 157654170
PTPRN2.GENEBODY
SCLC-A
F


cg25029446
chr7: 157495282
PTPRN2.GENEBODY
SCLC-A
F
chr7: 157494510-
S_Shore







157494739


cg00064840
chr7: 4784485
FOXK1.GENEBODY
SCLC-A
F
chr7: 4784820-4785058
N_Shore


cg02473460
chr8: 93074521
RUNX1T1.GENEBODY
SCLC-A
R


cg10880973
chr6: 157982213
ZDHHC14.GENEBODY
SCLC-A
R


cg15046304
chr17: 75205489
SEC14L1.GENEBODY
SCLC-A
F
chr17: 75209459-
N_Shelf







75209672


cg22598247
chr7: 157614399
PTPRN2.GENEBODY
SCLC-A
R
chr7: 157612036-
S_Shelf







157612316


cg26247373
chr12: 57655696
R3HDM2.GENEBODY
SCLC-A
F


cg00911446
chr1: 7520079
CAMTA1.GENEBODY
SCLC-A
F


cg12761282
chr20: 2276571
TGM3.TSS200
SCLC-A
R


cg16645907
chr5: 154092360
LARP1.TSS200
SCLC-A
F


cg22057874
chr2: 179184866
OSBPL6.TSS200
SCLC-A
R


cg24928687
chr1: 226012913
EPHX1.TSS200
SCLC-A
R


cg00668890
chr12: 6449990
TNFRSF1A.GENEBODY
SCLC-A
R


cg02901644
chr2: 234369787
DGKD.GENEBODY
SCLC-A
R
chr2: 234369786-
Island







234370099


cg07696006
chr15: 74528563
CCDC33.TSS200
SCLC-A
F


cg11575295
chr7: 158250911
PTPRN2.GENEBODY
SCLC-A
F
chr7: 158247888-
S_Shore







158249312


cg15228639
chr15: 42289939
PLA2G4E.GENEBODY
SCLC-A
R


cg24241530
chr7: 158061820
PTPRN2.GENEBODY
SCLC-A
R
chr7: 158060894-
S_Shore







158061100


cg27555529
chr19: 13617518
CACNA1A.TSS1500
SCLC-A
F
chr19: 13616752-
S_Shore







13617267


cg08758185
chr5: 150849936
SLC36A1.GENEBODY
SCLC-A
F


cg10899175
chr2: 11680144
GREB1.EXON1
SCLC-A
F


cg15298059
chr7: 157668141
PTPRN2.GENEBODY
SCLC-A
F
chr7: 157669879-
N_Shore







157670095


cg18635670
chr6: 26539327
HMGN4.UTR5
SCLC-A
R
chr6: 26538496-
S_Shore







26539015


cg20149780
chr1: 15751063
EFHD2.GENEBODY
SCLC-A
F


cg03877767
chr2: 11680057
GREB1.UTR5
SCLC-A
F


cg10126234
chr14: 104195533
ZFYVE21.GENEBODY
SCLC-A
R
chr14: 104193901-
S_Shore







104194627


cg11035519
chr11: 130051458
ST14.GENEBODY
SCLC-A
F


cg11281961
chr2: 97498902
CNNM3.UTR3
SCLC-A
R


cg12098949
chr17: 75367442
SEPT9.UTR5
SCLC-A
F
chr17: 75368688-
N_Shore







75370506


cg18738906
chr12: 6483739
SCNN1A.GENEBODY
SCLC-A
R


cg24034277
chr14: 102467421
DYNC1H1.GENEBODY
SCLC-A
F


cg25264630
chr7: 157849744
PTPRN2.GENEBODY
SCLC-A
F


cg26849830
chr12: 109178373
SSH1.UTR3
SCLC-A
R


cg06221087
chr1: 164659666
PBX1.GENEBODY
SCLC-A
F


cg06694040
chr11: 11301699
GALNTL4.GENEBODY
SCLC-A
F


cg07875069
chr7: 129985025
CPA5.EXON1
SCLC-A
R


cg19308132
chr8: 103137173
NCALD.TSS1500
SCLC-A
F
chr8: 103135914-
S_Shore







103136775


cg19897017
chr7: 2163380
MAD1L1.GENEBODY
SCLC-A
F


cg27655671
chr6: 38207741
BTBD9.GENEBODY
SCLC-A
F


cg05800761
chr18: 56529852
ZNF532.TSS1500
SCLC-A
F
chr18: 56530395-
N_Shore







56531288


cg20371765
chr7: 8302271
ICA1.TSS200
SCLC-A
F
chr7: 8301031-8302252
S_Shore


cg02716952
chr7: 148504681
EZH2.UTR3
SCLC-A
R


cg14592260
chr11: 108798655
DDX10.GENEBODY
SCLC-A
F


cg16937735
chr7: 157562675
PTPRN2.GENEBODY
SCLC-A
R
chr7: 157560974-
S_Shore







157561195


cg17208060
chr2: 11680086
GREB1.EXON1
SCLC-A
R


cg22968401
chr17: 27370009
PIPOX.UTR5
SCLC-A
F


cg23884690
chr13: 113678926
MCF2L.GENEBODY
SCLC-A
R
chr13: 113676781-
S_Shore







113677120


cg27431545
chr2: 173607996
RAPGEF4.GENEBODY
SCLC-A
F


cg00283887
chr7: 157935557
PTPRN2.GENEBODY
SCLC-A
F
chr7: 157937614-
N_Shelf







157937841


cg00773370
chr12: 6483772
SCNN1A.GENEBODY
SCLC-A
R


cg02842704
chr5: 151305746
GLRA1.TSS1500
SCLC-A
R
chr5: 151304226-
S_Shore







151304824


cg02865101
chr7: 157779894
PTPRN2.GENEBODY
SCLC-A
R


cg05579861
chr7: 157631040
PTPRN2.GENEBODY
SCLC-A
F
chr7: 157631319-
N_Shore







157631615


cg06650260
chr1: 27240478
NROB2.EXON1
SCLC-A
R


cg07685977
chr10: 133036507
TCERG1L.GENEBODY
SCLC-A
F


cg13213923
chr17: 60885491
MARCH10.UTR5
SCLC-A
R
chr17: 60885408-
Island







60885857


cg19809865
chr14: 44976233
FSCB.EXON1
SCLC-A
R


cg20986887
chr6: 28887284
TRIM27.GENEBODY
SCLC-A
R
chr6: 28890951-
N_Shelf







28892013


cg23245485
chr12: 6484219
SCNN1A.UTR5
SCLC-A
R


cg24085344
chr17: 47485676
PHB.GENEBODY
SCLC-A
R


cg25148025
chr1: 164681267
PBX1.GENEBODY
SCLC-A
F


cg00787726
chr10: 86113284
FAM190B.UTR5
SCLC-A
F


cg03900492
chr7: 157345659
PTPRN2.GENEBODY
SCLC-A
R
chr7: 157346613-
N_Shore







157347069


cg04892919
chr2: 191272604
MFSD6.TSS1500
SCLC-A
R
chr2: 191272484-
Island







191273671


cg07942479
chr4: 185747981
ACSL1.TSS1500
SCLC-A
R
chr4: 185746557-
S_Shore







185747827


cg00448761
chr19: 6066102
RFX2.UTR5
SCLC-A
R


cg01792117
chr17: 27088227
C17orf63.GENEBODY
SCLC-A
F


cg02567323
chr2: 48671699
KLRAQ1.GENEBODY
SCLC-A
R
chr2: 48667559-
S_Shelf







48668355


cg08932665
chr11: 71937515
INPPL1.GENEBODY
SCLC-A
F
chr11: 71934247-
S_Shore







71936321


cg21380084
chr7: 157937891
PTPRN2.GENEBODY
SCLC-A
R
chr7: 157937614-
S_Shore







157937841


cg23632237
chr20: 30560483
XKR7.GENEBODY
SCLC-A
F
chr20: 30555901-
S_Shelf







30556502


cg25401010
chr18: 56529878
ZNF532.TSS200
SCLC-A
F
chr18: 56530395-
N_Shore







56531288


cg26312133
chr17: 71428204
SDK2.GENEBODY
SCLC-A
F
chr17: 71431621-
N_Shelf







71431878


cg01321816
chr15: 91358514
BLM.UTR3
SCLC-A
R
chr15: 91362445-
N_Shelf







91362658


cg03653377
chr7: 158107573
PTPRN2.GENEBODY
SCLC-A
F
chr7: 158109334-
N_Shore







158109594


cg24216770
chr20: 35091947
DLGAP4.GENEBODY
SCLC-A
F
chr20: 35089448-
S_Shore







35089998


cg25766748
chr19: 13614882
CACNA1A.GENEBODY
SCLC-A
F
chr19: 13616752-
N_Shore







13617267


cg26639747
chr7: 157590318
PTPRN2.GENEBODY
SCLC-A
R
chr7: 157593887-
N_Shelf







157594128


cg27388763
chr17: 44648385
ARL17A.GENEBODY
SCLC-A
R


cg00362322
chr16: 88704230
IL17C.TSS1500
SCLC-A
F
chr16: 88706211-
N_Shore







88706492


cg04874261
chr3: 71773745
EIF4E3.GENEBODY
SCLC-A
F
chr3: 71773826-
N_Shore







71774873


cg09130676
chr7: 158220856
PTPRN2.GENEBODY
SCLC-A
R
chr7: 158217851-
S_Shore







158220709


cg18011401
chr19: 13617366
CACNA1A.TSS200
SCLC-A
F
chr19: 13616752-
S_Shore







13617267


cg19307406
chr1: 167874258
ADCY10.UTR5
SCLC-A
R


cg19404354
chr1: 202093479
GPR37L1.GENEBODY
SCLC-A
F


cg19637113
chr15: 74528522
CCDC33.TSS200
SCLC-A
F


cg19726712
chr8: 98790327
LAPTM4B.GENEBODY
SCLC-A
F
chr8: 98787835-
S_Shore







98788874


cg23969274
chr6: 116851736
FAM26D.UTR5
SCLC-A
R


cg13024807
chr6: 53152718
ELOVL5.GENEBODY
SCLC-A
R


cg01100465
chr7: 157585095
PTPRN2.GENEBODY
SCLC-A
F
chr7: 157586711-
N_Shore







157587112


cg04373993
chr7: 157570916
PTPRN2.GENEBODY
SCLC-A
F
chr7: 157568163-
S_Shelf







157568404


cg05046377
chr11: 4927915
OR51A7.TSS1500
SCLC-A
F


cg06160809
chr2: 217559688
IGFBP5.UTR5
SCLC-A
F
chr2: 217559039-
S_Shore







217559484


cg06676049
chr2: 23839842
KLHL29.GENEBODY
SCLC-A
R


cg06912665
chr5: 154092290
LARP1.TSS200
SCLC-A
R


cg07927098
chr7: 157866704
PTPRN2.GENEBODY
SCLC-A
R


cg09644722
chr17: 60885519
MARCH10.UTR5
SCLC-A
R
chr17: 60885408-
Island







60885857


cg15726025
chr1: 32681995
C1orf91.UTR3
SCLC-A
F


cg19188359
chr20: 2312099
TGM3.GENEBODY
SCLC-A
R
chr20: 2308778-2309042
S_Shelf


cg19890739
chr16: 85723539
GINS2.TSS1500
SCLC-A
R
chr16: 85722209-
S_Shore







85722941


cg23309969
chr18: 56529866
ZNF532.TSS200
SCLC-A
F
chr18: 56530395-
N_Shore







56531288


cg25507001
chr5: 137475288
NME5.TSS200
SCLC-A
R


cg26546155
chr16: 57269635
RSPRY1.GENEBODY
SCLC-A
F


cg01520105
chr6: 111887243
TRAF3IP2.GENEBODY
SCLC-A
R


cg04911819
chr10: 24504859
KIAA1217.GENEBODY
SCLC-A
F


cg08471739
chr3: 129312902
PLXND1.GENEBODY
SCLC-A
F


cg15120341
chr13: 114238565
TFDP1.TSS1500
SCLC-A
F


cg01277983
chr22: 43835600
MPPED1.GENEBODY
SCLC-A
F


cg01942646
chr1: 27240694
NROB2.TSS200
SCLC-A
R


cg02639667
chr5: 154092321
LARP1.TSS200
SCLC-A
F


cg08353938
chr2: 217227472
MARCH4.GENEBODY
SCLC-A
R


cg26912251
chr6: 168970824
SMOC2.GENEBODY
SCLC-A
R
chr6: 168972516-
N_Shore







168974109


cg03308120
chr7: 157933784
PTPRN2.GENEBODY
SCLC-A
F
chr7: 157937614-
N_Shelf







157937841


cg07015608
chr7: 158114303
PTPRN2.GENEBODY
SCLC-A
R
chr7: 158110569-
S_Shelf







158110881


cg08698159
chr17: 27294743
SEZ6.GENEBODY
SCLC-A
R


cg08725319
chr7: 157334751
PTPRN2.GENEBODY
SCLC-A
R


cg13531977
chr9: 112013420
EPB41L4B.GENEBODY
SCLC-A
R


cg19779605
chr11: 4703553
OR51E2.GENEBODY
SCLC-A
R


cg20448594
chr7: 73940352
GTF2IRD1.GENEBODY
SCLC-A
R


cg21857959
chr3: 182896995
MCF2L2.UTR3
SCLC-A
F
chr3: 182896920-
Island







182897381


cg26572499
chr15: 22929910
CYFIP1.GENEBODY
SCLC-A
R


cg04198210
chr15: 74528606
CCDC33.TSS200
SCLC-A
F


cg05204104
chr2: 235403141
ARL4C.UTR3
SCLC-A
R
chr2: 235404502-
N_Shore







235406541


cg05822926
chr7: 8302235
ICA1.TSS200
SCLC-A
F
chr7: 8301031-8302252
Island


cg18360873
chr10: 133051669
TCERG1L.GENEBODY
SCLC-A
F


cg00610577
chr12: 12008666
ETV6.GENEBODY
SCLC-A
R


cg07675656
chr16: 2105015
TSC2.GENEBODY
SCLC-A
R
chr16: 2105014-2105390
Island


cg11812748
chr1: 246733057
CNST.UTR5
SCLC-A
F
chr1: 246729207-
S_Shelf







246730276


cg14178173
chr7: 157495532
PTPRN2.GENEBODY
SCLC-A
F
chr7: 157494510-
S_Shore







157494739


cg20724810
chr3: 182897196
MCF2L2.GENEBODY
SCLC-A
R
chr3: 182896920-
Island







182897381


cg21831937
chr15: 57519802
TCF12.GENEBODY
SCLC-A
F


cg22049038
chr7: 146332766
CNTNAP2.GENEBODY
SCLC-A
R


cg23613317
chr5: 154092109
LARP1.TSS1500
SCLC-A
R


cg24580782
chr1: 27240365
NROB2.EXON1
SCLC-A
R


cg25975382
chr7: 157532236
PTPRN2.GENEBODY
SCLC-A
F


cg01536803
chr7: 157968578
PTPRN2.GENEBODY
SCLC-A
F


cg06070324
chr15: 75322058
PPCDC.GENEBODY
SCLC-A
R


cg06413087
chr7: 157929609
PTPRN2.GENEBODY
SCLC-A
F


cg08203715
chr11: 126226154
ST3GAL4.EXON1
SCLC-A
R
chr11: 126225355-
S_Shore







126226073


cg15067687
chr7: 127658301
SND1.GENEBODY
SCLC-A
F


cg15428620
chr10: 102792835
SFXN3.GENEBODY
SCLC-A
F
chr10: 102790820-
S_Shore







102791049


cg16681199
chr6: 70990268
COL9A1.GENEBODY
SCLC-A
R
chr6: 70992040-
N_Shore







70992912


cg17976873
chr14: 23352295
REM2.TSS200
SCLC-A
F
chr14: 23355738-
N_Shelf







23356402


cg18717689
chr9: 116971578
MIR455.TSS200
SCLC-A
R


cg25145687
chr11: 1606664
HCCA2.GENEBODY
SCLC-A
R


cg01154505
chr2: 112940409
FBLN7.GENEBODY
SCLC-A
F
chr2: 112939287-
S_Shore







112939563


cg03071245
chr13: 37463034
SMAD9.UTR5
SCLC-A
F


cg03527077
chr7: 158059704
PTPRN2.GENEBODY
SCLC-A
R
chr7: 158060894-
N_Shore







158061100


cg07979652
chr7: 157934005
PTPRN2.GENEBODY
SCLC-A
R
chr7: 157937614-
N_Shelf







157937841


cg09409457
chr7: 157954722
PTPRN2.GENEBODY
SCLC-A
F
chr7: 157956911-
N_Shelf







157957273


cg13169065
chr2: 166650947
GALNT3.TSS200
SCLC-A
F
chr2: 166649909-
Island







166650966


cg13619044
chr7: 30202350
C7orf41.UTR3
SCLC-A
R


cg15707428
chr2: 11679845
GREB1.TSS1500
SCLC-A
R


cg16287740
chr7: 128595046
TNPO3.UTR3
SCLC-A
R


cg19343518
chr6: 157508679
ARID1B.GENEBODY
SCLC-A
F


cg20632462
chr11: 20882850
NELL1.GENEBODY
SCLC-A
F


cg24129115
chr14: 23352488
REM2.EXON1
SCLC-A
F
chr14: 23355738-
N_Shelf







23356402


cg25439479
chr8: 92971562
RUNX1T1.UTR3
SCLC-A
F


cg02873384
chr11: 4936857
OR51G2.EXON1
SCLC-A
F


cg03892543
chr16: 84650330
COTL1.GENEBODY
SCLC-A
R
chr16: 84650960-
N_Shore







84651565


cg04466743
chr20: 19915794
RIN2.GENEBODY
SCLC-A
F


cg06424550
chr10: 12808422
CAMK1D.GENEBODY
SCLC-A
R


cg08886790
chr2: 111857973
ACOXL.GENEBODY
SCLC-A
LL


cg11959316
chr1: 57001742
PPAP2B.GENEBODY
SCLC-A
R


cg16396191
chr13: 42184765
KIAA0564.GENEBODY
SCLC-A
R


cg18352935
chr11: 4843021
OR51F2.EXON1
SCLC-A
R


cg21185990
chr7: 157835049
PTPRN2.GENEBODY
SCLC-A
F


cg07056138
chr8: 103120260
NCALD.UTR5
SCLC-A
F


cg07444408
chr4: 141218466
SCOC.UTR5
SCLC-A
F


cg08871354
chr16: 85723489
GINS2.TSS1500
SCLC-A
R
chr16: 85722209-
S_Shore







85722941


cg09027472
chr7: 157981337
PTPRN2.GENEBODY
SCLC-A
F
chr7: 157980786-
Island







157981462


cg11786338
chr18: 56809717
SEC11C.GENEBODY
SCLC-A
F
chr18: 56806608-
S_Shelf







56807425


cg14537549
chr10: 12393185
CAMK1D.GENEBODY
SCLC-A
R
chr10: 12390802-
S_Shore







12392589


cg16696476
chr17: 8191344
RANGRF.TSS1500
SCLC-A
R
chr17: 8191864-8192495
N_Shore


cg20239333
chr10: 133111331
TCERG1L.TSS1500
SCLC-A
F
chr10: 133109193-
S_Shore







133111052


cg21088119
chr8: 11251471
C8orf12.GENEBODY
SCLC-A
F


cg23758354
chr7: 157434590
PTPRN2.GENEBODY
SCLC-A
R


cg27266257
chr10: 5707799
ASB13.GENEBODY
SCLC-A
F
chr10: 5707980-5708798
N_Shore


cg03345925
chr8: 144599347
ZC3H3.GENEBODY
SCLC-A
F
chr8: 144601691-
N_Shelf







144601895


cg07998072
chr16: 19425853
TMC5.UTR5
SCLC-A
F
chr16: 19421816-
S_Shelf







19422498


cg08917718
chr3: 52002169
PCBP4.TSS1500
SCLC-A
R


cg09127540
chr7: 157671453
PTPRN2.GENEBODY
SCLC-A
R
chr7: 157669879-
S_Shore







157670095


cg10633463
chr17: 79197669
AZI1.TSS1500
SCLC-A
R
chr17: 79196345-
S_Shore







79197419


cg11803278
chr7: 157951799
PTPRN2.GENEBODY
SCLC-A
F
chr7: 157951254-
Island







157951800


cg22797644
chr6: 34206491
HMGA1.UTR5
SCLC-A
F
chr6: 34202567-
S_Shore







34206193


cg22994649
chr7: 157641916
PTPRN2.GENEBODY
SCLC-A
R


cg00572756
chr7: 157863106
PTPRN2.GENEBODY
SCLC-A
R


cg02079584
chr15: 74528719
CCDC33.EXON1
SCLC-A
F


cg02111655
chr10: 30338246
KIAA1462.UTR5
SCLC-A
R


cg03332546
chr19: 16553887
EPS15L1.GENEBODY
SCLC-A
F


cg03660606
chr7: 157659983
PTPRN2.GENEBODY
SCLC-A
F
chr7: 157659433-
Island







157660322


cg11857514
chr12: 122151762
TMEM120B.GENEBODY
SCLC-A
F
chr12: 122150513-
S_Shore







122151091


cg14037240
chr10: 5707981
ASB13.GENEBODY
SCLC-A
R
chr10: 5707980-5708798
Island


cg17356036
chr2: 240213057
HDAC4.GENEBODY
SCLC-A
R


cg17985311
chr1: 42801965
FOXJ3.TSS1500
SCLC-A
R
chr1: 42800265-
S_Shore







42801370


cg19126954
chr7: 157616612
PTPRN2.GENEBODY
SCLC-A
F
chr7: 157618856-
N_Shelf







157619302


cg25743482
chr11: 19775505
NAV2.GENEBODY
SCLC-A
F


cg02007867
chr7: 157786536
PTPRN2.GENEBODY
SCLC-A
R


cg02902261
chr7: 72991150
TBL2.GENEBODY
SCLC-A
R
chr7: 72992434-
N_Shore







72993397


cg06938143
chr8: 11251609
C8orf12.GENEBODY
SCLC-A
R


cg08850729
chr1: 60036715
FGGY.GENEBODY
SCLC-A
R


cg08989212
chr21: 36096051
NCRNA00160.TSS200
SCLC-A
R


cg12193099
chr6: 169654018
THBS2.UTR5
SCLC-A
R


cg12275410
chr10: 135123239
ZNF511.GENEBODY
SCLC-A
R
chr10: 135123238-
Island







135123448


cg12356107
chr20: 22567037
FOXA2.TSS1500
SCLC-A
R
chr20: 22566821-
Island







22567055


cg15252509
chr18: 56337165
MALT1.TSS1500
SCLC-A
R
chr18: 56338211-
N_Shore







56339277


cg16289848
chr4: 79231477
FRAS1.GENEBODY
SCLC-A
F


cg00827176
chr8: 21885702
NPM2.GENEBODY
SCLC-A
R
chr8: 21882245-
S_Shelf







21882883


cg01511231
chr1: 1109676
TTLL10.UTR5
SCLC-A
F
chr1: 1109314-1110145
Island


cg08202399
chr16: 14280512
MKL2.GENEBODY
SCLC-A
F


cg14122506
chr9: 116060914
RNF183.UTR5
SCLC-A
R


cg16934969
chr2: 173607848
RAPGEF4.GENEBODY
SCLC-A
R


cg19755171
chr17: 79197747
AZI1.TSS1500
SCLC-A
R
chr17: 79196345-
S_Shore







79197419


cg20649298
chr20: 22545407
C20orf56.GENEBODY
SCLC-A
R
chr20: 22548967-
N_Shelf







22549720


cg22420514
chr7: 157997479
PTPRN2.GENEBODY
SCLC-A
F
chr7: 157996642-
S_Shore







157997027


cg23997290
chr20: 22402746
LOC284788.TSS1500
SCLC-A
F


cg27308682
chr7: 157637500
PTPRN2.GENEBODY
SCLC-A
F


cg01310118
chr6: 168855168
SMOC2.GENEBODY
SCLC-A
R


cg06155341
chr11: 66048759
CNIH2.GENEBODY
SCLC-A
R
chr11: 66049750-
N_Shore







66050229


cg07143635
chr16: 11681487
LITAF.TSS200
SCLC-A
F
chr16: 11680008-
S_Shore







11681275


cg07551677
chr8: 28570561
EXTL3.UTR5
SCLC-A
R
chr8: 28573597-
N_Shelf







28573840


cg13071618
chr8: 144599125
ZC3H3.GENEBODY
SCLC-A
R
chr8: 144601691-
N_Shelf







144601895


cg14706245
chr7: 157536727
PTPRN2.GENEBODY
SCLC-A
F


cg15175716
chr11: 64120685
CCDC88B.GENEBODY
SCLC-A
R


cg15504747
chr3: 129312979
PLXND1.GENEBODY
SCLC-A
R


cg20573218
chr3: 181409863
SOX2OT.GENEBODY
SCLC-A
F
chr3: 181413014-
N_Shelf







181414022


cg20825710
chr11: 1620352
HCCA2.GENEBODY
SCLC-A
R


cg23869743
chr10: 99611477
GOLGA7B.GENEBODY
SCLC-A
F
chr10: 99609425-
S_Shore







99610116


cg24119607
chr5: 139047739
CXXC5.UTR5
SCLC-A
F
chr5: 139047905-
N_Shore







139048235


cg25809301
chr3: 71179811
FOXP1.GENEBODY
SCLC-A
F


cg00781208
chr12: 64433590
SRGAP1.GENEBODY
SCLC-A
R


cg01282269
chr21: 41515306
DSCAM.GENEBODY
SCLC-A
F
chr21: 41516237-
N_Shore







41516472


cg02098619
chr1: 8689772
RERE.GENEBODY
SCLC-A
R


cg02704103
chr3: 72846991
SHQ1.GENEBODY
SCLC-A
R


cg02704570
chr7: 157647109
PTPRN2.GENEBODY
SCLC-A
F
chr7: 157647800-
N_Shore







157648007


cg04188351
chr11: 33744823
CD59.UTR5
SCLC-A
R


cg04545268
chr7: 157653809
PTPRN2.GENEBODY
SCLC-A
F


cg04583813
chr10: 560323
DIP2C.GENEBODY
SCLC-A
F


cg06287775
chr7: 4784174
FOXK1.GENEBODY
SCLC-A
R
chr7: 4784820-4785058
N_Shore


cg06324554
chr7: 157495841
PTPRN2.GENEBODY
SCLC-A
R
chr7: 157494510-
S_Shore







157494739


cg07530194
chr17: 78808450
RPTOR.GENEBODY
SCLC-A
R


cg09215582
chr4: 71575507
RUFY3.GENEBODY
SCLC-A
R
chr4: 71570147-
S_Shelf







71571626


cg16177693
chr1: 27240669
NROB2.TSS200
SCLC-A
R


cg18587271
chr16: 46917496
GPT2.TSS1500
SCLC-A
F
chr16: 46917849-
N_Shore







46918957


cg19149693
chr3: 114599007
ZBTB20.UTR5
SCLC-A
F


cg23694187
chr7: 157335188
PTPRN2.GENEBODY
SCLC-A
F


cg23861617
chr4: 83422170
TMEM150C.GENEBODY
SCLC-A
F


cg00909926
chr1: 216774208
ESRRG.GENEBODY
SCLC-A
R
chr1: 216774339-
N_Shore







216774734


cg00932063
chr10: 126234138
LHPP.GENEBODY
SCLC-A
R


cg02323550
chr7: 157660321
PTPRN2.GENEBODY
SCLC-A
F
chr7: 157659433-
Island







157660322


cg03170878
chr7: 157630174
PTPRN2.GENEBODY
SCLC-A
F
chr7: 157631319-
N_Shore







157631615


cg05104995
chr10: 49460249
FRMPD2.GENEBODY
SCLC-A
F


cg05336188
chr19: 18959506
UPF1.GENEBODY
SCLC-A
F


cg05987961
chr7: 158059396
PTPRN2.GENEBODY
SCLC-A
F
chr7: 158060894-
N_Shore







158061100


cg11376706
chr7: 157514626
PTPRN2.GENEBODY
SCLC-A
F


cg15752885
chr7: 158255389
PTPRN2.GENEBODY
SCLC-A
F


cg19487718
chr4: 185747708
ACSL1.TSS1500
SCLC-A
R
chr4: 185746557-
Island







185747827


cg27282206
chr7: 158179313
PTPRN2.GENEBODY
SCLC-A
R


cg00108938
chr7: 157633252
PTPRN2.GENEBODY
SCLC-A
F
chr7: 157631319-
S_Shore







157631615


cg11111139
chr7: 157620685
PTPRN2.GENEBODY
SCLC-A
R
chr7: 157618856-
S_Shore







157619302


cg03347095
chr7: 158157967
PTPRN2.GENEBODY
SCLC-A
R


cg04772948
chr20: 22401407
LOC284788.TSS200
SCLC-A
R


cg07011711
chr11: 61467286
DAGLA.UTR5
SCLC-A
R


cg07037223
chr7: 157618857
PTPRN2.GENEBODY
SCLC-A
R
chr7: 157618856-
Island







157619302


cg10798171
chr7: 8302301
ICA1.TSS200
SCLC-A
F
chr7: 8301031-8302252
S_Shore


cg10817855
chr7: 99019985
PTCD1.GENEBODY
SCLC-A
F
chr7: 99016967-
S_Shelf







99017289


cg10932907
chr11: 129723947
TMEM45B.GENEBODY
SCLC-A
F


cg12030523
chr5: 126984765
CTXN3.EXON1
SCLC-A
R


cg13808071
chr2: 11679872
GREB1.TSS1500
SCLC-A
R


cg19285478
chr11: 63849412
MACROD1.GENEBODY
SCLC-A
F
chr11: 63852803-
N_Shelf







63853082


cg19564367
chr4: 7941852
AFAP1.TSS200
SCLC-A
F
chr4: 7940563-7941853
Island


cg24324985
chr20: 22566884
FOXA2.TSS1500
SCLC-A
R
chr20: 22566821-
Island







22567055


cg26160008
chr12: 6451035
TNFRSF1A.UTR5
SCLC-A
R


cg05358575
chr2: 26764961
OTOF.GENEBODY
SCLC-A
F


cg11855643
chr1: 184473341
C1orf21.GENEBODY
SCLC-A
R


cg13810707
chr7: 122018993
CADPS2.GENEBODY
SCLC-A
R


cg14974147
chr3: 121310923
FBXO40.TSS1500
SCLC-A
F


cg00035220
chr7: 158197980
PTPRN2.GENEBODY
SCLC-A
F
chr7: 158198545-
N_Shore







158198907


cg04112626
chr4: 79861272
PAQR3.TSS1500
SCLC-A
F
chr4: 79860213-
S_Shore







79860745


cg04873861
chr3: 12525454
TSEN2.TSS1500
SCLC-A
F
chr3: 12525749-
N_Shore







12526346


cg07011231
chr2: 73329813
RAB11FIP5.GENEBODY
SCLC-A
F


cg15000071
chr3: 134889493
EPHB1.GENEBODY
SCLC-A
F


cg15090562
chr1: 6534449
PLEKHG5.GENEBODY
SCLC-A
F
chr1: 6530536-6531814
S_Shelf


cg18187658
chr1: 230294691
GALNT2.GENEBODY
SCLC-A
R


cg21147709
chr1: 12004662
PLOD1.GENEBODY
SCLC-A
R


cg23313445
chr11: 4792272
OR51F1.TSS1500
SCLC-A
F


cg23636833
chr7: 157514822
PTPRN2.GENEBODY
SCLC-A
F


cg26713273
chr12: 11906243
ETV6.GENEBODY
SCLC-A
R


cg01431993
chr2: 182542864
NEUROD1.GENEBODY
SCLC-A
R


cg01570265
chr14: 70180751
KIAA0247.UTR3
SCLC-A
R


cg03599855
chr8: 119073725
EXT1.GENEBODY
SCLC-A
R


cg04303033
chr7: 157586345
PTPRN2.GENEBODY
SCLC-A
F
chr7: 157586711-
N_Shore







157587112


cg05241143
chr7: 157916636
PTPRN2.GENEBODY
SCLC-A
F
chr7: 157918704-
N_Shelf







157919409


cg05430989
chr3: 133749309
SLCO2A1.TSS1500
SCLC-A
F
chr3: 133747920-
S_Shore







133748266


cg05998486
chr7: 150645092
KCNH2.GENEBODY
SCLC-A
R
chr7: 150644455-
S_Shore







150644767


cg14171944
chr9: 126323477
DENND1A.GENEBODY
SCLC-A
F


cg21443274
chr8: 106782921
ZFPM2.GENEBODY
SCLC-A
R


cg11717251
chr7: 157589770
PTPRN2.GENEBODY
SCLC-A
F
chr7: 157586711-
S_Shelf







157587112


cg25481630
chr7: 157499673
PTPRN2.GENEBODY
SCLC-A
R
chr7: 157503469-
N_Shelf







157504144


cg02367316
chr7: 39125198
POU6F2.GENEBODY
SCLC-A
F


cg03697708
chr19: 13617549
CACNA1A.TSS1500
SCLC-A
F
chr19: 13616752-
S_Shore







13617267


cg04983349
chr6: 80381447
SH3BGRL2.GENEBODY
SCLC-A
R


cg08570034
chr5: 175227702
CPLX2.UTR5
SCLC-A
F
chr5: 175223609-
S_Shelf







175224679


cg09805271
chr11: 5010562
MMP26.GENEBODY
SCLC-A
R


cg10531355
chr5: 79489249
SERINC5.GENEBODY
SCLC-A
R


cg13649658
chr9: 140680393
EHMT1.GENEBODY
SCLC-A
F
chr9: 140683120-
N_Shelf







140683774


cg14779376
chr7: 157341829
PTPRN2.GENEBODY
SCLC-A
R


cg18769909
chr7: 157616107
PTPRN2.GENEBODY
SCLC-A
F
chr7: 157618856-
N_Shelf







157619302


cg20808813
chr7: 157663646
PTPRN2.GENEBODY
SCLC-A
F
chr7: 157666069-
N_Shelf







157666399


cg26562638
chr1: 226130366
LEFTY2.TSS1500
SCLC-A
F
chr1: 226127112-
S_Shelf







226127695


cg01863682
chr2: 182545771
NEUROD1.TSS1500
SCLC-A
R
chr2: 182547873-
N_Shelf







182549177


cg02573468
chr15: 41224537
DLL4.GENEBODY
SCLC-A
F
chr15: 41217789-
S_Shore







41223180


cg02860921
chr7: 157506297
PTPRN2.GENEBODY
SCLC-A
F
chr7: 157503469-
S_Shelf







157504144


cg04087039
chr7: 157697459
PTPRN2.GENEBODY
SCLC-A
R
chr7: 157694387-
S_Shelf







157694661


cg06455686
chr6: 168971081
SMOC2.GENEBODY
SCLC-A
F
chr6: 168972516-
N_Shore







168974109


cg10122877
chr4: 37585361
C4orf19.TSS1500
SCLC-A
F


cg10288307
chr7: 157563602
PTPRN2.GENEBODY
SCLC-A
R
chr7: 157560974-
S_Shelf







157561195


cg11261691
chr20: 30914444
KIF3B.GENEBODY
SCLC-A
R


cg13915179
chr7: 158038007
PTPRN2.GENEBODY
SCLC-A
R
chr7: 158037708-
Island







158038048


cg19280540
chr19: 16553711
EPS15L1.GENEBODY
SCLC-A
R


cg22053861
chr11: 65318683
LTBP3.GENEBODY
SCLC-A
R
chr11: 65321225-
N_Shelf







65321823


cg22705918
chr2: 25518238
DNMT3A.GENEBODY
SCLC-A
F


cg22719871
chr11: 66105148
BRMS1.UTR3
SCLC-A
R
chr11: 66102024-
S_Shelf







66102279


cg24060173
chr1: 205488243
CDK18.UTR5
SCLC-A
R


cg25001924
chr7: 157919982
PTPRN2.GENEBODY
SCLC-A
R
chr7: 157918704-
S_Shore







157919409


cg26816432
chr7: 158165951
PTPRN2.GENEBODY
SCLC-A
F


cg27099497
chr7: 158269297
PTPRN2.GENEBODY
SCLC-A
F


cg27324698
chr7: 157916687
PTPRN2.GENEBODY
SCLC-A
F
chr7: 157918704-
N_Shelf







157919409


cg01181415
chr12: 16757954
LMO3.UTR5
SCLC-A
R


cg05552035
chr8: 37699239
GPR124.GENEBODY
SCLC-A
F
chr8: 37698846-
Island







37699931


cg06818217
chr12: 97887662
RMST.GENEBODY
SCLC-A
R


cg08141495
chr18: 31739521
NOL4.GENEBODY
SCLC-A
F
chr18: 31739047-
Island







31739522


cg09643186
chr14: 65409452
GPX2.EXON1
SCLC-A
F


cg13432032
chr15: 76692444
SCAPER.GENEBODY
SCLC-A
F


cg17611686
chr20: 22547532
C20orf56.GENEBODY
SCLC-A
F
chr20: 22548967-
N_Shore







22549720


cg20821442
chr7: 105279882
ATXN7L1.GENEBODY
SCLC-A
F


cg24040043
chr1: 207224982
YOD1.TSS1500
SCLC-A
F
chr1: 207226281-
N_Shore







207226842


cg24524099
chr7: 157643007
PTPRN2.GENEBODY
SCLC-A
R


cg02546690
chr11: 17834480
SERGEF.GENEBODY
SCLC-A
R


cg02932780
chr6: 31762353
VARS.GENEBODY
SCLC-A
R
chr6: 31763240-
N_Shore







31763905


cg04983296
chr4: 79861284
PAQR3.TSS1500
SCLC-A
F
chr4: 79860213-
S_Shore







79860745


cg09367807
chr11: 1577706
HCCA2.GENEBODY
SCLC-A
R
chr11: 1577705-1579091
Island


cg11199014
chr19: 39798563
LRFN1.GENEBODY
SCLC-A
R
chr19: 39797786-
Island







39799250


cg14468481
chr7: 157561104
PTPRN2.GENEBODY
SCLC-A
R
chr7: 157560974-
Island







157561195


cg21759685
chr3: 46400618
CCR2.UTR3
SCLC-A
F


cg23629187
chr8: 125576109
MTSS1.GENEBODY
SCLC-A
R


cg00341732
chr22: 31479561
SMTN.GENEBODY
SCLC-A
F
chr22: 31480774-
N_Shore







31481373


cg00362285
chr1: 236444212
ERO1LB.GENEBODY
SCLC-A
F
chr1: 236444603-
N_Shore







236445700


cg01387450
chr2: 23839710
KLHL29.GENEBODY
SCLC-A
R


cg01557792
chr14: 70162755
KIAA0247.GENEBODY
SCLC-A
F


cg07926025
chr9: 14722864
CER1.TSS200
SCLC-A
R


cg11939450
chr20: 18024215
OVOL2.GENEBODY
SCLC-A
R


cg14119936
chr11: 4791012
OR51F1.EXON1
SCLC-A
F


cg15727524
chr7: 157531216
PTPRN2.GENEBODY
SCLC-A
F


cg16615040
chr21: 41516861
DSCAM.GENEBODY
SCLC-A
R
chr21: 41516237-
S_Shore







41516472


cg17491449
chr4: 3344154
RGS12.GENEBODY
SCLC-A
F
chr4: 3341783-3342021
S_Shelf


cg17599372
chr7: 157894874
PTPRN2.GENEBODY
SCLC-A
F
chr7: 157890656-
S_Shelf







157891557


cg22016731
chr1: 40311142
TRIT1.GENEBODY
SCLC-A
F


cg22792988
chr5: 76376904
SNORA47.TSS1500
SCLC-A
F
chr5: 76372882-
S_Shelf







76373720


cg23919844
chr13: 111819481
ARHGEF7.GENEBODY
SCLC-A
R


cg25680145
chr6: 125623414
HDDC2.TSS200
SCLC-A
F
chr6: 125622704-
S_Shore







125623117


cg26480662
chr7: 157778593
PTPRN2.GENEBODY
SCLC-A
R


cg26674966
chr15: 22929993
CYFIP1.GENEBODY
SCLC-A
R


cg01782132
chr16: 28936054
RABEP2.GENEBODY
SCLC-A
R
chr16: 28936053-
Island







28937036


cg03788215
chr18: 76757841
SALL3.UTR3
SCLC-A
F
chr18: 76751939-
S_Shelf







76755549


cg06899237
chr6: 153353519
RGS17.GENEBODY
SCLC-A
R


cg08278648
chr17: 27503704
MYO18A.UTR5
SCLC-A
R
chr17: 27503598-
Island







27504014


cg08450080
chr7: 157919807
PTPRN2.GENEBODY
SCLC-A
R
chr7: 157918704-
S_Shore







157919409


cg12699647
chr17: 80401857
C17orf62.UTR3
SCLC-A
R
chr17: 80401644-
Island







80401858


cg13917127
chr9: 116932436
COL27A1.GENEBODY
SCLC-A
F
chr9: 116930004-
S_Shelf







116930368


cg15578140
chr7: 147718109
MIR548F3.GENEBODY
SCLC-A
R


cg17323383
chr3: 182896670
MCF2L2.UTR3
SCLC-A
F
chr3: 182896920-
N_Shore







182897381


cg18284875
chr7: 157777033
PTPRN2.GENEBODY
SCLC-A
F


cg20018344
chr20: 3204138
ITPA.UTR3
SCLC-A
R


cg21733013
chr7: 22359568
RAPGEF5.UTR5
SCLC-A
R


cg23606244
chr11: 4704115
OR51E2.UTR5
SCLC-A
F


cg23808337
chr7: 158267402
PTPRN2.GENEBODY
SCLC-A
R


cg24424217
chr10: 135123421
ZNF511.GENEBODY
SCLC-A
F
chr10: 135123238-
Island







135123448


cg25455408
chr19: 42274924
CEACAM6.UTR3
SCLC-A
R


cg17015844
chr12: 103352694
ASCL1.EXON1
SCLC-A
F
chr12: 103351579-
Island







103352695


cg00574412
chr17: 27892866
ABHD15.GENEBODY
SCLC-A
F
chr17: 27893086-
N_Shore







27896078


cg05012972
chr7: 158250129
PTPRN2.GENEBODY
SCLC-A
R
chr7: 158250128-
Island







158250497


cg10801633
chr1: 10579190
PEX14.GENEBODY
SCLC-A
R


cg11623476
chr7: 2566027
LFNG.GENEBODY
SCLC-A
F
chr7: 2565872-2566114
Island


cg12661624
chr7: 157957646
PTPRN2.GENEBODY
SCLC-A
F
chr7: 157956911-
S_Shore







157957273


cg13102244
chr7: 158198569
PTPRN2.GENEBODY
SCLC-A
R
chr7: 158198545-
Island







158198907


cg14527645
chr9: 116977924
COL27A1.GENEBODY
SCLC-A
F


cg14670303
chr6: 169654035
THBS2.UTR5
SCLC-A
R


cg18280382
chr11: 126225996
ST3GAL4.TSS200
SCLC-A
F
chr11: 126225355-
Island







126226073


cg18438823
chr11: 4676365
OR51E1.UTR3
SCLC-A
R


cg19268477
chr7: 157951471
PTPRN2.GENEBODY
SCLC-A
F
chr7: 157951254-
Island







157951800


cg21413492
chr6: 70990226
COL9A1.GENEBODY
SCLC-A
F
chr6: 70992040-
N_Shore







70992912


cg22868951
chr4: 129767588
PHF17.GENEBODY
SCLC-A
R


cg27572053
chr7: 157513908
PTPRN2.GENEBODY
SCLC-A
F


cg00161124
chr1: 234366259
SLC35F3.GENEBODY
SCLC-A
R
chr1: 234367135-
N_Shore







234367496


cg00973286
chr12: 6451130
TNFRSF1A.UTR5
SCLC-A
F


cg02544257
chr16: 70510663
FUK.GENEBODY
SCLC-A
R
chr16: 70507026-
S_Shelf







70507246


cg03561416
chr6: 157254584
ARID1B.GENEBODY
SCLC-A
F


cg07773582
chr16: 4845285
LOC440335.TSS200
SCLC-A
R


cg08335767
chr6: 34206495
HMGA1.UTR5
SCLC-A
F
chr6: 34202567-
S_Shore







34206193


cg08514594
chr7: 157874020
PTPRN2.GENEBODY
SCLC-A
F


cg09046979
chr16: 28333134
SBK1.UTR3
SCLC-A
R
chr16: 28331225-
S_Shore







28332489


cg10055471
chr1: 27240319
NROB2.EXON1
SCLC-A
R


cg11809826
chr6: 168918901
SMOC2.GENEBODY
SCLC-A
F
chr6: 168918596-
Island







168918902


cg12286857
chr7: 157530016
PTPRN2.GENEBODY
SCLC-A
F
chr7: 157524157-
S_Shelf







157526741


cg14495729
chr7: 158283266
PTPRN2.GENEBODY
SCLC-A
R
chr7: 158282214-
Island







158283382


cg15408722
chr7: 157866922
PTPRN2.GENEBODY
SCLC-A
F


cg16025118
chr12: 114273678
RBM19.GENEBODY
SCLC-A
F


cg18789624
chr7: 30516742
NOD1.UTR5
SCLC-A
F
chr7: 30517987-
N_Shore







30518610


cg20673767
chr7: 158061805
PTPRN2.GENEBODY
SCLC-A
R
chr7: 158060894-
S_Shore







158061100


cg20979979
chr4: 141218072
SCOC.UTR5
SCLC-A
R


cg22004830
chr7: 157595428
PTPRN2.GENEBODY
SCLC-A
F
chr7: 157593887-
S_Shore







157594128


cg24438178
chr11: 64120354
CCDC88B.GENEBODY
SCLC-A
F


cg25023666
chr21: 41585021
DSCAM.GENEBODY
SCLC-A
F


cg00235442
chr7: 157408294
PTPRN2.GENEBODY
SCLC-A
F
chr7: 157409846-
N_Shore







157410241


cg04435975
chr17: 46683047
LOC404266.GENEBODY
SCLC-A
F
chr17: 46685244-
N_Shelf







46685449


cg08462055
chr15: 64944023
ZNF609.GENEBODY
SCLC-A
R


cg09035925
chr20: 19915769
RIN2.GENEBODY
SCLC-A
R


cg13889415
chr9: 116943379
COL27A1.GENEBODY
SCLC-A
R


cg14799696
chr7: 157571491
PTPRN2.GENEBODY
SCLC-A
R
chr7: 157568163-
S_Shelf







157568404


cg18522715
chr7: 158298958
PTPRN2.GENEBODY
SCLC-A
F
chr7: 158301266-
N_Shelf







158301610


cg20139338
chr11: 64120656
CCDC88B.GENEBODY
SCLC-A
F


cg23178546
chr7: 157710554
PTPRN2.GENEBODY
SCLC-A
R


cg25613641
chr4: 140587143
MGST2.EXON1
SCLC-A
R


cg25710298
chr2: 286830
FAM150B.GENEBODY
SCLC-A
F
chr2: 287353-290099
N_Shore


cg01103601
chr2: 239288872
TRAF3IP1.GENEBODY
SCLC-A
R


cg01371493
chr6: 168916145
SMOC2.GENEBODY
SCLC-A
F
chr6: 168918596-
N_Shelf







168918902


cg01384111
chr2: 11679605
GREB1.TSS1500
SCLC-A
F


cg02651776
chr10: 27447805
MASTL.GENEBODY
SCLC-A
F
chr10: 27444133-
S_Shelf







27444494


cg03021296
chr7: 158060614
PTPRN2.GENEBODY
SCLC-A
F
chr7: 158060894-
N_Shore







158061100


cg04750536
chr20: 19915857
RIN2.GENEBODY
SCLC-A
R


cg07399355
chr1: 155163013
MUC1.TSS1500
SCLC-A
R
chr1: 155163434-
N_Shore







155163818


cg08271443
chr16: 4845348
LOC440335.TSS200
SCLC-A
R


cg08515646
chr7: 157394337
PTPRN2.GENEBODY
SCLC-A
F


cg11206084
chr7: 157780161
PTPRN2.GENEBODY
SCLC-A
F


cg13178597
chr6: 153405859
RGS17.UTR5
SCLC-A
F


cg14603031
chr7: 2563184
LFNG.GENEBODY
SCLC-A
R
chr7: 2563610-2564056
N_Shore


cg16848873
chr17: 46682308
LOC404266.GENEBODY
SCLC-A
F
chr17: 46685244-
N_Shelf







46685449


cg18780243
chr13: 32487268
EEF1DP3.GENEBODY
SCLC-A
R


cg20146030
chr2: 166650965
GALNT3.TSS200
SCLC-A
F
chr2: 166649909-
Island







166650966


cg25430878
chr10: 1257999
ADARB2.GENEBODY
SCLC-A
R


cg26808921
chr6: 134373925
SLC2A12.TSS200
SCLC-A
F


cg02660277
chr7: 157438616
PTPRN2.GENEBODY
SCLC-A
F
chr7: 157440024-
N_Shore







157442721


cg03204605
chr4: 7941837
AFAP1.TSS200
SCLC-A
F
chr4: 7940563-7941853
Island


cg03637218
chr5: 115209107
AP3S1.GENEBODY
SCLC-A
F


cg06233593
chr16: 337645
AXIN1.UTR3
SCLC-A
F
chr16: 335829-336034
S_Shore


cg07267845
chr7: 157345566
PTPRN2.GENEBODY
SCLC-A
R
chr7: 157346613-
N_Shore







157347069


cg07323947
chr10: 103896068
PPRC1.GENEBODY
SCLC-A
R
chr10: 103892659-
S_Shelf







103893590


cg08482167
chr6: 144066847
PHACTR2.GENEBODY
SCLC-A
R


cg08930672
chr7: 157932168
PTPRN2.GENEBODY
SCLC-A
R


cg09984136
chr6: 37190074
TMEM217.UTR5
SCLC-A
F


cg13847963
chr1: 24514220
IL28RA.TSS1500
SCLC-A
F
chr1: 24513540-
Island







24514477


cg14653284
chr2: 11679879
GREB1.UTR5
SCLC-A
R


cg14800014
chr5: 125800764
GRAMD3.GENEBODY
SCLC-A
R


cg16872357
chr7: 157529444
PTPRN2.GENEBODY
SCLC-A
R
chr7: 157524157-
S_Shelf







157526741


cg17086205
chr7: 157543597
PTPRN2.GENEBODY
SCLC-A
R


cg17284536
chr6: 166891902
RPS6KA2.GENEBODY
SCLC-A
R


cg18174678
chr1: 42801761
FOXJ3.TSS1500
SCLC-A
F
chr1: 42800265-
S_Shore







42801370


cg19476622
chr18: 20714485
CABLES1.TSS1500
SCLC-A
R
chr18: 20714968-
N_Shore







20717071


cg19871235
chr12: 71552569
TSPAN8.TSS1500
SCLC-A
F


cg23483563
chr2: 163625290
KCNH7.GENEBODY
SCLC-A
F


cg00332882
chr20: 22401271
LOC284788.GENEBODY
SCLC-A
F


cg01076708
chr11: 129689897
TMEM45B.UTR5
SCLC-A
F
chr11: 129685737-
S_Shelf







129686211


cg02708758
chr15: 74545009
CCDC33.GENEBODY
SCLC-A
R


cg02978297
chr1: 94057587
BCAR3.GENEBODY
SCLC-A
R


cg06579626
chr2: 73495921
FBXO41.GENEBODY
SCLC-A
R
chr2: 73495920-
Island







73496910


cg06998965
chr5: 68710808
MARVELD2.TSS200
SCLC-A
R
chr5: 68710807-
Island







68711520


cg07520608
chr2: 23627401
KLHL29.UTR5
SCLC-A
R


cg07696757
chr7: 44229001
GCK.EXON1
SCLC-A
R


cg08826152
chr17: 15869607
ADORA2B.GENEBODY
SCLC-A
R


cg09967440
chr10: 127444969
C10orf137.GENEBODY
SCLC-A
F


cg15016771
chr2: 235403218
ARL4C.UTR3
SCLC-A
R
chr2: 235404502-
N_Shore







235406541


cg15553397
chr1: 76695186
ST6GALNAC3.GENEBODY
SCLC-A
R


cg16666708
chr19: 17797733
UNC13A.GENEBODY
SCLC-A
F
chr19: 17797530-
Island







17797748


cg18351607
chr10: 124739543
PSTK.TSS200
SCLC-A
R
chr10: 124739792-
N_Shore







124740292


cg19502457
chr14: 65409354
GPX2.EXON1
SCLC-A
R


cg20464246
chr1: 216774397
ESRRG.GENEBODY
SCLC-A
R
chr1: 216774339-
Island







216774734


cg00119314
chr17: 48555610
RSAD1.TSS1500
SCLC-A
F
chr17: 48556004-
N_Shore







48556509


cg01861131
chr16: 4845708
LOC440335.GENEBODY
SCLC-A
R


cg02356647
chr7: 158102787
PTPRN2.GENEBODY
SCLC-A
R
chr7: 158103336-
N_Shore







158103601


cg03391854
chr7: 157961629
PTPRN2.GENEBODY
SCLC-A
F


cg04476846
chr5: 78791415
HOMER1.GENEBODY
SCLC-A
R


cg05234415
chr19: 38743744
PPP1R14A.GENEBODY
SCLC-A
R
chr19: 38746638-
N_Shelf







38747379


cg10471944
chr7: 157345246
PTPRN2.GENEBODY
SCLC-A
F
chr7: 157346613-
N_Shore







157347069


cg10481560
chr11: 1597444
HCCA2.GENEBODY
SCLC-A
R
chr11: 1595809-1596143
S_Shore


cg14249078
chr11: 117665480
DSCAML1.GENEBODY
SCLC-A
F
chr11: 117666634-
N_Shore







117668141


cg17114257
chr11: 72854156
FCHSD2.TSS1500
SCLC-A
F
chr11: 72852176-
Island







72854160


cg18645642
chr1: 8631756
RERE.GENEBODY
SCLC-A
R


cg19948253
chr11: 65318624
LTBP3.GENEBODY
SCLC-A
R
chr11: 65321225-
N_Shelf







65321823


cg23097035
chr7: 28396164
CREB5.UTR5
SCLC-A
R


cg23381267
chr14: 88787370
KCNK10.GENEBODY
SCLC-A
F
chr14: 88789600-
N_Shelf







88790493


cg25167574
chr4: 79861398
PAQR3.TSS1500
SCLC-A
F
chr4: 79860213-
S_Shore







79860745


cg25644224
chr7: 158195876
PTPRN2.GENEBODY
SCLC-A
R
chr7: 158198545-
N_Shelf







158198907


cg26527638
chr17: 79197398
AZI1.TSS1500
SCLC-A
R
chr17: 79196345-
Island







79197419


cg00405069
chr1: 52455390
RAB3B.UTR5
SCLC-A
R
chr1: 52455970-
N_Shore







52456453


cg03873826
chr16: 68407311
SMPD3.UTR5
SCLC-A
F
chr16: 68404907-
S_Shore







68406273


cg04937416
chr7: 157479272
PTPRN2.GENEBODY
SCLC-A
F
chr7: 157476886-
Island







157486719


cg04977856
chr14: 89886941
FOXN3.UTR5
SCLC-A
F
chr14: 89882421-
S_Shelf







89884278


cg11115622
chr14: 65169958
PLEKHG3.TSS1500
SCLC-A
R
chr14: 65170876-
N_Shore







65172007


cg16177633
chr1: 232172585
DISC1.UTR3
SCLC-A
R


cg16532223
chr1: 6542083
PLEKHG5.UTR5
SCLC-A
F
chr1: 6545143-6545559
N_Shelf


cg17429772
chr7: 158269409
PTPRN2.GENEBODY
SCLC-A
F


cg18943033
chr6: 168993309
SMOC2.GENEBODY
SCLC-A
R


cg21240812
chr8: 143483748
TSNARE1.UTR5
SCLC-A
F
chr8: 143484018-
N_Shore







143485051


cg23430388
chr3: 63429828
SYNPR.GENEBODY
SCLC-A
F


cg25503804
chr11: 46739832
F2.TSS1500
SCLC-A
R


cg02694994
chr7: 157612661
PTPRN2.GENEBODY
SCLC-A
R
chr7: 157612036-
S_Shore







157612316


cg05212138
chr20: 23063119
CD93.UTR3
SCLC-A
R


cg07265549
chr16: 27607018
KIAA0556.GENEBODY
SCLC-A
F


cg09350411
chr7: 157667935
PTPRN2.GENEBODY
SCLC-A
R
chr7: 157669879-
N_Shore







157670095


cg13794807
chr4: 153871752
FHDC1.GENEBODY
SCLC-A
R


cg15374582
chr7: 158250524
PTPRN2.GENEBODY
SCLC-A
F
chr7: 158247888-
S_Shore







158249312


cg25014026
chr8: 73735989
KCNB2.GENEBODY
SCLC-A
F


cg26775087
chr3: 15382808
SH3BP5.EXON1
SCLC-A
R


cg27373591
chr18: 70208064
CBLN2.GENEBODY
SCLC-A
F
chr18: 70208974-
N_Shore







70211790


cg01008164
chr11: 4825232
OR52R1.EXON1
SCLC-A
F


cg01008405
chr5: 139039026
CXXC5.UTR5
SCLC-A
F
chr5: 139040819-
N_Shore







139041028


cg01338378
chr7: 102036355
PRKRIP1.TSS1500
SCLC-A
F
chr7: 102036470-
N_Shore







102037017


cg01789980
chr5: 167743144
WWC1.GENEBODY
SCLC-A
R


cg04682791
chr6: 25313030
LRRC16A.GENEBODY
SCLC-A
F


cg08082862
chr16: 67807580
RANBP10.GENEBODY
SCLC-A
F


cg13917863
chr11: 4945892
OR51G1.TSS1500
SCLC-A
F


cg16642299
chr12: 7071383
MIR200C.TSS1500
SCLC-A
F


cg21126943
chr19: 42259395
CEACAM6.TSS200
SCLC-A
F


cg21316923
chr2: 121983716
TFCP2L1.GENEBODY
SCLC-A
F
chr2: 121983326-
Island







121983740


cg22054191
chr19: 42637630
POU2F2.TSS1500
SCLC-A
F
chr19: 42637277-
Island







42637684


cg22968167
chr11: 4945873
OR51G1.TSS1500
SCLC-A
F


cg23447996
chr9: 93564603
SYK.GENEBODY
SCLC-A
R
chr9: 93563775-
S_Shore







93564546


cg00537335
chr7: 157989340
PTPRN2.GENEBODY
SCLC-A
R


cg05161074
chr15: 42289885
PLA2G4E.GENEBODY
SCLC-A
F


cg13068215
chr1: 240286481
FMN2.GENEBODY
SCLC-A
R


cg16670736
chr7: 157777149
PTPRN2.GENEBODY
SCLC-A
F


cg21815508
chr7: 157530036
PTPRN2.GENEBODY
SCLC-A
R
chr7: 157524157-
S_Shelf







157526741


cg21881338
chr12: 125566189
AACS.GENEBODY
SCLC-A
F
chr12: 125569828-
N_Shelf







125570140


cg22123255
chr6: 30182088
TRIM26.TSS1500
SCLC-A
F
chr6: 30180933-
Island







30182187


cg23087306
chr10: 119294055
EMX2OS.GENEBODY
SCLC-A
F
chr10: 119293917-
Island







119297675


cg00455386
chr7: 140104086
RAB19.UTR5
SCLC-A
F


cg00679546
chr17: 60729882
MRC2.GENEBODY
SCLC-A
R
chr17: 60729645-
Island







60730269


cg01807748
chr1: 94534645
ABCA4.GENEBODY
SCLC-A
R


cg03758241
chr9: 116929797
COL27A1.GENEBODY
SCLC-A
R
chr9: 116930004-
N_Shore







116930368


cg13151425
chr7: 2561116
LFNG.GENEBODY
SCLC-A
R
chr7: 2558371-2559967
S_Shore


cg14415844
chr14: 91884659
CCDC88C.TSS1500
SCLC-A
F
chr14: 91883672-
Island







91885367


cg19513004
chr6: 34206683
HMGA1.UTR5
SCLC-A
F
chr6: 34202567-
S_Shore







34206193


cg20217702
chr3: 134094099
AMOTL2.TSS1500
SCLC-A
F
chr3: 134092257-
S_Shore







134093741


cg21279806
chr6: 169654719
THBS2.TSS1500
SCLC-A
R


cg22017213
chr4: 86851225
ARHGAP24.GENEBODY
SCLC-A
F


cg22231602
chr1: 241176676
RGS7.GENEBODY
SCLC-A
F


cg23358740
chr14: 102198157
C14orf72.GENEBODY
SCLC-A
R


cg27096172
chr7: 158350433
PTPRN2.GENEBODY
SCLC-A
R
chr7: 158349387-
S_Shore







158350091


cg00590039
chr6: 111888683
TRAF3IP2.GENEBODY
SCLC-A
F


cg03653855
chr5: 146436093
PPP2R2B.UTR5
SCLC-A
R


cg03775459
chr7: 105278448
ATXN7L1.GENEBODY
SCLC-A
R


cg07602073
chr1: 228595680
TRIM17.UTR3
SCLC-A
F
chr1: 228593811-
S_Shore







228594713


cg09682426
chr6: 168901167
SMOC2.GENEBODY
SCLC-A
F


cg10896862
chr1: 161275561
MPZ.UTR3
SCLC-A
R


cg11534680
chr2: 11680020
GREB1.UTR5
SCLC-A
R


cg14666310
chr19: 42211479
CEACAM5.TSS1500
SCLC-A
F


cg16748524
chr7: 157568392
PTPRN2.GENEBODY
SCLC-A
F
chr7: 157568163-
Island







157568404


cg22539431
chr7: 127423253
SND1.GENEBODY
SCLC-A
R


cg23447239
chr7: 157697628
PTPRN2.GENEBODY
SCLC-A
F
chr7: 157694387-
S_Shelf







157694661


cg24996491
chr7: 157535296
PTPRN2.GENEBODY
SCLC-A
R


cg01259220
chr7: 914964
C7orf20.TSS1500
SCLC-A
F
chr7: 915753-916644
N_Shore


cg01625621
chr15: 34260433
AVEN.GENEBODY
SCLC-A
R


cg02671204
chr16: 84076834
SLC38A8.TSS1500
SCLC-A
F


cg03512414
chr20: 19915874
RIN2.GENEBODY
SCLC-A
R


cg04982488
chr10: 116103698
AFAP1L2.GENEBODY
SCLC-A
F


cg06612016
chr7: 158113184
PTPRN2.GENEBODY
SCLC-A
R
chr7: 158109334-
S_Shelf







158109594


cg07543823
chr22: 20254968
RTN4R.GENEBODY
SCLC-A
R
chr22: 20254889-
Island







20255692


cg09985802
chr10: 126234119
LHPP.GENEBODY
SCLC-A
R


cg12057576
chr15: 78918529
CHRNB4.GENEBODY
SCLC-A
R


cg12492087
chr15: 42749885
ZFP106.TSS200
SCLC-A
F


cg17772793
chr6: 168901202
SMOC2.GENEBODY
SCLC-A
R


cg19681352
chr1: 27282675
C1orf172.UTR5
SCLC-A
R
chr1: 27286065-
N_Shelf







27287101


cg23312425
chr11: 64120623
CCDC88B.GENEBODY
SCLC-A
F


cg25513853
chr17: 72272298
DNAI2.UTR5
SCLC-A
F
chr17: 72270301-
S_Shore







72270512


cg01312997
chr2: 128180646
PROC.GENEBODY
SCLC-A
R
chr2: 128180294-
Island







128181381


cg02641539
chr8: 105351190
TM7SF4.TSS1500
SCLC-A
R


cg04432875
chr13: 113411561
ATP11A.GENEBODY
SCLC-A
R
chr13: 113410004-
S_Shore







113410362


cg06626786
chr21: 36094858
NCRNA00160.TSS1500
SCLC-A
R


cg06977987
chr11: 4902464
OR51T1.TSS1500
SCLC-A
R


cg07926178
chr7: 158130463
PTPRN2.GENEBODY
SCLC-A
R


cg09001440
chr16: 87952767
CASA.GENEBODY
SCLC-A
F


cg10926554
chr6: 111888540
TRAF3IP2.GENEBODY
SCLC-A
R


cg11863717
chr10: 73725041
CHST3.UTR5
SCLC-A
R
chr10: 73723711-
S_Shore







73724770


cg12109740
chr11: 72084034
CLPB.GENEBODY
SCLC-A
R


cg13427810
chr9: 116990636
COL27A1.GENEBODY
SCLC-A
F


cg23234179
chr12: 88420834
C12orf50.UTR5
SCLC-A
R


cg23520574
chr11: 4928572
OR51A7.TSS200
SCLC-A
R


cg24500959
chr10: 99474813
MARVELD1.GENEBODY
SCLC-A
R
chr10: 99473084-
S_Shore







99473291


cg21756355
chr7: 2233135
MAD1L1.GENEBODY
SCLC-A
F


cg00794178
chr3: 182897283
MCF2L2.GENEBODY
SCLC-A
F
chr3: 182896920-
Island







182897381


cg04336561
chr7: 157548939
PTPRN2.GENEBODY
SCLC-A
F
chr7: 157550547-
N_Shore







157551025


cg05064223
chr7: 157611269
PTPRN2.GENEBODY
SCLC-A
R
chr7: 157612036-
N_Shore







157612316


cg07047280
chr21: 41516394
DSCAM.GENEBODY
SCLC-A
F
chr21: 41516237-
Island







41516472


cg07099407
chr6: 43027930
KLC4.TSS1500
SCLC-A
R
chr6: 43026939-
S_Shore







43027841


cg07576632
chr6: 168844079
SMOC2.GENEBODY
SCLC-A
R
chr6: 168841818-
S_Shore







168843100


cg07865091
chr1: 43814306
MPL.GENEBODY
SCLC-A
R
chr1: 43814305-
Island







43815277


cg11528849
chr2: 182542901
NEUROD1.GENEBODY
SCLC-A
R


cg12510724
chr12: 6484607
SCNN1A.GENEBODY
SCLC-A
F


cg13049992
chr5: 125800778
GRAMD3.GENEBODY
SCLC-A
F


cg17027260
chr2: 109892050
SH3RF3.GENEBODY
SCLC-A
R


cg19713567
chr17: 37895429
GRB7.UTR5
SCLC-A
F


cg21850830
chr8: 124553593
FBXO32.TSS200
SCLC-A
R
chr8: 124552539-
Island







124554017


cg22139166
chr5: 124071107
ZNF608.GENEBODY
SCLC-A
F


cg22211507
chr3: 108564871
TRAT1.GENEBODY
SCLC-A
F


cg22676000
chr19: 42259081
CEACAM6.TSS1500
SCLC-A
F


cg22862420
chr6: 153368919
RGS17.UTR5
SCLC-A
R


cg25098281
chr12: 6484713
SCNN1A.GENEBODY
SCLC-A
F


cg25735076
chr7: 158157881
PTPRN2.GENEBODY
SCLC-A
R


cg26265390
chr6: 168867606
SMOC2.GENEBODY
SCLC-A
F


cg26308909
chr7: 2233090
MAD1L1.GENEBODY
SCLC-A
F


cg12487162
chr11: 12845864
TEAD1.GENEBODY
SCLC-A
R


cg00467296
chr11: 4928760
OR51A7.EXON1
SCLC-A
R


cg00751271
chr21: 36095899
NCRNA00160.TSS1500
SCLC-A
R


cg02964356
chr12: 49883750
SPATS2.GENEBODY
SCLC-A
R


cg03521982
chr18: 70206471
CBLN2.GENEBODY
SCLC-A
F
chr18: 70208974-
N_Shelf







70211790


cg05004506
chr11: 4945422
OR51G1.EXON1
SCLC-A
F


cg07157169
chr5: 126984994
CTXN3.EXON1
SCLC-A
F


cg08867933
chr15: 89150842
MIR1179.TSS1500
SCLC-A
F
chr15: 89147660-
S_Shore







89149198


cg11686009
chr20: 2305747
TGM3.GENEBODY
SCLC-A
R
chr20: 2308778-2309042
N_Shelf


cg12812834
chr11: 4870255
OR51S1.EXON1
SCLC-A
F


cg13464573
chr2: 7172097
RNF144A.GENEBODY
SCLC-A
F
chr2: 7172296-7172512
N_Shore


cg16826777
chr17: 43376882
MAP3K14.UTR5
SCLC-A
F


cg17898069
chr1: 234445489
SLC35F3.GENEBODY
SCLC-A
F


cg18705776
chr10: 5565829
CALML3.TSS1500
SCLC-A
R
chr10: 5567122-5567828
N_Shore


cg20235871
chr7: 158047359
PTPRN2.GENEBODY
SCLC-A
F


cg20444218
chr11: 73024037
ARHGEF17.GENEBODY
SCLC-A
F
chr11: 73018452-
S_Shelf







73020563


cg20786131
chr18: 20714496
CABLES1.TSS1500
SCLC-A
F
chr18: 20714968-
N_Shore







20717071


cg23181133
chr19: 42300812
CEACAM3.GENEBODY
SCLC-A
F


cg26169081
chr10: 12648338
CAMK1D.GENEBODY
SCLC-A
R


cg26430059
chr14: 89770384
FOXN3.GENEBODY
SCLC-A
R


cg00172803
chr16: 84076941
SLC38A8.TSS1500
SCLC-A
R


cg00832555
chr3: 169529716
LRRC34.GENEBODY
SCLC-A
F
chr3: 169529875-
N_Shore







169530435


cg05214130
chr12: 123945990
SNRNP35.GENEBODY
SCLC-A
F
chr12: 123942639-
S_Shelf







123943001


cg06656027
chr12: 50016493
PRPF40B.TSS1500
SCLC-A
R
chr12: 50016973-
N_Shore







50017466


cg07160163
chr9: 93563778
SYK.TSS1500
SCLC-A
R
chr9: 93563775-
Island







93564546


cg08692006
chr19: 4639992
TNFAIP8L1.TSS200
SCLC-A
F
chr19: 4639218-4639750
S_Shore


cg11028923
chr5: 43557644
PAIP1.TSS1500
SCLC-A
R
chr5: 43556419-
S_Shore







43557603


cg12364943
chr10: 134108614
STK32C.GENEBODY
SCLC-A
F


cg12581598
chr1: 202537837
PPP1R12B.GENEBODY
SCLC-A
F


cg14199629
chr9: 84202866
TLE1.GENEBODY
SCLC-A
F


cg16063747
chr10: 119294173
EMX2OS.GENEBODY
SCLC-A
R
chr10: 119293917-
Island







119297675


cg20443278
chr17: 77962098
TBC1D16.GENEBODY
SCLC-A
R
chr17: 77965805-
N_Shelf







77966296


cg21436938
chr9: 116061416
RNF183.TSS200
SCLC-A
F


cg23235971
chr7: 157413057
PTPRN2.GENEBODY
SCLC-A
F
chr7: 157413901-
N_Shore







157414146


cg23361275
chr8: 8749919
MFHAS1.EXON1
SCLC-A
R
chr8: 8748652-8751478
Island


cg24186774
chr14: 63757917
RHOJ.UTR3
SCLC-A
F


cg25223634
chr10: 104536695
C10orf26.GENEBODY
SCLC-A
R


cg00283524
chr22: 44639906
KIAA1644.UTR3
SCLC-A
F


cg01582616
chr7: 157595153
PTPRN2.GENEBODY
SCLC-A
R
chr7: 157593887-
S_Shore







157594128


cg04593696
chr16: 84076900
SLC38A8.TSS1500
SCLC-A
F


cg05233289
chr11: 64120728
CCDC88B.GENEBODY
SCLC-A
R


cg06721096
chr7: 157336864
PTPRN2.GENEBODY
SCLC-A
F


cg08006727
chr9: 116061614
RNF183.TSS1500
SCLC-A
R


cg10173620
chr15: 89658904
ABHD2.UTR5
SCLC-A
R


cg12551557
chr12: 32308125
BICD1.GENEBODY
SCLC-A
R


cg14638988
chr11: 62476544
BSCL2.TSS1500
SCLC-A
F
chr11: 62476770-
N_Shore







62477481


cg16288617
chr8: 61190272
CA8.GENEBODY
SCLC-A
F
chr8: 61193312-
N_Shelf







61194195


cg16347213
chr21: 42687940
FAM3B.TSS1500
SCLC-A
F
chr21: 42688746-
N_Shore







42689085


cg17801546
chr1: 167090974
DUSP27.GENEBODY
SCLC-A
R
chr1: 167090575-
Island







167091010


cg19434087
chr7: 157696664
PTPRN2.GENEBODY
SCLC-A
F
chr7: 157695025-
S_Shore







157695358


cg22797514
chr1: 44016023
PTPRF.GENEBODY
SCLC-A
F


cg23632744
chr11: 4674353
OR51E1.GENEBODY
SCLC-A
R


cg24575128
chr3: 52502445
NISCH.GENEBODY
SCLC-A
R


cg25641451
chr11: 4976263
OR51A2.EXON1
SCLC-A
F


cg00648955
chr2: 31456217
EHD3.TSS1500
SCLC-A
R
chr2: 31456740-
N_Shore







31457653


cg01759986
chr20: 22401074
LOC284788.GENEBODY
SCLC-A
F


cg06683080
chr15: 40646549
PHGR1.GENEBODY
SCLC-A
R
chr15: 40650055-
N_Shelf







40651102


cg08339915
chr7: 157394582
PTPRN2.GENEBODY
SCLC-A
F


cg08356705
chr11: 68148006
LRP5.GENEBODY
SCLC-A
R


cg09833475
chr7: 157463804
PTPRN2.GENEBODY
SCLC-A
R


cg14583225
chr17: 40074010
ACLY.UTR5
SCLC-A
R
chr17: 40074291-
N_Shore







40075380


cg15331500
chr22: 41779351
TEF.GENEBODY
SCLC-A
F
chr22: 41777430-
S_Shore







41778281


cg19138905
chr11: 4902583
OR51T1.TSS1500
SCLC-A
R


cg20083900
chr7: 157624841
PTPRN2.GENEBODY
SCLC-A
F


cg20984904
chr7: 157529335
PTPRN2.GENEBODY
SCLC-A
R
chr7: 157524157-
S_Shelf







157526741


cg21602520
chr18: 60985380
BCL2.GENEBODY
SCLC-A
F
chr18: 60985503-
N_Shore







60985741


cg24939194
chr7: 2563611
LFNG.GENEBODY
SCLC-A
R
chr7: 2563610-2564056
Island


cg26434090
chr11: 117665395
DSCAML1.GENEBODY
SCLC-A
R
chr11: 117666634-
N_Shore







117668141


cg00833703
chr16: 57809842
KIFC3.GENEBODY
SCLC-A
R


cg03916382
chr7: 157935049
PTPRN2.GENEBODY
SCLC-A
R
chr7: 157937614-
N_Shelf







157937841


cg04057488
chr6: 168920227
SMOC2.GENEBODY
SCLC-A
R
chr6: 168918596-
S_Shore







168918902


cg05310309
chr2: 109257429
LIMS1.UTR5
SCLC-A
F


cg06649856
chr7: 158355003
PTPRN2.GENEBODY
SCLC-A
R


cg09230014
chr7: 157876369
PTPRN2.GENEBODY
SCLC-A
F


cg10178498
chr3: 124103021
KALRN.GENEBODY
SCLC-A
F


cg11374256
chr8: 144888445
SCRIB.GENEBODY
SCLC-A
R
chr8: 144887111-
S_Shore







144887662


cg13393785
chr19: 8317932
LASS4.GENEBODY
SCLC-A
R


cg18406801
chr2: 109294820
LIMS1.GENEBODY
SCLC-A
F


cg22297710
chr8: 79717861
IL7.TSS200
SCLC-A
F
chr8: 79716681-
S_Shore







79717403


cg24248505
chr7: 105279790
ATXN7L1.GENEBODY
SCLC-A
R


cg24938166
chr2: 70941682
ADD2.UTR5
SCLC-A
R


cg26396492
chr20: 19915762
RIN2.GENEBODY
SCLC-A
R


cg09279037
chr7: 158103293
PTPRN2.GENEBODY
SCLC-A
F
chr7: 158103336-
N_Shore







158103601


cg16284674
chr10: 135123337
ZNF511.GENEBODY
SCLC-A
F
chr10: 135123238-
Island







135123448


cg01089425
chr5: 10655518
ANKRD33B.UTR3
SCLC-A
R


cg03315058
chr11: 62476542
BSCL2.TSS1500
SCLC-A
F
chr11: 62476770-
N_Shore







62477481


cg04713531
chr7: 158197288
PTPRN2.GENEBODY
SCLC-A
F
chr7: 158198545-
N_Shore







158198907


cg07285983
chr1: 174844490
RABGAP1L.GENEBODY
SCLC-A
F


cg10188797
chr17: 77962048
TBC1D16.GENEBODY
SCLC-A
F
chr17: 77965805-
N_Shelf







77966296


cg10825530
chr11: 16023708
SOX6.GENEBODY
SCLC-A
R


cg13685679
chr17: 79231688
SLC38A10.GENEBODY
SCLC-A
F
chr17: 79235486-
N_Shelf







79235751


cg22209929
chr3: 172394700
NCEH1.UTR5
SCLC-A
R


cg23735602
chr3: 178276672
KCNMB2.UTR5
SCLC-A
R


cg24153714
chr10: 78057958
C10orf11.GENEBODY
SCLC-A
F


cg24576995
chr7: 157854008
PTPRN2.GENEBODY
SCLC-A
F


cg24813588
chr20: 62606499
SAMD10.UTR3
SCLC-A
R
chr20: 62605261-
S_Shore







62605463


cg26967186
chr7: 157919649
PTPRN2.GENEBODY
SCLC-A
F
chr7: 157918704-
S_Shore







157919409


cg01610165
chr5: 124071029
ZNF608.GENEBODY
SCLC-A
R


cg01083884
chr13: 113641411
MCF2L.GENEBODY
SCLC-A
R


cg08102294
chr3: 13063918
IQSEC1.GENEBODY
SCLC-A
F


cg08648047
chr1: 11028561
C1orf127.GENEBODY
SCLC-A
F


cg09337391
chr20: 45871363
ZMYND8.GENEBODY
SCLC-A
R
chr20: 45867654-
S_Shelf







45868111


cg10761558
chr1: 54842205
SSBP3.GENEBODY
SCLC-A
F


cg11747695
chr13: 111164966
COL4A2.UTR3
SCLC-A
F
chr13: 111164284-
S_Shore







111164547


cg12019520
chr4: 8012176
ABLIM2.GENEBODY
SCLC-A
F


cg15061647
chr7: 158249209
PTPRN2.GENEBODY
SCLC-A
F
chr7: 158247888-
Island







158249312


cg17658976
chr7: 158111178
PTPRN2.GENEBODY
SCLC-A
F
chr7: 158109334-
S_Shore







158109594


cg22021832
chr19: 42944717
CXCL17.GENEBODY
SCLC-A
R


cg24283093
chr3: 14481550
SLC6A6.UTR5
SCLC-A
F


cg25291404
chr20: 30252580
BCL2L1.UTR3
SCLC-A
R


cg27096807
chr3: 111442336
PLCXD2.UTR3
SCLC-A
R


cg10095968
chr21: 45847903
TRPM2.GENEBODY
SCLC-A
R
chr21: 45844992-
S_Shelf







45845693


cg15691129
chrX: 68725815
FAM155B.EXON1
SCLC-A
R
chrX: 68723731-
Island







68726051


cg23631070
chrX: 17652804
NHS.TSS1500
SCLC-A
R


cg00254714
chr20: 2309923
TGM3.GENEBODY
SCLC-A
R
chr20: 2308778-2309042
S_Shore


cg02624246
chr12: 7073264
MIR141.GENEBODY
SCLC-A
F


cg03079132
chr16: 727212
RHBDL1.GENEBODY
SCLC-A
R
chr16: 729438-735815
N_Shelf


cg05195085
chr7: 157951403
PTPRN2.GENEBODY
SCLC-A
F
chr7: 157951254-
Island







157951800


cg05308556
chr7: 157408770
PTPRN2.GENEBODY
SCLC-A
F
chr7: 157409846-
N_Shore







157410241


cg06164804
chr2: 240044389
HDAC4.GENEBODY
SCLC-A
R
chr2: 240046200-
N_Shore







240046736


cg06675455
chr11: 4902491
OR51T1.TSS1500
SCLC-A
R


cg09958065
chr10: 12648526
CAMK1D.GENEBODY
SCLC-A
R


cg10249637
chr7: 157655436
PTPRN2.GENEBODY
SCLC-A
F
chr7: 157659433-
N_Shelf







157660322


cg10999000
chr13: 111180025
RAB20.GENEBODY
SCLC-A
F


cg11161846
chr1: 160990452
F11R.GENEBODY
SCLC-A
R
chr1: 160990718-
N_Shore







160991225


cg11859489
chr15: 92459058
SLCO3A1.GENEBODY
SCLC-A
F
chr15: 92459266-
N_Shore







92459678


cg12817840
chr5: 124070989
ZNF608.GENEBODY
SCLC-A
F


cg16964025
chr7: 157482215
PTPRN2.GENEBODY
SCLC-A
F
chr7: 157476886-
Island







157486719


cg19404444
chr1: 2164602
SKI.GENEBODY
SCLC-A
R
chr1: 2158212-2161173
S_Shelf


cg22531685
chr7: 158264663
PTPRN2.GENEBODY
SCLC-A
R


cg25003275
chr4: 7940128
AFAP1.UTR5
SCLC-A
F
chr4: 7940563-7941853
N_Shore


cg25541259
chr2: 230576135
DNER.GENEBODY
SCLC-A
R
chr2: 230578062-
N_Shore







230579981


cg00866953
chr1: 15417078
KIAA1026.GENEBODY
SCLC-A
F


cg01315919
chr20: 22401404
LOC284788.TSS200
SCLC-A
F


cg08705382
chr1: 230322024
GALNT2.GENEBODY
SCLC-A
F


cg15572489
chr7: 157481091
PTPRN2.GENEBODY
SCLC-A
R
chr7: 157476886-
Island







157486719


cg21759331
chr2: 209352598
PTH2R.GENEBODY
SCLC-A
R


cg05439204
chr7: 157854693
PTPRN2.GENEBODY
SCLC-A
F


cg08240778
chr11: 1643787
HCCA2.GENEBODY
SCLC-A
F


cg08515811
chr17: 77921489
TBC1D16.GENEBODY
SCLC-A
R
chr17: 77922721-
N_Shore







77922973


cg08845722
chr2: 46041801
PRKCE.GENEBODY
SCLC-A
F


cg09314984
chr19: 5627625
SAFB.GENEBODY
SCLC-A
R
chr19: 5622248-5623712
S_Shelf


cg09353345
chr15: 78918560
CHRNB4.GENEBODY
SCLC-A
R


cg10520790
chr4: 16030846
PROM1.GENEBODY
SCLC-A
R


cg14157855
chr1: 32226424
BAI2.UTR5
SCLC-A
R
chr1: 32226146-
Island







32226535


cg16717192
chr7: 4265800
SDK1.GENEBODY
SCLC-A
R


cg19307500
chr19: 1083193
HMHA1.GENEBODY
SCLC-A
R
chr19: 1082576-1083430
Island


cg21660130
chr1: 16370243
CLCNKB.TSS200
SCLC-A
R


cg22531371
chr1: 155162756
MUC1.TSS200
SCLC-A
F
chr1: 155163434-
N_Shore







155163818


cg02690968
chr11: 35683923
TRIM44.TSS1500
SCLC-A
F
chr11: 35684421-
N_Shore







35684846


cg03337035
chr19: 42258336
CEACAM6.TSS1500
SCLC-A
R


cg03694261
chr11: 122753977
C11orf63.UTR5
SCLC-A
F
chr11: 122753386-
S_Shore







122753951


cg04701181
chr11: 1606344
HCCA2.GENEBODY
SCLC-A
F


cg05327192
chr11: 75133593
KLHL35.UTR3
SCLC-A
F
chr11: 75136407-
N_Shelf







75136689


cg06294561
chr3: 141161580
ZBTB38.GENEBODY
SCLC-A
F


cg12149911
chr8: 61194292
CA8.TSS1500
SCLC-A
R
chr8: 61193312-
S_Shore







61194195


cg14651919
chr17: 74075189
ZACN.TSS200
SCLC-A
R
chr17: 74070404-
S_Shore







74073530


cg15221831
chr19: 42408464
ARHGEF1.GENEBODY
SCLC-A
F
chr19: 42408315-
Island







42408535


cg16537859
chrX: 70440209
BCYRN1.GENEBODY
SCLC-A
F
chrX: 70444046-
N_Shelf







70444270


cg22544881
chr7: 130712346
FLJ43663.GENEBODY
SCLC-A
R


cg24178676
chr5: 172264981
ERGIC1.GENEBODY
SCLC-A
F
chr5: 172261145-
S_Shelf







172261671


cg25205321
chr13: 111096339
COL4A2.GENEBODY
SCLC-A
R


cg00234370
chr1: 36021674
KIAA0319L.UTR5
SCLC-A
F
chr1: 36022680-
N_Shore







36023834


cg00806680
chr6: 41561085
FOXP4.GENEBODY
SCLC-A
F
chr6: 41561221-
N_Shore







41561473


cg06716730
chr17: 35851459
DUSP14.UTR5
SCLC-A
R
chr17: 35849290-
S_Shore







35850483


cg21521989
chr7: 158269194
PTPRN2.GENEBODY
SCLC-A
F


cg02855558
chr7: 158107723
PTPRN2.GENEBODY
SCLC-A
F
chr7: 158109334-
N_Shore







158109594


cg04204246
chr6: 112537238
LAMA4.GENEBODY
SCLC-A
R


cg05087455
chr2: 7171869
RNF144A.GENEBODY
SCLC-A
R
chr2: 7172296-7172512
N_Shore


cg05295557
chr14: 36988446
NKX2-1.GENEBODY
SCLC-A
F
chr14: 36986362-
Island







36990576


cg05913555
chr7: 158158760
PTPRN2.GENEBODY
SCLC-A
R


cg11938455
chr6: 15622032
DTNBP1.GENEBODY
SCLC-A
R


cg13417891
chr17: 35836996
TADA2A.GENEBODY
SCLC-A
F


cg14672994
chr17: 48503057
ACSF2.TSS1500
SCLC-A
R
chr17: 48503056-
Island







48503887


cg20313969
chr2: 112939562
FBLN7.GENEBODY
SCLC-A
F
chr2: 112939287-
Island







112939563


cg23540651
chr1: 89490034
GBP3.TSS1500
SCLC-A
R


cg24611996
chr10: 120353499
PRLHR.UTR3
SCLC-A
R
chr10: 120353692-
N_Shore







120355821


cg00735611
chr17: 37895886
GRB7.UTR5
SCLC-A
R


cg04645676
chr5: 10655569
ANKRD33B.UTR3
SCLC-A
F


cg04854917
chr10: 131378330
MGMT.GENEBODY
SCLC-A
R


cg09149842
chr20: 31351091
DNMT3B.UTR5
SCLC-A
R
chr20: 31350149-
Island







31351263


cg13167816
chr14: 24601808
FITM1.GENEBODY
SCLC-A
F
chr14: 24601498-
S_Shore







24601700


cg14753321
chr5: 176784914
RGS14.UTR5
SCLC-A
F


cg15736062
chr7: 158136485
PTPRN2.GENEBODY
SCLC-A
R


cg15978565
chr2: 11894464
LPIN1.UTR5
SCLC-A
R


cg16427983
chr12: 123453858
ABCB9.UTR5
SCLC-A
F
chr12: 123450868-
S_Shelf







123451207


cg16809526
chr16: 46917681
GPT2.TSS1500
SCLC-A
F
chr16: 46917849-
N_Shore







46918957


cg17019292
chr5: 68710813
MARVELD2.TSS200
SCLC-A
R
chr5: 68710807-
Island







68711520


cg27270684
chr7: 55757158
FKBP9L.TSS200
SCLC-A
R


cg27470486
chr17: 40073688
ACLY.UTR5
SCLC-A
F
chr17: 40074291-
N_Shore







40075380


cg02711212
chr15: 69854024
LOC145837.TSS200
SCLC-A
F


cg04810063
chr16: 88703634
IL17C.TSS1500
SCLC-A
F
chr16: 88706211-
N_Shelf







88706492


cg06313349
chr7: 157494424
PTPRN2.GENEBODY
SCLC-A
R
chr7: 157494510-
N_Shore







157494739


cg11577716
chr20: 20258001
C20orf26.GENEBODY
SCLC-A
F


cg12144100
chr7: 157890277
PTPRN2.GENEBODY
SCLC-A
R
chr7: 157890656-
N_Shore







157891557


cg14689490
chr7: 158210489
PTPRN2.GENEBODY
SCLC-A
R


cg17959824
chr11: 70391706
SHANK2.GENEBODY
SCLC-A
F


cg21781706
chr1: 6438350
ACOT7.GENEBODY
SCLC-A
F


cg24634333
chr6: 111887834
TRAF3IP2.GENEBODY
SCLC-A
R


cg06520307
chr7: 149417640
KRBA1.GENEBODY
SCLC-A
F
chr7: 149416662-
S_Shore







149416974


cg07780818
chr3: 133749284
SLCO2A1.TSS1500
SCLC-A
R
chr3: 133747920-
S_Shore







133748266


cg07790176
chr13: 92601293
GPC5.GENEBODY
SCLC-A
R


cg09635395
chr4: 146601470
C4orf51.EXON1
SCLC-A
F


cg14497491
chr17: 77982477
TBC1D16.GENEBODY
SCLC-A
F
chr17: 77983980-
N_Shore







77984482


cg15318176
chr7: 157345827
PTPRN2.GENEBODY
SCLC-A
F
chr7: 157346613-
N_Shore







157347069


cg16792062
chr11: 128458153
ETS1.TSS1500
SCLC-A
R


cg17602451
chr18: 60985645
BCL2.GENEBODY
SCLC-A
R
chr18: 60985503-
Island







60985741


cg19628299
chr6: 168840641
SMOC2.TSS1500
SCLC-A
F
chr6: 168841438-
N_Shore







168841699


cg20731121
chr3: 111636305
PHLDB2.GENEBODY
SCLC-A
F


cg25871713
chr3: 37823949
ITGA9.GENEBODY
SCLC-A
R


cg26924822
chr4: 26332763
RBPJ.GENEBODY
SCLC-A
F


cg00542975
chr2: 122392291
CLASP1.UTR5
SCLC-A
R


cg01961752
chr1: 1109012
TTLL10.TSS1500
SCLC-A
R
chr1: 1109314-1110145
N_Shore


cg02369113
chr7: 157637560
PTPRN2.GENEBODY
SCLC-A
R


cg03486974
chr16: 2199702
RAB26.GENEBODY
SCLC-A
R
chr16: 2198455-2199129
S_Shore


cg03767531
chr2: 182545572
NEUROD1.TSS200
SCLC-A
F
chr2: 182547873-
N_Shelf







182549177


cg04143211
chr14: 91087927
TTC7B.GENEBODY
SCLC-A
R
chr14: 91087475-
S_Shore







91087796


cg04489012
chr1: 151812710
LOC100132111.GENEBODY
SCLC-A
F
chr1: 151810460-
S_Shore







151811684


cg05942111
chr12: 65044027
RASSF3.GENEBODY
SCLC-A
R


cg06497408
chr7: 158046838
PTPRN2.GENEBODY
SCLC-A
F


cg07243405
chr7: 915203
C7orf20.TSS1500
SCLC-A
R
chr7: 915753-916644
N_Shore


cg15490801
chr14: 30054523
PRKD1.GENEBODY
SCLC-A
F


cg17316096
chr7: 158158218
PTPRN2.GENEBODY
SCLC-A
R


cg18470891
chr12: 2986957
FOXM1.TSS1500
SCLC-A
R
chr12: 2985978-2986639
S_Shore


cg21790851
chr13: 73634643
KLF5.GENEBODY
SCLC-A
F
chr13: 73632860-
S_Shore







73634370


cg24580076
chr7: 915073
C7orf20.TSS1500
SCLC-A
F
chr7: 915753-916644
N_Shore


cg25727520
chr2: 37576821
QPCT.GENEBODY
SCLC-A
R


cg26003056
chr5: 89908195
GPR98.GENEBODY
SCLC-A
F


cg26231267
chr10: 12648032
CAMK1D.GENEBODY
SCLC-A
R


cg00072720
chr17: 7165831
CLDN7.TSS200
SCLC-A
R
chr17: 7164285-7166245
Island


cg02364642
chr12: 58005758
GEFT.EXON1
SCLC-A
R
chr12: 58003880-
S_Shore







58004249


cg02643580
chr12: 95671146
VEZT.GENEBODY
SCLC-A
R


cg02836529
chr2: 182544413
NEUROD1.UTR5
SCLC-A
R
chr2: 182547873-
N_Shelf







182549177


cg03641492
chr6: 168859954
SMOC2.GENEBODY
SCLC-A
R


cg04048740
chr2: 236442999
AGAP1.GENEBODY
SCLC-A
F
chr2: 236443815-
N_Shore







236444025


cg04162999
chr11: 64120313
CCDC88B.GENEBODY
SCLC-A
R


cg06400336
chr8: 103136701
NCALD.TSS200
SCLC-A
R
chr8: 103135914-
Island







103136775


cg10198932
chr21: 43136287
C21orf129.TSS1500
SCLC-A
F


cg10308629
chr7: 134354803
BPGM.GENEBODY
SCLC-A
R


cg12813108
chr7: 99719912
CNPY4.GENEBODY
SCLC-A
R


cg15906675
chr4: 90171420
GPRIN3.UTR5
SCLC-A
R


cg17093877
chr17: 72206412
MGC16275.GENEBODY
SCLC-A
F
chr17: 72208474-
N_Shelf







72208902


cg18214661
chr8: 17471997
PDGFRL.GENEBODY
SCLC-A
R


cg00279797
chrX: 109561918
AMMECR1.UTR5
SCLC-A
R
chrX: 109560703-
S_Shore







109561534


cg01138652
chr22: 19973978
ARVCF.GENEBODY
SCLC-A
F
chr22: 19974274-
N_Shore







19974756


cg04457354
chr6: 20447442
E2F3.GENEBODY
SCLC-A
F


cg05564438
chr11: 64120286
CCDC88B.GENEBODY
SCLC-A
R


cg07120097
chr14: 37257605
SLC25A21.GENEBODY
SCLC-A
R


cg14362920
chr7: 157332376
PTPRN2.UTR3
SCLC-A
R


cg21763058
chr12: 49740976
DNAJC22.TSS200
SCLC-A
R
chr12: 49738680-
S_Shore







49740841


cg22193393
chr15: 42290845
PLA2G4E.GENEBODY
SCLC-A
R


cg23392097
chr11: 4704749
OR51E2.UTR5
SCLC-A
R


cg26379258
chr6: 111888446
TRAF3IP2.GENEBODY
SCLC-A
R


cg02753354
chr19: 1074727
HMHA1.GENEBODY
SCLC-A
R
chr19: 1074726-1075071
Island


cg04531425
chr2: 182322841
ITGA4.GENEBODY
SCLC-A
F
chr2: 182321761-
Island







182323029


cg04955511
chr7: 14801527
DGKB.GENEBODY
SCLC-A
F


cg05093113
chr20: 49200925
MIR645.TSS1500
SCLC-A
F


cg06979020
chr16: 69660388
NFAT5.UTR5
SCLC-A
R


cg07756135
chr4: 86748944
ARHGAP24.GENEBODY
SCLC-A
F


cg09832443
chr7: 28612680
CREB5.GENEBODY
SCLC-A
F


cg13464117
chr7: 157348161
PTPRN2.GENEBODY
SCLC-A
R
chr7: 157346613-
S_Shore







157347069


cg14141549
chr7: 157919408
PTPRN2.GENEBODY
SCLC-A
F
chr7: 157918704-
Island







157919409


cg15353612
chr4: 52904965
SGCB.TSS1500
SCLC-A
F
chr4: 52904454-
S_Shore







52904912


cg20978600
chr3: 40566157
ZNF621.TSS1500
SCLC-A
R
chr3: 40566129-
Island







40566689


cg21191737
chr9: 15306337
TTC39B.GENEBODY
SCLC-A
F
chr9: 15306722-
N_Shore







15307386


cg23574281
chr2: 47716
FAM110C.TSS1500
SCLC-A
R
chr2: 45510-46559
S_Shore


cg00459232
chr12: 6309025
CD9.TSS1500
SCLC-A
R
chr12: 6309152-6310392
N_Shore


cg02479744
chr6: 16303089
ATXN1.UTR3
SCLC-A
R


cg02735652
chr1: 32226179
BAI2.UTR5
SCLC-A
R
chr1: 32226146-
Island







32226535


cg05175762
chr7: 157987088
PTPRN2.GENEBODY
SCLC-A
F


cg05722741
chr6: 168897588
SMOC2.GENEBODY
SCLC-A
F


cg08134671
chr19: 2542837
GNG7.UTR5
SCLC-A
R
chr19: 2543638-2543878
N_Shore


cg09614629
chr7: 157985057
PTPRN2.GENEBODY
SCLC-A
R
chr7: 157980786-
S_Shelf







157981462


cg10536786
chr1: 7550036
CAMTA1.GENEBODY
SCLC-A
R


cg10754395
chr7: 158109694
PTPRN2.GENEBODY
SCLC-A
F
chr7: 158110569-
N_Shore







158110881


cg11980090
chr6: 30181771
TRIM26.TSS1500
SCLC-A
R
chr6: 30180933-
Island







30182187


cg12419766
chr7: 157620445
PTPRN2.GENEBODY
SCLC-A
R
chr7: 157618856-
S_Shore







157619302


cg12882572
chr17: 35851204
DUSP14.UTR5
SCLC-A
R
chr17: 35849290-
S_Shore







35850483


cg18822036
chr8: 131371659
ASAP1.GENEBODY
SCLC-A
R
chr8: 131370087-
S_Shore







131371317


cg20535931
chr7: 97615658
OCM2.GENEBODY
SCLC-A
F


cg22356339
chr12: 103352454
ASCL1.EXON1
SCLC-A
R
chr12: 103351579-
Island







103352695


cg26085804
chr11: 72854242
FCHSD2.TSS1500
SCLC-A
F
chr11: 72852176-
S_Shore







72854160


cg27567922
chr3: 195480636
MUC4.GENEBODY
SCLC-A
F
chr3: 195477711-
S_Shelf







195477983


cg00816406
chr1: 240286626
FMN2.GENEBODY
SCLC-A
F


cg01718785
chr7: 157916279
PTPRN2.GENEBODY
SCLC-A
F
chr7: 157918704-
N_Shelf







157919409


cg02601893
chr22: 43523016
BIK.GENEBODY
SCLC-A
F


cg13374528
chr7: 129414627
MIR96.TSS200
SCLC-A
R
chr7: 129418286-
N_Shelf







129422509


cg13689591
chr3: 124239629
KALRN.GENEBODY
SCLC-A
F


cg14575854
chr17: 37896175
GRB7.UTR5
SCLC-A
F


cg20208009
chr22: 19974048
ARVCF.GENEBODY
SCLC-A
F
chr22: 19974274-
N_Shore







19974756


cg26572392
chr10: 24496943
KIAA1217.UTR5
SCLC-A
R


cg26572992
chr19: 18876246
CRTC1.GENEBODY
SCLC-A
F
chr19: 18873019-
S_Shelf







18873349


cg26593067
chr7: 157446092
PTPRN2.GENEBODY
SCLC-A
R
chr7: 157448240-
N_Shelf







157448566


cg00325866
chr15: 62359130
C2CD4A.TSS200
SCLC-A
F
chr15: 62359827-
N_Shore







62360995


cg00690082
chr17: 40438511
STAT5A.TSS1500
SCLC-A
R
chr17: 40440188-
N_Shore







40441014


cg00929655
chr15: 92459909
SLCO3A1.GENEBODY
SCLC-A
R
chr15: 92459266-
S_Shore







92459678


cg01760027
chrX: 49832257
CLCN5.GENEBODY
SCLC-A
R


cg01983725
chr1: 227161799
CABC1.GENEBODY
SCLC-A
F
chr1: 227163739-
N_Shore







227164237


cg04868764
chr15: 41137019
SPINT1.GENEBODY
SCLC-A
F
chr15: 41135719-
Island







41137210


cg13700912
chr7: 1968348
MAD1L1.GENEBODY
SCLC-A
R
chr7: 1967664-1967994
S_Shore


cg14817241
chr19: 4851575
PLIN3.GENEBODY
SCLC-A
F
chr19: 4851962-4852248
N_Shore


cg16872071
chr9: 135997155
RALGDS.GENEBODY
SCLC-A
F
chr9: 135995969-
S_Shore







135996954


cg20867746
chr11: 4871813
OR51S1.TSS1500
SCLC-A
R


cg21376148
chr17: 10276260
MYH13.UTR5
SCLC-A
R


cg01352090
chr16: 4103533
ADCY9.GENEBODY
SCLC-A
F


cg01808739
chr1: 93912802
FNBP1L.TSS1500
SCLC-A
F
chr1: 93913636-
N_Shore







93914524


cg02058628
chr1: 2164542
SKI.GENEBODY
SCLC-A
F
chr1: 2158212-2161173
S_Shelf


cg07219844
chr10: 135123764
ZNF511.GENEBODY
SCLC-A
F
chr10: 135121991-
S_Shore







135122669


cg09526758
chr12: 16758047
LMO3.UTR5
SCLC-A
F


cg14507792
chr9: 95574913
ANKRD19.GENEBODY
SCLC-A
R
chr9: 95569429-
S_Shelf







95572255


cg16609181
chr19: 1083007
HMHA1.GENEBODY
SCLC-A
R
chr19: 1082576-1083430
Island


cg22337375
chr7: 157351042
PTPRN2.GENEBODY
SCLC-A
R
chr7: 157352995-
N_Shore







157353232


cg00926318
chr20: 25177340
ENTPD6.UTR5
SCLC-A
R
chr20: 25176027-
S_Shore







25176620


cg02051806
chr12: 86650107
MGAT4C.UTR5
SCLC-A
R


cg02051924
chr16: 11681482
LITAF.TSS200
SCLC-A
R
chr16: 11680008-
S_Shore







11681275


cg05767421
chr8: 120221185
MAL2.GENEBODY
SCLC-A
R
chr8: 120220388-
Island







120221222


cg06779248
chr7: 95458266
DYNC111.GENEBODY
SCLC-A
R


cg10709461
chr20: 22402729
LOC284788.TSS1500
SCLC-A
F


cg12379775
chr20: 62669791
NCRNA00176.GENEBODY
SCLC-A
F
chr20: 62669304-
Island







62670730


cg13265740
chr6: 139349120
C6orf115.TSS1500
SCLC-A
R
chr6: 139349955-
N_Shore







139350740


cg14192174
chr2: 29204117
FAM179A.TSS200
SCLC-A
F


cg18856478
chr1: 43814358
MPL.GENEBODY
SCLC-A
R
chr1: 43814305-
Island







43815277


cg20697464
chr2: 218793716
TNS1.UTR5
SCLC-A
R


cg23637314
chr1: 216774226
ESRRG.GENEBODY
SCLC-A
F
chr1: 216774339-
N_Shore







216774734


cg24728949
chr5: 106820169
EFNA5.GENEBODY
SCLC-A
F


cg26215113
chr2: 234369962
DGKD.GENEBODY
SCLC-A
R
chr2: 234369786-
Island







234370099


cg00008819
chr4: 3257791
C4orf44.UTR3
SCLC-A
F
chr4: 3254957-3255175
S_Shelf


cg00115178
chr10: 12648176
CAMK1D.GENEBODY
SCLC-A
R


cg02276086
chr2: 163175335
IFIH1.TSS1500
SCLC-A
F


cg02707152
chr11: 64980819
SLC22A20.TSS1500
SCLC-A
R


cg12538248
chr8: 61194072
CA8.TSS200
SCLC-A
R
chr8: 61193312-
Island







61194195


cg12806381
chr1: 27114177
PIGV.TSS1500
SCLC-A
F
chr1: 27114118-
Island







27114692


cg21292473
chr1: 181683239
CACNA1E.GENEBODY
SCLC-A
R


cg26392737
chr8: 21916853
EPB49.EXON1
SCLC-A
F
chr8: 21914275-
S_Shelf







21914525


cg00797278
chr3: 32442928
CMTM7.GENEBODY
SCLC-A
F
chr3: 32443152-
N_Shore







32443455


cg01435515
chr1: 151255742
ZNF687.UTR5
SCLC-A
R
chr1: 151253658-
Island







151255769


cg02710090
chr1: 207225128
PFKFB2.TSS1500
SCLC-A
F
chr1: 207226281-
N_Shore







207226842


cg04633683
chr16: 29837056
MVP.UTR5
SCLC-A
R


cg04905719
chr6: 134617250
SGK1.GENEBODY
SCLC-A
F


cg09035736
chr22: 38599166
MAFF.UTR5
SCLC-A
F
chr22: 38597785-
S_Shore







38598988


cg09556527
chr1: 1239259
ACAP3.GENEBODY
SCLC-A
F
chr1: 1242400-1245185
N_Shelf


cg11315900
chr7: 157605970
PTPRN2.GENEBODY
SCLC-A
R


cg22581896
chr7: 4779225
FOXK1.GENEBODY
SCLC-A
R


cg25124966
chr11: 129723987
TMEM45B.GENEBODY
SCLC-A
R


cg25718402
chr17: 7165909
CLDN7.TSS200
SCLC-A
F
chr17: 7164285-7166245
Island


cg02925076
chr7: 158251297
PTPRN2.GENEBODY
SCLC-A
F
chr7: 158247888-
S_Shore







158249312


cg05379127
chr19: 12885939
HOOK2.GENEBODY
SCLC-A
F
chr19: 12885756-
Island







12886519


cg09176256
chr10: 119293967
EMX2OS.GENEBODY
SCLC-A
F
chr10: 119293917-
Island







119297675


cg11944076
chr15: 51997390
SCG3.GENEBODY
SCLC-A
R


cg17519949
chr19: 15292440
NOTCH3.GENEBODY
SCLC-A
R
chr19: 15292399-
Island







15292632


cg18099070
chr7: 157845265
PTPRN2.GENEBODY
SCLC-A
R


cg18777231
chr20: 62669807
NCRNA00176.GENEBODY
SCLC-A
F
chr20: 62669304-
Island







62670730


cg26425555
chr5: 16616459
FAM134B.GENEBODY
SCLC-A
F
chr5: 16616509-
N_Shore







16617428


cg26532826
chr22: 31003127
TCN2.TSS200
SCLC-A
R


cg27269561
chr16: 3072713
HCFC1R1.UTR3
SCLC-A
F
chr16: 3073686-3074443
N_Shore


cg26147269
chr3: 13520256
HDAC11.TSS1500
SCLC-A
F
chr3: 13520912-
N_Shore







13521319


cg14632140
chr12: 16758112
LMO3.UTR5
SCLC-A
R


cg17107112
chr6: 34021546
GRM4.GENEBODY
SCLC-A
R
chr6: 34024201-
N_Shelf







34024457


cg19091386
chr7: 157435297
PTPRN2.GENEBODY
SCLC-A
F


cg04657700
chr2: 223535084
MOGAT1.TSS1500
SCLC-A
F
chr2: 223536122-
N_Shore







223536565


cg09890699
chr1: 54821853
SSBP3.GENEBODY
SCLC-A
R
chr1: 54821990-
N_Shore







54822333


cg12132731
chr1: 205313575
KLHDC8A.UTR5
SCLC-A
F
chr1: 205312493-
Island







205313576


cg14882082
chr14: 100845427
WDR25.UTR5
SCLC-A
F
chr14: 100842339-
S_Shelf







100842931


cg16071713
chr21: 36412456
C21orf96.TSS1500
SCLC-A
F


cg17956079
chr11: 73358572
PLEKHB1.TSS200
SCLC-A
R


cg18831409
chr6: 10585851
GCNT2.GENEBODY
SCLC-A
F


cg23674344
chr17: 48503163
ACSF2.TSS1500
SCLC-A
F
chr17: 48503056-
Island







48503887


cg00489219
chr3: 40566141
ZNF621.TSS1500
SCLC-A
F
chr3: 40566129-
Island







40566689


cg01731355
chr7: 158103582
PTPRN2.GENEBODY
SCLC-A
F
chr7: 158103336-
Island







158103601


cg05116002
chr3: 58151255
FLNB.GENEBODY
SCLC-A
R


cg05264223
chr15: 70126776
C15orf50.TSS1500
SCLC-A
F


cg05518803
chr10: 124739553
PSTK.TSS200
SCLC-A
R
chr10: 124739792-
N_Shore







124740292


cg08230118
chr6: 30181847
TRIM26.TSS1500
SCLC-A
R
chr6: 30180933-
Island







30182187


cg10451262
chr8: 124284176
ZHX1.UTR5
SCLC-A
R
chr8: 124286209-
N_Shelf







124287666


cg12233379
chr1: 151812524
LOC100132111.GENEBODY
SCLC-A
F
chr1: 151812253-
Island







151812525


cg13275679
chr17: 73151149
HN1.TSS1500
SCLC-A
R
chr17: 73149830-
S_Shore







73150885


cg16522557
chr13: 111159111
COL4A2.GENEBODY
SCLC-A
F


cg20427144
chr7: 5518918
FBXL18.UTR3
SCLC-A
F
chr7: 5521368-5521615
N_Shelf


cg20806345
chr2: 182543706
NEUROD1.UTR5
SCLC-A
F


cg09565319
chr6: 168963731
SMOC2.GENEBODY
SCLC-A
R


cg02185402
chr20: 400361
RBCK1.GENEBODY
SCLC-A
F
chr20: 400244-400469
Island


cg03721064
chr7: 50535834
DDC.GENEBODY
SCLC-A
R
chr7: 50535740-
Island







50535953


cg07908874
chr10: 135123006
ZNF511.GENEBODY
SCLC-A
R
chr10: 135122851-
Island







135123109


cg11785537
chr12: 6484729
SCNN1A.GENEBODY
SCLC-A
F


cg18011899
chr7: 158124253
PTPRN2.GENEBODY
SCLC-A
F


cg21913981
chr12: 120151706
MIR1178.TSS200
SCLC-A
R


cg23967873
chr10: 72977537
UNC5B.GENEBODY
SCLC-A
R
chr10: 72977123-
Island







72977774


cg26363039
chr12: 1609549
LOC100292680.TSS200
SCLC-A
R


cg27430662
chr1: 109656708
KIAA1324.UTR5
SCLC-A
R
chr1: 109656095-
S_Shore







109656611


cg00870849
chr10: 94003008
CPEB3.UTR5
SCLC-A
F
chr10: 93999131-
S_Shelf







94000015


cg05765011
chr16: 4103225
ADCY9.GENEBODY
SCLC-A
F


cg08521073
chr12: 117314052
HRK.UTR3
SCLC-A
R
chr12: 117316389-
N_Shelf







117317611


cg12218991
chr4: 152042934
SH3D19.UTR3
SCLC-A
F


cg14014950
chr3: 64125334
PRICKLE2.GENEBODY
SCLC-A
R


cg14220262
chr1: 1114963
TTLL10.GENEBODY
SCLC-A
F
chr1: 1115574-1116006
N_Shore


cg18104606
chr6: 70990361
COL9A1.GENEBODY
SCLC-A
R
chr6: 70992040-
N_Shore







70992912


cg20417351
chr17: 424358
VPS53.GENEBODY
SCLC-A
R


cg01154445
chr2: 206548171
NRP2.GENEBODY
SCLC-A
F
chr2: 206549599-
N_Shore







206551316


cg01804664
chr5: 149669414
CAMK2A.TSS200
SCLC-A
F


cg04569165
chrX: 153688677
PLXNA3.GENEBODY
SCLC-A
F
chrX: 153688592-
Island







153688860


cg04957757
chr16: 70463218
ST3GAL2.UTR5
SCLC-A
R


cg07660671
chr8: 10586967
SOX7.GENEBODY
SCLC-A
F
chr8: 10587304-
N_Shore







10591109


cg09354317
chr3: 52869307
MUSTN1.TSS200
SCLC-A
F


cg10724947
chr15: 62359485
C2CD4A.UTR5
SCLC-A
F
chr15: 62359827-
N_Shore







62360995


cg11484283
chr4: 159816181
FNIP2.GENEBODY
SCLC-A
F


cg12271047
chr7: 157387106
PTPRN2.GENEBODY
SCLC-A
R
chr7: 157387053-
Island







157387322


cg17833037
chr12: 123259751
CCDC62.GENEBODY
SCLC-A
R


cg19563107
chr14: 53418879
FERMT2.TSS1500
SCLC-A
R
chr14: 53417108-
S_Shore







53418339


cg20354580
chr3: 128713146
KIAA1257.TSS200
SCLC-A
R
chr3: 128712404-
S_Shore







128713058


cg22110158
chr11: 130036542
ST14.GENEBODY
SCLC-A
F


cg22369288
chr6: 138538817
PBOV1.EXON1
SCLC-A
R


cg22514229
chr1: 94118054
BCAR3.GENEBODY
SCLC-A
R


cg02954284
chr22: 21367447
MGC16703.GENEBODY
SCLC-A
R
chr22: 21368197-
N_Shore







21368771


cg04765195
chr6: 36209753
PNPLA1.TSS1500
SCLC-A
F


cg08059112
chr19: 2294887
LINGO3.UTR5
SCLC-A
R
chr19: 2294886-2295101
Island


cg09508022
chr6: 168971135
SMOC2.GENEBODY
SCLC-A
F
chr6: 168972516-
N_Shore







168974109


cg09915444
chr15: 62359275
C2CD4A.EXON1
SCLC-A
F
chr15: 62359827-
N_Shore







62360995


cg13859860
chr10: 51569878
NCOA4.UTR5
SCLC-A
F
chr10: 51572198-
N_Shelf







51572620


cg14666908
chr6: 31937758
STK19.TSS1500
SCLC-A
R
chr6: 31939730-
N_Shore







31940559


cg15744134
chr15: 32933835
SCG5.TSS200
SCLC-A
R


cg16404364
chr7: 1006746
COX19.UTR3
SCLC-A
F
chr7: 1007159-1007558
N_Shore


cg19711579
chr2: 182545562
NEUROD1.TSS200
SCLC-A
F
chr2: 182547873-
N_Shelf







182549177


cg20587332
chr8: 40736768
ZMAT4.UTR5
SCLC-A
R


cg21276549
chr13: 102568345
FGF14.GENEBODY
SCLC-A
F
chr13: 102568425-
N_Shore







102569495


cg21390575
chr4: 185747721
ACSL1.TSS1500
SCLC-A
R
chr4: 185746557-
Island







185747827


cg22976218
chr2: 182544321
NEUROD1.UTR5
SCLC-A
R
chr2: 182547873-
N_Shelf







182549177


cg03569876
chr5: 148908014
CSNK1A1.GENEBODY
SCLC-A
R


cg03674563
chr11: 422260
ANO9.GENEBODY
SCLC-A
R
chr11: 420265-420975
S_Shore


cg03905369
chr2: 120824615
EPB41L5.GENEBODY
SCLC-A
F


cg06374811
chr6: 22099667
FLJ22536.GENEBODY
SCLC-A
R


cg14795528
chr7: 157451260
PTPRN2.GENEBODY
SCLC-A
F
chr7: 157453774-
N_Shelf







157454208


cg19359218
chr6: 30181936
TRIM26.TSS1500
SCLC-A
R
chr6: 30180933-
Island







30182187


cg20143111
chr4: 10673188
CLNK.UTR5
SCLC-A
R


cg21163701
chr8: 85165845
RALYL.UTR5
SCLC-A
F


cg26743132
chr13: 111107905
COL4A2.GENEBODY
SCLC-A
F
chr13: 111109139-
N_Shore







111109652


cg09918657
chr16: 14397207
MIR193B.TSS1500
SCLC-A
R
chr16: 14395604-
S_Shore







14397075


cg19754622
chr10: 134045578
STK32C.GENEBODY
SCLC-A
F
chr10: 134041499-
S_Shelf







134041784


cg03769629
chr6: 30181591
TRIM26.TSS1500
SCLC-A
R
chr6: 30180933-
Island







30182187


cg05640721
chr15: 90437833
AP3S2.TSS1500
SCLC-A
F
chr15: 90437025-
S_Shore







90437602


cg06059849
chr1: 109656930
KIAA1324.EXON1
SCLC-A
F
chr1: 109656095-
S_Shore







109656611


cg12609243
chr3: 54155240
CACNA2D3.TSS1500
SCLC-A
R
chr3: 54155239-
Island







54157025


cg19744528
chr7: 157553346
PTPRN2.GENEBODY
SCLC-A
F
chr7: 157550547-
S_Shelf







157551025


cg22222281
chr12: 6308758
CD9.TSS1500
SCLC-A
R
chr12: 6309152-6310392
N_Shore


cg22740141
chr12: 129454194
GLT1D1.GENEBODY
SCLC-A
F


cg25191573
chr3: 49037070
P4HTM.GENEBODY
SCLC-A
R


cg25903363
chr8: 21972479
HR.UTR3
SCLC-A
R


cg00321901
chr8: 10512459
RP1L1.EXON1
SCLC-A
R


cg03695433
chr17: 71332907
SDK2.UTR3
SCLC-A
F


cg04628438
chr6: 10585889
GCNT2.GENEBODY
SCLC-A
F


cg14981313
chr1: 42847055
RIMKLA.GENEBODY
SCLC-A
R
chr1: 42845978-
S_Shore







42846988


cg24408763
chr6: 43446221
TJAP1.UTR5
SCLC-A
R


cg24603926
chr12: 120151679
MIR1178.TSS200
SCLC-A
R


cg27098470
chr22: 42828411
NFAM1.TSS200
SCLC-A
R


cg02102889
chr4: 139164723
SLC7A11.TSS1500
SCLC-A
R


cg02910913
chr17: 72968277
C17orf28.GENEBODY
SCLC-A
R
chr17: 72968167-
Island







72969164


cg04176122
chr11: 118779835
BCL9L.GENEBODY
SCLC-A
F
chr11: 118781060-
N_Shore







118781732


cg06023257
chr11: 78129396
GAB2.TSS1500
SCLC-A
F
chr11: 78127965-
Island







78129400


cg06233018
chr21: 41552656
DSCAM.GENEBODY
SCLC-A
F
chr21: 41554618-
N_Shore







41554959


cg15409237
chr19: 51524249
KLK10.TSS1500
SCLC-A
F
chr19: 51522004-
S_Shore







51522803


cg17401435
chr11: 63887426
MACROD1.GENEBODY
SCLC-A
F
chr11: 63887355-
Island







63887600


cg19008877
chr10: 78157854
C10orf11.GENEBODY
SCLC-A
R


cg21275690
chr16: 3072970
HCFC1R1.GENEBODY
SCLC-A
F
chr16: 3073686-3074443
N_Shore


cg26216243
chr6: 49495283
GLYATL3.UTR3
SCLC-A
F


cg11286977
chr6: 30181713
TRIM26.TSS1500
SCLC-A
R
chr6: 30180933-
Island







30182187


cg01027553
chr7: 4037843
SDK1.GENEBODY
SCLC-A
F


cg01155325
chr15: 42719757
ZFP106.GENEBODY
SCLC-A
R


cg06714480
chr2: 182544307
NEUROD1.UTR5
SCLC-A
R
chr2: 182547873-
N_Shelf







182549177


cg07181952
chr1: 1239999
ACAP3.GENEBODY
SCLC-A
F
chr1: 1242400-1245185
N_Shelf


cg09306186
chr16: 73081722
ZFHX3.EXON1
SCLC-A
F
chr16: 73081590-
Island







73082565


cg10545682
chr1: 151512625
TUFT1.TSS200
SCLC-A
F
chr1: 151512661-
N_Shore







151513199


cg10769178
chr7: 157876300
PTPRN2.GENEBODY
SCLC-A
R


cg20709008
chr2: 182545934
NEUROD1.TSS1500
SCLC-A
F
chr2: 182547873-
N_Shore







182549177


cg24440468
chr7: 73184642
CLDN3.TSS200
SCLC-A
R
chr7: 73183379-
Island







73185115


cg25356639
chr3: 71349304
FOXP1.UTR5
SCLC-A
F


cg26824709
chr5: 159740383
CCNJL.TSS1500
SCLC-A
R
chr5: 159738781-
S_Shore







159739913


cg01461199
chr8: 121822473
SNTB1.GENEBODY
SCLC-A
F
chr8: 121823534-
N_Shore







121824720


cg01788682
chr3: 15382723
SH3BP5.UTR5
SCLC-A
F


cg03721293
chr16: 90014378
DEF8.TSS1500
SCLC-A
F
chr16: 90014250-
Island







90014613


cg03893692
chr5: 149669484
CAMK2A.TSS200
SCLC-A
F


cg07109923
chr20: 35091317
DLGAP4.GENEBODY
SCLC-A
R
chr20: 35089448-
S_Shore







35089998


cg11964773
chr1: 14924077
KIAA1026.TSS1500
SCLC-A
F
chr1: 14924610-
N_Shore







14925993


cg13538006
chr9: 95897313
NINJ1.TSS1500
SCLC-A
R
chr9: 95896007-
S_Shore







95897016


cg13818276
chr22: 32437865
SLC5A1.TSS1500
SCLC-A
R
chr22: 32439046-
N_Shore







32439442


cg08530036
chr1: 19496406
UBR4.GENEBODY
SCLC-A
R


cg09388414
chr7: 129414651
MIR96.TSS200
SCLC-A
R
chr7: 129418286-
N_Shelf







129422509


cg18124764
chr7: 101558698
CUX1.GENEBODY
SCLC-A
F
chr7: 101559402-
N_Shore







101559625


cg23406864
chr22: 21053952
TMEM191A.TSS1500
SCLC-A
R
chr22: 21056258-
N_Shelf







21058793


cg23731742
chr1: 879958
NOC2L.UTR3
SCLC-A
R
chr1: 875730-878363
S_Shore


cg00336946
chr13: 101186274
A2LD1.TSS1500
SCLC-A
F
chr13: 101184396-
S_Shore







101184848


cg00735329
chr18: 74732603
MBP.GENEBODY
SCLC-A
R


cg02375832
chr11: 62437615
C11orf48.UTR5
SCLC-A
R
chr11: 62439047-
N_Shore







62439803


cg04757345
chr4: 128918835
C4orf29.GENEBODY
SCLC-A
F


cg11744304
chr7: 100875822
CLDN15.GENEBODY
SCLC-A
R
chr7: 100875555-
Island







100876212


cg16027376
chr8: 144653975
C8orf73.GENEBODY
SCLC-A
F
chr8: 144653774-
Island







144653976


cg19681793
chr6: 169651645
THBS2.UTR5
SCLC-A
R
chr6: 169648546-
S_Shelf







169649047


cg21486510
chr2: 7171998
RNF144A.GENEBODY
SCLC-A
F
chr2: 7172296-7172512
N_Shore


cg21761356
chr12: 97892013
RMST.GENEBODY
SCLC-A
F


cg22332321
chr20: 62510260
TPD52L2.GENEBODY
SCLC-A
R
chr20: 62509163-
S_Shore







62509369


cg22817352
chr1: 204653629
LRRN2.UTR5
SCLC-A
F
chr1: 204654132-
N_Shore







204654885


cg17553353
chr3: 111718565
TAGLN3.GENEBODY
SCLC-A
R


cg02703870
chr16: 82045140
SDR42E1.TSS200
SCLC-A
R
chr16: 82044886-
Island







82045306


cg03723730
chr6: 34031694
GRM4.GENEBODY
SCLC-A
F


cg13314260
chr5: 141349631
RNF14.UTR5
SCLC-A
R
chr5: 141348531-
S_Shore







141349104


cg20660385
chr19: 51526587
KLK11.GENEBODY
SCLC-A
R
chr19: 51522004-
S_Shelf







51522803


cg20708173
chr4: 7940426
AFAP1.UTR5
SCLC-A
R
chr4: 7940563-7941853
N_Shore


cg23218957
chr14: 59109856
DACT1.GENEBODY
SCLC-A
R
chr14: 59113071-
N_Shelf







59113640


cg02641676
chr8: 42397764
C8orf40.UTR5
SCLC-A
R
chr8: 42396235-
S_Shore







42397195


cg06829681
chr11: 12867453
TEAD1.GENEBODY
SCLC-A
F


cg09565670
chr19: 39368408
RINL.UTR5
SCLC-A
R


cg14660446
chr19: 48015621
NAPA.GENEBODY
SCLC-A
F
chr19: 48017717-
N_Shelf







48018782


cg19296671
chr11: 128562297
FLI1.TSS200
SCLC-A
R
chr11: 128562671-
N_Shore







128565011


cg02921634
chr21: 43109546
NCRNA00111.GENEBODY
SCLC-A
F
chr21: 43109349-
Island







43109687


cg03365751
chr22: 42828386
NFAM1.EXON1
SCLC-A
F


cg06136185
chr17: 79139087
LOC388428.TSS1500
SCLC-A
R
chr17: 79139501-
N_Shore







79140028


cg06963053
chr2: 182545533
NEUROD1.TSS200
SCLC-A
F
chr2: 182547873-
N_Shelf







182549177


cg07915206
chr15: 34260555
AVEN.GENEBODY
SCLC-A
R


cg10806639
chr13: 33780078
STARD13.EXON1
SCLC-A
R


cg18314778
chr7: 157468321
PTPRN2.GENEBODY
SCLC-A
F


cg18798446
chr12: 103862780
C12orf42.GENEBODY
SCLC-A
F


cg20970369
chr1: 111744108
DENND2D.TSS1500
SCLC-A
F
chr1: 111746337-
N_Shelf







111747303


cg21244086
chr15: 45479462
SHF.GENEBODY
SCLC-A
F
chr15: 45479509-
N_Shore







45480498


cg10159951
chr11: 35441881
SLC1A2.TSS1500
SCLC-A
F
chr11: 35440375-
Island







35441882


cg10614445
chr2: 25526696
DNMT3A.GENEBODY
SCLC-A
F


cg15873327
chr19: 8398677
KANK3.GENEBODY
SCLC-A
F
chr19: 8397958-8400461
Island


cg22486214
chr17: 78930466
RPTOR.GENEBODY
SCLC-A
F


cg25043538
chr11: 63887437
MACROD1.GENEBODY
SCLC-A
R
chr11: 63887355-
Island







63887600


cg25960403
chr4: 11370015
MIR572.TSS1500
SCLC-A
F
chr4: 11370229-
N_Shore







11370886


cg01670896
chr8: 1933522
KBTBD11.UTR5
SCLC-A
F


cg01643250
chr19: 15292485
NOTCH3.GENEBODY
SCLC-A
R
chr19: 15292399-
Island







15292632


cg02959939
chr21: 47813025
PCNT.GENEBODY
SCLC-A
F
chr21: 47813251-
N_Shore







47813462


cg07533617
chr11: 117624926
DSCAML1.GENEBODY
SCLC-A
R


cg09824889
chr3: 121311075
FBXO40.TSS1500
SCLC-A
R


cg10143807
chr1: 155050924
EFNA3.TSS1500
SCLC-A
F
chr1: 155051155-
N_Shore







155055291


cg11445764
chr5: 147773164
FBXO38.UTR5
SCLC-A
R


cg14765206
chr10: 101744219
DNMBP.UTR5
SCLC-A
R


cg19239304
chr2: 238621429
LRRFIP1.GENEBODY
SCLC-A
R


cg20147326
chr11: 33913538
LMO2.EXON1
SCLC-A
R


cg21798544
chr11: 924646
AP2A2.TSS1500
SCLC-A
R
chr11: 925183-926083
N_Shore


cg24918790
chr22: 20785148
SCARF2.GENEBODY
SCLC-A
F
chr22: 20783466-
Island







20786201


cg26142132
chr17: 74463585
AANAT.TSS200
SCLC-A
R


cg03368643
chr6: 30181600
TRIM26.TSS1500
SCLC-A
R
chr6: 30180933-
Island







30182187


cg07827420
chr17: 75371764
SEPT9.UTR5
SCLC-A
F
chr17: 75368688-
S_Shore







75370506


cg15935860
chr1: 201282499
PKP1.GENEBODY
SCLC-A
F


cg26813796
chr1: 225806065
ENAH.GENEBODY
SCLC-A
R


cg19778462
chr1: 41976072
HIVEP3.UTR3
SCLC-A
F


cg22149419
chr17: 27253138
PHF12.GENEBODY
SCLC-A
R


cg24994355
chr10: 99445520
AVPI1.UTR5
SCLC-A
F
chr10: 99446696-
N_Shore







99447400


cg10965131
chr7: 151078995
WDR86.GENEBODY
SCLC-A
R
chr7: 151078462-
Island







151079536


cg12710538
chr17: 27490340
MYO18A.GENEBODY
SCLC-A
F
chr17: 27493203-
N_Shelf







27493880


cg13250203
chr11: 1565798
HCCA2.GENEBODY
SCLC-A
R
chr11: 1567940-1568907
N_Shelf


cg13302670
chr7: 44261293
CAMK2B.GENEBODY
SCLC-A
F
chr7: 44259669-
S_Shore







44259923


cg17522866
chr5: 147052374
JAKMIP2.UTR5
SCLC-A
F


cg25147139
chr12: 49740718
DNAJC22.TSS1500
SCLC-A
R
chr12: 49738680-
Island







49740841


cg26245202
chr1: 205602864
ELK4.TSS1500
SCLC-A
F
chr1: 205600493-
S_Shore







205601432


cg26317549
chr15: 48497296
SLC12A1.TSS1500
SCLC-A
R


cg01474011
chr2: 225435131
CUL3.GENEBODY
SCLC-A
F


cg02737268
chr20: 3780182
CDC25B.GENEBODY
SCLC-A
F
chr20: 3776198-3776419
S_Shelf


cg08549332
chr7: 101558461
CUX1.GENEBODY
SCLC-A
F
chr7: 101559402-
N_Shore







101559625


cg12108651
chr7: 158193742
PTPRN2.GENEBODY
SCLC-A
F


cg16935790
chr17: 77043246
C1QTNF1.GENEBODY
SCLC-A
R
chr17: 77043741-
N_Shore







77044489


cg21285555
chr8: 52771466
PCMTD1.GENEBODY
SCLC-A
R


cg26808293
chr16: 3072207
TNFRSF12A.UTR3
SCLC-A
R
chr16: 3073686-3074443
N_Shore


cg04956949
chr7: 73119262
STX1A.GENEBODY
SCLC-A
F
chr7: 73118500-
S_Shore







73118749


cg08519905
chr12: 6308774
CD9.TSS1500
SCLC-A
R
chr12: 6309152-6310392
N_Shore


cg09560636
chr5: 43631579
NNT.GENEBODY
SCLC-A
R


cg12400725
chr1: 29240533
EPB41.UTR5
SCLC-A
R
chr1: 29240768-
N_Shore







29241969


cg15298719
chr17: 7165255
CLDN7.EXON1
SCLC-A
R
chr17: 7164285-7166245
Island


cg19397765
chr6: 30181764
TRIM26.TSS1500
SCLC-A
R
chr6: 30180933-
Island







30182187


cg21585162
chr11: 128566387
FLI1.GENEBODY
SCLC-A
F
chr11: 128562671-
S_Shore







128565011


cg25004427
chr5: 326523
AHRR.GENEBODY
SCLC-A
R
chr5: 320788-323010
S_Shelf


cg01609559
chr6: 46138957
ENPP5.TSS1500
SCLC-A
R


cg08821738
chr17: 77043179
C1QTNF1.GENEBODY
SCLC-A
F
chr17: 77043741-
N_Shore







77044489


cg10690467
chr12: 70047752
BEST3.UTR3
SCLC-A
R


cg14570838
chr11: 128562353
FLI1.TSS1500
SCLC-A
F
chr11: 128562671-
N_Shore







128565011


cg17397159
chr4: 720144
PCGF3.UTR5
SCLC-A
F
chr4: 716281-716977
S_Shelf


cg18601229
chr15: 42192297
EHD4.UTR3
SCLC-A
R
chr15: 42192913-
N_Shore







42193255


cg21445398
chr2: 125425654
CNTNAP5.GENEBODY
SCLC-A
F


cg00162859
chr8: 131268256
ASAP1.GENEBODY
SCLC-A
F


cg02659920
chr11: 726335
EPS8L2.GENEBODY
SCLC-A
F
chr11: 725596-726870
Island


cg03852018
chr2: 149634410
KIF5C.GENEBODY
SCLC-A
F
chr2: 149632682-
S_Shore







149633882


cg04801402
chr6: 46138912
ENPP5.TSS200
SCLC-A
F


cg08162476
chr3: 13064001
IQSEC1.GENEBODY
SCLC-A
R


cg08472795
chr2: 129067253
HS6ST1.GENEBODY
SCLC-A
F


cg02893260
chr13: 30071603
MTUS2.GENEBODY
SCLC-A
R


cg03508204
chr2: 129057540
HS6ST1.GENEBODY
SCLC-A
F


cg04176557
chr11: 75902270
WNT11.GENEBODY
SCLC-A
R
chr11: 75905717-
N_Shelf







75905918


cg05230392
chr17: 55976522
CUEDC1.UTR5
SCLC-A
F


cg05912053
chr15: 60919520
RORA.GENEBODY
SCLC-A
R


cg08918013
chr19: 55953951
SHISA7.EXON1
SCLC-A
R
chr19: 55953371-
Island







55954641


cg12758867
chr11: 65354231
EHBP1L1.GENEBODY
SCLC-A
F
chr11: 65352231-
S_Shore







65353134


cg13889934
chr4: 86851399
ARHGAP24.GENEBODY
SCLC-A
F


cg14454073
chr14: 50159754
KLHDC1.TSS200
SCLC-A
F
chr14: 50159667-
Island







50160424


cg14475480
chr17: 79655469
HGS.GENEBODY
SCLC-A
R
chr17: 79655162-
Island







79655515


cg18041814
chr6: 36802896
CPNE5.GENEBODY
SCLC-A
F
chr6: 36806881-
N_Shelf







36807217


cg20735041
chr3: 52869266
MUSTN1.TSS200
SCLC-A
R


cg25693302
chr18: 55862678
NEDD4L.UTR5
SCLC-A
R
chr18: 55862653-
Island







55862873


cg04658856
chr6: 16242468
GMPR.GENEBODY
SCLC-A
R
chr6: 16238589-
S_Shelf







16239231


cg05004108
chr1: 85931167
DDAH1.TSS1500
SCLC-A
F
chr1: 85929940-
Island







85931168


cg14986845
chr6: 30182240
TRIM26.TSS1500
SCLC-A
R
chr6: 30180933-
S_Shore







30182187


cg15742605
chr1: 879383
SAMD11.GENEBODY
SCLC-A
F
chr1: 875730-878363
S_Shore


cg19713140
chr7: 157584994
PTPRN2.GENEBODY
SCLC-A
F
chr7: 157586711-
N_Shore







157587112


cg20894936
chr11: 1630266
HCCA2.GENEBODY
SCLC-A
F


cg21060736
chr15: 73618666
HCN4.GENEBODY
SCLC-A
F


cg23417096
chr8: 134250016
NDRG1.UTR3
SCLC-A
R


cg27104413
chr3: 101044447
SENP7.UTR3
SCLC-A
R


cg21648069
chr12: 1157718
ERC1.GENEBODY
SCLC-A
F


cg00192882
chr17: 19291120
MFAP4.TSS1500
SCLC-A
R


cg02838877
chr13: 97873877
MBNL2.TSS1500
SCLC-A
R


cg03841136
chr21: 43136835
NCRNA00112.GENEBODY
SCLC-A
R


cg07701837
chr2: 210516795
MAP2.UTR5
SCLC-A
F


cg09591406
chr17: 3833873
ATP2A3.GENEBODY
SCLC-A
R


cg09901529
chr10: 75437967
AGAP5.GENEBODY
SCLC-A
F
chr10: 75434361-
S_Shelf







75434584


cg25595636
chr11: 61278148
LRRC10B.EXON1
SCLC-A
F
chr11: 61275825-
S_Shore







61277329


cg02716826
chr9: 33447032
SUGT1P1.GENEBODY
SCLC-A
R
chr9: 33447446-
N_Shore







33447824


cg07017242
chr7: 128047441
IMPDH1.GENEBODY
SCLC-A
F
chr7: 128045542-
S_Shore







128046298


cg13356427
chr1: 6520354
ESPN.UTR3
SCLC-A
F
chr1: 6520584-6521955
N_Shore


cg16944941
chr11: 70391346
SHANK2.GENEBODY
SCLC-A
F


cg18264519
chr2: 97214296
ARID5A.GENEBODY
SCLC-A
F
chr2: 97215788-
N_Shore







97216225


cg19626737
chr15: 68633792
ITGA11.GENEBODY
SCLC-A
F


cg21745110
chr11: 19798742
NAV2.GENEBODY
SCLC-A
R
chr11: 19798537-
Island







19798949


cg04098194
chr1: 1241087
ACAP3.GENEBODY
SCLC-A
R
chr1: 1242400-1245185
N_Shore


cg07524505
chr11: 44785843
TSPAN18.TSS200
SCLC-A
R


cg11808936
chr4: 7894203
AFAP1.UTR5
SCLC-A
F


cg14157527
chr9: 132937709
FREQ.GENEBODY
SCLC-A
R
chr9: 132934213-
S_Shelf







132934483


cg16371032
chr8: 95654541
ESRP1.GENEBODY
SCLC-A
F
chr8: 95653898-
Island







95654733


cg11503687
chr5: 138205434
CTNNA1.GENEBODY
SCLC-A
F


cg12116749
chr10: 21245178
NEBL.GENEBODY
SCLC-A
R


cg02047211
chr17: 78932697
RPTOR.GENEBODY
SCLC-A
R
chr17: 78935043-
N_Shelf







78935307


cg02839802
chr22: 38963969
DMC1.GENEBODY
SCLC-A
F
chr22: 38965733-
N_Shore







38966196


cg04278162
chr6: 30182172
TRIM26.TSS1500
SCLC-A
F
chr6: 30180933-
Island







30182187


cg19918429
chr3: 122399781
PARP14.EXON1
SCLC-A
F
chr3: 122399655-
Island







122400190


cg00156118
chr2: 85473750
TCF7L1.GENEBODY
SCLC-A
R


cg04545079
chr16: 67599924
CTCF.UTR5
SCLC-A
R
chr16: 67595868-
S_Shelf







67597554


cg07633435
chr5: 152869009
GRIA1.TSS1500
SCLC-A
F


cg20129210
chr13: 100547192
CLYBL.UTR3
SCLC-A
R
chr13: 100547172-
Island







100547431


cg08692676
chr6: 134299594
TBPL1.UTR5
SCLC-A
R


cg09342325
chr2: 220371699
GMPPA.UTR3
SCLC-A
F


cg10207240
chr12: 122356781
WDR66.UTR5
SCLC-A
R
chr12: 122356315-
Island







122356853


cg11314042
chr6: 143380966
AIG1.TSS1500
SCLC-A
F
chr6: 143381444-
N_Shore







143381918


cg14326805
chr9: 71737756
TJP2.UTR5
SCLC-A
F
chr9: 71736074-
S_Shore







71737367


cg15018282
chr6: 30181877
TRIM26.TSS1500
SCLC-A
R
chr6: 30180933-
Island







30182187


cg25887619
chr7: 101558435
CUX1.GENEBODY
SCLC-A
R
chr7: 101559402-
N_Shore







101559625


cg00970752
chr1: 15711443
FHAD1.GENEBODY
SCLC-A
R


cg02017200
chr19: 49256361
FUT1.UTR5
SCLC-A
F
chr19: 49255778-
Island







49256495


cg03477240
chr6: 20583779
CDKAL1.GENEBODY
SCLC-A
F


cg03850117
chr16: 87894334
SLC7A5.GENEBODY
SCLC-A
R
chr16: 87894359-
N_Shore







87894566


cg15509065
chr19: 36346314
KIRREL2.TSS1500
SCLC-A
F
chr19: 36347044-
N_Shore







36348101


cg16105461
chr11: 61485853
DAGLA.UTR5
SCLC-A
F
chr11: 61488132-
N_Shelf







61488357


cg16933706
chr6: 30181934
TRIM26.TSS1500
SCLC-A
R
chr6: 30180933-
Island







30182187


cg19139618
chr17: 46504791
SKAP1.GENEBODY
SCLC-A
R
chr17: 46507344-
N_Shelf







46507778


cg21804531
chr14: 90419290
C14orf143.GENEBODY
SCLC-A
F
chr14: 90420900-
N_Shore







90421175


cg23735214
chr11: 77595033
INTS4.GENEBODY
SCLC-A
F


cg26329692
chr17: 73126757
NT5C.GENEBODY
SCLC-A
R
chr17: 73127196-
N_Shore







73127995


cg03478739
chr2: 175712381
CHN1.GENEBODY
SCLC-A
F


cg04687437
chr19: 511113
C19orf20.GENEBODY
SCLC-A
F
chr19: 506526-507133
S_Shelf


cg04828792
chr21: 42733433
MX2.TSS1500
SCLC-A
F


cg08258650
chr11: 35441900
SLC1A2.TSS1500
SCLC-A
F
chr11: 35440375-
S_Shore







35441882


cg08348709
chr17: 37764802
NEUROD2.TSS1500
SCLC-A
F
chr17: 37761691-
S_Shore







37763551


cg09195271
chr1: 20142497
RNF186.TSS1500
SCLC-A
R


cg10515731
chr2: 220378996
ACCN4.UTR5
SCLC-A
F
chr2: 220377743-
S_Shore







220377946


cg18085176
chr4: 7939940
AFAP1.UTR5
SCLC-A
F
chr4: 7940563-7941853
N_Shore


cg22776856
chr16: 3072572
THOC6.TSS1500
SCLC-A
R
chr16: 3073686-3074443
N_Shore


cg25846061
chr2: 236415673
AGAP1.GENEBODY
SCLC-A
R


cg00785029
chr21: 43491755
UMODL1.GENEBODY
SCLC-A
R


cg01226742
chr8: 37699923
GPR124.UTR3
SCLC-A
F
chr8: 37698846-
Island







37699931


cg04304450
chr22: 43525431
BIK.UTR3
SCLC-A
F


cg04355435
chr1: 43736290
TMEM125.UTR5
SCLC-A
F
chr1: 43738484-
N_Shelf







43738829


cg06804344
chr3: 128778699
GP9.TSS1500
SCLC-A
F


cg06865992
chr17: 37764503
NEUROD2.TSS1500
SCLC-A
R
chr17: 37761691-
S_Shore







37763551


cg08374799
chr12: 53601050
ITGB7.TSS200
SCLC-A
R


cg08427782
chr6: 166880989
RPS6KA2.GENEBODY
SCLC-A
F


cg10483275
chr5: 149669368
CAMK2A.UTR5
SCLC-A
F


cg14059959
chr13: 111144447
COL4A2.GENEBODY
SCLC-A
R


cg18498622
chrX: 151810246
GABRQ.GENEBODY
SCLC-A
F
chrX: 151806233-
S_Shelf







151806947


cg20192387
chr6: 166856056
RPS6KA2.GENEBODY
SCLC-A
R


cg21917090
chr4: 77816250
ANKRD56.UTR3
SCLC-A
R
chr4: 77818015-
N_Shore







77819600


cg22359606
chr2: 182545492
NEUROD1.TSS200
SCLC-A
F
chr2: 182547873-
N_Shelf







182549177


cg24554839
chr1: 166124903
MIR921.TSS1500
SCLC-A
F


cg25788549
chr7: 150786044
AGAP3.GENEBODY
SCLC-A
F
chr7: 150783480-
S_Shore







150785040


cg06961289
chr1: 156722410
HDGF.TSS200
SCLC-A
F
chr1: 156720747-
S_Shore







156722069


cg08671326
chr3: 194967958
C3orf21.GENEBODY
SCLC-A
F


cg09726982
chr2: 220379016
ACCN4.UTR5
SCLC-A
F
chr2: 220377743-
S_Shore







220377946


cg13920460
chr9: 71735701
TJP2.TSS1500
SCLC-A
R
chr9: 71736074-
N_Shore







71737367


cg19482025
chr11: 128562245
FLI1.TSS200
SCLC-A
F
chr11: 128562671-
N_Shore







128565011


cg02746771
chr10: 527872
DIP2C.GENEBODY
SCLC-A
R
chr10: 525719-526041
S_Shore


cg04907173
chr11: 65060386
POLA2.GENEBODY
SCLC-A
F


cg05124770
chr22: 24578799
SUSD2.GENEBODY
SCLC-A
F
chr22: 24581632-
N_Shelf







24582127


cg17204557
chr2: 121223909
LOC84931.GENEBODY
SCLC-A
R


cg19778003
chr3: 111718062
TAGLN3.EXON1
SCLC-A
R


cg21177112
chr12: 63193647
PPM1H.GENEBODY
SCLC-A
F
chr12: 63195657-
N_Shelf







63195909


cg21781979
chr13: 100547292
CLYBL.UTR3
SCLC-A
F
chr13: 100547172-
Island







100547431


cg21963703
chr5: 140350766
PCDHA7.GENEBODY
SCLC-A
R
chr5: 140346105-
5.5







140346931
S_Shelf


cg22666115
chr6: 30182186
TRIM26.TSS1500
SCLC-A
F
chr6: 30180933-
Island







30182187


cg23641264
chr8: 143748641
JRK.UTR5
SCLC-A
F
chr8: 143750759-
N_Shelf







143751448


cg26064870
chr8: 102944342
NCALD.UTR5
SCLC-A
R


cg03979241
chr8: 21916824
EPB49.EXON1
SCLC-A
F
chr8: 21914275-
S_Shelf







21914525


cg07651914
chr7: 100881986
CLDN15.TSS1500
SCLC-A
F


cg13077545
chr17: 41832873
SOST.GENEBODY
SCLC-A
R
chr17: 41832717-
Island







41833195


cg13974838
chr9: 98221619
PTCH1.GENEBODY
SCLC-A
F


cg15612436
chr22: 43897902
MPPED1.GENEBODY
SCLC-A
R


cg16222790
chr8: 144521374
ZC3H3.GENEBODY
SCLC-A
R
chr8: 144521358-
Island







144521608


cg17066349
chr12: 120130646
CIT.GENEBODY
SCLC-A
F
chr12: 120127973-
S_Shelf







120128291


cg18127395
chr7: 95433546
DYNC111.UTR5
SCLC-A
F


cg25320780
chr1: 110933345
SLC16A4.UTR5
SCLC-A
F


cg26549084
chr3: 171759895
FNDC3B.UTR5
SCLC-A
F
chr3: 171757493-
S_Shore







171758724


cg27469783
chr19: 3801404
MATK.UTR5
SCLC-A
F
chr19: 3801392-3801819
Island


cg01877565
chr7: 129414746
MIR183.GENEBODY
SCLC-A
F
chr7: 129418286-
N_Shelf







129422509


cg03310469
chr2: 45236672
SIX2.TSS200
SCLC-A
F
chr2: 45235511-
Island







45237792


cg04305228
chr22: 18272333
MICAL3.UTR3
SCLC-A
R
chr22: 18275679-
N_Shelf







18275922


cg06433132
chr19: 39662346
PAK4.GENEBODY
SCLC-A
R
chr19: 39663600-
N_Shore







39663815


cg10832281
chr11: 35499741
PAMR1.GENEBODY
SCLC-A
F


cg14627862
chr6: 169641232
THBS2.GENEBODY
SCLC-A
F
chr6: 169641803-
N_Shore







169642020


cg19695266
chr1: 1241672
ACAP3.GENEBODY
SCLC-A
R
chr1: 1242400-1245185
N_Shore


cg21151061
chr12: 50498016
GPD1.GENEBODY
SCLC-A
R


cg22352709
chr3: 195446859
MUC20.TSS1500
SCLC-A
R


cg02619205
chr9: 117157157
AKNA.TSS1500
SCLC-A
F
chr9: 117160139-
N_Shelf







117161064


cg03539717
chr19: 13065086
GADD45GIP1.GENEBODY
SCLC-A
R
chr19: 13067585-
N_Shelf







13068152


cg04007028
chr17: 36735584
SRCIN1.GENEBODY
SCLC-A
R
chr17: 36734659-
S_Shore







36735246


cg05499054
chr8: 75148806
JPH1.UTR3
SCLC-A
R


cg07645286
chr2: 173604634
RAPGEF4.GENEBODY
SCLC-A
R
chr2: 173600281-
S_Shelf







173600970


cg11401784
chr1: 16092264
FBLIM1.GENEBODY
SCLC-A
R


cg14034852
chr17: 7165010
CLDN7.GENEBODY
SCLC-A
F
chr17: 7164285-7166245
Island


cg17111837
chr20: 62669757
NCRNA00176.GENEBODY
SCLC-A
R
chr20: 62669304-
Island







62670730


cg20126106
chr3: 111718135
TAGLN3.EXON1
SCLC-A
R


cg20491406
chr1: 201693818
NAV1.GENEBODY
SCLC-A
R


cg23377852
chr5: 1339812
CLPTM1L.GENEBODY
SCLC-A
F
chr5: 1339662-1340082
Island


cg00912746
chr1: 33350709
HPCA.TSS1500
SCLC-A
F
chr1: 33351686-
N_Shore







33352397


cg01557332
chr6: 169641045
THBS2.GENEBODY
SCLC-A
R
chr6: 169641803-
N_Shore







169642020


cg05304366
chr15: 40226905
EIF2AK4.GENEBODY
SCLC-A
F
chr15: 40226210-
S_Shore







40226631


cg08160706
chr16: 11876111
ZC3H7A.GENEBODY
SCLC-A
F


cg10716524
chr11: 474509
PTDSS2.GENEBODY
SCLC-A
R
chr11: 472781-473065
S_Shore


cg11410436
chr16: 52581609
TOX3.UTR5
SCLC-A
F
chr16: 52581293-
Island







52581610


cg19432362
chr13: 46426263
SIAH3.TSS1500
SCLC-A
F


cg21191365
chr14: 90529014
KCNK13.GENEBODY
SCLC-A
F
chr14: 90526696-
S_Shore







90528951


cg03107310
chr10: 86094757
FAM190B.UTR5
SCLC-A
F


cg06097994
chr17: 77043171
C1QTNF1.GENEBODY
SCLC-A
F
chr17: 77043741-
N_Shore







77044489


cg06923861
chr11: 117355376
DSCAML1.GENEBODY
SCLC-A
F
chr11: 117352691-
S_Shelf







117352961


cg13290371
chr7: 5518071
FBXL18.UTR3
SCLC-A
R
chr7: 5521368-5521615
N_Shelf


cg13948413
chr1: 236687580
LGALS8.UTR5
SCLC-A
F
chr1: 236687071-
Island







236687608


cg14186816
chr18: 55862763
NEDD4L.UTR5
SCLC-A
F
chr18: 55862653-
Island







55862873


cg15027294
chr12: 1609537
LOC100292680.TSS200
SCLC-A
R


cg15962197
chr1: 41704561
SCMH1.UTR5
SCLC-A
R
chr1: 41706957-
N_Shelf







41708327


cg17097293
chr19: 3655825
PIP5K1C.GENEBODY
SCLC-A
F
chr19: 3659641-3659949
N_Shelf


cg18993457
chr11: 441983
ANO9.UTR5
SCLC-A
R


cg19680850
chr1: 37943106
ZC3H12A.GENEBODY
SCLC-A
F
chr1: 37939723-
S_Shelf







37940650


cg21464975
chr17: 60828260
MARCH10.GENEBODY
SCLC-A
R


cg21832801
chr11: 107579390
SLN.UTR5
SCLC-A
R


cg22019158
chr1: 27926683
AHDC1.UTR5
SCLC-A
R
chr1: 27929705-
N_Shelf







27930866


cg05212460
chr7: 2149814
MAD1L1.GENEBODY
SCLC-A
R


cg08442823
chr11: 45951803
PHF21A.UTR3
SCLC-A
F


cg11856932
chr12: 53447059
TENC1.UTR5
SCLC-A
F
chr12: 53448008-
N_Shore







53448406


cg13002109
chr3: 124041146
KALRN.GENEBODY
SCLC-A
F


cg13160058
chr8: 26243215
BNIP3L.GENEBODY
SCLC-A
F
chr8: 26240290-
S_Shelf







26241017


cg14914552
chr8: 97340188
PTDSS1.GENEBODY
SCLC-A
R


cg15118447
chr6: 159220343
EZR.GENEBODY
SCLC-A
F


cg18335326
chr6: 30653659
KIAA1949.GENEBODY
SCLC-A
F
chr6: 30654392-
N_Shore







30654934


cg22962041
chr17: 49235043
NME1-
SCLC-A
R
chr17: 49230686-
S_Shelf




NME2.GENEBODY


49231247


cg25619638
chr2: 220310232
SPEG.GENEBODY
SCLC-A
F
chr2: 220309637-
S_Shore







220309893


cg11076275
chr1: 207069654
IL24.TSS1500
SCLC-A
F


cg13808641
chr9: 96006533
WNK2.GENEBODY
SCLC-A
R
chr9: 96009844-
N_Shelf







96010101


cg20666533
chr13: 67714028
PCDH9.GENEBODY
SCLC-A
F


cg22311015
chr2: 241630042
AQP12A.TSS1500
SCLC-A
F


cg04671541
chr3: 111717682
TAGLN3.EXON1
SCLC-A
F


cg05712010
chr1: 230895283
CAPN9.GENEBODY
SCLC-A
R


cg06488150
chr7: 6476003
DAGLB.GENEBODY
SCLC-A
F


cg07251887
chr17: 73641809
LOC100130933.TSS15
SCLC-A
R




00


cg08969344
chr6: 34031597
GRM4.GENEBODY
SCLC-A
R


cg09537448
chr7: 129414567
MIR96.GENEBODY
SCLC-A
F
chr7: 129418286-
N_Shelf







129422509


cg18171392
chr22: 24938255
C22orf13.UTR3
SCLC-A
F


cg20951539
chr6: 36367819
PXT1.GENEBODY
SCLC-A
R


cg21635706
chr15: 69432565
MIR548H4.GENEBODY
SCLC-A
R


cg22226592
chr1: 109439213
GPSM2.GENEBODY
SCLC-A
F


cg23375717
chr11: 20883318
NELL1.GENEBODY
SCLC-A
F


cg25670451
chr12: 6487677
SCNN1A.TSS1500
SCLC-A
R


cg00010853
chr6: 30653167
KIAA1949.GENEBODY
SCLC-A
F
chr6: 30654392-
N_Shore







30654934


cg09901733
chr17: 1731852
RPA1.TSS1500
SCLC-A
R
chr17: 1732834-1733612
N_Shore


cg15245625
chr18: 55862676
NEDD4L.UTR5
SCLC-A
R
chr18: 55862653-
Island







55862873


cg16640855
chr2: 182543233
NEUROD1.GENEBODY
SCLC-A
R


cg22047469
chr1: 1110107
TTLL10.UTR5
SCLC-A
R
chr1: 1109314-1110145
Island


cg22468751
chr6: 136824489
MAP7.GENEBODY
SCLC-A
F


cg12299554
chr15: 94840953
MCTP2.TSS1500
SCLC-A
R


cg22169990
chr7: 150786051
AGAP3.GENEBODY
SCLC-A
F
chr7: 150783480-
S_Shore







150785040


cg23286081
chr10: 125775778
CHST15.GENEBODY
SCLC-A
R


cg24750887
chr4: 89534723
HERC3.GENEBODY
SCLC-A
R


cg12473285
chr17: 41832975
SOST.GENEBODY
SCLC-A
R
chr17: 41832717-
Island







41833195


cg00005437
chr17: 18010740
DRG2.UTR3
SCLC-A
F


cg01132785
chr4: 528175
PIGG.GENEBODY
SCLC-A
F
chr4: 529166-529556
N_Shore


cg02124184
chr5: 72950691
RGNEF.UTR5
SCLC-A
F


cg04479757
chr22: 26951319
MIR548J.TSS200
SCLC-A
R


cg05940240
chr22: 41762302
TEF.TSS1500
SCLC-A
F


cg07096883
chr7: 149979234
ACTR3C.GENEBODY
SCLC-A
R


cg08196842
chr14: 65016517
C14orf50.TSS200
SCLC-A
R
chr14: 65016516-
Island







65016909


cg08841552
chr9: 140444378
PNPLA7.GENEBODY
SCLC-A
F
chr9: 140445653-
N_Shore







140446891


cg10206969
chr7: 5518392
FBXL18.UTR3
SCLC-A
F
chr7: 5521368-5521615
N_Shelf


cg12941836
chr3: 52869288
MUSTN1.TSS200
SCLC-A
F


cg19254163
chr11: 60623782
GPR44.TSS1500
SCLC-A
R
chr11: 60619924-
S_Shelf







60621111


cg20465143
chr8: 144653962
C8orf73.GENEBODY
SCLC-A
F
chr8: 144653774-
Island







144653976


cg21563471
chr2: 158184535
ERMN.TSS1500
SCLC-A
R


cg27412310
chr11: 75146692
GDPD5.GENEBODY
SCLC-A
R


cg07414392
chr9: 71735648
TJP2.TSS1500
SCLC-A
R
chr9: 71736074-
N_Shore







71737367


cg07170253
chr12: 48119903
P11.TSS1500
SCLC-A
R


cg13568213
chr9: 136387235
TMEM8C.GENEBODY
SCLC-A
F


cg14770958
chr3: 111717793
TAGLN3.EXON1
SCLC-A
R


cg26068911
chr5: 89967277
GPR98.GENEBODY
SCLC-A
F


cg27281690
chr2: 7171963
RNF144A.GENEBODY
SCLC-A
F
chr2: 7172296-7172512
N_Shore


cg02482603
chr1: 174843754
RABGAP1L.TSS1500
SCLC-A
F


cg05380808
chr1: 210820877
HHAT.GENEBODY
SCLC-A
R


cg05593510
chr5: 176249224
UNC5A.GENEBODY
SCLC-A
R
chr5: 176244559-
S_Shelf







176245284


cg07505680
chr8: 1933651
KBTBD11.UTR5
SCLC-A
F


cg08539179
chr1: 227915948
LOC100130093.TSS15
SCLC-A
R
chr1: 227916425-
N_Shore




00


227916736


cg10068572
chr10: 35687029
CCNY.GENEBODY
SCLC-A
F


cg10828127
chr21: 41550814
DSCAM.GENEBODY
SCLC-A
R
chr21: 41554618-
N_Shelf







41554959


cg11065015
chr20: 327170
NRSN2.TSS200
SCLC-A
R
chr20: 327376-328977
N_Shore


cg15554875
chr2: 45236686
SIX2.TSS200
SCLC-A
F
chr2: 45235511-
Island







45237792


cg24092939
chr12: 49181056
ADCY6.UTR5
SCLC-A
F
chr12: 49182421-
N_Shore







49182658


cg24321971
chr11: 27406919
LGR4.GENEBODY
SCLC-A
R


cg21887193
chr7: 150786082
AGAP3.GENEBODY
SCLC-A
F
chr7: 150783480-
S_Shore







150785040


cg02108198
chr7: 99527876
GJC3.TSS1500
SCLC-A
F


cg05081953
chr2: 158184543
ERMN.TSS1500
SCLC-A
F


cg09717545
chr19: 917707
KISS1R.EXON1
SCLC-A
R
chr19: 917034-920787
Island


cg11104313
chr3: 111717534
TAGLN3.TSS200
SCLC-A
F


cg11672757
chr2: 241080172
OTOS.TSS200
SCLC-A
R


cg14755690
chr7: 128868265
AHCYL2.GENEBODY
SCLC-A
R
chr7: 128864320-
S_Shelf







128865655


cg15169077
chr6: 46139019
ENPP5.TSS1500
SCLC-A
F


cg17476271
chr11: 128562408
FLI1.TSS1500
SCLC-A
F
chr11: 128562671-
N_Shore







128565011


cg24522085
chr2: 169556419
LASS6.GENEBODY
SCLC-A
F


cg04245402
chr19: 751241
C19orf21.UTR5
SCLC-A
R


cg04785838
chr6: 30181742
TRIM26.TSS1500
SCLC-A
F
chr6: 30180933-
Island







30182187


cg06400704
chr1: 240256644
FMN2.EXON1
SCLC-A
F
chr1: 240254959-
Island







240257063


cg08200404
chr15: 62359539
C2CD4A.UTR5
SCLC-A
F
chr15: 62359827-
N_Shore







62360995


cg08529481
chr1: 36832173
STK40.UTR5
SCLC-A
F


cg10245608
chr9: 92221282
GADD45G.UTR3
SCLC-A
R
chr9: 92219771-
Island







92221411


cg17838427
chr1: 204653956
LRRN2.UTR5
SCLC-A
F
chr1: 204654132-
N_Shore







204654885


cg19786648
chr17: 71824806
C17orf54.TSS200
SCLC-A
R


cg21068094
chr18: 55862711
NEDD4L.UTR5
SCLC-A
R
chr18: 55862653-
Island







55862873


cg04994773
chr1: 109656777
KIAA1324.UTR5
SCLC-A
R
chr1: 109656095-
S_Shore







109656611


cg06011067
chr6: 110677913
C6orf186.GENEBODY
SCLC-A
R
chr6: 110678854-
N_Shore







110679108


cg07562888
chr10: 80883720
ZMIZ1.UTR5
SCLC-A
F


cg10598711
chr5: 72470395
TMEM174.UTR3
SCLC-A
R


cg10976861
chr2: 239149937
HES6.TSS1500
SCLC-A
F
chr2: 239147592-
S_Shore







239149900


cg12417176
chr15: 55788778
DYX1C1.GENEBODY
SCLC-A
F
chr15: 55790301-
N_Shore







55790754


cg13284574
chr1: 6519923
ESPN.GENEBODY
SCLC-A
F
chr1: 6520584-6521955
N_Shore


cg16638385
chr17: 41832753
SOST.GENEBODY
SCLC-A
R
chr17: 41832717-
Island







41833195


cg21738316
chrX: 153688775
PLXNA3.GENEBODY
SCLC-A
F
chrX: 153688592-
Island







153688860


cg22618164
chr12: 122356400
WDR66.TSS200
SCLC-A
F
chr12: 122356315-
Island







122356853


cg22626525
chr1: 20008900
TMCO4.UTR3
SCLC-A
F
chr1: 20005510-
S_Shelf







20005865


cg23956760
chr19: 19178708
SLC25A42.UTR5
SCLC-A
R
chr19: 19174262-
S_Shelf







19174995


cg24352878
chr1: 8772712
RERE.UTR5
SCLC-A
R


cg27654966
chr7: 101558400
CUX1.GENEBODY
SCLC-A
R
chr7: 101559402-
N_Shore







101559625


cg04415689
chr2: 242128250
ANO7.GENEBODY
SCLC-A
F


cg07028869
chr12: 49741164
DNAJC22.UTR5
SCLC-A
R
chr12: 49738680-
S_Shore







49740841


cg07354371
chr1: 43736391
TMEM125.UTR5
SCLC-A
R
chr1: 43738484-
N_Shelf







43738829


cg07637741
chr6: 159084426
SYTL3.GENEBODY
SCLC-A
F


cg09833249
chr12: 103312819
PAH.TSS1500
SCLC-A
R
chr12: 103311040-
S_Shore







103311253


cg11545871
chr6: 33679895
C6orf125.TSS1500
SCLC-A
R
chr6: 33679158-
S_Shore







33679701


cg13714797
chr9: 7103479
KDM4C.GENEBODY
SCLC-A
R


cg22504528
chr22: 26951369
MIR548J.TSS200
SCLC-A
F


cg23971638
chr12: 741507
NINJ2.GENEBODY
SCLC-A
R


cg24204017
chr3: 57999988
FLNB.GENEBODY
SCLC-A
F


cg26017492
chr6: 166891729
RPS6KA2.GENEBODY
SCLC-A
F


cg00369376
chr2: 182542510
NEUROD1.UTR3
SCLC-A
F


cg02864954
chr6: 154535553
IPCEF1.GENEBODY
SCLC-A
R


cg03505501
chr11: 115371789
CADM1.GENEBODY
SCLC-A
R
chr11: 115373574-
N_Shore







115375881


cg04886060
chr16: 82044788
SDR42E1.UTR5
SCLC-A
F
chr16: 82044886-
N_Shore







82045306


cg05161682
chr13: 111107167
COL4A2.GENEBODY
SCLC-A
R
chr13: 111109139-
N_Shore







111109652


cg09427605
chr4: 146740968
ZNF827.GENEBODY
SCLC-A
R


cg13396830
chr6: 30181581
TRIM26.TSS1500
SCLC-A
R
chr6: 30180933-
Island







30182187


cg16427420
chr17: 74526161
CYGB.GENEBODY
SCLC-A
F


cg16931969
chr4: 113985495
ANK2.GENEBODY
SCLC-A
F


cg24652919
chr16: 3073191
HCFC1R1.GENEBODY
SCLC-A
R
chr16: 3073686-3074443
N_Shore


cg26504422
chr19: 44277951
KCNN4.GENEBODY
SCLC-A
R
chr19: 44278273-
N_Shore







44278777


cg06537333
chr16: 85643863
KIAA0182.TSS1500
SCLC-A
F
chr16: 85644089-
N_Shore







85644323


cg10156302
chr15: 64202084
DAPK2.GENEBODY
SCLC-A
F


cg13866253
chr11: 77093001
PAK1.GENEBODY
SCLC-A
R


cg14052044
chr19: 751159
C19orf21.EXON1
SCLC-A
R
chr19: 746300-747161
S_Shelf


cg14465207
chr2: 10951250
PDIA6.GENEBODY
SCLC-A
F
chr2: 10952402-
N_Shore







10953384


cg14695840
chr9: 71737258
TJP2.UTR5
SCLC-A
R
chr9: 71736074-
Island







71737367


cg16832421
chr2: 122229878
CLASP1.GENEBODY
SCLC-A
F


cg18070562
chr17: 8013617
ALOXE3.GENEBODY
SCLC-A
R
chr17: 8013172-8013657
Island


cg20592124
chr2: 65290738
CEP68.UTR5
SCLC-A
R


cg25736482
chr19: 54677232
MBOAT7.UTR3
SCLC-A
R


cg27417294
chr10: 81904244
PLAC9.GENEBODY
SCLC-A
R


cg27536453
chr3: 169530417
LRRC34.TSS200
SCLC-A
F
chr3: 169529875-
Island







169530435


cg01248385
chr13: 113636953
MCF2L.GENEBODY
SCLC-A
R
chr13: 113635654-
S_Shore







113635899


cg03646740
chr13: 114813015
RASA3.GENEBODY
SCLC-A
R
chr13: 114813942-
N_Shore







114814457


cg08641990
chr1: 54822503
SSBP3.GENEBODY
SCLC-A
F
chr1: 54821990-
S_Shore







54822333


cg11482099
chr11: 31833477
PAX6.TSS1500
SCLC-A
F
chr11: 31831620-
Island







31839038


cg14864994
chr12: 6496214
LTBR.GENEBODY
SCLC-A
F
chr12: 6492889-6493522
S_Shelf


cg16681516
chr19: 46297285
DMWD.TSS1500
SCLC-A
R
chr19: 46295855-
S_Shore







46296347


cg18998911
chr3: 111718245
TAGLN3.EXON1
SCLC-A
R


cg20679581
chr8: 10222777
MSRA.GENEBODY
SCLC-A
F


cg24904739
chr17: 77959804
TBC1D16.GENEBODY
SCLC-A
R


cg25193885
chr11: 70328867
SHANK2.GENEBODY
SCLC-A
F
chr11: 70332266-
N_Shelf







70333413


cg03127370
chr16: 2520192
NTN3.TSS1500
SCLC-A
R
chr16: 2521086-2525929
N_Shore


cg12668122
chr3: 133094221
TMEM108.GENEBODY
SCLC-A
R


cg17749454
chr17: 73101934
SLC16A5.GENEBODY
SCLC-A
R
chr17: 73105229-
N_Shelf







73106667


cg21972567
chr5: 158350708
EBF1.GENEBODY
SCLC-A
F


cg25076197
chr7: 104681440
MLL5.GENEBODY
SCLC-A
F


cg26534460
chr2: 215896959
ABCA12.TSS200
SCLC-A
F


cg15723222
chr17: 59222476
BCAS3.GENEBODY
SCLC-A
R


cg19420604
chr17: 60828406
MARCH10.GENEBODY
SCLC-A
F


cg02449373
chr19: 49256123
FUT1.UTR5
SCLC-A
F
chr19: 49255778-
Island







49256495


cg03467001
chr1: 183857649
RGL1.GENEBODY
SCLC-A
R


cg03751944
chr19: 1081936
HMHA1.GENEBODY
SCLC-A
F
chr19: 1079682-1081937
Island


cg04220881
chr7: 152524814
ACTR3B.GENEBODY
SCLC-A
F


cg05251389
chr22: 43525330
BIK.UTR3
SCLC-A
F


cg13520715
chr21: 43135854
C21orf129.GENEBODY
SCLC-A
R


cg15559684
chr3: 63428234
SYNPR.GENEBODY
SCLC-A
R


cg19272238
chr17: 76220898
BIRC5.UTR3
SCLC-A
F


cg20628733
chr1: 3524459
MEGF6.GENEBODY
SCLC-A
R
chr1: 3527619-3528078
N_Shelf


cg26985681
chr16: 15135397
NTAN1.GENEBODY
SCLC-A
F


cg27274706
chr11: 129685751
TMEM45B.EXON1
SCLC-A
R
chr11: 129685737-
Island







129686211


cg04930469
chr17: 41832882
SOST.GENEBODY
SCLC-A
R
chr17: 41832717-
Island







41833195


cg09853822
chr17: 4712456
PLD2.GENEBODY
SCLC-A
F
chr17: 4710014-4710960
S_Shore


cg15460454
chr7: 1974654
MAD1L1.GENEBODY
SCLC-A
R
chr7: 1976258-1976464
N_Shore


cg22532234
chr19: 40229215
CLC.TSS1500
SCLC-A
R


cg04746649
chr2: 169401301
LASS6.GENEBODY
SCLC-A
R


cg09540626
chr16: 2590751
PDPK1.GENEBODY
SCLC-A
F
chr16: 2588034-2588556
S_Shelf


cg22244768
chr17: 55634551
MSI2.GENEBODY
SCLC-A
F


cg26504421
chr17: 71339361
SDK2.GENEBODY
SCLC-A
R


cg06839900
chr1: 2461900
HES5.TSS1500
SCLC-A
R
chr1: 2460760-2462010
Island


cg03091070
chr6: 169641288
THBS2.GENEBODY
SCLC-A
R
chr6: 169641803-
N_Shore







169642020


cg14260458
chr7: 97620123
OCM2.TSS1500
SCLC-A
R


cg17852245
chr5: 153688187
GALNT10.GENEBODY
SCLC-A
F


cg19974120
chr21: 42839625
TMPRSS2.GENEBODY
SCLC-A
F


cg20141509
chr1: 10781431
CASZ1.UTR5
SCLC-A
F


cg25438492
chr6: 33079692
HLA-DPB2.TSS1500
SCLC-A
F


cg26344024
chr3: 71357195
FOXP1.UTR5
SCLC-A
R


cg27126442
chr4: 106473806
FLJ20184.UTR5
SCLC-A
F


cg03018001
chr19: 751098
C19orf21.TSS200
SCLC-A
R
chr19: 746300-747161
S_Shelf


cg01132579
chr17: 55588940
MSI2.GENEBODY
SCLC-A
R


cg03029090
chr15: 58812960
LIPC.GENEBODY
SCLC-A
R


cg06694239
chr7: 128807764
TSPAN33.UTR3
SCLC-A
F
chr7: 128809089-
N_Shore







128809393


cg08253704
chr6: 30653242
KIAA1949.GENEBODY
SCLC-A
R
chr6: 30654392-
N_Shore







30654934


cg08702745
chr13: 111138063
COL4A2.GENEBODY
SCLC-A
R


cg13793782
chr9: 135995093
RALGDS.GENEBODY
SCLC-A
F
chr9: 135995969-
N_Shore







135996954


cg15925940
chr14: 105330630
KIAA0284.TSS1500
SCLC-A
R
chr14: 105330514-
Island







105332186


cg18612589
chr17: 7165847
CLDN7.TSS200
SCLC-A
R
chr17: 7164285-7166245
Island


cg20831413
chr11: 72460551
ARAP1.UTR5
SCLC-A
R
chr11: 72463092-
N_Shelf







72463717


cg12248883
chr11: 6219573
OR52W1.TSS1500
SCLC-A
F


cg00300637
chr5: 319433
AHRR.GENEBODY
SCLC-A
R
chr5: 320788-323010
N_Shore


cg01661001
chr20: 44439932
UBE2C.TSS1500
SCLC-A
F
chr20: 44440946-
N_Shore







44441655


cg02394998
chr7: 157334850
PTPRN2.GENEBODY
SCLC-A
R


cg04260891
chr7: 75514575
RHBDD2.GENEBODY
SCLC-A
F


cg12686273
chr16: 3085867
CCDC64B.TSS1500
SCLC-A
F
chr16: 3086283-3086968
N_Shore


cg13363823
chr1: 40362907
MYCL1.UTR3
SCLC-A
F
chr1: 40366595-
N_Shelf







40368213


cg13401831
chr22: 18593307
TUBA8.TSS1500
SCLC-A
R
chr22: 18593113-
Island







18594197


cg20234170
chr11: 34460107
CAT.TSS1500
SCLC-A
F
chr11: 34460165-
N_Shore







34460857


cg22481263
chr1: 906493
PLEKHN1.GENEBODY
SCLC-A
R
chr1: 906296-906538
Island


cg24688343
chr17: 61229244
TANC2.GENEBODY
SCLC-A
F


cg13844853
chr1: 94062769
BCAR3.GENEBODY
SCLC-A
F


cg20505457
chr14: 69388953
ACTN1.GENEBODY
SCLC-A
F


cg02923393
chr16: 1543003
TELO2.TSS1500
SCLC-A
R
chr16: 1543098-1544426
N_Shore


cg03021329
chr3: 124554058
ITGB5.GENEBODY
SCLC-A
F


cg07720856
chr2: 232572668
PTMA.TSS1500
SCLC-A
F
chr2: 232571137-
Island







232575833


cg10708739
chr17: 57465550
YPEL2.GENEBODY
SCLC-A
F


cg12296860
chr11: 46409428
CHRM4.TSS1500
SCLC-A
R
chr11: 46410921-
N_Shore







46414687


cg15602548
chr2: 54786148
SPTBN1.GENEBODY
SCLC-A
F
chr2: 54785026-
S_Shore







54785969


cg20925462
chr3: 111717806
TAGLN3.TSS200
SCLC-A
R


cg21055933
chr14: 64682702
SYNE2.EXON1
SCLC-A
F


cg24791666
chr3: 39192215
CSRNP1.UTR5
SCLC-A
F
chr3: 39194241-
N_Shelf







39195359


cg00078299
chr8: 124284379
ZHX1.UTR5
SCLC-A
R
chr8: 124286209-
N_Shore







124287666


cg00474798
chr2: 84684489
SUCLG1.GENEBODY
SCLC-A
R
chr2: 84686005-
N_Shore







84686751


cg00510447
chr16: 3071608
TNFRSF12A.GENEBODY
SCLC-A
F
chr16: 3070095-3071305
S_Shore


cg00959749
chr1: 54302681
TMEM48.GENEBODY
SCLC-A
F
chr1: 54303758-
N_Shore







54304262


cg01267165
chr16: 11681599
LITAF.TSS1500
SCLC-A
F
chr16: 11680008-
S_Shore







11681275


cg02405813
chr6: 83072522
TPBG.TSS1500
SCLC-A
F
chr6: 83073416-
N_Shore







83075319


cg06665622
chr6: 46293571
RCAN2.TSS200
SCLC-A
F


cg07460919
chr3: 183980626
ECE2.GENEBODY
SCLC-A
R
chr3: 183977548-
Island







183980633


cg08869273
chr11: 413594
SIGIRR.UTR5
SCLC-A
R
chr11: 416419-417650
N_Shelf


cg09238199
chr13: 111097777
COL4A2.GENEBODY
SCLC-A
F


cg09333109
chr19: 51532580
KLK11.TSS1500
SCLC-A
F
chr19: 51535218-
N_Shelf







51535475


cg10813585
chr1: 114305956
RSBN1.UTR3
SCLC-A
R
chr1: 114301514-
S_Shelf







114302272


cg11243251
chr6: 36209708
PNPLA1.TSS1500
SCLC-A
R


cg14194715
chr13: 32651552
FRY.GENEBODY
SCLC-A
F


cg01262667
chr19: 19385393
TM6SF2.TSS1500
SCLC-A
F
chr19: 19383703-
S_Shore







19384283


cg03581459
chr14: 105780137
PACS2.TSS1500
SCLC-A
F
chr14: 105780339-
N_Shore







105782027


cg04961866
chr16: 3085686
CCDC64B.TSS200
SCLC-A
R
chr16: 3086283-3086968
N_Shore


cg05263838
chr2: 227659406
IRS1.UTR3
SCLC-A
F
chr2: 227662082-
N_Shelf







227664912


cg05962028
chr12: 214000
IQSEC3.GENEBODY
SCLC-A
F
chr12: 213763-214227
Island


cg11908131
chr2: 106685045
C2orf40.GENEBODY
SCLC-A
R
chr2: 106681982-
S_Shelf







106682403


cg14245347
chr6: 29856426
HLA-H.GENEBODY
SCLC-A
R
chr6: 29855295-
Island







29856565


cg14377791
chr19: 40169912
LOC400696.TSS200
SCLC-A
F


cg16081441
chr17: 74463560
AANAT.TSS200
SCLC-A
R


cg17889402
chr18: 55862872
NEDD4L.UTR5
SCLC-A
F
chr18: 55862653-
Island







55862873


cg20169296
chr10: 103367727
RP11-
SCLC-A
R




529I cg0076479610.4.GENEBODY


cg05554594
chr17: 80584498
WDR45L.GENEBODY
SCLC-A
F


cg06915226
chr2: 70960959
ADD2.UTR5
SCLC-A
F


cg07121199
chr1: 205537752
MFSD4.TSS1500
SCLC-A
R
chr1: 205537751-
Island







205538443


cg16929041
chr17: 26648951
TMEM97.GENEBODY
SCLC-A
F
chr17: 26645290-
S_Shelf







26645614


cg21521758
chr7: 150036287
RARRES2.GENEBODY
SCLC-A
F
chr7: 150037459-
N_Shore







150039031


cg00282244
chr7: 100876136
CLDN15.GENEBODY
SCLC-A
F
chr7: 100875555-
Island







100876212


cg01062519
chr17: 34122169
MMP28.GENEBODY
SCLC-A
F
chr17: 34122024-
Island







34122801


cg01796143
chr1: 236687575
LGALS8.UTR5
SCLC-A
R
chr1: 236687071-
Island







236687608


cg01897496
chr2: 182545209
NEUROD1.EXON1
SCLC-A
R
chr2: 182547873-
N_Shelf







182549177


cg02445907
chr6: 36294404
C6orf222.GENEBODY
SCLC-A
F


cg10351284
chr8: 125617225
MTSS1.GENEBODY
SCLC-A
F


cg12778007
chr14: 72041267
SIPA1L1.UTR5
SCLC-A
F


cg13302994
chr2: 210714233
UNC80.GENEBODY
SCLC-A
F


cg16341266
chr7: 147256367
MIR54814.TSS1500
SCLC-A
F


cg17265693
chr17: 7166490
CLDN7.TSS1500
SCLC-A
F
chr17: 7164285-7166245
S_Shore


cg17956387
chr1: 208418015
PLXNA2.TSS1500
SCLC-A
R
chr1: 208416489-
Island







208418016


cg18319790
chr14: 100788777
C14orf68.TSS1500
SCLC-A
R


cg21719937
chr12: 5564478
NTF3.GENEBODY
SCLC-A
R


cg21740204
chr9: 72873544
SMC5.TSS1500
SCLC-A
F
chr9: 72873689-
N_Shore







72874264


cg24657047
chr15: 77317370
PSTPIP1.GENEBODY
SCLC-A
R
chr15: 77320150-
N_Shelf







77320456


cg26037504
chr12: 56113808
RDH5.TSS1500
SCLC-A
F
chr12: 56109798-
S_Shelf







56110298


cg26782539
chr10: 134061662
STK32C.GENEBODY
SCLC-A
F


cg02010776
chr16: 18938091
SMG1.TSS1500
SCLC-A
R
chr16: 18937030-
Island







18938126


cg03920522
chr7: 94047477
COL1A2.GENEBODY
SCLC-A
R


cg08946575
chr1: 85931072
DDAH1.TSS200
SCLC-A
F
chr1: 85929940-
Island







85931168


cg10039567
chr1: 112395111
KCND3.GENEBODY
SCLC-A
R


cg10316635
chr1: 62208645
INADL.UTR5
SCLC-A
R
chr1: 62207827-
Island







62208818


cg12930882
chr5: 37825585
GDNF.GENEBODY
SCLC-A
R


cg13973639
chr6: 42858710
C6orf226.TSS200
SCLC-A
R
chr6: 42858169-
Island







42858960


cg15653828
chr6: 34513187
SPDEF.UTR5
SCLC-A
F
chr6: 34512063-
S_Shore







34512266


cg19153095
chr8: 106811143
ZFPM2.GENEBODY
SCLC-A
F


cg26335620
chr19: 48215149
EHD2.TSS1500
SCLC-A
F
chr19: 48216486-
N_Shore







48216837


cg11356571
chr19: 48219924
EHD2.GENEBODY
SCLC-A
R
chr19: 48219831-
Island







48220298


cg02531277
chr7: 101558597
CUX1.GENEBODY
SCLC-A
R
chr7: 101559402-
N_Shore







101559625


cg02565999
chr13: 95003984
GPC6.GENEBODY
SCLC-A
F


cg03036777
chr1: 33648819
TRIM62.TSS1500
SCLC-A
F
chr1: 33646613-
S_Shore







33647878


cg03469805
chr14: 105330648
KIAA0284.TSS1500
SCLC-A
F
chr14: 105330514-
Island







105332186


cg03621100
chr12: 104322919
LOC253724.GENEBODY
SCLC-A
F
chr12: 104323017-
N_Shore







104324811


cg04608356
chr1: 27668433
SYTL1.TSS200
SCLC-A
R


cg06644669
chr6: 30653799
KIAA1949.UTR5
SCLC-A
R
chr6: 30654392-
N_Shore







30654934


cg08706567
chr1: 43814983
MPL.GENEBODY
SCLC-A
F
chr1: 43814305-
Island







43815277


cg08905114
chr9: 95897015
NINJ1.TSS1500
SCLC-A
R
chr9: 95896007-
Island







95897016


cg09702010
chr19: 51531393
KLK11.TSS1500
SCLC-A
F
chr19: 51535218-
N_Shelf







51535475


cg09865760
chr12: 49739893
DNAJC22.TSS1500
SCLC-A
R
chr12: 49738680-
Island







49740841


cg13264672
chr7: 39993440
CDK13.GENEBODY
SCLC-A
F
chr7: 39988922-
S_Shore







39991612


cg14607161
chr6: 32084298
ATF6B.GENEBODY
SCLC-A
R


cg17141902
chr9: 95897216
NINJ1.TSS1500
SCLC-A
F
chr9: 95896007-
S_Shore







95897016


cg26681687
chr4: 77874155
SEPT11.GENEBODY
SCLC-A
F
chr4: 77869440-
S_Shelf







77872122


cg02512352
chr7: 151137048
CRYGN.EXON1
SCLC-A
F
chr7: 151136933-
Island







151137273


cg05098417
chr11: 64067858
C11orf20.TSS200
SCLC-A
F
chr11: 64066757-
Island







64068741


cg05155047
chr5: 168719
PLEKHG4B.GENEBODY
SCLC-A
F
chr5: 169578-169798
N_Shore


cg06740893
chr1: 12251869
TNFRSF1B.GENEBODY
SCLC-A
R
chr1: 12251777-
Island







12251985


cg07065666
chr6: 167034653
RPS6KA2.GENEBODY
SCLC-A
R
chr6: 167032330-
S_Shelf







167032582


cg10754794
chr10: 93916288
CPEB3.GENEBODY
SCLC-A
F


cg12934258
chr6: 159084599
SYTL3.GENEBODY
SCLC-A
F


cg15744692
chr15: 45671195
LOC145663.GENEBODY
SCLC-A
F
chr15: 45669970-
S_Shore







45671029


cg21604615
chr1: 27668610
SYTL1.EXON1
SCLC-A
F


cg00955867
chr1: 160337038
NHLH1.EXON1
SCLC-A
R
chr1: 160340604-
N_Shelf







160340843


cg01470599
chr9: 38422794
IGFBPL1.GENEBODY
SCLC-A
F
chr9: 38423947-
N_Shore







38424584


cg01562385
chr19: 10698098
AP1M2.TSS200
SCLC-A
R
chr19: 10697786-
Island







10698099


cg06508379
chr19: 19104064
SFRS14.UTR3
SCLC-A
R


cg07491702
chr15: 43030817
CDAN1.TSS1500
SCLC-A
R
chr15: 43028413-
S_Shore







43029346


cg08673532
chr16: 87422913
FBXO31.GENEBODY
SCLC-A
F
chr16: 87425137-
N_Shelf







87426677


cg16320329
chr3: 45981161
FYCO1.GENEBODY
SCLC-A
F


cg16321266
chr7: 129414894
MIR183.TSS200
SCLC-A
F
chr7: 129418286-
N_Shelf







129422509


cg17033622
chr11: 128568943
FLI1.GENEBODY
SCLC-A
R
chr11: 128562671-
S_Shelf







128565011


cg17420360
chr12: 49740840
DNAJC22.TSS200
SCLC-A
F
chr12: 49738680-
Island







49740841


cg18911861
chr6: 42858743
C6orf226.TSS200
SCLC-A
R
chr6: 42858169-
Island







42858960


cg19599803
chr1: 156722676
HDGF.TSS1500
SCLC-A
F
chr1: 156720747-
S_Shore







156722069


cg22791543
chr5: 127416532
FLJ33630.GENEBODY
SCLC-A
R
chr5: 127418594-
N_Shelf







127420512


cg26020521
chr11: 8680436
TRIM66.TSS200
SCLC-A
F


cg26877508
chr15: 71495324
THSD4.GENEBODY
SCLC-A
R


cg27360567
chr3: 49941613
MST1R.TSS1500
SCLC-A
F
chr3: 49940099-
S_Shore







49940431


cg00764796
chr16: 433504
LOC100134368.GENEBODY
SCLC-A
R
chr16: 431189-432810
S_Shore


cg05305327
chr20: 32156436
CBFA2T2.GENEBODY
SCLC-A
R


cg08843859
chr1: 184566345
C1orf21.GENEBODY
SCLC-A
F


cg09027133
chr1: 25945042
MAN1C1.GENEBODY
SCLC-A
F
chr1: 25942661-
S_Shore







25943191


cg12145018
chr14: 103912507
MARK3.GENEBODY
SCLC-A
F


cg14087413
chr9: 35848330
TMEM8B.GENEBODY
SCLC-A
R
chr9: 35846310-
S_Shore







35846638


cg18449361
chr6: 2689154
MYLK4.GENEBODY
SCLC-A
R
chr6: 2685400-2685625
S_Shelf


cg22393461
chr1: 10010658
NMNAT1.UTR5
SCLC-A
F


cg23365482
chr15: 40764195
CHST14.EXON1
SCLC-A
F
chr15: 40763162-
Island







40764196


cg22572454
chr17: 74463767
AANAT.GENEBODY
SCLC-A
F


cg00034154
chr19: 10337163
S1PR2.UTR5
SCLC-A
F
chr19: 10334618-
S_Shore







10335511


cg03738134
chr8: 144653855
C8orf73.GENEBODY
SCLC-A
R
chr8: 144653774-
Island







144653976


cg04656424
chr16: 88839844
FAM38A.GENEBODY
SCLC-A
F
chr16: 88838112-
S_Shore







88838459


cg06561646
chr17: 35873369
DUSP14.UTR3
SCLC-A
F
chr17: 35872722-
S_Shore







35873026


cg07119973
chr17: 43109221
DCAKD.GENEBODY
SCLC-A
R
chr17: 43111525-
N_Shelf







43111732


cg07920930
chr7: 158381884
PTPRN2.TSS1500
SCLC-A
R
chr7: 158379328-
S_Shore







158381221


cg08637583
chr15: 44828465
EIF3J.TSS1500
SCLC-A
R
chr15: 44828637-
N_Shore







44829949


cg14453201
chr5: 320888
AHRR.GENEBODY
SCLC-A
R
chr5: 320788-323010
Island


cg15507486
chr19: 46627896
IGFL3.EXON1
SCLC-A
F


cg17236870
chr4: 94122883
GRID2.GENEBODY
SCLC-A
F


cg21093368
chr17: 8055834
PER1.TSS200
SCLC-A
F
chr17: 8054550-8055835
Island


cg26477169
chr17: 75196864
SEC14L1.GENEBODY
SCLC-A
R


cg26692003
chr3: 13063165
IQSEC1.GENEBODY
SCLC-A
R


cg27262398
chr11: 107578793
SLN.UTR5
SCLC-A
R


cg27559097
chr2: 144987743
GTDC1.UTR5
SCLC-A
F


cg12817389
chr8: 62602522
ASPH.GENEBODY
SCLC-A
R


cg18407095
chr2: 26846581
CIB4.GENEBODY
SCLC-A
R


cg08439728
chr6: 31097073
PSORS1C1.UTR5
SCLC-A
F


cg00225157
chr6: 33173038
HSD17B8.GENEBODY
SCLC-A
F
chr6: 33172289-
S_Shore







33172823


cg00648184
chr17: 60828157
MARCH10.GENEBODY
SCLC-A
R


cg01930441
chr16: 21289268
CRYM.GENEBODY
SCLC-A
F
chr16: 21289419-
N_Shore







21289819


cg03035849
chr6: 91003200
BACH2.UTR5
SCLC-A
R
chr6: 91004795-
N_Shore







91006944


cg05294243
chr19: 51569106
KLK13.TSS1500
SCLC-A
F
chr19: 51568154-
S_Shore







51568412


cg05581469
chr12: 49413435
MLL2.UTR3
SCLC-A
F
chr12: 49412299-
S_Shore







49412756


cg05639747
chr12: 49740942
DNAJC22.TSS200
SCLC-A
R
chr12: 49738680-
S_Shore







49740841


cg13296983
chr12: 6436553
PLEKHG6.GENEBODY
SCLC-A
F
chr12: 6438272-6438931
N_Shore


cg25989783
chr8: 102699486
NCALD.UTR3
SCLC-A
F


cg01448470
chr1: 18518226
IGSF21.GENEBODY
SCLC-A
R


cg06747907
chr1: 16091100
FBLIM1.UTR5
SCLC-A
R


cg01864032
chrX: 69674332
DLG3.GENEBODY
SCLC-A
F
chrX: 69674799-
N_Shore







69675305


cg04138378
chr7: 95849192
MIR591.TSS200
SCLC-A
R


cg12503394
chr7: 1596118
TMEM184A.TSS200
SCLC-A
R


cg15152301
chr3: 50425602
CACNA2D2.GENEBODY
SCLC-A
F


cg15787636
chr17: 80866113
TBCD.GENEBODY
SCLC-A
R
chr17: 80863327-
S_Shelf







80863743


cg16884042
chr2: 223289683
SGPP2.GENEBODY
SCLC-A
F
chr2: 223288922-
Island







223290013


cg18535456
chr12: 112203801
ALDH2.TSS1500
SCLC-A
R
chr12: 112204498-
N_Shore







112204979


cg25882455
chr22: 38599073
MAFF.EXON1
SCLC-A
F
chr22: 38597785-
S_Shore







38598988


cg26785346
chr4: 186732936
SORBS2.UTR5
SCLC-A
R


cg01708552
chr7: 100815485
C7orf52.GENEBODY
SCLC-A
R
chr7: 100815484-
Island







100816995


cg02487823
chr3: 197440451
KIAA0226.GENEBODY
SCLC-A
F


cg02862897
chr17: 79793088
DYSFIP1.TSS200
SCLC-A
F
chr17: 79790530-
S_Shore







79791553


cg05036991
chr2: 155089854
GALNT13.GENEBODY
SCLC-A
F


cg13036352
chr6: 30651825
KIAA1949.GENEBODY
SCLC-A
F
chr6: 30654392-
N_Shelf







30654934


cg13478289
chr6: 33132650
COL11A2.GENEBODY
SCLC-A
F
chr6: 33129291-
S_Shelf







33129718


cg13508369
chr9: 129884026
ANGPTL2.UTR5
SCLC-A
R


cg14703553
chr17: 70663493
SLC39A11.GENEBODY
SCLC-A
R


cg15076368
chr3: 39224943
XIRP1.UTR3
SCLC-A
R
chr3: 39222280-
S_Shelf







39222670


cg15204874
chr1: 54822298
SSBP3.GENEBODY
SCLC-A
R
chr1: 54821990-
Island







54822333


cg18010718
chr17: 74075195
ZACN.TSS200
SCLC-A
R
chr17: 74070404-
S_Shore







74073530


cg18211633
chr12: 122205609
TMEM120B.GENEBODY
SCLC-A
R


cg19095827
chr3: 107243066
BBX.UTR5
SCLC-A
F
chr3: 107241845-
S_Shore







107242731


cg19287817
chr19: 15391339
BRD4.TSS200
SCLC-A
F


cg19589800
chr12: 93820263
UBE2N.GENEBODY
SCLC-A
F


cg23350812
chr2: 236415734
AGAP1.GENEBODY
SCLC-A
R


cg00985958
chr6: 71605996
B3GAT2.GENEBODY
SCLC-A
F


cg01033299
chr12: 53601015
ITGB7.TSS200
SCLC-A
R


cg02492946
chr1: 21667630
ECE1.GENEBODY
SCLC-A
R
chr1: 21671360-
N_Shelf







21672319


cg04617549
chr19: 51569622
KLK13.TSS1500
SCLC-A
F
chr19: 51568154-
S_Shore







51568412


cg04918002
chr16: 87423124
FBXO31.GENEBODY
SCLC-A
R
chr16: 87425137-
N_Shelf







87426677


cg05487134
chr17: 40489569
STAT3.GENEBODY
SCLC-A
F


cg05928980
chr1: 29567425
PTPRU.GENEBODY
SCLC-A
R
chr1: 29562745-
S_Shelf







29565307


cg07824564
chr1: 179050911
TOR3A.TSS200
SCLC-A
F
chr1: 179051075-
N_Shore







179051948


cg13261623
chr17: 74462685
AANAT.GENEBODY
SCLC-A
R


cg13698883
chr9: 38422614
IGFBPL1.GENEBODY
SCLC-A
F
chr9: 38423947-
N_Shore







38424584


cg26279814
chr17: 37617607
CDK12.TSS200
SCLC-A
F
chr17: 37617531-
Island







37618045


cg26575738
chr17: 44896168
WNT3.TSS200
SCLC-A
F
chr17: 44895800-
Island







44897025


cg00193613
chr17: 77042810
C1QTNF1.GENEBODY
SCLC-A
R
chr17: 77043741-
N_Shore







77044489


cg00715124
chr6: 3227026
TUBB2B.GENEBODY
SCLC-A
R
chr6: 3227025-3229688
Island


cg03182958
chr2: 223288923
SGPP2.TSS1500
SCLC-A
R
chr2: 223288922-
Island







223290013


cg05650846
chr16: 3078142
CCDC64B.GENEBODY
SCLC-A
R
chr16: 3078141-3078553
Island


cg06201861
chr16: 84877964
CRISPLD2.GENEBODY
SCLC-A
F


cg07985864
chr1: 10757892
CASZ1.UTR5
SCLC-A
R
chr1: 10757891-
Island







10758252


cg10544251
chr1: 156215727
PAQR6.UTR5
SCLC-A
R
chr1: 156215368-
Island







156215899


cg23261073
chr1: 9880771
CLSTN1.GENEBODY
SCLC-A
R
chr1: 9883011-9884667
N_Shelf


cg23551605
chr2: 236442942
AGAP1.GENEBODY
SCLC-A
F
chr2: 236443815-
N_Shore







236444025


cg25482454
chr2: 85988369
ATOH8.GENEBODY
SCLC-A
R


cg03230858
chr19: 751124
C19orf21.TSS200
SCLC-A
R
chr19: 746300-747161
S_Shelf


cg03732014
chr21: 30676184
BACH1.UTR5
SCLC-A
F


cg03880611
chr5: 31889373
PDZD2.GENEBODY
SCLC-A
F


cg06091094
chr11: 44927766
TSPAN18.UTR5
SCLC-A
F


cg10426951
chr1: 54821910
SSBP3.GENEBODY
SCLC-A
F
chr1: 54821990-
N_Shore







54822333


cg16595667
chr14: 77567533
KIAA1737.UTR5
SCLC-A
F
chr14: 77563965-
S_Shelf







77564697


cg17490445
chr7: 32623673
AVL9.UTR3
SCLC-A
F


cg17699214
chr4: 40890013
APBB2.GENEBODY
SCLC-A
R


cg21094405
chr13: 113656117
MCF2L.GENEBODY
SCLC-A
R
chr13: 113656116-
Island







113656379


cg22807241
chr7: 147709862
MIR548F3.GENEBODY
SCLC-A
R


cg24837219
chr3: 132772692
TMEM108.UTR5
SCLC-A
R


cg27630771
chr1: 150533123
ADAMTSL4.UTR3
SCLC-A
R
chr1: 150534075-
N_Shore







150534301


cg00564723
chr10: 75632066
CAMK2G.GENEBODY
SCLC-A
F
chr10: 75633600-
N_Shore







75634796


cg01100330
chr22: 39639518
PDGFB.GENEBODY
SCLC-A
R
chr22: 39638219-
Island







39640966


cg04999036
chr15: 42566375
TMEM87A.TSS1500
SCLC-A
R
chr15: 42566198-
Island







42566404


cg06130787
chr19: 51523550
KLK10.TSS1500
SCLC-A
F
chr19: 51522004-
S_Shore







51522803


cg07610192
chr2: 131130423
PTPN18.GENEBODY
SCLC-A
R
chr2: 131129718-
Island







131130511


cg09923953
chr19: 51525638
KLK11.UTR3
SCLC-A
F
chr19: 51522004-
S_Shelf







51522803


cg14414406
chr9: 100326029
TMOD1.GENEBODY
SCLC-A
F


cg19392379
chr10: 123909426
TACC2.GENEBODY
SCLC-A
R


cg19477361
chr19: 2607903
GNG7.UTR5
SCLC-A
R
chr19: 2607725-2607967
Island


cg22453183
chr5: 89940953
GPR98.GENEBODY
SCLC-A
F


cg09701233
chr2: 236415814
AGAP1.GENEBODY
SCLC-A
R


cg10585321
chr9: 135995491
RALGDS.GENEBODY
SCLC-A
R
chr9: 135995969-
N_Shore







135996954


cg12581298
chr7: 1080836
C7orf50.GENEBODY
SCLC-A
R
chr7: 1080835-1081069
Island


cg13548543
chr9: 34460044
DNAI1.GENEBODY
SCLC-A
F
chr9: 34457375-
S_Shore







34458892


cg15055890
chr3: 11747650
VGLL4.UTR5
SCLC-A
R
chr3: 11746577-
S_Shore







11746824


cg18322589
chr10: 123909456
TACC2.GENEBODY
SCLC-A
F


cg18814808
chr5: 143698198
KCTD16.GENEBODY
SCLC-A
R


cg19529471
chr13: 35517634
NBEA.GENEBODY
SCLC-A
R


cg25285041
chr1: 41627631
SCMH1.UTR5
SCLC-A
R


cg00664743
chr22: 31300253
OSBP2.GENEBODY
SCLC-A
R
chr22: 31301702-
N_Shore







31302133


cg03717830
chr6: 30182244
TRIM26.TSS1500
SCLC-A
R
chr6: 30180933-
S_Shore







30182187


cg15766101
chr19: 46519228
CCDC61.GENEBODY
SCLC-A
R
chr19: 46518283-
Island







46520080


cg17499826
chr19: 46284986
DMPK.GENEBODY
SCLC-A
F
chr19: 46282544-
S_Shore







46283127


cg18263988
chr3: 111582491
PHLDB2.UTR5
SCLC-A
R
chr3: 111578237-
S_Shelf







111578739


cg21146273
chr5: 152869193
GRIA1.TSS1500
SCLC-A
F


cg22540067
chr2: 125305001
CNTNAP5.GENEBODY
SCLC-A
F


cg02312706
chr16: 87384599
FBXO31.GENEBODY
SCLC-A
F


cg02445972
chr17: 7166593
CLDN7.TSS1500
SCLC-A
R
chr17: 7164285-7166245
S_Shore


cg03762081
chr19: 51523565
KLK10.TSS1500
SCLC-A
F
chr19: 51522004-
S_Shore







51522803


cg14677615
chr17: 27315628
SEZ6.GENEBODY
SCLC-A
R
chr17: 27312969-
S_Shelf







27313283


cg14946113
chr22: 44220872
SULT4A1.UTR3
SCLC-A
F


cg17585356
chr17: 78857121
RPTOR.GENEBODY
SCLC-A
R
chr17: 78857630-
N_Shore







78857866


cg19727124
chr1: 6553227
PLEKHG5.GENEBODY
SCLC-A
R
chr1: 6550083-6551115
S_Shelf


cg23045716
chr4: 1201881
LOC100130872.GENEBODY
SCLC-A
R
chr4: 1202956-1203200
N_Shore


cg23098020
chr1: 153651886
NPR1.EXON1
SCLC-A
F
chr1: 153650830-
Island







153652375


cg24302354
chr19: 48219029
EHD2.UTR5
SCLC-A
R
chr19: 48219831-
N_Shore







48220298


cg26530485
chr1: 23496304
LUZP1.TSS1500
SCLC-A
F


cg27119919
chr11: 60684332
TMEM109.UTR5
SCLC-A
F
chr11: 60681552-
S_Shelf







60682268


cg11634198
chr17: 37764158
NEUROD2.UTR5
SCLC-A
F
chr17: 37764092-
Island







37764304


cg15798221
chr17: 62773704
LOC146880.GENEBODY
SCLC-A
R
chr17: 62774366-
N_Shore







62777797


cg17930201
chr1: 155828174
SYT11.TSS1500
SCLC-A
R
chr1: 155829109-
N_Shore







155829431


cg19469357
chr7: 8474830
NXPH1.UTR5
SCLC-A
R
chr7: 8473139-8475199
Island


cg24112733
chr7: 38255578
STARD3NL.GENEBODY
SCLC-A
F


cg08897952
chr11: 126229062
ST3GAL4.UTR5
SCLC-A
R
chr11: 126225355-
S_Shelf







126226073


cg00144550
chr2: 100937796
LONRF2.GENEBODY
SCLC-A
R
chr2: 100937779-
Island







100939059


cg06286135
chr7: 157511479
PTPRN2.GENEBODY
SCLC-A
F


cg11303127
chr12: 49740807
DNAJC22.TSS1500
SCLC-A
F
chr12: 49738680-
Island







49740841


cg13969327
chr7: 127526253
SND1.GENEBODY
SCLC-A
F


cg18253971
chr18: 21900171
OSBPL1A.GENEBODY
SCLC-A
F


cg20104456
chr19: 51568523
KLK13.TSS200
SCLC-A
R
chr19: 51568154-
S_Shore







51568412


cg24247667
chr17: 74463439
AANAT.TSS200
SCLC-A
F


cg24901995
chr11: 888570
CHID1.GENEBODY
SCLC-A
R
chr11: 888684-888981
N_Shore


cg27320207
chr19: 15307057
NOTCH3.GENEBODY
SCLC-A
R
chr19: 15306243-
Island







15307111


cg03042971
chr17: 47301348
PHOSPHO1.UTR3
SCLC-A
R
chr17: 47301545-
N_Shore







47302477


cg03442858
chr1: 14924535
KIAA1026.TSS1500
SCLC-A
F
chr1: 14924610-
N_Shore







14925993


cg05020685
chr4: 40858965
APBB2.GENEBODY
SCLC-A
F
chr4: 40858884-
Island







40859162


cg07035875
chr16: 52557205
TOX3.UTR5
SCLC-A
R


cg07686441
chr15: 52570517
MIR1266.TSS1500
SCLC-A
R


cg12105190
chr6: 30653407
KIAA1949.GENEBODY
SCLC-A
R
chr6: 30654392-
N_Shore







30654934


cg18079653
chr10: 72648646
PCBD1.TSS200
SCLC-A
R
chr10: 72647738-
S_Shore







72648317


cg18090068
chr3: 55693316
C3orf51.GENEBODY
SCLC-A
R


cg14225450
chr6: 169637832
THBS2.GENEBODY
SCLC-A
F
chr6: 169641803-
N_Shelf







169642020


cg01200905
chr16: 52480264
TOX3.GENEBODY
SCLC-A
R


cg01119831
chr7: 2119608
MAD1L1.GENEBODY
SCLC-A
R
chr7: 2116367-2116781
S_Shelf


cg01593787
chr13: 111182949
RAB20.GENEBODY
SCLC-A
F


cg07543967
chr19: 49055443
SULT2B1.EXON1
SCLC-A
R


cg08389577
chr6: 3229379
TUBB2B.TSS1500
SCLC-A
R
chr6: 3227025-3229688
Island


cg13796218
chr1: 11750663
MAD2L2.UTR5
SCLC-A
R
chr1: 11750701-
N_Shore







11752651


cg14278148
chr9: 114663626
UGCG.GENEBODY
SCLC-A
F
chr9: 114658618-
S_Shelf







114659773


cg15927865
chr10: 104159579
NFKB2.GENEBODY
SCLC-A
F
chr10: 104159096-
S_Shore







104159536


cg16451995
chr16: 8942340
PMM2.UTR3
SCLC-A
R


cg17523945
chr19: 46732351
IGFL1.TSS1500
SCLC-A
F


cg17677988
chr4: 10687769
CLNK.TSS1500
SCLC-A
F


cg21323630
chr3: 51995784
PCBP4.UTR5
SCLC-A
R


cg23712594
chr1: 226591890
PARP1.GENEBODY
SCLC-N
R
chr1: 226595333-
N_Shelf







226595939


cg17170262
chr1: 184715203
EDEM3.GENEBODY
SCLC-N
F


cg05338397
chr1: 15466556
C1orf126.GENEBODY
SCLC-N
R


cg23682934
chr17: 42885322
GJC1.UTR5
SCLC-N
R


cg06195280
chr17: 6658706
XAF1.TSS1500
SCLC-N
F


cg01766396
chr2: 198436483
RFTN2.UTR3
SCLC-N
F


cg07990556
chr4: 159792176
FNIP2.GENEBODY
SCLC-N
F


cg24899626
chr8: 10512724
RP1L1.TSS200
SCLC-N
F


cg19028997
chr1: 205603040
ELK4.TSS1500
SCLC-N
R
chr1: 205600493-
S_Shore







205601432


cg12562403
chr12: 3214145
TSPAN9.UTR5
SCLC-N
R


cg08228249
chr22: 22062300
YPEL1.GENEBODY
SCLC-N
F
chr22: 22058079-
S_Shelf







22058304


cg27634115
chr2: 42423477
EML4.GENEBODY
SCLC-N
F


cg03861347
chr20: 46412713
SULF2.UTR5
SCLC-N
F
chr20: 46413742-
N_Shore







46415507


cg07941953
chr20: 10508668
C20orf94.GENEBODY
SCLC-N
R


cg03187411
chr7: 110482491
IMMP2L.GENEBODY
SCLC-N
R


cg03223734
chr20: 20180211
C20orf26.GENEBODY
SCLC-N
R


cg23793194
chr17: 37763735
NEUROD2.UTR5
SCLC-N
R
chr17: 37764092-
N_Shore







37764304


cg07831164
chr16: 10836225
NUBP1.TSS1500
SCLC-N
R
chr16: 10837584-
N_Shore







10838196


cg20674206
chr1: 63004738
DOCK7.GENEBODY
SCLC-N
F


cg22721827
chr16: 2520958
NTN3.TSS1500
SCLC-N
F
chr16: 2521086-2525929
N_Shore


cg27096416
chr7: 140599947
BRAF.GENEBODY
SCLC-N
F


cg03419151
chr17: 6658728
XAF1.TSS1500
SCLC-N
F


cg05420057
chr17: 36721297
SRCIN1.GENEBODY
SCLC-N
F
chr17: 36719544-
S_Shore







36719938


cg05950943
chr16: 2520971
NTN3.TSS1500
SCLC-N
F
chr16: 2521086-2525929
N_Shore


cg03243893
chr8: 2005683
MYOM2.GENEBODY
SCLC-N
R
chr8: 2003809-2004059
S_Shore


cg20255723
chr22: 45073031
PRR5.UTR5
SCLC-N
R


cg25275372
chr17: 964596
ABR.GENEBODY
SCLC-N
F


cg00284708
chr8: 43147581
POTEA.TSS200
SCLC-N
F


cg09305096
chr2: 189191655
GULP1.UTR5
SCLC-N
R


cg16696035
chr17: 17126176
FLCN.GENEBODY
SCLC-N
R
chr17: 17124698-
S_Shore







17124931


cg02966899
chr15: 64793532
ZNF609.GENEBODY
SCLC-N
R


cg09606564
chr17: 19290353
MFAP4.GENEBODY
SCLC-N
F


cg00332588
chr8: 43147564
POTEA.TSS200
SCLC-N
R


cg08041350
chr17: 25819112
KSR1.UTR5
SCLC-N
R


cg14074652
chr9: 136662289
VAV2.GENEBODY
SCLC-N
F
chr9: 136659111-
S_Shelf







136659329


cg19963589
chr1: 54822103
SSBP3.GENEBODY
SCLC-N
F
chr1: 54821990-
Island







54822333


cg09309024
chr16: 29837267
MVP.UTR5
SCLC-N
F


cg11952344
chr17: 80398854
HEXDC.GENEBODY
SCLC-N
F
chr17: 80397431-
S_Shore







80397642


cg20431135
chr17: 19290762
MFAP4.TSS1500
SCLC-N
F


cg19155699
chr3: 196050902
TM4SF19.GENEBODY
SCLC-N
F


cg23704362
chr8: 67405742
C8orf46.EXON1
SCLC-N
F


cg19991383
chr3: 55034387
CACNA2D3.GENEBODY
SCLC-N
F


cg00172603
chr1: 54822031
SSBP3.GENEBODY
SCLC-N
F
chr1: 54821990-
Island







54822333


cg06431681
chr2: 202330990
STRADB.GENEBODY
SCLC-N
F


cg14461974
chr2: 3318039
TSSC1.GENEBODY
SCLC-N
R
chr2: 3317676-3317935
S_Shore


cg15119221
chr17: 19290755
MFAP4.TSS1500
SCLC-N
F


cg21831649
chr1: 16050377
PLEKHM2.GENEBODY
SCLC-N
R
chr1: 16053616-
N_Shelf







16053975


cg06087554
chr16: 31151917
PRSS36.GENEBODY
SCLC-N
R
chr16: 31153556-
N_Shore







31154474


cg01293647
chr17: 37764264
NEUROD2.TSS200
SCLC-N
R
chr17: 37764092-
Island







37764304


cg14281144
chr9: 38421899
IGFBPL1.GENEBODY
SCLC-N
F
chr9: 38423947-
N_Shelf







38424584


cg13726218
chr13: 72438249
DACH1.GENEBODY
SCLC-N
R
chr13: 72439362-
N_Shore







72440059


cg17892159
chr2: 42274610
PKDCC.TSS1500
SCLC-N
F


cg10414350
chr8: 10210282
MSRA.GENEBODY
SCLC-N
R


cg20326410
chr1: 53600821
SLC1A7.GENEBODY
SCLC-N
R


cg06785060
chr1: 42180981
HIVEP3.UTR5
SCLC-N
F


cg07685557
chr16: 85685994
KIAA0182.GENEBODY
SCLC-N
F
chr16: 85684107-
S_Shore







85684491


cg08520443
chr17: 746641
NXN.GENEBODY
SCLC-N
R
chr17: 744617-744907
S_Shore


cg17322655
chr2: 242802127
PDCD1.TSS1500
SCLC-N
F
chr2: 242805752-
N_Shelf







242806034


cg00545232
chr13: 93923232
GPC6.GENEBODY
SCLC-N
R


cg11019127
chr11: 115369647
CADM1.GENEBODY
SCLC-N
F
chr11: 115373574-
N_Shelf







115375881


cg08151442
chr2: 238632428
LRRFIP1.GENEBODY
SCLC-N
F


cg16719771
chr8: 43147554
POTEA.TSS200
SCLC-N
R


cg20944379
chr1: 207069392
IL24.TSS1500
SCLC-N
R


cg03679521
chr17: 37764153
NEUROD2.UTR5
SCLC-N
F
chr17: 37764092-
Island







37764304


cg09440603
chr21: 43105616
NCRNA00111.GENEBODY
SCLC-N
F
chr21: 43109349-
N_Shelf







43109687


cg07360805
chr20: 36148457
BLCAP.UTR5
SCLC-N
F
chr20: 36148603-
N_Shore







36150136


cg01796800
chr17: 55595732
MSI2.GENEBODY
SCLC-N
F


cg06429887
chr14: 24600500
FITM1.TSS200
SCLC-N
F
chr14: 24601498-
N_Shore







24601700


cg10603757
chr22: 37621745
RAC2.UTR3
SCLC-N
R


cg13440795
chr8: 10210267
MSRA.GENEBODY
SCLC-N
R


cg03889044
chr2: 242802099
PDCD1.TSS1500
SCLC-N
F
chr2: 242805752-
N_Shelf







242806034


cg08200851
chr6: 5472095
FARS2.GENEBODY
SCLC-N
F


cg09414280
chr12: 120130253
CIT.GENEBODY
SCLC-N
R
chr12: 120127973-
S_Shore







120128291


cg21641186
chr3: 126200897
UROC1.UTR3
SCLC-N
R


cg21830368
chr17: 75373327
SEPT9.UTR5
SCLC-N
R
chr17: 75368688-
S_Shelf







75370506


cg04951371
chr2: 3317860
TSSC1.GENEBODY
SCLC-N
F
chr2: 3317676-3317935
Island


cg21557724
chr2: 3317928
TSSC1.GENEBODY
SCLC-N
R
chr2: 3317676-3317935
Island


cg12716832
chr22: 45073165
PRR5.UTR5
SCLC-N
R


cg04436083
chr4: 24567220
DHX15.GENEBODY
SCLC-N
R


cg11125249
chr3: 148737622
GYG1.GENEBODY
SCLC-N
F


cg11993925
chr19: 44307056
LYPD5.TSS1500
SCLC-N
F
chr19: 44302665-
S_Shelf







44303176


cg15293827
chr4: 2827194
SH3BP2.GENEBODY
SCLC-N
F


cg27531366
chr1: 27627058
WDTC1.GENEBODY
SCLC-N
F


cg01943029
chr16: 31715088
C16orf67.GENEBODY
SCLC-N
F
chr16: 31711839-
S_Shelf







31712343


cg13027937
chr7: 152525220
ACTR3B.GENEBODY
SCLC-N
F


cg16623710
chr22: 45073049
PRR5.UTR5
SCLC-N
F


cg00679520
chr12: 63133578
PPM1H.GENEBODY
SCLC-N
F


cg03742724
chr6: 161838997
PARK2.GENEBODY
SCLC-N
R


cg14300048
chr9: 72046240
APBA1.UTR3
SCLC-N
F


cg09720012
chr4: 108637177
PAPSS1.GENEBODY
SCLC-N
R
chr4: 108640845-
N_Shelf







108641835


cg22689630
chr19: 51568918
KLK13.TSS1500
SCLC-N
F
chr19: 51568154-
S_Shore







51568412


cg27068996
chr19: 51513883
KLK9.TSS1500
SCLC-N
F


cg09535960
chr8: 23193704
LOXL2.GENEBODY
SCLC-N
F


cg12575928
chr11: 22687660
GAS2.TSS1500
SCLC-N
R
chr11: 22688285-
N_Shore







22688617


cg02333237
chr14: 50802971
CDKL1.GENEBODY
SCLC-N
R


cg02734358
chr4: 90227074
GPRIN3.UTR5
SCLC-N
R
chr4: 90228714-
N_Shore







90229010


cg03118626
chr19: 51523252
KLK10.UTR5
SCLC-N
R
chr19: 51522004-
S_Shore







51522803


cg06358171
chr1: 54822008
SSBP3.GENEBODY
SCLC-N
R
chr1: 54821990-
Island







54822333


cg06440275
chr8: 2005701
MYOM2.GENEBODY
SCLC-N
R
chr8: 2003809-2004059
S_Shore


cg09393675
chr17: 37764250
NEUROD2.TSS200
SCLC-N
R
chr17: 37764092-
Island







37764304


cg20164964
chr12: 3213850
TSPAN9.UTR5
SCLC-N
R


cg02175739
chr11: 875980
CHID1.GENEBODY
SCLC-N
R


cg08969377
chr17: 80915263
B3GNTL1.GENEBODY
SCLC-N
R
chr17: 80918218-
N_Shelf







80919258


cg00317626
chr1: 53600741
SLC1A7.GENEBODY
SCLC-N
F


cg09382492
chr17: 74463681
AANAT.GENEBODY
SCLC-N
F


cg02516456
chr11: 1025091
MUC6.GENEBODY
SCLC-N
R
chr11: 1024746-1025359
Island


cg03737367
chr19: 50005045
MIR150.TSS1500
SCLC-N
R


cg13446863
chr9: 139259726
CARD9.GENEBODY
SCLC-N
R
chr9: 139257842-
S_Shore







139259075


cg02048220
chr14: 91141833
TTC7B.GENEBODY
SCLC-N
R


cg06760830
chr1: 47079672
MOBKL2C.GENEBODY
SCLC-N
F
chr1: 47078580-
S_Shore







47078967


cg11912239
chr17: 76220608
BIRC5.UTR3
SCLC-N
F


cg13525276
chr14: 81426012
TSHR.GENEBODY
SCLC-N
F


cg14025021
chr15: 43809510
MAP1A.TSS1500
SCLC-N
F


cg16960943
chr2: 236417185
AGAP1.GENEBODY
SCLC-N
R


cg17741629
chr13: 50024703
SETDB2.TSS1500
SCLC-N
R


cg04135110
chr5: 346695
AHRR.GENEBODY
SCLC-N
R
chr5: 343449-344535
S_Shelf


cg18722086
chr3: 113380072
KIAA2018.GENEBODY
SCLC-N
R


cg23141629
chr13: 45792582
GTF2F2.GENEBODY
SCLC-N
R


cg23571857
chr17: 6658898
XAF1.TSS1500
SCLC-N
F


cg05416911
chr12: 7176049
C1S.GENEBODY
SCLC-N
F


cg15341350
chr12: 119446891
SRRM4.GENEBODY
SCLC-N
F


cg15382095
chr17: 37762367
NEUROD2.GENEBODY
SCLC-N
F
chr17: 37761691-
Island







37763551


cg00795812
chr2: 242802009
PDCD1.TSS1500
SCLC-N
F
chr2: 242805752-
N_Shelf







242806034


cg14931683
chr17: 35872880
DUSP14.GENEBODY
SCLC-N
R
chr17: 35872722-
Island







35873026


cg05467716
chr17: 62774079
LOC146880.GENEBODY
SCLC-N
F
chr17: 62774366-
N_Shore







62777797


cg12097330
chr17: 79050221
BAIAP2.GENEBODY
SCLC-N
R
chr17: 79051892-
N_Shore







79052534


cg12517843
chr19: 17361126
USHBP1.GENEBODY
SCLC-N
F
chr19: 17356979-
S_Shelf







17357500


cg25216196
chr17: 19290520
MFAP4.TSS200
SCLC-N
R


cg27051683
chr2: 242802069
PDCD1.TSS1500
SCLC-N
F
chr2: 242805752-
N_Shelf







242806034


cg07290310
chr3: 125741734
SLC41A3.GENEBODY
SCLC-N
R


cg16360668
chr1: 19265059
IFFO2.GENEBODY
SCLC-N
R


cg12237784
chr7: 44187017
GCK.GENEBODY
SCLC-N
F
chr7: 44184770-
S_Shore







44185695


cg00175150
chr1: 150486261
ECM1.UTR3
SCLC-N
R
chr1: 150488036-
N_Shore







150488416


cg14292870
chr12: 6887543
LAG3.GENEBODY
SCLC-N
F


cg16007395
chr1: 33231070
KIAA1522.GENEBODY
SCLC-N
F


cg24980413
chr5: 346987
AHRR.GENEBODY
SCLC-N
R
chr5: 343449-344535
S_Shelf


cg10827768
chr2: 28387339
BRE.GENEBODY
SCLC-N
R


cg20340501
chr2: 233141525
DIS3L2.GENEBODY
SCLC-N
F


cg23271234
chr2: 71126275
VAX2.TSS1500
SCLC-N
F
chr2: 71126720-
N_Shore







71129209


cg03162164
chr7: 790384
HEATR2.GENEBODY
SCLC-N
F
chr7: 791984-792238
N_Shore


cg07727884
chr17: 19290503
MFAP4.TSS200
SCLC-N
R


cg27417749
chr15: 69449518
MIR548H4.GENEBODY
SCLC-N
R
chr15: 69452451-
N_Shelf







69453939


cg06603325
chr17: 39887725
HAP1.GENEBODY
SCLC-N
F
chr17: 39889956-
N_Shelf







39891489


cg03446876
chr7: 129414697
MIR96.TSS200
SCLC-N
R
chr7: 129418286-
N_Shelf







129422509


cg03454775
chr8: 2012595
MYOM2.GENEBODY
SCLC-N
R


cg09427374
chr2: 86095320
ST3GAL5.TSS1500
SCLC-N
R


cg10825315
chr14: 81425912
TSHR.GENEBODY
SCLC-N
R


cg17096191
chr1: 162039224
NOS1AP.TSS1500
SCLC-N
F
chr1: 162039450-
N_Shore







162040052


cg19784401
chr11: 46457992
AMBRA1.GENEBODY
SCLC-N
F


cg04876127
chr1: 33618450
TRIM62.GENEBODY
SCLC-N
R


cg11312087
chr13: 100944053
PCCA.GENEBODY
SCLC-N
R


cg14682005
chr6: 15337603
JARID2.GENEBODY
SCLC-N
R


cg16198315
chr13: 72438678
DACH1.GENEBODY
SCLC-N
R
chr13: 72439362-
N_Shore







72440059


cg20721467
chr10: 76597927
MYST4.UTR5
SCLC-N
F


cg23894058
chr19: 51537828
KLK12.GENEBODY
SCLC-N
F
chr19: 51535218-
S_Shelf







51535475


cg00892353
chr8: 124247948
C8orf76.GENEBODY
SCLC-N
R


cg08472243
chr16: 427912
TMEM8A.GENEBODY
SCLC-N
F
chr16: 426038-426290
S_Shore


cg10135894
chr4: 7862655
AFAP1.GENEBODY
SCLC-N
F


cg01146614
chr6: 159235211
EZR.GENEBODY
SCLC-N
F
chr6: 159239081-
N_Shelf







159240775


cg03470159
chr8: 10261798
MSRA.GENEBODY
SCLC-N
R
chr8: 10261900-
N_Shore







10262222


cg04629204
chr1: 26348325
EXTL1.EXON1
SCLC-N
F


cg15511928
chr1: 201895256
LMOD1.GENEBODY
SCLC-N
R


cg18482164
chr17: 37764118
NEUROD2.UTR5
SCLC-N
R
chr17: 37764092-
Island







37764304


cg23732608
chr20: 20180469
C20orf26.GENEBODY
SCLC-N
F


cg24355809
chr17: 746574
NXN.GENEBODY
SCLC-N
R
chr17: 744617-744907
S_Shore


cg19595760
chr1: 25948511
MAN1C1.GENEBODY
SCLC-N
F
chr1: 25944099-
S_Shelf







25944772


cg08853318
chr17: 71089186
SLC39A11.TSS1500
SCLC-N
F


cg21706038
chr2: 3317693
TSSC1.GENEBODY
SCLC-N
R
chr2: 3317676-3317935
Island


cg26577529
chr12: 52866845
KRT6C.GENEBODY
SCLC-N
R


cg01179256
chr12: 105141965
CHST11.GENEBODY
SCLC-N
F


cg02069944
chr17: 79191523
AZI1.GENEBODY
SCLC-N
R


cg13409077
chr9: 35618528
CD72.TSS200
SCLC-N
R
chr9: 35616980-
S_Shore







35617324


cg13700197
chr9: 98221975
PTCH1.GENEBODY
SCLC-N
R


cg13867915
chr1: 27050039
ARID1A.GENEBODY
SCLC-N
F


cg24083274
chr7: 121977191
CADPS2.GENEBODY
SCLC-N
F


cg05337753
chr17: 75373407
SEPT9.UTR5
SCLC-N
F
chr17: 75368688-
S_Shelf







75370506


cg07533819
chr5: 71407465
MAP1B.GENEBODY
SCLC-N
F
chr5: 71402877-
S_Shelf







71404868


cg17327404
chr1: 33231109
KIAA1522.GENEBODY
SCLC-N
R


cg02627403
chr17: 73823769
UNC13D.UTR3
SCLC-N
R


cg11552585
chr19: 3196206
NCLN.GENEBODY
SCLC-N
F
chr19: 3196188-3196393
Island


cg13406860
chr9: 132881336
GPR107.GENEBODY
SCLC-N
F


cg17492795
chr1: 214637903
PTPN14.GENEBODY
SCLC-N
R


cg18590709
chr17: 49122713
SPAG9.GENEBODY
SCLC-N
R


cg24054871
chr22: 45073148
PRR5.UTR5
SCLC-N
R


cg13404038
chr9: 126123344
CRB2.GENEBODY
SCLC-N
F


cg16797751
chr7: 105290218
ATXN7L1.GENEBODY
SCLC-N
F


cg04607412
chr22: 45073157
PRR5.UTR5
SCLC-N
R


cg11213150
chr9: 129884457
ANGPTL2.UTR5
SCLC-N
F


cg19921389
chr3: 128780164
GP9.UTR5
SCLC-N
R


cg10784542
chr6: 169625369
THBS2.GENEBODY
SCLC-N
R
chr6: 169622297-
S_Shelf







169622520


cg21303745
chr17: 77959826
TBC1D16.GENEBODY
SCLC-N
F


cg06786238
chr1: 33231190
KIAA1522.GENEBODY
SCLC-N
R


cg09021393
chr7: 95849568
MIR591.TSS1500
SCLC-N
R


cg14121282
chr9: 137268074
RXRA.GENEBODY
SCLC-N
F


cg17697739
chr6: 1873340
GMDS.GENEBODY
SCLC-N
R


cg21885317
chr8: 124248094
C8orf76.GENEBODY
SCLC-N
F


cg01429256
chr17: 17687834
RAI1.UTR5
SCLC-N
F
chr17: 17685016-
S_Shore







17687240


cg02582754
chr6: 160327345
MAS1.TSS1500
SCLC-N
R


cg07997493
chr17: 37761947
NEUROD2.GENEBODY
SCLC-N
R
chr17: 37761691-
Island







37763551


cg21565781
chr12: 123892621
SETD8.UTR3
SCLC-N
R


cg02381521
chr21: 42775934
MX2.GENEBODY
SCLC-N
F


cg09768257
chr8: 11628346
NEIL2.UTR5
SCLC-N
R
chr8: 11627091-
S_Shore







11627668


cg12205591
chr21: 44588552
CRYAA.TSS1500
SCLC-N
F
chr21: 44590612-
N_Shelf







44590826


cg18875674
chr11: 73026651
ARHGEF17.GENEBODY
SCLC-N
F


cg08958913
chr19: 40193890
LGALS14.TSS1500
SCLC-N
R


cg20712415
chr3: 159570903
SCHIP1.GENEBODY
SCLC-N
F


cg24653772
chr7: 788989
HEATR2.GENEBODY
SCLC-N
F
chr7: 791984-792238
N_Shelf


cg10529401
chr1: 53587046
SLC1A7.GENEBODY
SCLC-N
F


cg13909661
chr12: 26386833
SSPN.UTR3
SCLC-N
R


cg14388093
chr9: 133342842
ASS1.GENEBODY
SCLC-N
F


cg27554156
chr12: 13248725
GSG1.GENEBODY
SCLC-N
F


cg00452755
chr1: 28864993
SNHG3-
SCLC-N
R




RCC1.GENEBODY


cg02807008
chr19: 1910258
ADAT3.UTR5
SCLC-N
R
chr19: 1911923-1913406
N_Shore


cg14448919
chr5: 435040
AHRR.UTR3
SCLC-N
F


cg17873750
chr1: 116382984
NHLH2.UTR5
SCLC-N
F
chr1: 116380359-
S_Shore







116382364


cg26844077
chr16: 85658855
KIAA0182.UTR5
SCLC-N
F
chr16: 85658742-
Island







85658998


cg26902557
chr11: 1585852
DUSP8.GENEBODY
SCLC-N
F


cg06479434
chr7: 128395929
CALU.GENEBODY
SCLC-N
R


cg08811581
chr11: 16902852
PLEKHA7.GENEBODY
SCLC-N
F


cg08902205
chr16: 85658997
KIAA0182.UTR5
SCLC-N
F
chr16: 85658742-
Island







85658998


cg18023842
chr1: 160336475
NHLH1.TSS1500
SCLC-N
F


cg21448423
chr1: 55013956
ACOT11.EXON1
SCLC-N
R


cg07923746
chr1: 179050803
TOR3A.TSS1500
SCLC-N
F
chr1: 179051075-
N_Shore







179051948


cg10987071
chr2: 217276744
SMARCAL1.TSS1500
SCLC-N
F
chr2: 217277037-
N_Shore







217277557


cg14423168
chr8: 41400312
GINS4.UTR3
SCLC-N
R


cg07397891
chr1: 246582071
SMYD3.GENEBODY
SCLC-N
F


cg09997760
chr3: 179169556
GNB4.TSS200
SCLC-N
R
chr3: 179168735-
Island







179169593


cg18405786
chr19: 18746985
KLHL26.TSS1500
SCLC-N
F


cg24852561
chr13: 100340080
CLYBL.GENEBODY
SCLC-N
F


cg04702527
chr4: 139940407
CCRN4L.GENEBODY
SCLC-N
F
chr4: 139936443-
S_Shelf







139937428


cg23994112
chr17: 75373457
SEPT9.UTR5
SCLC-N
R
chr17: 75368688-
S_Shelf







75370506


cg05428433
chr16: 3614067
NLRC3.GENEBODY
SCLC-N
F
chr16: 3614316-3614601
N_Shore


cg09138688
chr5: 49963801
PARP8.GENEBODY
SCLC-N
F
chr5: 49962267-
S_Shore







49963777


cg11367404
chr4: 170180146
SH3RF1.GENEBODY
SCLC-N
R


cg15179499
chr5: 362529
AHRR.GENEBODY
SCLC-N
R
chr5: 356570-359526
S_Shelf


cg20782117
chr7: 95865631
SLC25A13.GENEBODY
SCLC-N
R


cg23296791
chr19: 40229766
CLC.TSS1500
SCLC-N
F


cg24524634
chr7: 2800976
GNA12.GENEBODY
SCLC-N
F
chr7: 2802440-2802698
N_Shore


cg09309711
chr19: 17322661
MYO9B.UTR3
SCLC-N
F
chr19: 17322471-
Island







17322988


cg18254848
chr19: 40227949
CLC.GENEBODY
SCLC-N
F


cg08157318
chr12: 102224140
GNPTAB.GENEBODY
SCLC-N
R
chr12: 102224262-
N_Shore







102224614


cg10833439
chr21: 42793818
MX1.UTR5
SCLC-N
F
chr21: 42792293-
S_Shore







42792704


cg12102573
chr17: 27924969
ANKRD13B.GENEBODY
SCLC-N
F
chr17: 27919874-
S_Shelf







27921105


cg00756860
chr1: 144852047
PDE4DIP.UTR3
SCLC-N
R


cg01120953
chr5: 149643466
CAMK2A.GENEBODY
SCLC-N
R


cg09980085
chr19: 40174352
LOC400696.UTR3
SCLC-N
F


cg13913247
chr4: 141207827
SCOC.UTR5
SCLC-N
F


cg17568996
chr22: 42828125
NFAM1.GENEBODY
SCLC-N
F


cg04571652
chr3: 192959762
MGC2889.GENEBODY
SCLC-N
F
chr3: 192958709-
S_Shore







192959373


cg06256596
chr16: 66511944
BEAN.GENEBODY
SCLC-N
R


cg06772157
chr7: 100728711
TRIM56.TSS200
SCLC-N
F
chr7: 100732088-
N_Shelf







100732424


cg25368586
chr13: 111561018
ANKRD10.GENEBODY
SCLC-N
F


cg23202177
chr1: 116383238
NHLH2.UTR5
SCLC-N
R
chr1: 116380359-
S_Shore







116382364


cg16419345
chr17: 73976089
ACOX1.TSS1500
SCLC-N
R
chr17: 73974971-
S_Shore







73975731


cg22807608
chr17: 17594719
RAI1.UTR5
SCLC-N
F
chr17: 17597824-
N_Shelf







17598398


cg26772172
chr17: 77474395
HRNBP3.UTR5
SCLC-N
R


cg02566157
chr11: 61025815
VWCE.UTR3
SCLC-N
R


cg02851203
chr1: 54808689
SSBP3.GENEBODY
SCLC-N
F


cg08247612
chr1: 160336486
NHLH1.TSS1500
SCLC-N
F


cg20367923
chr6: 169624501
THBS2.GENEBODY
SCLC-N
R
chr6: 169622297-
S_Shore







169622520


cg22460466
chr7: 1896154
MAD1L1.GENEBODY
SCLC-N
F
chr7: 1896090-1896451
Island


cg04530460
chr6: 42858550
C6orf226.UTR5
SCLC-N
F
chr6: 42858169-
Island







42858960


cg07424295
chr10: 92980030
PCGF5.TSS1500
SCLC-N
R
chr10: 92980347-
N_Shore







92980832


cg09135866
chr19: 53238498
ZNF611.TSS200
SCLC-N
F
chr19: 53237861-
Island







53238499


cg22102078
chr6: 130182512
C6orf191.TSS200
SCLC-N
R


cg04155280
chr17: 26692719
SEBOX.GENEBODY
SCLC-N
F


cg08976117
chr3: 57064983
ARHGEF3.GENEBODY
SCLC-N
R


cg02997295
chr6: 169642301
THBS2.GENEBODY
SCLC-N
F
chr6: 169641803-
S_Shore







169642020


cg08399444
chr12: 13248548
GSG1.GENEBODY
SCLC-N
F


cg27379887
chr20: 1448498
NSFL1C.TSS200
SCLC-N
R
chr20: 1446936-1447729
S_Shore


cg21831485
chr7: 31594014
CCDC129.GENEBODY
SCLC-N
F


cg20292636
chr1: 204328377
PLEKHA6.UTR5
SCLC-N
F


cg23316807
chr19: 56628171
ZNF787.UTR5
SCLC-N
F
chr19: 56631771-
N_Shelf







56633076


cg03361664
chr11: 3187760
OSBPL5.TSS1500
SCLC-N
R
chr11: 3186131-3186768
S_Shore


cg11759917
chr17: 79655302
HGS.GENEBODY
SCLC-N
R
chr17: 79655162-
Island







79655515


cg17861836
chr17: 79202505
C17orf56.UTR3
SCLC-N
F


cg19046189
chr19: 49316732
HSD17B14.GENEBODY
SCLC-N
F
chr19: 49315545-
S_Shore







49315765


cg25342005
chr1: 33648656
TRIM62.TSS1500
SCLC-N
R
chr1: 33646613-
S_Shore







33647878


cg08301181
chr17: 73780373
UNK.TSS1500
SCLC-N
R
chr17: 73780846-
N_Shore







73781308


cg23490611
chrX: 134475099
ZNF75D.UTR5
SCLC-N
R
chrX: 134477583-
N_Shelf







134477999


cg27569829
chr18: 60984485
BCL2.GENEBODY
SCLC-N
R
chr18: 60985503-
N_Shore







60985741


cg01157146
chr21: 42877638
TMPRSS2.GENEBODY
SCLC-N
R
chr21: 42878751-
N_Shore







42880674


cg03155027
chr3: 49907692
CAMKV.TSS1500
SCLC-N
F
chr3: 49906737-
S_Shore







49907482


cg14269510
chr13: 47204488
LRCH1.GENEBODY
SCLC-N
R


cg18849256
chr12: 32309670
BICD1.GENEBODY
SCLC-N
F


cg21930140
chr21: 42796537
MX1.TSS1500
SCLC-N
F
chr21: 42798146-
N_Shore







42798884


cg22377043
chr15: 43809486
MAP1A.TSS1500
SCLC-N
F


cg00928231
chr11: 67195771
RPS6KB2.TSS200
SCLC-N
F
chr11: 67195800-
N_Shore







67196190


cg04329478
chr19: 40169839
LOC400696.TSS200
SCLC-N
F


cg05070839
chr8: 10261641
MSRA.GENEBODY
SCLC-N
F
chr8: 10261900-
N_Shore







10262222


cg16145834
chr6: 33282321
TAPBP.TSS200
SCLC-N
R
chr6: 33282855-
N_Shore







33283196


cg01654446
chr6: 33280476
TAPBP.GENEBODY
SCLC-N
R
chr6: 33281112-
N_Shore







33281827


cg15396570
chr1: 85931161
DDAH1.TSS1500
SCLC-N
F
chr1: 85929940-
Island







85931168


cg17637107
chr8: 20054583
ATP6V1B2.TSS200
SCLC-N
R
chr8: 20054546-
Island







20055027


cg14373410
chr14: 81426234
TSHR.GENEBODY
SCLC-N
R


cg22692213
chr12: 133533186
ZNF605.TSS1500
SCLC-N
F
chr12: 133532642-
S_Shore







133532979


cg01033600
chr19: 7964703
LRRC8E.GENEBODY
SCLC-N
F
chr19: 7964439-7964704
Island


cg15472885
chr3: 71056608
FOXP1.GENEBODY
SCLC-N
R


cg23596678
chr17: 79793000
DYSFIP1.TSS200
SCLC-N
R
chr17: 79790530-
S_Shore







79791553


cg16616765
chr2: 197456534
HECW2.UTR5
SCLC-N
R
chr2: 197457392-
N_Shore







197458522


cg21221712
chr15: 86132153
AKAP13.GENEBODY
SCLC-N
F


cg26130023
chr18: 45453609
SMAD2.UTR5
SCLC-N
R
chr18: 45456484-
N_Shelf







45458024


cg26539941
chr2: 220306470
SPEG.GENEBODY
SCLC-N
R
chr2: 220306855-
N_Shore







220307096


cg14962159
chr13: 37441585
SMAD9.GENEBODY
SCLC-N
F


cg03466032
chr17: 39968802
FKBP10.TSS200
SCLC-N
R
chr17: 39967407-
S_Shore







39968604


cg22862003
chr21: 42797588
MX1.TSS1500
SCLC-N
F
chr21: 42798146-
N_Shore







42798884


cg05801879
chr16: 84101832
MBTPS1.GENEBODY
SCLC-N
F


cg08093568
chr7: 27626595
HIBADH.GENEBODY
SCLC-N
F


cg14398557
chr20: 1095840
PSMF1.UTR5
SCLC-N
R
chr20: 1099078-1099561
N_Shelf


cg05152503
chr20: 30407098
MYLK2.TSS200
SCLC-N
R
chr20: 30410547-
N_Shelf







30410832


cg15040499
chr17: 35861263
DUSP14.UTR5
SCLC-N
R


cg04420932
chr11: 67195621
RPS6KB2.TSS1500
SCLC-N
F
chr11: 67195800-
N_Shore







67196190


cg22970357
chr2: 119600408
EN1.UTR3
SCLC-N
R
chr2: 119599458-
Island







119600966


cg10288437
chr6: 158432894
SYNJ2.GENEBODY
SCLC-N
F


cg20976787
chr6: 43064460
PTK7.GENEBODY
SCLC-N
R


cg10294732
chr4: 41614397
LIMCH1.GENEBODY
SCLC-N
F


cg19314992
chr11: 76614479
ACER3.GENEBODY
SCLC-N
R


cg00791283
chr12: 79498966
SYT1.UTR5
SCLC-N
R


cg16125375
chr5: 146298512
PPP2R2B.UTR5
SCLC-N
R


cg13663667
chr19: 4180236
SIRT6.GENEBODY
SCLC-N
F
chr19: 4182259-4182803
N_Shelf


cg02711899
chr6: 42410890
TRERF1.UTR5
SCLC-N
R


cg26181372
chr9: 104198262
ALDOB.TSS1500
SCLC-N
R


cg22780475
chr19: 45281526
CBLC.EXON1
SCLC-N
F
chr19: 45281133-
S_Shore







45281355


cg13127741
chr20: 31331821
COMMD7.TSS200
SCLC-N
F
chr20: 31330957-
S_Shore







31331410


cg08352439
chr7: 55637123
VOPP1.GENEBODY
SCLC-N
F
chr7: 55639277-
N_Shelf







55640599


cg04528038
chr16: 21171097
TMEM159.UTR5
SCLC-N
F
chr16: 21169810-
S_Shore







21170278


cg09336589
chr17: 7107939
DLG4.GENEBODY
SCLC-N
F
chr17: 7108304-7108654
N_Shore


cg25976170
chr22: 29707585
GAS2L1.UTR3
SCLC-N
F
chr22: 29707479-
Island







29707797


cg07557423
chr4: 42657903
ATP8A1.GENEBODY
SCLC-N
F
chr4: 42658278-
N_Shore







42659550


cg06342490
chr2: 42795193
MTA3.TSS1500
SCLC-N
F
chr2: 42795847-
N_Shore







42796230


cg21574244
chr15: 42568411
GANC.GENEBODY
SCLC-N
F
chr15: 42565452-
S_Shelf







42565791


cg00551589
chr16: 2626391
PDPK1.GENEBODY
SCLC-N
R
chr16: 2627134-2627399
N_Shore


cg07127888
chr8: 41400789
GINS4.UTR3
SCLC-N
F


cg16293838
chr1: 6330521
ACOT7.GENEBODY
SCLC-N
F


cg17461336
chr7: 99441559
CYP3A43.GENEBODY
SCLC-N
R


cg26207423
chr8: 28787952
HMBOX1.UTR5
SCLC-N
R


cg01489441
chr16: 1764111
MAPK8IP3.GENEBODY
SCLC-N
R


cg17397069
chr5: 156110742
SGCD.GENEBODY
SCLC-N
R


cg27434467
chr10: 101686326
NCRNA00093.TSS1500
SCLC-N
F


cg15580167
chr2: 175629219
CHRNA1.TSS200
SCLC-N
F


cg26245086
chr4: 87860957
AFF1.UTR5
SCLC-N
F
chr4: 87855873-
S_Shelf







87857204


cg07696516
chr4: 41614958
LIMCH1.EXON1
SCLC-N
F


cg16457351
chr5: 176297315
UNC5A.GENEBODY
SCLC-N
R
chr5: 176296541-
S_Shore







176296933


cg01372366
chr11: 48041783
PTPRJ.GENEBODY
SCLC-N
F


cg14414874
chr9: 126157693
DENND1A.GENEBODY
SCLC-N
F
chr9: 126154226-
S_Shelf







126154562


cg16039867
chr1: 47023134
MKNK1.GENEBODY
SCLC-N
R


cg23615892
chr1: 215825505
USH2A.GENEBODY
SCLC-N
R


cg13763232
chr3: 14443428
SLC6A6.TSS1500
SCLC-N
R
chr3: 14443629-
N_Shore







14444577


cg00957901
chr4: 41614842
LIMCH1.TSS200
SCLC-N
R


cg01794926
chr15: 92470387
SLCO3A1.GENEBODY
SCLC-N
R


cg03167954
chr22: 29707782
GAS2L1.UTR3
SCLC-N
R
chr22: 29707479-
Island







29707797


cg22976732
chr22: 28191914
MN1.GENEBODY
SCLC-N
F
chr22: 28192793-
N_Shore







28198592


cg00927494
chr11: 69924230
ANO1.TSS200
SCLC-N
R
chr11: 69924338-
N_Shore







69925197


cg21661983
chr12: 72353490
TPH2.GENEBODY
SCLC-N
F


cg00664609
chr16: 2198075
RAB26.TSS1500
SCLC-N
R
chr16: 2198455-2199129
N_Shore


cg16544220
chr6: 33095030
HLA-DPB2.GENEBODY
SCLC-N
F


cg00718444
chr8: 145685564
CYHR1.GENEBODY
SCLC-N
F
chr8: 145687389-
N_Shore







145687880


cg03227338
chr11: 46998965
C11orf49.GENEBODY
SCLC-N
F


cg13491737
chr13: 111295728
CARS2.GENEBODY
SCLC-N
R
chr13: 111294675-
S_Shore







111294900


cg23924526
chr2: 45998548
PRKCE.GENEBODY
SCLC-N
R


cg03180426
chr9: 139964156
C9orf140.GENEBODY
SCLC-N
R
chr9: 139964155-
Island







139965284


cg21579399
chr2: 11890700
LPIN1.UTR5
SCLC-N
F
chr2: 11886249-
S_Shelf







11887207


cg00249974
chr1: 156254149
TMEM79.EXON1
SCLC-N
R


cg15585294
chr11: 22687641
GAS2.TSS1500
SCLC-N
R
chr11: 22688285-
N_Shore







22688617


cg10153942
chr19: 54982500
CDC42EP5.UTR5
SCLC-N
R
chr19: 54982388-
Island







54982897


cg11282156
chr3: 63428840
SYNPR.UTR5
SCLC-N
F


cg18003659
chr2: 175629267
CHRNA1.TSS200
SCLC-N
R


cg22340762
chr1: 183823538
RGL1.GENEBODY
SCLC-N
F


cg00408605
chr8: 141466079
TRAPPC9.UTR5
SCLC-P
R
chr8: 141467218-
N_Shore







141467927


cg00600617
chr6: 107221887
LOC553137.GENEBODY
SCLC-P
F


cg00618183
chr17: 75143600
SEC14L1.GENEBODY
SCLC-P
R


cg00625110
chr16: 53741731
FTO.GENEBODY
SCLC-P
R
chr16: 53737617-
S_Shelf







53738235


cg00703885
chr2: 128440247
LIMS2.TSS1500
SCLC-P
F


cg00704369
chr7: 81996559
CACNA2D1.GENEBODY
SCLC-P
R


cg00706536
chr17: 40609826
ATP6VOA1.TSS1500
SCLC-P
R
chr17: 40610746-
N_Shore







40611032


cg01149239
chr3: 196746085
MFI2.UTR3
SCLC-P
F


cg01307483
chr7: 129254604
NRF1.UTR5
SCLC-P
F
chr7: 129251237-
S_Shelf







129252441


cg01580044
chr1: 114300656
PHTF1.GENEBODY
SCLC-P
R
chr1: 114301514-
N_Shore







114302272


cg01626895
chr12: 116425790
MED13L.GENEBODY
SCLC-P
R


cg01653080
chr14: 104205041
PPP1R13B.GENEBODY
SCLC-P
F
chr14: 104205070-
N_Shore







104205329


cg01715088
chr1: 6520772
ESPN.UTR3
SCLC-P
R
chr1: 6520584-6521955
Island


cg02220284
chr3: 71013485
FOXP1.GENEBODY
SCLC-P
F


cg02253499
chr3: 12602046
MKRN2.GENEBODY
SCLC-P
F
chr3: 12598391-
S_Shelf







12599051


cg02330721
chr16: 1764231
MAPK8IP3.GENEBODY
SCLC-P
R


cg02519218
chr12: 133424286
CHFR.GENEBODY
SCLC-P
R


cg02793948
chr11: 68095662
LRP5.GENEBODY
SCLC-P
F


cg03075214
chr11: 64867914
C11orf2.GENEBODY
SCLC-P
R
chr11: 64863698-
S_Shelf







64863980


cg03147598
chr2: 131104160
IMP4.UTR3
SCLC-P
F
chr2: 131099469-
S_Shelf







131100863


cg03264729
chr11: 72347339
PDE2A.GENEBODY
SCLC-P
R


cg03803789
chr11: 111854003
DIXDC1.GENEBODY
SCLC-P
R


cg04390667
chr11: 46624867
HARBI1.UTR3
SCLC-P
R


cg05001389
chr9: 135853034
GFI1B.TSS1500
SCLC-P
R


cg05661060
chr1: 44074454
PTPRF.GENEBODY
SCLC-P
F
chr1: 44070892-
S_Shelf







44071142


cg06206957
chr7: 33080615
NT5C3.TSS200
SCLC-P
R


cg06604199
chr20: 31331973
COMMD7.TSS200
SCLC-P
R
chr20: 31330957-
S_Shore







31331410


cg06669752
chr5: 138534431
SIL1.TSS1500
SCLC-P
R
chr5: 138533870-
S_Shore







138534113


cg06832246
chr11: 93224210
C11orf75.UTR5
SCLC-P
R


cg06839854
chr2: 10536115
HPCAL1.UTR5
SCLC-P
R


cg07205154
chr1: 176147105
RFWD2.GENEBODY
SCLC-P
R


cg07313835
chr1: 167342724
POU2F1.GENEBODY
SCLC-P
F


cg07699978
chr12: 63194001
PPM1H.GENEBODY
SCLC-P
R
chr12: 63195657-
N_Shore







63195909


cg07859138
chrX: 118751995
SEPT6.UTR3
SCLC-P
F


cg07956003
chr7: 95433460
DYNC111.UTR5
SCLC-P
F


cg08101329
chr17: 4884631
CAMTA2.GENEBODY
SCLC-P
R


cg08238265
chr14: 64682912
SYNE2.EXON1
SCLC-P
R


cg08781755
chr2: 44172074
LRPPRC.GENEBODY
SCLC-P
F


cg09169413
chr12: 48103670
P11.UTR3
SCLC-P
F
chr12: 48099317-
S_Shelf







48099905


cg10386431
chr1: 77879031
AK5.GENEBODY
SCLC-P
F


cg10887937
chr12: 112203795
ALDH2.TSS1500
SCLC-P
R
chr12: 112204498-
N_Shore







112204979


cg11019743
chr6: 168267395
MLLT4.GENEBODY
SCLC-P
F


cg11132582
chr1: 167217689
POU2F1.UTR5
SCLC-P
F


cg11447040
chr20: 37667339
DHX35.UTR3
SCLC-P
R


cg11701604
chr11: 36095771
LDLRAD3.GENEBODY
SCLC-P
F


cg13146674
chr11: 68095623
LRP5.GENEBODY
SCLC-P
R


cg13556548
chr1: 226187876
C1orf55.TSS1500
SCLC-P
R
chr1: 226186803-
S_Shore







226187336


cg13578134
chr15: 75081572
CSK.UTR5
SCLC-P
R


cg13619387
chr9: 92050313
SEMA4D.UTR5
SCLC-P
R


cg13676816
chr9: 91976972
SEMA4D.UTR3
SCLC-P
R


cg14211075
chr9: 135818481
TSC1.UTR5
SCLC-P
R
chr9: 135819526-
N_Shore







135820529


cg14301030
chr10: 264920
ZMYND11.GENEBODY
SCLC-P
R


cg14302130
chr6: 33032830
HLA-DPA1.UTR3
SCLC-P
R


cg14457284
chr9: 135852984
GFI1B.TSS1500
SCLC-P
R


cg14701925
chr3: 128980811
COPG.GENEBODY
SCLC-P
F


cg14817765
chr20: 2444494
SNORD119.TSS1500
SCLC-P
F


cg15337905
chr7: 150807508
AGAP3.GENEBODY
SCLC-P
R


cg15425670
chr2: 42461109
EML4.GENEBODY
SCLC-P
F


cg15724534
chr2: 211018363
C2orf67.GENEBODY
SCLC-P
R


cg15873449
chr18: 12885569
PTPN2.TSS1500
SCLC-P
F
chr18: 12883285-
S_Shore







12884578


cg16318349
chr1: 154917307
PBXIP1.UTR3
SCLC-P
R


cg16691863
chr1: 28848173
SNHG3-
SCLC-P
R
chr1: 28844653-
S_Shelf




RCC1.GENEBODY


28845293


cg17308493
chr10: 30634469
MTPAP.GENEBODY
SCLC-P
F
chr10: 30637961-
N_Shelf







30638279


cg17355865
chr11: 76887139
MYO7A.GENEBODY
SCLC-P
R
chr11: 76890783-
N_Shelf







76890986


cg17758792
chr21: 37620038
DOPEY2.GENEBODY
SCLC-P
F
chr21: 37617467-
S_Shelf







37617872


cg18455249
chr4: 56813898
CEP135.TSS1500
SCLC-P
R
chr4: 56814800-
N_Shore







56815511


cg18872426
chr19: 38874037
PSMD8.UTR3
SCLC-P
F
chr19: 38876070-
N_Shelf







38876332


cg19125791
chr2: 240265915
HDAC4.GENEBODY
SCLC-P
F


cg19506380
chr8: 98740612
MTDH.UTR3
SCLC-P
F


cg19918623
chr7: 132661002
CHCHD3.GENEBODY
SCLC-P
R


cg20059682
chr12: 52201821
SCN8A.UTR3
SCLC-P
F


cg20467658
chr15: 89933347
LOC254559.GENEBODY
SCLC-P
R


cg20497631
chr8: 8647440
MFHAS1.GENEBODY
SCLC-P
R


cg20664313
chr12: 133071297
FBRSL1.GENEBODY
SCLC-P
R
chr12: 133073397-
N_Shelf







133073632


cg20716489
chr3: 195591877
TNK2.GENEBODY
SCLC-P
R
chr3: 195594836-
N_Shelf







195595494


cg21232015
chr12: 133424221
CHFR.GENEBODY
SCLC-P
R


cg21289124
chr22: 26951249
TPST2.UTR5
SCLC-P
R


cg21535670
chr8: 140798600
TRAPPC9.GENEBODY
SCLC-P
F


cg21877565
chr1: 156461550
MEF2D.UTR5
SCLC-P
F


cg21927971
chr2: 17837235
VSNL1.UTR3
SCLC-P
R


cg21940081
chr2: 131103235
IMP4.GENEBODY
SCLC-P
R
chr2: 131099469-
S_Shelf







131100863


cg22542731
chr2: 128440274
LIMS2.TSS1500
SCLC-P
F


cg23396732
chr20: 31332170
COMMD7.TSS1500
SCLC-P
F
chr20: 31330957-
S_Shore







31331410


cg24136932
chr8: 22281979
SLC39A14.GENEBODY
SCLC-P
R


cg24440131
chr1: 26880207
MIR1976.TSS1500
SCLC-P
R


cg24495350
chr15: 72651198
HEXA.GENEBODY
SCLC-P
F


cg24677222
chr3: 140102647
CLSTN2.GENEBODY
SCLC-P
F


cg25601286
chr2: 169408033
LASS6.GENEBODY
SCLC-P
R


cg25874150
chr10: 34941561
PARD3.GENEBODY
SCLC-P
R


cg26224018
chr1: 64942153
CACHD1.GENEBODY
SCLC-P
F


cg26542660
chr4: 56813860
CEP135.TSS1500
SCLC-P
R
chr4: 56814800-
N_Shore







56815511


cg26579713
chr15: 65701865
IGDCC4.GENEBODY
SCLC-P
F


cg26797073
chr2: 131129811
PTPN18.GENEBODY
SCLC-P
F
chr2: 131129718-
Island







131130511


cg27053763
chr5: 180653815
TRIM41.GENEBODY
SCLC-P
R
chr5: 180650099-
S_Shelf







180650679


cg27222157
chr11: 66382978
RBM14.TSS1500
SCLC-P
F
chr11: 66383571-
N_Shore







66385047


cg27254046
chr6: 57272398
PRIM2.GENEBODY
SCLC-P
F


cg00854324
chr16: 69941269
WWP2.GENEBODY
SCLC-P
R


cg01099470
chr2: 131103656
IMP4.GENEBODY
SCLC-P
F
chr2: 131099469-
S_Shelf







131100863


cg02428072
chr3: 169900473
PHC3.TSS1500
SCLC-P
F
chr3: 169898946-
S_Shore







169899626


cg03152913
chr2: 178975712
RBM45.TSS1500
SCLC-P
R
chr2: 178977078-
N_Shore







178977828


cg03356778
chr11: 120110544
POU2F3.TSS1500
SCLC-P
F
chr11: 120110497-
Island







120110719


cg04976330
chr1: 31480640
PUM1.GENEBODY
SCLC-P
R


cg05399330
chr1: 55464530
BSND.TSS200
SCLC-P
R
chr1: 55462688-
S_Shore







55463010


cg06912922
chr19: 12708229
ZNF490.GENEBODY
SCLC-P
F
chr19: 12707696-
S_Shore







12708114


cg07993367
chr7: 149568778
ATP6VOE2.TSS1500
SCLC-P
R
chr7: 149570366-
N_Shore







149571272


cg08313040
chr6: 33092243
HLA-DPB2.GENEBODY
SCLC-P
F


cg08320861
chr6: 33095982
HLA-DPB2.GENEBODY
SCLC-P
R


cg08651894
chr1: 154832235
KCNN3.GENEBODY
SCLC-P
R


cg09417011
chr1: 54842404
SSBP3.GENEBODY
SCLC-P
F


cg09735908
chr16: 88770558
RNF166.GENEBODY
SCLC-P
F
chr16: 88772237-
N_Shore







88773195


cg10833114
chr12: 72246108
MRS2P2.TSS1500
SCLC-P
F


cg12022772
chr2: 131130468
PTPN18.GENEBODY
SCLC-P
R
chr2: 131129718-
Island







131130511


cg12598235
chr15: 89921182
LOC254559.TSS200
SCLC-P
R
chr15: 89920793-
Island







89922768


cg15109449
chr1: 12363259
VPS13D.GENEBODY
SCLC-P
F


cg15618336
chr12: 52182759
SCN8A.GENEBODY
SCLC-P
R


cg15939973
chr17: 76419841
DNAH17.UTR3
SCLC-P
F
chr17: 76421441-
N_Shore







76421766


cg17301216
chr15: 89920348
LOC254559.TSS1500
SCLC-P
R
chr15: 89920793-
N_Shore







89922768


cg17730176
chr17: 27404126
TIAF1.TSS1500
SCLC-P
R
chr17: 27406753-
N_Shelf







27408059


cg18942985
chr2: 128523110
WDR33.GENEBODY
SCLC-P
R


cg19465165
chr2: 131130103
PTPN18.GENEBODY
SCLC-P
R
chr2: 131129718-
Island







131130511


cg19856701
chr17: 29549474
NF1.UTR3
SCLC-P
F


cg20886791
chr6: 33096055
HLA-DPB2.GENEBODY
SCLC-P
R


cg22158248
chr12: 112204136
ALDH2.TSS1500
SCLC-P
R
chr12: 112204498-
N_Shore







112204979


cg26306289
chr7: 33080571
NT5C3.TSS200
SCLC-P
F


cg27627524
chr8: 131325625
ASAP1.GENEBODY
SCLC-P
R


cg00848167
chr15: 89921898
LOC254559.GENEBODY
SCLC-P
F
chr15: 89920793-
Island







89922768


cg01227084
chr19: 2774520
SGTA.UTR5
SCLC-P
R
chr19: 2774196-2774550
Island


cg01685549
chr6: 33092097
HLA-DPB2.GENEBODY
SCLC-P
R


cg01767053
chr16: 85678884
KIAA0182.UTR5
SCLC-P
R
chr16: 85674843-
S_Shelf







85675192


cg01951712
chr6: 33081535
HLA-DPB2.GENEBODY
SCLC-P
F
chr6: 33084740-
N_Shelf







33084995


cg02388468
chr6: 33095664
HLA-DPB2.GENEBODY
SCLC-P
F


cg02470179
chr3: 31580476
STT3B.GENEBODY
SCLC-P
F


cg03766449
chr15: 89920918
LOC254559.TSS1500
SCLC-P
F
chr15: 89920793-
Island







89922768


cg03917138
chr17: 70120182
SOX9.GENEBODY
SCLC-P
F
chr17: 70120139-
Island







70120442


cg04918708
chr1: 204057900
SOX13.UTR5
SCLC-P
F


cg05427639
chr7: 33080496
NT5C3.EXON1
SCLC-P
R


cg06517794
chr1: 78180274
USP33.GENEBODY
SCLC-P
R


cg07586345
chr19: 2774332
SGTA.UTR5
SCLC-P
R
chr19: 2774196-2774550
Island


cg09787021
chr1: 25988486
MAN1C1.GENEBODY
SCLC-P
R


cg09825327
chr1: 211503219
TRAF5.UTR5
SCLC-P
F
chr1: 211500151-
S_Shelf







211500636


cg10327769
chr17: 43340243
LOC100133991.GENEBODY
SCLC-P
F
chr17: 43339124-
S_Shore







43339832


cg10657965
chr7: 101888125
CUX1.GENEBODY
SCLC-P
R
chr7: 101891665-
N_Shelf







101892634


cg11786476
chr6: 33096738
HLA-DPB2.GENEBODY
SCLC-P
R


cg12406391
chr1: 6520194
ESPN.GENEBODY
SCLC-P
F
chr1: 6520584-6521955
N_Shore


cg12873454
chr1: 14924611
KIAA1026.TSS1500
SCLC-P
R
chr1: 14924610-
Island







14925993


cg13077784
chr1: 201706363
NAV1.GENEBODY
SCLC-P
R
chr1: 201708787-
N_Shelf







201709429


cg13977526
chr9: 32384244
ACO1.TSS1500
SCLC-P
F
chr9: 32384420-
N_Shore







32384911


cg15019001
chr6: 33096303
HLA-DPB2.GENEBODY
SCLC-P
R


cg15826519
chr1: 19808575
CAPZB.GENEBODY
SCLC-P
F
chr1: 19811703-
N_Shelf







19812644


cg16072780
chr11: 93453897
SCARNA9.TSS1500
SCLC-P
F


cg16205850
chr15: 75118021
LMAN1L.UTR3
SCLC-P
R


cg18109571
chr6: 127835189
C6orf174.GENEBODY
SCLC-P
F
chr6: 127835928-
N_Shore







127836255


cg18198143
chr6: 33094306
HLA-DPB2.GENEBODY
SCLC-P
F


cg18474502
chr10: 124777194
ACADSB.GENEBODY
SCLC-P
R


cg18680328
chr10: 123868970
TACC2.GENEBODY
SCLC-P
R
chr10: 123872119-
N_Shelf







123873462


cg19046783
chr7: 99382086
CYP3A4.TSS1500
SCLC-P
R


cg20314331
chr2: 131129567
PTPN18.GENEBODY
SCLC-P
R
chr2: 131129718-
N_Shore







131130511


cg20567355
chr8: 52754434
PCMTD1.GENEBODY
SCLC-P
R


cg21516291
chr20: 44979100
SLC35C2.GENEBODY
SCLC-P
F


cg21955534
chrX: 15525514
BMX.EXON1
SCLC-P
F


cg22052010
chr20: 33541934
GSS.UTR5
SCLC-P
R
chr20: 33543082-
N_Shore







33543846


cg22888311
chr12: 80076443
PAWR.GENEBODY
SCLC-P
F


cg23538755
chr19: 2774549
SGTA.UTR5
SCLC-P
F
chr19: 2774196-2774550
Island


cg24156613
chrX: 39950501
BCOR.UTR5
SCLC-P
R
chrX: 39950899-
N_Shore







39951665


cg24180219
chr10: 105239190
CALHM3.TSS200
SCLC-P
R


cg25064331
chr7: 33080500
NT5C3.EXON1
SCLC-P
R


cg25474399
chr18: 3067624
MYOM1.GENEBODY
SCLC-P
F
chr18: 3067297-3067533
S_Shore


cg25759507
chr11: 12008553
DKK3.GENEBODY
SCLC-P
R


cg26086731
chr3: 169900468
PHC3.TSS1500
SCLC-P
F
chr3: 169898946-
S_Shore







169899626


cg26469011
chr10: 75886930
AP3M1.GENEBODY
SCLC-P
F


cg26536240
chr16: 89509760
ANKRD11.UTR5
SCLC-P
R


cg00350405
chr2: 128244940
IWS1.GENEBODY
SCLC-P
F


cg01541650
chr6: 157505968
ARID1B.GENEBODY
SCLC-P
R


cg02061660
chr5: 110088130
SLC25A46.GENEBODY
SCLC-P
F


cg02380236
chr15: 22383188
OR4N4.EXON1
SCLC-P
F


cg03233656
chr2: 65214625
SLC1A4.TSS1500
SCLC-P
F
chr2: 65215598-
N_Shore







65217212


cg04824189
chr7: 80142634
GNAT3.TSS1500
SCLC-P
F


cg05009111
chr20: 58520201
C20orf177.UTR3
SCLC-P
R


cg05366160
chr6: 33039481
HLA-DPA1.GENEBODY
SCLC-P
F


cg06614640
chr17: 80826697
TBCD.GENEBODY
SCLC-P
R
chr17: 80827970-
N_Shore







80828316


cg09142647
chr16: 75674568
KARS.GENEBODY
SCLC-P
R


cg10094078
chr19: 1467925
APC2.GENEBODY
SCLC-P
F
chr19: 1465206-1471241
Island


cg10297701
chr6: 32972902
HLA-DOA.UTR3
SCLC-P
F
chr6: 32975684-
N_Shelf







32975926


cg10604002
chr2: 131130131
PTPN18.GENEBODY
SCLC-P
R
chr2: 131129718-
Island







131130511


cg10725390
chr2: 66743000
MEIS1.GENEBODY
SCLC-P
F


cg12733040
chr22: 17303493
XKR3.TSS1500
SCLC-P
F


cg12748948
chr1: 22106295
USP48.GENEBODY
SCLC-P
F
chr1: 22109129-
N_Shelf







22110261


cg12815916
chr2: 131114432
PTPN18.GENEBODY
SCLC-P
F
chr2: 131113090-
S_Shore







131114277


cg13726789
chr8: 37678323
GPR124.GENEBODY
SCLC-P
F


cg13922121
chr11: 19575262
NAV2.GENEBODY
SCLC-P
F


cg15214229
chr20: 35275274
SLA2.TSS1500
SCLC-P
R


cg16296829
chr1: 154832535
KCNN3.TSS200
SCLC-P
R


cg16431810
chr7: 2420339
EIF3B.UTR3
SCLC-P
F
chr7: 2419808-2420340
Island


cg18451156
chr12: 133424373
CHFR.GENEBODY
SCLC-P
R


cg18963065
chrX: 15525321
BMX.UTR5
SCLC-P
F


cg21049501
chr17: 70120411
SOX9.GENEBODY
SCLC-P
F
chr17: 70120139-
Island







70120442


cg21121843
chr4: 3203982
HTT.GENEBODY
SCLC-P
R


cg21156320
chr12: 56112820
BLOC1S1.GENEBODY
SCLC-P
R
chr12: 56109798-
S_Shelf







56110298


cg04403809
chr20: 44686493
SLC12A5.UTR3
SCLC-P
R
chr20: 44685771-
Island







44687610


cg00538021
chr16: 12192263
SNX29.GENEBODY
SCLC-P
R


cg00712146
chr3: 65340538
MAGI1.UTR3
SCLC-P
R
chr3: 65342203-
N_Shore







65342884


cg01249653
chr6: 33095755
HLA-DPB2.GENEBODY
SCLC-P
F


cg03212228
chr19: 38395481
WDR87.UTR5
SCLC-P
F
chr19: 38397003-
N_Shore







38398165


cg03387092
chr3: 123493248
MYLK.GENEBODY
SCLC-P
R


cg04117530
chr1: 226187852
C1orf55.TSS1500
SCLC-P
R
chr1: 226186803-
S_Shore







226187336


cg04256886
chr2: 25603640
DTNB.GENEBODY
SCLC-P
R
chr2: 25599676-
S_Shelf







25599895


cg04351807
chr11: 36013639
LDLRAD3.GENEBODY
SCLC-P
R


cg04478905
chr21: 37915091
CLDN14.TSS200
SCLC-P
F


cg04998498
chr11: 113725687
USP28.GENEBODY
SCLC-P
F


cg05613017
chr12: 65589446
LEMD3.GENEBODY
SCLC-P
F


cg06234051
chr17: 70120541
SOX9.UTR3
SCLC-P
F
chr17: 70116274-
S_Shore







70119998


cg06532924
chr1: 247268238
ZNF669.TSS1500
SCLC-P
F
chr1: 247267179-
S_Shore







247267884


cg07069844
chr19: 1617027
TCF3.GENEBODY
SCLC-P
F
chr19: 1615202-1615812
S_Shore


cg07202461
chr18: 19406765
MIB1.GENEBODY
SCLC-P
F


cg07813851
chr1: 7466976
CAMTA1.GENEBODY
SCLC-P
F


cg08088222
chr12: 122070432
ORAI1.GENEBODY
SCLC-P
F


cg08948637
chr20: 62614493
PRPF6.GENEBODY
SCLC-P
R
chr20: 62612300-
S_Shore







62612787


cg10004079
chr17: 26372530
NLK.GENEBODY
SCLC-P
R
chr17: 26368586-
S_Shelf







26369133


cg10735599
chr6: 33081024
HLA-DPB2.GENEBODY
SCLC-P
F
chr6: 33084740-
N_Shelf







33084995


cg10932086
chr14: 90041348
PRO1768.TSS1500
SCLC-P
F


cg12255995
chr19: 1132537
SBNO2.GENEBODY
SCLC-P
R


cg12555369
chr10: 105153066
USMG5.UTR5
SCLC-P
R
chr10: 105155820-
N_Shelf







105156484


cg12577003
chr7: 2261337
MAD1L1.GENEBODY
SCLC-P
R


cg12582616
chr6: 15427489
JARID2.GENEBODY
SCLC-P
F


cg13058710
chr17: 70119609
SOX9.GENEBODY
SCLC-P
F
chr17: 70116274-
Island







70119998


cg13362033
chr1: 7018949
CAMTA1.GENEBODY
SCLC-P
F
chr1: 7022001-7022308
N_Shelf


cg13726166
chr17: 27403888
TIAF1.TSS1500
SCLC-P
F
chr17: 27406753-
N_Shelf







27408059


cg13738075
chr13: 114793125
RASA3.GENEBODY
SCLC-P
R


cg14373068
chr11: 1537765
HCCA2.GENEBODY
SCLC-P
F
chr11: 1536729-1536953
S_Shore


cg14521421
chr11: 8862019
ST5.UTR5
SCLC-P
R


cg14762436
chr7: 24917750
OSBPL3.GENEBODY
SCLC-P
F


cg17223866
chr1: 44794158
ERI3.GENEBODY
SCLC-P
F


cg18236734
chr3: 183817931
HTR3E.TSS200
SCLC-P
F


cg18714586
chr13: 30831499
KATNAL1.GENEBODY
SCLC-P
R


cg19232395
chr11: 8550221
STK33.UTR5
SCLC-P
R


cg19251161
chr10: 106094166
ITPRIP.TSS1500
SCLC-P
R
chr10: 106097595-
N_Shelf







106098556


cg19490899
chr6: 52855923
GSTA4.GENEBODY
SCLC-P
R
chr6: 52859565-
N_Shelf







52859767


cg19644145
chr7: 21488742
SP4.GENEBODY
SCLC-P
F


cg20288892
chr7: 82072332
CACNA2D1.GENEBODY
SCLC-P
R
chr7: 82072021-
Island







82073520


cg20706496
chr6: 112084071
FYN.UTR5
SCLC-P
R


cg22235258
chr11: 34675402
EHF.GENEBODY
SCLC-P
F


cg22736267
chr7: 148841524
ZNF398.UTR5
SCLC-P
F
chr7: 148844254-
N_Shelf







148845556


cg23025804
chr10: 29811659
SVIL.GENEBODY
SCLC-P
F


cg23794671
chr6: 32977580
HLA-DOA.TSS200
SCLC-P
F
chr6: 32975684-
S_Shore







32975926


cg23998903
chr2: 209048830
C2orf80.GENEBODY
SCLC-P
F


cg24223075
chr11: 119137279
CBL.GENEBODY
SCLC-P
F


cg24321688
chr19: 39393347
NFKBIB.GENEBODY
SCLC-P
F
chr19: 39395881-
N_Shelf







39396106


cg24904278
chr4: 3514709
LRPAP1.GENEBODY
SCLC-P
F
chr4: 3514537-3514848
Island


cg24918798
chr2: 103432687
TMEM182.UTR3
SCLC-P
R


cg25380514
chr3: 169900418
PHC3.TSS1500
SCLC-P
F
chr3: 169898946-
S_Shore







169899626


cg25649889
chr2: 171196296
MYO3B.GENEBODY
SCLC-P
F


cg25681122
chr3: 194832600
C3orf21.GENEBODY
SCLC-P
F


cg25848827
chr1: 7550111
CAMTA1.GENEBODY
SCLC-P
R


cg25977504
chr1: 247979157
OR14A16.TSS200
SCLC-P
R


cg00425764
chr16: 15949616
MYH11.UTR5
SCLC-P
R
chr16: 15950839-
N_Shore







15951266


cg00863378
chr16: 56549757
BBS2.GENEBODY
SCLC-P
R
chr16: 56553529-
N_Shelf







56554075


cg00946598
chr1: 44117093
KDM4A.UTR5
SCLC-P
F
chr1: 44115616-
S_Shore







44116309


cg01140395
chr15: 52570565
MIR1266.TSS1500
SCLC-P
F


cg01418162
chr1: 204891567
NFASC.UTR5
SCLC-P
R


cg01708014
chr14: 51299002
NIN.TSS1500
SCLC-P
R
chr14: 51296727-
S_Shore







51298477


cg01772439
chr5: 149012102
FLJ41603.UTR3
SCLC-P
R


cg01859360
chr17: 26990458
SUPT6H.UTR5
SCLC-P
R
chr17: 26988721-
S_Shore







26989391


cg01891209
chr1: 44401222
ARTN.TSS1500
SCLC-P
R
chr1: 44401757-
N_Shore







44402423


cg02362718
chr11: 133942581
JAM3.GENEBODY
SCLC-P
F
chr11: 133938850-
S_Shelf







133939681


cg02632809
chr7: 5336811
SLC29A4.GENEBODY
SCLC-P
R
chr7: 5336513-5336894
Island


cg04022912
chr16: 24864984
SLC5A11.UTR5
SCLC-P
F


cg04153082
chr8: 48325740
KIAA0146.GENEBODY
SCLC-P
F


cg04272613
chr14: 59721173
DAAM1.UTR5
SCLC-P
F


cg04694619
chr2: 242127759
ANO7.TSS200
SCLC-P
F


cg05995528
chr6: 33036495
HLA-DPA1.GENEBODY
SCLC-P
F


cg06821199
chr4: 779230
CPLX1.UTR3
SCLC-P
F
chr4: 778661-780592
Island


cg06985721
chr1: 55464653
BSND.EXON1
SCLC-P
F
chr1: 55462688-
S_Shore







55463010


cg08961287
chr15: 89919993
LOC254559.TSS1500
SCLC-P
F
chr15: 89920793-
N_Shore







89922768


cg09561830
chr13: 100007116
UBAC2.GENEBODY
SCLC-P
R


cg10042298
chr11: 78024311
GAB2.GENEBODY
SCLC-P
R


cg10471574
chr17: 70120318
SOX9.GENEBODY
SCLC-P
F
chr17: 70120139-
Island







70120442


cg10803321
chr1: 50629523
ELAVL4.GENEBODY
SCLC-P
R


cg10818986
chr1: 248083146
OR2T8.TSS1500
SCLC-P
R


cg11131599
chr1: 204224211
PLEKHA6.GENEBODY
SCLC-P
F
chr1: 204226544-
N_Shelf







204226908


cg12338214
chr10: 133783113
BNIP3.GENEBODY
SCLC-P
R


cg12499542
chr12: 53808156
SP1.UTR3
SCLC-P
R


cg12832726
chr11: 68096165
LRP5.GENEBODY
SCLC-P
F


cg13375479
chr7: 133984347
SLC35B4.GENEBODY
SCLC-P
F


cg13551330
chr9: 32388149
ACO1.UTR5
SCLC-P
R
chr9: 32384420-
S_Shelf







32384911


cg13696135
chr12: 49396782
PRKAG1.GENEBODY
SCLC-P
R
chr12: 49393139-
S_Shelf







49393361


cg14200678
chr9: 123380343
MEGF9.GENEBODY
SCLC-P
F


cg14373797
chr6: 33053576
HLA-DPB1.GENEBODY
SCLC-P
R


cg14880894
chr4: 78697859
CNOT6L.GENEBODY
SCLC-P
R


cg15661715
chr7: 151401947
PRKAG2.GENEBODY
SCLC-P
F


cg15955522
chr5: 143553445
KCTD16.UTR5
SCLC-P
R
chr5: 143549939-
S_Shelf







143550333


cg16083838
chr11: 2889809
KCNQ1DN.TSS1500
SCLC-P
R
chr11: 2890388-2891337
N_Shore


cg16189995
chr2: 226330770
KIAA1486.GENEBODY
SCLC-P
R


cg17491228
chr11: 64476089
NRXN2.GENEBODY
SCLC-P
F
chr11: 64478843-
N_Shelf







64479598


cg17851748
chr12: 83264140
TMTC2.GENEBODY
SCLC-P
R


cg18063824
chr4: 54075042
SCFD2.GENEBODY
SCLC-P
F


cg18282011
chr1: 1590447
CDK11B.GENEBODY
SCLC-P
F
chr1: 1590073-1590942
Island


cg19083007
chr6: 46293862
RCAN2.TSS1500
SCLC-P
R


cg19740679
chr1: 21930180
RAP1GAP.GENEBODY
SCLC-P
R
chr1: 21930179-
Island







21930380


cg20535805
chr19: 18420735
LSM4.GENEBODY
SCLC-P
F
chr19: 18420489-
Island







18420736


cg20643029
chr21: 37915044
CLDN14.TSS200
SCLC-P
F


cg21039196
chr6: 71435620
SMAP1.GENEBODY
SCLC-P
F


cg21221516
chr3: 183950129
VWA5B2.GENEBODY
SCLC-P
F
chr3: 183947040-
S_Shore







183948801


cg21350778
chr17: 64297603
PRKCA.TSS1500
SCLC-P
R
chr17: 64298047-
N_Shore







64299617


cg23034373
chr21: 37915354
CLDN14.UTR5
SCLC-P
F


cg23200572
chr6: 33096501
HLA-DPB2.GENEBODY
SCLC-P
R


cg24008634
chr10: 13694895
FRMD4A.GENEBODY
SCLC-P
R
chr10: 13698562-
N_Shelf







13699540


cg24401199
chr19: 3159786
GNA15.GENEBODY
SCLC-P
F
chr19: 3162841-3163161
N_Shelf


cg24677302
chr14: 75922163
JDP2.GENEBODY
SCLC-P
R


cg24987745
chr2: 17819167
VSNL1.GENEBODY
SCLC-P
R


cg25119261
chr6: 33081351
HLA-DPB2.GENEBODY
SCLC-P
R
chr6: 33084740-
N_Shelf







33084995


cg25243171
chr2: 23914356
KLHL29.GENEBODY
SCLC-P
R
chr2: 23913308-
S_Shore







23913569


cg26886855
chr8: 10694831
PINX1.GENEBODY
SCLC-P
R
chr8: 10697016-
N_Shelf







10697634


cg26949694
chr11: 27742060
BDNF.GENEBODY
SCLC-P
R
chr11: 27742059-
Island







27742273


cg27636594
chr7: 38767436
VPS41.GENEBODY
SCLC-P
R


cg01208614
chr5: 141031443
FCHSD1.TSS1500
SCLC-P
R
chr5: 141030918-
S_Shore







141031177


cg02389877
chr15: 68583600
FEM1B.UTR3
SCLC-P
F


cg02882004
chr2: 201334663
SPATS2L.GENEBODY
SCLC-P
R


cg04077303
chr1: 236308094
GPR137B.GENEBODY
SCLC-P
R
chr1: 236305534-
S_Shore







236306674


cg04576847
chr17: 12623611
MYOCD.GENEBODY
SCLC-P
R


cg06879534
chr4: 39447437
KLB.GENEBODY
SCLC-P
F
chr4: 39448184-
N_Shore







39449054


cg07010146
chr10: 105239205
CALHM3.TSS1500
SCLC-P
R


cg07304186
chr6: 38112278
ZFAND3.GENEBODY
SCLC-P
R


cg08759770
chr12: 51849767
SLC4A8.GENEBODY
SCLC-P
F


cg13339454
chr2: 242127690
ANO7.TSS1500
SCLC-P
F


cg14080888
chr9: 130712990
FAM102A.UTR5
SCLC-P
F


cg18477771
chr11: 120195466
TMEM136.TSS1500
SCLC-P
F
chr11: 120195805-
N_Shore







120196372


cg19377250
chr7: 100463206
SLC12A9.GENEBODY
SCLC-P
F
chr7: 100463758-
N_Shore







100464146


cg20272287
chr17: 19247905
MIR1180.TSS200
SCLC-P
F
chr17: 19247785-
Island







19248069


cg21265278
chr1: 179057067
TOR3A.GENEBODY
SCLC-P
F


cg23541975
chr17: 75143184
SEC14L1.GENEBODY
SCLC-P
R


cg00552822
chr15: 22368443
LOC727924.GENEBODY
SCLC-P
R


cg00796611
chr1: 206603444
SRGAP2.GENEBODY
SCLC-P
R


cg01367339
chr3: 44962718
ZDHHC3.GENEBODY
SCLC-P
R


cg01638185
chr17: 64530027
PRKCA.GENEBODY
SCLC-P
R


cg01668281
chr21: 37915281
CLDN14.UTR5
SCLC-P
R


cg01715699
chr13: 99209655
STK24.GENEBODY
SCLC-P
R


cg01854491
chr8: 144815021
FAM83H.UTR5
SCLC-P
F
chr8: 144815203-
N_Shore







144816518


cg02246992
chr17: 29158363
ATAD5.TSS1500
SCLC-P
F
chr17: 29158878-
N_Shore







29159423


cg02370478
chrX: 106241676
MORC4.GENEBODY
SCLC-P
R
chrX: 106242506-
N_Shore







106243593


cg02544829
chr8: 95385408
RAD54B.GENEBODY
SCLC-P
F


cg03332109
chr11: 126360468
KIRREL3.GENEBODY
SCLC-P
F


cg04086197
chr14: 104205071
PPP1R13B.GENEBODY
SCLC-P
R
chr14: 104205070-
Island







104205329


cg04236786
chr8: 41580903
ANK1.GENEBODY
SCLC-P
R
chr8: 41583135-
N_Shelf







41583524


cg04920416
chr17: 35336293
AATF.GENEBODY
SCLC-P
R


cg05490757
chr17: 77130342
HRNBP3.UTR5
SCLC-P
F
chr17: 77133927-
N_Shelf







77134175


cg06927775
chr17: 40609423
ATP6VOA1.TSS1500
SCLC-P
R
chr17: 40610746-
N_Shore







40611032


cg07481360
chr3: 196902551
DLG1.GENEBODY
SCLC-P
F


cg07535740
chr19: 5915494
CAPS.UTR3
SCLC-P
F
chr19: 5915007-5915301
S_Shore


cg08707617
chrX: 39944352
BCOR.UTR5
SCLC-P
R
chrX: 39942756-
S_Shore







39943419


cg08760402
chr6: 33036486
HLA-DPA1.GENEBODY
SCLC-P
R


cg09002351
chr16: 75204945
ZFP1.UTR3
SCLC-P
F


cg09203240
chr11: 68115891
LRP5.GENEBODY
SCLC-P
R
chr11: 68115317-
S_Shore







68115726


cg10674511
chrX: 78003091
LPAR4.TSS200
SCLC-P
F


cg10808783
chr19: 1467921
APC2.GENEBODY
SCLC-P
F
chr19: 1465206-1471241
Island


cg11336987
chr3: 123974913
KALRN.GENEBODY
SCLC-P
F


cg12700788
chr17: 72348160
KIF19.GENEBODY
SCLC-P
R
chr17: 72347924-
Island







72348322


cg12892471
chr12: 50616779
LIMA1.GENEBODY
SCLC-P
F


cg13356324
chr1: 228332502
GUK1.UTR5
SCLC-P
R
chr1: 228327508-
S_Shelf







228328560


cg14353201
chr11: 67448395
ALDH3B2.UTR5
SCLC-P
F


cg15770046
chr19: 35764710
USF2.GENEBODY
SCLC-P
F
chr19: 35760457-
S_Shelf







35760865


cg16712103
chr1: 193150499
B3GALT2.GENEBODY
SCLC-P
F


cg16831185
chr17: 29158530
ATAD5.TSS1500
SCLC-P
F
chr17: 29158878-
N_Shore







29159423


cg17219729
chr1: 36937845
CSF3R.GENEBODY
SCLC-P
F


cg17582782
chr15: 57592438
LOC283663.TSS200
SCLC-P
F


cg17649671
chr10: 89298596
MINPP1.GENEBODY
SCLC-P
F


cg18106482
chr11: 2680314
KCNQ1.GENEBODY
SCLC-P
R


cg18993757
chr17: 4889754
CAMTA2.UTR5
SCLC-P
F
chr17: 4890282-4890991
N_Shore


cg19113599
chr15: 99683042
TTC23.GENEBODY
SCLC-P
R


cg19296405
chr19: 18368483
KIAA1683.GENEBODY
SCLC-P
R
chr19: 18368482-
Island







18368911


cg19533977
chr17: 57719682
CLTC.GENEBODY
SCLC-P
F


cg19601328
chr17: 43368729
MAP3K14.UTR5
SCLC-P
R


cg19909036
chr15: 90294776
MESP1.TSS1500
SCLC-P
F
chr15: 90293221-
S_Shore







90294733


cg20664654
chrX: 153169465
AVPR2.TSS1500
SCLC-P
R


cg22057240
chr5: 6755843
POLS.UTR3
SCLC-P
R
chr5: 6755104-6755387
S_Shore


cg22675922
chr11: 2889840
KCNQ1DN.TSS1500
SCLC-P
R
chr11: 2890388-2891337
N_Shore


cg24051242
chr11: 68096138
LRP5.GENEBODY
SCLC-P
R


cg24063043
chr17: 64567021
PRKCA.GENEBODY
SCLC-P
R


cg24420432
chr7: 101518619
CUX1.GENEBODY
SCLC-P
F


cg27050612
chr17: 46133198
NFE2L1.GENEBODY
SCLC-P
F
chr17: 46136649-
N_Shelf







46136969


cg27064928
chrX: 146996911
ASFMR1.GENEBODY
SCLC-P
F
chrX: 146993091-
S_Shelf







146994200


cg01966522
chr3: 126236504
UROC1.EXON1
SCLC-P
R


cg04619304
chr12: 24434537
SOX5.UTR5
SCLC-P
R


cg05043047
chr8: 144583910
ZC3H3.GENEBODY
SCLC-P
R


cg05169160
chr2: 178484487
TTC30A.TSS1500
SCLC-P
R
chr2: 178483233-
S_Shore







178483783


cg05733361
chr15: 85524456
PDE8A.TSS1500
SCLC-P
R
chr15: 85523512-
Island







85525865


cg06895124
chr8: 141588750
EIF2C2.GENEBODY
SCLC-P
R


cg07178896
chr16: 50238554
PAPD5.GENEBODY
SCLC-P
F


cg09038267
chr10: 104524861
C10orf26.GENEBODY
SCLC-P
F


cg10369242
chr12: 52625486
KRT7.TSS1500
SCLC-P
R
chr12: 52626793-
N_Shore







52627577


cg11678118
chr6: 122935372
PKIB.UTR5
SCLC-P
F
chr6: 122931153-
S_Shelf







122931705


cg12100006
chr11: 35964190
LDLRAD3.TSS1500
SCLC-P
R
chr11: 35965642-
N_Shore







35966454


cg12738079
chrX: 153169469
AVPR2.TSS1500
SCLC-P
R


cg12745145
chr7: 2261452
MAD1L1.GENEBODY
SCLC-P
F


cg13259357
chr3: 191109928
CCDC50.UTR3
SCLC-P
F


cg14356799
chr6: 33044345
HLA-DPB1.GENEBODY
SCLC-P
R


cg14981137
chr5: 50678697
ISL1.TSS1500
SCLC-P
R
chr5: 50678632-
Island







50679375


cg16235962
chr11: 118754507
CXCR5.TSS200
SCLC-P
F


cg18907656
chr8: 30888925
PURG.GENEBODY
SCLC-P
F


cg19407960
chr6: 33094829
HLA-DPB2.GENEBODY
SCLC-P
F


cg20738500
chr15: 89921156
LOC254559.TSS200
SCLC-P
F
chr15: 89920793-
Island







89922768


cg20851325
chrX: 153169432
AVPR2.TSS1500
SCLC-P
F


cg21211730
chr19: 45279770
CBLC.TSS1500
SCLC-P
F
chr19: 45281133-
N_Shore







45281355


cg21608489
chr19: 42637137
POU2F2.TSS1500
SCLC-P
R
chr19: 42637277-
N_Shore







42637684


cg22338118
chr7: 94536003
PPP1R9A.TSS1500
SCLC-P
F
chr7: 94536849-
N_Shore







94537477


cg24644448
chr2: 114383268
RPL23AP7.GENEBODY
SCLC-P
R
chr2: 114384589-
N_Shore







114385133


cg25694790
chr20: 17582752
DSTN.GENEBODY
SCLC-P
F


cg26067647
chr19: 1420404
DAZAP1.GENEBODY
SCLC-P
F
chr19: 1419751-1420405
Island


cg26643856
chr6: 32977349
HLA-DOA.EXON1
SCLC-P
R
chr6: 32975684-
S_Shore







32975926


cg27500983
chr20: 34700201
EPB41L1.TSS200
SCLC-P
R


cg00166343
chr17: 29150100
CRLF3.GENEBODY
SCLC-P
R
chr17: 29151481-
N_Shore







29151901


cg01091565
chr15: 90294762
MESP1.TSS1500
SCLC-P
F
chr15: 90293221-
S_Shore







90294733


cg01755009
chr1: 247978690
OR14A16.EXON1
SCLC-P
F


cg02347367
chr6: 109250017
ARMC2.GENEBODY
SCLC-P
R


cg02397571
chr8: 28175463
PNOC.UTR5
SCLC-P
F


cg06544652
chr1: 248006259
OR11L1.TSS1500
SCLC-P
R


cg08097973
chr11: 71793051
LRTOMT.UTR5
SCLC-P
R
chr11: 71791385-
S_Shore







71791960


cg08822075
chr7: 26193607
NFE2L3.GENEBODY
SCLC-P
R
chr7: 26191794-
S_Shore







26192757


cg10057033
chr8: 41737893
ANK1.GENEBODY
SCLC-P
F
chr8: 41733535-
S_Shelf







41733911


cg11301657
chr12: 3749918
EFCAB4B.GENEBODY
SCLC-P
R


cg11437465
chr6: 33036958
HLA-DPA1.GENEBODY
SCLC-P
F


cg12704098
chr3: 56838665
ARHGEF3.GENEBODY
SCLC-P
F
chr3: 56835650-
S_Shelf







56836210


cg15642209
chr17: 66290505
ARSG.UTR5
SCLC-P
R
chr17: 66286541-
S_Shore







66288532


cg15841865
chr7: 143173551
TAS2R41.TSS1500
SCLC-P
F


cg16027403
chr1: 247978791
OR14A16.EXON1
SCLC-P
F


cg16527552
chr19: 42816045
TMEM145.TSS1500
SCLC-P
R
chr19: 42817412-
N_Shore







42818038


cg17138415
chr12: 107259568
RIC8B.GENEBODY
SCLC-P
R


cg17395184
chr15: 42750462
ZFP106.TSS1500
SCLC-P
R


cg19333963
chr19: 1467979
APC2.GENEBODY
SCLC-P
F
chr19: 1465206-1471241
Island


cg19494588
chr5: 146195103
PPP2R2B.GENEBODY
SCLC-P
R


cg22392325
chr1: 7049418
CAMTA1.GENEBODY
SCLC-P
F


cg23746600
chr6: 160403181
IGF2R.GENEBODY
SCLC-P
F


cg25019648
chr17: 72353261
BTBD17.GENEBODY
SCLC-P
R
chr17: 72352827-
Island







72353798


cg25444002
chr13: 102520143
FGF14.GENEBODY
SCLC-P
R


cg27121870
chr11: 134257030
B3GAT1.GENEBODY
SCLC-P
R
chr11: 134257428-
N_Shore







134257631


cg27319536
chr5: 146260901
PPP2R2B.UTR5
SCLC-P
R
chr5: 146257346-
S_Shelf







146258575


cg27382459
chr2: 145237379
ZEB2.GENEBODY
SCLC-P
F


cg27639080
chr12: 49960363
MCRS1.GENEBODY
SCLC-P
R
chr12: 49961630-
N_Shore







49962219


cg00762029
chr4: 185317438
IRF2.GENEBODY
SCLC-P
R


cg01217406
chr15: 23013480
NIPA2.GENEBODY
SCLC-P
R


cg01220513
chrX: 19902129
SH3KBP1.GENEBODY
SCLC-P
F
chrX: 19905027-
N_Shelf







19906557


cg01620165
chr12: 113530915
DTX1.GENEBODY
SCLC-P
R
chr12: 113530914-
Island







113531476


cg01708377
chr6: 1686746
GMDS.GENEBODY
SCLC-P
R


cg02291620
chr1: 233365140
PCNXL2.GENEBODY
SCLC-P
F


cg02394186
chr1: 6088550
KCNAB2.UTR5
SCLC-P
F
chr1: 6086244-6086494
S_Shelf


cg03389720
chr16: 8780048
ABAT.UTR5
SCLC-P
R


cg04021887
chr2: 10566989
HPCAL1.UTR3
SCLC-P
R
chr2: 10566889-
Island







10567148


cg05058976
chr16: 3637956
BTBD12.GENEBODY
SCLC-P
R
chr16: 3639092-3639306
N_Shore


cg05157251
chr18: 57566460
PMAIP1.TSS1500
SCLC-P
R
chr18: 57566866-
N_Shore







57567723


cg05407550
chrX: 154250784
F8.EXON1
SCLC-P
R


cg05621843
chr9: 97806397
C9orf3.GENEBODY
SCLC-P
F
chr9: 97807450-
N_Shore







97807694


cg07038822
chr11: 125830798
CDON.UTR3
SCLC-P
F


cg07507418
chr6: 42372284
TRERF1.UTR5
SCLC-P
R


cg07716663
chr19: 42636625
POU2F2.UTR5
SCLC-P
F
chr19: 42637277-
N_Shore







42637684


cg07768372
chr5: 14509008
TRIO.UTR3
SCLC-P
F


cg07849009
chr7: 105663410
FLJ23834.GENEBODY
SCLC-P
F


cg07960154
chr17: 37760198
NEUROD2.UTR3
SCLC-P
F
chr17: 37761691-
N_Shore







37763551


cg08438392
chr2: 27708644
IFT172.GENEBODY
SCLC-P
R
chr2: 27712554-
N_Shelf







27712842


cg09016768
chr11: 118982033
C2CD2L.GENEBODY
SCLC-P
F
chr11: 118977878-
S_Shelf







118978785


cg09640202
chr2: 131101440
IMP4.GENEBODY
SCLC-P
R
chr2: 131099469-
S_Shore







131100863


cg10090761
chr19: 1468466
APC2.GENEBODY
SCLC-P
F
chr19: 1465206-1471241
Island


cg11650039
chrX: 15525325
BMX.UTR5
SCLC-P
R


cg12110887
chr19: 11096925
SMARCA4.GENEBODY
SCLC-P
R
chr19: 11098395-
N_Shore







11098609


cg12184624
chr10: 105239164
CALHM3.TSS200
SCLC-P
F


cg12426293
chr18: 8612540
RAB12.GENEBODY
SCLC-P
F
chr18: 8608763-8610370
S_Shelf


cg12858166
chr6: 33033176
HLA-DPA1.UTR3
SCLC-P
R


cg13027851
chr2: 102433793
MAP4K4.GENEBODY
SCLC-P
F


cg13403121
chr7: 148963719
ZNF783.GENEBODY
SCLC-P
R
chr7: 148958858-
S_Shelf







148959891


cg15076824
chr1: 159685185
CRP.TSS1500
SCLC-P
F


cg15795819
chr8: 39328433
ADAM3A.GENEBODY
SCLC-P
R


cg16175713
chr6: 46617172
CYP39A1.GENEBODY
SCLC-P
F
chr6: 46620541-
N_Shelf







46621189


cg16430279
chr1: 1266504
TAS1R3.TSS1500
SCLC-P
F
chr1: 1267085-1267286
N_Shore


cg18457491
chr10: 104829517
CNNM2.GENEBODY
SCLC-P
R


cg18586851
chr20: 31332353
COMMD7.TSS1500
SCLC-P
R
chr20: 31330957-
S_Shore







31331410


cg19237600
chr7: 99564474
AZGP1.UTR3
SCLC-P
R


cg19305488
chr19: 1468359
APC2.GENEBODY
SCLC-P
F
chr19: 1465206-1471241
Island


cg19861842
chr8: 22855745
RHOBTB2.GENEBODY
SCLC-P
R
chr8: 22856800-
N_Shore







22857728


cg20058937
chr7: 5336543
SLC29A4.GENEBODY
SCLC-P
R
chr7: 5336513-5336894
Island


cg20668952
chr15: 75082885
CSK.UTR5
SCLC-P
F


cg20927312
chr3: 14443473
SLC6A6.TSS1500
SCLC-P
R
chr3: 14443629-
N_Shore







14444577


cg21702431
chr17: 19617084
SLC47A2.GENEBODY
SCLC-P
R
chr17: 19617083-
Island







19617424


cg23750365
chr6: 33043072
HLA-DPB1.TSS1500
SCLC-P
F


cg24532476
chr12: 133424566
CHFR.GENEBODY
SCLC-P
F


cg24686845
chr12: 94698752
PLXNC1.GENEBODY
SCLC-P
F


cg25052933
chr6: 33052888
HLA-DPB1.GENEBODY
SCLC-P
F


cg25087423
chr11: 118754535
CXCR5.TSS200
SCLC-P
R


cg25255988
chr11: 75428927
MOGAT2.TSS200
SCLC-P
R


cg25901444
chr7: 5336713
SLC29A4.GENEBODY
SCLC-P
R
chr7: 5336513-5336894
Island


cg26074140
chr1: 44401309
ARTN.TSS1500
SCLC-P
F
chr1: 44401757-
N_Shore







44402423


cg26300785
chr10: 81075492
ZMIZ1.UTR3
SCLC-P
F


cg26385743
chr2: 131101463
IMP4.GENEBODY
SCLC-P
R
chr2: 131099469-
S_Shore







131100863


cg26455386
chr17: 16999983
MPRIP.GENEBODY
SCLC-P
R


cg26576576
chr1: 214627705
PTPN14.GENEBODY
SCLC-P
R


cg27134386
chr4: 46392485
GABRA2.TSS1500
SCLC-P
R
chr4: 46391903-
Island







46392572


cg27407935
chr17: 17723235
SREBF1.GENEBODY
SCLC-P
F
chr17: 17726855-
N_Shelf







17727282


cg00457932
chr15: 28145216
OCA2.GENEBODY
SCLC-P
F
chr15: 28147925-
N_Shelf







28148465


cg03402235
chr15: 42749336
ZFP106.EXON1
SCLC-P
F


cg04245374
chr1: 168150977
TIPRL.GENEBODY
SCLC-P
F
chr1: 168147963-
S_Shelf







168148637


cg05571310
chr17: 72350354
KIF19.GENEBODY
SCLC-P
R
chr17: 72350346-
Island







72350711


cg06253072
chr6: 33679850
C6orf125.TSS1500
SCLC-P
F
chr6: 33679158-
S_Shore







33679701


cg07209550
chr5: 79070077
CMYA5.GENEBODY
SCLC-P
R


cg09888186
chr1: 183782195
RGL1.GENEBODY
SCLC-P
R


cg10294240
chr14: 96686415
BDKRB2.UTR5
SCLC-P
R


cg12194594
chr13: 113426250
ATP11A.GENEBODY
SCLC-P
R
chr13: 113424898-
S_Shore







113425105


cg13432241
chr4: 154389285
KIAA0922.GENEBODY
SCLC-P
F
chr4: 154386834-
S_Shore







154388183


cg17890764
chr3: 52864816
ITIH4.TSS200
SCLC-P
R


cg18491744
chr8: 41580834
ANK1.GENEBODY
SCLC-P
F
chr8: 41583135-
N_Shelf







41583524


cg20069765
chr6: 33036464
HLA-DPA1.GENEBODY
SCLC-P
R


cg21670451
chr5: 139781334
ANKHD1.TSS200
SCLC-P
F
chr5: 139780307-
Island







139782108


cg23272088
chr11: 2504813
KCNQ1.GENEBODY
SCLC-P
R


cg25227866
chr17: 71489530
SDK2.GENEBODY
SCLC-P
R


cg00093829
chr10: 6247101
PFKFB3.GENEBODY
SCLC-P
F
chr10: 6242975-6246457
S_Shore


cg01027750
chr19: 42636639
POU2F2.TSS200
SCLC-P
F
chr19: 42637277-
N_Shore







42637684


cg02782292
chr4: 144433846
SMARCA5.TSS1500
SCLC-P
F
chr4: 144434249-
N_Shore







144435343


cg03040622
chr7: 5536937
MIR589.TSS1500
SCLC-P
F
chr7: 5539957-5541567
N_Shelf


cg03101058
chr17: 71258936
CPSF4L.TSS1500
SCLC-P
R


cg03499581
chr15: 78384868
SH2D7.TSS200
SCLC-P
R


cg04398759
chr1: 203101066
ADORA1.GENEBODY
SCLC-P
R
chr1: 203097233-
S_Shelf







203097496


cg04502517
chr20: 62564156
DNAJC5.UTR3
SCLC-P
R
chr20: 62562545-
S_Shore







62562862


cg04908961
chr13: 92003278
MIR17HG.GENEBODY
SCLC-P
F
chr13: 91999541-
S_Shore







92001441


cg05030172
chr19: 2078510
MOBKL2A.GENEBODY
SCLC-P
F
chr19: 2078162-2078511
Island


cg05137443
chr6: 33094069
HLA-DPB2.GENEBODY
SCLC-P
F


cg05299486
chr17: 40609380
ATP6VOA1.TSS1500
SCLC-P
R
chr17: 40610746-
N_Shore







40611032


cg05451388
chr3: 183817678
HTR3E.TSS1500
SCLC-P
F


cg05887270
chr1: 26129627
SEPN1.GENEBODY
SCLC-P
R


cg07097026
chr6: 44257942
TCTE1.UTR5
SCLC-P
F
chr6: 44253897-
S_Shelf







44254150


cg07151747
chr2: 158977473
UPP2.GENEBODY
SCLC-P
F


cg07992044
chr11: 68096049
LRP5.GENEBODY
SCLC-P
F


cg08402572
chr2: 97510201
ANKRD23.TSS1500
SCLC-P
F


cg10097316
chr12: 7966784
SLC2A14.UTR3
SCLC-P
R


cg11356398
chr10: 133783182
BNIP3.GENEBODY
SCLC-P
F


cg11891522
chr5: 61605247
KIF2A.GENEBODY
SCLC-P
F
chr5: 61601617-
S_Shelf







61602930


cg12131414
chr17: 72352968
BTBD17.GENEBODY
SCLC-P
F
chr17: 72352827-
Island







72353798


cg12524428
chr5: 146268595
PPP2R2B.UTR5
SCLC-P
F


cg12674490
chr6: 31587470
BAT2.TSS1500
SCLC-P
R
chr6: 31587779-
N_Shore







31589024


cg12738981
chr1: 155828357
SYT11.TSS1500
SCLC-P
R
chr1: 155829109-
N_Shore







155829431


cg13187009
chr20: 55965497
RBM38.TSS1500
SCLC-P
R
chr20: 55966212-
N_Shore







55966964


cg13277337
chr2: 240265810
HDAC4.GENEBODY
SCLC-P
R


cg13594542
chr9: 138850547
UBAC1.GENEBODY
SCLC-P
R
chr9: 138852639-
N_Shelf







138853439


cg13925678
chr19: 3522946
FZR1.UTR5
SCLC-P
F


cg14095761
chr9: 35713238
TLN1.GENEBODY
SCLC-P
F


cg14168316
chr9: 127642782
GOLGA1.UTR3
SCLC-P
R


cg14173476
chr17: 19190476
EPN2.UTR5
SCLC-P
F


cg15031661
chr1: 240256603
FMN2.EXON1
SCLC-P
F
chr1: 240254959-
Island







240257063


cg15844109
chrX: 78003205
LPAR4.EXON1
SCLC-P
F


cg16054907
chr22: 50706065
MAPK11.GENEBODY
SCLC-P
R
chr22: 50705406-
Island







50706553


cg16518986
chr7: 157511420
PTPRN2.GENEBODY
SCLC-P
F


cg17297045
chr12: 125581343
AACS.GENEBODY
SCLC-P
R
chr12: 125578348-
S_Shelf







125578588


cg17547928
chr4: 737930
PCGF3.GENEBODY
SCLC-P
F
chr4: 738424-741517
N_Shore


cg17846127
chr15: 89940505
LOC254559.GENEBODY
SCLC-P
R
chr15: 89942592-
N_Shelf







89943853


cg18183642
chr1: 44497694
SLC6A9.TSS1500
SCLC-P
F
chr1: 44495629-
S_Shore







44497112


cg18315680
chr1: 154833117
KCNN3.GENEBODY
SCLC-P
R


cg18927185
chr6: 33091634
HLA-DPB2.GENEBODY
SCLC-P
F


cg19062108
chr12: 57630834
NDUFA4L2.GENEBODY
SCLC-P
R
chr12: 57631932-
N_Shore







57634578


cg19482842
chr2: 16790314
FAM49A.UTR5
SCLC-P
F


cg19710814
chr6: 33091596
HLA-DPB2.GENEBODY
SCLC-P
R


cg19995654
chr12: 66628777
IRAK3.GENEBODY
SCLC-P
R


cg20574732
chr7: 158277801
PTPRN2.GENEBODY
SCLC-P
F
chr7: 158277603-
Island







158278027


cg20643991
chr5: 121690136
SNCAIP.UTR5
SCLC-P
F


cg21542666
chr1: 248005715
OR11L1.TSS1500
SCLC-P
R


cg21570811
chr4: 3362574
RGS12.GENEBODY
SCLC-P
F
chr4: 3365194-3365415
N_Shelf


cg21751684
chr15: 89920887
LOC254559.TSS1500
SCLC-P
R
chr15: 89920793-
Island







89922768


cg21830221
chr1: 42334284
HIVEP3.UTR5
SCLC-P
F


cg22646210
chr11: 72380726
PDE2A.TSS1500
SCLC-P
F


cg23105863
chr14: 101011318
BEGAIN.GENEBODY
SCLC-P
F
chr14: 101012840-
N_Shore







101013117


cg23331433
chr6: 33039606
HLA-DPA1.GENEBODY
SCLC-P
F


cg23502492
chr17: 42394379
RUNDC3A.GENEBODY
SCLC-P
R
chr17: 42392323-
S_Shore







42393079


cg24940706
chr19: 1648682
TCF3.GENEBODY
SCLC-P
F
chr19: 1646117-1646713
S_Shore


cg25057035
chr6: 33053889
HLA-DPB1.GENEBODY
SCLC-P
R


cg25516633
chr8: 101315846
RNF19A.TSS1500
SCLC-P
F


cg26013412
chr1: 247094486
AHCTF1.GENEBODY
SCLC-P
R
chr1: 247094485-
Island







247095667


cg26164712
chr11: 118754565
CXCR5.UTR5
SCLC-P
F


cg26283963
chr7: 29330752
CHN2.GENEBODY
SCLC-P
F


cg26603629
chr7: 2752217
AMZ1.GENEBODY
SCLC-P
F


cg27184903
chr15: 29285727
APBA2.UTR5
SCLC-P
F


cg27191457
chr15: 69105133
ANP32A.GENEBODY
SCLC-P
F


cg27244524
chr3: 38494523
LOC100128640.GENEBODY
SCLC-P
F
chr3: 38495088-
N_Shore







38497151


cg27661104
chr2: 232645033
PDE6D.GENEBODY
SCLC-P
F
chr2: 232645313-
N_Shore







232646505


cg02982614
chr11: 89391479
FOLH1B.TSS1500
SCLC-P
R


cg12348588
chr17: 72352897
BTBD17.GENEBODY
SCLC-P
R
chr17: 72352827-
Island







72353798


cg13993358
chr5: 176304275
UNC5A.GENEBODY
SCLC-P
R
chr5: 176304965-
N_Shore







176305166


cg19567891
chr15: 89921083
LOC254559.TSS200
SCLC-P
F
chr15: 89920793-
Island







89922768


cg20371142
chr20: 17295221
PCSK2.GENEBODY
SCLC-P
F
chr20: 17296125-
N_Shore







17296531


cg20745419
chr1: 151696417
C1orf230.GENEBODY
SCLC-P
F
chr1: 151693991-
S_Shelf







151694282


cg24953213
chr5: 172140
PLEKHG4B.GENEBODY
SCLC-P
R
chr5: 169578-169798
S_Shelf


cg00088251
chr1: 1449754
ATAD3A.UTR5
SCLC-P
R
chr1: 1446878-1448205
S_Shore


cg00481644
chr15: 89921158
LOC254559.TSS200
SCLC-P
F
chr15: 89920793-
Island







89922768


cg00547530
chr16: 3559687
CLUAP1.GENEBODY
SCLC-P
F


cg00863271
chr17: 76798776
USP36.GENEBODY
SCLC-P
F
chr17: 76798154-
S_Shore







76798461


cg01011403
chr4: 56500362
NMU.GENEBODY
SCLC-P
F
chr4: 56501912-
N_Shore







56502523


cg01476047
chr10: 73974007
ASCC1.UTR5
SCLC-P
F
chr10: 73975671-
N_Shore







73976115


cg01477971
chr2: 103405951
TMEM182.GENEBODY
SCLC-P
R


cg01663696
chr12: 7942817
NANOG.GENEBODY
SCLC-P
F


cg01833923
chr17: 47286719
GNGT2.EXON1
SCLC-P
R


cg02140508
chr12: 4659038
RAD51AP1.GENEBODY
SCLC-P
F


cg02478836
chr22: 47510037
TBC1D22A.GENEBODY
SCLC-P
F
chr22: 47513202-
N_Shelf







47513585


cg03366884
chr17: 8844506
PIK3R5.UTR5
SCLC-P
R


cg03368665
chr11: 89819442
UBTFL1.EXON1
SCLC-P
R


cg03450107
chr1: 41980863
HIVEP3.GENEBODY
SCLC-P
R
chr1: 41981788-
N_Shore







41982043


cg04625873
chr11: 118754530
CXCR5.TSS200
SCLC-P
F


cg05244974
chr17: 8798734
PIK3R5.GENEBODY
SCLC-P
R


cg05680240
chr6: 31765195
LSM2.UTR3
SCLC-P
R
chr6: 31763240-
S_Shore







31763905


cg05766510
chr7: 157454062
PTPRN2.GENEBODY
SCLC-P
R
chr7: 157453774-
Island







157454208


cg05845757
chr1: 36039885
TFAP2E.GENEBODY
SCLC-P
F
chr1: 36038927-
Island







36040051


cg05913474
chr8: 144815204
FAM83H.UTR5
SCLC-P
R
chr8: 144815203-
Island







144816518


cg05926586
chr15: 74592786
CCDC33.GENEBODY
SCLC-P
R


cg06788504
chr6: 32974517
HLA-DOA.UTR3
SCLC-P
F
chr6: 32975684-
N_Shore







32975926


cg06860422
chr16: 788079
NARFL.GENEBODY
SCLC-P
F
chr16: 787070-787327
S_Shore


cg07159802
chr1: 247921568
OR1C1.EXON1
SCLC-P
F


cg07344019
chr15: 69337685
MIR548H4.GENEBODY
SCLC-P
F


cg07470396
chr19: 54697539
TSEN34.UTR3
SCLC-P
F
chr19: 54693034-
S_Shelf







54695497


cg08192337
chr12: 124982002
NCOR2.UTR5
SCLC-P
F


cg08210506
chr14: 81456824
TSHR.GENEBODY
SCLC-P
F


cg08797864
chr3: 185531258
IGF2BP2.GENEBODY
SCLC-P
R


cg08822746
chr22: 31321152
C22orf27.GENEBODY
SCLC-P
R
chr22: 31318228-
S_Shelf







31318489


cg08856378
chr17: 560590
VPS53.GENEBODY
SCLC-P
R


cg09274040
chr10: 134994455
KNDC1.GENEBODY
SCLC-P
R
chr10: 134996318-
N_Shore







134996548


cg09506037
chr2: 134180560
NCKAP5.GENEBODY
SCLC-P
F


cg09900440
chr6: 33033312
HLA-DPA1.UTR3
SCLC-P
R


cg09910067
chr7: 157357758
PTPRN2.GENEBODY
SCLC-P
R
chr7: 157361512-
N_Shelf







157361805


cg10572969
chr11: 13690188
FAR1.TSS200
SCLC-P
F
chr11: 13689588-
Island







13690724


cg11156873
chr5: 1491579
LPCAT1.GENEBODY
SCLC-P
R
chr5: 1489799-1490071
S_Shore


cg11514462
chr11: 121001293
TECTA.GENEBODY
SCLC-P
F
chr11: 120998386-
S_Shelf







120998886


cg12192566
chr5: 140011377
CD14.UTR3
SCLC-P
F
chr5: 140011482-
N_Shore







140012739


cg13337413
chr17: 10728324
PIRT.UTR3
SCLC-P
F


cg13607138
chr20: 33539306
GSS.GENEBODY
SCLC-P
R
chr20: 33543082-
N_Shelf







33543846


cg14150071
chr1: 33545982
ADC.TSS1500
SCLC-P
F
chr1: 33546524-
N_Shore







33547243


cg14286660
chr7: 1050071
C7orf50.GENEBODY
SCLC-P
F
chr7: 1048921-1049124
S_Shore


cg14826031
chr11: 75376361
MAP6.GENEBODY
SCLC-P
F
chr11: 75378416-
N_Shelf







75379882


cg15005255
chr19: 18368728
KIAA1683.GENEBODY
SCLC-P
F
chr19: 18368482-
Island







18368911


cg15344504
chr3: 31677078
STT3B.GENEBODY
SCLC-P
F


cg17045790
chr12: 6128269
VWF.GENEBODY
SCLC-P
F


cg17771737
chr19: 20150505
ZNF682.TSS1500
SCLC-P
R
chr19: 20149855-
S_Shore







20150175


cg18554789
chr7: 139432178
HIPK2.GENEBODY
SCLC-P
F


cg18559249
chr17: 37760173
NEUROD2.UTR3
SCLC-P
F
chr17: 37761691-
N_Shore







37763551


cg19402335
chr1: 159410002
OR10J1.EXON1
SCLC-P
R


cg20484653
chr1: 204955033
NFASC.GENEBODY
SCLC-P
F
chr1: 204950982-
S_Shelf







204951210


cg21045306
chr12: 57637925
STAC3.GENEBODY
SCLC-P
R
chr12: 57636557-
S_Shore







57637673


cg21378690
chrX: 71694534
HDAC8.UTR3
SCLC-P
F


cg21745287
chr12: 123464511
ARL6IP4.TSS1500
SCLC-P
R
chr12: 123464820-
N_Shore







123465972


cg22931292
chr11: 17765568
KCNC1.GENEBODY
SCLC-P
R


cg24627621
chr6: 42109176
C6orf132.GENEBODY
SCLC-P
R
chr6: 42109904-
N_Shore







42110361


cg24931632
chr1: 47899667
MGC12982.GENEBODY
SCLC-P
F
chr1: 47899661-
Island







47900385


cg25199552
chr1: 23350054
KDM1A.GENEBODY
SCLC-P
R
chr1: 23345814-
S_Shelf







23346677


cg25647583
chr15: 91427184
FES.TSS1500
SCLC-P
F
chr15: 91427540-
N_Shore







91427905


cg25716623
chr15: 89921845
LOC254559.GENEBODY
SCLC-P
F
chr15: 89920793-
Island







89922768


cg26009944
chr1: 52210504
OSBPL9.UTR5
SCLC-P
F


cg26355228
chr2: 3260869
TSSC1.GENEBODY
SCLC-P
F


cg26406292
chr7: 75292248
HIP1.GENEBODY
SCLC-P
F


cg27113326
chr7: 157454068
PTPRN2.GENEBODY
SCLC-P
R
chr7: 157453774-
Island







157454208


cg00108992
chr16: 12192325
SNX29.GENEBODY
SCLC-P
R


cg00168967
chr8: 62505560
ASPH.GENEBODY
SCLC-P
R


cg00256675
chr4: 802962
CPLX1.GENEBODY
SCLC-P
R
chr4: 798538-798984
S_Shelf


cg00572387
chr20: 1472914
SIRPB2.TSS1500
SCLC-P
R


cg00582579
chr8: 135533786
ZFAT.GENEBODY
SCLC-P
R


cg00629585
chr9: 135853992
GFI1B.TSS200
SCLC-P
R


cg00869989
chr19: 2774197
SGTA.UTR5
SCLC-P
F
chr19: 2774196-2774550
Island


cg00957480
chr17: 10728755
PIRT.GENEBODY
SCLC-P
R


cg01120761
chr12: 7903170
CLEC4C.TSS1500
SCLC-P
R


cg01953456
chr3: 183817976
HTR3E.UTR5
SCLC-P
R


cg02264238
chr3: 51426377
MANF.GENEBODY
SCLC-P
R
chr3: 51428412-
N_Shelf







51429625


cg02308914
chr3: 129290549
PLXND1.GENEBODY
SCLC-P
R


cg02590486
chr12: 499376
KDM5A.TSS1500
SCLC-P
R
chr12: 498098-498920
S_Shore


cg02882755
chr6: 34100963
GRM4.EXON1
SCLC-P
R


cg02915544
chr11: 89392829
FOLH1B.UTR5
SCLC-P
R


cg03231860
chr11: 128893940
RICS.EXON1
SCLC-P
F


cg03243669
chr7: 1931776
MAD1L1.GENEBODY
SCLC-P
F


cg03465847
chrX: 40594937
MED14.TSS200
SCLC-P
F
chrX: 40594515-
Island







40595457


cg03766174
chr16: 81547907
CMIP.GENEBODY
SCLC-P
F


cg04428805
chr17: 65239522
HELZ.UTR5
SCLC-P
R
chr17: 65240725-
N_Shore







65242498


cg04756594
chr16: 24857601
SLC5A11.EXON1
SCLC-P
R


cg05647891
chr4: 153346037
FBXW7.UTR5
SCLC-P
F


cg05794927
chr1: 248059252
OR2W3.EXON1
SCLC-P
F


cg05938958
chr1: 248224887
OR2L3.EXON1
SCLC-P
F


cg06222979
chr18: 14543469
POTEC.UTR5
SCLC-P
F


cg06531741
chr11: 113775450
HTR3B.TSS200
SCLC-P
F


cg06969933
chr16: 88099740
BANP.GENEBODY
SCLC-P
F
chr16: 88101473-
N_Shore







88101911


cg07474672
chr6: 90142171
ANKRD6.TSS1500
SCLC-P
F
chr6: 90142751-
N_Shore







90143635


cg07825294
chr19: 1415757
DAZAP1.GENEBODY
SCLC-P
R
chr19: 1419751-1420405
N_Shelf


cg07915189
chr19: 7688621
XAB2.GENEBODY
SCLC-P
R
chr19: 7688620-7688832
Island


cg08468599
chr1: 2182126
SKI.GENEBODY
SCLC-P
F


cg08813944
chr17: 71258589
CPSF4L.TSS1500
SCLC-P
F


cg08917933
chr1: 19615303
AKR7A3.TSS200
SCLC-P
R
chr1: 19614998-
Island







19615660


cg08927102
chr1: 1050110
C1orf159.UTR5
SCLC-P
F
chr1: 1050515-1050830
N_Shore


cg09419176
chr7: 157670705
PTPRN2.GENEBODY
SCLC-P
R
chr7: 157669879-
S_Shore







157670095


cg09445097
chr9: 130186736
ZNF79.UTR5
SCLC-P
R
chr9: 130186276-
Island







130187160


cg09867656
chr1: 76550508
ST6GALNAC3.GENEBODY
SCLC-P
R


cg09934892
chr16: 3559551
CLUAP1.GENEBODY
SCLC-P
F


cg10100117
chr1: 179843111
TOR1AIP2.UTR5
SCLC-P
R
chr1: 179846879-
N_Shelf







179847106


cg10329874
chr11: 66621442
PC.GENEBODY
SCLC-P
R
chr11: 66623620-
N_Shelf







66626614


cg10409230
chr17: 40318360
KCNH4.GENEBODY
SCLC-P
F


cg10487770
chr5: 57879443
RAB3C.GENEBODY
SCLC-P
R
chr5: 57878725-
S_Shore







57879177


cg10719970
chr6: 41529932
FOXP4.UTR5
SCLC-P
R
chr6: 41528266-
S_Shore







41528900


cg11375616
chr21: 47287017
PCBP3.GENEBODY
SCLC-P
R
chr21: 47287012-
Island







47287426


cg11397606
chr1: 67151389
SGIP1.GENEBODY
SCLC-P
R


cg11661493
chr17: 74423978
UBE2O.GENEBODY
SCLC-P
F


cg11866943
chr3: 52529351
STAB1.TSS200
SCLC-P
F


cg12426652
chr21: 37915056
CLDN14.TSS200
SCLC-P
F


cg12991341
chr8: 109800287
TMEM74.TSS1500
SCLC-P
F
chr8: 109799429-
S_Shore







109799847


cg13372513
chr7: 158177056
PTPRN2.GENEBODY
SCLC-P
F


cg13534791
chr9: 35042344
C9orf131.EXON1
SCLC-P
F


cg13995599
chr13: 113426270
ATP11A.GENEBODY
SCLC-P
R
chr13: 113424898-
S_Shore







113425105


cg14274019
chr9: 134184504
PPAPDC3.UTR3
SCLC-P
R
chr9: 134183330-
S_Shore







134183613


cg14879948
chr5: 1394576
SLC6A3.UTR3
SCLC-P
F


cg15147833
chr1: 247921672
OR1C1.EXON1
SCLC-P
R


cg15617023
chr13: 40113248
LHFP.GENEBODY
SCLC-P
R


cg15871371
chr3: 71274624
FOXP1.UTR5
SCLC-P
F


cg15871766
chr12: 52365222
ACVR1B.GENEBODY
SCLC-P
F


cg16748694
chr10: 126754386
CTBP2.UTR5
SCLC-P
R


cg16895672
chr10: 34470745
PARD3.GENEBODY
SCLC-P
R


cg16983282
chr17: 9871831
GAS7.GENEBODY
SCLC-P
R


cg17013166
chr22: 30961151
GAL3ST1.TSS1500
SCLC-P
R


cg17135722
chr20: 17295815
PCSK2.GENEBODY
SCLC-P
R
chr20: 17296125-
N_Shore







17296531


cg17179826
chr1: 204946032
NFASC.UTR3
SCLC-P
R


cg17707347
chr1: 234614967
TARBP1.TSS200
SCLC-P
F
chr1: 234613936-
Island







234614972


cg17810765
chr2: 242127836
ANO7.TSS200
SCLC-P
R


cg17912283
chr17: 72350487
KIF19.GENEBODY
SCLC-P
F
chr17: 72350346-
Island







72350711


cg18502477
chr11: 57946199
OR9Q1.UTR5
SCLC-P
F


cg18812946
chrX: 153140985
L1CAM.GENEBODY
SCLC-P
F


cg18861762
chr2: 242127852
ANO7.TSS200
SCLC-P
F


cg19148404
chr3: 14443444
SLC6A6.TSS1500
SCLC-P
F
chr3: 14443629-
N_Shore







14444577


cg19273683
chr1: 21656047
ECE1.GENEBODY
SCLC-P
R


cg19325793
chr6: 33082165
HLA-DPB2.GENEBODY
SCLC-P
F
chr6: 33084740-
N_Shelf







33084995


cg19393755
chr17: 71258101
CPSF4L.TSS200
SCLC-P
F


cg19405329
chr15: 49440632
COPS2.GENEBODY
SCLC-P
F


cg19547192
chr7: 158059976
PTPRN2.GENEBODY
SCLC-P
R
chr7: 158060894-
N_Shore







158061100


cg19606462
chr5: 7827964
ADCY2.UTR3
SCLC-P
R


cg20682981
chr17: 1962627
HIC1.UTR3
SCLC-P
F
chr17: 1952919-1962328
S_Shore


cg21029612
chr15: 89921258
LOC254559.TSS200
SCLC-P
R
chr15: 89920793-
Island







89922768


cg21552242
chr3: 157814326
SHOX2.UTR3
SCLC-P
R
chr3: 157815581-
N_Shore







157816095


cg21703606
chr12: 54427884
HOXC4.UTR5
SCLC-P
R
chr12: 54427025-
Island







54428709


cg21900589
chr8: 22866294
RHOBTB2.GENEBODY
SCLC-P
F
chr8: 22864324-
S_Shore







22864588


cg22791545
chr17: 1924319
RTN4RL1.GENEBODY
SCLC-P
R
chr17: 1927051-1929408
N_Shelf


cg22821554
chr7: 99383155
CYP3A4.TSS1500
SCLC-P
F


cg23055499
chr12: 51847363
SLC4A8.GENEBODY
SCLC-P
F


cg23172995
chr5: 150486801
ANXA6.GENEBODY
SCLC-P
R


cg23714707
chr17: 17418691
PEMT.GENEBODY
SCLC-P
R


cg23833461
chr17: 9929528
GAS7.EXON1
SCLC-P
R


cg24603972
chr10: 61434211
SLC16A9.GENEBODY
SCLC-P
F


cg25129480
chr1: 185126704
C1orf25.TSS1500
SCLC-P
F
chr1: 185125850-
Island







185126705


cg25312122
chr1: 160184732
PEA15.UTR3
SCLC-P
R


cg25425390
chr12: 42763958
PPHLN1.GENEBODY
SCLC-P
R


cg25985583
chr7: 26404716
SNX10.GENEBODY
SCLC-P
R


cg26306056
chr6: 32972989
HLA-DOA.UTR3
SCLC-P
R
chr6: 32975684-
N_Shelf







32975926


cg26353877
chr1: 159557886
APCS.GENEBODY
SCLC-P
R


cg26558420
chr20: 30331315
TPX2.UTR5
SCLC-P
R
chr20: 30326913-
S_Shelf







30327430


cg26577231
chr19: 18368873
KIAA1683.GENEBODY
SCLC-P
F
chr19: 18368482-
Island







18368911


cg26942930
chr7: 147804524
CNTNAP2.GENEBODY
SCLC-P
R


cg27150178
chr19: 1456337
APC2.GENEBODY
SCLC-P
F
chr19: 1456077-1456347
Island


cg01173794
chr19: 36131225
ETV2.TSS1500
SCLC-P
F
chr19: 36134153-
N_Shelf







36135781


cg24774182
chr15: 22017473
CXADRP2.TSS1500
SCLC-P
F


cg27541374
chr17: 58042493
RNFT1.TSS1500
SCLC-P
R
chr17: 58041846-
S_Shore







58042463


cg00401265
chrX: 78003113
LPAR4.TSS200
SCLC-P
F


cg00435063
chr7: 157454207
PTPRN2.GENEBODY
SCLC-P
F
chr7: 157453774-
Island







157454208


cg00515756
chr11: 61464876
DAGLA.UTR5
SCLC-P
R


cg00653387
chr7: 137028535
PTN.UTR5
SCLC-P
F


cg00808053
chr12: 6125746
VWF.GENEBODY
SCLC-P
F


cg00808511
chr16: 52495237
TOX3.GENEBODY
SCLC-P
R


cg01132064
chr11: 46382562
DGKZ.GENEBODY
SCLC-P
F


cg01403030
chr9: 19026479
FAM154A.GENEBODY
SCLC-P
R
chr9: 19027850-
N_Shore







19028064


cg01507200
chr1: 247877066
OR6F1.TSS1500
SCLC-P
R


cg01708636
chr4: 166301085
CPE.GENEBODY
SCLC-P
R
chr4: 166299975-
S_Shore







166300668


cg02077068
chr16: 19872240
GPRC5B.GENEBODY
SCLC-P
R


cg03081691
chr1: 226188006
C1orf55.TSS1500
SCLC-P
F
chr1: 226186803-
S_Shore







226187336


cg03306486
chr19: 1467952
APC2.GENEBODY
SCLC-P
F
chr19: 1465206-1471241
Island


cg04383012
chr2: 231921692
PSMD1.EXON1
SCLC-P
R
chr2: 231921413-
Island







231921972


cg04655481
chr9: 125796809
GPR21.TSS200
SCLC-P
F


cg04665588
chr17: 14243776
HS3ST3B1.GENEBODY
SCLC-P
F


cg04804648
chr17: 72348295
KIF19.GENEBODY
SCLC-P
F
chr17: 72347924-
Island







72348322


cg04809274
chr6: 32977254
HLA-DOA.EXON1
SCLC-P
F
chr6: 32975684-
S_Shore







32975926


cg04962134
chr11: 55653310
SPRYD5.GENEBODY
SCLC-P
R


cg05221455
chr11: 829616
EFCAB4A.GENEBODY
SCLC-P
F
chr11: 829284-833558
Island


cg05720937
chr2: 98280362
ACTR1B.EXON1
SCLC-P
R
chr2: 98280063-
Island







98280871


cg06517181
chr10: 134994252
KNDC1.GENEBODY
SCLC-P
F
chr10: 134993121-
S_Shore







134993324


cg06572563
chr19: 1132966
SBNO2.GENEBODY
SCLC-P
R


cg07100542
chr1: 17402079
PADI2.GENEBODY
SCLC-P
R


cg07436694
chr16: 21638444
METTL9.GENEBODY
SCLC-P
R


cg07586799
chr3: 195591722
TNK2.GENEBODY
SCLC-P
R
chr3: 195594836-
N_Shelf







195595494


cg07870237
chr5: 131348431
ACSL6.TSS1500
SCLC-P
F
chr5: 131346892-
S_Shore







131347776


cg08984900
chr17: 34430281
CCL4.TSS1500
SCLC-P
R


cg09524686
chr11: 829182
EFCAB4A.GENEBODY
SCLC-P
F
chr11: 829284-833558
N_Shore


cg09565226
chr16: 84759648
USP10.GENEBODY
SCLC-P
R


cg10256976
chr11: 20078682
NAV2.GENEBODY
SCLC-P
F


cg10327976
chr15: 42843303
HAUS2.GENEBODY
SCLC-P
R
chr15: 42840462-
S_Shelf







42841116


cg10341513
chr22: 51041242
MAPK8IP2.TSS1500
SCLC-P
R
chr22: 51042293-
N_Shore







51043422


cg10521450
chr10: 105439280
SH3PXD2A.GENEBODY
SCLC-P
R


cg10959048
chr3: 93694020
PROS1.TSS1500
SCLC-P
R
chr3: 93692554-
S_Shore







93692783


cg11049863
chr17: 80832470
TBCD.GENEBODY
SCLC-P
F
chr17: 80829533-
S_Shelf







80829871


cg11150074
chr1: 200863559
C1orf106.TSS1500
SCLC-P
R
chr1: 200860076-
S_Shelf







200860576


cg11321144
chr4: 151178020
DCLK2.UTR3
SCLC-P
F
chr4: 151177347-
S_Shore







151177559


cg11521965
chr7: 137028604
PTN.TSS200
SCLC-P
F


cg11581706
chr7: 82072141
CACNA2D1.GENEBODY
SCLC-P
F
chr7: 82072021-
Island







82073520


cg12196847
chr14: 81426577
TSHR.GENEBODY
SCLC-P
R


cg12617146
chr10: 97101836
SORBS1.GENEBODY
SCLC-P
R


cg13617795
chr7: 105137683
PUS7.GENEBODY
SCLC-P
F


cg13698125
chr9: 140391480
PNPLA7.GENEBODY
SCLC-P
R
chr9: 140389453-
S_Shore







140389751


cg13921245
chr6: 33053791
HLA-DPB1.GENEBODY
SCLC-P
F


cg14022090
chr11: 34642303
EHF.TSS1500
SCLC-P
F


cg14147151
chr9: 138948000
NACC2.UTR5
SCLC-P
R
chr9: 138941470-
S_Shelf







138944021


cg14322298
chr6: 10585683
GCNT2.GENEBODY
SCLC-P
F


cg14402562
chr11: 8945810
C11orf16.GENEBODY
SCLC-P
R


cg15287806
chr10: 237794
ZMYND11.GENEBODY
SCLC-P
R


cg15332132
chr20: 62183964
C20orf195.TSS1500
SCLC-P
R
chr20: 62185073-
N_Shore







62185572


cg15367000
chr2: 239017149
ESPNL.GENEBODY
SCLC-P
F


cg15463309
chr8: 141598157
EIF2C2.GENEBODY
SCLC-P
F


cg16182685
chr2: 3260980
TSSC1.GENEBODY
SCLC-P
F


cg16280667
chr11: 118754593
CXCR5.UTR5
SCLC-P
F


cg16477417
chr17: 73342168
GRB2.GENEBODY
SCLC-P
F


cg16711332
chr1: 6531727
PLEKHG5.GENEBODY
SCLC-P
F
chr1: 6530536-6531814
Island


cg16791781
chr11: 986922
AP2A2.GENEBODY
SCLC-P
R


cg17777731
chr6: 32976131
HLA-DOA.GENEBODY
SCLC-P
R
chr6: 32975684-
S_Shore







32975926


cg17947172
chr1: 204966197
NFASC.GENEBODY
SCLC-P
R


cg18702239
chrX: 69663606
DLG3.TSS1500
SCLC-P
F
chrX: 69665102-
N_Shore







69665355


cg18715243
chr8: 37658755
GPR124.GENEBODY
SCLC-P
R
chr8: 37654048-
S_Shelf







37656100


cg18969798
chr4: 151157003
DCLK2.GENEBODY
SCLC-P
R


cg19185706
chr10: 88475771
LDB3.GENEBODY
SCLC-P
F
chr10: 88470905-
S_Shelf







88471934


cg19409156
chr15: 48413040
SLC24A5.TSS200
SCLC-P
R


cg19427746
chr17: 4889932
CAMTA2.UTR5
SCLC-P
R
chr17: 4890282-4890991
N_Shore


cg20100408
chr6: 33050888
HLA-DPB1.GENEBODY
SCLC-P
F
chr6: 33048416-
S_Shelf







33048814


cg20541233
chr21: 18938039
CXADR.UTR3
SCLC-P
R


cg20907136
chr6: 33041221
HLA-DPA1.GENEBODY
SCLC-P
F


cg20938170
chr11: 75428910
MOGAT2.TSS200
SCLC-P
R


cg21748244
chr5: 169713179
LCP2.GENEBODY
SCLC-P
F


cg21776674
chr1: 6160143
KCNAB2.UTR3
SCLC-P
F


cg22007216
chr4: 155312410
DCHS2.GENEBODY
SCLC-P
R


cg22381352
chr1: 146742008
CHD1L.GENEBODY
SCLC-P
R


cg22442557
chr17: 79011352
BAIAP2.GENEBODY
SCLC-P
R
chr17: 79008929-
S_Shore







79009762


cg22858170
chr5: 39204386
FYB.UTR5
SCLC-P
R


cg23095615
chr6: 146136563
FBXO30.TSS1500
SCLC-P
F
chr6: 146136325-
Island







146136564


cg23326197
chr7: 99382370
CYP3A4.TSS1500
SCLC-P
F


cg23645261
chr19: 30940563
ZNF536.GENEBODY
SCLC-P
F
chr19: 30941853-
N_Shore







30942181


cg23676767
chr1: 226918736
ITPKB.GENEBODY
SCLC-P
R


cg23699947
chr12: 27167077
TM7SF3.EXON1
SCLC-P
F
chr12: 27166996-
Island







27167464


cg23777946
chr18: 24125409
KCTD1.UTR5
SCLC-P
R
chr18: 24126780-
N_Shore







24131138


cg23998119
chr14: 77600217
ZDHHC22.GENEBODY
SCLC-P
R


cg24214000
chr22: 50282386
ZBED4.UTR3
SCLC-P
F
chr22: 50279568-
S_Shelf







50280376


cg24396358
chr6: 32977400
HLA-DOA.TSS200
SCLC-P
F
chr6: 32975684-
S_Shore







32975926


cg24436022
chr22: 45691661
UPK3A.UTR3
SCLC-P
F


cg24625894
chr8: 145638202
SLC39A4.GENEBODY
SCLC-P
R
chr8: 145637965-
Island







145639182


cg24678581
chr5: 170882542
FGF18.GENEBODY
SCLC-P
R
chr5: 170883600-
N_Shore







170883836


cg24938100
chr6: 33091407
HLA-DPB2.GENEBODY
SCLC-P
R


cg25693265
chr7: 6517860
KDELR2.GENEBODY
SCLC-P
R


cg26345142
chr12: 109305794
SVOP.UTR3
SCLC-P
F


cg26490671
chr7: 157670732
PTPRN2.GENEBODY
SCLC-P
R
chr7: 157669879-
S_Shore







157670095


cg26692016
chr12: 7817844
APOBEC1.GENEBODY
SCLC-P
R


cg26871279
chr11: 2423559
TSSC4.UTR5
SCLC-P
R
chr11: 2421040-2422474
S_Shore


cg27504782
chr7: 94284258
SGCE.GENEBODY
SCLC-P
R
chr7: 94284858-
N_Shore







94286527


cg00731886
chr4: 1363008
KIAA1530.GENEBODY
SCLC-P
F
chr4: 1364146-1364349
N_Shore


cg00896220
chr17: 34639327
CCL4L1.TSS1500
SCLC-P
R


cg01443488
chr1: 159557514
APCS.TSS200
SCLC-P
F


cg01924561
chr1: 43416103
SLC2A1.GENEBODY
SCLC-P
F


cg04810997
chr7: 143140674
TAS2R60.EXON1
SCLC-P
R


cg05677694
chr6: 33052797
HLA-DPB1.GENEBODY
SCLC-P
F
chr6: 33048416-
S_Shelf







33048814


cg11070176
chr11: 70489806
SHANK2.GENEBODY
SCLC-P
F


cg11941526
chrX: 38660299
MID1IP1.TSS1500
SCLC-P
F
chrX: 38662906-
N_Shelf







38664764


cg14517144
chr10: 70098420
HNRNPH3.GENEBODY
SCLC-P
F


cg14684709
chr13: 100547249
CLYBL.UTR3
SCLC-P
F
chr13: 100547172-
Island







100547431


cg16537306
chr17: 9850268
GAS7.GENEBODY
SCLC-P
R


cg17753661
chr1: 26441637
PDIK1L.GENEBODY
SCLC-P
F
chr1: 26437319-
S_Shelf







26438917


cg23710594
chr1: 33841330
PHC2.TSS200
SCLC-P
R


cg00935894
chr8: 110705093
GOLSYN.TSS1500
SCLC-P
R
chr8: 110703409-
S_Shore







110703897


cg01083652
chr15: 71629208
THSD4.GENEBODY
SCLC-P
R


cg02075590
chr4: 125607552
ANKRD50.UTR5
SCLC-P
R


cg02169973
chr19: 50983986
C19orf63.GENEBODY
SCLC-P
F
chr19: 50983853-
Island







50984075


cg02220617
chr14: 102312533
PPP2R5C.GENEBODY
SCLC-P
R


cg02555215
chr12: 113497560
DTX1.GENEBODY
SCLC-P
R
chr12: 113494389-
S_Shelf







113495534


cg02963493
chr19: 11568915
ELAVL3.GENEBODY
SCLC-P
R
chr19: 11565384-
S_Shelf







11565711


cg03252568
chr17: 41727259
MEOX1.GENEBODY
SCLC-P
F
chr17: 41723219-
S_Shelf







41723826


cg01862650
chr5: 143619194
KCTD16.GENEBODY
SCLC-P
R


cg01828813
chr6: 33132705
COL11A2.GENEBODY
SCLC-P
R
chr6: 33129291-
S_Shelf







33129718


cg19887293
chr6: 33132693
COL11A2.GENEBODY
SCLC-P
R
chr6: 33129291-
S_Shelf







33129718


cg25736198
chr12: 72345225
TPH2.GENEBODY
SCLC-P
R


cg01159294
chr5: 143763289
KCTD16.GENEBODY
SCLC-P
F


cg23009046
chr11: 119600595
PVRL1.TSS1500
SCLC-P
R
chr11: 119598382-
S_Shore







119600157


cg26548251
chr7: 147591462
MIR548F3.TSS1500
SCLC-P
F


cg00177243
chr10: 18434068
CACNB2.GENEBODY
SCLC-P
F
chr10: 18429125-
S_Shelf







18430234


cg03050127
chr17: 59413660
BCAS3.GENEBODY
SCLC-P
R


cg26357587
chr11: 120110882
POU2F3.TSS200
SCLC-P
R
chr11: 120110497-
S_Shore







120110719


cg02965092
chr12: 72347052
TPH2.GENEBODY
SCLC-P
F


cg07961632
chr1: 27668421
SYTL1.TSS200
SCLC-P
R


cg10380643
chr1: 1356764
LOC441869.TSS200
SCLC-P
R
chr1: 1355159-1356000
S_Shore


cg17790159
chr6: 33133083
COL11A2.GENEBODY
SCLC-P
R
chr6: 33129291-
S_Shelf







33129718


cg14154859
chr1: 220702826
MARK1.GENEBODY
SCLC-P
F
chr1: 220701507-
S_Shore







220702348


cg10120778
chr7: 42018795
GLI3.GENEBODY
SCLC-P
F


cg15700587
chr7: 147065665
MIR54814.GENEBODY
SCLC-P
R


cg00333034
chr3: 183948058
VWA5B2.TSS1500
SCLC-I
F
chr3: 183947040-
Island







183948801


cg00789347
chr16: 2039030
SYNGR3.TSS1500
SCLC-I
F
chr16: 2040034-2040628
N_Shore


cg01507577
chr7: 146484609
CNTNAP2.GENEBODY
SCLC-I
R


cg02379560
chr4: 40859280
APBB2.GENEBODY
SCLC-I
F
chr4: 40858884-
S_Shore







40859162


cg04917391
chr4: 40859259
APBB2.GENEBODY
SCLC-I
F
chr4: 40858884-
S_Shore







40859162


cg05894734
chr4: 40859249
APBB2.GENEBODY
SCLC-I
F
chr4: 40858884-
S_Shore







40859162


cg06485940
chr4: 40859293
APBB2.GENEBODY
SCLC-I
F
chr4: 40858884-
S_Shore







40859162


cg07035001
chr7: 146321053
CNTNAP2.GENEBODY
SCLC-I
F


cg12455762
chr4: 40859095
APBB2.GENEBODY
SCLC-I
F
chr4: 40858884-
Island







40859162


cg14230238
chr19: 6066871
RFX2.UTR5
SCLC-I
R


cg14248352
chr7: 146820536
CNTNAP2.GENEBODY
SCLC-I
R


cg14652038
chr2: 222343519
EPHA4.GENEBODY
SCLC-I
R


cg16364495
chr4: 40859251
APBB2.GENEBODY
SCLC-I
F
chr4: 40858884-
S_Shore







40859162


cg22519702
chr5: 147204189
SPINK1.UTR3
SCLC-I
R


cg23735712
chr4: 40858984
APBB2.GENEBODY
SCLC-I
F
chr4: 40858884-
Island







40859162


cg23889772
chr19: 10077324
COL5A3.GENEBODY
SCLC-I
F
chr19: 10077031-
Island







10077444


cg25649655
chr8: 145692504
CYHR1.TSS1500
SCLC-I
F
chr8: 145690605-
Island







145692505


cg26244738
chr4: 40859344
APBB2.GENEBODY
SCLC-I
R
chr4: 40858884-
S_Shore







40859162


cg26470314
chr16: 2039411
SYNGR3.TSS1500
SCLC-I
R
chr16: 2040034-2040628
N_Shore


cg01657995
chr6: 31804883
C6orf48.UTR5
SCLC-I
F
chr6: 31802598-
S_Shelf







31802823


cg02269097
chr12: 49487944
DHH.GENEBODY
SCLC-I
R
chr12: 49487963-
N_Shore







49488202


cg03392565
chr1: 212464932
PPP2R5A.GENEBODY
SCLC-I
R


cg03957440
chr1: 214209324
PROX1.UTR3
SCLC-I
R


cg09050775
chr12: 46762708
SLC38A2.GENEBODY
SCLC-I
R
chr12: 46765134-
N_Shelf







46766633


cg11526866
chr1: 20813614
CAMK2N1.TSS1500
SCLC-I
F
chr1: 20810462-
S_Shore







20813511


cg13109300
chr12: 49488587
DHH.UTR5
SCLC-I
F
chr12: 49487963-
S_Shore







49488202


cg16151451
chr11: 849153
TSPAN4.UTR5
SCLC-I
F
chr11: 849087-850982
Island


cg16405211
chr7: 146897691
CNTNAP2.GENEBODY
SCLC-I
R


cg17490790
chr19: 10125043
RDH8.GENEBODY
SCLC-I
R
chr19: 10120750-
S_Shelf







10121231


cg18804920
chr7: 146572638
CNTNAP2.GENEBODY
SCLC-I
R


cg19075717
chr17: 48670940
CACNA1G.GENEBODY
SCLC-I
R


cg24127874
chr2: 239149859
HES6.TSS1500
SCLC-I
F
chr2: 239147592-
Island







239149900


cg04303901
chr12: 97886312
RMST.GENEBODY
SCLC-I
F


cg04695027
chr11: 65793986
CATSPER1.EXON1
SCLC-I
R
chr11: 65789909-
S_Shelf







65790168


cg04865716
chr19: 2290843
LINGO3.GENEBODY
SCLC-I
R
chr19: 2289895-2291904
Island


cg05582979
chr4: 10686610
CLNK.TSS1500
SCLC-I
F


cg06093379
chr17: 44896080
WNT3.UTR5
SCLC-I
R
chr17: 44895800-
Island







44897025


cg08384314
chr6: 30711680
IER3.UTR3
SCLC-I
R
chr6: 30710307-
Island







30712440


cg09267188
chr8: 97340225
PTDSS1.GENEBODY
SCLC-I
R


cg12724192
chr4: 82392157
RASGEF1B.UTR5
SCLC-I
R
chr4: 82392610-
N_Shore







82393426


cg13067221
chr14: 23449582
JUB.GENEBODY
SCLC-I
F
chr14: 23449886-
N_Shore







23452174


cg16406078
chr20: 825634
FAM110A.GENEBODY
SCLC-I
F
chr20: 825267-826276
Island


cg17971747
chr15: 45410236
DUOXA1.GENEBODY
SCLC-I
F
chr15: 45408573-
S_Shore







45409528


cg22942704
chr1: 20813574
CAMK2N1.TSS1500
SCLC-I
R
chr1: 20810462-
S_Shore







20813511


cg25151498
chr3: 185815992
ETV5.GENEBODY
SCLC-I
F


cg25564319
chr3: 63558416
SYNPR.GENEBODY
SCLC-I
F


cg27190967
chr16: 2039391
SYNGR3.TSS1500
SCLC-I
F
chr16: 2040034-2040628
N_Shore


cg01920182
chr12: 23738340
SOX5.TSS1500
SCLC-I
R


cg03595580
chr7: 97880848
TECPR1.UTR5
SCLC-I
F
chr7: 97881132-
N_Shore







97881906


cg04993130
chr11: 726759
EPS8L2.GENEBODY
SCLC-I
R
chr11: 725596-726870
Island


cg06736134
chr5: 147040725
JAKMIP2.GENEBODY
SCLC-I
R


cg09248054
chr1: 969257
AGRN.GENEBODY
SCLC-I
F
chr1: 967966-970238
Island


cg11565786
chr5: 31944970
PDZD2.GENEBODY
SCLC-I
R


cg16769791
chr8: 85178030
RALYL.UTR5
SCLC-I
R


cg19741167
chr2: 86263270
POLR1A.GENEBODY
SCLC-I
R


cg25225073
chr14: 90528983
KCNK13.GENEBODY
SCLC-I
F
chr14: 90526696-
S_Shore







90528951


cg26683639
chr6: 30653755
KIAA1949.GENEBODY
SCLC-I
F
chr6: 30654392-
N_Shore







30654934


cg07788437
chr19: 1799952
ATP8B3.GENEBODY
SCLC-I
R
chr19: 1799934-1800248
Island


cg11207515
chr7: 146904205
CNTNAP2.GENEBODY
SCLC-I
R


cg11540204
chr1: 60391699
CYP2J2.GENEBODY
SCLC-I
R
chr1: 60392272-
N_Shore







60392583


cg11799006
chr5: 147101975
JAKMIP2.UTR5
SCLC-I
R


cg13369952
chr5: 147024959
JAKMIP2.GENEBODY
SCLC-I
F


cg14074581
chr19: 36232218
TMEM149.UTR5
SCLC-I
F
chr19: 36231186-
Island







36232219


cg25183613
chr3: 111717557
TAGLN3.TSS200
SCLC-I
F


cg00967013
chr13: 24735754
SPATA13.UTR5
SCLC-I
F
chr13: 24734771-
S_Shore







24735538


cg02120463
chr22: 39639003
PDGFB.GENEBODY
SCLC-I
F
chr22: 39638219-
Island







39640966


cg02578321
chr1: 247275872
C1orf229.TSS200
SCLC-I
R
chr1: 247274585-
S_Shore







247275757


cg03415518
chr12: 97885729
RMST.GENEBODY
SCLC-I
R


cg04513006
chr16: 68270252
ESRP2.TSS200
SCLC-I
F
chr16: 68269010-
Island







68272143


cg05825085
chr16: 86379872
LOC732275.TSS1500
SCLC-I
F


cg06185146
chr3: 63428305
SYNPR.GENEBODY
SCLC-I
F


cg08669018
chr4: 82392280
RASGEF1B.UTR5
SCLC-I
R
chr4: 82392610-
N_Shore







82393426


cg09473576
chr1: 20813647
CAMK2N1.TSS1500
SCLC-I
F
chr1: 20810462-
S_Shore







20813511


cg10083593
chr11: 66049855
CNIH2.GENEBODY
SCLC-I
R
chr11: 66049750-
Island







66050229


cg11408784
chr17: 7166293
CLDN7.TSS1500
SCLC-I
F
chr17: 7164285-7166245
S_Shore


cg11876912
chr3: 63602009
SYNPR.UTR3
SCLC-I
F


cg13250388
chr22: 39641078
PDGFB.TSS200
SCLC-I
R
chr22: 39638219-
S_Shore







39640966


cg14615553
chr5: 147093466
JAKMIP2.UTR5
SCLC-I
F


cg15149374
chr3: 19576826
KCNH8.UTR3
SCLC-I
R


cg15225810
chr19: 750790
C19orf21.TSS1500
SCLC-I
F
chr19: 746300-747161
S_Shelf


cg17075538
chr19: 15306892
NOTCH3.GENEBODY
SCLC-I
R
chr19: 15306243-
Island







15307111


cg17410295
chr12: 109729809
FOXN4.GENEBODY
SCLC-I
F
chr12: 109729572-
Island







109729826


cg17475643
chr8: 10261972
MSRA.GENEBODY
SCLC-I
F
chr8: 10261900-
Island







10262222


cg19464419
chr6: 94064439
EPHA7.GENEBODY
SCLC-I
R


cg20391895
chr4: 10686394
CLNK.TSS200
SCLC-I
F


cg24238564
chr11: 65779343
CST6.TSS200
SCLC-I
F
chr11: 65779311-
Island







65779767


cg26939195
chr6: 32077020
TNXB.UTR5
SCLC-I
F


cg00026290
chr4: 10686554
CLNK.TSS200
SCLC-I
F


cg02785561
chr8: 10262221
MSRA.GENEBODY
SCLC-I
F
chr8: 10261900-
Island







10262222


cg04221461
chr1: 243877024
AKT3.GENEBODY
SCLC-I
R


cg05082805
chr7: 146489513
CNTNAP2.GENEBODY
SCLC-I
F


cg09433131
chr8: 73480179
KCNB2.GENEBODY
SCLC-I
F


cg11652360
chr6: 33160120
COL11A2.UTR5
SCLC-I
R
chr6: 33159991-
Island







33160263


cg19311889
chr12: 57483793
NAB2.GENEBODY
SCLC-I
R
chr12: 57480797-
S_Shore







57483116


cg00835193
chr19: 2291780
LINGO3.UTR5
SCLC-I
R
chr19: 2289895-2291904
Island


cg01708411
chr12: 57631839
NDUFA4L2.UTR5
SCLC-I
R
chr12: 57631932-
N_Shore







57634578


cg02958126
chr11: 62370246
EML3.GENEBODY
SCLC-I
F
chr11: 62368454-
Island







62370491


cg02989255
chr6: 32063774
TNXB.GENEBODY
SCLC-I
F
chr6: 32063533-
Island







32065044


cg03525956
chr3: 174720287
NAALADL2.GENEBODY
SCLC-I
F


cg06191495
chr2: 234264163
DGKD.GENEBODY
SCLC-I
R


cg11809958
chr12: 32654929
FGD4.TSS200
SCLC-I
R


cg11845241
chr7: 36960377
MIR1200.TSS1500
SCLC-I
R


cg13179469
chr13: 107185675
EFNB2.GENEBODY
SCLC-I
F
chr13: 107186468-
N_Shore







107189024


cg18349863
chr6: 29912713
HLA-A.GENEBODY
SCLC-I
F
chr6: 29910202-
S_Shore







29911367


cg22138393
chr8: 97340270
PTDSS1.GENEBODY
SCLC-I
F


cg26726230
chr17: 79225857
SLC38A10.GENEBODY
SCLC-I
F


cg26961166
chr8: 73687160
KCNB2.GENEBODY
SCLC-I
F


cg26999775
chr14: 105347803
KIAA0284.GENEBODY
SCLC-I
R
chr14: 105350177-
N_Shelf







105350925


cg00433917
chr19: 7915517
EVI5L.GENEBODY
SCLC-I
F
chr19: 7913751-7913968
S_Shore


cg01422274
chr11: 849088
TSPAN4.UTR5
SCLC-I
R
chr11: 849087-850982
Island


cg02245020
chr7: 143580147
FAM115A.UTR5
SCLC-I
R
chr7: 143582125-
N_Shore







143582610


cg04545963
chr14: 35872393
NFKBIA.GENEBODY
SCLC-I
F
chr14: 35873047-
N_Shore







35873990


cg07384913
chr3: 63637118
SNTN.TSS1500
SCLC-I
F


cg07706352
chr19: 10077245
COL5A3.GENEBODY
SCLC-I
R
chr19: 10077031-
Island







10077444


cg08279008
chr2: 86263224
POLR1A.GENEBODY
SCLC-I
F


cg10144863
chr8: 53235234
ST18.UTR5
SCLC-I
R


cg11743827
chr3: 185080905
MAP3K13.TSS200
SCLC-I
R


cg13720581
chr6: 32077017
TNXB.UTR5
SCLC-I
F


cg15148573
chr7: 103498566
RELN.GENEBODY
SCLC-I
F


cg16078836
chr3: 185081374
MAP3K13.UTR5
SCLC-I
R


cg16226037
chr3: 175338261
NAALADL2.GENEBODY
SCLC-I
R


cg16715129
chr11: 10477821
AMPD3.EXON1
SCLC-I
F


cg19418951
chr3: 185080816
MAP3K13.TSS200
SCLC-I
R


cg24519146
chr6: 33160318
COL11A2.TSS200
SCLC-I
F
chr6: 33160945-
N_Shore







33161337


cg25264265
chr3: 185080997
MAP3K13.EXON1
SCLC-I
R


cg25479682
chr3: 185081403
MAP3K13.UTR5
SCLC-I
R


cg26334804
chr19: 41724208
AXL.TSS1500
SCLC-I
R


cg27287254
chr6: 33160067
COL11A2.UTR5
SCLC-I
F
chr6: 33159991-
Island







33160263


cg27633342
chr15: 52588279
MYO5C.TSS1500
SCLC-I
R
chr15: 52587353-
S_Shore







52588172


cg00037056
chr4: 956607
DGKQ.GENEBODY
SCLC-I
F
chr4: 960505-960836
N_Shelf


cg01484141
chr17: 1624157
WDR81.GENEBODY
SCLC-I
R
chr17: 1627745-1629897
N_Shelf


cg01679081
chr5: 60139131
ELOVL7.UTR5
SCLC-I
F
chr5: 60139359-
N_Shore







60140155


cg01886125
chr2: 110054030
SH3RF3.GENEBODY
SCLC-I
F


cg03508107
chr17: 47654357
NXPH3.GENEBODY
SCLC-I
F
chr17: 47653211-
Island







47654369


cg03676636
chr4: 99064102
C4orf37.GENEBODY
SCLC-I
R
chr4: 99064602-
N_Shore







99064805


cg03850035
chr2: 222367110
EPHA4.GENEBODY
SCLC-I
R


cg04083466
chr6: 25753732
SLC17A4.TSS1500
SCLC-I
F


cg05396397
chr1: 11908164
NPPA.TSS1500
SCLC-I
R


cg07107420
chr7: 8010894
GLCCI1.GENEBODY
SCLC-I
F
chr7: 8008097-8009495
S_Shore


cg10242279
chr4: 10666415
CLNK.GENEBODY
SCLC-I
R


cg12286569
chr19: 18722620
TMEM59L.TSS1500
SCLC-I
R
chr19: 18722358-
Island







18724001


cg13298116
chr11: 62369859
EML3.UTR3
SCLC-I
R
chr11: 62368454-
Island







62370491


cg14848284
chr2: 73143293
EMX1.TSS1500
SCLC-I
R
chr2: 73143055-
Island







73148260


cg16686429
chr19: 46284983
DMPK.GENEBODY
SCLC-I
F
chr19: 46282544-
S_Shore







46283127


cg18164281
chr20: 2797721
LOC100288797.UTR3
SCLC-I
R
chr20: 2801639-2802135
N_Shelf


cg18776945
chr5: 147024842
JAKMIP2.GENEBODY
SCLC-I
R


cg19250002
chr22: 20460068
RIMBP3.EXON1
SCLC-I
F
chr22: 20459267-
Island







20461473


cg19268434
chr6: 32076967
TNXB.UTR5
SCLC-I
F


cg22076422
chr3: 63399168
SYNPR.GENEBODY
SCLC-I
R


cg22168512
chr18: 74695224
MBP.GENEBODY
SCLC-I
F
chr18: 74691262-
S_Shelf







74691466


cg26248155
chr17: 7165849
CLDN7.TSS200
SCLC-I
R
chr17: 7164285-7166245
Island


cg26574680
chr1: 235811860
GNG4.UTR5
SCLC-I
F
chr1: 235811841-
Island







235814066


cg26627129
chr19: 49552470
CGB8.TSS200
SCLC-I
F


cg00102996
chr9: 92220617
GADD45G.GENEBODY
SCLC-I
R
chr9: 92219771-
Island







92221411


cg01589998
chr12: 109729478
FOXN4.GENEBODY
SCLC-I
R
chr12: 109729572-
N_Shore







109729826


cg01994275
chr7: 8480586
NXPH1.GENEBODY
SCLC-I
F
chr7: 8481974-8482762
N_Shore


cg04013592
chr3: 63263076
SYNPR.TSS1500
SCLC-I
F
chr3: 63263989-
N_Shore







63264205


cg05848863
chr7: 16794078
TSPAN13.GENEBODY
SCLC-I
R
chr7: 16793188-
Island







16794100


cg09649438
chr10: 81904160
PLAC9.GENEBODY
SCLC-I
R


cg13223402
chr2: 47797133
KCNK12.EXON1
SCLC-I
R
chr2: 47796923-
Island







47799166


cg13827782
chr9: 93377568
DIRAS2.UTR5
SCLC-I
R


cg13978352
chr6: 30908706
DPCR1.TSS200
SCLC-I
R


cg14750475
chr19: 50139654
RRAS.GENEBODY
SCLC-I
F
chr19: 50143223-
N_Shelf







50143975


cg15954675
chr3: 63542363
SYNPR.GENEBODY
SCLC-I
R


cg19195419
chr19: 1799935
ATP8B3.GENEBODY
SCLC-I
R
chr19: 1799934-1800248
Island


cg20083442
chr8: 73600575
KCNB2.GENEBODY
SCLC-I
R


cg20353496
chr20: 825268
FAM110A.TSS200
SCLC-I
R
chr20: 825267-826276
Island


cg21574349
chr3: 185080951
MAP3K13.TSS200
SCLC-I
F


cg23422361
chr10: 135143617
CALY.UTR5
SCLC-I
F
chr10: 135143373-
S_Shore







135143580


cg23463608
chr19: 2607757
GNG7.UTR5
SCLC-I
F
chr19: 2607725-2607967
Island


cg27233151
chr4: 82057467
PRKG2.GENEBODY
SCLC-I
R


cg02365303
chr5: 147052498
JAKMIP2.UTR5
SCLC-I
F


cg08694699
chr16: 68270282
ESRP2.TSS200
SCLC-I
F
chr16: 68269010-
Island







68272143


cg20668718
chr5: 146991927
JAKMIP2.GENEBODY
SCLC-I
F


cg20818262
chr8: 73480145
KCNB2.GENEBODY
SCLC-I
R


cg22459924
chr19: 2607850
GNG7.UTR5
SCLC-I
F
chr19: 2607725-2607967
Island


cg11610754
chr19: 18722595
TMEM59L.TSS1500
SCLC-I
R
chr19: 18722358-
Island







18724001


cg12053155
chr13: 107186476
EFNB2.GENEBODY
SCLC-I
R
chr13: 107186468-
Island







107189024


cg12232903
chr4: 10686413
CLNK.TSS200
SCLC-I
F


cg14995475
chr19: 6534774
TNFSF9.GENEBODY
SCLC-I
R
chr19: 6534759-6535079
Island


cg16661000
chr15: 89437710
HAPLN3.UTR5
SCLC-I
F
chr15: 89438176-
N_Shore







89438850


cg17208427
chr16: 68679556
CDH3.GENEBODY
SCLC-I
R
chr16: 68678686-
Island







68680149


cg18721026
chr3: 183948313
VWA5B2.TSS200
SCLC-I
F
chr3: 183947040-
Island







183948801


cg00090619
chr6: 33160286
COL11A2.TSS200
SCLC-I
F
chr6: 33160945-
N_Shore







33161337


cg00106565
chr5: 146784171
DPYSL3.GENEBODY
SCLC-I
F


cg00303541
chr3: 51741280
GRM2.UTR5
SCLC-I
R
chr3: 51740740-
Island







51741413


cg01177388
chr6: 32812704
PSMB8.UTR5
SCLC-I
F
chr6: 32811494-
S_Shore







32811839


cg01294327
chr19: 2291373
LINGO3.GENEBODY
SCLC-I
R
chr19: 2289895-2291904
Island


cg02688752
chr5: 76115309
F2RL1.GENEBODY
SCLC-I
R
chr5: 76115510-
N_Shore







76116089


cg02969706
chr2: 6072283
LOC150622.TSS1500
SCLC-I
R


cg03225210
chr7: 143579951
FAM115A.UTR5
SCLC-I
R
chr7: 143582125-
N_Shelf







143582610


cg04458159
chr6: 29856538
HLA-H.GENEBODY
SCLC-I
F
chr6: 29855295-
Island







29856565


cg04872123
chr6: 32049699
TNXB.GENEBODY
SCLC-I
R
chr6: 32046815-
S_Shelf







32047094


cg05057976
chr11: 65779667
CST6.EXON1
SCLC-I
F
chr11: 65779311-
Island







65779767


cg06321045
chr6: 31088343
CDSN.TSS200
SCLC-I
F


cg06529264
chr13: 54887288
MIR1297.TSS1500
SCLC-I
F


cg07435445
chr14: 103396379
AMN.GENEBODY
SCLC-I
R
chr14: 103394397-
Island







103397070


cg08551725
chr7: 30029776
SCRN1.TSS1500
SCLC-I
F
chr7: 30028518-
Island







30029822


cg11606261
chr12: 53775336
SP1.UTR5
SCLC-I
R
chr12: 53774336-
S_Shore







53774603


cg11794801
chr8: 10262020
MSRA.GENEBODY
SCLC-I
R
chr8: 10261900-
Island







10262222


cg11941546
chr17: 7165842
CLDN7.TSS200
SCLC-I
R
chr17: 7164285-7166245
Island


cg13083674
chr19: 55953372
SHISA7.GENEBODY
SCLC-I
R
chr19: 55953371-
Island







55954641


cg13470920
chr19: 6772831
VAV1.EXON1
SCLC-I
F


cg13723983
chr9: 132383362
C9orf50.TSS1500
SCLC-I
F
chr9: 132382432-
S_Shore







132383004


cg13851989
chr9: 14720244
CER1.GENEBODY
SCLC-I
R


cg13984492
chr9: 104031694
LPPR1.GENEBODY
SCLC-I
R


cg15705054
chr1: 154927709
PBXIP1.UTR5
SCLC-I
R


cg17930034
chr14: 65016602
C14orf50.TSS200
SCLC-I
R
chr14: 65016516-
Island







65016909


cg20114890
chr6: 29856430
HLA-H.GENEBODY
SCLC-I
R
chr6: 29855295-
Island







29856565


cg21476000
chr12: 54430684
HOXC4.UTR5
SCLC-I
F
chr12: 54427025-
S_Shore







54428709


cg21552300
chr2: 175629224
CHRNA1.TSS200
SCLC-I
F


cg23292266
chr19: 11285128
KANK2.GENEBODY
SCLC-I
R
chr19: 11285122-
Island







11285332


cg23517605
chr6: 3228365
TUBB2B.TSS1500
SCLC-I
F
chr6: 3227025-3229688
Island


cg24735489
chr6: 31088352
CDSN.TSS200
SCLC-I
F


cg25036095
chr4: 82392410
RASGEF1B.UTR5
SCLC-I
F
chr4: 82392610-
N_Shore







82393426


cg25580825
chr19: 10116808
COL5A3.GENEBODY
SCLC-I
F
chr19: 10120750-
N_Shelf







10121231


cg25661884
chr19: 10124267
RDH8.EXON1
SCLC-I
R
chr19: 10120750-
S_Shelf







10121231


cg25751198
chr12: 109729573
FOXN4.GENEBODY
SCLC-I
R
chr12: 109729572-
Island







109729826


cg00378510
chr19: 2291020
LINGO3.GENEBODY
SCLC-I
F
chr19: 2289895-2291904
Island


cg17259886
chr5: 147040667
JAKMIP2.GENEBODY
SCLC-I
F


cg00961418
chr11: 8616172
STK33.TSS1500
SCLC-I
F
chr11: 8615397-8615889
S_Shore


cg01218350
chr2: 210517441
MAP2.UTR5
SCLC-I
R


cg01974715
chr19: 41724129
AXL.TSS1500
SCLC-I
F


cg02374996
chr9: 92220771
GADD45G.GENEBODY
SCLC-I
F
chr9: 92219771-
Island







92221411


cg03250393
chr19: 41735107
AXL.GENEBODY
SCLC-I
F
chr19: 41732006-
S_Shelf







41732556


cg03436967
chr7: 147207052
MIR54814.GENEBODY
SCLC-I
F


cg03549571
chr12: 49488198
DHH.EXON1
SCLC-I
R
chr12: 49487963-
Island







49488202


cg03832506
chrX: 53286187
IQSEC2.GENEBODY
SCLC-I
R
chrX: 53283829-
S_Shelf







53284038


cg04328477
chr16: 68270258
ESRP2.TSS200
SCLC-I
F
chr16: 68269010-
Island







68272143


cg05171933
chr5: 147205668
SPINK1.GENEBODY
SCLC-I
F


cg06193043
chr1: 11908199
NPPA.TSS1500
SCLC-I
F


cg06205574
chr12: 23858674
SOX5.GENEBODY
SCLC-I
F


cg06671964
chr6: 32052105
TNXB.GENEBODY
SCLC-I
F
chr6: 32055067-
N_Shelf







32055601


cg06723863
chr16: 68270129
ESRP2.EXON1
SCLC-I
F
chr16: 68269010-
Island







68272143


cg07896312
chr8: 22409062
SORBS3.TSS200
SCLC-I
R
chr8: 22408672-
Island







22409635


cg08416875
chr6: 119669226
MAN1A1.GENEBODY
SCLC-I
R
chr6: 119669589-
N_Shore







119671424


cg08575922
chr12: 49488082
DHH.EXON1
SCLC-I
R
chr12: 49487963-
Island







49488202


cg09807148
chr17: 34122069
MMP28.GENEBODY
SCLC-I
F
chr17: 34122024-
Island







34122801


cg09990600
chr7: 1596103
TMEM184A.TSS200
SCLC-I
R


cg10030250
chr16: 55540152
MMP2.UTR3
SCLC-I
F
chr16: 55542920-
N_Shelf







55543274


cg10131879
chr7: 8011594
GLCCI1.GENEBODY
SCLC-I
F
chr7: 8008097-8009495
S_Shelf


cg10688790
chr7: 147591961
MIR548F3.TSS1500
SCLC-I
R


cg11384924
chr6: 33160224
COL11A2.UTR5
SCLC-I
F
chr6: 33159991-
Island







33160263


cg11664251
chr2: 149634581
KIF5C.GENEBODY
SCLC-I
R
chr2: 149632682-
S_Shore







149633882


cg11989343
chr13: 53287193
LECT1.GENEBODY
SCLC-I
R


cg12444861
chr6: 144386275
PLAGL1.TSS1500
SCLC-I
F
chr6: 144384894-
S_Shore







144385888


cg12626076
chr15: 92399195
SLCO3A1.GENEBODY
SCLC-I
F
chr15: 92396013-
S_Shore







92397682


cg13586420
chr6: 33160262
COL11A2.TSS200
SCLC-I
F
chr6: 33159991-
Island







33160263


cg13969788
chr9: 35689475
TPM2.GENEBODY
SCLC-I
F
chr9: 35689610-
N_Shore







35691101


cg14011070
chr1: 235811811
GNG4.UTR5
SCLC-I
R
chr1: 235811841-
N_Shore







235814066


cg14627974
chr7: 147188028
MIR54814.GENEBODY
SCLC-I
F


cg15558616
chr3: 173630182
NLGN1.GENEBODY
SCLC-I
R


cg15678504
chr8: 10262159
MSRA.GENEBODY
SCLC-I
R
chr8: 10261900-
Island







10262222


cg15712559
chr20: 58180616
PHACTR3.GENEBODY
SCLC-I
F
chr20: 58179808-
Island







58180787


cg15982299
chr6: 31097078
PSORS1C1.UTR5
SCLC-I
F


cg16014168
chr12: 109729677
FOXN4.GENEBODY
SCLC-I
F
chr12: 109729572-
Island







109729826


cg16911349
chr19: 10406935
ICAM5.GENEBODY
SCLC-I
R
chr19: 10406934-
Island







10407342


cg18216587
chr7: 146019420
CNTNAP2.GENEBODY
SCLC-I
F


cg18516816
chr19: 30165591
PLEKHF1.UTR3
SCLC-I
F
chr19: 30164768-
S_Shore







30165556


cg19047707
chr2: 233351525
ECEL1.UTR5
SCLC-I
R
chr2: 233350278-
Island







233352974


cg20010135
chr16: 30996822
HSD3B7.UTR5
SCLC-I
F


cg20330126
chr22: 36125053
APOL5.UTR3
SCLC-I
F


cg21446725
chr12: 49740996
DNAJC22.TSS200
SCLC-I
R
chr12: 49738680-
S_Shore







49740841


cg22857356
chr19: 8398590
KANK3.GENEBODY
SCLC-I
R
chr19: 8397958-8400461
Island


cg23097961
chr19: 49055412
SULT2B1.TSS200
SCLC-I
F


cg23344395
chr3: 192634002
C3orf59.GENEBODY
SCLC-I
R
chr3: 192634309-
N_Shore







192635967


cg23623622
chr6: 30139880
TRIM15.GENEBODY
SCLC-I
F
chr6: 30139718-
Island







30140263


cg23764900
chr11: 8616102
STK33.TSS1500
SCLC-I
R
chr11: 8615397-8615889
S_Shore


cg23883945
chr7: 36749772
AOAH.GENEBODY
SCLC-I
F


cg23937993
chr11: 10477847
AMPD3.EXON1
SCLC-I
F


cg24021846
chr7: 103556529
RELN.GENEBODY
SCLC-I
F


cg24952408
chr6: 29696264
LOC285830.GENEBODY
SCLC-I
F


cg25934371
chr3: 63427866
SYNPR.GENEBODY
SCLC-I
F


cg27023555
chr2: 233351735
ECEL1.UTR5
SCLC-I
R
chr2: 233350278-
Island







233352974


cg27108362
chr12: 49488554
DHH.UTR5
SCLC-I
F
chr12: 49487963-
S_Shore







49488202


cg27181765
chr6: 33160250
COL11A2.TSS200
SCLC-I
F
chr6: 33159991-
Island







33160263


cg01635061
chr6: 33160234
COL11A2.UTR5
SCLC-I
F
chr6: 33159991-
Island







33160263


cg02582213
chr16: 89441654
ANKRD11.UTR5
SCLC-I
F
chr16: 89438503-
S_Shelf







89438850


cg02628840
chr21: 46860579
COL18A1.GENEBODY
SCLC-I
R
chr21: 46860366-
Island







46860628


cg06712559
chr1: 968395
AGRN.GENEBODY
SCLC-I
F
chr1: 967966-970238
Island


cg09235583
chr6: 30711141
IER3.UTR3
SCLC-I
F
chr6: 30710307-
Island







30712440


cg20931195
chr17: 708009
NXN.GENEBODY
SCLC-I
F
chr17: 708319-708598
N_Shore


cg25549619
chr5: 147154246
JAKMIP2.UTR5
SCLC-I
F


cg27480819
chr12: 23686149
SOX5.UTR3
SCLC-I
R


cg00201445
chr3: 192634310
C3orf59.GENEBODY
SCLC-I
R
chr3: 192634309-
Island







192635967


cg00650953
chr7: 147500503
CNTNAP2.GENEBODY
SCLC-I
R


cg00698688
chr19: 49055432
SULT2B1.EXON1
SCLC-I
F


cg00965643
chr1: 32674817
DCDC2B.EXON1
SCLC-I
F
chr1: 32670569-
S_Shelf







32671885


cg00974598
chr19: 44223902
IRGC.GENEBODY
SCLC-I
R
chr19: 44222858-
Island







44223943


cg01030534
chr7: 143579698
FAM115A.UTR5
SCLC-I
F
chr7: 143582125-
N_Shelf







143582610


cg01243297
chr6: 33160292
COL11A2.TSS200
SCLC-I
F
chr6: 33160945-
N_Shore







33161337


cg02633149
chr17: 81042782
METRNL.GENEBODY
SCLC-I
R
chr17: 81042626-
Island







81043244


cg03039843
chr19: 49055390
SULT2B1.TSS200
SCLC-I
R


cg03485217
chr4: 10686300
CLNK.EXON1
SCLC-I
R


cg03607415
chr5: 89881642
GPR98.GENEBODY
SCLC-I
R


cg03761471
chr7: 143077178
ZYX.TSS1500
SCLC-I
F
chr7: 143077469-
N_Shore







143079169


cg03936135
chr16: 86371248
LOC732275.GENEBODY
SCLC-I
F


cg04601383
chr19: 6713459
C3.GENEBODY
SCLC-I
R
chr19: 6710625-6710828
S_Shelf


cg05681757
chr12: 32655034
FGD4.TSS200
SCLC-I
R


cg06822340
chr7: 147355839
CNTNAP2.GENEBODY
SCLC-I
R


cg06852032
chr17: 25976191
LGALS9.GENEBODY
SCLC-I
F


cg07001963
chr10: 44879465
CXCL12.GENEBODY
SCLC-I
R
chr10: 44879714-
N_Shore







44882391


cg07095230
chr17: 59480730
TBX2.GENEBODY
SCLC-I
F
chr17: 59473060-
Island







59483266


cg07152605
chr1: 164793520
PBX1.GENEBODY
SCLC-I
R


cg07270851
chr11: 65779332
CST6.TSS200
SCLC-I
F
chr11: 65779311-
Island







65779767


cg07287698
chr12: 97957454
MIR135A2.TSS200
SCLC-I
F


cg08787401
chr2: 222383520
EPHA4.GENEBODY
SCLC-I
F


cg09225457
chr7: 8479893
NXPH1.GENEBODY
SCLC-I
R
chr7: 8481974-8482762
N_Shelf


cg09932135
chr1: 11750569
MAD2L2.UTR5
SCLC-I
F
chr1: 11750701-
N_Shore







11752651


cg11904429
chr19: 6592554
CD70.TSS1500
SCLC-I
F
chr19: 6590340-6591072
S_Shore


cg12197421
chr6: 30653736
KIAA1949.GENEBODY
SCLC-I
F
chr6: 30654392-
N_Shore







30654934


cg12747860
chr6: 3229027
TUBB2B.TSS1500
SCLC-I
R
chr6: 3227025-3229688
Island


cg12805420
chr17: 7165840
CLDN7.TSS200
SCLC-I
R
chr17: 7164285-7166245
Island


cg12967164
chr7: 1753637
ELFN1.UTR5
SCLC-I
F
chr7: 1753446-1753706
Island


cg13094252
chr8: 104153753
C8orf56.TSS200
SCLC-I
R
chr8: 104152726-
S_Shore







104153390


cg13673837
chr19: 15306670
NOTCH3.GENEBODY
SCLC-I
F
chr19: 15306243-
Island







15307111


cg14282850
chr10: 123924917
TACC2.GENEBODY
SCLC-I
F
chr10: 123922850-
S_Shore







123923542


cg14347177
chr11: 65779330
CST6.TSS200
SCLC-I
F
chr11: 65779311-
Island







65779767


cg14574369
chr12: 57483631
NAB2.GENEBODY
SCLC-I
R
chr12: 57480797-
S_Shore







57483116


cg14663984
chr1: 969042
AGRN.GENEBODY
SCLC-I
F
chr1: 967966-970238
Island


cg15633699
chr1: 1356728
LOC441869.TSS200
SCLC-I
F
chr1: 1355159-1356000
S_Shore


cg16663570
chr8: 22014724
LGI3.TSS1500
SCLC-I
F
chr8: 22014152-
S_Shore







22014559


cg16713727
chr1: 16062720
SLC25A34.TSS200
SCLC-I
R


cg17928920
chr1: 968558
AGRN.GENEBODY
SCLC-I
R
chr1: 967966-970238
Island


cg18425731
chr2: 158184641
ERMN.TSS1500
SCLC-I
F


cg19092045
chr13: 54887369
MIR1297.TSS1500
SCLC-I
R


cg19244428
chr6: 3229233
TUBB2B.TSS1500
SCLC-I
R
chr6: 3227025-3229688
Island


cg19791630
chr19: 6772811
VAV1.UTR5
SCLC-I
F


cg20308663
chr13: 100523121
CLYBL.GENEBODY
SCLC-I
F


cg20561300
chr15: 93189780
FAM174B.GENEBODY
SCLC-I
R


cg21131024
chr8: 104153643
C8orf56.TSS200
SCLC-I
F
chr8: 104152726-
S_Shore







104153390


cg21422016
chr7: 1753659
ELFN1.UTR5
SCLC-I
R
chr7: 1753446-1753706
Island


cg22156128
chr3: 10327453
GHRL.GENEBODY
SCLC-I
R


cg22431093
chr12: 32654992
FGD4.TSS200
SCLC-I
R


cg23049291
chr1: 165204745
LMX1A.GENEBODY
SCLC-I
F
chr1: 165204501-
Island







165205507


cg26080567
chr21: 37536137
DOPEY2.TSS1500
SCLC-I
R


cg26190885
chr19: 45409005
APOE.TSS200
SCLC-I
F
chr19: 45411720-
N_Shelf







45412600


cg26638341
chr19: 1800126
ATP8B3.GENEBODY
SCLC-I
F
chr19: 1799934-1800248
Island


cg26737640
chr19: 6587584
CD70.GENEBODY
SCLC-I
F
chr19: 6590340-6591072
N_Shelf


cg26946905
chr16: 89441595
ANKRD11.UTR5
SCLC-I
F
chr16: 89438503-
S_Shelf







89438850


cg26993132
chr16: 89239499
CDH15.GENEBODY
SCLC-I
F
chr16: 89237944-
S_Shore







89238331


cg27082921
chr19: 1800150
ATP8B3.GENEBODY
SCLC-I
R
chr19: 1799934-1800248
Island


cg02349785
chr11: 65778967
CST6.TSS1500
SCLC-I
R
chr11: 65779311-
N_Shore







65779767


cg02576092
chr1: 27668556
SYTL1.EXON1
SCLC-I
R


cg04327181
chr11: 65779526
CST6.EXON1
SCLC-I
F
chr11: 65779311-
Island







65779767


cg04626868
chr12: 23999034
SOX5.GENEBODY
SCLC-I
R


cg05601974
chr7: 150941389
SMARCD3.GENEBODY
SCLC-I
F
chr7: 150942304-
N_Shore







150943033


cg09482611
chr11: 65779263
CST6.TSS200
SCLC-I
R
chr11: 65779311-
N_Shore







65779767


cg14452346
chr5: 147212032
SPINK1.TSS1500
SCLC-I
F


cg19296556
chr19: 1802918
ATP8B3.GENEBODY
SCLC-I
F
chr19: 1799934-1800248
S_Shelf


cg24478779
chr2: 6110966
LOC150622.GENEBODY
SCLC-I
R


cg04016660
chr16: 85075232
KIAA0513.UTR5
SCLC-I
R


cg00107982
chr22: 37813098
ELFN2.UTR5
SCLC-I
F
chr22: 37815803-
N_Shelf







37816477


cg00135874
chr2: 210493473
MAP2.UTR5
SCLC-I
R


cg00464796
chr15: 53852614
WDR72.GENEBODY
SCLC-I
F


cg01084435
chr16: 58535556
NDRG4.GENEBODY
SCLC-I
F
chr16: 58535040-
Island







58535596


cg03992611
chr15: 92397873
SLCO3A1.GENEBODY
SCLC-I
R
chr15: 92396013-
S_Shore







92397682


cg04080448
chr12: 97924358
RMST.GENEBODY
SCLC-I
F


cg05393025
chr1: 20141781
RNF186.TSS200
SCLC-I
R


cg06189653
chr5: 176873332
PRR7.TSS1500
SCLC-I
R
chr5: 176873349-
N_Shore







176874737


cg06705685
chr2: 8116961
LOC339788.TSS200
SCLC-I
F


cg08151612
chr19: 49055438
SULT2B1.EXON1
SCLC-I
R


cg08966208
chr11: 1769409
HCCA2.GENEBODY
SCLC-I
F
chr11: 1768979-1770712
Island


cg11406274
chr6: 29856564
HLA-H.GENEBODY
SCLC-I
F
chr6: 29855295-
Island







29856565


cg11736020
chr6: 30651511
KIAA1949.GENEBODY
SCLC-I
R
chr6: 30654392-
N_Shelf







30654934


cg11920519
chr20: 33135025
MAP1LC3A.UTR5
SCLC-I
R


cg12570246
chr7: 36959356
MIR1200.TSS1500
SCLC-I
F


cg12732715
chr1: 148929740
LOC645166.TSS1500
SCLC-I
F


cg12781794
chr11: 118505740
PHLDB1.GENEBODY
SCLC-I
F
chr11: 118505508-
Island







118505741


cg13729891
chr17: 7108468
DLG4.GENEBODY
SCLC-I
F
chr17: 7108304-7108654
Island


cg13951572
chr8: 22409000
SORBS3.TSS1500
SCLC-I
F
chr8: 22408672-
Island







22409635


cg14089943
chr10: 103990076
PITX3.UTR3
SCLC-I
R
chr10: 103990213-
N_Shore







103991829


cg14279361
chr19: 6721955
C3.TSS1500
SCLC-I
R


cg14397690
chr15: 60688948
ANXA2.UTR5
SCLC-I
F
chr15: 60689749-
N_Shore







60690430


cg14492061
chr3: 63637129
SNTN.TSS1500
SCLC-I
R


cg14899716
chr1: 42846987
RIMKLA.GENEBODY
SCLC-I
F
chr1: 42845978-
Island







42846988


cg15249911
chr19: 41634046
CYP2F1.UTR3
SCLC-I
R
chr19: 41633776-
Island







41634047


cg15507500
chr19: 17605696
SLC27A1.GENEBODY
SCLC-I
F
chr19: 17607983-
N_Shelf







17608406


cg16094352
chr14: 24642317
REC8.GENEBODY
SCLC-I
R
chr14: 24641053-
S_Shore







24642220


cg16318112
chr1: 969254
AGRN.GENEBODY
SCLC-I
F
chr1: 967966-970238
Island


cg16706099
chr11: 10059019
FLJ32810.GENEBODY
SCLC-I
F



7


cg17058616
chr17: 73102145
SLC16A5.UTR3
SCLC-I
R
chr17: 73105229-
N_Shelf







73106667


cg17610929
chr2: 220379044
ACCN4.UTR5
SCLC-I
R
chr2: 220377743-
S_Shore







220377946


cg17826168
chr19: 6464103
CRB3.TSS200
SCLC-I
F
chr19: 6463991-6464780
Island


cg17945153
chr6: 41978288
CCND3.UTR5
SCLC-I
R


cg19260567
chr7: 147303836
CNTNAP2.GENEBODY
SCLC-I
F


cg20855296
chr17: 16255560
CENPV.GENEBODY
SCLC-I
R
chr17: 16255618-
N_Shore







16257148


cg21061582
chr18: 44498047
PIAS2.TSS1500
SCLC-I
F
chr18: 44496910-
S_Shore







44497832


cg21238061
chr9: 104036809
LPPR1.GENEBODY
SCLC-I
R


cg22365276
chr15: 60688622
ANXA2.UTR5
SCLC-I
R
chr15: 60689749-
N_Shore







60690430


cg22376856
chr1: 204643556
LRRN2.UTR5
SCLC-I
R


cg22862634
chr11: 62369728
EML3.UTR3
SCLC-I
R
chr11: 62368454-
Island







62370491


cg23214395
chr1: 20141778
RNF186.TSS200
SCLC-I
R


cg23265500
chr14: 65016591
C14orf50.TSS200
SCLC-I
R
chr14: 65016516-
Island







65016909


cg23912509
chr12: 97957406
MIR135A2.TSS200
SCLC-I
F


cg24556026
chr9: 36258971
GNE.TSS1500
SCLC-I
F
chr9: 36258170-
S_Shore







36258886


cg24723883
chr19: 2608495
GNG7.UTR5
SCLC-I
F
chr19: 2607725-2607967
S_Shore


cg25124058
chr12: 97886218
RMST.GENEBODY
SCLC-I
F


cg26633373
chr19: 54377836
MYADM.UTR3
SCLC-I
R
chr19: 54377172-
S_Shore







54377441


cg26660800
chr17: 59480926
TBX2.GENEBODY
SCLC-I
F
chr17: 59473060-
Island







59483266


cg00187437
chr6: 31089157
CDSN.TSS1500
SCLC-I
R


cg00294550
chr10: 62144786
ANK3.GENEBODY
SCLC-I
F


cg02447471
chr7: 95537015
DYNC111.GENEBODY
SCLC-I
F


cg11243173
chr12: 23999045
SOX5.GENEBODY
SCLC-I
R


cg14894216
chr11: 65794352
CATSPER1.TSS1500
SCLC-I
R


cg17295739
chr6: 32049513
TNXB.GENEBODY
SCLC-I
R
chr6: 32046815-
S_Shelf







32047094


cg24283921
chr11: 10477461
AMPD3.TSS200
SCLC-I
F


cg26070020
chr1: 165201385
LMX1A.GENEBODY
SCLC-I
F
chr1: 165204501-
N_Shelf







165205507


cg27248041
chr6: 93992464
EPHA7.GENEBODY
SCLC-I
F


cg03514404
chr7: 143579665
FAM115A.UTR5
SCLC-I
F
chr7: 143582125-
N_Shelf







143582610


cg00151914
chr17: 34058550
RASL10B.TSS200
SCLC-I
R
chr17: 34058549-
Island







34058778


cg00721771
chr3: 59903821
FHIT.GENEBODY
SCLC-I
F


cg00784153
chr19: 10077007
COL5A3.GENEBODY
SCLC-I
R
chr19: 10077031-
N_Shore







10077444


cg00957688
chr1: 36183672
C1orf216.UTR5
SCLC-I
F
chr1: 36184248-
N_Shore







36184774


cg01110620
chr12: 113573312
RASAL1.UTR5
SCLC-I
F
chr12: 113572977-
Island







113573758


cg01538731
chr16: 87757018
KLHDC4.GENEBODY
SCLC-I
F
chr16: 87754008-
S_Shelf







87754285


cg01794802
chr6: 31096931
PSORS1C1.UTR5
SCLC-I
R


cg02004418
chr2: 45236740
SIX2.TSS200
SCLC-I
R
chr2: 45235511-
Island







45237792


cg02227919
chr2: 171569132
LOC440925.GENEBODY
SCLC-I
R
chr2: 171569877-
N_Shore







171573904


cg02849309
chr6: 144386280
PLAGL1.TSS1500
SCLC-I
F
chr6: 144384894-
S_Shore







144385888


cg02916272
chr11: 1769443
HCCA2.GENEBODY
SCLC-I
F
chr11: 1768979-1770712
Island


cg03153115
chr19: 2604559
GNG7.UTR5
SCLC-I
F
chr19: 2607725-2607967
N_Shelf


cg03207915
chr6: 119669112
MAN1A1.GENEBODY
SCLC-I
F
chr6: 119669589-
N_Shore







119671424


cg03546687
chr16: 2198080
RAB26.TSS1500
SCLC-I
R
chr16: 2198455-2199129
N_Shore


cg04396998
chr19: 49376722
PPP1R15A.GENEBODY
SCLC-I
R
chr19: 49375484-
S_Shore







49375928


cg04475868
chr16: 86380594
LOC732275.TSS1500
SCLC-I
F


cg04742671
chr19: 54781049
LILRB2.GENEBODY
SCLC-I
R


cg05301811
chr1: 20813666
CAMK2N1.TSS1500
SCLC-I
F
chr1: 20810462-
S_Shore







20813511


cg05484788
chr20: 58180357
PHACTR3.GENEBODY
SCLC-I
F
chr20: 58179808-
Island







58180787


cg06303936
chr3: 172711298
SPATA16.GENEBODY
SCLC-I
F


cg07629125
chr13: 58299015
PCDH17.GENEBODY
SCLC-I
R


cg08247297
chr21: 46917541
COL18A1.GENEBODY
SCLC-I
F
chr21: 46918188-
N_Shore







46918410


cg08269485
chr11: 1769382
HCCA2.GENEBODY
SCLC-I
F
chr11: 1768979-1770712
Island


cg08550882
chr11: 12308354
MICALCL.TSS200
SCLC-I
R


cg09708598
chr13: 54887314
MIR1297.TSS1500
SCLC-I
F


cg10303653
chr6: 32049516
TNXB.GENEBODY
SCLC-I
R
chr6: 32046815-
S_Shelf







32047094


cg10560147
chr11: 65779335
CST6.TSS200
SCLC-I
F
chr11: 65779311-
Island







65779767


cg12432038
chr1: 247275735
C1orf229.TSS200
SCLC-I
R
chr1: 247274585-
Island







247275757


cg13064679
chr6: 32049953
TNXB.GENEBODY
SCLC-I
R
chr6: 32046815-
S_Shelf







32047094


cg13095737
chr5: 177034964
B4GALT7.GENEBODY
SCLC-I
R
chr5: 177035351-
N_Shore







177035660


cg15005677
chr11: 45918197
MAPK8IP1.GENEBODY
SCLC-I
R
chr11: 45921387-
N_Shelf







45922167


cg15144888
chr11: 128760367
KCNJ5.TSS1500
SCLC-I
F
chr11: 128760441-
N_Shore







128761233


cg15323252
chr8: 22436420
PDLIM2.TSS1500
SCLC-I
R
chr8: 22436295-
Island







22437076


cg16317181
chr10: 85954559
PCDH21.EXON1
SCLC-I
R
chr10: 85954199-
Island







85955303


cg17765324
chr12: 16359122
SLC15A5.GENEBODY
SCLC-I
F


cg18320766
chr19: 55598782
EPS8L1.GENEBODY
SCLC-I
R
chr19: 55597977-
Island







55598887


cg19455335
chr8: 22457658
C8orf58.GENEBODY
SCLC-I
R
chr8: 22457123-
Island







22457753


cg19961803
chr11: 65554928
OVOL1.EXON1
SCLC-I
F
chr11: 65553749-
Island







65555573


cg20383948
chr21: 46898137
COL18A1.GENEBODY
SCLC-I
R
chr21: 46897841-
Island







46898158


cg21475065
chr7: 147336337
CNTNAP2.GENEBODY
SCLC-I
R


cg22153696
chr4: 186389425
CCDC110.GENEBODY
SCLC-I
F
chr4: 186392574-
N_Shelf







186393184


cg22287800
chr7: 8634300
NXPH1.GENEBODY
SCLC-I
F


cg24042496
chr11: 117497929
DSCAML1.GENEBODY
SCLC-I
R


cg24990327
chr7: 147591897
MIR548F3.TSS1500
SCLC-I
R


cg25317941
chr2: 233351153
ECEL1.GENEBODY
SCLC-I
R
chr2: 233350278-
Island







233352974


cg26104986
chr11: 75275303
SERPINH1.UTR5
SCLC-I
F
chr11: 75272950-
S_Shore







75273616


cg27579097
chr16: 734844
JMJD8.TSS1500
SCLC-I
R
chr16: 729438-735815
Island


cg04486528
chr7: 147727995
MIR548F3.GENEBODY
SCLC-I
F


cg07047570
chr20: 20350813
INSM1.EXON1
SCLC-I
F
chr20: 20344400-
S_Shore







20350605


cg07912147
chr12: 26138851
RASSF8.UTR5
SCLC-I
R


cg09246103
chr1: 8456466
RERE.UTR5
SCLC-I
R


cg09247061
chr16: 88571844
ZFPM1.GENEBODY
SCLC-I
F
chr16: 88573285-
N_Shore







88573489


cg09365529
chr1: 75140289
C1orf173.TSS1500
SCLC-I
F


cg14950855
chr12: 49740781
DNAJC22.TSS1500
SCLC-I
F
chr12: 49738680-
Island







49740841


cg15262242
chr17: 47301741
PHOSPHO1.GENEBODY
SCLC-I
R
chr17: 47301545-
Island







47302477


cg15802396
chr17: 7108305
DLG4.GENEBODY
SCLC-I
R
chr17: 7108304-7108654
Island


cg16182479
chr17: 41832466
SOST.UTR3
SCLC-I
R
chr17: 41832717-
N_Shore







41833195


cg16630229
chr6: 33160604
COL11A2.TSS1500
SCLC-I
F
chr6: 33160945-
N_Shore







33161337


cg18395327
chr2: 220379109
ACCN4.EXON1
SCLC-I
R
chr2: 220377743-
S_Shore







220377946


cg19822502
chr6: 97456581
KLHL32.GENEBODY
SCLC-I
F


cg22189307
chr11: 61061699
VWCE.GENEBODY
SCLC-I
R
chr11: 61061751-
N_Shore







61063063


cg23619910
chr11: 10477452
AMPD3.TSS200
SCLC-I
R


cg24155984
chr5: 66127678
MAST4.GENEBODY
SCLC-I
F


cg26578983
chr16: 85075249
KIAA0513.UTR5
SCLC-I
R


cg00691368
chr6: 30909820
DPCR1.GENEBODY
SCLC-I
F


cg00988129
chr8: 75232556
JPH1.GENEBODY
SCLC-I
R
chr8: 75232649-
N_Shore







75234101


cg03716590
chr7: 95435309
DYNC111.GENEBODY
SCLC-I
R


cg04770813
chr6: 33160297
COL11A2.TSS200
SCLC-I
F
chr6: 33160945-
N_Shore







33161337


cg05273302
chr19: 2095560
C19orf36.TSS1500
SCLC-I
F
chr19: 2095395-2095727
Island


cg06212760
chr1: 46664937
POMGNT1.GENEBODY
SCLC-I
R
chr1: 46668821-
N_Shelf







46669258


cg07308243
chr16: 85074963
KIAA0513.UTR5
SCLC-I
R


cg07409292
chr4: 90228685
GPRIN3.UTR5
SCLC-I
R
chr4: 90228714-
N_Shore







90229010


cg08531687
chr5: 89968232
GPR98.GENEBODY
SCLC-I
F


cg09335647
chr7: 147097440
MIR54814.GENEBODY
SCLC-I
F


cg10332715
chr1: 245017736
HNRNPU.UTR3
SCLC-I
F


cg10383447
chr16: 58535093
NDRG4.GENEBODY
SCLC-I
F
chr16: 58535040-
Island







58535596


cg10632765
chr19: 6534916
TNFSF9.GENEBODY
SCLC-I
F
chr19: 6534759-6535079
Island


cg12046414
chr2: 220379199
ACCN4.EXON1
SCLC-I
R
chr2: 220377743-
S_Shore







220377946


cg12489353
chr19: 48231499
EHD2.GENEBODY
SCLC-I
F
chr19: 48229072-
S_Shore







48229507


cg13455326
chr19: 10043341
OLFM2.GENEBODY
SCLC-I
R
chr19: 10046824-
N_Shelf







10047067


cg14098532
chr3: 111717874
TAGLN3.TSS200
SCLC-I
F


cg14478768
chr19: 1083429
HMHA1.GENEBODY
SCLC-I
F
chr19: 1082576-1083430
Island


cg15939253
chr11: 66049932
CNIH2.GENEBODY
SCLC-I
F
chr11: 66049750-
Island







66050229


cg16678522
chr20: 32149963
CBFA2T2.GENEBODY
SCLC-I
F


cg17831934
chr7: 147264850
CNTNAP2.GENEBODY
SCLC-I
R


cg17894318
chr3: 181441384
SOX2OT.GENEBODY
SCLC-I
F
chr3: 181444409-
N_Shelf







181445000


cg18512948
chr14: 24641706
REC8.EXON1
SCLC-I
R
chr14: 24641053-
Island







24642220


cg19506253
chr2: 158301839
CYTIP.TSS1500
SCLC-I
F


cg19702383
chr12: 97885575
RMST.GENEBODY
SCLC-I
F


cg19799744
chr6: 46138963
ENPP5.TSS1500
SCLC-I
R


cg19924334
chr20: 62197682
PRIC285.GENEBODY
SCLC-I
F
chr20: 62193966-
Island







62198985


cg20716515
chr19: 44172263
PLAUR.GENEBODY
SCLC-I
F
chr19: 44172916-
N_Shore







44173252


cg21389753
chr17: 59480674
TBX2.GENEBODY
SCLC-I
F
chr17: 59473060-
Island







59483266


cg22881677
chr12: 63195695
PPM1H.GENEBODY
SCLC-I
R
chr12: 63195657-
Island







63195909


cg24743778
chr2: 220379058
ACCN4.UTR5
SCLC-I
R
chr2: 220377743-
S_Shore







220377946


cg25242557
chr11: 31833264
PAX6.TSS1500
SCLC-I
R
chr11: 31831620-
Island







31839038


cg25540824
chr6: 30139686
TRIM15.GENEBODY
SCLC-I
F
chr6: 30139718-
N_Shore







30140263


cg25587092
chr6: 32076906
TNXB.UTR5
SCLC-I
R


cg27125631
chr17: 47654653
NXPH3.GENEBODY
SCLC-I
F
chr17: 47652789-
S_Shore







47653078


cg00936309
chr6: 33141824
COL11A2.GENEBODY
SCLC-I
F


cg01116568
chr11: 10476529
AMPD3.TSS200
SCLC-I
R
chr11: 10472000-
S_Shelf







10472857


cg01594262
chr19: 38806145
YIF1B.GENEBODY
SCLC-I
R
chr19: 38806485-
N_Shore







38806747


cg02355653
chr6: 29710830
LOC285830.GENEBODY
SCLC-I
R


cg02452416
chr6: 33160450
COL11A2.TSS1500
SCLC-I
R
chr6: 33160945-
N_Shore







33161337


cg03054529
chr7: 30029938
SCRN1.TSS1500
SCLC-I
F
chr7: 30028518-
S_Shore







30029822


cg04138361
chr6: 33160304
COL11A2.TSS200
SCLC-I
F
chr6: 33160945-
N_Shore







33161337


cg04403415
chr12: 124991087
NCOR2.UTR5
SCLC-I
F


cg07387813
chr3: 40499408
RPL14.GENEBODY
SCLC-I
R
chr3: 40498639-
S_Shore







40499260


cg08858649
chr6: 30139903
TRIM15.GENEBODY
SCLC-I
R
chr6: 30139718-
Island







30140263


cg09537107
chr19: 48897008
GRIN2D.TSS1500
SCLC-I
F
chr19: 48896890-
Island







48897199


cg12049787
chr19: 45409080
APOE.EXON1
SCLC-I
R
chr19: 45411720-
N_Shelf







45412600


cg12077433
chr3: 159600838
SCHIP1.GENEBODY
SCLC-I
F


cg12108912
chr2: 120435949
TMEM177.TSS1500
SCLC-I
R
chr2: 120436530-
N_Shore







120437010


cg12643732
chr5: 691580
TPPP.UTR5
SCLC-I
F
chr5: 692681-694377
N_Shore


cg12776156
chr11: 848044
TSPAN4.UTR5
SCLC-I
F
chr11: 849087-850982
N_Shore


cg13212283
chr12: 57632120
NDUFA4L2.UTR5
SCLC-I
F
chr12: 57631932-
Island







57634578


cg14507088
chr9: 130690399
PIP5KL1.GENEBODY
SCLC-I
R
chr9: 130689378-
S_Shore







130690215


cg15622556
chr1: 12251820
TNFRSF1B.GENEBODY
SCLC-I
F
chr1: 12251777-
Island







12251985


cg16458153
chr6: 33160192
COL11A2.UTR5
SCLC-I
R
chr6: 33159991-
Island







33160263


cg16523839
chr19: 10077134
COL5A3.GENEBODY
SCLC-I
R
chr19: 10077031-
Island







10077444


cg16825133
chr19: 675672
FSTL3.TSS1500
SCLC-I
R
chr19: 675671-675881
Island


cg16860712
chr19: 48244461
EHD2.GENEBODY
SCLC-I
F
chr19: 48244150-
Island







48244693


cg18636319
chr4: 26492206
CCKAR.TSS200
SCLC-I
R


cg18788725
chr19: 45512122
RELB.GENEBODY
SCLC-I
R
chr19: 45515163-
N_Shelf







45515560


cg19776793
chr17: 79225974
SLC38A10.GENEBODY
SCLC-I
F


cg20333836
chr1: 156215418
PAQR6.GENEBODY
SCLC-I
R
chr1: 156215368-
Island







156215899


cg20639396
chr6: 128839906
PTPRK.GENEBODY
SCLC-I
R
chr6: 128840158-
N_Shore







128842126


cg20672284
chr12: 23998921
SOX5.GENEBODY
SCLC-I
R


cg21009420
chr7: 146484504
CNTNAP2.GENEBODY
SCLC-I
R


cg23337031
chr2: 236416064
AGAP1.GENEBODY
SCLC-I
F


cg23627353
chr8: 102669360
GRHL2.GENEBODY
SCLC-I
F


cg26674800
chr17: 7108653
DLG4.GENEBODY
SCLC-I
F
chr17: 7108304-7108654
Island


cg26853536
chr12: 125399964
UBC.TSS1500
SCLC-I
F
chr12: 125398558-
S_Shore







125399899


cg00126034
chr17: 44896162
WNT3.TSS200
SCLC-I
F
chr17: 44895800-
Island







44897025


cg00758881
chr16: 58534681
NDRG4.GENEBODY
SCLC-I
R
chr16: 58535040-
N_Shore







58535596


cg01029347
chr14: 77606335
ZDHHC22.UTR5
SCLC-I
R
chr14: 77605885-
Island







77608304


cg02010738
chr19: 2095466
C19orf36.TSS1500
SCLC-I
R
chr19: 2095395-2095727
Island


cg03300078
chr11: 1769522
HCCA2.GENEBODY
SCLC-I
F
chr11: 1768979-1770712
Island


cg04663692
chr12: 97885669
RMST.GENEBODY
SCLC-I
R


cg04694991
chr10: 97219665
SORBS1.UTR5
SCLC-I
F


cg06998765
chr14: 75389618
RPS6KL1.TSS1500
SCLC-I
F
chr14: 75389712-
N_Shore







75390133


cg07304692
chr2: 100939045
LONRF2.UTR5
SCLC-I
R
chr2: 100937779-
Island







100939059


cg07775371
chr16: 1922155
C16orf73.UTR5
SCLC-I
F
chr16: 1921897-1922426
Island


cg09271709
chr2: 50863603
NRXN1.GENEBODY
SCLC-I
R


cg09327981
chr7: 95455393
DYNC111.GENEBODY
SCLC-I
F


cg09750510
chr6: 25761690
SLC17A4.UTR5
SCLC-I
R


cg10098010
chr6: 138483709
KIAA1244.GENEBODY
SCLC-I
F
chr6: 138482534-
Island







138483710


cg10599438
chr19: 844589
PRTN3.GENEBODY
SCLC-I
F
chr19: 846011-846435
N_Shore


cg11565299
chr6: 30139478
TRIM15.GENEBODY
SCLC-I
F
chr6: 30139718-
N_Shore







30140263


cg11775828
chr2: 169100915
STK39.GENEBODY
SCLC-I
F
chr2: 169102950-
N_Shelf







169104454


cg12281657
chr14: 65016595
C14orf50.TSS200
SCLC-I
R
chr14: 65016516-
Island







65016909


cg12317456
chr16: 55512868
MMP2.TSS1500
SCLC-I
R
chr16: 55513220-
N_Shore







55513526


cg12699599
chr15: 40643142
PHGR1.TSS200
SCLC-I
R


cg12934382
chr3: 51741135
GRM2.EXON1
SCLC-I
F
chr3: 51740740-
Island







51741413


cg13313836
chr15: 60687284
ANXA2.UTR5
SCLC-I
R
chr15: 60689749-
N_Shelf







60690430


cg14307471
chr18: 31432117
NOL4.UTR3
SCLC-I
F


cg15174248
chr5: 149669674
CAMK2A.TSS1500
SCLC-I
F


cg17176573
chr11: 120110887
POU2F3.TSS200
SCLC-I
R
chr11: 120110497-
S_Shore







120110719


cg19419650
chr19: 7929643
EVI5L.UTR3
SCLC-I
F
chr19: 7926590-7928752
S_Shore


cg19519964
chr2: 223290012
SGPP2.GENEBODY
SCLC-I
F
chr2: 223288922-
Island







223290013


cg19722656
chr6: 119669372
MAN1A1.GENEBODY
SCLC-I
R
chr6: 119669589-
N_Shore







119671424


cg20971970
chr12: 57632495
NDUFA4L2.UTR5
SCLC-I
R
chr12: 57631932-
Island







57634578


cg21492961
chr5: 90036436
GPR98.GENEBODY
SCLC-I
R


cg21759280
chr19: 6534936
TNFSF9.GENEBODY
SCLC-I
F
chr19: 6534759-6535079
Island


cg21958743
chr12: 79832188
SYT1.GENEBODY
SCLC-I
F


cg23084895
chr1: 214162854
PROX1.UTR5
SCLC-I
R
chr1: 214160798-
S_Shore







214161034


cg25746092
chr6: 31081617
PSORS1C1.TSS1500
SCLC-I
F


cg26576206
chr19: 1064938
ABCA7.GENEBODY
SCLC-I
F
chr19: 1064897-1065191
Island


cg26839863
chr10: 21814793
C10orf140.TSS200
SCLC-I
R
chr10: 21814786-
Island







21815716


cg26995690
chr13: 36346376
DCLK1.UTR3
SCLC-I
F


cg00293644
chr1: 32674341
DCDC2B.TSS1500
SCLC-I
R
chr1: 32670569-
S_Shelf







32671885


cg00407245
chr19: 55598874
EPS8L1.GENEBODY
SCLC-I
F
chr19: 55597977-
Island







55598887


cg00848007
chr12: 68553396
IFNG.EXON1
SCLC-I
F


cg00956142
chr1: 28765031
PHACTR4.GENEBODY
SCLC-I
F


cg01666490
chr8: 102984290
NCALD.UTR5
SCLC-I
R


cg01783706
chr12: 49739991
DNAJC22.TSS1500
SCLC-I
R
chr12: 49738680-
Island







49740841


cg01902845
chr1: 214170993
PROX1.GENEBODY
SCLC-I
R


cg02275396
chr19: 15554549
WIZ.GENEBODY
SCLC-I
R
chr19: 15550849-
S_Shelf







15551059


cg03186999
chr17: 7165420
CLDN7.UTR5
SCLC-I
F
chr17: 7164285-7166245
Island


cg05257528
chr19: 846179
PRTN3.GENEBODY
SCLC-I
F
chr19: 846011-846435
Island


cg06371583
chr19: 2581343
GNG7.UTR5
SCLC-I
F
chr19: 2578956-2579746
S_Shore


cg06764736
chr12: 23998997
SOX5.GENEBODY
SCLC-I
F


cg07299645
chr7: 147256263
MIR54814.TSS1500
SCLC-I
F


cg07475922
chr19: 10122694
RDH8.TSS1500
SCLC-I
R
chr19: 10120750-
S_Shore







10121231


cg08753391
chr6: 32049622
TNXB.GENEBODY
SCLC-I
R
chr6: 32046815-
S_Shelf







32047094


cg08897422
chr7: 8666902
NXPH1.GENEBODY
SCLC-I
F


cg09588360
chr2: 54785795
SPTBN1.UTR5
SCLC-I
R
chr2: 54785026-
Island







54785969


cg10357885
chr19: 10122000
COL5A3.TSS1500
SCLC-I
R
chr19: 10120750-
S_Shore







10121231


cg11289677
chr6: 32049829
TNXB.GENEBODY
SCLC-I
R
chr6: 32046815-
S_Shelf







32047094


cg11620475
chr5: 135529232
LOC389332.TSS1500
SCLC-I
R
chr5: 135527056-
S_Shore







135528978


cg11742103
chr11: 62369870
EML3.UTR3
SCLC-I
R
chr11: 62368454-
Island







62370491


cg13500113
chr2: 216947149
TMEM169.UTR5
SCLC-I
R
chr2: 216946324-
S_Shore







216946734


cg13711424
chr14: 65017091
C14orf50.GENEBODY
SCLC-I
R
chr14: 65016516-
S_Shore







65016909


cg14025053
chr8: 104153637
C8orf56.TSS200
SCLC-I
F
chr8: 104152726-
S_Shore







104153390


cg15159069
chr3: 192634089
C3orf59.GENEBODY
SCLC-I
F
chr3: 192634309-
N_Shore







192635967


cg16573136
chr12: 49740639
DNAJC22.TSS1500
SCLC-I
F
chr12: 49738680-
Island







49740841


cg16663341
chr18: 42327562
SETBP1.GENEBODY
SCLC-I
R
chr18: 42324454-
S_Shelf







42324966


cg17617491
chr19: 2607726
GNG7.UTR5
SCLC-I
R
chr19: 2607725-2607967
Island


cg17714703
chr19: 4912221
UHRF1.GENEBODY
SCLC-I
R
chr19: 4909262-4910256
S_Shore


cg18010131
chr11: 10476620
AMPD3.TSS200
SCLC-I
F
chr11: 10472000-
S_Shelf







10472857


cg18168101
chr8: 104153627
C8orf56.TSS200
SCLC-I
F
chr8: 104152726-
S_Shore







104153390


cg18544974
chr3: 132842314
TMEM108.UTR5
SCLC-I
R


cg18716083
chr5: 111506418
EPB41L4A.GENEBODY
SCLC-I
F


cg19132462
chr11: 10476608
AMPD3.TSS200
SCLC-I
R
chr11: 10472000-
S_Shelf







10472857


cg19776942
chr1: 32714164
FAM167B.GENEBODY
SCLC-I
F
chr1: 32713918-
Island







32714186


cg19865770
chr1: 221510889
LOC400804.TSS1500
SCLC-I
F


cg21171335
chr12: 122356390
WDR66.TSS200
SCLC-I
F
chr12: 122356315-
Island







122356853


cg21213853
chr3: 51741473
GRM2.UTR5
SCLC-I
F
chr3: 51740740-
S_Shore







51741413


cg21869609
chr19: 2291613
LINGO3.GENEBODY
SCLC-I
R
chr19: 2289895-2291904
Island


cg22494035
chr15: 74537819
CCDC33.GENEBODY
SCLC-I
R
chr15: 74537809-
Island







74538114


cg22699676
chr2: 171569187
LOC440925.GENEBODY
SCLC-I
R
chr2: 171569877-
N_Shore







171573904


cg23601905
chr17: 17661060
RAI
SCLC-I
F




RAI1.UTR5


cg23635599
chr19: 45281006
CBLC.TSS200
SCLC-I
F
chr19: 45281133-
N_Shore







45281355


cg23816247
chr8: 104153827
BAALC.GENEBODY
SCLC-I
F
chr8: 104152726-
S_Shore







104153390


cg24852713
chr19: 1083423
HMHA1.GENEBODY
SCLC-I
F
chr19: 1082576-1083430
Island


cg27103348
chr21: 46321529
ITGB2.GENEBODY
SCLC-I
R
chr21: 46321397-
Island







46321644


cg27273866
chr12: 23919997
SOX5.GENEBODY
SCLC-I
R


cg01337207
chr6: 32063835
TNXB.GENEBODY
SCLC-I
F
chr6: 32063533-
Island







32065044


cg02027561
chr6: 126110790
NCOA7.TSS1500
SCLC-I
R
chr6: 126111537-
N_Shore







126112480


cg03601354
chr8: 22408966
SORBS3.TSS1500
SCLC-I
F
chr8: 22408672-
Island







22409635


cg04015907
chr20: 825489
FAM110A.GENEBODY
SCLC-I
F
chr20: 825267-826276
Island


cg05830220
chr16: 87757033
KLHDC4.GENEBODY
SCLC-I
F
chr16: 87754008-
S_Shelf







87754285


cg05957504
chr5: 124014639
ZNF608.GENEBODY
SCLC-I
F


cg06198398
chr18: 44526707
KATNAL2.TSS200
SCLC-I
R
chr18: 44526866-
N_Shore







44527137


cg07312445
chr4: 40752151
NSUN7.UTR5
SCLC-I
F
chr4: 40751842-
Island







40752493


cg07524919
chr6: 32063901
TNXB.GENEBODY
SCLC-I
F
chr6: 32063533-
Island







32065044


cg10578482
chr8: 145111298
OPLAH.GENEBODY
SCLC-I
R
chr8: 145111297-
Island







145111564


cg10625931
chr12: 57632417
NDUFA4L2.UTR5
SCLC-I
R
chr12: 57631932-
Island







57634578


cg11632652
chr3: 174648902
NAALADL2.GENEBODY
SCLC-I
F


cg13788097
chr3: 62467612
CADPS.GENEBODY
SCLC-I
F


cg14188106
chr6: 32063895
TNXB.GENEBODY
SCLC-I
F
chr6: 32063533-
Island







32065044


cg15075267
chr19: 15306332
NOTCH3.GENEBODY
SCLC-I
F
chr19: 15306243-
Island







15307111


cg15857329
chr8: 144653570
C8orf73.GENEBODY
SCLC-I
F
chr8: 144653774-
N_Shore







144653976


cg16314401
chr2: 73144481
EMX1.TSS200
SCLC-I
R
chr2: 73143055-
Island







73148260


cg16924391
chr6: 29719411
IFITM4P.TSS1500
SCLC-I
F
chr6: 29720381-
N_Shore







29721101


cg16953031
chr3: 175064540
NAALADL2.GENEBODY
SCLC-I
F


cg17693604
chr19: 3046805
TLE2.UTR5
SCLC-I
F
chr19: 3047224-3047444
N_Shore


cg18612786
chr19: 45281236
CBLC.EXON1
SCLC-I
R
chr19: 45281133-
Island







45281355


cg20502039
chr7: 95804328
SLC25A13.GENEBODY
SCLC-I
F


cg23288962
chr13: 35517516
NBEA.GENEBODY
SCLC-I
R


cg23563443
chr8: 22408989
SORBS3.TSS1500
SCLC-I
F
chr8: 22408672-
Island







22409635


cg24836242
chr6: 30908579
DPCR1.TSS200
SCLC-I
F


cg24847554
chr3: 57530606
DNAH12.TSS1500
SCLC-I
F


cg27501759
chr3: 8809715
OXTR.GENEBODY
SCLC-I
F
chr3: 8808961-8811280
Island


cg00378218
chr17: 1546841
SCARF1.GENEBODY
SCLC-I
F
chr17: 1546742-1547324
Island


cg00637695
chr5: 121759771
SNCAIP.GENEBODY
SCLC-I
R


cg01101058
chr14: 70235157
SFRS5.GENEBODY
SCLC-I
F
chr14: 70233570-
S_Shore







70234668


cg01645995
chr7: 92836152
HEPACAM2.GENEBODY
SCLC-I
R


cg01664065
chr13: 102249040
ITGBL1.GENEBODY
SCLC-I
R


cg02097532
chr3: 55673955
ERC2.UTR3
SCLC-I
F


cg02105326
chr2: 239149142
HES6.TSS1500
SCLC-I
R
chr2: 239147592-
Island







239149900


cg02124724
chr21: 46875142
COL18A1.TSS1500
SCLC-I
F
chr21: 46876168-
N_Shore







46876752


cg02515354
chr7: 147256123
MIR54814.TSS1500
SCLC-I
F


cg02638523
chr2: 236548728
AGAP1.GENEBODY
SCLC-I
R


cg02754084
chr12: 72338080
TPH2.GENEBODY
SCLC-I
F


cg04657588
chr17: 72427543
GPRC5C.TSS200
SCLC-I
F
chr17: 72426783-
Island







72428977


cg05301383
chr2: 171569144
LOC440925.GENEBODY
SCLC-I
F
chr2: 171569877-
N_Shore







171573904


cg06201680
chr7: 151078646
WDR86.UTR3
SCLC-I
R
chr7: 151078462-
Island







151079536


cg07449967
chr8: 56987020
SNORD54.TSS1500
SCLC-I
R
chr8: 56986556-
Island







56987308


cg07471157
chr12: 49373263
WNT1.GENEBODY
SCLC-I
R
chr12: 49371690-
Island







49375550


cg08580631
chr2: 170220388
LRP2.TSS1500
SCLC-I
R
chr2: 170220772-
N_Shore







170221114


cg09114581
chr6: 32077103
TNXB.UTR5
SCLC-I
R


cg10289744
chr3: 271185
CHL1.UTR5
SCLC-I
R


cg10661054
chr2: 128422179
LIMS2.GENEBODY
SCLC-I
R
chr2: 128421719-
Island







128422182


cg10810657
chr5: 66203228
MAST4.GENEBODY
SCLC-I
F


cg10970409
chr3: 42543566
VIPR1.TSS1500
SCLC-I
F
chr3: 42542820-
Island







42544524


cg11316386
chr1: 247275808
C1orf229.TSS200
SCLC-I
R
chr1: 247274585-
S_Shore







247275757


cg11642377
chr7: 8480779
NXPH1.GENEBODY
SCLC-I
R
chr7: 8481974-8482762
N_Shore
















TABLE 2







Top 1000 methylation sites assoaited with the SCLC-A subtype












Methylation
Position



Relation to


Site
(GRCh 37)
Gene
Strand
CpG Island Name
CpG Island





cg20728514
chr22:44568423
PARVG.TSS1500
R




cg13429423
chr22:44568775
PARVG.TSS200
F


cg04506569
chr2:234837977
TRPM8.GENEBODY
F


cg17542751
chr22:44568725
PARVG.TSS200
R


cg12688942
chr1:19680353
CAPZB.GENEBODY
R


cg25353896
chr22:44568753
PARVG.TSS200
F


cg02911509
chr22:44568770
PARVG.TSS200
F


cg16873414
chr22:44568699
PARVG.TSS200
R


cg25901559
chr7:157585255
PTPRN2.GENEBODY
F
chr7:157586711-157587112
N_Shore


cg07639982
chr10:12555079
CAMK1D.GENEBODY
F


cg08271031
chr22:44568812
PARVG.TSS200
R


cg17622855
chr6:157982358
ZDHHC14.GENEBODY
R


cg03817675
chr7:139299053
HIPK2.GENEBODY
R


cg17252884
chr3:15369681
SH3BP5.GENEBODY
F
chr3:15373314-15374209
N_Shelf


cg07213482
chr4:89660237
FAM13A.GENEBODY
R


cg12907969
chr5:89815060
LYSMD3.GENEBODY
R


cg25694807
chr2:161329607
RBMS1.GENEBODY
F


cg00090674
chr22:50446678
IL17REL.UTR5
F
chr22:50448567-50449521
N_Shore


cg23317857
chr6:41696297
TFEB.UTR5
F


cg11201256
chr1:184403226
C1orf21.UTR5
R


cg16860004
chr8:103137229
NCALD.TSS1500
F
chr8:103135914-103136775
S_Shore


cg15892280
chr21:40180000
ETS2.UTR5
F
chr21:40177002-40178667
S_Shore


cg03568507
chr2:240153791
HDAC4.GENEBODY
F
chr2:240153476-240153792
Island


cg19437757
chr7:157697057
PTPRN2.GENEBODY
R
chr7:157695025-157695358
S_Shore


cg27550325
chr7:157915584
PTPRN2.GENEBODY
R
chr7:157918704-157919409
N_Shelf


cg27122614
chr7:157913741
PTPRN2.GENEBODY
R


cg27110054
chr8:103137274
NCALD.TSS1500
R
chr8:103135914-103136775
S_Shore


cg07572930
chr16:81527107
CMIP.GENEBODY
F


cg17479501
chr17:80806191
TBCD.GENEBODY
R


cg02161503
chr7:157955692
PTPRN2.GENEBODY
R
chr7:157956911-157957273
N_Shore


cg13287553
chr7:4784419
FOXK1.GENEBODY
F
chr7:4784820-4785058
N_Shore


cg25746499
chr2:240153778
HDAC4.GENEBODY
F
chr2:240153476-240153792
Island


cg10672201
chr12:103353320
ASCL1.UTR3
F
chr12:103351579-103352695
S_Shore


cg06043710
chr10:560371
DIP2C.GENEBODY
F


cg18966819
chr7:4784325
FOXK1.GENEBODY
R
chr7:4784820-4785058
N_Shore


cg18578954
chr6:28887247
TRIM27.GENEBODY
F
chr6:28890951-28892013
N_Shelf


cg06228260
chr7:157854729
PTPRN2.GENEBODY
R


cg03899215
chr7:157996423
PTPRN2.GENEBODY
R
chr7:157996642-157997027
N_Shore


cg08946713
chr2:191844998
STAT1.GENEBODY
F


cg18424850
chr10:132945786
TCERG1L.GENEBODY
R


cg21167502
chr14:104195666
ZFYVE21.GENEBODY
R
chr14:104193901-104194627
S_Shore


cg27119612
chr15:57491001
TCF12.GENEBODY
R


cg04921578
chr13:101143257
PCCA.GENEBODY
F


cg08277369
chr16:84538885
KIAA1609.TSS1500
F
chr16:84538884-84539115
Island


cg08448341
chr6:134324873
SLC2A12.GENEBODY
F


cg15193475
chr15:80998711
FAM108C1.GENEBODY
F


cg17468616
chr1:226013212
EPHX1.EXON1
F


cg18730511
chr22:50435413
IL17REL.UTR3
F
chr22:50438257-50438776
N_Shelf


cg26239495
chr11:122791447
C11orf63.GENEBODY
R


cg01441025
chr8:103136942
NCALD.EXON1
F
chr8:103135914-103136775
S_Shore


cg15577272
chr7:157932397
PTPRN2.GENEBODY
F


cg21373996
chr10:560669
DIP2C.GENEBODY
R


cg06650067
chr15:66084924
DENND4A.TSS1500
R
chr15:66083839-66084925
Island


cg08951403
chr7:157960420
PTPRN2.GENEBODY
F
chr7:157956911-157957273
S_Shelf


cg09500207
chr11:68249304
SAPS3.UTR5
R


cg16896647
chr9:93563776
SYK.TSS1500
R
chr9:93563775-93564546
Island


cg10227678
chr16:54096340
FTO.GENEBODY
F


cg18883682
chr7:36655667
AOAH.GENEBODY
R


cg03558805
chr7:73184883
CLDN3.TSS1500
F
chr7:73183379-73185115
Island


cg03856153
chr3:61904580
PTPRG.GENEBODY
R


cg04610718
chr12:103353362
ASCL1.UTR3
F
chr12:103351579-103352695
S_Shore


cg06946543
chr13:76377366
LMO7.UTR5
F


cg09845489
chr7:157667853
PTPRN2.GENEBODY
R
chr7:157666069-157666399
S_Shore


cg10919624
chr7:158279891
PTPRN2.GENEBODY
F
chr7:158281373-158281734
N_Shore


cg00799539
chr12:103353183
ASCL1.UTR3
R
chr12:103351579-103352695
S_Shore


cg06663149
chr4:41457558
LIMCH1.GENEBODY
F


cg13656878
chr9:119048807
PAPPA.GENEBODY
F


cg14207833
chr19:18945153
UPF1.GENEBODY
F
chr19:18942432-18943127
S_Shelf


cg16762386
chr1:27240514
NR0B2.EXON1
F


cg26350286
chr8:95652691
ESRP1.TSS1500
R
chr8:95652455-95652873
Island


cg00624799
chr15:90605618
ZNF710.UTR5
R


cg03519907
chr5:154092426
LARP1.TSS200
F


cg09176199
chr1:246383021
SMYD3.GENEBODY
F


cg15192120
chr7:157626176
PTPRN2.GENEBODY
R


cg16048383
chr12:6483708
SCNN1A.GENEBODY
R


cg22550299
chr6:169654842
THBS2.TSS1500
R


cg23936766
chr1:230406371
GALNT2.GENEBODY
R


cg02390801
chr15:74528565
CCDC33.TSS200
F


cg05503433
chr19:42409117
ARHGEF1.GENEBODY
F
chr19:42408315-42408535
S_Shore


cg09259081
chr16:84538889
KIAA1609.TSS1500
F
chr16:84538884-84539115
Island


cg13547053
chr2:179184864
OSBPL6.TSS200
R


cg25037165
chr11:12824283
TEAD1.GENEBODY
R


cg01187496
chr5:167718124
WWC1.TSS1500
F
chr5:167718523-167719688
N_Shore


cg06338523
chr7:158279818
PTPRN2.GENEBODY
F
chr7:158281373-158281734
N_Shore


cg14947787
chr14:65405931
GPX2.UTR3
F


cg16311186
chr7:140114137
RAB19.GENEBODY
F


cg17176609
chr2:74135217
ACTG2.GENEBODY
R


cg19648306
chr2:179184854
OSBPL6.TSS200
R


cg19747960
chr8:11269117
C8orf12.GENEBODY
R


cg21867891
chr18:56529835
ZNF532.TSS1500
R
chr18:56530395-56531288
N_Shore


cg07124138
chr16:88683903
ZC3H18.GENEBODY
R


cg27336068
chr10:1336103
ADARB2.GENEBODY
R


cg19954227
chr7:158113303
PTPRN2.GENEBODY
F
chr7:158109334-158109594
S_Shelf


cg20802509
chr1:229764652
URB2.GENEBODY
F
chr1:229761128-229762299
S_Shelf


cg21679730
chr1:65047485
CACHD1.GENEBODY
R


cg21732383
chr6:169654692
THBS2.TSS1500
F


cg02428178
chr15:49104237
CEP152.TSS1500
R
chr15:49102731-49102938
S_Shore


cg09450352
chr7:157495481
PTPRN2.GENEBODY
R
chr7:157494510-157494739
S_Shore


cg13579752
chr5:153577937
GALNT10.GENEBODY
F


cg14647989
chr22:43824766
MPPED1.GENEBODY
R
chr22:43820887-43821136
S_Shelf


cg14667175
chr2:111623300
ACOXL.GENEBODY
F


cg19212465
chr7:157654170
PTPRN2.GENEBODY
F


cg25029446
chr7:157495282
PTPRN2.GENEBODY
F
chr7:157494510-157494739
S_Shore


cg00064840
chr7:4784485
FOXK1.GENEBODY
F
chr7:4784820-4785058
N_Shore


cg02473460
chr8:93074521
RUNX1T1.GENEBODY
R


cg10880973
chr6:157982213
ZDHHC14.GENEBODY
R


cg15046304
chr17:75205489
SEC14L1.GENEBODY
F
chr17:75209459-75209672
N_Shelf


cg22598247
chr7:157614399
PTPRN2.GENEBODY
R
chr7:157612036-157612316
S_Shelf


cg26247373
chr12:57655696
R3HDM2.GENEBODY
F


cg00911446
chr1:7520079
CAMTA1.GENEBODY
F


cg12761282
chr20:2276571
TGM3.TSS200
R


cg16645907
chr5:154092360
LARP1.TSS200
F


cg22057874
chr2:179184866
OSBPL6.TSS200
R


cg24928687
chr1:226012913
EPHX1.TSS200
R


cg00668890
chr12:6449990
TNFRSF1A.GENEBODY
R


cg02901644
chr2:234369787
DGKD.GENEBODY
R
chr2:234369786-234370099
Island


cg07696006
chr15:74528563
CCDC33.TSS200
F


cg11575295
chr7:158250911
PTPRN2.GENEBODY
F
chr7:158247888-158249312
S_Shore


cg15228639
chr15:42289939
PLA2G4E.GENEBODY
R


cg24241530
chr7:158061820
PTPRN2.GENEBODY
R
chr7:158060894-158061100
S_Shore


cg27555529
chr19:13617518
CACNA1A.TSS1500
F
chr19:13616752-13617267
S_Shore


cg08758185
chr5:150849936
SLC36A1.GENEBODY
F


cg10899175
chr2:11680144
GREB1.EXON1
F


cg15298059
chr7:157668141
PTPRN2.GENEBODY
F
chr7:157669879-157670095
N_Shore


cg18635670
chr6:26539327
HMGN4.UTR5
R
chr6:26538496-26539015
S_Shore


cg20149780
chr1:15751063
EFHD2.GENEBODY
F


cg03877767
chr2:11680057
GREB1.UTR5
F


cg10126234
chr14:104195533
ZFYVE21.GENEBODY
R
chr14:104193901-104194627
S_Shore


cg11035519
chr11:130051458
ST14.GENEBODY
F


cg11281961
chr2:97498902
CNNM3.UTR3
R


cg12098949
chr17:75367442
SEPT9.UTR5
F
chr17:75368688-75370506
N_Shore


cg18738906
chr12:6483739
SCNN1A.GENEBODY
R


cg24034277
chr14:102467421
DYNC1H1.GENEBODY
F


cg25264630
chr7:157849744
PTPRN2.GENEBODY
F


cg26849830
chr12:109178373
SSH1.UTR3
R


cg06221087
chr1:164659666
PBX1.GENEBODY
F


cg06694040
chr11:11301699
GALNTL4.GENEBODY
F


cg07875069
chr7:129985025
CPA5.EXON1
R


cg19308132
chr8:103137173
NCALD.TSS1500
F
chr8:103135914-103136775
S_Shore


cg19897017
chr7:2163380
MAD1L1.GENEBODY
F


cg27655671
chr6:38207741
BTBD9.GENEBODY
F


cg05800761
chr18:56529852
ZNF532.TSS1500
F
chr18:56530395-56531288
N_Shore


cg20371765
chr7:8302271
ICA1.TSS200
F
chr7:8301031-8302252
S_Shore


cg02716952
chr7:148504681
EZH2.UTR3
R


cg14592260
chr11:108798655
DDX10.GENEBODY
F


cg16937735
chr7:157562675
PTPRN2.GENEBODY
R
chr7:157560974-157561195
S_Shore


cg17208060
chr2:11680086
GREB1.EXON1
R


cg22968401
chr17:27370009
PIPOX.UTR5
F


cg23884690
chr13:113678926
MCF2L.GENEBODY
R
chr13:113676781-113677120
S_Shore


cg27431545
chr2:173607996
RAPGEF4.GENEBODY
F


cg00283887
chr7:157935557
PTPRN2.GENEBODY
F
chr7:157937614-157937841
N_Shelf


cg00773370
chr12:6483772
SCNN1A.GENEBODY
R


cg02842704
chr5:151305746
GLRA1.TSS1500
R
chr5:151304226-151304824
S_Shore


cg02865101
chr7:157779894
PTPRN2.GENEBODY
R


cg05579861
chr7:157631040
PTPRN2.GENEBODY
F
chr7:157631319-157631615
N_Shore


cg06650260
chr1:27240478
NR0B2.EXON1
R


cg07685977
chr10:133036507
TCERG1L.GENEBODY
F


cg13213923
chr17:60885491
MARCH10.UTR5
R
chr17:60885408-60885857
Island


cg19809865
chr14:44976233
FSCB.EXON1
R


cg20986887
chr6:28887284
TRIM27.GENEBODY
R
chr6:28890951-28892013
N_Shelf


cg23245485
chr12:6484219
SCNN1A.UTR5
R


cg24085344
chr17:47485676
PHB.GENEBODY
R


cg25148025
chr1:164681267
PBX1.GENEBODY
F


cg00787726
chr10:86113284
FAM190B.UTR5
F


cg03900492
chr7:157345659
PTPRN2.GENEBODY
R
chr7:157346613-157347069
N_Shore


cg04892919
chr2:191272604
MFSD6.TSS1500
R
chr2:191272484-191273671
Island


cg07942479
chr4:185747981
ACSL1.TSS1500
R
chr4:185746557-185747827
S_Shore


cg00448761
chr19:6066102
RFX2.UTR5
R


cg01792117
chr17:27088227
C17orf63.GENEBODY
F


cg02567323
chr2:48671699
KLRAQ1.GENEBODY
R
chr2:48667559-48668355
S_Shelf


cg08932665
chr11:71937515
INPPL1.GENEBODY
F
chr11:71934247-71936321
S_Shore


cg21380084
chr7:157937891
PTPRN2.GENEBODY
R
chr7:157937614-157937841
S_Shore


cg23632237
chr20:30560483
XKR7.GENEBODY
F
chr20:30555901-30556502
S_Shelf


cg25401010
chr18:56529878
ZNF532.TSS200
F
chr18:56530395-56531288
N_Shore


cg26312133
chr17:71428204
SDK2.GENEBODY
F
chr17:71431621-71431878
N_Shelf


cg01321816
chr15:91358514
BLM.UTR3
R
chr15:91362445-91362658
N_Shelf


cg03653377
chr7:158107573
PTPRN2.GENEBODY
F
chr7:158109334-158109594
N_Shore


cg24216770
chr20:35091947
DLGAP4.GENEBODY
F
chr20:35089448-35089998
S_Shore


cg25766748
chr19:13614882
CACNA1A.GENEBODY
F
chr19:13616752-13617267
N_Shore


cg26639747
chr7:157590318
PTPRN2.GENEBODY
R
chr7:157593887-157594128
N_Shelf


cg27388763
chr17:44648385
ARL17A.GENEBODY
R


cg00362322
chr16:88704230
IL17C.TSS1500
F
chr16:88706211-88706492
N_Shore


cg04874261
chr3:71773745
EIF4E3.GENEBODY
F
chr3:71773826-71774873
N_Shore


cg09130676
chr7:158220856
PTPRN2.GENEBODY
R
chr7:158217851-158220709
S_Shore


cg18011401
chr19:13617366
CACNA1A.TSS200
F
chr19:13616752-13617267
S_Shore


cg19307406
chr1:167874258
ADCY10.UTR5
R


cg19404354
chr1:202093479
GPR37L1.GENEBODY
F


cg19637113
chr15:74528522
CCDC33.TSS200
F


cg19726712
chr8:98790327
LAPTM4B.GENEBODY
F
chr8:98787835-98788874
S_Shore


cg23969274
chr6:116851736
FAM26D.UTR5
R


cg13024807
chr6:53152718
ELOVL5.GENEBODY
R


cg01100465
chr7:157585095
PTPRN2.GENEBODY
F
chr7:157586711-157587112
N_Shore


cg04373993
chr7:157570916
PTPRN2.GENEBODY
F
chr7:157568163-157568404
S_Shelf


cg05046377
chr11:4927915
OR51A7.TSS1500
F


cg06160809
chr2:217559688
IGFBP5.UTR5
F
chr2:217559039-217559484
S_Shore


cg06676049
chr2:23839842
KLHL29.GENEBODY
R


cg06912665
chr5:154092290
LARP1.TSS200
R


cg07927098
chr7:157866704
PTPRN2.GENEBODY
R


cg09644722
chr17:60885519
MARCH10.UTR5
R
chr17:60885408-60885857
Island


cg15726025
chr1:32681995
C1orf91.UTR3
F


cg19188359
chr20:2312099
TGM3.GENEBODY
R
chr20:2308778-2309042
S_Shelf


cg19890739
chr16:85723539
GINS2.TSS1500
R
chr16:85722209-85722941
S_Shore


cg23309969
chr18:56529866
ZNF532.TSS200
F
chr18:56530395-56531288
N_Shore


cg25507001
chr5:137475288
NME5.TSS200
R


cg26546155
chr16:57269635
RSPRY1.GENEBODY
F


cg01520105
chr6:111887243
TRAF3IP2.GENEBODY
R


cg04911819
chr10:24504859
KIAA1217.GENEBODY
F


cg08471739
chr3:129312902
PLXND1.GENEBODY
F


cg15120341
chr13:114238565
TFDP1.TSS1500
F


cg01277983
chr22:43835600
MPPED1.GENEBODY
F


cg01942646
chr1:27240694
NR0B2.TSS200
R


cg02639667
chr5:154092321
LARP1.TSS200
F


cg08353938
chr2:217227472
MARCH4.GENEBODY
R


cg26912251
chr6:168970824
SMOC2.GENEBODY
R
chr6:168972516-168974109
N_Shore


cg03308120
chr7:157933784
PTPRN2.GENEBODY
F
chr7:157937614-157937841
N_Shelf


cg07015608
chr7:158114303
PTPRN2.GENEBODY
R
chr7:158110569-158110881
S_Shelf


cg08698159
chr17:27294743
SEZ6.GENEBODY
R


cg08725319
chr7:157334751
PTPRN2.GENEBODY
R


cg13531977
chr9:112013420
EPB41L4B.GENEBODY
R


cg19779605
chr11:4703553
OR51E2.GENEBODY
R


cg20448594
chr7:73940352
GTF2IRD1.GENEBODY
R


cg21857959
chr3:182896995
MCF2L2.UTR3
F
chr3:182896920-182897381
Island


cg26572499
chr15:22929910
CYFIP1.GENEBODY
R


cg04198210
chr15:74528606
CCDC33.TSS200
F


cg05204104
chr2:235403141
ARL4C.UTR3
R
chr2:235404502-235406541
N_Shore


cg05822926
chr7:8302235
ICA1.TSS200
F
chr7:8301031-8302252
Island


cg18360873
chr10:133051669
TCERG1L.GENEBODY
F


cg00610577
chr12:12008666
ETV6.GENEBODY
R


cg07675656
chr16:2105015
TSC2.GENEBODY
R
chr16:2105014-2105390
Island


cg11812748
chr1:246733057
CNST.UTR5
F
chr1:246729207-246730276
S_Shelf


cg14178173
chr7:157495532
PTPRN2.GENEBODY
F
chr7:157494510-157494739
S_Shore


cg20724810
chr3:182897196
MCF2L2.GENEBODY
R
chr3:182896920-182897381
Island


cg21831937
chr15:57519802
TCF12.GENEBODY
F


cg22049038
chr7:146332766
CNTNAP2.GENEBODY
R


cg23613317
chr5:154092109
LARP1.TSS1500
R


cg24580782
chr1:27240365
NR0B2.EXON1
R


cg25975382
chr7:157532236
PTPRN2.GENEBODY
F


cg01536803
chr7:157968578
PTPRN2.GENEBODY
F


cg06070324
chr15:75322058
PPCDC.GENEBODY
R


cg06413087
chr7:157929609
PTPRN2.GENEBODY
F


cg08203715
chr11:126226154
ST3GAL4.EXON1
R
chr11:126225355-126226073
S_Shore


cg15067687
chr7:127658301
SND1.GENEBODY
F


cg15428620
chr10:102792835
SFXN3.GENEBODY
F
chr10:102790820-102791049
S_Shore


cg16681199
chr6:70990268
COL9A1.GENEBODY
R
chr6:70992040-70992912
N_Shore


cg17976873
chr14:23352295
REM2.TSS200
F
chr14:23355738-23356402
N_Shelf


cg18717689
chr9:116971578
MIR455.TSS200
R


cg25145687
chr11:1606664
HCCA2.GENEBODY
R


cg01154505
chr2:112940409
FBLN7.GENEBODY
F
chr2:112939287-112939563
S_Shore


cg03071245
chr13:37463034
SMAD9.UTR5
F


cg03527077
chr7:158059704
PTPRN2.GENEBODY
R
chr7:158060894-158061100
N_Shore


cg07979652
chr7:157934005
PTPRN2.GENEBODY
R
chr7:157937614-157937841
N_Shelf


cg09409457
chr7:157954722
PTPRN2.GENEBODY
F
chr7:157956911-157957273
N_Shelf


cg13169065
chr2:166650947
GALNT3.TSS200
F
chr2:166649909-166650966
Island


cg13619044
chr7:30202350
C7orf41.UTR3
R


cg15707428
chr2:11679845
GREB1.TSS1500
R


cg16287740
chr7:128595046
TNPO3.UTR3
R


cg19343518
chr6:157508679
ARID1B.GENEBODY
F


cg20632462
chr11:20882850
NELL1.GENEBODY
F


cg24129115
chr14:23352488
REM2.EXON1
F
chr14:23355738-23356402
N_Shelf


cg25439479
chr8:92971562
RUNX1T1.UTR3
F


cg02873384
chr11:4936857
OR51G2.EXON1
F


cg03892543
chr16:84650330
COTL1.GENEBODY
R
chr16:84650960-84651565
N_Shore


cg04466743
chr20:19915794
RIN2.GENEBODY
F


cg06424550
chr10:12808422
CAMK1D.GENEBODY
R


cg08886790
chr2:111857973
ACOXL.GENEBODY
F


cg11959316
chr1:57001742
PPAP2B.GENEBODY
R


cg16396191
chr13:42184765
KIAA0564.GENEBODY
R


cg18352935
chr11:4843021
OR51F2.EXON1
R


cg21185990
chr7:157835049
PTPRN2.GENEBODY
F


cg07056138
chr8:103120260
NCALD.UTR5
F


cg07444408
chr4:141218466
SCOC.UTR5
F


cg08871354
chr16:85723489
GINS2.TSS1500
R
chr16:85722209-85722941
S_Shore


cg09027472
chr7:157981337
PTPRN2.GENEBODY
F
chr7:157980786-157981462
Island


cg11786338
chr18:56809717
SEC11C.GENEBODY
F
chr18:56806608-56807425
S_Shelf


cg14537549
chr10:12393185
CAMK1D.GENEBODY
R
chr10:12390802-12392589
S_Shore


cg16696476
chr17:8191344
RANGRF.TSS1500
R
chr17:8191864-8192495
N_Shore


cg20239333
chr10:133111331
TCERG1L.TSS1500
F
chr10:133109193-133111052
S_Shore


cg21088119
chr8:11251471
C8orf12.GENEBODY
F


cg23758354
chr7:157434590
PTPRN2.GENEBODY
R


cg27266257
chr10:5707799
ASB13.GENEBODY
F
chr10:5707980-5708798
N_Shore


cg03345925
chr8:144599347
ZC3H3.GENEBODY
F
chr8:144601691-144601895
N_Shelf


cg07998072
chr16:19425853
TMC5.UTR5
F
chr16:19421816-19422498
S_Shelf


cg08917718
chr3:52002169
PCBP4.TSS1500
R


cg09127540
chr7:157671453
PTPRN2.GENEBODY
R
chr7:157669879-157670095
S_Shore


cg10633463
chr17:79197669
AZI1.TSS1500
R
chr17:79196345-79197419
S_Shore


cg11803278
chr7:157951799
PTPRN2.GENEBODY
F
chr7:157951254-157951800
Island


cg22797644
chr6:34206491
HMGA1.UTR5
F
chr6:34202567-34206193
S_Shore


cg22994649
chr7:157641916
PTPRN2.GENEBODY
R


cg00572756
chr7:157863106
PTPRN2.GENEBODY
R


cg02079584
chr15:74528719
CCDC33.EXON1
F


cg02111655
chr10:30338246
KIAA1462.UTR5
R


cg03332546
chr19:16553887
EPS15L1.GENEBODY
F


cg03660606
chr7:157659983
PTPRN2.GENEBODY
F
chr7:157659433-157660322
Island


cg11857514
chr12:122151762
TMEM120B.GENEBODY
F
chr12:122150513-122151091
S_Shore


cg14037240
chr10:5707981
ASB13.GENEBODY
R
chr10:5707980-5708798
Island


cg17356036
chr2:240213057
HDAC4.GENEBODY
R


cg17985311
chr1:42801965
FOXJ3.TSS1500
R
chr1:42800265-42801370
S_Shore


cg19126954
chr7:157616612
PTPRN2.GENEBODY
F
chr7:157618856-157619302
N_Shelf


cg25743482
chr11:19775505
NAV2.GENEBODY
F


cg02007867
chr7:157786536
PTPRN2.GENEBODY
R


cg06938143
chr8:11251609
C8orf12.GENEBODY
R


cg08850729
chr1:60036715
FGGY.GENEBODY
R


cg08989212
chr21:36096051
NCRNA00160.TSS200
R


cg12193099
chr6:169654018
THBS2.UTR5
R


cg12275410
chr10:135123239
ZNF511.GENEBODY
R
chr10:135123238-135123448
Island


cg12356107
chr20:22567037
FOXA2.TSS1500
R
chr20:22566821-22567055
Island


cg15252509
chr18:56337165
MALT1.TSS1500
R
chr18:56338211-56339277
N_Shore


cg16289848
chr4:79231477
FRAS1.GENEBODY
F


cg00827176
chr8:21885702
NPM2.GENEBODY
R
chr8:21882245-21882883
S_Shelf


cg01511231
chr1:1109676
TTLL10.UTR5
F
chr1:1109314-1110145
Island


cg08202399
chr16:14280512
MKL2.GENEBODY
F


cg14122506
chr9:116060914
RNF183.UTR5
R


cg16934969
chr2:173607848
RAPGEF4.GENEBODY
R


cg19755171
chr17:79197747
AZI1.TSS1500
R
chr17:79196345-79197419
S_Shore


cg20649298
chr20:22545407
C20orf56.GENEBODY
R
chr20:22548967-22549720
N_Shelf


cg22420514
chr7:157997479
PTPRN2.GENEBODY
F
chr7:157996642-157997027
S_Shore


cg23997290
chr20:22402746
LOC284788.TSS1500
F


cg27308682
chr7:157637500
PTPRN2.GENEBODY
F


cg01310118
chr6:168855168
SMOC2.GENEBODY
R


cg06155341
chr11:66048759
CNIH2.GENEBODY
R
chr11:66049750-66050229
N_Shore


cg07143635
chr16:11681487
LITAF.TSS200
F
chr16:11680008-11681275
S_Shore


cg07551677
chr8:28570561
EXTL3.UTR5
R
chr8:28573597-28573840
N_Shelf


cg13071618
chr8:144599125
ZC3H3.GENEBODY
R
chr8:144601691-144601895
N_Shelf


cg14706245
chr7:157536727
PTPRN2.GENEBODY
F


cg15175716
chr11:64120685
CCDC88B.GENEBODY
R


cg15504747
chr3:129312979
PLXND1.GENEBODY
R


cg20573218
chr3:181409863
SOX2OT.GENEBODY
F
chr3:181413014-181414022
N_Shelf


cg20825710
chr11:1620352
HCCA2.GENEBODY
R


cg23869743
chr10:99611477
GOLGA7B.GENEBODY
F
chr10:99609425-99610116
S_Shore


cg24119607
chr5:139047739
CXXC5.UTR5
F
chr5:139047905-139048235
N_Shore


cg25809301
chr3:71179811
FOXP1.GENEBODY
F


cg00781208
chr12:64433590
SRGAP1.GENEBODY
R


cg01282269
chr21:41515306
DSCAM.GENEBODY
F
chr21:41516237-41516472
N_Shore


cg02098619
chr1:8689772
RERE.GENEBODY
R


cg02704103
chr3:72846991
SHQ1.GENEBODY
R


cg02704570
chr7:157647109
PTPRN2.GENEBODY
F
chr7:157647800-157648007
N_Shore


cg04188351
chr11:33744823
CD59.UTR5
R


cg04545268
chr7:157653809
PTPRN2.GENEBODY
F


cg04583813
chr10:560323
DIP2C.GENEBODY
F


cg06287775
chr7:4784174
FOXK1.GENEBODY
R
chr7:4784820-4785058
N_Shore


cg06324554
chr7:157495841
PTPRN2.GENEBODY
R
chr7:157494510-157494739
S_Shore


cg09215582
chr4:71575507
RUFY3.GENEBODY
R
chr4:71570147-71571626
S_Shelf


cg16177693
chr1:27240669
NR0B2.TSS200
R


cg18587271
chr16:46917496
GPT2.TSS1500
F
chr16:46917849-46918957
N_Shore


cg19149693
chr3:114599007
ZBTB20.UTR5
F


cg23694187
chr7:157335188
PTPRN2.GENEBODY
F


cg23861617
chr4:83422170
TMEM150C.GENEBODY
F


cg00909926
chr1:216774208
ESRRG.GENEBODY
R
chr1:216774339-216774734
N_Shore


cg00932063
chr10:126234138
LHPP.GENEBODY
R


cg02323550
chr7:157660321
PTPRN2.GENEBODY
F
chr7:157659433-157660322
Island


cg03170878
chr7:157630174
PTPRN2.GENEBODY
F
chr7:157631319-157631615
N_Shore


cg05104995
chr10:49460249
FRMPD2.GENEBODY
F


cg05336188
chr19:18959506
UPF1.GENEBODY
F


cg05987961
chr7:158059396
PTPRN2.GENEBODY
F
chr7:158060894-158061100
N_Shore


cg11376706
chr7:157514626
PTPRN2.GENEBODY
F


cg15752885
chr7:158255389
PTPRN2.GENEBODY
F


cg19487718
chr4:185747708
ACSL1.TSS1500
R
chr4:185746557-185747827
Island


cg27282206
chr7:158179313
PTPRN2.GENEBODY
R


cg00108938
chr7:157633252
PTPRN2.GENEBODY
F
chr7:157631319-157631615
S_Shore


cg11111139
chr7:157620685
PTPRN2.GENEBODY
R
chr7:157618856-157619302
S_Shore


cg03347095
chr7:158157967
PTPRN2.GENEBODY
R


cg04772948
chr20:22401407
LOC284788.TSS200
R


cg07011711
chr11:61467286
DAGLA.UTR5
R


cg07037223
chr7:157618857
PTPRN2.GENEBODY
R
chr7:157618856-157619302
Island


cg10798171
chr7:8302301
ICA1.TSS200
F
chr7:8301031-8302252
S_Shore


cg10817855
chr7:99019985
PTCD1.GENEBODY
F
chr7:99016967-99017289
S_Shelf


cg10932907
chr11:129723947
TMEM45B.GENEBODY
F


cg12030523
chr5:126984765
CTXN3.EXON1
R


cg13808071
chr2:11679872
GREB1.TSS1500
R


cg19285478
chr11:63849412
MACROD1.GENEBODY
F
chr11:63852803-63853082
N_Shelf


cg19564367
chr4:7941852
AFAP1.TSS200
F
chr4:7940563-7941853
Island


cg24324985
chr20:22566884
FOXA2.TSS1500
R
chr20:22566821-22567055
Island


cg26160008
chr12:6451035
TNFRSF1A.UTR5
R


cg05358575
chr2:26764961
OTOF.GENEBODY
F


cg11855643
chr1:184473341
C1orf21.GENEBODY
R


cg13810707
chr7:122018993
CADPS2.GENEBODY
R


cg14974147
chr3:121310923
FBXO40.TSS1500
F


cg00035220
chr7:158197980
PTPRN2.GENEBODY
F
chr7:158198545-158198907
N_Shore


cg04112626
chr4:79861272
PAQR3.TSS1500
F
chr4:79860213-79860745
S_Shore


cg04873861
chr3:12525454
TSEN2.TSS1500
F
chr3:12525749-12526346
N_Shore


cg07011231
chr2:73329813
RAB11FIP5.GENEBODY
F


cg15000071
chr3:134889493
EPHB1.GENEBODY
F


cg15090562
chr1:6534449
PLEKHG5.GENEBODY
F
chr1:6530536-6531814
S_Shelf


cg18187658
chr1:230294691
GALNT2.GENEBODY
R


cg23313445
chr11:4792272
OR51F1.TSS1500
F


cg23636833
chr7:157514822
PTPRN2.GENEBODY
F


cg26713273
chr12:11906243
ETV6.GENEBODY
R


cg01570265
chr14:70180751
KIAA0247.UTR3
R


cg03599855
chr8:119073725
EXT1.GENEBODY
R


cg04303033
chr7:157586345
PTPRN2.GENEBODY
F
chr7:157586711-157587112
N_Shore


cg05241143
chr7:157916636
PTPRN2.GENEBODY
F
chr7:157918704-157919409
N_Shelf


cg05430989
chr3:133749309
SLCO2A1.TSS1500
F
chr3:133747920-133748266
S_Shore


cg05998486
chr7:150645092
KCNH2.GENEBODY
R
chr7:150644455-150644767
S_Shore


cg14171944
chr9:126323477
DENND1A.GENEBODY
F


cg21443274
chr8:106782921
ZFPM2.GENEBODY
R


cg11717251
chr7:157589770
PTPRN2.GENEBODY
F
chr7:157586711-157587112
S_Shelf


cg25481630
chr7:157499673
PTPRN2.GENEBODY
R
chr7:157503469-157504144
N_Shelf


cg03697708
chr19:13617549
CACNA1A.TSS1500
F
chr19:13616752-13617267
S_Shore


cg04983349
chr6:80381447
SH3BGRL2.GENEBODY
R


cg08570034
chr5:175227702
CPLX2.UTR5
F
chr5:175223609-175224679
S_Shelf


cg09805271
chr11:5010562
MMP26.GENEBODY
R


cg10531355
chr5:79489249
SERINC5.GENEBODY
R


cg13649658
chr9:140680393
EHMT1.GENEBODY
F
chr9:140683120-140683774
N_Shelf


cg14779376
chr7:157341829
PTPRN2.GENEBODY
R


cg18769909
chr7:157616107
PTPRN2.GENEBODY
F
chr7:157618856-157619302
N_Shelf


cg20808813
chr7:157663646
PTPRN2.GENEBODY
F
chr7:157666069-157666399
N_Shelf


cg26562638
chr1:226130366
LEFTY2.TSS1500
F
chr1:226127112-226127695
S_Shelf


cg01863682
chr2:182545771
NEUROD1.TSS1500
R
chr2:182547873-182549177
N_Shelf


cg02573468
chr15:41224537
DLL4.GENEBODY
F
chr15:41217789-41223180
S_Shore


cg02860921
chr7:157506297
PTPRN2.GENEBODY
F
chr7:157503469-157504144
S_Shelf


cg04087039
chr7:157697459
PTPRN2.GENEBODY
R
chr7:157694387-157694661
S_Shelf


cg06455686
chr6:168971081
SMOC2.GENEBODY
F
chr6:168972516-168974109
N_Shore


cg10122877
chr4:37585361
C4orf19.TSS1500
F


cg10288307
chr7:157563602
PTPRN2.GENEBODY
R
chr7:157560974-157561195
S_Shelf


cg11261691
chr20:30914444
KIF3B.GENEBODY
R


cg13915179
chr7:158038007
PTPRN2.GENEBODY
R
chr7:158037708-158038048
Island


cg19280540
chr19:16553711
EPS15L1.GENEBODY
R


cg22053861
chr11:65318683
LTBP3.GENEBODY
R
chr11:65321225-65321823
N_Shelf


cg22705918
chr2:25518238
DNMT3A.GENEBODY
F


cg24060173
chr1:205488243
CDK18.UTR5
R


cg25001924
chr7:157919982
PTPRN2.GENEBODY
R
chr7:157918704-157919409
S_Shore


cg26816432
chr7:158165951
PTPRN2.GENEBODY
F


cg27099497
chr7:158269297
PTPRN2.GENEBODY
F


cg27324698
chr7:157916687
PTPRN2.GENEBODY
F
chr7:157918704-157919409
N_Shelf


cg01181415
chr12:16757954
LMO3.UTR5
R


cg05552035
chr8:37699239
GPR124.GENEBODY
F
chr8:37698846-37699931
Island


cg06818217
chr12:97887662
RMST.GENEBODY
R


cg08141495
chr18:31739521
NOL4.GENEBODY
F
chr18:31739047-31739522
Island


cg09643186
chr14:65409452
GPX2.EXON1
F


cg13432032
chr15:76692444
SCAPER.GENEBODY
F


cg17611686
chr20:22547532
C20orf56.GENEBODY
F
chr20:22548967-22549720
N_Shore


cg20821442
chr7:105279882
ATXN7L1.GENEBODY
F


cg24040043
chr1:207224982
YOD1.TSS1500
F
chr1:207226281-207226842
N_Shore


cg24524099
chr7:157643007
PTPRN2.GENEBODY
R


cg02546690
chr11:17834480
SERGEF.GENEBODY
R


cg02932780
chr6:31762353
VARS.GENEBODY
R
chr6:31763240-31763905
N_Shore


cg04983296
chr4:79861284
PAQR3.TSS1500
F
chr4:79860213-79860745
S_Shore


cg09367807
chr11:1577706
HCCA2.GENEBODY
R
chr11:1577705-1579091
Island


cg11199014
chr19:39798563
LRFN1.GENEBODY
R
chr19:39797786-39799250
Island


cg14468481
chr7:157561104
PTPRN2.GENEBODY
R
chr7:157560974-157561195
Island


cg21759685
chr3:46400618
CCR2.UTR3
F


cg23629187
chr8:125576109
MTSS1.GENEBODY
R


cg00341732
chr22:31479561
SMTN.GENEBODY
F
chr22:31480774-31481373
N_Shore


cg00362285
chr1:236444212
ERO1LB.GENEBODY
F
chr1:236444603-236445700
N_Shore


cg01387450
chr2:23839710
KLHL29.GENEBODY
R


cg01557792
chr14:70162755
KIAA0247.GENEBODY
F


cg07926025
chr9:14722864
CER1.TSS200
R


cg11939450
chr20:18024215
OVOL2.GENEBODY
R


cg14119936
chr11:4791012
OR51F1.EXON1
F


cg15727524
chr7:157531216
PTPRN2.GENEBODY
F


cg16615040
chr21:41516861
DSCAM.GENEBODY
R
chr21:41516237-41516472
S_Shore


cg17491449
chr4:3344154
RGS12.GENEBODY
F
chr4:3341783-3342021
S_Shelf


cg17599372
chr7:157894874
PTPRN2.GENEBODY
F
chr7:157890656-157891557
S_Shelf


cg22016731
chr1:40311142
TRIT1.GENEBODY
F


cg22792988
chr5:76376904
SNORA47.TSS1500
F
chr5:76372882-76373720
S_Shelf


cg23919844
chr13:111819481
ARHGEF7.GENEBODY
R


cg25680145
chr6:125623414
HDDC2.TSS200
F
chr6:125622704-125623117
S_Shore


cg26480662
chr7:157778593
PTPRN2.GENEBODY
R


cg26674966
chr15:22929993
CYFIP1.GENEBODY
R


cg01782132
chr16:28936054
RABEP2.GENEBODY
R
chr16:28936053-28937036
Island


cg03788215
chr18:76757841
SALL3.UTR3
F
chr18:76751939-76755549
S_Shelf


cg06899237
chr6:153353519
RGS17.GENEBODY
R


cg08278648
chr17:27503704
MYO18A.UTR5
R
chr17:27503598-27504014
Island


cg08450080
chr7:157919807
PTPRN2.GENEBODY
R
chr7:157918704-157919409
S_Shore


cg12699647
chr17:80401857
C17orf62.UTR3
R
chr17:80401644-80401858
Island


cg13917127
chr9:116932436
COL27A1.GENEBODY
F
chr9:116930004-116930368
S_Shelf


cg15578140
chr7:147718109
MIR548F3.GENEBODY
R


cg17323383
chr3:182896670
MCF2L2.UTR3
F
chr3:182896920-182897381
N_Shore


cg18284875
chr7:157777033
PTPRN2.GENEBODY
F


cg20018344
chr20:3204138
ITPA.UTR3
R


cg21733013
chr7:22359568
RAPGEF5.UTR5
R


cg23606244
chr11:4704115
OR51E2.UTR5
F


cg23808337
chr7:158267402
PTPRN2.GENEBODY
R


cg24424217
chr10:135123421
ZNF511.GENEBODY
F
chr10:135123238-135123448
Island


cg25455408
chr19:42274924
CEACAM6.UTR3
R


cg17015844
chr12:103352694
ASCL1.EXON1
F
chr12:103351579-103352695
Island


cg00574412
chr17:27892866
ABHD15.GENEBODY
F
chr17:27893086-27896078
N_Shore


cg05012972
chr7:158250129
PTPRN2.GENEBODY
R
chr7:158250128-158250497
Island


cg10801633
chr1:10579190
PEX14.GENEBODY
R


cg11623476
chr7:2566027
LFNG.GENEBODY
F
chr7:2565872-2566114
Island


cg12661624
chr7:157957646
PTPRN2.GENEBODY
F
chr7:157956911-157957273
S_Shore


cg13102244
chr7:158198569
PTPRN2.GENEBODY
R
chr7:158198545-158198907
Island


cg14527645
chr9:116977924
COL27A1.GENEBODY
F


cg14670303
chr6:169654035
THBS2.UTR5
R


cg18280382
chr11:126225996
ST3GAL4.TSS200
F
chr11:126225355-126226073
Island


cg18438823
chr11:4676365
OR51E1.UTR3
R


cg19268477
chr7:157951471
PTPRN2.GENEBODY
F
chr7:157951254-157951800
Island


cg21413492
chr6:70990226
COL9A1.GENEBODY
F
chr6:70992040-70992912
N_Shore


cg22868951
chr4:129767588
PHF17.GENEBODY
R


cg27572053
chr7:157513908
PTPRN2.GENEBODY
F


cg00161124
chr1:234366259
SLC35F3.GENEBODY
R
chr1:234367135-234367496
N_Shore


cg00973286
chr12:6451130
TNFRSF1A.UTR5
F


cg03561416
chr6:157254584
ARID1B.GENEBODY
F


cg07773582
chr16:4845285
LOC440335.TSS200
R


cg08514594
chr7:157874020
PTPRN2.GENEBODY
F


cg09046979
chr16:28333134
SBK1.UTR3
R
chr16:28331225-28332489
S_Shore


cg10055471
chr1:27240319
NR0B2.EXON1
R


cg11809826
chr6:168918901
SMOC2.GENEBODY
F
chr6:168918596-168918902
Island


cg12286857
chr7:157530016
PTPRN2.GENEBODY
F
chr7:157524157-157526741
S_Shelf


cg14495729
chr7:158283266
PTPRN2.GENEBODY
R
chr7:158282214-158283382
Island


cg15408722
chr7:157866922
PTPRN2.GENEBODY
F


cg16025118
chr12:114273678
RBM19.GENEBODY
F


cg18789624
chr7:30516742
NOD1.UTR5
F
chr7:30517987-30518610
N_Shore


cg20673767
chr7:158061805
PTPRN2.GENEBODY
R
chr7:158060894-158061100
S_Shore


cg20979979
chr4:141218072
SCOC.UTR5
R


cg22004830
chr7:157595428
PTPRN2.GENEBODY
F
chr7:157593887-157594128
S_Shore


cg24438178
chr11:64120354
CCDC88B.GENEBODY
F


cg25023666
chr21:41585021
DSCAM.GENEBODY
F


cg00235442
chr7:157408294
PTPRN2.GENEBODY
F
chr7:157409846-157410241
N_Shore


cg04435975
chr17:46683047
LOC404266.GENEBODY
F
chr17:46685244-46685449
N_Shelf


cg08462055
chr15:64944023
ZNF609.GENEBODY
R


cg09035925
chr20:19915769
RIN2.GENEBODY
R


cg13889415
chr9:116943379
COL27A1.GENEBODY
R


cg14799696
chr7:157571491
PTPRN2.GENEBODY
R
chr7:157568163-157568404
S_Shelf


cg18522715
chr7:158298958
PTPRN2.GENEBODY
F
chr7:158301266-158301610
N_Shelf


cg20139338
chr11:64120656
CCDC88B.GENEBODY
F


cg23178546
chr7:157710554
PTPRN2.GENEBODY
R


cg25613641
chr4:140587143
MGST2.EXON1
R


cg25710298
chr2:286830
FAM150B.GENEBODY
F
chr2:287353-290099
N_Shore


cg01103601
chr2:239288872
TRAF3IP1.GENEBODY
R


cg01371493
chr6:168916145
SMOC2.GENEBODY
F
chr6:168918596-168918902
N_Shelf


cg01384111
chr2:11679605
GREB1.TSS1500
F


cg02651776
chr10:27447805
MASTL.GENEBODY
F
chr10:27444133-27444494
S_Shelf


cg03021296
chr7:158060614
PTPRN2.GENEBODY
F
chr7:158060894-158061100
N_Shore


cg04750536
chr20:19915857
RIN2.GENEBODY
R


cg07399355
chr1:155163013
MUC1.TSS1500
R
chr1:155163434-155163818
N_Shore


cg08271443
chr16:4845348
LOC440335.TSS200
R


cg08515646
chr7:157394337
PTPRN2.GENEBODY
F


cg11206084
chr7:157780161
PTPRN2.GENEBODY
F


cg13178597
chr6:153405859
RGS17.UTR5
F


cg14603031
chr7:2563184
LFNG.GENEBODY
R
chr7:2563610-2564056
N_Shore


cg16848873
chr17:46682308
LOC404266.GENEBODY
F
chr17:46685244-46685449
N_Shelf


cg20146030
chr2:166650965
GALNT3.TSS200
F
chr2:166649909-166650966
Island


cg26808921
chr6:134373925
SLC2A12.TSS200
F


cg02660277
chr7:157438616
PTPRN2.GENEBODY
F
chr7:157440024-157442721
N_Shore


cg03204605
chr4:7941837
AFAP1.TSS200
F
chr4:7940563-7941853
Island


cg03637218
chr5:115209107
AP3S1.GENEBODY
F


cg06233593
chr16:337645
AXIN1.UTR3
F
chr16:335829-336034
S_Shore


cg07267845
chr7:157345566
PTPRN2.GENEBODY
R
chr7:157346613-157347069
N_Shore


cg07323947
chr10:103896068
PPRC1.GENEBODY
R
chr10:103892659-103893590
S_Shelf


cg08482167
chr6:144066847
PHACTR2.GENEBODY
R


cg08930672
chr7:157932168
PTPRN2.GENEBODY
R


cg09984136
chr6:37190074
TMEM217.UTR5
F


cg13847963
chr1:24514220
IL28RA.TSS1500
F
chr1:24513540-24514477
Island


cg14653284
chr2:11679879
GREB1.UTR5
R


cg14800014
chr5:125800764
GRAMD3.GENEBODY
R


cg16872357
chr7:157529444
PTPRN2.GENEBODY
R
chr7:157524157-157526741
S_Shelf


cg17086205
chr7:157543597
PTPRN2.GENEBODY
R


cg17284536
chr6:166891902
RPS6KA2.GENEBODY
R


cg18174678
chr1:42801761
FOXJ3.TSS1500
F
chr1:42800265-42801370
S_Shore


cg19476622
chr18:20714485
CABLES1.TSS1500
R
chr18:20714968-20717071
N_Shore


cg19871235
chr12:71552569
TSPAN8.TSS1500
F


cg23483563
chr2:163625290
KCNH7.GENEBODY
F


cg00332882
chr20:22401271
LOC284788.GENEBODY
F


cg01076708
chr11:129689897
TMEM45B.UTR5
F
chr11:129685737-129686211
S_Shelf


cg02708758
chr15:74545009
CCDC33.GENEBODY
R


cg02978297
chr1:94057587
BCAR3.GENEBODY
R


cg06579626
chr2:73495921
FBXO41.GENEBODY
R
chr2:73495920-73496910
Island


cg06998965
chr5:68710808
MARVELD2.TSS200
R
chr5:68710807-68711520
Island


cg07520608
chr2:23627401
KLHL29.UTR5
R


cg07696757
chr7:44229001
GCK.EXON1
R


cg08826152
chr17:15869607
ADORA2B.GENEBODY
R


cg09967440
chr10:127444969
C10orf137.GENEBODY
F


cg15016771
chr2:235403218
ARL4C.UTR3
R
chr2:235404502-235406541
N_Shore


cg16666708
chr19:17797733
UNC13A.GENEBODY
F
chr19:17797530-17797748
Island


cg18351607
chr10:124739543
PSTK.TSS200
R
chr10:124739792-124740292
N_Shore


cg19502457
chr14:65409354
GPX2.EXON1
R


cg20464246
chr1:216774397
ESRRG.GENEBODY
R
chr1:216774339-216774734
Island


cg00119314
chr17:48555610
RSAD1.TSS1500
F
chr17:48556004-48556509
N_Shore


cg01861131
chr16:4845708
LOC440335.GENEBODY
R


cg02356647
chr7:158102787
PTPRN2.GENEBODY
R
chr7:158103336-158103601
N_Shore


cg03391854
chr7:157961629
PTPRN2.GENEBODY
F


cg04476846
chr5:78791415
HOMER1.GENEBODY
R


cg10471944
chr7:157345246
PTPRN2.GENEBODY
F
chr7:157346613-157347069
N_Shore


cg10481560
chr11:1597444
HCCA2.GENEBODY
R
chr11:1595809-1596143
S_Shore


cg14249078
chr11:117665480
DSCAML1.GENEBODY
F
chr11:117666634-117668141
N_Shore


cg17114257
chr11:72854156
FCHSD2.TSS1500
F
chr11:72852176-72854160
Island


cg18645642
chr1:8631756
RERE.GENEBODY
R


cg19948253
chr11:65318624
LTBP3.GENEBODY
R
chr11:65321225-65321823
N_Shelf


cg23097035
chr7:28396164
CREB5.UTR5
R


cg23381267
chr14:88787370
KCNK10.GENEBODY
F
chr14:88789600-88790493
N_Shelf


cg25167574
chr4:79861398
PAQR3.TSS1500
F
chr4:79860213-79860745
S_Shore


cg25644224
chr7:158195876
PTPRN2.GENEBODY
R
chr7:158198545-158198907
N_Shelf


cg26527638
chr17:79197398
AZI1.TSS1500
R
chr17:79196345-79197419
Island


cg00405069
chr1:52455390
RAB3B.UTR5
R
chr1:52455970-52456453
N_Shore


cg03873826
chr16:68407311
SMPD3.UTR5
F
chr16:68404907-68406273
S_Shore


cg04937416
chr7:157479272
PTPRN2.GENEBODY
F
chr7:157476886-157486719
Island


cg04977856
chr14:89886941
FOXN3.UTR5
F
chr14:89882421-89884278
S_Shelf


cg11115622
chr14:65169958
PLEKHG3.TSS1500
R
chr14:65170876-65172007
N_Shore


cg16532223
chr1:6542083
PLEKHG5.UTR5
F
chr1:6545143-6545559
N_Shelf


cg17429772
chr7:158269409
PTPRN2.GENEBODY
F


cg18943033
chr6:168993309
SMOC2.GENEBODY
R


cg21240812
chr8:143483748
TSNARE1.UTR5
F
chr8:143484018-143485051
N_Shore


cg23430388
chr3:63429828
SYNPR.GENEBODY
F


cg25503804
chr11:46739832
F2.TSS1500
R


cg02694994
chr7:157612661
PTPRN2.GENEBODY
R
chr7:157612036-157612316
S_Shore


cg05212138
chr20:23063119
CD93.UTR3
R


cg07265549
chr16:27607018
KIAA0556.GENEBODY
F


cg09350411
chr7:157667935
PTPRN2.GENEBODY
R
chr7:157669879-157670095
N_Shore


cg13794807
chr4:153871752
FHDC1.GENEBODY
R


cg15374582
chr7:158250524
PTPRN2.GENEBODY
F
chr7:158247888-158249312
S_Shore


cg25014026
chr8:73735989
KCNB2.GENEBODY
F


cg27373591
chr18:70208064
CBLN2.GENEBODY
F
chr18:70208974-70211790
N_Shore


cg01008164
chr11:4825232
OR52R1.EXON1
F


cg01338378
chr7:102036355
PRKRIP1.TSS1500
F
chr7:102036470-102037017
N_Shore


cg01789980
chr5:167743144
WWC1.GENEBODY
R


cg04682791
chr6:25313030
LRRC16A.GENEBODY
F


cg13917863
chr11:4945892
OR51G1.TSS1500
F


cg16642299
chr12:7071383
MIR200C.TSS1500
F


cg21126943
chr19:42259395
CEACAM6.TSS200
F


cg21316923
chr2:121983716
TFCP2L1.GENEBODY
F
chr2:121983326-121983740
Island


cg22054191
chr19:42637630
POU2F2.TSS1500
F
chr19:42637277-42637684
Island


cg22968167
chr11:4945873
OR51G1.TSS1500
F


cg23447996
chr9:93564603
SYK.GENEBODY
R
chr9:93563775-93564546
S_Shore


cg00537335
chr7:157989340
PTPRN2.GENEBODY
R


cg05161074
chr15:42289885
PLA2G4E.GENEBODY
F


cg13068215
chr1:240286481
FMN2.GENEBODY
R


cg16670736
chr7:157777149
PTPRN2.GENEBODY
F


cg21815508
chr7:157530036
PTPRN2.GENEBODY
R
chr7:157524157-157526741
S_Shelf


cg21881338
chr12:125566189
AACS.GENEBODY
F
chr12:125569828-125570140
N_Shelf


cg22123255
chr6:30182088
TRIM26.TSS1500
F
chr6:30180933-30182187
Island


cg23087306
chr10:119294055
EMX2OS.GENEBODY
F
chr10:119293917-119297675
Island


cg00455386
chr7:140104086
RAB19.UTR5
F


cg00679546
chr17:60729882
MRC2.GENEBODY
R
chr17:60729645-60730269
Island


cg01807748
chr1:94534645
ABCA4.GENEBODY
R


cg03758241
chr9:116929797
COL27A1.GENEBODY
R
chr9:116930004-116930368
N_Shore


cg13151425
chr7:2561116
LFNG.GENEBODY
R
chr7:2558371-2559967
S_Shore


cg14415844
chr14:91884659
CCDC88C.TSS1500
F
chr14:91883672-91885367
Island


cg19513004
chr6:34206683
HMGA1.UTR5
F
chr6:34202567-34206193
S_Shore


cg20217702
chr3:134094099
AMOTL2.TSS1500
F
chr3:134092257-134093741
S_Shore


cg21279806
chr6:169654719
THBS2.TSS1500
R


cg22017213
chr4:86851225
ARHGAP24.GENEBODY
F


cg22231602
chr1:241176676
RGS7.GENEBODY
F


cg23358740
chr14:102198157
C14orf72.GENEBODY
R


cg27096172
chr7:158350433
PTPRN2.GENEBODY
R
chr7:158349387-158350091
S_Shore


cg00590039
chr6:111888683
TRAF3IP2.GENEBODY
F


cg03653855
chr5:146436093
PPP2R2B.UTR5
R


cg03775459
chr7:105278448
ATXN7L1.GENEBODY
R


cg07602073
chr1:228595680
TRIM17.UTR3
F
chr1:228593811-228594713
S_Shore


cg09682426
chr6:168901167
SMOC2.GENEBODY
F


cg10896862
chr1:161275561
MPZ.UTR3
R


cg11534680
chr2:11680020
GREB1.UTR5
R


cg14666310
chr19:42211479
CEACAM5.TSS1500
F


cg16748524
chr7:157568392
PTPRN2.GENEBODY
F
chr7:157568163-157568404
Island


cg23447239
chr7:157697628
PTPRN2.GENEBODY
F
chr7:157694387-157694661
S_Shelf


cg24996491
chr7:157535296
PTPRN2.GENEBODY
R


cg01259220
chr7:914964
C7orf20.TSS1500
F
chr7:915753-916644
N_Shore


cg01625621
chr15:34260433
AVEN.GENEBODY
R


cg02671204
chr16:84076834
SLC38A8.TSS1500
F


cg03512414
chr20:19915874
RIN2.GENEBODY
R


cg04982488
chr10:116103698
AFAP1L2.GENEBODY
F


cg06612016
chr7:158113184
PTPRN2.GENEBODY
R
chr7:158109334-158109594
S_Shelf


cg07543823
chr22:20254968
RTN4R.GENEBODY
R
chr22:20254889-20255692
Island


cg09985802
chr10:126234119
LHPP.GENEBODY
R


cg12057576
chr15:78918529
CHRNB4.GENEBODY
R


cg12492087
chr15:42749885
ZFP106.TSS200
F


cg17772793
chr6:168901202
SMOC2.GENEBODY
R


cg19681352
chr1:27282675
C1orf172.UTR5
R
chr1:27286065-27287101
N_Shelf


cg23312425
chr11:64120623
CCDC88B.GENEBODY
F


cg25513853
chr17:72272298
DNAI2.UTR5
F
chr17:72270301-72270512
S_Shore


cg01312997
chr2:128180646
PROC.GENEBODY
R
chr2:128180294-128181381
Island


cg02641539
chr8:105351190
TM7SF4.TSS1500
R


cg04432875
chr13:113411561
ATP11A.GENEBODY
R
chr13:113410004-113410362
S_Shore


cg06626786
chr21:36094858
NCRNA00160.TSS1500
R


cg06977987
chr11:4902464
OR51T1.TSS1500
R


cg07926178
chr7:158130463
PTPRN2.GENEBODY
R


cg09001440
chr16:87952767
CA5A.GENEBODY
F


cg10926554
chr6:111888540
TRAF3IP2.GENEBODY
R


cg11863717
chr10:73725041
CHST3.UTR5
R
chr10:73723711-73724770
S_Shore


cg12109740
chr11:72084034
CLPB.GENEBODY
R


cg13427810
chr9:116990636
COL27A1.GENEBODY
F


cg23234179
chr12:88420834
C12orf50.UTR5
R


cg23520574
chr11:4928572
OR51A7.TSS200
R


cg21756355
chr7:2233135
MAD1L1.GENEBODY
F


cg00794178
chr3:182897283
MCF2L2.GENEBODY
F
chr3:182896920-182897381
Island


cg04336561
chr7:157548939
PTPRN2.GENEBODY
F
chr7:157550547-157551025
N_Shore


cg05064223
chr7:157611269
PTPRN2.GENEBODY
R
chr7:157612036-157612316
N_Shore


cg07047280
chr21:41516394
DSCAM.GENEBODY
F
chr21:41516237-41516472
Island


cg07099407
chr6:43027930
KLC4.TSS1500
R
chr6:43026939-43027841
S_Shore


cg07576632
chr6:168844079
SMOC2.GENEBODY
R
chr6:168841818-168843100
S_Shore


cg07865091
chr1:43814306
MPL.GENEBODY
R
chr1:43814305-43815277
Island


cg12510724
chr12:6484607
SCNN1A.GENEBODY
F


cg13049992
chr5:125800778
GRAMD3.GENEBODY
F


cg17027260
chr2:109892050
SH3RF3.GENEBODY
R


cg19713567
chr17:37895429
GRB7.UTR5
F


cg21850830
chr8:124553593
FBXO32.TSS200
R
chr8:124552539-124554017
Island


cg22139166
chr5:124071107
ZNF608.GENEBODY
F


cg22211507
chr3:108564871
TRAT1.GENEBODY
F


cg22676000
chr19:42259081
CEACAM6.TSS1500
F


cg22862420
chr6:153368919
RGS17.UTR5
R


cg25098281
chr12:6484713
SCNN1A.GENEBODY
F


cg25735076
chr7:158157881
PTPRN2.GENEBODY
R


cg26265390
chr6:168867606
SMOC2.GENEBODY
F


cg26308909
chr7:2233090
MAD1L1.GENEBODY
F


cg12487162
chr11:12845864
TEAD1.GENEBODY
R


cg00467296
chr11:4928760
OR51A7.EXON1
R


cg00751271
chr21:36095899
NCRNA00160.TSS1500
R


cg03521982
chr18:70206471
CBLN2.GENEBODY
F
chr18:70208974-70211790
N_Shelf


cg05004506
chr11:4945422
OR51G1.EXON1
F


cg07157169
chr5:126984994
CTXN3.EXON1
F


cg08867933
chr15:89150842
MIR1179.TSS1500
F
chr15:89147660-89149198
S_Shore


cg12812834
chr11:4870255
OR51S1.EXON1
F


cg17898069
chr1:234445489
SLC35F3.GENEBODY
F


cg18705776
chr10:5565829
CALML3.TSS1500
R
chr10:5567122-5567828
N_Shore


cg20235871
chr7:158047359
PTPRN2.GENEBODY
F


cg20786131
chr18:20714496
CABLES1.TSS1500
F
chr18:20714968-20717071
N_Shore


cg23181133
chr19:42300812
CEACAM3.GENEBODY
F


cg26169081
chr10:12648338
CAMK1D.GENEBODY
R


cg26430059
chr14:89770384
FOXN3.GENEBODY
R


cg00172803
chr16:84076941
SLC38A8.TSS1500
R


cg00832555
chr3:169529716
LRRC34.GENEBODY
F
chr3:169529875-169530435
N_Shore


cg06656027
chr12:50016493
PRPF40B.TSS1500
R
chr12:50016973-50017466
N_Shore


cg07160163
chr9:93563778
SYK.TSS1500
R
chr9:93563775-93564546
Island


cg08692006
chr19:4639992
TNFAIP8L1.TSS200
F
chr19:4639218-4639750
S_Shore


cg11028923
chr5:43557644
PAIP1.TSS1500
R
chr5:43556419-43557603
S_Shore


cg12364943
chr10:134108614
STK32C.GENEBODY
F


cg14199629
chr9:84202866
TLE1.GENEBODY
F


cg16063747
chr10:119294173
EMX2OS.GENEBODY
R
chr10:119293917-119297675
Island


cg20443278
chr17:77962098
TBC1D16.GENEBODY
R
chr17:77965805-77966296
N_Shelf


cg21436938
chr9:116061416
RNF183.TSS200
F


cg23235971
chr7:157413057
PTPRN2.GENEBODY
F
chr7:157413901-157414146
N_Shore


cg23361275
chr8:8749919
MFHAS1.EXON1
R
chr8:8748652-8751478
Island


cg24186774
chr14:63757917
RHOJ.UTR3
F


cg25223634
chr10:104536695
C10orf26.GENEBODY
R


cg00283524
chr22:44639906
KIAA1644.UTR3
F


cg01582616
chr7:157595153
PTPRN2.GENEBODY
R
chr7:157593887-157594128
S_Shore


cg04593696
chr16:84076900
SLC38A8.TSS1500
F


cg05233289
chr11:64120728
CCDC88B.GENEBODY
R


cg06721096
chr7:157336864
PTPRN2.GENEBODY
F


cg08006727
chr9:116061614
RNF183.TSS1500
R


cg10173620
chr15:89658904
ABHD2.UTR5
R


cg14638988
chr11:62476544
BSCL2.TSS1500
F
chr11:62476770-62477481
N_Shore


cg16288617
chr8:61190272
CA8.GENEBODY
F
chr8:61193312-61194195
N_Shelf


cg16347213
chr21:42687940
FAM3B.TSS1500
F
chr21:42688746-42689085
N_Shore


cg17801546
chr1:167090974
DUSP27.GENEBODY
R
chr1:167090575-167091010
Island


cg19434087
chr7:157696664
PTPRN2.GENEBODY
F
chr7:157695025-157695358
S_Shore


cg23632744
chr11:4674353
OR51E1.GENEBODY
R


cg25641451
chr11:4976263
OR51A2.EXON1
F


cg00648955
chr2:31456217
EHD3.TSS1500
R
chr2:31456740-31457653
N_Shore


cg01759986
chr20:22401074
LOC284788.GENEBODY
F


cg06683080
chr15:40646549
PHGR1.GENEBODY
R
chr15:40650055-40651102
N_Shelf


cg08339915
chr7:157394582
PTPRN2.GENEBODY
F


cg08356705
chr11:68148006
LRP5.GENEBODY
R


cg09833475
chr7:157463804
PTPRN2.GENEBODY
R


cg15331500
chr22:41779351
TEF.GENEBODY
F
chr22:41777430-41778281
S_Shore


cg19138905
chr11:4902583
OR51T1.TSS1500
R


cg20083900
chr7:157624841
PTPRN2.GENEBODY
F


cg20984904
chr7:157529335
PTPRN2.GENEBODY
R
chr7:157524157-157526741
S_Shelf


cg24939194
chr7:2563611
LFNG.GENEBODY
R
chr7:2563610-2564056
Island


cg26434090
chr11:117665395
DSCAML1.GENEBODY
R
chr11:117666634-117668141
N_Shore


cg00833703
chr16:57809842
KIFC3.GENEBODY
R


cg03916382
chr7:157935049
PTPRN2.GENEBODY
R
chr7:157937614-157937841
N_Shelf


cg04057488
chr6:168920227
SMOC2.GENEBODY
R
chr6:168918596-168918902
S_Shore


cg06649856
chr7:158355003
PTPRN2.GENEBODY
R


cg09230014
chr7:157876369
PTPRN2.GENEBODY
F


cg10178498
chr3:124103021
KALRN.GENEBODY
F


cg11374256
chr8:144888445
SCRIB.GENEBODY
R
chr8:144887111-144887662
S_Shore


cg13393785
chr19:8317932
LASS4.GENEBODY
R


cg18406801
chr2:109294820
LIMS1.GENEBODY
F


cg22297710
chr8:79717861
IL7.TSS200
F
chr8:79716681-79717403
S_Shore


cg24248505
chr7:105279790
ATXN7L1.GENEBODY
R


cg26396492
chr20:19915762
RIN2.GENEBODY
R


cg09279037
chr7:158103293
PTPRN2.GENEBODY
F
chr7:158103336-158103601
N_Shore


cg16284674
chr10:135123337
ZNF511.GENEBODY
F
chr10:135123238-135123448
Island


cg01089425
chr5:10655518
ANKRD33B.UTR3
R


cg03315058
chr11:62476542
BSCL2.TSS1500
F
chr11:62476770-62477481
N_Shore


cg04713531
chr7:158197288
PTPRN2.GENEBODY
F
chr7:158198545-158198907
N_Shore


cg07285983
chr1:174844490
RABGAP1L.GENEBODY
F


cg10188797
chr17:77962048
TBC1D16.GENEBODY
F
chr17:77965805-77966296
N_Shelf


cg10825530
chr11:16023708
SOX6.GENEBODY
R


cg22209929
chr3:172394700
NCEH1.UTR5
R


cg23735602
chr3:178276672
KCNMB2.UTR5
R


cg24153714
chr10:78057958
C10orf11.GENEBODY
F


cg24576995
chr7:157854008
PTPRN2.GENEBODY
F


cg24813588
chr20:62606499
SAMD10.UTR3
R
chr20:62605261-62605463
S_Shore


cg26967186
chr7:157919649
PTPRN2.GENEBODY
F
chr7:157918704-157919409
S_Shore


cg01610165
chr5:124071029
ZNF608.GENEBODY
R


cg01083884
chr13:113641411
MCF2L.GENEBODY
R


cg08648047
chr1:11028561
C1orf127.GENEBODY
F


cg12019520
chr4:8012176
ABLIM2.GENEBODY
F


cg15061647
chr7:158249209
PTPRN2.GENEBODY
F
chr7:158247888-158249312
Island


cg17658976
chr7:158111178
PTPRN2.GENEBODY
F
chr7:158109334-158109594
S_Shore


cg22021832
chr19:42944717
CXCL17.GENEBODY
R


cg24283093
chr3:14481550
SLC6A6.UTR5
F


cg25291404
chr20:30252580
BCL2L1.UTR3
R


cg27096807
chr3:111442336
PLCXD2.UTR3
R


cg10095968
chr21:45847903
TRPM2.GENEBODY
R
chr21:45844992-45845693
S_Shelf


cg23631070
chrX:17652804
NHS.TSS1500
R


cg03079132
chr16:727212
RHBDL1.GENEBODY
R
chr16:729438-735815
N_Shelf


cg05195085
chr7:157951403
PTPRN2.GENEBODY
F
chr7:157951254-157951800
Island


cg05308556
chr7:157408770
PTPRN2.GENEBODY
F
chr7:157409846-157410241
N_Shore


cg06675455
chr11:4902491
OR51T1.TSS1500
R


cg09958065
chr10:12648526
CAMK1D.GENEBODY
R


cg10249637
chr7:157655436
PTPRN2.GENEBODY
F
chr7:157659433-157660322
N_Shelf


cg11161846
chr1:160990452
F11R.GENEBODY
R
chr1:160990718-160991225
N_Shore


cg11859489
chr15:92459058
SLCO3A1.GENEBODY
F
chr15:92459266-92459678
N_Shore


cg12817840
chr5:124070989
ZNF608.GENEBODY
F


cg16964025
chr7:157482215
PTPRN2.GENEBODY
F
chr7:157476886-157486719
Island


cg22531685
chr7:158264663
PTPRN2.GENEBODY
R


cg25541259
chr2:230576135
DNER.GENEBODY
R
chr2:230578062-230579981
N_Shore


cg00866953
chr1:15417078
KIAA1026.GENEBODY
F


cg01315919
chr20:22401404
LOC284788.TSS200
F


cg08705382
chr1:230322024
GALNT2.GENEBODY
F


cg15572489
chr7:157481091
PTPRN2.GENEBODY
R
chr7:157476886-157486719
Island


cg21759331
chr2:209352598
PTH2R.GENEBODY
R


cg05439204
chr7:157854693
PTPRN2.GENEBODY
F


cg08240778
chr11:1643787
HCCA2.GENEBODY
F


cg08845722
chr2:46041801
PRKCE.GENEBODY
F


cg09314984
chr19:5627625
SAFB.GENEBODY
R
chr19:5622248-5623712
S_Shelf


cg09353345
chr15:78918560
CHRNB4.GENEBODY
R


cg10520790
chr4:16030846
PROM1.GENEBODY
R


cg14157855
chr1:32226424
BAI2.UTR5
R
chr1:32226146-32226535
Island


cg21660130
chr1:16370243
CLCNKB.TSS200
R


cg22531371
chr1:155162756
MUC1.TSS200
F
chr1:155163434-155163818
N_Shore


cg02690968
chr11:35683923
TRIM44.TSS1500
F
chr11:35684421-35684846
N_Shore


cg03337035
chr19:42258336
CEACAM6.TSS1500
R


cg03694261
chr11:122753977
C11orf63.UTR5
F
chr11:122753386-122753951
S_Shore


cg04701181
chr11:1606344
HCCA2.GENEBODY
F


cg05327192
chr11:75133593
KLHL35.UTR3
F
chr11:75136407-75136689
N_Shelf


cg06294561
chr3:141161580
ZBTB38.GENEBODY
F


cg12149911
chr8:61194292
CA8.TSS1500
R
chr8:61193312-61194195
S_Shore


cg14651919
chr17:74075189
ZACN.TSS200
R
chr17:74070404-74073530
S_Shore


cg15221831
chr19:42408464
ARHGEF1.GENEBODY
F
chr19:42408315-42408535
Island


cg24178676
chr5:172264981
ERGIC1.GENEBODY
F
chr5:172261145-172261671
S_Shelf


cg25205321
chr13:111096339
COL4A2.GENEBODY
R


cg00234370
chr1:36021674
KIAA0319L.UTR5
F
chr1:36022680-36023834
N_Shore


cg06716730
chr17:35851459
DUSP14.UTR5
R
chr17:35849290-35850483
S_Shore


cg21521989
chr7:158269194
PTPRN2.GENEBODY
F


cg02855558
chr7:158107723
PTPRN2.GENEBODY
F
chr7:158109334-158109594
N_Shore


cg05087455
chr2:7171869
RNF144A.GENEBODY
R
chr2:7172296-7172512
N_Shore


cg05295557
chr14:36988446
NKX2-1.GENEBODY
F
chr14:36986362-36990576
Island


cg05913555
chr7:158158760
PTPRN2.GENEBODY
R


cg20313969
chr2:112939562
FBLN7.GENEBODY
F
chr2:112939287-112939563
Island


cg24611996
chr10:120353499
PRLHR.UTR3
R
chr10:120353692-120355821
N_Shore


cg00735611
chr17:37895886
GRB7.UTR5
R


cg04854917
chr10:131378330
MGMT.GENEBODY
R


cg09149842
chr20:31351091
DNMT3B.UTR5
R
chr20:31350149-31351263
Island


cg13167816
chr14:24601808
FITM1.GENEBODY
F
chr14:24601498-24601700
S_Shore


cg14753321
chr5:176784914
RGS14.UTR5
F


cg15736062
chr7:158136485
PTPRN2.GENEBODY
R


cg15978565
chr2:11894464
LPIN1.UTR5
R


cg16809526
chr16:46917681
GPT2.TSS1500
F
chr16:46917849-46918957
N_Shore


cg17019292
chr5:68710813
MARVELD2.TSS200
R
chr5:68710807-68711520
Island


cg27270684
chr7:55757158
FKBP9L.TSS200
R


cg02711212
chr15:69854024
LOC145837.TSS200
F


cg04810063
chr16:88703634
IL17C.TSS1500
F
chr16:88706211-88706492
N_Shelf


cg06313349
chr7:157494424
PTPRN2.GENEBODY
R
chr7:157494510-157494739
N_Shore


cg11577716
chr20:20258001
C20orf26.GENEBODY
F


cg12144100
chr7:157890277
PTPRN2.GENEBODY
R
chr7:157890656-157891557
N_Shore


cg14689490
chr7:158210489
PTPRN2.GENEBODY
R


cg24634333
chr6:111887834
TRAF3IP2.GENEBODY
R


cg07780818
chr3:133749284
SLCO2A1.TSS1500
R
chr3:133747920-133748266
S_Shore


cg09635395
chr4:146601470
C4orf51.EXON1
F


cg14497491
chr17:77982477
TBC1D16.GENEBODY
F
chr17:77983980-77984482
N_Shore


cg15318176
chr7:157345827
PTPRN2.GENEBODY
F
chr7:157346613-157347069
N_Shore


cg16792062
chr11:128458153
ETS1.TSS1500
R


cg19628299
chr6:168840641
SMOC2.TSS1500
F
chr6:168841438-168841699
N_Shore


cg26924822
chr4:26332763
RBPJ.GENEBODY
F


cg00542975
chr2:122392291
CLASP1.UTR5
R


cg02369113
chr7:157637560
PTPRN2.GENEBODY
R


cg04143211
chr14:91087927
TTC7B.GENEBODY
R
chr14:91087475-91087796
S_Shore


cg04489012
chr1:151812710
LOC100132111.GENEBODY
F
chr1:151810460-151811684
S_Shore


cg06497408
chr7:158046838
PTPRN2.GENEBODY
F


cg07243405
chr7:915203
C7orf20.TSS1500
R
chr7:915753-916644
N_Shore


cg15490801
chr14:30054523
PRKD1.GENEBODY
F


cg17316096
chr7:158158218
PTPRN2.GENEBODY
R


cg21790851
chr13:73634643
KLF5.GENEBODY
F
chr13:73632860-73634370
S_Shore


cg24580076
chr7:915073
C7orf20.TSS1500
F
chr7:915753-916644
N_Shore


cg25727520
chr2:37576821
QPCT.GENEBODY
R


cg26231267
chr10:12648032
CAMK1D.GENEBODY
R


cg03641492
chr6:168859954
SMOC2.GENEBODY
R


cg04162999
chr11:64120313
CCDC88B.GENEBODY
R


cg06400336
chr8:103136701
NCALD.TSS200
R
chr8:103135914-103136775
Island


cg10308629
chr7:134354803
BPGM.GENEBODY
R


cg12813108
chr7:99719912
CNPY4.GENEBODY
R


cg15906675
chr4:90171420
GPRIN3.UTR5
R


cg18214661
chr8:17471997
PDGFRL.GENEBODY
R


cg00279797
chrX:109561918
AMMECR1.UTR5
R
chrX:109560703-109561534
S_Shore


cg01138652
chr22:19973978
ARVCF.GENEBODY
F
chr22:19974274-19974756
N_Shore


cg04457354
chr6:20447442
E2F3.GENEBODY
F


cg05564438
chr11:64120286
CCDC88B.GENEBODY
R


cg14362920
chr7:157332376
PTPRN2.UTR3
R


cg23392097
chr11:4704749
OR51E2.UTR5
R


cg26379258
chr6:111888446
TRAF3IP2.GENEBODY
R


cg02753354
chr19:1074727
HMHA1.GENEBODY
R
chr19:1074726-1075071
Island


cg04955511
chr7:14801527
DGKB.GENEBODY
F


cg05093113
chr20:49200925
MIR645.TSS1500
F


cg07756135
chr4:86748944
ARHGAP24.GENEBODY
F


cg09832443
chr7:28612680
CREB5.GENEBODY
F


cg13464117
chr7:157348161
PTPRN2.GENEBODY
R
chr7:157346613-157347069
S_Shore


cg14141549
chr7:157919408
PTPRN2.GENEBODY
F
chr7:157918704-157919409
Island


cg15353612
chr4:52904965
SGCB.TSS1500
F
chr4:52904454-52904912
S_Shore


cg21191737
chr9:15306337
TTC39B.GENEBODY
F
chr9:15306722-15307386
N_Shore


cg23574281
chr2:47716
FAM110C.TSS1500
R
chr2:45510-46559
S_Shore


cg02479744
chr6:16303089
ATXN1.UTR3
R


cg02735652
chr1:32226179
BAI2.UTR5
R
chr1:32226146-32226535
Island


cg05175762
chr7:157987088
PTPRN2.GENEBODY
F


cg09614629
chr7:157985057
PTPRN2.GENEBODY
R
chr7:157980786-157981462
S_Shelf


cg10754395
chr7:158109694
PTPRN2.GENEBODY
F
chr7:158110569-158110881
N_Shore


cg11980090
chr6:30181771
TRIM26.TSS1500
R
chr6:30180933-30182187
Island


cg12419766
chr7:157620445
PTPRN2.GENEBODY
R
chr7:157618856-157619302
S_Shore


cg12882572
chr17:35851204
DUSP14.UTR5
R
chr17:35849290-35850483
S_Shore


cg22356339
chr12:103352454
ASCL1.EXON1
R
chr12:103351579-103352695
Island


cg26085804
chr11:72854242
FCHSD2.TSS1500
F
chr11:72852176-72854160
S_Shore


cg00816406
chr1:240286626
FMN2.GENEBODY
F


cg01718785
chr7:157916279
PTPRN2.GENEBODY
F
chr7:157918704-157919409
N_Shelf


cg02601893
chr22:43523016
BIK.GENEBODY
F


cg13689591
chr3:124239629
KALRN.GENEBODY
F


cg14575854
chr17:37896175
GRB7.UTR5
F


cg20208009
chr22:19974048
ARVCF.GENEBODY
F
chr22:19974274-19974756
N_Shore


cg26572392
chr10:24496943
KIAA1217.UTR5
R


cg26572992
chr19:18876246
CRTC1.GENEBODY
F
chr19:18873019-18873349
S_Shelf


cg26593067
chr7:157446092
PTPRN2.GENEBODY
R
chr7:157448240-157448566
N_Shelf


cg01760027
chrX:49832257
CLCN5.GENEBODY
R


cg13700912
chr7:1968348
MAD1L1.GENEBODY
R
chr7:1967664-1967994
S_Shore


cg14817241
chr19:4851575
PLIN3.GENEBODY
F
chr19:4851962-4852248
N_Shore


cg16872071
chr9:135997155
RALGDS.GENEBODY
F
chr9:135995969-135996954
S_Shore


cg20867746
chr11:4871813
OR51S1.TSS1500
R


cg21376148
chr17:10276260
MYH13.UTR5
R


cg01352090
chr16:4103533
ADCY9.GENEBODY
F


cg01808739
chr1:93912802
FNBP1L.TSS1500
F
chr1:93913636-93914524
N_Shore


cg07219844
chr10:135123764
ZNF511.GENEBODY
F
chr10:135121991-135122669
S_Shore


cg09526758
chr12:16758047
LMO3.UTR5
F


cg14507792
chr9:95574913
ANKRD19.GENEBODY
R
chr9:95569429-95572255
S_Shelf


cg16609181
chr19:1083007
HMHA1.GENEBODY
R
chr19:1082576-1083430
Island


cg22337375
chr7:157351042
PTPRN2.GENEBODY
R
chr7:157352995-157353232
N_Shore


cg00926318
chr20:25177340
ENTPD6.UTR5
R
chr20:25176027-25176620
S_Shore


cg02051806
chr12:86650107
MGAT4C.UTR5
R


cg10709461
chr20:22402729
LOC284788.TSS1500
F


cg12379775
chr20:62669791
NCRNA00176.GENEBODY
F
chr20:62669304-62670730
Island


cg13265740
chr6:139349120
C6orf115.TSS1500
R
chr6:139349955-139350740
N_Shore


cg14192174
chr2:29204117
FAM179A.TSS200
F


cg18856478
chr1:43814358
MPL.GENEBODY
R
chr1:43814305-43815277
Island


cg20697464
chr2:218793716
TNS1.UTR5
R


cg23637314
chr1:216774226
ESRRG.GENEBODY
F
chr1:216774339-216774734
N_Shore


cg00008819
chr4:3257791
C4orf44.UTR3
F
chr4:3254957-3255175
S_Shelf


cg00115178
chr10:12648176
CAMK1D.GENEBODY
R


cg12538248
chr8:61194072
CA8.TSS200
R
chr8:61193312-61194195
Island


cg12806381
chr1:27114177
PIGV.TSS1500
F
chr1:27114118-27114692
Island


cg21292473
chr1:181683239
CACNA1E.GENEBODY
R


cg11315900
chr7:157605970
PTPRN2.GENEBODY
R


cg22581896
chr7:4779225
FOXK1.GENEBODY
R


cg25124966
chr11:129723987
TMEM45B.GENEBODY
R


cg25718402
chr17:7165909
CLDN7.TSS200
F
chr17:7164285-7166245
Island


cg02925076
chr7:158251297
PTPRN2.GENEBODY
F
chr7:158247888-158249312
S_Shore


cg09176256
chr10:119293967
EMX2OS.GENEBODY
F
chr10:119293917-119297675
Island


cg18099070
chr7:157845265
PTPRN2.GENEBODY
R


cg26425555
chr5:16616459
FAM134B.GENEBODY
F
chr5:16616509-16617428
N_Shore


cg26532826
chr22:31003127
TCN2.TSS200
R


cg26147269
chr3:13520256
HDAC11.TSS1500
F
chr3:13520912-13521319
N_Shore


cg14632140
chr12:16758112
LMO3.UTR5
R


cg19091386
chr7:157435297
PTPRN2.GENEBODY
F


cg04657700
chr2:223535084
MOGAT1.TSS1500
F
chr2:223536122-223536565
N_Shore


cg12132731
chr1:205313575
KLHDC8A.UTR5
F
chr1:205312493-205313576
Island


cg17956079
chr11:73358572
PLEKHB1.TSS200
R


cg01731355
chr7:158103582
PTPRN2.GENEBODY
F
chr7:158103336-158103601
Island


cg05116002
chr3:58151255
FLNB.GENEBODY
R


cg05518803
chr10:124739553
PSTK.TSS200
R
chr10:124739792-124740292
N_Shore


cg12233379
chr1:151812524
LOC100132111.GENEBODY
F
chr1:151812253-151812525
Island


cg09565319
chr6:168963731
SMOC2.GENEBODY
R


cg03721064
chr7:50535834
DDC.GENEBODY
R
chr7:50535740-50535953
Island


cg18011899
chr7:158124253
PTPRN2.GENEBODY
F


cg23967873
chr10:72977537
UNC5B.GENEBODY
R
chr10:72977123-72977774
Island


cg27430662
chr1:109656708
KIAA1324.UTR5
R
chr1:109656095-109656611
S_Shore


cg00870849
chr10:94003008
CPEB3.UTR5
F
chr10:93999131-94000015
S_Shelf


cg05765011
chr16:4103225
ADCY9.GENEBODY
F


cg18104606
chr6:70990361
COL9A1.GENEBODY
R
chr6:70992040-70992912
N_Shore


cg10724947
chr15:62359485
C2CD4A.UTR5
F
chr15:62359827-62360995
N_Shore


cg12271047
chr7:157387106
PTPRN2.GENEBODY
R
chr7:157387053-157387322
Island


cg17833037
chr12:123259751
CCDC62.GENEBODY
R


cg20354580
chr3:128713146
KIAA1257.TSS200
R
chr3:128712404-128713058
S_Shore


cg09508022
chr6:168971135
SMOC2.GENEBODY
F
chr6:168972516-168974109
N_Shore


cg15744134
chr15:32933835
SCG5.TSS200
R


cg20587332
chr8:40736768
ZMAT4.UTR5
R


cg21276549
chr13:102568345
FGF14.GENEBODY
F
chr13:102568425-102569495
N_Shore


cg21390575
chr4:185747721
ACSL1.TSS1500
R
chr4:185746557-185747827
Island


cg03905369
chr2:120824615
EPB41L5.GENEBODY
F


cg09918657
chr16:14397207
MIR193B.TSS1500
R
chr16:14395604-14397075
S_Shore


cg05640721
chr15:90437833
AP3S2.TSS1500
F
chr15:90437025-90437602
S_Shore


cg06059849
chr1:109656930
KIAA1324.EXON1
F
chr1:109656095-109656611
S_Shore


cg12609243
chr3:54155240
CACNA2D3.TSS1500
R
chr3:54155239-54157025
Island


cg19744528
chr7:157553346
PTPRN2.GENEBODY
F
chr7:157550547-157551025
S_Shelf


cg22740141
chr12:129454194
GLT1D1.GENEBODY
F


cg14981313
chr1:42847055
RIMKLA.GENEBODY
R
chr1:42845978-42846988
S_Shore


cg06023257
chr11:78129396
GAB2.TSS1500
F
chr11:78127965-78129400
Island


cg06233018
chr21:41552656
DSCAM.GENEBODY
F
chr21:41554618-41554959
N_Shore


cg09306186
chr16:73081722
ZFHX3.EXON1
F
chr16:73081590-73082565
Island


cg10545682
chr1:151512625
TUFT1.TSS200
F
chr1:151512661-151513199
N_Shore


cg10769178
chr7:157876300
PTPRN2.GENEBODY
R


cg24440468
chr7:73184642
CLDN3.TSS200
R
chr7:73183379-73185115
Island


cg26824709
chr5:159740383
CCNJL.TSS1500
R
chr5:159738781-159739913
S_Shore


cg01461199
chr8:121822473
SNTB1.GENEBODY
F
chr8:121823534-121824720
N_Shore


cg03721293
chr16:90014378
DEF8.TSS1500
F
chr16:90014250-90014613
Island


cg00336946
chr13:101186274
A2LD1.TSS1500
F
chr13:101184396-101184848
S_Shore


cg02375832
chr11:62437615
C11orf48.UTR5
R
chr11:62439047-62439803
N_Shore


cg16027376
chr8:144653975
C8orf73.GENEBODY
F
chr8:144653774-144653976
Island


cg09565670
chr19:39368408
RINL.UTR5
R


cg07915206
chr15:34260555
AVEN.GENEBODY
R


cg11445764
chr5:147773164
FBXO38.UTR5
R


cg24918790
chr22:20785148
SCARF2.GENEBODY
F
chr22:20783466-20786201
Island
















TABLE 3







Top 1000 methylation sites associated with the SCLC-N subtype












Methylation
Position



Relation to


Site
(GRCh 37)
Gene
Strand
CpG Island Name
CpG Island





cg20728514
chr22:44568423
PARVG.TSS1500
R




cg04506569
chr2:234837977
TRPM8.GENEBODY
F


cg12688942
chr1:19680353
CAPZB.GENEBODY
R


cg07213482
chr4:89660237
FAM13A.GENEBODY
R


cg11201256
chr1:184403226
C1orf21.UTR5
R


cg18966819
chr7:4784325
FOXK1.GENEBODY
R
chr7:4784820-4785058
N_Shore


cg08946713
chr2:191844998
STAT1.GENEBODY
F


cg27119612
chr15:57491001
TCF12.GENEBODY
R


cg04921578
chr13:101143257
PCCA.GENEBODY
F


cg01441025
chr8:103136942
NCALD.EXON1
F
chr8:103135914-103136775
S_Shore


cg16896647
chr9:93563776
SYK.TSS1500
R
chr9:93563775-93564546
Island


cg18883682
chr7:36655667
AOAH.GENEBODY
R


cg00624799
chr15:90605618
ZNF710.UTR5
R


cg02390801
chr15:74528565
CCDC33.TSS200
F


cg16311186
chr7:140114137
RAB19.GENEBODY
F


cg19747960
chr8:11269117
C8orf12.GENEBODY
R


cg27336068
chr10:1336103
ADARB2.GENEBODY
R


cg21732383
chr6:169654692
THBS2.TSS1500
F


cg25029446
chr7:157495282
PTPRN2.GENEBODY
F
chr7:157494510-157494739
S_Shore


cg00911446
chr1:7520079
CAMTA1.GENEBODY
F


cg12761282
chr20:2276571
TGM3.TSS200
R


cg07696006
chr15:74528563
CCDC33.TSS200
F


cg11035519
chr11:130051458
ST14.GENEBODY
F


cg11281961
chr2:97498902
CNNM3.UTR3
R


cg06221087
chr1:164659666
PBX1.GENEBODY
F


cg02716952
chr7:148504681
EZH2.UTR3
R


cg25148025
chr1:164681267
PBX1.GENEBODY
F


cg24216770
chr20:35091947
DLGAP4.GENEBODY
F
chr20:35089448-35089998
S_Shore


cg19404354
chr1:202093479
GPR37L1.GENEBODY
F


cg19637113
chr15:74528522
CCDC33.TSS200
F


cg19188359
chr20:2312099
TGM3.GENEBODY
R
chr20:2308778-2309042
S_Shelf


cg19779605
chr11:4703553
OR51E2.GENEBODY
R


cg20448594
chr7:73940352
GTF2IRD1.GENEBODY
R


cg04198210
chr15:74528606
CCDC33.TSS200
F


cg06070324
chr15:75322058
PPCDC.GENEBODY
R


cg20632462
chr11:20882850
NELL1.GENEBODY
F


cg16696476
chr17:8191344
RANGRF.TSS1500
R
chr17:8191864-8192495
N_Shore


cg22797644
chr6:34206491
HMGA1.UTR5
F
chr6:34202567-34206193
S_Shore


cg02079584
chr15:74528719
CCDC33.EXON1
F


cg02902261
chr7:72991150
TBL2.GENEBODY
R
chr7:72992434-72993397
N_Shore


cg08989212
chr21:36096051
NCRNA00160.TSS200
R


cg00827176
chr8:21885702
NPM2.GENEBODY
R
chr8:21882245-21882883
S_Shelf


cg01511231
chr1:1109676
TTLL10.UTR5
F
chr1:1109314-1110145
Island


cg07143635
chr16:11681487
LITAF.TSS200
F
chr16:11680008-11681275
S_Shore


cg20573218
chr3:181409863
SOX2OT.GENEBODY
F
chr3:181413014-181414022
N_Shelf


cg20825710
chr11:1620352
HCCA2.GENEBODY
R


cg25809301
chr3:71179811
FOXP1.GENEBODY
F


cg04188351
chr11:33744823
CD59.UTR5
R


cg06287775
chr7:4784174
FOXK1.GENEBODY
R
chr7:4784820-4785058
N_Shore


cg07530194
chr17:78808450
RPTOR.GENEBODY
R


cg01431993
chr2:182542864
NEUROD1.GENEBODY
R


cg08570034
chr5:175227702
CPLX2.UTR5
F
chr5:175223609-175224679
S_Shelf


cg01863682
chr2:182545771
NEUROD1.TSS1500
R
chr2:182547873-182549177
N_Shelf


cg22705918
chr2:25518238
DNMT3A.GENEBODY
F


cg22719871
chr11:66105148
BRMS1.UTR3
R
chr11:66102024-66102279
S_Shelf


cg22792988
chr5:76376904
SNORA47.TSS1500
F
chr5:76372882-76373720
S_Shelf


cg01782132
chr16:28936054
RABEP2.GENEBODY
R
chr16:28936053-28937036
Island


cg24424217
chr10:135123421
ZNF511.GENEBODY
F
chr10:135123238-135123448
Island


cg00161124
chr1:234366259
SLC35F3.GENEBODY
R
chr1:234367135-234367496
N_Shore


cg02544257
chr16:70510663
FUK.GENEBODY
R
chr16:70507026-70507246
S_Shelf


cg07773582
chr16:4845285
LOC440335.TSS200
R


cg08335767
chr6:34206495
HMGA1.UTR5
F
chr6:34202567-34206193
S_Shore


cg07399355
chr1:155163013
MUC1.TSS1500
R
chr1:155163434-155163818
N_Shore


cg08271443
chr16:4845348
LOC440335.TSS200
R


cg18780243
chr13:32487268
EEF1DP3.GENEBODY
R


cg25430878
chr10:1257999
ADARB2.GENEBODY
R


cg09984136
chr6:37190074
TMEM217.UTR5
F


cg17284536
chr6:166891902
RPS6KA2.GENEBODY
R


cg15553397
chr1:76695186
ST6GALNAC3.GENEBODY
R


cg01861131
chr16:4845708
LOC440335.GENEBODY
R


cg05234415
chr19:38743744
PPP1R14A.GENEBODY
R
chr19:38746638-38747379
N_Shelf


cg17114257
chr11:72854156
FCHSD2.TSS1500
F
chr11:72852176-72854160
Island


cg26527638
chr17:79197398
AZI1.TSS1500
R
chr17:79196345-79197419
Island


cg16177633
chr1:232172585
DISC1.UTR3
R


cg16532223
chr1:6542083
PLEKHG5.UTR5
F
chr1:6545143-6545559
N_Shelf


cg21240812
chr8:143483748
TSNARE1.UTR5
F
chr8:143484018-143485051
N_Shore


cg25014026
chr8:73735989
KCNB2.GENEBODY
F


cg26775087
chr3:15382808
SH3BP5.EXON1
R


cg01008405
chr5:139039026
CXXC5.UTR5
F
chr5:139040819-139041028
N_Shore


cg08082862
chr16:67807580
RANBP10.GENEBODY
F


cg22123255
chr6:30182088
TRIM26.TSS1500
F
chr6:30180933-30182187
Island


cg19513004
chr6:34206683
HMGA1.UTR5
F
chr6:34202567-34206193
S_Shore


cg21279806
chr6:169654719
THBS2.TSS1500
R


cg22017213
chr4:86851225
ARHGAP24.GENEBODY
F


cg22539431
chr7:127423253
SND1.GENEBODY
R


cg02671204
chr16:84076834
SLC38A8.TSS1500
F


cg07543823
chr22:20254968
RTN4R.GENEBODY
R
chr22:20254889-20255692
Island


cg19681352
chr1:27282675
C1orf172.UTR5
R
chr1:27286065-27287101
N_Shelf


cg06626786
chr21:36094858
NCRNA00160.TSS1500
R


cg11528849
chr2:182542901
NEUROD1.GENEBODY
R


cg02964356
chr12:49883750
SPATS2.GENEBODY
R


cg11686009
chr20:2305747
TGM3.GENEBODY
R
chr20:2308778-2309042
N_Shelf


cg16826777
chr17:43376882
MAP3K14.UTR5
F


cg18705776
chr10:5565829
CALML3.TSS1500
R
chr10:5567122-5567828
N_Shore


cg20444218
chr11:73024037
ARHGEF17.GENEBODY
F
chr11:73018452-73020563
S_Shelf


cg05214130
chr12:123945990
SNRNP35.GENEBODY
F
chr12:123942639-123943001
S_Shelf


cg07160163
chr9:93563778
SYK.TSS1500
R
chr9:93563775-93564546
Island


cg12581598
chr1:202537837
PPP1R12B.GENEBODY
F


cg12551557
chr12:32308125
BICD1.GENEBODY
R


cg16347213
chr21:42687940
FAM3B.TSS1500
F
chr21:42688746-42689085
N_Shore


cg22797514
chr1:44016023
PTPRF.GENEBODY
F


cg24575128
chr3:52502445
NISCH.GENEBODY
R


cg06683080
chr15:40646549
PHGR1.GENEBODY
R
chr15:40650055-40651102
N_Shelf


cg08356705
chr11:68148006
LRP5.GENEBODY
R


cg14583225
chr17:40074010
ACLY.UTR5
R
chr17:40074291-40075380
N_Shore


cg21602520
chr18:60985380
BCL2.GENEBODY
F
chr18:60985503-60985741
N_Shore


cg00833703
chr16:57809842
KIFC3.GENEBODY
R


cg05310309
chr2:109257429
LIMS1.UTR5
F


cg24938166
chr2:70941682
ADD2.UTR5
R


cg13685679
chr17:79231688
SLC38A10.GENEBODY
F
chr17:79235486-79235751
N_Shelf


cg08102294
chr3:13063918
IQSEC1.GENEBODY
F


cg11747695
chr13:111164966
COL4A2.UTR3
F
chr13:111164284-111164547
S_Shore


cg15691129
chrX:68725815
FAM155B.EXON1
R
chrX:68723731-68726051
Island


cg00254714
chr20:2309923
TGM3.GENEBODY
R
chr20:2308778-2309042
S_Shore


cg02624246
chr12:7073264
MIR141.GENEBODY
F


cg06164804
chr2:240044389
HDAC4.GENEBODY
R
chr2:240046200-240046736
N_Shore


cg10999000
chr13:111180025
RAB20.GENEBODY
F


cg19404444
chr1:2164602
SKI.GENEBODY
R
chr1:2158212-2161173
S_Shelf


cg25003275
chr4:7940128
AFAP1.UTR5
F
chr4:7940563-7941853
N_Shore


cg08515811
chr17:77921489
TBC1D16.GENEBODY
R
chr17:77922721-77922973
N_Shore


cg09314984
chr19:5627625
SAFB.GENEBODY
R
chr19:5622248-5623712
S_Shelf


cg16717192
chr7:4265800
SDK1.GENEBODY
R


cg16537859
chrX:70440209
BCYRN1.GENEBODY
F
chrX:70444046-70444270
N_Shelf


cg22544881
chr7:130712346
FLJ43663.GENEBODY
R


cg00806680
chr6:41561085
FOXP4.GENEBODY
F
chr6:41561221-41561473
N_Shore


cg04204246
chr6:112537238
LAMA4.GENEBODY
R


cg11938455
chr6:15622032
DTNBP1.GENEBODY
R


cg13417891
chr17:35836996
TADA2A.GENEBODY
F


cg14672994
chr17:48503057
ACSF2.TSS1500
R
chr17:48503056-48503887
Island


cg23540651
chr1:89490034
GBP3.TSS1500
R


cg27470486
chr17:40073688
ACLY.UTR5
F
chr17:40074291-40075380
N_Shore


cg17959824
chr11:70391706
SHANK2.GENEBODY
F


cg21781706
chr1:6438350
ACOT7.GENEBODY
F


cg06520307
chr7:149417640
KRBA1.GENEBODY
F
chr7:149416662-149416974
S_Shore


cg07790176
chr13:92601293
GPC5.GENEBODY
R


cg17602451
chr18:60985645
BCL2.GENEBODY
R
chr18:60985503-60985741
Island


cg25871713
chr3:37823949
ITGA9.GENEBODY
R


cg01961752
chr1:1109012
TTLL10.TSS1500
R
chr1:1109314-1110145
N_Shore


cg03486974
chr16:2199702
RAB26.GENEBODY
R
chr16:2198455-2199129
S_Shore


cg03767531
chr2:182545572
NEUROD1.TSS200
F
chr2:182547873-182549177
N_Shelf


cg18470891
chr12:2986957
FOXM1.TSS1500
R
chr12:2985978-2986639
S_Shore


cg02364642
chr12:58005758
GEFT.EXON1
R
chr12:58003880-58004249
S_Shore


cg02643580
chr12:95671146
VEZT.GENEBODY
R


cg02836529
chr2:182544413
NEUROD1.UTR5
R
chr2:182547873-182549177
N_Shelf


cg03641492
chr6:168859954
SMOC2.GENEBODY
R


cg04048740
chr2:236442999
AGAP1.GENEBODY
F
chr2:236443815-236444025
N_Shore


cg10198932
chr21:43136287
C21orf129.TSS1500
F


cg10308629
chr7:134354803
BPGM.GENEBODY
R


cg17093877
chr17:72206412
MGC16275.GENEBODY
F
chr17:72208474-72208902
N_Shelf


cg04457354
chr6:20447442
E2F3.GENEBODY
F


cg22193393
chr15:42290845
PLA2G4E.GENEBODY
R


cg04531425
chr2:182322841
ITGA4.GENEBODY
F
chr2:182321761-182323029
Island


cg06979020
chr16:69660388
NFAT5.UTR5
R


cg20978600
chr3:40566157
ZNF621.TSS1500
R
chr3:40566129-40566689
Island


cg23574281
chr2:47716
FAM110C.TSS1500
R
chr2:45510-46559
S_Shore


cg00459232
chr12:6309025
CD9.TSS1500
R
chr12:6309152-6310392
N_Shore


cg05722741
chr6:168897588
SMOC2.GENEBODY
F


cg08134671
chr19:2542837
GNG7.UTR5
R
chr19:2543638-2543878
N_Shore


cg11980090
chr6:30181771
TRIM26.TSS1500
R
chr6:30180933-30182187
Island


cg18822036
chr8:131371659
ASAP1.GENEBODY
R
chr8:131370087-131371317
S_Shore


cg20535931
chr7:97615658
OCM2.GENEBODY
F


cg27567922
chr3:195480636
MUC4.GENEBODY
F
chr3:195477711-195477983
S_Shelf


cg13374528
chr7:129414627
MIR96.TSS200
R
chr7:129418286-129422509
N_Shelf


cg00690082
chr17:40438511
STAT5A.TSS1500
R
chr17:40440188-40441014
N_Shore


cg00929655
chr15:92459909
SLCO3A1.GENEBODY
R
chr15:92459266-92459678
S_Shore


cg01983725
chr1:227161799
CABC1.GENEBODY
F
chr1:227163739-227164237
N_Shore


cg02058628
chr1:2164542
SKI.GENEBODY
F
chr1:2158212-2161173
S_Shelf


cg07219844
chr10:135123764
ZNF511.GENEBODY
F
chr10:135121991-135122669
S_Shore


cg02051924
chr16:11681482
LITAF.TSS200
R
chr16:11680008-11681275
S_Shore


cg24728949
chr5:106820169
EFNA5.GENEBODY
F


cg02276086
chr2:163175335
IFIH1.TSS1500
F


cg26392737
chr8:21916853
EPB49.EXON1
F
chr8:21914275-21914525
S_Shelf


cg00797278
chr3:32442928
CMTM7.GENEBODY
F
chr3:32443152-32443455
N_Shore


cg01435515
chr1:151255742
ZNF687.UTR5
R
chr1:151253658-151255769
Island


cg02710090
chr1:207225128
PFKFB2.TSS1500
F
chr1:207226281-207226842
N_Shore


cg04633683
chr16:29837056
MVP.UTR5
R


cg04905719
chr6:134617250
SGK1.GENEBODY
F


cg09035736
chr22:38599166
MAFF.UTR5
F
chr22:38597785-38598988
S_Shore


cg09556527
chr1:1239259
ACAP3.GENEBODY
F
chr1:1242400-1245185
N_Shelf


cg05379127
chr19:12885939
HOOK2.GENEBODY
F
chr19:12885756-12886519
Island


cg26147269
chr3:13520256
HDAC11.TSS1500
F
chr3:13520912-13521319
N_Shore


cg17107112
chr6:34021546
GRM4.GENEBODY
R
chr6:34024201-34024457
N_Shelf


cg09890699
chr1:54821853
SSBP3.GENEBODY
R
chr1:54821990-54822333
N_Shore


cg14882082
chr14:100845427
WDR25.UTR5
F
chr14:100842339-100842931
S_Shelf


cg16071713
chr21:36412456
C21orf96.TSS1500
F


cg23674344
chr17:48503163
ACSF2.TSS1500
F
chr17:48503056-48503887
Island


cg00489219
chr3:40566141
ZNF621.TSS1500
F
chr3:40566129-40566689
Island


cg08230118
chr6:30181847
TRIM26.TSS1500
R
chr6:30180933-30182187
Island


cg10451262
chr8:124284176
ZHX1.UTR5
R
chr8:124286209-124287666
N_Shelf


cg16522557
chr13:111159111
COL4A2.GENEBODY
F


cg20427144
chr7:5518918
FBXL18.UTR3
F
chr7:5521368-5521615
N_Shelf


cg20806345
chr2:182543706
NEUROD1.UTR5
F


cg02185402
chr20:400361
RBCK1.GENEBODY
F
chr20:400244-400469
Island


cg07908874
chr10:135123006
ZNF511.GENEBODY
R
chr10:135122851-135123109
Island


cg21913981
chr12:120151706
MIR1178.TSS200
R


cg26363039
chr12:1609549
LOC100292680.TSS200
R


cg00870849
chr10:94003008
CPEB3.UTR5
F
chr10:93999131-94000015
S_Shelf


cg08521073
chr12:117314052
HRK.UTR3
R
chr12:117316389-117317611
N_Shelf


cg12218991
chr4:152042934
SH3D19.UTR3
F


cg14014950
chr3:64125334
PRICKLE2.GENEBODY
R


cg14220262
chr1:1114963
TTLL10.GENEBODY
F
chr1:1115574-1116006
N_Shore


cg20417351
chr17:424358
VPS53.GENEBODY
R


cg01154445
chr2:206548171
NRP2.GENEBODY
F
chr2:206549599-206551316
N_Shore


cg04569165
chrX:153688677
PLXNA3.GENEBODY
F
chrX:153688592-153688860
Island


cg04957757
chr16:70463218
ST3GAL2.UTR5
R


cg07660671
chr8:10586967
SOX7.GENEBODY
F
chr8:10587304-10591109
N_Shore


cg09354317
chr3:52869307
MUSTN1.TSS200
F


cg11484283
chr4:159816181
FNIP2.GENEBODY
F


cg19563107
chr14:53418879
FERMT2.TSS1500
R
chr14:53417108-53418339
S_Shore


cg22110158
chr11:130036542
ST14.GENEBODY
F


cg22369288
chr6:138538817
PBOV1.EXON1
R


cg02954284
chr22:21367447
MGC16703.GENEBODY
R
chr22:21368197-21368771
N_Shore


cg08059112
chr19:2294887
LINGO3.UTR5
R
chr19:2294886-2295101
Island


cg13859860
chr10:51569878
NCOA4.UTR5
F
chr10:51572198-51572620
N_Shelf


cg14666908
chr6:31937758
STK19.TSS1500
R
chr6:31939730-31940559
N_Shore


cg16404364
chr7:1006746
COX19.UTR3
F
chr7:1007159-1007558
N_Shore


cg19711579
chr2:182545562
NEUROD1.TSS200
F
chr2:182547873-182549177
N_Shelf


cg22976218
chr2:182544321
NEUROD1.UTR5
R
chr2:182547873-182549177
N_Shelf


cg03569876
chr5:148908014
CSNK1A1.GENEBODY
R


cg03674563
chr11:422260
ANO9.GENEBODY
R
chr11:420265-420975
S_Shore


cg06374811
chr6:22099667
FLJ22536.GENEBODY
R


cg19359218
chr6:30181936
TRIM26.TSS1500
R
chr6:30180933-30182187
Island


cg21163701
chr8:85165845
RALYL.UTR5
F


cg26743132
chr13:111107905
COL4A2.GENEBODY
F
chr13:111109139-111109652
N_Shore


cg19754622
chr10:134045578
STK32C.GENEBODY
F
chr10:134041499-134041784
S_Shelf


cg03769629
chr6:30181591
TRIM26.TSS1500
R
chr6:30180933-30182187
Island


cg22222281
chr12:6308758
CD9.TSS1500
R
chr12:6309152-6310392
N_Shore


cg25903363
chr8:21972479
HR.UTR3
R


cg00321901
chr8:10512459
RP1L1.EXON1
R


cg03695433
chr17:71332907
SDK2.UTR3
F


cg24408763
chr6:43446221
TJAP1.UTR5
R


cg24603926
chr12:120151679
MIR1178.TSS200
R


cg27098470
chr22:42828411
NFAM1.TSS200
R


cg02102889
chr4:139164723
SLC7A11.TSS1500
R


cg04176122
chr11:118779835
BCL9L.GENEBODY
F
chr11:118781060-118781732
N_Shore


cg15409237
chr19:51524249
KLK10.TSS1500
F
chr19:51522004-51522803
S_Shore


cg17401435
chr11:63887426
MACROD1.GENEBODY
F
chr11:63887355-63887600
Island


cg19008877
chr10:78157854
C10orf11.GENEBODY
R


cg11286977
chr6:30181713
TRIM26.TSS1500
R
chr6:30180933-30182187
Island


cg01027553
chr7:4037843
SDK1.GENEBODY
F


cg01155325
chr15:42719757
ZFP106.GENEBODY
R


cg06714480
chr2:182544307
NEUROD1.UTR5
R
chr2:182547873-182549177
N_Shelf


cg07181952
chr1:1239999
ACAP3.GENEBODY
F
chr1:1242400-1245185
N_Shelf


cg09306186
chr16:73081722
ZFHX3.EXON1
F
chr16:73081590-73082565
Island


cg20709008
chr2:182545934
NEUROD1.TSS1500
F
chr2:182547873-182549177
N_Shore


cg25356639
chr3:71349304
FOXP1.UTR5
F


cg01788682
chr3:15382723
SH3BP5.UTR5
F


cg07109923
chr20:35091317
DLGAP4.GENEBODY
R
chr20:35089448-35089998
S_Shore


cg13538006
chr9:95897313
NINJ1.TSS1500
R
chr9:95896007-95897016
S_Shore


cg13818276
chr22:32437865
SLC5A1.TSS1500
R
chr22:32439046-32439442
N_Shore


cg08530036
chr1:19496406
UBR4.GENEBODY
R


cg09388414
chr7:129414651
MIR96.TSS200
R
chr7:129418286-129422509
N_Shelf


cg18124764
chr7:101558698
CUX1.GENEBODY
F
chr7:101559402-101559625
N_Shore


cg23406864
chr22:21053952
TMEM191A.TSS1500
R
chr22:21056258-21058793
N_Shelf


cg23731742
chr1:879958
NOC2L.UTR3
R
chr1:875730-878363
S_Shore


cg00735329
chr18:74732603
MBP.GENEBODY
R


cg04757345
chr4:128918835
C4orf29.GENEBODY
F


cg19681793
chr6:169651645
THBS2.UTR5
R
chr6:169648546-169649047
S_Shelf


cg22332321
chr20:62510260
TPD52L2.GENEBODY
R
chr20:62509163-62509369
S_Shore


cg22817352
chr1:204653629
LRRN2.UTR5
F
chr1:204654132-204654885
N_Shore


cg03723730
chr6:34031694
GRM4.GENEBODY
F


cg20660385
chr19:51526587
KLK11.GENEBODY
R
chr19:51522004-51522803
S_Shelf


cg20708173
chr4:7940426
AFAP1.UTR5
R
chr4:7940563-7941853
N_Shore


cg23218957
chr14:59109856
DACT1.GENEBODY
R
chr14:59113071-59113640
N_Shelf


cg14660446
chr19:48015621
NAPA.GENEBODY
F
chr19:48017717-48018782
N_Shelf


cg19296671
chr11:128562297
FLI1.TSS200
R
chr11:128562671-128565011
N_Shore


cg02921634
chr21:43109546
NCRNA00111.GENEBODY
F
chr21:43109349-43109687
Island


cg03365751
chr22:42828386
NFAM1.EXON1
F


cg06136185
chr17:79139087
LOC388428.TSS1500
R
chr17:79139501-79140028
N_Shore


cg06963053
chr2:182545533
NEUROD1.TSS200
F
chr2:182547873-182549177
N_Shelf


cg10806639
chr13:33780078
STARD13.EXON1
R


cg20970369
chr1:111744108
DENND2D.TSS1500
F
chr1:111746337-111747303
N_Shelf


cg21244086
chr15:45479462
SHF.GENEBODY
F
chr15:45479509-45480498
N_Shore


cg10159951
chr11:35441881
SLC1A2.TSS1500
F
chr11:35440375-35441882
Island


cg10614445
chr2:25526696
DNMT3A.GENEBODY
F


cg22486214
chr17:78930466
RPTOR.GENEBODY
F


cg25043538
chr11:63887437
MACROD1.GENEBODY
R
chr11:63887355-63887600
Island


cg01670896
chr8:1933522
KBTBD11.UTR5
F


cg02959939
chr21:47813025
PCNT.GENEBODY
F
chr21:47813251-47813462
N_Shore


cg07533617
chr11:117624926
DSCAML1.GENEBODY
R


cg10143807
chr1:155050924
EFNA3.TSS1500
F
chr1:155051155-155055291
N_Shore


cg14765206
chr10:101744219
DNMBP.UTR5
R


cg21798544
chr11:924646
AP2A2.TSS1500
R
chr11:925183-926083
N_Shore


cg26142132
chr17:74463585
AANAT.TSS200
R


cg03368643
chr6:30181600
TRIM26.TSS1500
R
chr6:30180933-30182187
Island


cg07827420
chr17:75371764
SEPT9.UTR5
F
chr17:75368688-75370506
S_Shore


cg15935860
chr1:201282499
PKP1.GENEBODY
F


cg26813796
chr1:225806065
ENAH.GENEBODY
R


cg19778462
chr1:41976072
HIVEP3.UTR3
F


cg22149419
chr17:27253138
PHF12.GENEBODY
R


cg12710538
chr17:27490340
MYO18A.GENEBODY
F
chr17:27493203-27493880
N_Shelf


cg13250203
chr11:1565798
HCCA2.GENEBODY
R
chr11:1567940-1568907
N_Shelf


cg26245202
chr1:205602864
ELK4.TSS1500
F
chr1:205600493-205601432
S_Shore


cg01474011
chr2:225435131
CUL3.GENEBODY
F


cg08549332
chr7:101558461
CUX1.GENEBODY
F
chr7:101559402-101559625
N_Shore


cg16935790
chr17:77043246
C1QTNF1.GENEBODY
R
chr17:77043741-77044489
N_Shore


cg21285555
chr8:52771466
PCMTD1.GENEBODY
R


cg04956949
chr7:73119262
STX1A.GENEBODY
F
chr7:73118500-73118749
S_Shore


cg08519905
chr12:6308774
CD9.TSS1500
R
chr12:6309152-6310392
N_Shore


cg09560636
chr5:43631579
NNT.GENEBODY
R


cg12400725
chr1:29240533
EPB41.UTR5
R
chr1:29240768-29241969
N_Shore


cg19397765
chr6:30181764
TRIM26.TSS1500
R
chr6:30180933-30182187
Island


cg21585162
chr11:128566387
FLI1.GENEBODY
F
chr11:128562671-128565011
S_Shore


cg25004427
chr5:326523
AHRR.GENEBODY
R
chr5:320788-323010
S_Shelf


cg08821738
chr17:77043179
C1QTNF1.GENEBODY
F
chr17:77043741-77044489
N_Shore


cg14570838
chr11:128562353
FLI1.TSS1500
F
chr11:128562671-128565011
N_Shore


cg17397159
chr4:720144
PCGF3.UTR5
F
chr4:716281-716977
S_Shelf


cg18601229
chr15:42192297
EHD4.UTR3
R
chr15:42192913-42193255
N_Shore


cg00162859
chr8:131268256
ASAP1.GENEBODY
F


cg08162476
chr3:13064001
IQSEC1.GENEBODY
R


cg02893260
chr13:30071603
MTUS2.GENEBODY
R


cg03508204
chr2:129057540
HS6ST1.GENEBODY
F


cg04176557
chr11:75902270
WNT11.GENEBODY
R
chr11:75905717-75905918
N_Shelf


cg05230392
chr17:55976522
CUEDC1.UTR5
F


cg05912053
chr15:60919520
RORA.GENEBODY
R


cg12758867
chr11:65354231
EHBP1L1.GENEBODY
F
chr11:65352231-65353134
S_Shore


cg13889934
chr4:86851399
ARHGAP24.GENEBODY
F


cg14454073
chr14:50159754
KLHDC1.TSS200
F
chr14:50159667-50160424
Island


cg14475480
chr17:79655469
HGS.GENEBODY
R
chr17:79655162-79655515
Island


cg18041814
chr6:36802896
CPNE5.GENEBODY
F
chr6:36806881-36807217
N_Shelf


cg20735041
chr3:52869266
MUSTN1.TSS200
R


cg04658856
chr6:16242468
GMPR.GENEBODY
R
chr6:16238589-16239231
S_Shelf


cg05004108
chr1:85931167
DDAH1.TSS1500
F
chr1:85929940-85931168
Island


cg14986845
chr6:30182240
TRIM26.TSS1500
R
chr6:30180933-30182187
S_Shore


cg15742605
chr1:879383
SAMD11.GENEBODY
F
chr1:875730-878363
S_Shore


cg20894936
chr11:1630266
HCCA2.GENEBODY
F


cg23417096
chr8:134250016
NDRG1.UTR3
R


cg27104413
chr3:101044447
SENP7.UTR3
R


cg21648069
chr12:1157718
ERC1.GENEBODY
F


cg00192882
chr17:19291120
MFAP4.TSS1500
R


cg02838877
chr13:97873877
MBNL2.TSS1500
R


cg03841136
chr21:43136835
NCRNA00112.GENEBODY
R


cg09591406
chr17:3833873
ATP2A3.GENEBODY
R


cg09901529
chr10:75437967
AGAP5.GENEBODY
F
chr10:75434361-75434584
S_Shelf


cg25595636
chr11:61278148
LRRC10B.EXON1
F
chr11:61275825-61277329
S_Shore


cg02716826
chr9:33447032
SUGT1P1.GENEBODY
R
chr9:33447446-33447824
N_Shore


cg07017242
chr7:128047441
IMPDH1.GENEBODY
F
chr7:128045542-128046298
S_Shore


cg16944941
chr11:70391346
SHANK2.GENEBODY
F


cg18264519
chr2:97214296
ARID5A.GENEBODY
F
chr2:97215788-97216225
N_Shore


cg19626737
chr15:68633792
ITGA11.GENEBODY
F


cg21745110
chr11:19798742
NAV2.GENEBODY
R
chr11:19798537-19798949
Island


cg04098194
chr1:1241087
ACAP3.GENEBODY
R
chr1:1242400-1245185
N_Shore


cg07524505
chr11:44785843
TSPAN18.TSS200
R


cg11808936
chr4:7894203
AFAP1.UTR5
F


cg11503687
chr5:138205434
CTNNA1.GENEBODY
F


cg12116749
chr10:21245178
NEBL.GENEBODY
R


cg02047211
chr17:78932697
RPTOR.GENEBODY
R
chr17:78935043-78935307
N_Shelf


cg02839802
chr22:38963969
DMC1.GENEBODY
F
chr22:38965733-38966196
N_Shore


cg04278162
chr6:30182172
TRIM26.TSS1500
F
chr6:30180933-30182187
Island


cg19918429
chr3:122399781
PARP14.EXON1
F
chr3:122399655-122400190
Island


cg00156118
chr2:85473750
TCF7L1.GENEBODY
R


cg04545079
chr16:67599924
CTCF.UTR5
R
chr16:67595868-67597554
S_Shelf


cg08692676
chr6:134299594
TBPL1.UTR5
R


cg09342325
chr2:220371699
GMPPA.UTR3
F


cg11314042
chr6:143380966
AIG1.TSS1500
F
chr6:143381444-143381918
N_Shore


cg14326805
chr9:71737756
TJP2.UTR5
F
chr9:71736074-71737367
S_Shore


cg15018282
chr6:30181877
TRIM26.TSS1500
R
chr6:30180933-30182187
Island


cg25887619
chr7:101558435
CUX1.GENEBODY
R
chr7:101559402-101559625
N_Shore


cg03850117
chr16:87894334
SLC7A5.GENEBODY
R
chr16:87894359-87894566
N_Shore


cg15509065
chr19:36346314
KIRREL2.TSS1500
F
chr19:36347044-36348101
N_Shore


cg16105461
chr11:61485853
DAGLA.UTR5
F
chr11:61488132-61488357
N_Shelf


cg16933706
chr6:30181934
TRIM26.TSS1500
R
chr6:30180933-30182187
Island


cg19139618
chr17:46504791
SKAP1.GENEBODY
R
chr17:46507344-46507778
N_Shelf


cg21804531
chr14:90419290
C14orf143.GENEBODY
F
chr14:90420900-90421175
N_Shore


cg23735214
chr11:77595033
INTS4.GENEBODY
F


cg26329692
chr17:73126757
NT5C.GENEBODY
R
chr17:73127196-73127995
N_Shore


cg03478739
chr2:175712381
CHN1.GENEBODY
F


cg04828792
chr21:42733433
MX2.TSS1500
F


cg08258650
chr11:35441900
SLC1A2.TSS1500
F
chr11:35440375-35441882
S_Shore


cg08348709
chr17:37764802
NEUROD2.TSS1500
F
chr17:37761691-37763551
S_Shore


cg18085176
chr4:7939940
AFAP1.UTR5
F
chr4:7940563-7941853
N_Shore


cg00785029
chr21:43491755
UMODL1.GENEBODY
R


cg06804344
chr3:128778699
GP9.TSS1500
F


cg06865992
chr17:37764503
NEUROD2.TSS1500
R
chr17:37761691-37763551
S_Shore


cg08427782
chr6:166880989
RPS6KA2.GENEBODY
F


cg14059959
chr13:111144447
COL4A2.GENEBODY
R


cg18498622
chrX:151810246
GABRQ.GENEBODY
F
chrX:151806233-151806947
S_Shelf


cg20192387
chr6:166856056
RPS6KA2.GENEBODY
R


cg21917090
chr4:77816250
ANKRD56.UTR3
R
chr4:77818015-77819600
N_Shore


cg22359606
chr2:182545492
NEUROD1.TSS200
F
chr2:182547873-182549177
N_Shelf


cg24554839
chr1:166124903
MIR921.TSS1500
F


cg25788549
chr7:150786044
AGAP3.GENEBODY
F
chr7:150783480-150785040
S_Shore


cg08671326
chr3:194967958
C3orf21.GENEBODY
F


cg13920460
chr9:71735701
TJP2.TSS1500
R
chr9:71736074-71737367
N_Shore


cg19482025
chr11:128562245
FLI1.TSS200
F
chr11:128562671-128565011
N_Shore


cg04907173
chr11:65060386
POLA2.GENEBODY
F


cg05124770
chr22:24578799
SUSD2.GENEBODY
F
chr22:24581632-24582127
N_Shelf


cg22666115
chr6:30182186
TRIM26.TSS1500
F
chr6:30180933-30182187
Island


cg23641264
chr8:143748641
JRK.UTR5
F
chr8:143750759-143751448
N_Shelf


cg03979241
chr8:21916824
EPB49.EXON1
F
chr8:21914275-21914525
S_Shelf


cg07651914
chr7:100881986
CLDN15.TSS1500
F


cg13974838
chr9:98221619
PTCH1.GENEBODY
F


cg15612436
chr22:43897902
MPPED1.GENEBODY
R


cg16222790
chr8:144521374
ZC3H3.GENEBODY
R
chr8:144521358-144521608
Island


cg17066349
chr12:120130646
CIT.GENEBODY
F
chr12:120127973-120128291
S_Shelf


cg25320780
chr1:110933345
SLC16A4.UTR5
F


cg01877565
chr7:129414746
MIR183.GENEBODY
F
chr7:129418286-129422509
N_Shelf


cg04305228
chr22:18272333
MICAL3.UTR3
R
chr22:18275679-18275922
N_Shelf


cg06433132
chr19:39662346
PAK4.GENEBODY
R
chr19:39663600-39663815
N_Shore


cg10832281
chr11:35499741
PAMR1.GENEBODY
F


cg14627862
chr6:169641232
THBS2.GENEBODY
F
chr6:169641803-169642020
N_Shore


cg19695266
chr1:1241672
ACAP3.GENEBODY
R
chr1:1242400-1245185
N_Shore


cg02619205
chr9:117157157
AKNA.TSS1500
F
chr9:117160139-117161064
N_Shelf


cg03539717
chr19:13065086
GADD45GIP1.GENEBODY
R
chr19:13067585-13068152
N_Shelf


cg04007028
chr17:36735584
SRCIN1.GENEBODY
R
chr17:36734659-36735246
S_Shore


cg05499054
chr8:75148806
JPH1.UTR3
R


cg11401784
chr1:16092264
FBLIM1.GENEBODY
R


cg20491406
chr1:201693818
NAV1.GENEBODY
R


cg23377852
chr5:1339812
CLPTM1L.GENEBODY
F
chr5:1339662-1340082
Island


cg00912746
chr1:33350709
HPCA.TSS1500
F
chr1:33351686-33352397
N_Shore


cg01557332
chr6:169641045
THBS2.GENEBODY
R
chr6:169641803-169642020
N_Shore


cg08160706
chr16:11876111
ZC3H7A.GENEBODY
F


cg10716524
chr11:474509
PTDSS2.GENEBODY
R
chr11:472781-473065
S_Shore


cg11410436
chr16:52581609
TOX3.UTR5
F
chr16:52581293-52581610
Island


cg19432362
chr13:46426263
SIAH3.TSS1500
F


cg03107310
chr10:86094757
FAM190B.UTR5
F


cg06097994
chr17:77043171
C1QTNF1.GENEBODY
F
chr17:77043741-77044489
N_Shore


cg13290371
chr7:5518071
FBXL18.UTR3
R
chr7:5521368-5521615
N_Shelf


cg13948413
chr1:236687580
LGALS8.UTR5
F
chr1:236687071-236687608
Island


cg15027294
chr12:1609537
LOC100292680.TSS200
R


cg15962197
chr1:41704561
SCMH1.UTR5
R
chr1:41706957-41708327
N_Shelf


cg17097293
chr19:3655825
PIP5K1C.GENEBODY
F
chr19:3659641-3659949
N_Shelf


cg21464975
chr17:60828260
MARCH10.GENEBODY
R


cg21832801
chr11:107579390
SLN.UTR5
R


cg22019158
chr1:27926683
AHDC1.UTR5
R
chr1:27929705-27930866
N_Shelf


cg05212460
chr7:2149814
MAD1L1.GENEBODY
R


cg11856932
chr12:53447059
TENC1.UTR5
F
chr12:53448008-53448406
N_Shore


cg13160058
chr8:26243215
BNIP3L.GENEBODY
F
chr8:26240290-26241017
S_Shelf


cg15118447
chr6:159220343
EZR.GENEBODY
F


cg22962041
chr17:49235043
NME1-NME2.GENEBODY
R
chr17:49230686-49231247
S_Shelf


cg25619638
chr2:220310232
SPEG.GENEBODY
F
chr2:220309637-220309893
S_Shore


cg11076275
chr1:207069654
IL24.TSS1500
F


cg13808641
chr9:96006533
WNK2.GENEBODY
R
chr9:96009844-96010101
N_Shelf


cg20666533
chr13:67714028
PCDH9.GENEBODY
F


cg22311015
chr2:241630042
AQP12A.TSS1500
F


cg05712010
chr1:230895283
CAPN9.GENEBODY
R


cg06488150
chr7:6476003
DAGLB.GENEBODY
F


cg08969344
chr6:34031597
GRM4.GENEBODY
R


cg09537448
chr7:129414567
MIR96.GENEBODY
F
chr7:129418286-129422509
N_Shelf


cg18171392
chr22:24938255
C22orf13.UTR3
F


cg20951539
chr6:36367819
PXT1.GENEBODY
R


cg21635706
chr15:69432565
MIR548H4.GENEBODY
R


cg23375717
chr11:20883318
NELL1.GENEBODY
F


cg25670451
chr12:6487677
SCNN1A.TSS1500
R


cg09901733
chr17:1731852
RPA1.TSS1500
R
chr17:1732834-1733612
N_Shore


cg16640855
chr2:182543233
NEUROD1.GENEBODY
R


cg22047469
chr1:1110107
TTLL10.UTR5
R
chr1:1109314-1110145
Island


cg22468751
chr6:136824489
MAP7.GENEBODY
F


cg12299554
chr15:94840953
MCTP2.TSS1500
R


cg22169990
chr7:150786051
AGAP3.GENEBODY
F
chr7:150783480-150785040
S_Shore


cg23286081
chr10:125775778
CHST15.GENEBODY
R


cg00005437
chr17:18010740
DRG2.UTR3
F


cg01132785
chr4:528175
PIGG.GENEBODY
F
chr4:529166-529556
N_Shore


cg02124184
chr5:72950691
RGNEF.UTR5
F


cg05940240
chr22:41762302
TEF.TSS1500
F


cg07096883
chr7:149979234
ACTR3C.GENEBODY
R


cg10206969
chr7:5518392
FBXL18.UTR3
F
chr7:5521368-5521615
N_Shelf


cg12941836
chr3:52869288
MUSTN1.TSS200
F


cg19254163
chr11:60623782
GPR44.TSS1500
R
chr11:60619924-60621111
S_Shelf


cg27412310
chr11:75146692
GDPD5.GENEBODY
R


cg07414392
chr9:71735648
TJP2.TSS1500
R
chr9:71736074-71737367
N_Shore


cg13568213
chr9:136387235
TMEM8C.GENEBODY
F


cg02482603
chr1:174843754
RABGAP1L.TSS1500
F


cg05380808
chr1:210820877
HHAT.GENEBODY
R


cg05593510
chr5:176249224
UNC5A.GENEBODY
R
chr5:176244559-176245284
S_Shelf


cg07505680
chr8:1933651
KBTBD11.UTR5
F


cg08539179
chr1:227915948
LOC100130093.TSS1500
R
chr1:227916425-227916736
N_Shore


cg10068572
chr10:35687029
CCNY.GENEBODY
F


cg11065015
chr20:327170
NRSN2.TSS200
R
chr20:327376-328977
N_Shore


cg24092939
chr12:49181056
ADCY6.UTR5
F
chr12:49182421-49182658
N_Shore


cg24321971
chr11:27406919
LGR4.GENEBODY
R


cg21887193
chr7:150786082
AGAP3.GENEBODY
F
chr7:150783480-150785040
S_Shore


cg02108198
chr7:99527876
GJC3.TSS1500
F


cg14755690
chr7:128868265
AHCYL2.GENEBODY
R
chr7:128864320-128865655
S_Shelf


cg17476271
chr11:128562408
FLI1.TSS1500
F
chr11:128562671-128565011
N_Shore


cg24522085
chr2:169556419
LASS6.GENEBODY
F


cg04785838
chr6:30181742
TRIM26.TSS1500
F
chr6:30180933-30182187
Island


cg08529481
chr1:36832173
STK40.UTR5
F


cg17838427
chr1:204653956
LRRN2.UTR5
F
chr1:204654132-204654885
N_Shore


cg06011067
chr6:110677913
C6orf186.GENEBODY
R
chr6:110678854-110679108
N_Shore


cg07562888
chr10:80883720
ZMIZ1.UTR5
F


cg10598711
chr5:72470395
TMEM174.UTR3
R


cg12417176
chr15:55788778
DYX1C1.GENEBODY
F
chr15:55790301-55790754
N_Shore


cg21738316
chrX:153688775
PLXNA3.GENEBODY
F
chrX:153688592-153688860
Island


cg22626525
chr1:20008900
TMCO4.UTR3
F
chr1:20005510-20005865
S_Shelf


cg23956760
chr19:19178708
SLC25A42.UTR5
R
chr19:19174262-19174995
S_Shelf


cg24352878
chr1:8772712
RERE.UTR5
R


cg27654966
chr7:101558400
CUX1.GENEBODY
R
chr7:101559402-101559625
N_Shore


cg13714797
chr9:7103479
KDM4C.GENEBODY
R


cg23971638
chr12:741507
NINJ2.GENEBODY
R


cg24204017
chr3:57999988
FLNB.GENEBODY
F


cg26017492
chr6:166891729
RPS6KA2.GENEBODY
F


cg00369376
chr2:182542510
NEUROD1.UTR3
F


cg02864954
chr6:154535553
IPCEF1.GENEBODY
R


cg03505501
chr11:115371789
CADM1.GENEBODY
R
chr11:115373574-115375881
N_Shore


cg05161682
chr13:111107167
COL4A2.GENEBODY
R
chr13:111109139-111109652
N_Shore


cg09427605
chr4:146740968
ZNF827.GENEBODY
R


cg13396830
chr6:30181581
TRIM26.TSS1500
R
chr6:30180933-30182187
Island


cg16427420
chr17:74526161
CYGB.GENEBODY
F


cg26504422
chr19:44277951
KCNN4.GENEBODY
R
chr19:44278273-44278777
N_Shore


cg10156302
chr15:64202084
DAPK2.GENEBODY
F


cg13866253
chr11:77093001
PAK1.GENEBODY
R


cg14465207
chr2:10951250
PDIA6.GENEBODY
F
chr2:10952402-10953384
N_Shore


cg14695840
chr9:71737258
TJP2.UTR5
R
chr9:71736074-71737367
Island


cg20592124
chr2:65290738
CEP68.UTR5
R


cg01248385
chr13:113636953
MCF2L.GENEBODY
R
chr13:113635654-113635899
S_Shore


cg08641990
chr1:54822503
SSBP3.GENEBODY
F
chr1:54821990-54822333
S_Shore


cg14864994
chr12:6496214
LTBR.GENEBODY
F
chr12:6492889-6493522
S_Shelf


cg20679581
chr8:10222777
MSRA.GENEBODY
F


cg24904739
chr17:77959804
TBC1D16.GENEBODY
R


cg25193885
chr11:70328867
SHANK2.GENEBODY
F
chr11:70332266-70333413
N_Shelf


cg03127370
chr16:2520192
NTN3.TSS1500
R
chr16:2521086-2525929
N_Shore


cg21972567
chr5:158350708
EBF1.GENEBODY
F


cg25076197
chr7:104681440
MLL5.GENEBODY
F


cg15723222
chr17:59222476
BCAS3.GENEBODY
R


cg19420604
chr17:60828406
MARCH10.GENEBODY
F


cg03467001
chr1:183857649
RGL1.GENEBODY
R


cg04220881
chr7:152524814
ACTR3B.GENEBODY
F


cg13520715
chr21:43135854
C21orf129.GENEBODY
R


cg19272238
chr17:76220898
BIRC5.UTR3
F


cg20628733
chr1:3524459
MEGF6.GENEBODY
R
chr1:3527619-3528078
N_Shelf


cg26985681
chr16:15135397
NTAN1.GENEBODY
F


cg09853822
chr17:4712456
PLD2.GENEBODY
F
chr17:4710014-4710960
S_Shore


cg15460454
chr7:1974654
MAD1L1.GENEBODY
R
chr7:1976258-1976464
N_Shore


cg22532234
chr19:40229215
CLC.TSS1500
R


cg04746649
chr2:169401301
LASS6.GENEBODY
R


cg09540626
chr16:2590751
PDPK1.GENEBODY
F
chr16:2588034-2588556
S_Shelf


cg22244768
chr17:55634551
MSI2.GENEBODY
F


cg26504421
chr17:71339361
SDK2.GENEBODY
R


cg03091070
chr6:169641288
THBS2.GENEBODY
R
chr6:169641803-169642020
N_Shore


cg19974120
chr21:42839625
TMPRSS2.GENEBODY
F


cg26344024
chr3:71357195
FOXP1.UTR5
R


cg27126442
chr4:106473806
FLJ20184.UTR5
F


cg01132579
chr17:55588940
MSI2.GENEBODY
R


cg03029090
chr15:58812960
LIPC.GENEBODY
R


cg06694239
chr7:128807764
TSPAN33.UTR3
F
chr7:128809089-128809393
N_Shore


cg08702745
chr13:111138063
COL4A2.GENEBODY
R


cg13793782
chr9:135995093
RALGDS.GENEBODY
F
chr9:135995969-135996954
N_Shore


cg12248883
chr11:6219573
OR52W1.TSS1500
F


cg00300637
chr5:319433
AHRR.GENEBODY
R
chr5:320788-323010
N_Shore


cg01661001
chr20:44439932
UBE2C.TSS1500
F
chr20:44440946-44441655
N_Shore


cg04260891
chr7:75514575
RHBDD2.GENEBODY
F


cg12686273
chr16:3085867
CCDC64B.TSS1500
F
chr16:3086283-3086968
N_Shore


cg13363823
chr1:40362907
MYCL1.UTR3
F
chr1:40366595-40368213
N_Shelf


cg24688343
chr17:61229244
TANC2.GENEBODY
F


cg13844853
chr1:94062769
BCAR3.GENEBODY
F


cg20505457
chr14:69388953
ACTN1.GENEBODY
F


cg02923393
chr16:1543003
TELO2.TSS1500
R
chr16:1543098-1544426
N_Shore


cg10708739
chr17:57465550
YPEL2.GENEBODY
F


cg24791666
chr3:39192215
CSRNP1.UTR5
F
chr3:39194241-39195359
N_Shelf


cg00078299
chr8:124284379
ZHX1.UTR5
R
chr8:124286209-124287666
N_Shore


cg00474798
chr2:84684489
SUCLG1.GENEBODY
R
chr2:84686005-84686751
N_Shore


cg01267165
chr16:11681599
LITAF.TSS1500
F
chr16:11680008-11681275
S_Shore


cg02405813
chr6:83072522
TPBG.TSS1500
F
chr6:83073416-83075319
N_Shore


cg08869273
chr11:413594
SIGIRR.UTR5
R
chr11:416419-417650
N_Shelf


cg09238199
chr13:111097777
COL4A2.GENEBODY
F


cg09333109
chr19:51532580
KLK11.TSS1500
F
chr19:51535218-51535475
N_Shelf


cg10813585
chr1:114305956
RSBN1.UTR3
R
chr1:114301514-114302272
S_Shelf


cg01262667
chr19:19385393
TM6SF2.TSS1500
F
chr19:19383703-19384283
S_Shore


cg03581459
chr14:105780137
PACS2.TSS1500
F
chr14:105780339-105782027
N_Shore


cg04961866
chr16:3085686
CCDC64B.TSS200
R
chr16:3086283-3086968
N_Shore


cg05263838
chr2:227659406
IRS1.UTR3
F
chr2:227662082-227664912
N_Shelf


cg11908131
chr2:106685045
C2orf40.GENEBODY
R
chr2:106681982-106682403
S_Shelf


cg14377791
chr19:40169912
LOC400696.TSS200
F


cg16081441
chr17:74463560
AANAT.TSS200
R


cg20169296
chr10:103367727
RP11-529I10.4.GENEBODY
R


cg06915226
chr2:70960959
ADD2.UTR5
F


cg07121199
chr1:205537752
MFSD4.TSS1500
R
chr1:205537751-205538443
Island


cg16929041
chr17:26648951
TMEM97.GENEBODY
F
chr17:26645290-26645614
S_Shelf


cg01796143
chr1:236687575
LGALS8.UTR5
R
chr1:236687071-236687608
Island


cg01897496
chr2:182545209
NEUROD1.EXON1
R
chr2:182547873-182549177
N_Shelf


cg02445907
chr6:36294404
C6orf222.GENEBODY
F


cg10351284
chr8:125617225
MTSS1.GENEBODY
F


cg12778007
chr14:72041267
SIPA1L1.UTR5
F


cg18319790
chr14:100788777
C14orf68.TSS1500
R


cg21719937
chr12:5564478
NTF3.GENEBODY
R


cg21740204
chr9:72873544
SMC5.TSS1500
F
chr9:72873689-72874264
N_Shore


cg24657047
chr15:77317370
PSTPIP1.GENEBODY
R
chr15:77320150-77320456
N_Shelf


cg26037504
chr12:56113808
RDH5.TSS1500
F
chr12:56109798-56110298
S_Shelf


cg26782539
chr10:134061662
STK32C.GENEBODY
F


cg02010776
chr16:18938091
SMG1.TSS1500
R
chr16:18937030-18938126
Island


cg03920522
chr7:94047477
COL1A2.GENEBODY
R


cg08946575
chr1:85931072
DDAH1.TSS200
F
chr1:85929940-85931168
Island


cg10039567
chr1:112395111
KCND3.GENEBODY
R


cg10316635
chr1:62208645
INADL.UTR5
R
chr1:62207827-62208818
Island


cg13973639
chr6:42858710
C6orf226.TSS200
R
chr6:42858169-42858960
Island


cg15653828
chr6:34513187
SPDEF.UTR5
F
chr6:34512063-34512266
S_Shore


cg19153095
chr8:106811143
ZFPM2.GENEBODY
F


cg02531277
chr7:101558597
CUX1.GENEBODY
R
chr7:101559402-101559625
N_Shore


cg03036777
chr1:33648819
TRIM62.TSS1500
F
chr1:33646613-33647878
S_Shore


cg03621100
chr12:104322919
LOC253724.GENEBODY
F
chr12:104323017-104324811
N_Shore


cg08706567
chr1:43814983
MPL.GENEBODY
F
chr1:43814305-43815277
Island


cg08905114
chr9:95897015
NINJ1.TSS1500
R
chr9:95896007-95897016
Island


cg09702010
chr19:51531393
KLK11.TSS1500
F
chr19:51535218-51535475
N_Shelf


cg13264672
chr7:39993440
CDK13.GENEBODY
F
chr7:39988922-39991612
S_Shore


cg14607161
chr6:32084298
ATF6B.GENEBODY
R


cg17141902
chr9:95897216
NINJ1.TSS1500
F
chr9:95896007-95897016
S_Shore


cg26681687
chr4:77874155
SEPT11.GENEBODY
F
chr4:77869440-77872122
S_Shelf


cg05155047
chr5:168719
PLEKHG4B.GENEBODY
F
chr5:169578-169798
N_Shore


cg10754794
chr10:93916288
CPEB3.GENEBODY
F


cg15744692
chr15:45671195
LOC145663.GENEBODY
F
chr15:45669970-45671029
S_Shore


cg00955867
chr1:160337038
NHLH1.EXON1
R
chr1:160340604-160340843
N_Shelf


cg01470599
chr9:38422794
IGFBPL1.GENEBODY
F
chr9:38423947-38424584
N_Shore


cg06508379
chr19:19104064
SFRS14.UTR3
R


cg07491702
chr15:43030817
CDAN1.TSS1500
R
chr15:43028413-43029346
S_Shore


cg08673532
chr16:87422913
FBXO31.GENEBODY
F
chr16:87425137-87426677
N_Shelf


cg16320329
chr3:45981161
FYCO1.GENEBODY
F


cg16321266
chr7:129414894
MIR183.TSS200
F
chr7:129418286-129422509
N_Shelf


cg17033622
chr11:128568943
FLI1.GENEBODY
R
chr11:128562671-128565011
S_Shelf


cg18911861
chr6:42858743
C6orf226.TSS200
R
chr6:42858169-42858960
Island


cg22791543
chr5:127416532
FLJ33630.GENEBODY
R
chr5:127418594-127420512
N_Shelf


cg27360567
chr3:49941613
MST1R.TSS1500
F
chr3:49940099-49940431
S_Shore


cg00764796
chr16:433504
LOC100134368.GENEBODY
R
chr16:431189-432810
S_Shore


cg08843859
chr1:184566345
C1orf21.GENEBODY
F


cg09027133
chr1:25945042
MAN1C1.GENEBODY
F
chr1:25942661-25943191
S_Shore


cg12145018
chr14:103912507
MARK3.GENEBODY
F


cg14087413
chr9:35848330
TMEM8B.GENEBODY
R
chr9:35846310-35846638
S_Shore


cg18449361
chr6:2689154
MYLK4.GENEBODY
R
chr6:2685400-2685625
S_Shelf


cg22393461
chr1:10010658
NMNAT1.UTR5
F


cg22572454
chr17:74463767
AANAT.GENEBODY
F


cg00034154
chr19:10337163
S1PR2.UTR5
F
chr19:10334618-10335511
S_Shore


cg04656424
chr16:88839844
FAM38A.GENEBODY
F
chr16:88838112-88838459
S_Shore


cg06561646
chr17:35873369
DUSP14.UTR3
F
chr17:35872722-35873026
S_Shore


cg07119973
chr17:43109221
DCAKD.GENEBODY
R
chr17:43111525-43111732
N_Shelf


cg08637583
chr15:44828465
EIF3J.TSS1500
R
chr15:44828637-44829949
N_Shore


cg14453201
chr5:320888
AHRR.GENEBODY
R
chr5:320788-323010
Island


cg15507486
chr19:46627896
IGFL3.EXON1
F


cg21093368
chr17:8055834
PER1.TSS200
F
chr17:8054550-8055835
Island


cg26477169
chr17:75196864
SEC14L1.GENEBODY
R


cg26692003
chr3:13063165
IQSEC1.GENEBODY
R


cg27262398
chr11:107578793
SLN.UTR5
R


cg27559097
chr2:144987743
GTDC1.UTR5
F


cg18407095
chr2:26846581
CIB4.GENEBODY
R


cg00225157
chr6:33173038
HSD17B8.GENEBODY
F
chr6:33172289-33172823
S_Shore


cg00648184
chr17:60828157
MARCH10.GENEBODY
R


cg03035849
chr6:91003200
BACH2.UTR5
R
chr6:91004795-91006944
N_Shore


cg05294243
chr19:51569106
KLK13.TSS1500
F
chr19:51568154-51568412
S_Shore


cg05581469
chr12:49413435
MLL2.UTR3
F
chr12:49412299-49412756
S_Shore


cg13296983
chr12:6436553
PLEKHG6.GENEBODY
F
chr12:6438272-6438931
N_Shore


cg01448470
chr1:18518226
IGSF21.GENEBODY
R


cg06747907
chr1:16091100
FBLIM1.UTR5
R


cg04138378
chr7:95849192
MIR591.TSS200
R


cg15152301
chr3:50425602
CACNA2D2.GENEBODY
F


cg25882455
chr22:38599073
MAFF.EXON1
F
chr22:38597785-38598988
S_Shore


cg02862897
chr17:79793088
DYSFIP1.TSS200
F
chr17:79790530-79791553
S_Shore


cg05036991
chr2:155089854
GALNT13.GENEBODY
F


cg13508369
chr9:129884026
ANGPTL2.UTR5
R


cg15076368
chr3:39224943
XIRP1.UTR3
R
chr3:39222280-39222670
S_Shelf


cg15204874
chr1:54822298
SSBP3.GENEBODY
R
chr1:54821990-54822333
Island


cg18211633
chr12:122205609
TMEM120B.GENEBODY
R


cg19287817
chr19:15391339
BRD4.TSS200
F


cg00985958
chr6:71605996
B3GAT2.GENEBODY
F


cg04617549
chr19:51569622
KLK13.TSS1500
F
chr19:51568154-51568412
S_Shore


cg04918002
chr16:87423124
FBXO31.GENEBODY
R
chr16:87425137-87426677
N_Shelf


cg05487134
chr17:40489569
STAT3.GENEBODY
F


cg05928980
chr1:29567425
PTPRU.GENEBODY
R
chr1:29562745-29565307
S_Shelf


cg07824564
chr1:179050911
TOR3A.TSS200
F
chr1:179051075-179051948
N_Shore


cg13261623
chr17:74462685
AANAT.GENEBODY
R


cg13698883
chr9:38422614
IGFBPL1.GENEBODY
F
chr9:38423947-38424584
N_Shore


cg26279814
chr17:37617607
CDK12.TSS200
F
chr17:37617531-37618045
Island


cg00193613
chr17:77042810
C1QTNF1.GENEBODY
R
chr17:77043741-77044489
N_Shore


cg06201861
chr16:84877964
CRISPLD2.GENEBODY
F


cg23551605
chr2:236442942
AGAP1.GENEBODY
F
chr2:236443815-236444025
N_Shore


cg25482454
chr2:85988369
ATOH8.GENEBODY
R


cg06091094
chr11:44927766
TSPAN18.UTR5
F


cg10426951
chr1:54821910
SSBP3.GENEBODY
F
chr1:54821990-54822333
N_Shore


cg17490445
chr7:32623673
AVL9.UTR3
F


cg17699214
chr4:40890013
APBB2.GENEBODY
R


cg00564723
chr10:75632066
CAMK2G.GENEBODY
F
chr10:75633600-75634796
N_Shore


cg04999036
chr15:42566375
TMEM87A.TSS1500
R
chr15:42566198-42566404
Island


cg06130787
chr19:51523550
KLK10.TSS1500
F
chr19:51522004-51522803
S_Shore


cg09923953
chr19:51525638
KLK11.UTR3
F
chr19:51522004-51522803
S_Shelf


cg14414406
chr9:100326029
TMOD1.GENEBODY
F


cg19392379
chr10:123909426
TACC2.GENEBODY
R


cg10585321
chr9:135995491
RALGDS.GENEBODY
R
chr9:135995969-135996954
N_Shore


cg12581298
chr7:1080836
C7orf50.GENEBODY
R
chr7:1080835-1081069
Island


cg13548543
chr9:34460044
DNAI1.GENEBODY
F
chr9:34457375-34458892
S_Shore


cg18322589
chr10:123909456
TACC2.GENEBODY
F


cg25285041
chr1:41627631
SCMH1.UTR5
R


cg00664743
chr22:31300253
OSBP2.GENEBODY
R
chr22:31301702-31302133
N_Shore


cg03717830
chr6:30182244
TRIM26.TSS1500
R
chr6:30180933-30182187
S_Shore


cg18263988
chr3:111582491
PHLDB2.UTR5
R
chr3:111578237-111578739
S_Shelf


cg02312706
chr16:87384599
FBXO31.GENEBODY
F


cg03762081
chr19:51523565
KLK10.TSS1500
F
chr19:51522004-51522803
S_Shore


cg17585356
chr17:78857121
RPTOR.GENEBODY
R
chr17:78857630-78857866
N_Shore


cg19727124
chr1:6553227
PLEKHG5.GENEBODY
R
chr1:6550083-6551115
S_Shelf


cg23045716
chr4:1201881
LOC100130872.GENEBODY
R
chr4:1202956-1203200
N_Shore


cg26530485
chr1:23496304
LUZP1.TSS1500
F


cg27119919
chr11:60684332
TMEM109.UTR5
F
chr11:60681552-60682268
S_Shelf


cg11634198
chr17:37764158
NEUROD2.UTR5
F
chr17:37764092-37764304
Island


cg15798221
chr17:62773704
LOC146880.GENEBODY
R
chr17:62774366-62777797
N_Shore


cg24112733
chr7:38255578
STARD3NL.GENEBODY
F


cg08897952
chr11:126229062
ST3GAL4.UTR5
R
chr11:126225355-126226073
S_Shelf


cg13969327
chr7:127526253
SND1.GENEBODY
F


cg18253971
chr18:21900171
OSBPL1A.GENEBODY
F


cg20104456
chr19:51568523
KLK13.TSS200
R
chr19:51568154-51568412
S_Shore


cg24247667
chr17:74463439
AANAT.TSS200
F


cg24901995
chr11:888570
CHID1.GENEBODY
R
chr11:888684-888981
N_Shore


cg14225450
chr6:169637832
THBS2.GENEBODY
F
chr6:169641803-169642020
N_Shelf


cg01119831
chr7:2119608
MAD1L1.GENEBODY
R
chr7:2116367-2116781
S_Shelf


cg01593787
chr13:111182949
RAB20.GENEBODY
F


cg16451995
chr16:8942340
PMM2.UTR3
R


cg17523945
chr19:46732351
IGFL1.TSS1500
F


cg21323630
chr3:51995784
PCBP4.UTR5
R


cg23712594
chr1:226591890
PARP1.GENEBODY
R
chr1:226595333-226595939
N_Shelf


cg17170262
chr1:184715203
EDEM3.GENEBODY
F


cg05338397
chr1:15466556
C1orf126.GENEBODY
R


cg23682934
chr17:42885322
GJC1.UTR5
R


cg06195280
chr17:6658706
XAF1.TSS1500
F


cg01766396
chr2:198436483
RFTN2.UTR3
F


cg07990556
chr4:159792176
FNIP2.GENEBODY
F


cg24899626
chr8:10512724
RP1L1.TSS200
F


cg19028997
chr1:205603040
ELK4.TSS1500
R
chr1:205600493-205601432
S_Shore


cg12562403
chr12:3214145
TSPAN9.UTR5
R


cg08228249
chr22:22062300
YPEL1.GENEBODY
F
chr22:22058079-22058304
S_Shelf


cg27634115
chr2:42423477
EML4.GENEBODY
F


cg03861347
chr20:46412713
SULF2.UTR5
F
chr20:46413742-46415507
N_Shore


cg07941953
chr20:10508668
C20orf94.GENEBODY
R


cg03187411
chr7:110482491
IMMP2L.GENEBODY
R


cg03223734
chr20:20180211
C20orf26.GENEBODY
R


cg23793194
chr17:37763735
NEUROD2.UTR5
R
chr17:37764092-37764304
N_Shore


cg07831164
chr16:10836225
NUBP1.TSS1500
R
chr16:10837584-10838196
N_Shore


cg20674206
chr1:63004738
DOCK7.GENEBODY
F


cg22721827
chr16:2520958
NTN3.TSS1500
F
chr16:2521086-2525929
N_Shore


cg27096416
chr7:140599947
BRAF.GENEBODY
F


cg03419151
chr17:6658728
XAF1.TSS1500
F


cg05420057
chr17:36721297
SRCIN1.GENEBODY
F
chr17:36719544-36719938
S_Shore


cg05950943
chr16:2520971
NTN3.TSS1500
F
chr16:2521086-2525929
N_Shore


cg03243893
chr8:2005683
MYOM2.GENEBODY
R
chr8:2003809-2004059
S_Shore


cg20255723
chr22:45073031
PRR5.UTR5
R


cg25275372
chr17:964596
ABR.GENEBODY
F


cg00284708
chr8:43147581
POTEA.TSS200
F


cg09305096
chr2:189191655
GULP1.UTR5
R


cg16696035
chr17:17126176
FLCN.GENEBODY
R
chr17:17124698-17124931
S_Shore


cg02966899
chr15:64793532
ZNF609.GENEBODY
R


cg09606564
chr17:19290353
MFAP4.GENEBODY
F


cg00332588
chr8:43147564
POTEA.TSS200
R


cg08041350
chr17:25819112
KSR1.UTR5
R


cg14074652
chr9:136662289
VAV2.GENEBODY
F
chr9:136659111-136659329
S_Shelf


cg19963589
chr1:54822103
SSBP3.GENEBODY
F
chr1:54821990-54822333
Island


cg09309024
chr16:29837267
MVP.UTR5
F


cg11952344
chr17:80398854
HEXDC.GENEBODY
F
chr17:80397431-80397642
S_Shore


cg20431135
chr17:19290762
MFAP4.TSS1500
F


cg19155699
chr3:196050902
TM4SF19.GENEBODY
F


cg23704362
chr8:67405742
C8orf46.EXON1
F


cg19991383
chr3:55034387
CACNA2D3.GENEBODY
F


cg00172603
chr1:54822031
SSBP3.GENEBODY
F
chr1:54821990-54822333
Island


cg06431681
chr2:202330990
STRADB.GENEBODY
F


cg14461974
chr2:3318039
TSSC1.GENEBODY
R
chr2:3317676-3317935
S_Shore


cg15119221
chr17:19290755
MFAP4.TSS1500
F


cg21831649
chr1:16050377
PLEKHM2.GENEBODY
R
chr1:16053616-16053975
N_Shelf


cg06087554
chr16:31151917
PRSS36.GENEBODY
R
chr16:31153556-31154474
N_Shore


cg01293647
chr17:37764264
NEUROD2.TSS200
R
chr17:37764092-37764304
Island


cg14281144
chr9:38421899
IGFBPL1.GENEBODY
F
chr9:38423947-38424584
N_Shelf


cg13726218
chr13:72438249
DACH1.GENEBODY
R
chr13:72439362-72440059
N_Shore


cg17892159
chr2:42274610
PKDCC.TSS1500
F


cg10414350
chr8:10210282
MSRA.GENEBODY
R


cg20326410
chr1:53600821
SLC1A7.GENEBODY
R


cg06785060
chr1:42180981
HIVEP3.UTR5
F


cg07685557
chr16:85685994
KIAA0182.GENEBODY
F
chr16:85684107-85684491
S_Shore


cg08520443
chr17:746641
NXN.GENEBODY
R
chr17:744617-744907
S_Shore


cg17322655
chr2:242802127
PDCD1.TSS1500
F
chr2:242805752-242806034
N_Shelf


cg00545232
chr13:93923232
GPC6.GENEBODY
R


cg11019127
chr11:115369647
CADM1.GENEBODY
F
chr11:115373574-115375881
N_Shelf


cg08151442
chr2:238632428
LRRFIP1.GENEBODY
F


cg16719771
chr8:43147554
POTEA.TSS200
R


cg20944379
chr1:207069392
IL24.TSS1500
R


cg03679521
chr17:37764153
NEUROD2.UTR5
F
chr17:37764092-37764304
Island


cg09440603
chr21:43105616
NCRNA00111.GENEBODY
F
chr21:43109349-43109687
N_Shelf


cg07360805
chr20:36148457
BLCAP.UTR5
F
chr20:36148603-36150136
N_Shore


cg01796800
chr17:55595732
MSI2.GENEBODY
F


cg06429887
chr14:24600500
FITM1.TSS200
F
chr14:24601498-24601700
N_Shore


cg10603757
chr22:37621745
RAC2.UTR3
R


cg13440795
chr8:10210267
MSRA.GENEBODY
R


cg03889044
chr2:242802099
PDCD1.TSS1500
F
chr2:242805752-242806034
N_Shelf


cg08200851
chr6:5472095
FARS2.GENEBODY
F


cg09414280
chr12:120130253
CIT.GENEBODY
R
chr12:120127973-120128291
S_Shore


cg21641186
chr3:126200897
UROC1.UTR3
R


cg21830368
chr17:75373327
SEPT9.UTR5
R
chr17:75368688-75370506
S_Shelf


cg04951371
chr2:3317860
TSSC1.GENEBODY
F
chr2:3317676-3317935
Island


cg21557724
chr2:3317928
TSSC1.GENEBODY
R
chr2:3317676-3317935
Island


cg12716832
chr22:45073165
PRR5.UTR5
R


cg04436083
chr4:24567220
DHX15.GENEBODY
R


cg11125249
chr3:148737622
GYG1.GENEBODY
F


cg11993925
chr19:44307056
LYPD5.TSS1500
F
chr19:44302665-44303176
S_Shelf


cg15293827
chr4:2827194
SH3BP2.GENEBODY
F


cg27531366
chr1:27627058
WDTC1.GENEBODY
F


cg01943029
chr16:31715088
C16orf67.GENEBODY
F
chr16:31711839-31712343
S_Shelf


cg13027937
chr7:152525220
ACTR3B.GENEBODY
F


cg16623710
chr22:45073049
PRR5.UTR5
F


cg00679520
chr12:63133578
PPM1H.GENEBODY
F


cg03742724
chr6:161838997
PARK2.GENEBODY
R


cg14300048
chr9:72046240
APBA1.UTR3
F


cg09720012
chr4:108637177
PAPSS1.GENEBODY
R
chr4:108640845-108641835
N_Shelf


cg22689630
chr19:51568918
KLK13.TSS1500
F
chr19:51568154-51568412
S_Shore


cg27068996
chr19:51513883
KLK9.TSS1500
F


cg09535960
chr8:23193704
LOXL2.GENEBODY
F


cg02734358
chr4:90227074
GPRIN3.UTR5
R
chr4:90228714-90229010
N_Shore


cg03118626
chr19:51523252
KLK10.UTR5
R
chr19:51522004-51522803
S_Shore


cg06358171
chr1:54822008
SSBP3.GENEBODY
R
chr1:54821990-54822333
Island


cg06440275
chr8:2005701
MYOM2.GENEBODY
R
chr8:2003809-2004059
S_Shore


cg09393675
chr17:37764250
NEUROD2.TSS200
R
chr17:37764092-37764304
Island


cg20164964
chr12:3213850
TSPAN9.UTR5
R


cg02175739
chr11:875980
CHID1.GENEBODY
R


cg08969377
chr17:80915263
B3GNTL1.GENEBODY
R
chr17:80918218-80919258
N_Shelf


cg00317626
chr1:53600741
SLC1A7.GENEBODY
F


cg09382492
chr17:74463681
AANAT.GENEBODY
F


cg02516456
chr11:1025091
MUC6.GENEBODY
R
chr11:1024746-1025359
Island


cg03737367
chr19:50005045
MIR150.TSS1500
R


cg13446863
chr9:139259726
CARD9.GENEBODY
R
chr9:139257842-139259075
S_Shore


cg02048220
chr14:91141833
TTC7B.GENEBODY
R


cg06760830
chr1:47079672
MOBKL2C.GENEBODY
F
chr1:47078580-47078967
S_Shore


cg11912239
chr17:76220608
BIRC5.UTR3
F


cg13525276
chr14:81426012
TSHR.GENEBODY
F


cg14025021
chr15:43809510
MAP1A.TSS1500
F


cg16960943
chr2:236417185
AGAP1.GENEBODY
R


cg17741629
chr13:50024703
SETDB2.TSS1500
R


cg04135110
chr5:346695
AHRR.GENEBODY
R
chr5:343449-344535
S_Shelf


cg18722086
chr3:113380072
KIAA2018.GENEBODY
R


cg23141629
chr13:45792582
GTF2F2.GENEBODY
R


cg23571857
chr17:6658898
XAF1.TSS1500
F


cg05416911
chr12:7176049
C1S.GENEBODY
F


cg15341350
chr12:119446891
SRRM4.GENEBODY
F


cg15382095
chr17:37762367
NEUROD2.GENEBODY
F
chr17:37761691-37763551
Island


cg00795812
chr2:242802009
PDCD1.TSS1500
F
chr2:242805752-242806034
N_Shelf


cg14931683
chr17:35872880
DUSP14.GENEBODY
R
chr17:35872722-35873026
Island


cg12097330
chr17:79050221
BAIAP2.GENEBODY
R
chr17:79051892-79052534
N_Shore


cg12517843
chr19:17361126
USHBP1.GENEBODY
F
chr19:17356979-17357500
S_Shelf


cg25216196
chr17:19290520
MFAP4.TSS200
R


cg27051683
chr2:242802069
PDCD1.TSS1500
F
chr2:242805752-242806034
N_Shelf


cg07290310
chr3:125741734
SLC41A3.GENEBODY
R


cg16360668
chr1:19265059
IFFO2.GENEBODY
R


cg12237784
chr7:44187017
GCK.GENEBODY
F
chr7:44184770-44185695
S_Shore


cg00175150
chr1:150486261
ECM1.UTR3
R
chr1:150488036-150488416
N_Shore


cg14292870
chr12:6887543
LAG3.GENEBODY
F


cg16007395
chr1:33231070
KIAA1522.GENEBODY
F


cg24980413
chr5:346987
AHRR.GENEBODY
R
chr5:343449-344535
S_Shelf


cg10827768
chr2:28387339
BRE.GENEBODY
R


cg20340501
chr2:233141525
DIS3L2.GENEBODY
F


cg23271234
chr2:71126275
VAX2.TSS1500
F
chr2:71126720-71129209
N_Shore


cg03162164
chr7:790384
HEATR2.GENEBODY
F
chr7:791984-792238
N_Shore


cg07727884
chr17:19290503
MFAP4.TSS200
R


cg27417749
chr15:69449518
MIR548H4.GENEBODY
R
chr15:69452451-69453939
N_Shelf


cg06603325
chr17:39887725
HAP1.GENEBODY
F
chr17:39889956-39891489
N_Shelf


cg03446876
chr7:129414697
MIR96.TSS200
R
chr7:129418286-129422509
N_Shelf


cg03454775
chr8:2012595
MYOM2.GENEBODY
R


cg09427374
chr2:86095320
ST3GAL5.TSS1500
R


cg10825315
chr14:81425912
TSHR.GENEBODY
R


cg17096191
chr1:162039224
NOS1AP.TSS1500
F
chr1:162039450-162040052
N_Shore


cg19784401
chr11:46457992
AMBRA1.GENEBODY
F


cg04876127
chr1:33618450
TRIM62.GENEBODY
R


cg11312087
chr13:100944053
PCCA.GENEBODY
R


cg14682005
chr6:15337603
JARID2.GENEBODY
R


cg16198315
chr13:72438678
DACH1.GENEBODY
R
chr13:72439362-72440059
N_Shore


cg20721467
chr10:76597927
MYST4.UTR5
F


cg23894058
chr19:51537828
KLK12.GENEBODY
F
chr19:51535218-51535475
S_Shelf


cg00892353
chr8:124247948
C8orf76.GENEBODY
R


cg08472243
chr16:427912
TMEM8A.GENEBODY
F
chr16:426038-426290
S_Shore


cg10135894
chr4:7862655
AFAP1.GENEBODY
F


cg01146614
chr6:159235211
EZR.GENEBODY
F
chr6:159239081-159240775
N_Shelf


cg03470159
chr8:10261798
MSRA.GENEBODY
R
chr8:10261900-10262222
N_Shore


cg04629204
chr1:26348325
EXTL1.EXON1
F


cg15511928
chr1:201895256
LMOD1.GENEBODY
R


cg18482164
chr17:37764118
NEUROD2.UTR5
R
chr17:37764092-37764304
Island


cg23732608
chr20:20180469
C20orf26.GENEBODY
F


cg24355809
chr17:746574
NXN.GENEBODY
R
chr17:744617-744907
S_Shore


cg19595760
chr1:25948511
MAN1C1.GENEBODY
F
chr1:25944099-25944772
S_Shelf


cg08853318
chr17:71089186
SLC39A11.TSS1500
F


cg21706038
chr2:3317693
TSSC1.GENEBODY
R
chr2:3317676-3317935
Island


cg26577529
chr12:52866845
KRT6C.GENEBODY
R


cg01179256
chr12:105141965
CHST11.GENEBODY
F


cg02069944
chr17:79191523
AZI1.GENEBODY
R


cg13409077
chr9:35618528
CD72.TSS200
R
chr9:35616980-35617324
S_Shore


cg13700197
chr9:98221975
PTCH1.GENEBODY
R


cg13867915
chr1:27050039
ARID1A.GENEBODY
F


cg24083274
chr7:121977191
CADPS2.GENEBODY
F


cg05337753
chr17:75373407
SEPT9.UTR5
F
chr17:75368688-75370506
S_Shelf


cg07533819
chr5:71407465
MAP1B.GENEBODY
F
chr5:71402877-71404868
S_Shelf


cg17327404
chr1:33231109
KIAA1522.GENEBODY
R


cg02627403
chr17:73823769
UNC13D.UTR3
R


cg11552585
chr19:3196206
NCLN.GENEBODY
F
chr19:3196188-3196393
Island


cg13406860
chr9:132881336
GPR107.GENEBODY
F


cg17492795
chr1:214637903
PTPN14.GENEBODY
R


cg18590709
chr17:49122713
SPAG9.GENEBODY
R


cg24054871
chr22:45073148
PRR5.UTR5
R


cg13404038
chr9:126123344
CRB2.GENEBODY
F


cg16797751
chr7:105290218
ATXN7L1.GENEBODY
F


cg04607412
chr22:45073157
PRR5.UTR5
R


cg11213150
chr9:129884457
ANGPTL2.UTR5
F


cg19921389
chr3:128780164
GP9.UTR5
R


cg10784542
chr6:169625369
THBS2.GENEBODY
R
chr6:169622297-169622520
S_Shelf


cg21303745
chr17:77959826
TBC1D16.GENEBODY
F


cg06786238
chr1:33231190
KIAA1522.GENEBODY
R


cg09021393
chr7:95849568
MIR591.TSS1500
R


cg14121282
chr9:137268074
RXRA.GENEBODY
F


cg17697739
chr6:1873340
GMDS.GENEBODY
R


cg21885317
chr8:124248094
C8orf76.GENEBODY
F


cg01429256
chr17:17687834
RAI1.UTR5
F
chr17:17685016-17687240
S_Shore


cg02582754
chr6:160327345
MAS1.TSS1500
R


cg07997493
chr17:37761947
NEUROD2.GENEBODY
R
chr17:37761691-37763551
Island


cg21565781
chr12:123892621
SETD8.UTR3
R


cg02381521
chr21:42775934
MX2.GENEBODY
F


cg09768257
chr8:11628346
NEIL2.UTR5
R
chr8:11627091-11627668
S_Shore


cg12205591
chr21:44588552
CRYAA.TSS1500
F
chr21:44590612-44590826
N_Shelf


cg18875674
chr11:73026651
ARHGEF17.GENEBODY
F


cg08958913
chr19:40193890
LGALS14.TSS1500
R


cg20712415
chr3:159570903
SCHIP1.GENEBODY
F


cg24653772
chr7:788989
HEATR2.GENEBODY
F
chr7:791984-792238
N_Shelf


cg10529401
chr1:53587046
SLC1A7.GENEBODY
F


cg13909661
chr12:26386833
SSPN.UTR3
R


cg14388093
chr9:133342842
ASS1.GENEBODY
F


cg27554156
chr12:13248725
GSG1.GENEBODY
F


cg02807008
chr19:1910258
ADAT3.UTR5
R
chr19:1911923-1913406
N_Shore


cg14448919
chr5:435040
AHRR.UTR3
F


cg17873750
chr1:116382984
NHLH2.UTR5
F
chr1:116380359-116382364
S_Shore


cg26844077
chr16:85658855
KIAA0182.UTR5
F
chr16:85658742-85658998
Island


cg26902557
chr11:1585852
DUSP8.GENEBODY
F


cg06479434
chr7:128395929
CALU.GENEBODY
R


cg08811581
chr11:16902852
PLEKHA7.GENEBODY
F


cg08902205
chr16:85658997
KIAA0182.UTR5
F
chr16:85658742-85658998
Island


cg18023842
chr1:160336475
NHLH1.TSS1500
F


cg21448423
chr1:55013956
ACOT11.EXON1
R


cg07923746
chr1:179050803
TOR3A.TSS1500
F
chr1:179051075-179051948
N_Shore


cg10987071
chr2:217276744
SMARCAL1.TSS1500
F
chr2:217277037-217277557
N_Shore


cg07397891
chr1:246582071
SMYD3.GENEBODY
F


cg09997760
chr3:179169556
GNB4.TSS200
R
chr3:179168735-179169593
Island


cg18405786
chr19:18746985
KLHL26.TSS1500
F


cg24852561
chr13:100340080
CLYBL.GENEBODY
F


cg04702527
chr4:139940407
CCRN4L.GENEBODY
F
chr4:139936443-139937428
S_Shelf


cg23994112
chr17:75373457
SEPT9.UTR5
R
chr17:75368688-75370506
S_Shelf


cg05428433
chr16:3614067
NLRC3.GENEBODY
F
chr16:3614316-3614601
N_Shore


cg09138688
chr5:49963801
PARP8.GENEBODY
F
chr5:49962267-49963777
S_Shore


cg11367404
chr4:170180146
SH3RF1.GENEBODY
R


cg15179499
chr5:362529
AHRR.GENEBODY
R
chr5:356570-359526
S_Shelf


cg20782117
chr7:95865631
SLC25A13.GENEBODY
R


cg23296791
chr19:40229766
CLC.TSS1500
F


cg24524634
chr7:2800976
GNA12.GENEBODY
F
chr7:2802440-2802698
N_Shore


cg09309711
chr19:17322661
MYO9B.UTR3
F
chr19:17322471-17322988
Island


cg18254848
chr19:40227949
CLC.GENEBODY
F


cg08157318
chr12:102224140
GNPTAB.GENEBODY
R
chr12:102224262-102224614
N_Shore


cg10833439
chr21:42793818
MX1.UTR5
F
chr21:42792293-42792704
S_Shore


cg12102573
chr17:27924969
ANKRD13B.GENEBODY
F
chr17:27919874-27921105
S_Shelf


cg00756860
chr1:144852047
PDE4DIP.UTR3
R


cg01120953
chr5:149643466
CAMK2A.GENEBODY
R


cg09980085
chr19:40174352
LOC400696.UTR3
F


cg13913247
chr4:141207827
SCOC.UTR5
F


cg17568996
chr22:42828125
NFAM1.GENEBODY
F


cg04571652
chr3:192959762
MGC2889.GENEBODY
F
chr3:192958709-192959373
S_Shore


cg06256596
chr16:66511944
BEAN.GENEBODY
R


cg06772157
chr7:100728711
TRIM56.TSS200
F
chr7:100732088-100732424
N_Shelf


cg23202177
chr1:116383238
NHLH2.UTR5
R
chr1:116380359-116382364
S_Shore


cg16419345
chr17:73976089
ACOX1.TSS1500
R
chr17:73974971-73975731
S_Shore


cg22807608
chr17:17594719
RAI1.UTR5
F
chr17:17597824-17598398
N_Shelf


cg26772172
chr17:77474395
HRNBP3.UTR5
R


cg02566157
chr11:61025815
VWCE.UTR3
R


cg02851203
chr1:54808689
SSBP3.GENEBODY
F


cg08247612
chr1:160336486
NHLH1.TSS1500
F


cg20367923
chr6:169624501
THBS2.GENEBODY
R
chr6:169622297-169622520
S_Shore


cg22460466
chr7:1896154
MAD1L1.GENEBODY
F
chr7:1896090-1896451
Island


cg04530460
chr6:42858550
C6orf226.UTR5
F
chr6:42858169-42858960
Island


cg07424295
chr10:92980030
PCGF5.TSS1500
R
chr10:92980347-92980832
N_Shore


cg09135866
chr19:53238498
ZNF611.TSS200
F
chr19:53237861-53238499
Island


cg22102078
chr6:130182512
C6orf191.TSS200
R


cg04155280
chr17:26692719
SEBOX.GENEBODY
F


cg02997295
chr6:169642301
THBS2.GENEBODY
F
chr6:169641803-169642020
S_Shore


cg08399444
chr12:13248548
GSG1.GENEBODY
F


cg27379887
chr20:1448498
NSFL1C.TSS200
R
chr20:1446936-1447729
S_Shore


cg21831485
chr7:31594014
CCDC129.GENEBODY
F


cg20292636
chr1:204328377
PLEKHA6.UTR5
F


cg23316807
chr19:56628171
ZNF787.UTR5
F
chr19:56631771-56633076
N_Shelf


cg03361664
chr11:3187760
OSBPL5.TSS1500
R
chr11:3186131-3186768
S_Shore


cg11759917
chr17:79655302
HGS.GENEBODY
R
chr17:79655162-79655515
Island


cg17861836
chr17:79202505
C17orf56.UTR3
F


cg19046189
chr19:49316732
HSD17B14.GENEBODY
F
chr19:49315545-49315765
S_Shore


cg25342005
chr1:33648656
TRIM62.TSS1500
R
chr1:33646613-33647878
S_Shore


cg08301181
chr17:73780373
UNK.TSS1500
R
chr17:73780846-73781308
N_Shore


cg23490611
chrX:134475099
ZNF75D.UTR5
R
chrX:134477583-134477999
N_Shelf


cg01157146
chr21:42877638
TMPRSS2.GENEBODY
R
chr21:42878751-42880674
N_Shore


cg03155027
chr3:49907692
CAMKV.TSS1500
F
chr3:49906737-49907482
S_Shore


cg14269510
chr13:47204488
LRCH1.GENEBODY
R


cg18849256
chr12:32309670
BICD1.GENEBODY
F


cg21930140
chr21:42796537
MX1.TSS1500
F
chr21:42798146-42798884
N_Shore


cg22377043
chr15:43809486
MAP1A.TSS1500
F


cg00928231
chr11:67195771
RPS6KB2.TSS200
F
chr11:67195800-67196190
N_Shore


cg04329478
chr19:40169839
LOC400696.TSS200
F


cg05070839
chr8:10261641
MSRA.GENEBODY
F
chr8:10261900-10262222
N_Shore


cg16145834
chr6:33282321
TAPBP.TSS200
R
chr6:33282855-33283196
N_Shore


cg01654446
chr6:33280476
TAPBP.GENEBODY
R
chr6:33281112-33281827
N_Shore


cg15396570
chr1:85931161
DDAH1.TSS1500
F
chr1:85929940-85931168
Island


cg17637107
chr8:20054583
ATP6V1B2.TSS200
R
chr8:20054546-20055027
Island


cg22692213
chr12:133533186
ZNF605.TSS1500
F
chr12:133532642-133532979
S_Shore


cg23596678
chr17:79793000
DYSFIP1.TSS200
R
chr17:79790530-79791553
S_Shore


cg21221712
chr15:86132153
AKAP13.GENEBODY
F


cg26130023
chr18:45453609
SMAD2.UTR5
R
chr18:45456484-45458024
N_Shelf


cg26539941
chr2:220306470
SPEG.GENEBODY
R
chr2:220306855-220307096
N_Shore


cg03466032
chr17:39968802
FKBP10.TSS200
R
chr17:39967407-39968604
S_Shore


cg22862003
chr21:42797588
MX1.TSS1500
F
chr21:42798146-42798884
N_Shore


cg05801879
chr16:84101832
MBTPS1.GENEBODY
F


cg15040499
chr17:35861263
DUSP14.UTR5
R


cg04420932
chr11:67195621
RPS6KB2.TSS1500
F
chr11:67195800-67196190
N_Shore
















TABLE 4







Top 1000 methylation sites associated with the SCLC-P subtype












Methylation Site
Position (GRCh 37)
Gene
Strand
CpG Island Name
Relation to CpG Island





cg05204104
chr2: 235403141
ARL4C.UTR3
R
chr2: 235404502-
N_Shore






235406541


cg02367316
chr7: 39125198
POU6F2.GENEBODY
F


cg10761558
chr1: 54842205
SSBP3.GENEBODY
F


cg00234370
chr1: 36021674
KIAA0319L.UTR5
F
chr1: 36022680-36023834
N_Shore


cg16427983
chr12: 123453858
ABCB9.UTR5
F
chr12: 123450868-
S_Shelf






123451207


cg05942111
chr12: 65044027
RASSF3.GENEBODY
R


cg07120097
chr14: 37257605
SLC25A21.GENEBODY
R


cg10536786
chr1: 7550036
CAMTA1.GENEBODY
R


cg06779248
chr7: 95458266
DYNC1I1.GENEBODY
R


cg18831409
chr6: 10585851
GCNT2.GENEBODY
F


cg05264223
chr15: 70126776
C15orf50.TSS1500
F


cg04765195
chr6: 36209753
PNPLA1.TSS1500
F


cg14795528
chr7: 157451260
PTPRN2.GENEBODY
F
chr7: 157453774-
N_Shelf






157454208


cg04628438
chr6: 10585889
GCNT2.GENEBODY
F


cg26216243
chr6: 49495283
GLYATL3.UTR3
F


cg11964773
chr1: 14924077
KIAA1026.TSS1500
F
chr1: 14924610-14925993
N_Shore


cg13314260
chr5: 141349631
RNF14.UTR5
R
chr5: 141348531-
S_Shore






141349104


cg18314778
chr7: 157468321
PTPRN2.GENEBODY
F


cg18798446
chr12: 103862780
C12orf42.GENEBODY
F


cg09824889
chr3: 121311075
FBXO40.TSS1500
R


cg19239304
chr2: 238621429
LRRFIP1.GENEBODY
R


cg13302670
chr7: 44261293
CAMK2B.GENEBODY
F
chr7: 44259669-44259923
S_Shore


cg12108651
chr7: 158193742
PTPRN2.GENEBODY
F


cg10690467
chr12: 70047752
BEST3.UTR3
R


cg19713140
chr7: 157584994
PTPRN2.GENEBODY
F
chr7: 157586711-
N_Shore






157587112


cg21060736
chr15: 73618666
HCN4.GENEBODY
F


cg13356427
chr1: 6520354
ESPN.UTR3
F
chr1: 6520584-6521955
N_Shore


cg14157527
chr9: 132937709
FREQ.GENEBODY
R
chr9: 132934213-
S_Shelf






132934483


cg07633435
chr5: 152869009
GRIA1.TSS1500
F


cg20129210
chr13: 100547192
CLYBL.UTR3
R
chr13: 100547172-
Island






100547431


cg00970752
chr1: 15711443
FHAD1.GENEBODY
R


cg02746771
chr10: 527872
DIP2C.GENEBODY
R
chr10: 525719-526041
S_Shore


cg21177112
chr12: 63193647
PPM1H.GENEBODY
F
chr12: 63195657-63195909
N_Shelf


cg21781979
chr13: 100547292
CLYBL.UTR3
F
chr13: 100547172-
Island






100547431


cg21963703
chr5: 140350766
PCDHA7.GENEBODY
R
chr5: 140346105-
S_Shelf






140346931


cg18127395
chr7: 95433546
DYNC1I1.UTR5
F


cg22352709
chr3: 195446859
MUC20.TSS1500
R


cg07645286
chr2: 173604634
RAPGEF4.GENEBODY
R
chr2: 173600281-
S_Shelf






173600970


cg06923861
chr11: 117355376
DSCAML1.GENEBODY
F
chr11: 117352691-
S_Shelf






117352961


cg19680850
chr1: 37943106
ZC3H12A.GENEBODY
F
chr1: 37939723-37940650
S_Shelf


cg22226592
chr1: 109439213
GPSM2.GENEBODY
F


cg04479757
chr22: 26951319
MIR548J.TSS200
R


cg07170253
chr12: 48119903
P11.TSS1500
R


cg06400704
chr1: 240256644
FMN2.EXON1
F
chr1: 240254959-
Island






240257063


cg19786648
chr17: 71824806
C17orf54.TSS200
R


cg13284574
chr1: 6519923
ESPN.GENEBODY
F
chr1: 6520584-6521955
N_Shore


cg04415689
chr2: 242128250
ANO7.GENEBODY
F


cg09833249
chr12: 103312819
PAH.TSS1500
R
chr12: 103311040-
S_Shore






103311253


cg11545871
chr6: 33679895
C6orf125.TSS1500
R
chr6: 33679158-33679701
S_Shore


cg22504528
chr22: 26951369
MIR548J.TSS200
F


cg16832421
chr2: 122229878
CLASP1.GENEBODY
F


cg16681516
chr19: 46297285
DMWD.TSS1500
R
chr19: 46295855-46296347
S_Shore


cg12668122
chr3: 133094221
TMEM108.GENEBODY
R


cg26534460
chr2: 215896959
ABCA12.TSS200
F


cg14260458
chr7: 97620123
OCM2.TSS1500
R


cg17852245
chr5: 153688187
GALNT10.GENEBODY
F


cg20141509
chr1: 10781431
CASZ1.UTR5
F


cg25438492
chr6: 33079692
HLA-DPB2.TSS1500
F


cg20831413
chr11: 72460551
ARAP1.UTR5
R
chr11: 72463092-72463717
N_Shelf


cg02394998
chr7: 157334850
PTPRN2.GENEBODY
R


cg12296860
chr11: 46409428
CHRM4.TSS1500
R
chr11: 46410921-46414687
N_Shore


cg21055933
chr14: 64682702
SYNE2.EXON1
F


cg00959749
chr1: 54302681
TMEM48.GENEBODY
F
chr1: 54303758-54304262
N_Shore


cg06665622
chr6: 46293571
RCAN2.TSS200
F


cg11243251
chr6: 36209708
PNPLA1.TSS1500
R


cg05554594
chr17: 80584498
WDR45L.GENEBODY
F


cg02565999
chr13: 95003984
GPC6.GENEBODY
F


cg07065666
chr6: 167034653
RPS6KA2.GENEBODY
R
chr6: 167032330-
S_Shelf






167032582


cg19599803
chr1: 156722676
HDGF.TSS1500
F
chr1: 156720747-
S_Shore






156722069


cg23365482
chr15: 40764195
CHST14.EXON1
F
chr15: 40763162-40764196
Island


cg07920930
chr7: 158381884
PTPRN2.TSS1500
R
chr7: 158379328-
S_Shore






158381221


cg12817389
chr8: 62602522
ASPH.GENEBODY
R


cg15787636
chr17: 80866113
TBCD.GENEBODY
R
chr17: 80863327-80863743
S_Shelf


cg18535456
chr12: 112203801
ALDH2.TSS1500
R
chr12: 112204498-
N_Shore






112204979


cg14703553
chr17: 70663493
SLC39A11.GENEBODY
R


cg19589800
chr12: 93820263
UBE2N.GENEBODY
F


cg07985864
chr1: 10757892
CASZ1.UTR5
R
chr1: 10757891-10758252
Island


cg23261073
chr1: 9880771
CLSTN1.GENEBODY
R
chr1: 9883011-9884667
N_Shelf


cg03732014
chr21: 30676184
BACH1.UTR5
F


cg16595667
chr14: 77567533
KIAA1737.UTR5
F
chr14: 77563965-77564697
S_Shelf


cg27630771
chr1: 150533123
ADAMTSL4.UTR3
R
chr1: 150534075-
N_Shore






150534301


cg07610192
chr2: 131130423
PTPN18.GENEBODY
R
chr2: 131129718-
Island






131130511


cg15055890
chr3: 11747650
VGLL4.UTR5
R
chr3: 11746577-11746824
S_Shore


cg21146273
chr5: 152869193
GRIA1.TSS1500
F


cg14677615
chr17: 27315628
SEZ6.GENEBODY
R
chr17: 27312969-27313283
S_Shelf


cg14946113
chr22: 44220872
SULT4A1.UTR3
F


cg17930201
chr1: 155828174
SYT11.TSS1500
R
chr1: 155829109-
N_Shore






155829431


cg06286135
chr7: 157511479
PTPRN2.GENEBODY
F


cg03442858
chr1: 14924535
KIAA1026.TSS1500
F
chr1: 14924610-14925993
N_Shore


cg07686441
chr15: 52570517
MIR1266.TSS1500
R


cg18090068
chr3: 55693316
C3orf51.GENEBODY
R


cg14278148
chr9: 114663626
UGCG.GENEBODY
F
chr9: 114658618-
S_Shelf






114659773


cg12575928
chr11: 22687660
GAS2.TSS1500
R
chr11: 22688285-22688617
N_Shore


cg25368586
chr13: 111561018
ANKRD10.GENEBODY
F


cg08976117
chr3: 57064983
ARHGEF3.GENEBODY
R


cg27569829
chr18: 60984485
BCL2.GENEBODY
R
chr18: 60985503-60985741
N_Shore


cg15472885
chr3: 71056608
FOXP1.GENEBODY
R


cg14962159
chr13: 37441585
SMAD9.GENEBODY
F


cg14398557
chr20: 1095840
PSMF1.UTR5
R
chr20: 1099078-1099561
N_Shelf


cg10288437
chr6: 158432894
SYNJ2.GENEBODY
F


cg20976787
chr6: 43064460
PTK7.GENEBODY
R


cg10294732
chr4: 41614397
LIMCH1.GENEBODY
F


cg19314992
chr11: 76614479
ACER3.GENEBODY
R


cg16125375
chr5: 146298512
PPP2R2B.UTR5
R


cg13663667
chr19: 4180236
SIRT6.GENEBODY
F
chr19: 4182259-4182803
N_Shelf


cg02711899
chr6: 42410890
TRERF1.UTR5
R


cg13127741
chr20: 31331821
COMMD7.TSS200
F
chr20: 31330957-31331410
S_Shore


cg08352439
chr7: 55637123
VOPP1.GENEBODY
F
chr7: 55639277-55640599
N_Shelf


cg04528038
chr16: 21171097
TMEM159.UTR5
F
chr16: 21169810-21170278
S_Shore


cg06342490
chr2: 42795193
MTA3.TSS1500
F
chr2: 42795847-42796230
N_Shore


cg21574244
chr15: 42568411
GANC.GENEBODY
F
chr15: 42565452-42565791
S_Shelf


cg00551589
chr16: 2626391
PDPK1.GENEBODY
R
chr16: 2627134-2627399
N_Shore


cg17461336
chr7: 99441559
CYP3A43.GENEBODY
R


cg26207423
chr8: 28787952
HMBOX1.UTR5
R


cg01489441
chr16: 1764111
MAPK8IP3.GENEBODY
R


cg27434467
chr10: 101686326
NCRNA00093.TSS1500
F


cg26245086
chr4: 87860957
AFF1.UTR5
F
chr4: 87855873-87857204
S_Shelf


cg07696516
chr4: 41614958
LIMCH1.EXON1
F


cg16457351
chr5: 176297315
UNC5A.GENEBODY
R
chr5: 176296541-
S_Shore






176296933


cg01372366
chr11: 48041783
PTPRJ.GENEBODY
F


cg16039867
chr1: 47023134
MKNK1.GENEBODY
R


cg23615892
chr1: 215825505
USH2A.GENEBODY
R


cg13763232
chr3: 14443428
SLC6A6.TSS1500
R
chr3: 14443629-14444577
N_Shore


cg00957901
chr4: 41614842
LIMCH1.TSS200
R


cg01794926
chr15: 92470387
SLCO3A1.GENEBODY
R


cg16544220
chr6: 33095030
HLA-DPB2.GENEBODY
F


cg00718444
chr8: 145685564
CYHR1.GENEBODY
F
chr8: 145687389-
N_Shore






145687880


cg03227338
chr11: 46998965
C11orf49.GENEBODY
F


cg13491737
chr13: 111295728
CARS2.GENEBODY
R
chr13: 111294675-
S_Shore






111294900


cg21579399
chr2: 11890700
LPIN1.UTR5
F
chr2: 11886249-11887207
S_Shelf


cg00249974
chr1: 156254149
TMEM79.EXON1
R


cg15585294
chr11: 22687641
GAS2.TSS1500
R
chr11: 22688285-22688617
N_Shore


cg22340762
chr1: 183823538
RGL1.GENEBODY
F


cg00408605
chr8: 141466079
TRAPPC9.UTR5
R
chr8: 141467218-
N_Shore






141467927


cg00600617
chr6: 107221887
LOC553137.GENEBODY
F


cg00618183
chr17: 75143600
SEC14L1.GENEBODY
R


cg00625110
chr16: 53741731
FTO.GENEBODY
R
chr16: 53737617-53738235
S_Shelf


cg00703885
chr2: 128440247
LIMS2.TSS1500
F


cg00704369
chr7: 81996559
CACNA2D1.GENEBODY
R


cg00706536
chr17: 40609826
ATP6VOA1.TSS1500
R
chr17: 40610746-40611032
N_Shore


cg01149239
chr3: 196746085
MFI2.UTR3
F


cg01307483
chr7: 129254604
NRF1.UTR5
F
chr7: 129251237-
S_Shelf






129252441


cg01580044
chr1: 114300656
PHTF1.GENEBODY
R
chr1: 114301514-
N_Shore






114302272


cg01626895
chr12: 116425790
MED13L.GENEBODY
R


cg01653080
chr14: 104205041
PPP1R13B.GENEBODY
F
chr14: 104205070-
N_Shore






104205329


cg01715088
chr1: 6520772
ESPN.UTR3
R
chr1: 6520584-6521955
Island


cg02220284
chr3: 71013485
FOXP1.GENEBODY
F


cg02253499
chr3: 12602046
MKRN2.GENEBODY
F
chr3: 12598391-12599051
S_Shelf


cg02330721
chr16: 1764231
MAPK8IP3.GENEBODY
R


cg02519218
chr12: 133424286
CHFR.GENEBODY
R


cg02793948
chr11: 68095662
LRP5.GENEBODY
F


cg03075214
chr11: 64867914
C11orf2.GENEBODY
R
chr11: 64863698-64863980
S_Shelf


cg03147598
chr2: 131104160
IMP4.UTR3
F
chr2: 131099469-
S_Shelf






131100863


cg03264729
chr11: 72347339
PDE2A.GENEBODY
R


cg03803789
chr11: 111854003
DIXDC1.GENEBODY
R


cg04390667
chr11: 46624867
HARBI1.UTR3
R


cg05001389
chr9: 135853034
GFI1B.TSS1500
R


cg05661060
chr1: 44074454
PTPRF.GENEBODY
F
chr1: 44070892-44071142
S_Shelf


cg06206957
chr7: 33080615
NT5C3.TSS200
R


cg06604199
chr20: 31331973
COMMD7.TSS200
R
chr20: 31330957-31331410
S_Shore


cg06669752
chr5: 138534431
SIL1.TSS1500
R
chr5: 138533870-
S_Shore






138534113


cg06832246
chr11: 93224210
C11orf75.UTR5
R


cg06839854
chr2: 10536115
HPCAL1.UTR5
R


cg07205154
chr1: 176147105
RFWD2.GENEBODY
R


cg07313835
chr1: 167342724
POU2F1.GENEBODY
F


cg07699978
chr12: 63194001
PPM1H.GENEBODY
R
chr12: 63195657-63195909
N_Shore


cg07859138
chrX: 118751995
SEPT6.UTR3
F


cg07956003
chr7: 95433460
DYNC1I1.UTR5
F


cg08101329
chr17: 4884631
CAMTA2.GENEBODY
R


cg08238265
chr14: 64682912
SYNE2.EXON1
R


cg08781755
chr2: 44172074
LRPPRC.GENEBODY
F


cg09169413
chr12: 48103670
P11.UTR3
F
chr12: 48099317-48099905
S_Shelf


cg10386431
chr1: 77879031
AK5.GENEBODY
F


cg10887937
chr12: 112203795
ALDH2.TSS1500
R
chr12: 112204498-
N_Shore






112204979


cg11019743
chr6: 168267395
MLLT4.GENEBODY
F


cg11132582
chr1: 167217689
POU2F1.UTR5
F


cg11447040
chr20: 37667339
DHX35.UTR3
R


cg11701604
chr11: 36095771
LDLRAD3.GENEBODY
F


cg13146674
chr11: 68095623
LRP5.GENEBODY
R


cg13556548
chr1: 226187876
C1orf55.TSS1500
R
chr1: 226186803-
S_Shore






226187336


cg13578134
chr15: 75081572
CSK.UTR5
R


cg13619387
chr9: 92050313
SEMA4D.UTR5
R


cg13676816
chr9: 91976972
SEMA4D.UTR3
R


cg14211075
chr9: 135818481
TSC1.UTR5
R
chr9: 135819526-
N_Shore






135820529


cg14301030
chr10: 264920
ZMYND11.GENEBODY
R


cg14302130
chr6: 33032830
HLA-DPA1.UTR3
R


cg14457284
chr9: 135852984
GFI1B.TSS1500
R


cg14701925
chr3: 128980811
COPG.GENEBODY
F


cg14817765
chr20: 2444494
SNORD119.TSS1500
F


cg15337905
chr7: 150807508
AGAP3.GENEBODY
R


cg15425670
chr2: 42461109
EML4.GENEBODY
F


cg15724534
chr2: 211018363
C2orf67.GENEBODY
R


cg15873449
chr18: 12885569
PTPN2.TSS1500
F
chr18: 12883285-12884578
S_Shore


cg16318349
chr1: 154917307
PBXIP1.UTR3
R


cg16691863
chr1: 28848173
SNHG3-RCC1.GENEBODY
R
chr1: 28844653-28845293
S_Shelf


cg17308493
chr10: 30634469
MTPAP.GENEBODY
F
chr10: 30637961-30638279
N_Shelf


cg17355865
chr11: 76887139
MYO7A.GENEBODY
R
chr11: 76890783-76890986
N_Shelf


cg17758792
chr21: 37620038
DOPEY2.GENEBODY
F
chr21: 37617467-37617872
S_Shelf


cg18455249
chr4: 56813898
CEP135.TSS1500
R
chr4: 56814800-56815511
N_Shore


cg18872426
chr19: 38874037
PSMD8.UTR3
F
chr19: 38876070-38876332
N_Shelf


cg19125791
chr2: 240265915
HDAC4.GENEBODY
F


cg19506380
chr8: 98740612
MTDH.UTR3
F


cg19918623
chr7: 132661002
CHCHD3.GENEBODY
R


cg20059682
chr12: 52201821
SCN8A.UTR3
F


cg20467658
chr15: 89933347
LOC254559.GENEBODY
R


cg20497631
chr8: 8647440
MFHAS1.GENEBODY
R


cg20664313
chr12: 133071297
FBRSL1.GENEBODY
R
chr12: 133073397-
N_Shelf






133073632


cg20716489
chr3: 195591877
TNK2.GENEBODY
R
chr3: 195594836-
N_Shelf






195595494


cg21232015
chr12: 133424221
CHFR.GENEBODY
R


cg21289124
chr22: 26951249
TPST2.UTR5
R


cg21535670
chr8: 140798600
TRAPPC9.GENEBODY
F


cg21877565
chr1: 156461550
MEF2D.UTR5
F


cg21927971
chr2: 17837235
VSNL1.UTR3
R


cg21940081
chr2: 131103235
IMP4.GENEBODY
R
chr2: 131099469-
S_Shelf






131100863


cg22542731
chr2: 128440274
LIMS2.TSS1500
F


cg23396732
chr20: 31332170
COMMD7.TSS1500
F
chr20: 31330957-31331410
S_Shore


cg24136932
chr8: 22281979
SLC39A14.GENEBODY
R


cg24440131
chr1: 26880207
MIR1976.TSS1500
R


cg24495350
chr15: 72651198
HEXA.GENEBODY
F


cg24677222
chr3: 140102647
CLSTN2.GENEBODY
F


cg25601286
chr2: 169408033
LASS6.GENEBODY
R


cg25874150
chr10: 34941561
PARD3.GENEBODY
R


cg26224018
chr1: 64942153
CACHD1.GENEBODY
F


cg26542660
chr4: 56813860
CEP135.TSS1500
R
chr4: 56814800-56815511
N_Shore


cg26579713
chr15: 65701865
IGDCC4.GENEBODY
F


cg26797073
chr2: 131129811
PTPN18.GENEBODY
F
chr2: 131129718-
Island






131130511


cg27053763
chr5: 180653815
TRIM41.GENEBODY
R
chr5: 180650099-
S_Shelf






180650679


cg27222157
chr11: 66382978
RBM14.TSS1500
F
chr11: 66383571-66385047
N_Shore


cg27254046
chr6: 57272398
PRIM2.GENEBODY
F


cg00854324
chr16: 69941269
WWP2.GENEBODY
R


cg01099470
chr2: 131103656
IMP4.GENEBODY
F
chr2: 131099469-
S_Shelf






131100863


cg02428072
chr3: 169900473
PHC3.TSS1500
F
chr3: 169898946-
S_Shore






169899626


cg03152913
chr2: 178975712
RBM45.TSS1500
R
chr2: 178977078-
N_Shore






178977828


cg03356778
chr11: 120110544
POU2F3.TSS1500
F
chr11: 120110497-
Island






120110719


cg04976330
chr1: 31480640
PUM1.GENEBODY
R


cg05399330
chr1: 55464530
BSND.TSS200
R
chr1: 55462688-55463010
S_Shore


cg06912922
chr19: 12708229
ZNF490.GENEBODY
F
chr19: 12707696-12708114
S_Shore


cg07993367
chr7: 149568778
ATP6V0E2.TSS1500
R
chr7: 149570366-
N_Shore






149571272


cg08313040
chr6: 33092243
HLA-DPB2.GENEBODY
F


cg08320861
chr6: 33095982
HLA-DPB2.GENEBODY
R


cg08651894
chr1: 154832235
KCNN3.GENEBODY
R


cg09417011
chr1: 54842404
SSBP3.GENEBODY
F


cg09735908
chr16: 88770558
RNF166.GENEBODY
F
chr16: 88772237-88773195
N_Shore


cg10833114
chr12: 72246108
MRS2P2.TSS1500
F


cg12022772
chr2: 131130468
PTPN18.GENEBODY
R
chr2: 131129718-
Island






131130511


cg12598235
chr15: 89921182
LOC254559.TSS200
R
chr15: 89920793-89922768
Island


cg15109449
chr1: 12363259
VPS13D.GENEBODY
F


cg15618336
chr12: 52182759
SCN8A.GENEBODY
R


cg15939973
chr17: 76419841
DNAH17.UTR3
F
chr17: 76421441-76421766
N_Shore


cg17301216
chr15: 89920348
LOC254559.TSS1500
R
chr15: 89920793-89922768
N_Shore


cg17730176
chr17: 27404126
TIAF1.TSS1500
R
chr17: 27406753-27408059
N_Shelf


cg18942985
chr2: 128523110
WDR33.GENEBODY
R


cg19465165
chr2: 131130103
PTPN18.GENEBODY
R
chr2: 131129718-
Island






131130511


cg19856701
chr17: 29549474
NF1.UTR3
F


cg20886791
chr6: 33096055
HLA-DPB2.GENEBODY
R


cg22158248
chr12: 112204136
ALDH2.TSS1500
R
chr12: 112204498-
N_Shore






112204979


cg26306289
chr7: 33080571
NT5C3.TSS200
F


cg27627524
chr8: 131325625
ASAP1.GENEBODY
R


cg00848167
chr15: 89921898
LOC254559.GENEBODY
F
chr15: 89920793-89922768
Island


cg01227084
chr19: 2774520
SGTA.UTR5
R
chr19: 2774196-2774550
Island


cg01685549
chr6: 33092097
HLA-DPB2.GENEBODY
R


cg01767053
chr16: 85678884
KIAA0182.UTR5
R
chr16: 85674843-85675192
S_Shelf


cg01951712
chr6: 33081535
HLA-DPB2.GENEBODY
F
chr6: 33084740-33084995
N_Shelf


cg02388468
chr6: 33095664
HLA-DPB2.GENEBODY
F


cg02470179
chr3: 31580476
STT3B.GENEBODY
F


cg03766449
chr15: 89920918
LOC254559.TSS1500
F
chr15: 89920793-89922768
Island


cg03917138
chr17: 70120182
SOX9.GENEBODY
F
chr17: 70120139-70120442
Island


cg04918708
chr1: 204057900
SOX13.UTR5
F


cg05427639
chr7: 33080496
NT5C3.EXON1
R


cg06517794
chr1: 78180274
USP33.GENEBODY
R


cg07586345
chr19: 2774332
SGTA.UTR5
R
chr19: 2774196-2774550
Island


cg09787021
chr1: 25988486
MAN1C1.GENEBODY
R


cg09825327
chr1: 211503219
TRAF5.UTR5
F
chr1: 211500151-
S_Shelf






211500636


cg10327769
chr17: 43340243
LOC100133991.GENEBODY
F
chr17: 43339124-43339832
S_Shore


cg10657965
chr7: 101888125
CUX1.GENEBODY
R
chr7: 101891665-
N_Shelf






101892634


cg11786476
chr6: 33096738
HLA-DPB2.GENEBODY
R


cg12406391
chr1: 6520194
ESPN.GENEBODY
F
chr1: 6520584-6521955
N_Shore


cg12873454
chr1: 14924611
KIAA1026.TSS1500
R
chr1: 14924610-14925993
Island


cg13077784
chr1: 201706363
NAV1.GENEBODY
R
chr1: 201708787-
N_Shelf






201709429


cg13977526
chr9: 32384244
ACO1.TSS1500
F
chr9: 32384420-32384911
N_Shore


cg15019001
chr6: 33096303
HLA-DPB2.GENEBODY
R


cg15826519
chr1: 19808575
CAPZB.GENEBODY
F
chr1: 19811703-19812644
N_Shelf


cg16072780
chr11: 93453897
SCARNA9.TSS1500
F


cg16205850
chr15: 75118021
LMAN1L.UTR3
R


cg18109571
chr6: 127835189
C6orf174.GENEBODY
F
chr6: 127835928-
N_Shore






127836255


cg18198143
chr6: 33094306
HLA-DPB2.GENEBODY
F


cg18474502
chr10: 124777194
ACADSB.GENEBODY
R


cg18680328
chr10: 123868970
TACC2.GENEBODY
R
chr10: 123872119-
N_Shelf






123873462


cg19046783
chr7: 99382086
CYP3A4.TSS1500
R


cg20314331
chr2: 131129567
PTPN18.GENEBODY
R
chr2: 131129718-
N_Shore






131130511


cg20567355
chr8: 52754434
PCMTD1.GENEBODY
R


cg21516291
chr20: 44979100
SLC35C2.GENEBODY
F


cg21955534
chrX: 15525514
BMX.EXON1
F


cg22052010
chr20: 33541934
GSS.UTR5
R
chr20: 33543082-33543846
N_Shore


cg22888311
chr12: 80076443
PAWR.GENEBODY
F


cg23538755
chr19: 2774549
SGTA.UTR5
F
chr19: 2774196-2774550
Island


cg24156613
chrX: 39950501
BCOR.UTR5
R
chrX: 39950899-39951665
N_Shore


cg24180219
chr10: 105239190
CALHM3.TSS200
R


cg25064331
chr7: 33080500
NT5C3.EXON1
R


cg25474399
chr18: 3067624
MYOM1.GENEBODY
F
chr18: 3067297-3067533
S_Shore


cg25759507
chr11: 12008553
DKK3.GENEBODY
R


cg26086731
chr3: 169900468
PHC3.TSS1500
F
chr3: 169898946-
S_Shore






169899626


cg26469011
chr10: 75886930
AP3M1.GENEBODY
F


cg26536240
chr16: 89509760
ANKRD11.UTR5
R


cg00350405
chr2: 128244940
IWS1.GENEBODY
F


cg01541650
chr6: 157505968
ARID1B.GENEBODY
R


cg02061660
chr5: 110088130
SLC25A46.GENEBODY
F


cg02380236
chr15: 22383188
OR4N4.EXON1
F


cg03233656
chr2: 65214625
SLC1A4.TSS1500
F
chr2: 65215598-65217212
N_Shore


cg04824189
chr7: 80142634
GNAT3.TSS1500
F


cg05009111
chr20: 58520201
C20orf177.UTR3
R


cg05366160
chr6: 33039481
HLA-DPA1.GENEBODY
F


cg06614640
chr17: 80826697
TBCD.GENEBODY
R
chr17: 80827970-80828316
N_Shore


cg09142647
chr16: 75674568
KARS.GENEBODY
R


cg10094078
chr19: 1467925
APC2.GENEBODY
F
chr19: 1465206-1471241
Island


cg10297701
chr6: 32972902
HLA-DOA.UTR3
F
chr6: 32975684-32975926
N_Shelf


cg10604002
chr2: 131130131
PTPN18.GENEBODY
R
chr2: 131129718-
Island






131130511


cg10725390
chr2: 66743000
MEIS1.GENEBODY
F


cg12733040
chr22: 17303493
XKR3.TSS1500
F


cg12748948
chr1: 22106295
USP48.GENEBODY
F
chr1: 22109129-22110261
N_Shelf


cg12815916
chr2: 131114432
PTPN18.GENEBODY
F
chr2: 131113090-
S_Shore






131114277


cg13726789
chr8: 37678323
GPR124.GENEBODY
F


cg13922121
chr11: 19575262
NAV2.GENEBODY
F


cg15214229
chr20: 35275274
SLA2.TSS1500
R


cg16296829
chr1: 154832535
KCNN3.TSS200
R


cg16431810
chr7: 2420339
EIF3B.UTR3
F
chr7: 2419808-2420340
Island


cg18451156
chr12: 133424373
CHFR.GENEBODY
R


cg18963065
chrX: 15525321
BMX.UTR5
F


cg21049501
chr17: 70120411
SOX9.GENEBODY
F
chr17: 70120139-70120442
Island


cg21121843
chr4: 3203982
HTT.GENEBODY
R


cg21156320
chr12: 56112820
BLOC1S1.GENEBODY
R
chr12: 56109798-56110298
S_Shelf


cg04403809
chr20: 44686493
SLC12A5.UTR3
R
chr20: 44685771-44687610
Island


cg00538021
chr16: 12192263
SNX29.GENEBODY
R


cg00712146
chr3: 65340538
MAGI1.UTR3
R
chr3: 65342203-65342884
N_Shore


cg01249653
chr6: 33095755
HLA-DPB2.GENEBODY
F


cg03212228
chr19: 38395481
WDR87.UTR5
F
chr19: 38397003-38398165
N_Shore


cg03387092
chr3: 123493248
MYLK.GENEBODY
R


cg04117530
chr1: 226187852
C1orf55.TSS1500
R
chr1: 226186803-
S_Shore






226187336


cg04256886
chr2: 25603640
DTNB.GENEBODY
R
chr2: 25599676-25599895
S_Shelf


cg04351807
chr11: 36013639
LDLRAD3.GENEBODY
R


cg04478905
chr21: 37915091
CLDN14.TSS200
F


cg04998498
chr11: 113725687
USP28.GENEBODY
F


cg05613017
chr12: 65589446
LEMD3.GENEBODY
F


cg06234051
chr17: 70120541
SOX9.UTR3
F
chr17: 70116274-70119998
S_Shore


cg06532924
chr1: 247268238
ZNF669.TSS1500
F
chr1: 247267179-
S_Shore






247267884


cg07069844
chr19: 1617027
TCF3.GENEBODY
F
chr19: 1615202-1615812
S_Shore


cg07202461
chr18: 19406765
MIB1.GENEBODY
F


cg07813851
chr1: 7466976
CAMTA1.GENEBODY
F


cg08088222
chr12: 122070432
ORAI1.GENEBODY
F


cg08948637
chr20: 62614493
PRPF6.GENEBODY
R
chr20: 62612300-62612787
S_Shore


cg10004079
chr17: 26372530
NLK.GENEBODY
R
chr17: 26368586-26369133
S_Shelf


cg10735599
chr6: 33081024
HLA-DPB2.GENEBODY
F
chr6: 33084740-33084995
N_Shelf


cg10932086
chr14: 90041348
PRO1768.TSS1500
F


cg12255995
chr19: 1132537
SBNO2.GENEBODY
R


cg12555369
chr10: 105153066
USMG5.UTR5
R
chr10: 105155820-
N_Shelf






105156484


cg12577003
chr7: 2261337
MAD1L1.GENEBODY
R


cg12582616
chr6: 15427489
JARID2.GENEBODY
F


cg13058710
chr17: 70119609
SOX9.GENEBODY
F
chr17: 70116274-70119998
Island


cg13362033
chr1: 7018949
CAMTA1.GENEBODY
F
chr1: 7022001-7022308
N_Shelf


cg13726166
chr17: 27403888
TIAF1.TSS1500
F
chr17: 27406753-27408059
N_Shelf


cg13738075
chr13: 114793125
RASA3.GENEBODY
R


cg14373068
chr11: 1537765
HCCA2.GENEBODY
F
chr11: 1536729-1536953
S_Shore


cg14521421
chr11: 8862019
ST5.UTR5
R


cg14762436
chr7: 24917750
OSBPL3.GENEBODY
F


cg17223866
chr1: 44794158
ERI3.GENEBODY
F


cg18236734
chr3: 183817931
HTR3E.TSS200
F


cg18714586
chr13: 30831499
KATNAL1.GENEBODY
R


cg19232395
chr11: 8550221
STK33.UTR5
R


cg19251161
chr10: 106094166
ITPRIP.TSS1500
R
chr10: 106097595-
N_Shelf






106098556


cg19490899
chr6: 52855923
GSTA4.GENEBODY
R
chr6: 52859565-52859767
N_Shelf


cg19644145
chr7: 21488742
SP4.GENEBODY
F


cg20288892
chr7: 82072332
CACNA2D1.GENEBODY
R
chr7: 82072021-82073520
Island


cg20706496
chr6: 112084071
FYN.UTR5
R


cg22235258
chr11: 34675402
EHF.GENEBODY
F


cg22736267
chr7: 148841524
ZNF398.UTR5
F
chr7: 148844254-
N_Shelf






148845556


cg23025804
chr10: 29811659
SVIL.GENEBODY
F


cg23794671
chr6: 32977580
HLA-DOA.TSS200
F
chr6: 32975684-32975926
S_Shore


cg23998903
chr2: 209048830
C2orf80.GENEBODY
F


cg24223075
chr11: 119137279
CBL.GENEBODY
F


cg24321688
chr19: 39393347
NFKBIB.GENEBODY
F
chr19: 39395881-39396106
N_Shelf


cg24904278
chr4: 3514709
LRPAP1.GENEBODY
F
chr4: 3514537-3514848
Island


cg24918798
chr2: 103432687
TMEM182.UTR3
R


cg25380514
chr3: 169900418
PHC3.TSS1500
F
chr3: 169898946-
S_Shore






169899626


cg25649889
chr2: 171196296
MYO3B.GENEBODY
F


cg25681122
chr3: 194832600
C3orf21.GENEBODY
F


cg25848827
chr1: 7550111
CAMTA1.GENEBODY
R


cg25977504
chr1: 247979157
OR14A16.TSS200
R


cg00425764
chr16: 15949616
MYH11.UTR5
R
chr16: 15950839-15951266
N_Shore


cg00863378
chr16: 56549757
BBS2.GENEBODY
R
chr16: 56553529-56554075
N_Shelf


cg00946598
chr1: 44117093
KDM4A.UTR5
F
chr1: 44115616-44116309
S_Shore


cg01140395
chr15: 52570565
MIR1266.TSS1500
F


cg01418162
chr1: 204891567
NFASC.UTR5
R


cg01708014
chr14: 51299002
NIN.TSS1500
R
chr14: 51296727-51298477
S_Shore


cg01772439
chr5: 149012102
FLJ41603.UTR3
R


cg01859360
chr17: 26990458
SUPT6H.UTR5
R
chr17: 26988721-26989391
S_Shore


cg01891209
chr1: 44401222
ARTN.TSS1500
R
chr1: 44401757-44402423
N_Shore


cg02362718
chr11: 133942581
JAM3.GENEBODY
F
chr11: 133938850-
S_Shelf






133939681


cg02632809
chr7: 5336811
SLC29A4.GENEBODY
R
chr7: 5336513-5336894
Island


cg04022912
chr16: 24864984
SLC5A11.UTR5
F


cg04153082
chr8: 48325740
KIAA0146.GENEBODY
F


cg04272613
chr14: 59721173
DAAM1.UTR5
F


cg04694619
chr2: 242127759
ANO7.TSS200
F


cg05995528
chr6: 33036495
HLA-DPA1.GENEBODY
F


cg06821199
chr4: 779230
CPLX1.UTR3
F
chr4: 778661-780592
Island


cg06985721
chr1: 55464653
BSND.EXON1
F
chr1: 55462688-55463010
S_Shore


cg08961287
chr15: 89919993
LOC254559.TSS1500
F
chr15: 89920793-89922768
N_Shore


cg09561830
chr13: 100007116
UBAC2.GENEBODY
R


cg10042298
chr11: 78024311
GAB2.GENEBODY
R


cg10471574
chr17: 70120318
SOX9.GENEBODY
F
chr17: 70120139-70120442
Island


cg10803321
chr1: 50629523
ELAVL4.GENEBODY
R


cg10818986
chr1: 248083146
OR2T8.TSS1500
R


cg11131599
chr1: 204224211
PLEKHA6.GENEBODY
F
chr1: 204226544-
N_Shelf






204226908


cg12338214
chr10: 133783113
BNIP3.GENEBODY
R


cg12499542
chr12: 53808156
SP1.UTR3
R


cg12832726
chr11: 68096165
LRP5.GENEBODY
F


cg13375479
chr7: 133984347
SLC35B4.GENEBODY
F


cg13551330
chr9: 32388149
ACO1.UTR5
R
chr9: 32384420-32384911
S_Shelf


cg13696135
chr12: 49396782
PRKAG1.GENEBODY
R
chr12: 49393139-49393361
S_Shelf


cg14200678
chr9: 123380343
MEGF9.GENEBODY
F


cg14373797
chr6: 33053576
HLA-DPB1.GENEBODY
R


cg14880894
chr4: 78697859
CNOT6L.GENEBODY
R


cg15661715
chr7: 151401947
PRKAG2.GENEBODY
F


cg15955522
chr5: 143553445
KCTD16.UTR5
R
chr5: 143549939-
S_Shelf






143550333


cg16083838
chr11: 2889809
KCNQ1DN.TSS1500
R
chr11: 2890388-2891337
N_Shore


cg16189995
chr2: 226330770
KIAA1486.GENEBODY
R


cg17491228
chr11: 64476089
NRXN2.GENEBODY
F
chr11: 64478843-64479598
N_Shelf


cg17851748
chr12: 83264140
TMTC2.GENEBODY
R


cg18063824
chr4: 54075042
SCFD2.GENEBODY
F


cg18282011
chr1: 1590447
CDK11B.GENEBODY
F
chr1: 1590073-1590942
Island


cg19083007
chr6: 46293862
RCAN2.TSS1500
R


cg19740679
chr1: 21930180
RAP1GAP.GENEBODY
R
chr1: 21930179-21930380
Island


cg20535805
chr19: 18420735
LSM4.GENEBODY
F
chr19: 18420489-18420736
Island


cg20643029
chr21: 37915044
CLDN14.TSS200
F


cg21039196
chr6: 71435620
SMAP1.GENEBODY
F


cg21221516
chr3: 183950129
VWA5B2.GENEBODY
F
chr3: 183947040-
S_Shore






183948801


cg21350778
chr17: 64297603
PRKCA.TSS1500
R
chr17: 64298047-64299617
N_Shore


cg23034373
chr21: 37915354
CLDN14.UTR5
F


cg23200572
chr6: 33096501
HLA-DPB2.GENEBODY
R


cg24008634
chr10: 13694895
FRMD4A.GENEBODY
R
chr10: 13698562-13699540
N_Shelf


cg24401199
chr19: 3159786
GNA15.GENEBODY
F
chr19: 3162841-3163161
N_Shelf


cg24677302
chr14: 75922163
JDP2.GENEBODY
R


cg24987745
chr2: 17819167
VSNL1.GENEBODY
R


cg25119261
chr6: 33081351
HLA-DPB2.GENEBODY
R
chr6: 33084740-33084995
N_Shelf


cg25243171
chr2: 23914356
KLHL29.GENEBODY
R
chr2: 23913308-23913569
S_Shore


cg26886855
chr8: 10694831
PINX1.GENEBODY
R
chr8: 10697016-10697634
N_Shelf


cg26949694
chr11: 27742060
BDNF.GENEBODY
R
chr11: 27742059-27742273
Island


cg27636594
chr7: 38767436
VPS41.GENEBODY
R


cg01208614
chr5: 141031443
FCHSD1.TSS1500
R
chr5: 141030918-
S_Shore






141031177


cg02389877
chr15: 68583600
FEM1B.UTR3
F


cg02882004
chr2: 201334663
SPATS2L.GENEBODY
R


cg04077303
chr1: 236308094
GPR137B.GENEBODY
R
chr1: 236305534-
S_Shore






236306674


cg04576847
chr17: 12623611
MYOCD.GENEBODY
R


cg06879534
chr4: 39447437
KLB.GENEBODY
F
chr4: 39448184-39449054
N_Shore


cg07010146
chr10: 105239205
CALHM3.TSS1500
R


cg07304186
chr6: 38112278
ZFAND3.GENEBODY
R


cg08759770
chr12: 51849767
SLC4A8.GENEBODY
F


cg13339454
chr2: 242127690
ANO7.TSS1500
F


cg14080888
chr9: 130712990
FAM102A.UTR5
F


cg18477771
chr11: 120195466
TMEM136.TSS1500
F
chr11: 120195805-
N_Shore






120196372


cg19377250
chr7: 100463206
SLC12A9.GENEBODY
F
chr7: 100463758-
N_Shore






100464146


cg20272287
chr17: 19247905
MIR1180.TSS200
F
chr17: 19247785-19248069
Island


cg21265278
chr1: 179057067
TOR3A.GENEBODY
F


cg23541975
chr17: 75143184
SEC14L1.GENEBODY
R


cg00552822
chr15: 22368443
LOC727924.GENEBODY
R


cg00796611
chr1: 206603444
SRGAP2.GENEBODY
R


cg01367339
chr3: 44962718
ZDHHC3.GENEBODY
R


cg01638185
chr17: 64530027
PRKCA.GENEBODY
R


cg01668281
chr21: 37915281
CLDN14.UTR5
R


cg01715699
chr13: 99209655
STK24.GENEBODY
R


cg01854491
chr8: 144815021
FAM83H.UTR5
F
chr8: 144815203-
N_Shore






144816518


cg02246992
chr17: 29158363
ATAD5.TSS1500
F
chr17: 29158878-29159423
N_Shore


cg02370478
chrX: 106241676
MORC4.GENEBODY
R
chrX: 106242506-
N_Shore






106243593


cg02544829
chr8: 95385408
RAD54B.GENEBODY
F


cg03332109
chr11: 126360468
KIRREL3.GENEBODY
F


cg04086197
chr14: 104205071
PPP1R13B.GENEBODY
R
chr14: 104205070-
Island






104205329


cg04236786
chr8: 41580903
ANK1.GENEBODY
R
chr8: 41583135-41583524
N_Shelf


cg04920416
chr17: 35336293
AATF.GENEBODY
R


cg05490757
chr17: 77130342
HRNBP3.UTR5
F
chr17: 77133927-77134175
N_Shelf


cg06927775
chr17: 40609423
ATP6VOA1.TSS1500
R
chr17: 40610746-40611032
N_Shore


cg07481360
chr3: 196902551
DLG1.GENEBODY
F


cg07535740
chr19: 5915494
CAPS.UTR3
F
chr19: 5915007-5915301
S_Shore


cg08707617
chrX: 39944352
BCOR.UTR5
R
chrX: 39942756-39943419
S_Shore


cg08760402
chr6: 33036486
HLA-DPA1.GENEBODY
R


cg09002351
chr16: 75204945
ZFP1.UTR3
F


cg09203240
chr11: 68115891
LRP5.GENEBODY
R
chr11: 68115317-68115726
S_Shore


cg10674511
chrX: 78003091
LPAR4.TSS200
F


cg10808783
chr19: 1467921
APC2.GENEBODY
F
chr19: 1465206-1471241
Island


cg11336987
chr3: 123974913
KALRN.GENEBODY
F


cg12700788
chr17: 72348160
KIF19.GENEBODY
R
chr17: 72347924-72348322
Island


cg12892471
chr12: 50616779
LIMA1.GENEBODY
F


cg13356324
chr1: 228332502
GUK1.UTR5
R
chr1: 228327508-
S_Shelf






228328560


cg14353201
chr11: 67448395
ALDH3B2.UTR5
F


cg15770046
chr19: 35764710
USF2.GENEBODY
F
chr19: 35760457-35760865
S_Shelf


cg16712103
chr1: 193150499
B3GALT2.GENEBODY
F


cg16831185
chr17: 29158530
ATAD5.TSS1500
F
chr17: 29158878-29159423
N_Shore


cg17219729
chr1: 36937845
CSF3R.GENEBODY
F


cg17582782
chr15: 57592438
LOC283663.TSS200
F


cg17649671
chr10: 89298596
MINPP1.GENEBODY
F


cg18106482
chr11: 2680314
KCNQ1.GENEBODY
R


cg18993757
chr17: 4889754
CAMTA2.UTR5
F
chr17: 4890282-4890991
N_Shore


cg19113599
chr15: 99683042
TTC23.GENEBODY
R


cg19296405
chr19: 18368483
KIAA1683.GENEBODY
R
chr19: 18368482-18368911
Island


cg19533977
chr17: 57719682
CLTC.GENEBODY
F


cg19601328
chr17: 43368729
MAP3K14.UTR5
R


cg19909036
chr15: 90294776
MESP1.TSS1500
F
chr15: 90293221-90294733
S_Shore


cg20664654
chrX: 153169465
AVPR2.TSS1500
R


cg22057240
chr5: 6755843
POLS.UTR3
R
chr5: 6755104-6755387
S_Shore


cg22675922
chr11: 2889840
KCNQ1DN.TSS1500
R
chr11: 2890388-2891337
N_Shore


cg24051242
chr11: 68096138
LRP5.GENEBODY
R


cg24063043
chr17: 64567021
PRKCA.GENEBODY
R


cg24420432
chr7: 101518619
CUX1.GENEBODY
F


cg27050612
chr17: 46133198
NFE2L1.GENEBODY
F
chr17: 46136649-46136969
N_Shelf


cg27064928
chrX: 146996911
ASFMR1.GENEBODY
F
chrX: 146993091-
S_Shelf






146994200


cg01966522
chr3: 126236504
UROC1.EXON1
R


cg04619304
chr12: 24434537
SOX5.UTR5
R


cg05043047
chr8: 144583910
ZC3H3.GENEBODY
R


cg05169160
chr2: 178484487
TTC30A.TSS1500
R
chr2: 178483233-
S_Shore






178483783


cg05733361
chr15: 85524456
PDE8A.TSS1500
R
chr15: 85523512-85525865
Island


cg06895124
chr8: 141588750
EIF2C2.GENEBODY
R


cg07178896
chr16: 50238554
PAPD5.GENEBODY
F


cg09038267
chr10: 104524861
C10orf26.GENEBODY
F


cg10369242
chr12: 52625486
KRT7.TSS1500
R
chr12: 52626793-52627577
N_Shore


cg11678118
chr6: 122935372
PKIB.UTR5
F
chr6: 122931153-
S_Shelf






122931705


cg12100006
chr11: 35964190
LDLRAD3.TSS1500
R
chr11: 35965642-35966454
N_Shore


cg12738079
chrX: 153169469
AVPR2.TSS1500
R


cg12745145
chr7: 2261452
MAD1L1.GENEBODY
F


cg13259357
chr3: 191109928
CCDC50.UTR3
F


cg14356799
chr6: 33044345
HLA-DPB1.GENEBODY
R


cg14981137
chr5: 50678697
ISL1.TSS1500
R
chr5: 50678632-50679375
Island


cg16235962
chr11: 118754507
CXCR5.TSS200
F


cg18907656
chr8: 30888925
PURG.GENEBODY
F


cg19407960
chr6: 33094829
HLA-DPB2.GENEBODY
F


cg20738500
chr15: 89921156
LOC254559.TSS200
F
chr15: 89920793-89922768
Island


cg20851325
chrX: 153169432
AVPR2.TSS1500
F


cg21211730
chr19: 45279770
CBLC.TSS1500
F
chr19: 45281133-45281355
N_Shore


cg21608489
chr19: 42637137
POU2F2.TSS1500
R
chr19: 42637277-42637684
N_Shore


cg22338118
chr7: 94536003
PPP1R9A.TSS1500
F
chr7: 94536849-94537477
N_Shore


cg24644448
chr2: 114383268
RPL23AP7.GENEBODY
R
chr2: 114384589-
N_Shore






114385133


cg25694790
chr20: 17582752
DSTN.GENEBODY
F


cg26067647
chr19: 1420404
DAZAP1.GENEBODY
F
chr19: 1419751-1420405
Island


cg26643856
chr6: 32977349
HLA-DOA.EXON1
R
chr6: 32975684-32975926
S_Shore


cg27500983
chr20: 34700201
EPB41L1.TSS200
R


cg00166343
chr17: 29150100
CRLF3.GENEBODY
R
chr17: 29151481-29151901
N_Shore


cg01091565
chr15: 90294762
MESP1.TSS1500
F
chr15: 90293221-90294733
S_Shore


cg01755009
chr1: 247978690
OR14A16.EXON1
F


cg02347367
chr6: 109250017
ARMC2.GENEBODY
R


cg02397571
chr8: 28175463
PNOC.UTR5
F


cg06544652
chr1: 248006259
OR11L1.TSS1500
R


cg08097973
chr11: 71793051
LRTOMT.UTR5
R
chr11: 71791385-71791960
S_Shore


cg08822075
chr7: 26193607
NFE2L3.GENEBODY
R
chr7: 26191794-26192757
S_Shore


cg10057033
chr8: 41737893
ANK1.GENEBODY
F
chr8: 41733535-41733911
S_Shelf


cg11301657
chr12: 3749918
EFCAB4B.GENEBODY
R


cg11437465
chr6: 33036958
HLA-DPA1.GENEBODY
F


cg12704098
chr3: 56838665
ARHGEF3.GENEBODY
F
chr3: 56835650-56836210
S_Shelf


cg15642209
chr17: 66290505
ARSG.UTR5
R
chr17: 66286541-66288532
S_Shore


cg15841865
chr7: 143173551
TAS2R41.TSS1500
F


cg16027403
chr1: 247978791
OR14A16.EXON1
F


cg16527552
chr19: 42816045
TMEM145.TSS1500
R
chr19: 42817412-42818038
N_Shore


cg17138415
chr12: 107259568
RIC8B.GENEBODY
R


cg17395184
chr15: 42750462
ZFP106.TSS1500
R


cg19333963
chr19: 1467979
APC2.GENEBODY
F
chr19: 1465206-1471241
Island


cg19494588
chr5: 146195103
PPP2R2B.GENEBODY
R


cg22392325
chr1: 7049418
CAMTA1.GENEBODY
F


cg23746600
chr6: 160403181
IGF2R.GENEBODY
F


cg25019648
chr17: 72353261
BTBD17.GENEBODY
R
chr17: 72352827-72353798
Island


cg25444002
chr13: 102520143
FGF14.GENEBODY
R


cg27121870
chr11: 134257030
B3GAT1.GENEBODY
R
chr11: 134257428-
N_Shore






134257631


cg27319536
chr5: 146260901
PPP2R2B.UTR5
R
chr5: 146257346-
S_Shelf






146258575


cg27382459
chr2: 145237379
ZEB2.GENEBODY
F


cg27639080
chr12: 49960363
MCRS1.GENEBODY
R
chr12: 49961630-49962219
N_Shore


cg00762029
chr4: 185317438
IRF2.GENEBODY
R


cg01217406
chr15: 23013480
NIPA2.GENEBODY
R


cg01220513
chrX: 19902129
SH3KBP1.GENEBODY
F
chrX: 19905027-19906557
N_Shelf


cg01620165
chr12: 113530915
DTX1.GENEBODY
R
chr12: 113530914-
Island






113531476


cg01708377
chr6: 1686746
GMDS.GENEBODY
R


cg02291620
chr1: 233365140
PCNXL2.GENEBODY
F


cg02394186
chr1: 6088550
KCNAB2.UTR5
F
chr1: 6086244-6086494
S_Shelf


cg03389720
chr16: 8780048
ABAT.UTR5
R


cg04021887
chr2: 10566989
HPCAL1.UTR3
R
chr2: 10566889-10567148
Island


cg05058976
chr16: 3637956
BTBD12.GENEBODY
R
chr16: 3639092-3639306
N_Shore


cg05157251
chr18: 57566460
PMAIP1.TSS1500
R
chr18: 57566866-57567723
N_Shore


cg05407550
chrX: 154250784
F8.EXON1
R


cg05621843
chr9: 97806397
C9orf3.GENEBODY
F
chr9: 97807450-97807694
N_Shore


cg07038822
chr11: 125830798
CDON.UTR3
F


cg07507418
chr6: 42372284
TRERF1.UTR5
R


cg07716663
chr19: 42636625
POU2F2.UTR5
F
chr19: 42637277-42637684
N_Shore


cg07768372
chr5: 14509008
TRIO.UTR3
F


cg07849009
chr7: 105663410
FLJ23834.GENEBODY
F


cg07960154
chr17: 37760198
NEUROD2.UTR3
F
chr17: 37761691-37763551
N_Shore


cg08438392
chr2: 27708644
IFT172.GENEBODY
R
chr2: 27712554-27712842
N_Shelf


cg09016768
chr11: 118982033
C2CD2L.GENEBODY
F
chr11: 118977878-
S_Shelf






118978785


cg09640202
chr2: 131101440
IMP4.GENEBODY
R
chr2: 131099469-
S_Shore






131100863


cg10090761
chr19: 1468466
APC2.GENEBODY
F
chr19: 1465206-1471241
Island


cg11650039
chrX: 15525325
BMX.UTR5
R


cg12110887
chr19: 11096925
SMARCA4.GENEBODY
R
chr19: 11098395-11098609
N_Shore


cg12184624
chr10: 105239164
CALHM3.TSS200
F


cg12426293
chr18: 8612540
RAB12.GENEBODY
F
chr18: 8608763-8610370
S_Shelf


cg12858166
chr6: 33033176
HLA-DPA1.UTR3
R


cg13027851
chr2: 102433793
MAP4K4.GENEBODY
F


cg13403121
chr7: 148963719
ZNF783.GENEBODY
R
chr7: 148958858-
S_Shelf






148959891


cg15076824
chr1: 159685185
CRP.TSS1500
F


cg15795819
chr8: 39328433
ADAM3A.GENEBODY
R


cg16175713
chr6: 46617172
CYP39A1.GENEBODY
F
chr6: 46620541-46621189
N_Shelf


cg16430279
chr1: 1266504
TAS1R3.TSS1500
F
chr1: 1267085-1267286
N_Shore


cg18457491
chr10: 104829517
CNNM2.GENEBODY
R


cg18586851
chr20: 31332353
COMMD7.TSS1500
R
chr20: 31330957-31331410
S_Shore


cg19237600
chr7: 99564474
AZGP1.UTR3
R


cg19305488
chr19: 1468359
APC2.GENEBODY
F
chr19: 1465206-1471241
Island


cg19861842
chr8: 22855745
RHOBTB2.GENEBODY
R
chr8: 22856800-22857728
N_Shore


cg20058937
chr7: 5336543
SLC29A4.GENEBODY
R
chr7: 5336513-5336894
Island


cg20668952
chr15: 75082885
CSK.UTR5
F


cg20927312
chr3: 14443473
SLC6A6.TSS1500
R
chr3: 14443629-14444577
N_Shore


cg21702431
chr17: 19617084
SLC47A2.GENEBODY
R
chr17: 19617083-19617424
Island


cg23750365
chr6: 33043072
HLA-DPB1.TSS1500
F


cg24532476
chr12: 133424566
CHFR.GENEBODY
F


cg24686845
chr12: 94698752
PLXNC1.GENEBODY
F


cg25052933
chr6: 33052888
HLA-DPB1.GENEBODY
F


cg25087423
chr11: 118754535
CXCR5.TSS200
R


cg25255988
chr11: 75428927
MOGAT2.TSS200
R


cg25901444
chr7: 5336713
SLC29A4.GENEBODY
R
chr7: 5336513-5336894
Island


cg26074140
chr1: 44401309
ARTN.TSS1500
F
chr1: 44401757-44402423
N_Shore


cg26300785
chr10: 81075492
ZMIZ1.UTR3
F


cg26385743
chr2: 131101463
IMP4.GENEBODY
R
chr2: 131099469-
S_Shore






131100863


cg26455386
chr17: 16999983
MPRIP.GENEBODY
R


cg26576576
chr1: 214627705
PTPN14.GENEBODY
R


cg27134386
chr4: 46392485
GABRA2.TSS1500
R
chr4: 46391903-46392572
Island


cg27407935
chr17: 17723235
SREBF1.GENEBODY
F
chr17: 17726855-17727282
N_Shelf


cg00457932
chr15: 28145216
OCA2.GENEBODY
F
chr15: 28147925-28148465
N_Shelf


cg03402235
chr15: 42749336
ZFP106.EXON1
F


cg04245374
chr1: 168150977
TIPRL.GENEBODY
F
chr1: 168147963-
S_Shelf






168148637


cg05571310
chr17: 72350354
KIF19.GENEBODY
R
chr17: 72350346-72350711
Island


cg06253072
chr6: 33679850
C6orf125.TSS1500
F
chr6: 33679158-33679701
S_Shore


cg07209550
chr5: 79070077
CMYA5.GENEBODY
R


cg09888186
chr1: 183782195
RGL1.GENEBODY
R


cg10294240
chr14: 96686415
BDKRB2.UTR5
R


cg12194594
chr13: 113426250
ATP11A.GENEBODY
R
chr13: 113424898-
S_Shore






113425105


cg13432241
chr4: 154389285
KIAA0922.GENEBODY
F
chr4: 154386834-
S_Shore






154388183


cg17890764
chr3: 52864816
ITIH4.TSS200
R


cg18491744
chr8: 41580834
ANK1.GENEBODY
F
chr8: 41583135-41583524
N_Shelf


cg20069765
chr6: 33036464
HLA-DPA1.GENEBODY
R


cg21670451
chr5: 139781334
ANKHD1.TSS200
F
chr5: 139780307-
Island






139782108


cg23272088
chr11: 2504813
KCNQ1.GENEBODY
R


cg25227866
chr17: 71489530
SDK2.GENEBODY
R


cg00093829
chr10: 6247101
PFKFB3.GENEBODY
F
chr10: 6242975-6246457
S_Shore


cg01027750
chr19: 42636639
POU2F2.TSS200
F
chr19: 42637277-42637684
N_Shore


cg02782292
chr4: 144433846
SMARCA5.TSS1500
F
chr4: 144434249-
N_Shore






144435343


cg03040622
chr7: 5536937
MIR589.TSS1500
F
chr7: 5539957-5541567
N_Shelf


cg03101058
chr17: 71258936
CPSF4L.TSS1500
R


ce03499581
chr15: 78384868
SH2D7.TSS200
R


cg04398759
chr1: 203101066
ADORA1.GENEBODY
R
chr1: 203097233-
S_Shelf






203097496


cg04502517
chr20: 62564156
DNAJC5.UTR3
R
chr20: 62562545-62562862
S_Shore


cg04908961
chr13: 92003278
MIR17HG.GENEBODY
F
chr13: 91999541-92001441
S_Shore


cg05030172
chr19: 2078510
MOBKL2A.GENEBODY
F
chr19: 2078162-2078511
Island


cg05137443
chr6: 33094069
HLA-DPB2.GENEBODY
F


cg05299486
chr17: 40609380
ATP6VOA1.TSS1500
R
chr17: 40610746-40611032
N_Shore


cg05451388
chr3: 183817678
HTR3E.TSS1500
F


cg05887270
chr1: 26129627
SEPN1.GENEBODY
R


cg07097026
chr6: 44257942
TCTE1.UTR5
F
chr6: 44253897-44254150
S_Shelf


cg07151747
chr2: 158977473
UPP2.GENEBODY
F


cg07992044
chr11: 68096049
LRP5.GENEBODY
F


cg08402572
chr2: 97510201
ANKRD23.TSS1500
F


cg10097316
chr12: 7966784
SLC2A14.UTR3
R


cg11356398
chr10: 133783182
BNIP3.GENEBODY
F


cg11891522
chr5: 61605247
KIF2A.GENEBODY
F
chr5: 61601617-61602930
S_Shelf


cg12131414
chr17: 72352968
BTBD17.GENEBODY
F
chr17: 72352827-72353798
Island


cg12524428
chr5: 146268595
PPP2R2B.UTR5
F


cg12674490
chr6: 31587470
BAT2.TSS1500
R
chr6: 31587779-31589024
N_Shore


cg12738981
chr1: 155828357
SYT11.TSS1500
R
chr1: 155829109-
N_Shore






155829431


cg13187009
chr20: 55965497
RBM38.TSS1500
R
chr20: 55966212-55966964
N_Shore


cg13277337
chr2: 240265810
HDAC4.GENEBODY
R


cg13594542
chr9: 138850547
UBAC1.GENEBODY
R
chr9: 138852639-
N_Shelf






138853439


cg13925678
chr19: 3522946
FZR1.UTR5
F


cg14095761
chr9: 35713238
TLN1.GENEBODY
F


cg14168316
chr9: 127642782
GOLGA1.UTR3
R


cg14173476
chr17: 19190476
EPN2.UTR5
F


cg15031661
chr1: 240256603
FMN2.EXON1
F
chr1: 240254959-
Island






240257063


cg15844109
chrX: 78003205
LPAR4.EXON1
F


cg16054907
chr22: 50706065
MAPK11.GENEBODY
R
chr22: 50705406-50706553
Island


cg16518986
chr7: 157511420
PTPRN2.GENEBODY
F


cg17297045
chr12: 125581343
AACS.GENEBODY
R
chr12: 125578348-
S_Shelf






125578588


cg17547928
chr4: 737930
PCGF3.GENEBODY
F
chr4: 738424-741517
N_Shore


cg17846127
chr15: 89940505
LOC254559.GENEBODY
R
chr15: 89942592-89943853
N_Shelf


cg18183642
chr1: 44497694
SLC6A9.TSS1500
F
chr1: 44495629-44497112
S_Shore


cg18315680
chr1: 154833117
KCNN3.GENEBODY
R


cg18927185
chr6: 33091634
HLA-DPB2.GENEBODY
F


cg19062108
chr12: 57630834
NDUFA4L2.GENEBODY
R
chr12: 57631932-57634578
N_Shore


cg19482842
chr2: 16790314
FAM49A.UTR5
F


cg19710814
chr6: 33091596
HLA-DPB2.GENEBODY
R


cg19995654
chr12: 66628777
IRAK3.GENEBODY
R


cg20574732
chr7: 158277801
PTPRN2.GENEBODY
F
chr7: 158277603-
Island






158278027


cg20643991
chr5: 121690136
SNCAIP.UTR5
F


cg21542666
chr1: 248005715
OR11L1.TSS1500
R


cg21570811
chr4: 3362574
RGS12.GENEBODY
F
chr4: 3365194-3365415
N_Shelf


cg21751684
chr15: 89920887
LOC254559.TSS1500
R
chr15: 89920793-89922768
Island


cg21830221
chr1: 42334284
HIVEP3.UTR5
F


cg22646210
chr11: 72380726
PDE2A.TSS1500
F


cg23105863
chr14: 101011318
BEGAIN.GENEBODY
F
chr14: 101012840-
N_Shore






101013117


cg23331433
chr6: 33039606
HLA-DPA1.GENEBODY
F


cg23502492
chr17: 42394379
RUNDC3A.GENEBODY
R
chr17: 42392323-42393079
S_Shore


cg24940706
chr19: 1648682
TCF3.GENEBODY
F
chr19: 1646117-1646713
S_Shore


cg25057035
chr6: 33053889
HLA-DPB1.GENEBODY
R


cg25516633
chr8: 101315846
RNF19A.TSS1500
F


cg26013412
chr1: 247094486
AHCTF1.GENEBODY
R
chr1: 247094485-
Island






247095667


cg26164712
chr11: 118754565
CXCR5.UTR5
F


cg26283963
chr7: 29330752
CHN2.GENEBODY
F


cg26603629
chr7: 2752217
AMZ1.GENEBODY
F


cg27184903
chr15: 29285727
APBA2.UTR5
F


cg27191457
chr15: 69105133
ANP32A.GENEBODY
F


cg27244524
chr3: 38494523
LOC100128640.GENEBODY
F
chr3: 38495088-38497151
N_Shore


cg27661104
chr2: 232645033
PDE6D.GENEBODY
F
chr2: 232645313-
N_Shore






232646505


cg02982614
chr11: 89391479
FOLH1B.TSS1500
R


cg12348588
chr17: 72352897
BTBD17.GENEBODY
R
chr17: 72352827-72353798
Island


cg13993358
chr5: 176304275
UNC5A.GENEBODY
R
chr5: 176304965-
N_Shore






176305166


cg19567891
chr15: 89921083
LOC254559.TSS200
F
chr15: 89920793-89922768
Island


cg20371142
chr20: 17295221
PCSK2.GENEBODY
F
chr20: 17296125-17296531
N_Shore


cg20745419
chr1: 151696417
C1orf230.GENEBODY
F
chr1: 151693991-
S_Shelf






151694282


cg24953213
chr5: 172140
PLEKHG4B.GENEBODY
R
chr5: 169578-169798
S_Shelf


cg00088251
chr1: 1449754
ATAD3A.UTR5
R
chr1: 1446878-1448205
S_Shore


cg00481644
chr15: 89921158
LOC254559.TSS200
F
chr15: 89920793-89922768
Island


cg00547530
chr16: 3559687
CLUAP1.GENEBODY
F


cg00863271
chr17: 76798776
USP36.GENEBODY
F
chr17: 76798154-76798461
S_Shore


cg01011403
chr4: 56500362
NMU.GENEBODY
F
chr4: 56501912-56502523
N_Shore


cg01476047
chr10: 73974007
ASCC1.UTR5
F
chr10: 73975671-73976115
N_Shore


cg01477971
chr2: 103405951
TMEM182.GENEBODY
R


cg01663696
chr12: 7942817
NANOG.GENEBODY
F


cg01833923
chr17: 47286719
GNGT2.EXON1
R


cg02140508
chr12: 4659038
RAD51AP1.GENEBODY
F


cg02478836
chr22: 47510037
TBC1D22A.GENEBODY
F
chr22: 47513202-47513585
N_Shelf


cg03366884
chr17: 8844506
PIK3R5.UTR5
R


cg03368665
chr11: 89819442
UBTFL1.EXON1
R


cg03450107
chr1: 41980863
HIVEP3.GENEBODY
R
chr1: 41981788-41982043
N_Shore


cg04625873
chr11: 118754530
CXCR5.TSS200
F


cg05244974
chr17: 8798734
PIK3R5.GENEBODY
R


cg05680240
chr6: 31765195
LSM2.UTR3
R
chr6: 31763240-31763905
S_Shore


cg05766510
chr7: 157454062
PTPRN2.GENEBODY
R
chr7: 157453774-
Island






157454208


cg05845757
chr1: 36039885
TFAP2E.GENEBODY
F
chr1: 36038927-36040051
Island


cg05913474
chr8: 144815204
FAM83H.UTR5
R
chr8: 144815203-
Island






144816518


cg05926586
chr15: 74592786
CCDC33.GENEBODY
R


cg06788504
chr6: 32974517
HLA-DOA.UTR3
F
chr6: 32975684-32975926
N_Shore


cg06860422
chr16: 788079
NARFL.GENEBODY
F
chr16: 787070-787327
S_Shore


cg07159802
chr1: 247921568
OR1C1.EXON1
F


cg07344019
chr15: 69337685
MIR548H4.GENEBODY
F


cg07470396
chr19: 54697539
TSEN34.UTR3
F
chr19: 54693034-54695497
S_Shelf


cg08192337
chr12: 124982002
NCOR2.UTR5
F


cg08210506
chr14: 81456824
TSHR.GENEBODY
F


cg08797864
chr3: 185531258
IGF2BP2.GENEBODY
R


cg08822746
chr22: 31321152
C22orf27.GENEBODY
R
chr22: 31318228-31318489
S_Shelf


cg08856378
chr17: 560590
VPS53.GENEBODY
R


cg09274040
chr10: 134994455
KNDC1.GENEBODY
R
chr10: 134996318-
N_Shore






134996548


cg09506037
chr2: 134180560
NCKAP5.GENEBODY
F


cg09900440
chr6: 33033312
HLA-DPA1.UTR3
R


cg09910067
chr7: 157357758
PTPRN2.GENEBODY
R
chr7: 157361512-
N_Shelf






157361805


cg10572969
chr11: 13690188
FAR1.TSS200
F
chr11: 13689588-13690724
Island


cg11156873
chr5: 1491579
LPCAT1.GENEBODY
R
chr5: 1489799-1490071
S_Shore


cg11514462
chr11: 121001293
TECTA.GENEBODY
F
chr11: 120998386-
S_Shelf






120998886


cg12192566
chr5: 140011377
CD14.UTR3
F
chr5: 140011482-
N_Shore






140012739


cg13337413
chr17: 10728324
PIRT.UTR3
F


cg13607138
chr20: 33539306
GSS.GENEBODY
R
chr20: 33543082-33543846
N_Shelf


cg14150071
chr1: 33545982
ADC.TSS1500
F
chr1: 33546524-33547243
N_Shore


cg14286660
chr7: 1050071
C7orf50.GENEBODY
F
chr7: 1048921-1049124
S_Shore


cg14826031
chr11: 75376361
MAP6.GENEBODY
F
chr11: 75378416-75379882
N_Shelf


cg15005255
chr19: 18368728
KIAA1683.GENEBODY
F
chr19: 18368482-18368911
Island


cg15344504
chr3: 31677078
STT3B.GENEBODY
F


cg17045790
chr12: 6128269
VWF.GENEBODY
F


cg17771737
chr19: 20150505
ZNF682.TSS1500
R
chr19: 20149855-20150175
S_Shore


cg18554789
chr7: 139432178
HIPK2.GENEBODY
F


cg18559249
chr17: 37760173
NEUROD2.UTR3
F
chr17: 37761691-37763551
N_Shore


cg19402335
chr1: 159410002
OR10J1.EXON1
R


cg20484653
chr1: 204955033
NFASC.GENEBODY
F
chr1: 204950982-
S_Shelf






204951210


cg21045306
chr12: 57637925
STAC3.GENEBODY
R
chr12: 57636557-57637673
S_Shore


cg21378690
chrX: 71694534
HDAC8.UTR3
F


cg21745287
chr12: 123464511
ARL6IP4.TSS1500
R
chr12: 123464820-
N_Shore






123465972


cg22931292
chr11: 17765568
KCNC1.GENEBODY
R


cg24627621
chr6: 42109176
C6orf132.GENEBODY
R
chr6: 42109904-42110361
N_Shore


cg24931632
chr1: 47899667
MGC12982.GENEBODY
F
chr1: 47899661-47900385
Island


cg25199552
chr1: 23350054
KDM1A.GENEBODY
R
chr1: 23345814-23346677
S_Shelf


cg25647583
chr15: 91427184
FES.TSS1500
F
chr15: 91427540-91427905
N_Shore


cg25716623
chr15: 89921845
LOC254559.GENEBODY
F
chr15: 89920793-89922768
Island


cg26009944
chr1: 52210504
OSBPL9.UTR5
F


cg26355228
chr2: 3260869
TSSC1.GENEBODY
F


cg26406292
chr7: 75292248
HIP1.GENEBODY
F


cg27113326
chr7: 157454068
PTPRN2.GENEBODY
R
chr7: 157453774-
Island






157454208


cg00108992
chr16: 12192325
SNX29.GENEBODY
R


cg00168967
chr8: 62505560
ASPH.GENEBODY
R


cg00256675
chr4: 802962
CPLX1.GENEBODY
R
chr4: 798538-798984
S_Shelf


cg00572387
chr20: 1472914
SIRPB2.TSS1500
R


cg00582579
chr8: 135533786
ZFAT.GENEBODY
R


cg00629585
chr9: 135853992
GFI1B.TSS200
R


cg00869989
chr19: 2774197
SGTA.UTR5
F
chr19: 2774196-2774550
Island


cg00957480
chr17: 10728755
PIRT.GENEBODY
R


cg01120761
chr12: 7903170
CLEC4C.TSS1500
R


cg01953456
chr3: 183817976
HTR3E.UTR5
R


cg02264238
chr3: 51426377
MANF.GENEBODY
R
chr3: 51428412-51429625
N_Shelf


cg02308914
chr3: 129290549
PLXND1.GENEBODY
R


cg02590486
chr12: 499376
KDM5A.TSS1500
R
chr12: 498098-498920
S_Shore


cg02882755
chr6: 34100963
GRM4.EXON1
R


cg02915544
chr11: 89392829
FOLH1B.UTR5
R


cg03231860
chr11: 128893940
RICS.EXON1
F


cg03243669
chr7: 1931776
MAD1L1.GENEBODY
F


cg03465847
chrX: 40594937
MED14.TSS200
F
chrX: 40594515-40595457
Island


cg03766174
chr16: 81547907
CMIP.GENEBODY
F


cg04428805
chr17: 65239522
HELZ.UTR5
R
chr17: 65240725-65242498
N_Shore


cg04756594
chr16: 24857601
SLC5A11.EXON1
R


cg05647891
chr4: 153346037
FBXW7.UTR5
F


cg05794927
chr1: 248059252
OR2W3.EXON1
F


cg05938958
chr1: 248224887
OR2L3.EXON1
F


cg06222979
chr18: 14543469
POTEC.UTR5
F


cg06531741
chr11: 113775450
HTR3B.TSS200
F


cg06969933
chr16: 88099740
BANP.GENEBODY
F
chr16: 88101473-88101911
N_Shore


cg07474672
chr6: 90142171
ANKRD6.TSS1500
F
chr6: 90142751-90143635
N_Shore


cg07825294
chr19: 1415757
DAZAP1.GENEBODY
R
chr19: 1419751-1420405
N_Shelf


cg07915189
chr19: 7688621
XAB2.GENEBODY
R
chr19: 7688620-7688832
Island


cg08468599
chr1: 2182126
SKI.GENEBODY
F


cg08813944
chr17: 71258589
CPSF4L.TSS1500
F


cg08917933
chr1: 19615303
AKR7A3.TSS200
R
chr1: 19614998-19615660
Island


cg08927102
chr1: 1050110
C1orf159.UTR5
F
chr1: 1050515-1050830
N_Shore


cg09419176
chr7: 157670705
PTPRN2.GENEBODY
R
chr7: 157669879-
S_Shore






157670095


cg09445097
chr9: 130186736
ZNF79.UTR5
R
chr9: 130186276-
Island






130187160


cg09867656
chr1: 76550508
ST6GALNAC3.GENEBODY
R


cg09934892
chr16: 3559551
CLUAP1.GENEBODY
F


cg10100117
chr1: 179843111
TOR1AIP2.UTR5
R
chr1: 179846879-
N_Shelf






179847106


cg10329874
chr11: 66621442
PC.GENEBODY
R
chr11: 66623620-66626614
N_Shelf


cg10409230
chr17: 40318360
KCNH4.GENEBODY
F


cg10487770
chr5: 57879443
RAB3C.GENEBODY
R
chr5: 57878725-57879177
S_Shore


cg10719970
chr6: 41529932
FOXP4.UTR5
R
chr6: 41528266-41528900
S_Shore


cg11375616
chr21: 47287017
PCBP3.GENEBODY
R
chr21: 47287012-47287426
Island


cg11397606
chr1: 67151389
SGIP1.GENEBODY
R


cg11661493
chr17: 74423978
UBE20.GENEBODY
F


cg11866943
chr3: 52529351
STAB1.TSS200
F


cg12426652
chr21: 37915056
CLDN14.TSS200
F


cg12991341
chr8: 109800287
TMEM74.TSS1500
F
chr8: 109799429-
S_Shore






109799847


cg13372513
chr7: 158177056
PTPRN2.GENEBODY
F


cg13534791
chr9: 35042344
C9orf131.EXON1
F


cg13995599
chr13: 113426270
ATP11A.GENEBODY
R
chr13: 113424898-
S_Shore






113425105


cg14274019
chr9: 134184504
PPAPDC3.UTR3
R
chr9: 134183330-
S_Shore






134183613


cg14879948
chr5: 1394576
SLC6A3.UTR3
F


cg15147833
chr1: 247921672
OR1C1.EXON1
R


cg15617023
chr13: 40113248
LHFP.GENEBODY
R


cg15871371
chr3: 71274624
FOXP1.UTR5
F


cg15871766
chr12: 52365222
ACVR1B.GENEBODY
F


cg16748694
chr10: 126754386
CTBP2.UTR5
R


cg16895672
chr10: 34470745
PARD3.GENEBODY
R


cg16983282
chr17: 9871831
GAS7.GENEBODY
R


cg17013166
chr22: 30961151
GAL3ST1.TSS1500
R


cg17135722
chr20: 17295815
PCSK2.GENEBODY
R
chr20: 17296125-17296531
N_Shore


cg17179826
chr1: 204946032
NFASC.UTR3
R


cg17707347
chr1: 234614967
TARBP1.TSS200
F
chr1: 234613936-
Island






234614972


cg17810765
chr2: 242127836
ANO7.TSS200
R


cg17912283
chr17: 72350487
KIF19.GENEBODY
F
chr17: 72350346-72350711
Island


cg18502477
chr11: 57946199
OR9Q1.UTR5
F


cg18812946
chrX: 153140985
L1CAM.GENEBODY
F


cg18861762
chr2: 242127852
ANO7.TSS200
F


cg19148404
chr3: 14443444
SLC6A6.TSS1500
F
chr3: 14443629-14444577
N_Shore


cg19273683
chr1: 21656047
ECE1.GENEBODY
R


cg19325793
chr6: 33082165
HLA-DPB2.GENEBODY
F
chr6: 33084740-33084995
N_Shelf


cg19393755
chr17: 71258101
CPSF4L.TSS200
F


cg19405329
chr15: 49440632
COPS2.GENEBODY
F


cg19547192
chr7: 158059976
PTPRN2.GENEBODY
R
chr7: 158060894-
N_Shore






158061100


cg19606462
chr5: 7827964
ADCY2.UTR3
R


cg20682981
chr17: 1962627
HIC1.UTR3
F
chr17: 1952919-1962328
S_Shore


cg21029612
chr15: 89921258
LOC254559.TSS200
R
chr15: 89920793-89922768
Island


cg21552242
chr3: 157814326
SHOX2.UTR3
R
chr3: 157815581-
N_Shore






157816095


cg21703606
chr12: 54427884
HOXC4.UTR5
R
chr12: 54427025-54428709
Island


cg21900589
chr8: 22866294
RHOBTB2.GENEBODY
F
chr8: 22864324-22864588
S_Shore


cg22791545
chr17: 1924319
RTN4RL1.GENEBODY
R
chr17: 1927051-1929408
N_Shelf


cg22821554
chr7: 99383155
CYP3A4.TSS1500
F


cg23055499
chr12: 51847363
SLC4A8.GENEBODY
F


cg23172995
chr5: 150486801
ANXA6.GENEBODY
R


cg23714707
chr17: 17418691
PEMT.GENEBODY
R


cg23833461
chr17: 9929528
GAS7.EXON1
R


cg24603972
chr10: 61434211
SLC16A9.GENEBODY
F


cg25129480
chr1: 185126704
C1orf25.TSS1500
F
chr1: 185125850-
Island






185126705


cg25312122
chr1: 160184732
PEA15.UTR3
R


cg25425390
chr12: 42763958
PPHLN1.GENEBODY
R


cg25985583
chr7: 26404716
SNX10.GENEBODY
R


cg26306056
chr6: 32972989
HLA-DOA.UTR3
R
chr6: 32975684-32975926
N_Shelf


cg26353877
chr1: 159557886
APCS.GENEBODY
R


cg26558420
chr20: 30331315
TPX2.UTR5
R
chr20: 30326913-30327430
S_Shelf


cg26577231
chr19: 18368873
KIAA1683.GENEBODY
F
chr19: 18368482-18368911
Island


cg26942930
chr7: 147804524
CNTNAP2.GENEBODY
R


cg27150178
chr19: 1456337
APC2.GENEBODY
F
chr19: 1456077-1456347
Island


cg01173794
chr19: 36131225
ETV2.TSS1500
F
chr19: 36134153-36135781
N_Shelf


cg24774182
chr15: 22017473
CXADRP2.TSS1500
F


cg27541374
chr17: 58042493
RNFT1.TSS1500
R
chr17: 58041846-58042463
S_Shore


cg00401265
chrX: 78003113
LPAR4.TSS200
F


cg00435063
chr7: 157454207
PTPRN2.GENEBODY
F
chr7: 157453774-
Island






157454208


cg00515756
chr11: 61464876
DAGLA.UTR5
R


cg00653387
chr7: 137028535
PTN.UTR5
F


cg00808053
chr12: 6125746
VWF.GENEBODY
F


cg00808511
chr16: 52495237
TOX3.GENEBODY
R


cg01132064
chr11: 46382562
DGKZ.GENEBODY
F


cg01403030
chr9: 19026479
FAM154A.GENEBODY
R
chr9: 19027850-19028064
N_Shore


cg01507200
chr1: 247877066
OR6F1.TSS1500
R


cg01708636
chr4: 166301085
CPE.GENEBODY
R
chr4: 166299975-
S_Shore






166300668


cg02077068
chr16: 19872240
GPRC5B.GENEBODY
R


cg03081691
chr1: 226188006
C1orf55.TSS1500
F
chr1: 226186803-
S_Shore






226187336


cg03306486
chr19: 1467952
APC2.GENEBODY
F
chr19: 1465206-1471241
Island


cg04383012
chr2: 231921692
PSMD1.EXON1
R
chr2: 231921413-
Island






231921972


cg04655481
chr9: 125796809
GPR21.TSS200
F


cg04665588
chr17: 14243776
HS3ST3B1.GENEBODY
F


cg04804648
chr17: 72348295
KIF19.GENEBODY
F
chr17: 72347924-72348322
Island


cg04809274
chr6: 32977254
HLA-DOA.EXON1
F
chr6: 32975684-32975926
S_Shore


cg04962134
chr11: 55653310
SPRYD5.GENEBODY
R


cg05221455
chr11: 829616
EFCAB4A.GENEBODY
F
chr11: 829284-833558
Island


cg05720937
chr2: 98280362
ACTR1B.EXON1
R
chr2: 98280063-98280871
Island


cg06517181
chr10: 134994252
KNDC1.GENEBODY
F
chr10: 134993121-
S_Shore






134993324


cg06572563
chr19: 1132966
SBNO2.GENEBODY
R


cg07100542
chr1: 17402079
PADI2.GENEBODY
R


cg07436694
chr16: 21638444
METTL9.GENEBODY
R


cg07586799
chr3: 195591722
TNK2.GENEBODY
R
chr3: 195594836-
N_Shelf






195595494


cg07870237
chr5: 131348431
ACSL6.TSS1500
F
chr5: 131346892-
S_Shore






131347776


cg08984900
chr17: 34430281
CCL4.TSS1500
R


cg09524686
chr11: 829182
EFCAB4A.GENEBODY
F
chr11: 829284-833558
N_Shore


cg09565226
chr16: 84759648
USP10.GENEBODY
R


cg10256976
chr11: 20078682
NAV2.GENEBODY
F


cg10327976
chr15: 42843303
HAUS2.GENEBODY
R
chr15: 42840462-42841116
S_Shelf


cg10341513
chr22: 51041242
MAPK8IP2.TSS1500
R
chr22: 51042293-51043422
N_Shore


cg10521450
chr10: 105439280
SH3PXD2A.GENEBODY
R


cg10959048
chr3: 93694020
PROS1.TSS1500
R
chr3: 93692554-93692783
S_Shore


cg11049863
chr17: 80832470
TBCD.GENEBODY
F
chr17: 80829533-80829871
S_Shelf


cg11150074
chr1: 200863559
C1orf106.TSS1500
R
chr1: 200860076-
S_Shelf






200860576


cg11321144
chr4: 151178020
DCLK2.UTR3
F
chr4: 151177347-
S_Shore






151177559


cg11521965
chr7: 137028604
PTN.TSS200
F


cg11581706
chr7: 82072141
CACNA2D1.GENEBODY
F
chr7: 82072021-82073520
Island


cg12196847
chr14: 81426577
TSHR.GENEBODY
R


cg12617146
chr10: 97101836
SORBS1.GENEBODY
R


cg13617795
chr7: 105137683
PUS7.GENEBODY
F


cg13698125
chr9: 140391480
PNPLA7.GENEBODY
R
chr9: 140389453-
S_Shore






140389751


cg13921245
chr6: 33053791
HLA-DPB1.GENEBODY
F


cg14022090
chr11: 34642303
EHF.TSS1500
F


cg14147151
chr9: 138948000
NACC2.UTR5
R
chr9: 138941470-
S_Shelf






138944021


cg14322298
chr6: 10585683
GCNT2.GENEBODY
F


cg14402562
chr11: 8945810
C11orf16.GENEBODY
R


cg15287806
chr10: 237794
ZMYND11.GENEBODY
R


cg15332132
chr20: 62183964
C20orf195.TSS1500
R
chr20: 62185073-62185572
N_Shore


cg15367000
chr2: 239017149
ESPNL.GENEBODY
F


cg15463309
chr8: 141598157
EIF2C2.GENEBODY
F


cg16182685
chr2: 3260980
TSSC1.GENEBODY
F


cg16280667
chr11: 118754593
CXCR5.UTR5
F


cg16477417
chr17: 73342168
GRB2.GENEBODY
F


cg16711332
chr1: 6531727
PLEKHG5.GENEBODY
F
chr1: 6530536-6531814
Island


cg16791781
chr11: 986922
AP2A2.GENEBODY
R


cg17777731
chr6: 32976131
HLA-DOA.GENEBODY
R
chr6: 32975684-32975926
S_Shore


cg17947172
chr1: 204966197
NFASC.GENEBODY
R


cg18702239
chrX: 69663606
DLG3.TSS1500
F
chrX: 69665102-69665355
N_Shore


cg18715243
chr8: 37658755
GPR124.GENEBODY
R
chr8: 37654048-37656100
S_Shelf


cg18969798
chr4: 151157003
DCLK2.GENEBODY
R


cg19185706
chr10: 88475771
LDB3.GENEBODY
F
chr10: 88470905-88471934
S_Shelf


cg19409156
chr15: 48413040
SLC24A5.TSS200
R


cg19427746
chr17: 4889932
CAMTA2.UTR5
R
chr17: 4890282-4890991
N_Shore


cg20100408
chr6: 33050888
HLA-DPB1.GENEBODY
F
chr6: 33048416-33048814
S_Shelf


cg20541233
chr21: 18938039
CXADR.UTR3
R


cg20907136
chr6: 33041221
HLA-DPA1.GENEBODY
F


cg20938170
chr11: 75428910
MOGAT2.TSS200
R


cg21748244
chr5: 169713179
LCP2.GENEBODY
F


cg21776674
chr1: 6160143
KCNAB2.UTR3
F


cg22007216
chr4: 155312410
DCHS2.GENEBODY
R


cg22381352
chr1: 146742008
CHD1L.GENEBODY
R


cg22442557
chr17: 79011352
BAIAP2.GENEBODY
R
chr17: 79008929-79009762
S_Shore


cg22858170
chr5: 39204386
FYB.UTR5
R


cg23095615
chr6: 146136563
FBXO30.TSS1500
F
chr6: 146136325-
Island






146136564


cg23326197
chr7: 99382370
CYP3A4.TSS1500
F


cg23645261
chr19: 30940563
ZNF536.GENEBODY
F
chr19: 30941853-30942181
N_Shore


cg23676767
chr1: 226918736
ITPKB.GENEBODY
R


cg23699947
chr12: 27167077
TM7SF3.EXON1
F
chr12: 27166996-27167464
Island


cg23777946
chr18: 24125409
KCTD1.UTR5
R
chr18: 24126780-24131138
N_Shore


cg23998119
chr14: 77600217
ZDHHC22.GENEBODY
R


cg24214000
chr22: 50282386
ZBED4.UTR3
F
chr22: 50279568-50280376
S_Shelf


cg24396358
chr6: 32977400
HLA-DOA.TSS200
F
chr6: 32975684-32975926
S_Shore


cg24436022
chr22: 45691661
UPK3A.UTR3
F


cg24625894
chr8: 145638202
SLC39A4.GENEBODY
R
chr8: 145637965-
Island






145639182


cg24678581
chr5: 170882542
FGF18.GENEBODY
R
chr5: 170883600-
N_Shore






170883836


cg24938100
chr6: 33091407
HLA-DPB2.GENEBODY
R


cg25693265
chr7: 6517860
KDELR2.GENEBODY
R


cg26345142
chr12: 109305794
SVOP.UTR3
F


cg26490671
chr7: 157670732
PTPRN2.GENEBODY
R
chr7: 157669879-
S_Shore






157670095


cg26692016
chr12: 7817844
APOBEC1.GENEBODY
R


cg26871279
chr11: 2423559
TSSC4.UTR5
R
chr11: 2421040-2422474
S_Shore


cg27504782
chr7: 94284258
SGCE.GENEBODY
R
chr7: 94284858-94286527
N_Shore


cg00731886
chr4: 1363008
KIAA1530.GENEBODY
F
chr4: 1364146-1364349
N_Shore


cg00896220
chr17: 34639327
CCL4L1.TSS1500
R


cg01443488
chr1: 159557514
APCS.TSS200
F


cg01924561
chr1: 43416103
SLC2A1.GENEBODY
F


cg04810997
chr7: 143140674
TAS2R60.EXON1
R


cg05677694
chr6: 33052797
HLA-DPB1.GENEBODY
F
chr6: 33048416-33048814
S_Shelf


cg11070176
chr11: 70489806
SHANK2.GENEBODY
F


cg11941526
chrX: 38660299
MID1IP1.TSS1500
F
chrX: 38662906-38664764
N_Shelf


cg14517144
chr10: 70098420
HNRNPH3.GENEBODY
F


cg14684709
chr13: 100547249
CLYBL.UTR3
F
chr13: 100547172-
Island






100547431


cg16537306
chr17: 9850268
GAS7.GENEBODY
R


cg17753661
chr1: 26441637
PDIK1L.GENEBODY
F
chr1: 26437319-26438917
S_Shelf


cg23710594
chr1: 33841330
PHC2.TSS200
R


cg00935894
chr8: 110705093
GOLSYN.TSS1500
R
chr8: 110703409-
S_Shore






110703897


cg01083652
chr15: 71629208
THSD4.GENEBODY
R


cg02075590
chr4: 125607552
ANKRD50.UTR5
R


cg02169973
chr19: 50983986
C19orf63.GENEBODY
F
chr19: 50983853-50984075
Island


cg02220617
chr14: 102312533
PPP2R5C.GENEBODY
R


cg02555215
chr12: 113497560
DTX1.GENEBODY
R
chr12: 113494389-
S_Shelf






113495534


cg02963493
chr19: 11568915
ELAVL3.GENEBODY
R
chr19: 11565384-11565711
S_Shelf


cg03252568
chr17: 41727259
MEOX1.GENEBODY
F
chr17: 41723219-41723826
S_Shelf
















TABLE 5







Top 1000 methylation sites associated with the SCLC-N subtype












Methylation Site
Position (GRCh 37)
Gene
Strand
CpG Island Name
Relation to CpG Island





cg23317857
chr6: 41696297
TFEB.UTR5
F




cg16860004
chr8: 103137229
NCALD.TSS1500
F
chr8: 103135914-103136775
S_Shore


cg20149780
chr1: 15751063
EFHD2.GENEBODY
F


cg00448761
chr19: 6066102
RFX2.UTR5
R


cg01942646
chr1: 27240694
NROB2.TSS200
R


cg19343518
chr6: 157508679
ARID1B.GENEBODY
F


cg03332546
chr19: 16553887
EPS15L1.GENEBODY
F


cg16177693
chr1: 27240669
NR0B2.TSS200
R


cg23861617
chr4: 83422170
TMEM150C.GENEBODY
F


cg21147709
chr1: 12004662
PLOD1.GENEBODY
R


cg26713273
chr12: 11906243
ETV6.GENEBODY
R


cg01570265
chr14: 70180751
KIAA0247.UTR3
R


cg02573468
chr15: 41224537
DLL4.GENEBODY
F
chr15: 41217789-41223180
S_Shore


cg19280540
chr19: 16553711
EPS15L1.GENEBODY
R


cg05552035
chr8: 37699239
GPR124.GENEBODY
F
chr8: 37698846-37699931
Island


cg22016731
chr1: 40311142
TRIT1.GENEBODY
F


cg15578140
chr7: 147718109
MIR548F3.GENEBODY
R


cg03561416
chr6: 157254584
ARID1B.GENEBODY
F


cg08482167
chr6: 144066847
PHACTR2.GENEBODY
R


cg25167574
chr4: 79861398
PAQR3.TSS1500
F
chr4: 79860213-79860745
S_Shore


cg23430388
chr3: 63429828
SYNPR.GENEBODY
F


cg21881338
chr12: 125566189
AACS.GENEBODY
F
chr12: 125569828-125570140
N_Shelf


cg24500959
chr10: 99474813
MARVELD1.GENEBODY
R
chr10: 99473084-99473291
S_Shore


cg07099407
chr6: 43027930
KLC4.TSS1500
R
chr6: 43026939-43027841
S_Shore


cg13464573
chr2: 7172097
RNF144A.GENEBODY
F
chr2: 7172296-7172512
N_Shore


cg21436938
chr9: 116061416
RNF183.TSS200
F


cg10173620
chr15: 89658904
ABHD2.UTR5
R


cg09337391
chr20: 45871363
ZMYND8.GENEBODY
R
chr20: 45867654-45868111
S_Shelf


cg19307500
chr19: 1083193
HMHA1.GENEBODY
R
chr19: 1082576-1083430
Island


cg14651919
chr17: 74075189
ZACN.TSS200
R
chr17: 74070404-74073530
S_Shore


cg04645676
chr5: 10655569
ANKRD33B.UTR3
F


cg20731121
chr3: 111636305
PHLDB2.GENEBODY
F


cg25727520
chr2: 37576821
QPCT.GENEBODY
R


cg26003056
chr5: 89908195
GPR98.GENEBODY
F


cg00072720
chr17: 7165831
CLDN7.TSS200
R
chr17: 7164285-7166245
Island


cg05564438
chr11: 64120286
CCDC88B.GENEBODY
R


cg21763058
chr12: 49740976
DNAJC22.TSS200
R
chr12: 49738680-49740841
S_Shore


cg00325866
chr15: 62359130
C2CD4A.TSS200
F
chr15: 62359827-62360995
N_Shore


cg04868764
chr15: 41137019
SPINT1.GENEBODY
F
chr15: 41135719-41137210
Island


cg16609181
chr19: 1083007
HMHA1.GENEBODY
R
chr19: 1082576-1083430
Island


cg05767421
chr8: 120221185
MAL2.GENEBODY
R
chr8: 120220388-120221222
Island


cg12379775
chr20: 62669791
NCRNA00176.GENEBODY
F
chr20: 62669304-62670730
Island


cg26215113
chr2: 234369962
DGKD.GENEBODY
R
chr2: 234369786-234370099
Island


cg02707152
chr11: 64980819
SLC22A20.TSS1500
R


cg25718402
chr17: 7165909
CLDN7.TSS200
F
chr17: 7164285-7166245
Island


cg11944076
chr15: 51997390
SCG3.GENEBODY
R


cg17519949
chr19: 15292440
NOTCH3.GENEBODY
R
chr19: 15292399-15292632
Island


cg18777231
chr20: 62669807
NCRNA00176.GENEBODY
F
chr20: 62669304-62670730
Island


cg27269561
chr16: 3072713
HCFC1R1.UTR3
F
chr16: 3073686-3074443
N_Shore


cg13275679
chr17: 73151149
HN1.TSS1500
R
chr17: 73149830-73150885
S_Shore


cg11785537
chr12: 6484729
SCNN1A.GENEBODY
F


cg27430662
chr1: 109656708
KIAA1324.UTR5
R
chr1: 109656095-109656611
S_Shore


cg01804664
chr5: 149669414
CAMK2A.TSS200
F


cg22514229
chr1: 94118054
BCAR3.GENEBODY
R


cg09915444
chr15: 62359275
C2CD4A.EXON1
F
chr15: 62359827-62360995
N_Shore


cg20143111
chr4: 10673188
CLNK.UTR5
R


cg12609243
chr3: 54155240
CACNA2D3.TSS1500
R
chr3: 54155239-54157025
Island


cg25191573
chr3: 49037070
P4HTM.GENEBODY
R


cg02910913
chr17: 72968277
C17orf28.GENEBODY
R
chr17: 72968167-72969164
Island


cg21275690
chr16: 3072970
HCFC1R1.GENEBODY
F
chr16: 3073686-3074443
N_Shore


cg03893692
chr5: 149669484
CAMK2A.TSS200
F


cg11744304
chr7: 100875822
CLDN15.GENEBODY
R
chr7: 100875555-100876212
Island


cg21486510
chr2: 7171998
RNF144A.GENEBODY
F
chr2: 7172296-7172512
N_Shore


cg21761356
chr12: 97892013
RMST.GENEBODY
F


cg17553353
chr3: 111718565
TAGLN3.GENEBODY
R


cg02703870
chr16: 82045140
SDR42E1.TSS200
R
chr16: 82044886-82045306
Island


cg02641676
chr8: 42397764
C8orf40.UTR5
R
chr8: 42396235-42397195
S_Shore


cg06829681
chr11: 12867453
TEAD1.GENEBODY
F


cg09565670
chr19: 39368408
RINL.UTR5
R


cg15873327
chr19: 8398677
KANK3.GENEBODY
F
chr19: 8397958-8400461
Island


cg25960403
chr4: 11370015
MIR572.TSS1500
F
chr4: 11370229-11370886
N_Shore


cg01643250
chr19: 15292485
NOTCH3.GENEBODY
R
chr19: 15292399-15292632
Island


cg11445764
chr5: 147773164
FBXO38.UTR5
R


cg20147326
chr11: 33913538
LMO2.EXON1
R


cg24994355
chr10: 99445520
AVPI1.UTR5
F
chr10: 99446696-99447400
N_Shore


cg10965131
chr7: 151078995
WDR86.GENEBODY
R
chr7: 151078462-151079536
Island


cg17522866
chr5: 147052374
JAKMIP2.UTR5
F


cg25147139
chr12: 49740718
DNAJC22.TSS1500
R
chr12: 49738680-49740841
Island


cg26317549
chr15: 48497296
SLC12A1.TSS1500
R


cg02737268
chr20: 3780182
CDC25B.GENEBODY
F
chr20: 3776198-3776419
S_Shelf


cg26808293
chr16: 3072207
TNFRSF12A.UTR3
R
chr16: 3073686-3074443
N_Shore


cg15298719
chr17: 7165255
CLDN7.EXON1
R
chr17: 7164285-7166245
Island


cg01609559
chr6: 46138957
ENPP5.TSS1500
R


cg21445398
chr2: 125425654
CNTNAP5.GENEBODY
F


cg02659920
chr11: 726335
EPS8L2.GENEBODY
F
chr11: 725596-726870
Island


cg03852018
chr2: 149634410
KIF5C.GENEBODY
F
chr2: 149632682-149633882
S_Shore


cg04801402
chr6: 46138912
ENPP5.TSS200
F


cg08472795
chr2: 129067253
HS6ST1.GENEBODY
F


cg08918013
chr19: 55953951
SHISA7.EXON1
R
chr19: 55953371-55954641
Island


cg25693302
chr18: 55862678
NEDD4L.UTR5
R
chr18: 55862653-55862873
Island


cg07701837
chr2: 210516795
MAP2.UTR5
F


cg16371032
chr8: 95654541
ESRP1.GENEBODY
F
chr8: 95653898-95654733
Island


cg10207240
chr12: 122356781
WDR66.UTR5
R
chr12: 122356315-122356853
Island


cg02017200
chr19: 49256361
FUT1.UTR5
F
chr19: 49255778-49256495
Island


cg03477240
chr6: 20583779
CDKAL1.GENEBODY
F


cg04687437
chr19: 511113
C19orf20.GENEBODY
F
chr19: 506526-507133
S_Shelf


cg09195271
chr1: 20142497
RNF186.TSS1500
R


cg10515731
chr2: 220378996
ACCN4.UTR5
F
chr2: 220377743-220377946
S_Shore


cg22776856
chr16: 3072572
THOC6.TSS1500
R
chr16: 3073686-3074443
N_Shore


cg25846061
chr2: 236415673
AGAP1.GENEBODY
R


cg01226742
chr8: 37699923
GPR124.UTR3
F
chr8: 37698846-37699931
Island


cg04304450
chr22: 43525431
BIK.UTR3
F


cg04355435
chr1: 43736290
TMEM125.UTR5
F
chr1: 43738484-43738829
N_Shelf


cg08374799
chr12: 53601050
ITGB7.TSS200
R


cg10483275
chr5: 149669368
CAMK2A.UTR5
F


cg06961289
chr1: 156722410
HDGF.TSS200
F
chr1: 156720747-156722069
S_Shore


cg09726982
chr2: 220379016
ACCN4.UTR5
F
chr2: 220377743-220377946
S_Shore


cg17204557
chr2: 121223909
LOC84931.GENEBODY
R


cg19778003
chr3: 111718062
TAGLN3.EXON1
R


cg26064870
chr8: 102944342
NCALD.UTR5
R


cg13077545
chr17: 41832873
SOST.GENEBODY
R
chr17: 41832717-41833195
Island


cg26549084
chr3: 171759895
FNDC3B.UTR5
F
chr3: 171757493-171758724
S_Shore


cg27469783
chr19: 3801404
MATK.UTR5
F
chr19: 3801392-3801819
Island


cg03310469
chr2: 45236672
SIX2.TSS200
F
chr2: 45235511-45237792
Island


cg21151061
chr12: 50498016
GPD1.GENEBODY
R


cg14034852
chr17: 7165010
CLDN7.GENEBODY
F
chr17: 7164285-7166245
Island


cg17111837
chr20: 62669757
NCRNA00176.GENEBODY
R
chr20: 62669304-62670730
Island


cg20126106
chr3: 111718135
TAGLN3.EXON1
R


cg05304366
chr15: 40226905
EIF2AK4.GENEBODY
F
chr15: 40226210-40226631
S_Shore


cg21191365
chr14: 90529014
KCNK13.GENEBODY
F
chr14: 90526696-90528951
S_Shore


cg14186816
chr18: 55862763
NEDD4L.UTR5
F
chr18: 55862653-55862873
Island


cg18993457
chr11: 441983
ANO9.UTR5
R


cg08442823
chr11: 45951803
PHF21A.UTR3
F


cg13002109
chr3: 124041146
KALRN.GENEBODY
F


cg14914552
chr8: 97340188
PTDSS1.GENEBODY
R


cg18335326
chr6: 30653659
KIAA1949.GENEBODY
F
chr6: 30654392-30654934
N_Shore


cg04671541
chr3: 111717682
TAGLN3.EXON1
F


cg07251887
chr17: 73641809
LOC100130933.TSS1500
R


cg00010853
chr6: 30653167
KIAA1949.GENEBODY
F
chr6: 30654392-30654934
N_Shore


cg15245625
chr18: 55862676
NEDD4L.UTR5
R
chr18: 55862653-55862873
Island


cg24750887
chr4: 89534723
HERC3.GENEBODY
R


cg12473285
chr17: 41832975
SOST.GENEBODY
R
chr17: 41832717-41833195
Island


cg08196842
chr14: 65016517
C14orf50.TSS200
R
chr14: 65016516-65016909
Island


cg08841552
chr9: 140444378
PNPLA7.GENEBODY
F
chr9: 140445653-140446891
N_Shore


cg20465143
chr8: 144653962
C8orf73.GENEBODY
F
chr8: 144653774-144653976
Island


cg21563471
chr2: 158184535
ERMN.TSS1500
R


cg14770958
chr3: 111717793
TAGLN3.EXON1
R


cg26068911
chr5: 89967277
GPR98.GENEBODY
F


cg27281690
chr2: 7171963
RNF144A.GENEBODY
F
chr2: 7172296-7172512
N_Shore


cg10828127
chr21: 41550814
DSCAM.GENEBODY
R
chr21: 41554618-41554959
N_Shelf


cg15554875
chr2: 45236686
SIX2.TSS200
F
chr2: 45235511-45237792
Island


cg05081953
chr2: 158184543
ERMN.TSS1500
F


cg09717545
chr19: 917707
KISS1R.EXON1
R
chr19: 917034-920787
Island


cg11104313
chr3: 111717534
TAGLN3.TSS200
F


cg11672757
chr2: 241080172
OTOS.TSS200
R


cg15169077
chr6: 46139019
ENPP5.TSS1500
F


cg04245402
chr19: 751241
C19orf21.UTR5
R


cg08200404
chr15: 62359539
C2CD4A.UTR5
F
chr15: 62359827-62360995
N_Shore


cg10245608
chr9: 92221282
GADD45G.UTR3
R
chr9: 92219771-92221411
Island


cg21068094
chr18: 55862711
NEDD4L.UTR5
R
chr18: 55862653-55862873
Island


cg04994773
chr1: 109656777
KIAA1324.UTR5
R
chr1: 109656095-109656611
S_Shore


cg10976861
chr2: 239149937
HES6.TSS1500
F
chr2: 239147592-239149900
S_Shore


cg16638385
chr17: 41832753
SOST.GENEBODY
R
chr17: 41832717-41833195
Island


cg22618164
chr12: 122356400
WDR66.TSS200
F
chr12: 122356315-122356853
Island


cg07028869
chr12: 49741164
DNAJC22.UTR5
R
chr12: 49738680-49740841
S_Shore


cg07354371
chr1: 43736391
TMEM125.UTR5
R
chr1: 43738484-43738829
N_Shelf


cg07637741
chr6: 159084426
SYTL3.GENEBODY
F


cg04886060
chr16: 82044788
SDR42E1.UTR5
F
chr16: 82044886-82045306
N_Shore


cg16931969
chr4: 113985495
ANK2.GENEBODY
F


cg24652919
chr16: 3073191
HCFC1R1.GENEBODY
R
chr16: 3073686-3074443
N_Shore


cg06537333
chr16: 85643863
KIAA0182.TSS1500
F
chr16: 85644089-85644323
N_Shore


cg14052044
chr19: 751159
C19orf21.EXON1
R
chr19: 746300-747161
S_Shelf


cg18070562
chr17: 8013617
ALOXE3.GENEBODY
R
chr17: 8013172-8013657
Island


cg25736482
chr19: 54677232
MBOAT7.UTR3
R


cg27417294
chr10: 81904244
PLAC9.GENEBODY
R


cg27536453
chr3: 169530417
LRRC34.TSS200
F
chr3: 169529875-169530435
Island


cg03646740
chr13: 114813015
RASA3.GENEBODY
R
chr13: 114813942-114814457
N_Shore


cg11482099
chr11: 31833477
PAX6.TSS1500
F
chr11: 31831620-31839038
Island


cg18998911
chr3: 111718245
TAGLN3.EXON1
R


cg17749454
chr17: 73101934
SLC16A5.GENEBODY
R
chr17: 73105229-73106667
N_Shelf


cg02449373
chr19: 49256123
FUT1.UTR5
F
chr19: 49255778-49256495
Island


cg03751944
chr19: 1081936
HMHA1.GENEBODY
F
chr19: 1079682-1081937
Island


cg05251389
chr22: 43525330
BIK.UTR3
F


cg15559684
chr3: 63428234
SYNPR.GENEBODY
R


cg27274706
chr11: 129685751
TMEM45B.EXON1
R
chr11: 129685737-129686211
Island


cg04930469
chr17: 41832882
SOST.GENEBODY
R
chr17: 41832717-41833195
Island


cg06839900
chr1: 2461900
HES5.TSS1500
R
chr1: 2460760-2462010
Island


cg03018001
chr19: 751098
C19orf21.TSS200
R
chr19: 746300-747161
S_Shelf


cg08253704
chr6: 30653242
KIAA1949.GENEBODY
R
chr6: 30654392-30654934
N_Shore


cg15925940
chr14: 105330630
KIAA0284.TSS1500
R
chr14: 105330514-105332186
Island


cg18612589
chr17: 7165847
CLDN7.TSS200
R
chr17: 7164285-7166245
Island


cg13401831
chr22: 18593307
TUBA8.TSS1500
R
chr22: 18593113-18594197
Island


cg20234170
chr11: 34460107
CAT.TSS1500
F
chr11: 34460165-34460857
N_Shore


cg22481263
chr1: 906493
PLEKHN1.GENEBODY
R
chr1: 906296-906538
Island


cg03021329
chr3: 124554058
ITGB5.GENEBODY
F


cg07720856
chr2: 232572668
PTMA.TSS1500
F
chr2: 232571137-232575833
Island


cg15602548
chr2: 54786148
SPTBN1.GENEBODY
F
chr2: 54785026-54785969
S_Shore


cg20925462
chr3: 111717806
TAGLN3.TSS200
R


cg00510447
chr16: 3071608
TNFRSF12A.GENEBODY
F
chr16: 3070095-3071305
S_Shore


cg07460919
chr3: 183980626
ECE2.GENEBODY
R
chr3: 183977548-183980633
Island


cg14194715
chr13: 32651552
FRY.GENEBODY
F


cg05962028
chr12: 214000
IQSEC3.GENEBODY
F
chr12: 213763-214227
Island


cg14245347
chr6: 29856426
HLA-H.GENEBODY
R
chr6: 29855295-29856565
Island


cg17889402
chr18: 55862872
NEDD4L.UTR5
F
chr18: 55862653-55862873
Island


cg21521758
chr7: 150036287
RARRES2.GENEBODY
F
chr7: 150037459-150039031
N_Shore


cg00282244
chr7: 100876136
CLDN15.GENEBODY
F
chr7: 100875555-100876212
Island


cg01062519
chr17: 34122169
MMP28.GENEBODY
F
chr17: 34122024-34122801
Island


cg13302994
chr2: 210714233
UNC80.GENEBODY
F


cg16341266
chr7: 147256367
MIR548I4.TSS1500
F


cg17265693
chr17: 7166490
CLDN7.TSS1500
F
chr17: 7164285-7166245
S_Shore


cg17956387
chr1: 208418015
PLXNA2.TSS1500
R
chr1: 208416489-208418016
Island


cg12930882
chr5: 37825585
GDNF.GENEBODY
R


cg26335620
chr19: 48215149
EHD2.TSS1500
F
chr19: 48216486-48216837
N_Shore


cg11356571
chr19: 48219924
EHD2.GENEBODY
R
chr19: 48219831-48220298
Island


cg03469805
chr14: 105330648
KIAA0284.TSS1500
F
chr14: 105330514-105332186
Island


cg04608356
chr1: 27668433
SYTL1.TSS200
R


cg06644669
chr6: 30653799
KIAA1949.UTR5
R
chr6: 30654392-30654934
N_Shore


cg09865760
chr12: 49739893
DNAJC22.TSS1500
R
chr12: 49738680-49740841
Island


cg02512352
chr7: 151137048
CRYGN.EXON1
F
chr7: 151136933-151137273
Island


cg05098417
chr11: 64067858
C11orf20.TSS200
F
chr11: 64066757-64068741
Island


cg06740893
chr1: 12251869
TNFRSF1B.GENEBODY
R
chr1: 12251777-12251985
Island


cg12934258
chr6: 159084599
SYTL3.GENEBODY
F


cg21604615
chr1: 27668610
SYTL1.EXON1
F


cg01562385
chr19: 10698098
AP1M2.TSS200
R
chr19: 10697786-10698099
Island


cg17420360
chr12: 49740840
DNAJC22.TSS200
F
chr12: 49738680-49740841
Island


cg26020521
chr11: 8680436
TRIM66.TSS200
F


cg26877508
chr15: 71495324
THSD4.GENEBODY
R


cg05305327
chr20: 32156436
CBFA2T2.GENEBODY
R


cg03738134
chr8: 144653855
C8orf73.GENEBODY
R
chr8: 144653774-144653976
Island


cg17236870
chr4: 94122883
GRID2.GENEBODY
F


cg08439728
chr6: 31097073
PSORS1C1.UTR5
F


cg01930441
chr16: 21289268
CRYM.GENEBODY
F
chr16: 21289419-21289819
N_Shore


cg05639747
chr12: 49740942
DNAJC22.TSS200
R
chr12: 49738680-49740841
S_Shore


cg25989783
chr8: 102699486
NCALD.UTR3
F


cg01864032
chrX: 69674332
DLG3.GENEBODY
F
chrX: 69674799-69675305
N_Shore


cg12503394
chr7: 1596118
TMEM184A.TSS200
R


cg16884042
chr2: 223289683
SGPP2.GENEBODY
F
chr2: 223288922-223290013
Island


cg26785346
chr4: 186732936
SORBS2.UTR5
R


cg01708552
chr7: 100815485
C7orf52.GENEBODY
R
chr7: 100815484-100816995
Island


cg02487823
chr3: 197440451
KIAA0226.GENEBODY
F


cg13036352
chr6: 30651825
KIAA1949.GENEBODY
F
chr6: 30654392-30654934
N_Shelf


cg13478289
chr6: 33132650
COL11A2.GENEBODY
F
chr6: 33129291-33129718
S_Shelf


cg18010718
chr17: 74075195
ZACN.TSS200
R
chr17: 74070404-74073530
S_Shore


cg19095827
chr3: 107243066
BBX.UTR5
F
chr3: 107241845-107242731
S_Shore


cg23350812
chr2: 236415734
AGAP1.GENEBODY
R


cg01033299
chr12: 53601015
ITGB7.TSS200
R


cg02492946
chr1: 21667630
ECE1.GENEBODY
R
chr1: 21671360-21672319
N_Shelf


cg26575738
chr17: 44896168
WNT3.TSS200
F
chr17: 44895800-44897025
Island


cg00715124
chr6: 3227026
TUBB2B.GENEBODY
R
chr6: 3227025-3229688
Island


cg03182958
chr2: 223288923
SGPP2.TSS1500
R
chr2: 223288922-223290013
Island


cg05650846
chr16: 3078142
CCDC64B.GENEBODY
R
chr16: 3078141-3078553
Island


cg10544251
chr1: 156215727
PAQR6.UTR5
R
chr1: 156215368-156215899
Island


cg03230858
chr19: 751124
C19orf21.TSS200
R
chr19: 746300-747161
S_Shelf


cg03880611
chr5: 31889373
PDZD2.GENEBODY
F


cg21094405
chr13: 113656117
MCF2L.GENEBODY
R
chr13: 113656116-113656379
Island


cg22807241
chr7: 147709862
MIR548F3.GENEBODY
R


cg24837219
chr3: 132772692
TMEM108.UTR5
R


cg01100330
chr22: 39639518
PDGFB.GENEBODY
R
chr22: 39638219-39640966
Island


cg19477361
chr19: 2607903
GNG7.UTR5
R
chr19: 2607725-2607967
Island


cg22453183
chr5: 89940953
GPR98.GENEBODY
F


cg09701233
chr2: 236415814
AGAP1.GENEBODY
R


cg18814808
chr5: 143698198
KCTD16.GENEBODY
R


cg19529471
chr13: 35517634
NBEA.GENEBODY
R


cg15766101
chr19: 46519228
CCDC61.GENEBODY
R
chr19: 46518283-46520080
Island


cg17499826
chr19: 46284986
DMPK.GENEBODY
F
chr19: 46282544-46283127
S_Shore


cg22540067
chr2: 125305001
CNTNAP5.GENEBODY
F


cg02445972
chr17: 7166593
CLDN7.TSS1500
R
chr17: 7164285-7166245
S_Shore


cg23098020
chr1: 153651886
NPR1.EXON1
F
chr1: 153650830-153652375
Island


cg24302354
chr19: 48219029
EHD2.UTR5
R
chr19: 48219831-48220298
N_Shore


cg19469357
chr7: 8474830
NXPH1.UTR5
R
chr7: 8473139-8475199
Island


cg00144550
chr2: 100937796
LONRF2.GENEBODY
R
chr2: 100937779-100939059
Island


cg11303127
chr12: 49740807
DNAJC22.TSS1500
F
chr12: 49738680-49740841
Island


cg27320207
chr19: 15307057
NOTCH3.GENEBODY
R
chr19: 15306243-15307111
Island


cg03042971
chr17: 47301348
PHOSPHO1.UTR3
R
chr17: 47301545-47302477
N_Shore


cg05020685
chr4: 40858965
APBB2.GENEBODY
F
chr4: 40858884-40859162
Island


cg07035875
chr16: 52557205
TOX3.UTR5
R


cg12105190
chr6: 30653407
KIAA1949.GENEBODY
R
chr6: 30654392-30654934
N_Shore


cg18079653
chr10: 72648646
PCBD1.TSS200
R
chr10: 72647738-72648317
S_Shore


cg01200905
chr16: 52480264
TOX3.GENEBODY
R


cg07543967
chr19: 49055443
SULT2B1.EXON1
R


cg08389577
chr6: 3229379
TUBB2B.TSS1500
R
chr6: 3227025-3229688
Island


cg13796218
chr1: 11750663
MAD2L2.UTR5
R
chr1: 11750701-11752651
N_Shore


cg15927865
chr10: 104159579
NFKB2.GENEBODY
F
chr10: 104159096-104159536
S_Shore


cg17677988
chr4: 10687769
CLNK.TSS1500
F


cg02333237
chr14: 50802971
CDKL1.GENEBODY
R


cg05467716
chr17: 62774079
LOC146880.GENEBODY
F
chr17: 62774366-62777797
N_Shore


cg00452755
chr1: 28864993
SNHG3-RCC1.GENEBODY
R


cg14423168
chr8: 41400312
GINS4.UTR3
R


cg14373410
chr14: 81426234
TSHR.GENEBODY
R


cg01033600
chr19: 7964703
LRRC8E.GENEBODY
F
chr19: 7964439-7964704
Island


cg16616765
chr2: 197456534
HECW2.UTR5
R
chr2: 197457392-197458522
N_Shore


cg08093568
chr7: 27626595
HIBADH.GENEBODY
F


cg05152503
chr20: 30407098
MYLK2.TSS200
R
chr20: 30410547-30410832
N_Shelf


cg22970357
chr2: 119600408
EN1.UTR3
R
chr2: 119599458-119600966
Island


cg00791283
chr12: 79498966
SYT1.UTR5
R


cg26181372
chr9: 104198262
ALDOB.TSS1500
R


cg22780475
chr19: 45281526
CBLC.EXON1
F
chr19: 45281133-45281355
S_Shore


cg09336589
chr17: 7107939
DLG4.GENEBODY
F
chr17: 7108304-7108654
N_Shore


cg25976170
chr22: 29707585
GAS2L1.UTR3
F
chr22: 29707479-29707797
Island


cg07557423
chr4: 42657903
ATP8A1.GENEBODY
F
chr4: 42658278-42659550
N_Shore


cg07127888
chr8: 41400789
GINS4.UTR3
F


cg16293838
chr1: 6330521
ACOT7.GENEBODY
F


cg17397069
chr5: 156110742
SGCD.GENEBODY
R


cg15580167
chr2: 175629219
CHRNA1.TSS200
F


cg14414874
chr9: 126157693
DENND1A.GENEBODY
F
chr9: 126154226-126154562
S_Shelf


cg03167954
chr22: 29707782
GAS2L1.UTR3
R
chr22: 29707479-29707797
Island


cg22976732
chr22: 28191914
MN1.GENEBODY
F
chr22: 28192793-28198592
N_Shore


cg00927494
chr11: 69924230
ANO1.TSS200
R
chr11: 69924338-69925197
N_Shore


cg21661983
chr12: 72353490
TPH2.GENEBODY
F


cg00664609
chr16: 2198075
RAB26.TSS1500
R
chr16: 2198455-2199129
N_Shore


cg23924526
chr2: 45998548
PRKCE.GENEBODY
R


cg03180426
chr9: 139964156
C9orf140.GENEBODY
R
chr9: 139964155-139965284
Island


cg10153942
chr19: 54982500
CDC42EP5.UTR5
R
chr19: 54982388-54982897
Island


cg11282156
chr3: 63428840
SYNPR.UTR5
F


cg18003659
chr2: 175629267
CHRNA1.TSS200
R


cg01862650
chr5: 143619194
KCTD16.GENEBODY
R


cg01828813
chr6: 33132705
COL11A2.GENEBODY
R
chr6: 33129291-33129718
S_Shelf


cg19887293
chr6: 33132693
COL11A2.GENEBODY
R
chr6: 33129291-33129718
S_Shelf


cg25736198
chr12: 72345225
TPH2.GENEBODY
R


cg01159294
chr5: 143763289
KCTD16.GENEBODY
F


cg23009046
chr11: 119600595
PVRL1.TSS1500
R
chr11: 119598382-119600157
S_Shore


cg26548251
chr7: 147591462
MIR548F3.TSS1500
F


cg00177243
chr10: 18434068
CACNB2.GENEBODY
F
chr10: 18429125-18430234
S_Shelf


cg03050127
chr17: 59413660
BCAS3.GENEBODY
R


cg26357587
chr11: 120110882
POU2F3.TSS200
R
chr11: 120110497-120110719
S_Shore


cg02965092
chr12: 72347052
TPH2.GENEBODY
F


cg07961632
chr1: 27668421
SYTL1.TSS200
R


cg10380643
chr1: 1356764
LOC441869.TSS200
R
chr1: 1355159-1356000
S_Shore


cg17790159
chr6: 33133083
COL11A2.GENEBODY
R
chr6: 33129291-33129718
S_Shelf


cg14154859
chr1: 220702826
MARK1.GENEBODY
F
chr1: 220701507-220702348
S_Shore


cg10120778
chr7: 42018795
GLI3.GENEBODY
F


cg15700587
chr7: 147065665
MIR548I4.GENEBODY
R


cg00333034
chr3: 183948058
VWA5B2.TSS1500
F
chr3: 183947040-183948801
Island


cg00789347
chr16: 2039030
SYNGR3.TSS1500
F
chr16: 2040034-2040628
N_Shore


cg01507577
chr7: 146484609
CNTNAP2.GENEBODY
R


cg02379560
chr4: 40859280
APBB2.GENEBODY
F
chr4: 40858884-40859162
S_Shore


cg04917391
chr4: 40859259
APBB2.GENEBODY
F
chr4: 40858884-40859162
S_Shore


cg05894734
chr4: 40859249
APBB2.GENEBODY
F
chr4: 40858884-40859162
S_Shore


cg06485940
chr4: 40859293
APBB2.GENEBODY
F
chr4: 40858884-40859162
S_Shore


cg07035001
chr7: 146321053
CNTNAP2.GENEBODY
F


cg12455762
chr4: 40859095
APBB2.GENEBODY
F
chr4: 40858884-40859162
Island


cg14230238
chr19: 6066871
RFX2.UTR5
R


cg14248352
chr7: 146820536
CNTNAP2.GENEBODY
R


cg14652038
chr2: 222343519
EPHA4.GENEBODY
R


cg16364495
chr4: 40859251
APBB2.GENEBODY
F
chr4: 40858884-40859162
S_Shore


cg22519702
chr5: 147204189
SPINK1.UTR3
R


cg23735712
chr4: 40858984
APBB2.GENEBODY
F
chr4: 40858884-40859162
Island


cg23889772
chr19: 10077324
COL5A3.GENEBODY
F
chr19: 10077031-10077444
Island


cg25649655
chr8: 145692504
CYHR1.TSS1500
F
chr8: 145690605-145692505
Island


cg26244738
chr4: 40859344
APBB2.GENEBODY
R
chr4: 40858884-40859162
S_Shore


cg26470314
chr16: 2039411
SYNGR3.TSS1500
R
chr16: 2040034-2040628
N_Shore


cg01657995
chr6: 31804883
C6orf48.UTR5
F
chr6: 31802598-31802823
S_Shelf


cg02269097
chr12: 49487944
DHH.GENEBODY
R
chr12: 49487963-49488202
N_Shore


cg03392565
chr1: 212464932
PPP2R5A.GENEBODY
R


cg03957440
chr1: 214209324
PROX1.UTR3
R


cg09050775
chr12: 46762708
SLC38A2.GENEBODY
R
chr12: 46765134-46766633
N_Shelf


cg11526866
chr1: 20813614
CAMK2N1.TSS1500
F
chr1: 20810462-20813511
S_Shore


cg13109300
chr12: 49488587
DHH.UTR5
F
chr12: 49487963-49488202
S_Shore


cg16151451
chr11: 849153
TSPAN4.UTR5
F
chr11: 849087-850982
Island


cg16405211
chr7: 146897691
CNTNAP2.GENEBODY
R


cg17490790
chr19: 10125043
RDH8.GENEBODY
R
chr19: 10120750-10121231
S_Shelf


cg18804920
chr7: 146572638
CNTNAP2.GENEBODY
R


cg19075717
chr17: 48670940
CACNA1G.GENEBODY
R


cg24127874
chr2: 239149859
HES6.TSS1500
F
chr2: 239147592-239149900
Island


cg04303901
chr12: 97886312
RMST.GENEBODY
F


cg04695027
chr11: 65793986
CATSPER1.EXON1
R
chr11: 65789909-65790168
S_Shelf


cg04865716
chr19: 2290843
LINGO3.GENEBODY
R
chr19: 2289895-2291904
Island


cg05582979
chr4: 10686610
CLNK.TSS1500
F


cg06093379
chr17: 44896080
WNT3.UTR5
R
chr17: 44895800-44897025
Island


cg08384314
chr6: 30711680
IER3.UTR3
R
chr6: 30710307-30712440
Island


cg09267188
chr8: 97340225
PTDSS1.GENEBODY
R


cg12724192
chr4: 82392157
RASGEF1B.UTR5
R
chr4: 82392610-82393426
N_Shore


cg13067221
chr14: 23449582
JUB.GENEBODY
F
chr14: 23449886-23452174
N_Shore


cg16406078
chr20: 825634
FAM110A.GENEBODY
F
chr20: 825267-826276
Island


cg17971747
chr15: 45410236
DUOXA1.GENEBODY
F
chr15: 45408573-45409528
S_Shore


cg22942704
chr1: 20813574
CAMK2N1.TSS1500
R
chr1: 20810462-20813511
S_Shore


cg25151498
chr3: 185815992
ETV5.GENEBODY
F


cg25564319
chr3: 63558416
SYNPR.GENEBODY
F


cg27190967
chr16: 2039391
SYNGR3.TSS1500
F
chr16: 2040034-2040628
N_Shore


cg01920182
chr12: 23738340
SOX5.TSS1500
R


cg03595580
chr7: 97880848
TECPR1.UTR5
F
chr7: 97881132-97881906
N_Shore


cg04993130
chr11: 726759
EPS8L2.GENEBODY
R
chr11: 725596-726870
Island


cg06736134
chr5: 147040725
JAKMIP2.GENEBODY
R


cg09248054
chr1: 969257
AGRN.GENEBODY
F
chr1: 967966-970238
Island


cg11565786
chr5: 31944970
PDZD2.GENEBODY
R


cg16769791
chr8: 85178030
RALYL.UTR5
R


cg19741167
chr2: 86263270
POLR1A.GENEBODY
R


cg25225073
chr14: 90528983
KCNK13.GENEBODY
F
chr14: 90526696-90528951
S_Shore


cg26683639
chr6: 30653755
KIAA1949.GENEBODY
F
chr6: 30654392-30654934
N_Shore


cg07788437
chr19: 1799952
ATP8B3.GENEBODY
R
chr19: 1799934-1800248
Island


cg11207515
chr7: 146904205
CNTNAP2.GENEBODY
R


cg11540204
chr1: 60391699
CYP2J2.GENEBODY
R
chr1: 60392272-60392583
N_Shore


cg11799006
chr5: 147101975
JAKMIP2.UTR5
R


cg13369952
chr5: 147024959
JAKMIP2.GENEBODY
F


cg14074581
chr19: 36232218
TMEM149.UTR5
F
chr19: 36231186-36232219
Island


cg25183613
chr3: 111717557
TAGLN3.TSS200
F


cg00967013
chr13: 24735754
SPATA13.UTR5
F
chr13: 24734771-24735538
S_Shore


cg02120463
chr22: 39639003
PDGFB.GENEBODY
F
chr22: 39638219-39640966
Island


cg02578321
chr1: 247275872
C1orf229.TSS200
R
chr1: 247274585-247275757
S_Shore


cg03415518
chr12: 97885729
RMST.GENEBODY
R


cg04513006
chr16: 68270252
ESRP2.TSS200
F
chr16: 68269010-68272143
Island


cg05825085
chr16: 86379872
LOC732275.TSS1500
F


cg06185146
chr3: 63428305
SYNPR.GENEBODY
F


cg08669018
chr4: 82392280
RASGEF1B.UTR5
R
chr4: 82392610-82393426
N_Shore


cg09473576
chr1: 20813647
CAMK2N1.TSS1500
F
chr1: 20810462-20813511
S_Shore


cg10083593
chr11: 66049855
CNIH2.GENEBODY
R
chr11: 66049750-66050229
Island


cg11408784
chr17: 7166293
CLDN7.TSS1500
F
chr17: 7164285-7166245
S_Shore


cg11876912
chr3: 63602009
SYNPR.UTR3
F


cg13250388
chr22: 39641078
PDGFB.TSS200
R
chr22: 39638219-39640966
S_Shore


cg14615553
chr5: 147093466
JAKMIP2.UTR5
F


cg15149374
chr3: 19576826
KCNH8.UTR3
R


cg15225810
chr19: 750790
C19orf21.TSS1500
F
chr19: 746300-747161
S_Shelf


cg17075538
chr19: 15306892
NOTCH3.GENEBODY
R
chr19: 15306243-15307111
Island


cg17410295
chr12: 109729809
FOXN4.GENEBODY
F
chr12: 109729572-109729826
Island


cg17475643
chr8: 10261972
MSRA.GENEBODY
F
chr8: 10261900-10262222
Island


cg19464419
chr6: 94064439
EPHA7.GENEBODY
R


cg20391895
chr4: 10686394
CLNK.TSS200
F


cg24238564
chr11: 65779343
CST6.TSS200
F
chr11: 65779311-65779767
Island


cg26939195
chr6: 32077020
TNXB.UTR5
F


cg00026290
chr4: 10686554
CLNK.TSS200
F


cg02785561
chr8: 10262221
MSRA.GENEBODY
F
chr8: 10261900-10262222
Island


cg04221461
chr1: 243877024
AKT3.GENEBODY
R


cg05082805
chr7: 146489513
CNTNAP2.GENEBODY
F


cg09433131
chr8: 73480179
KCNB2.GENEBODY
F


cg11652360
chr6: 33160120
COL11A2.UTR5
R
chr6: 33159991-33160263
Island


cg19311889
chr12: 57483793
NAB2.GENEBODY
R
chr12: 57480797-57483116
S_Shore


cg00835193
chr19: 2291780
LINGO3.UTR5
R
chr19: 2289895-2291904
Island


cg01708411
chr12: 57631839
NDUFA4L2.UTR5
R
chr12: 57631932-57634578
N_Shore


cg02958126
chr11: 62370246
EML3.GENEBODY
F
chr11: 62368454-62370491
Island


cg02989255
chr6: 32063774
TNXB.GENEBODY
F
chr6: 32063533-32065044
Island


cg03525956
chr3: 174720287
NAALADL2.GENEBODY
F


cg06191495
chr2: 234264163
DGKD.GENEBODY
R


cg11809958
chr12: 32654929
FGD4.TSS200
R


cg11845241
chr7: 36960377
MIR1200.TSS1500
R


cg13179469
chr13: 107185675
EFNB2.GENEBODY
F
chr13: 107186468-107189024
N_Shore


cg18349863
chr6: 29912713
HLA-A.GENEBODY
F
chr6: 29910202-29911367
S_Shore


cg22138393
chr8: 97340270
PTDSS1.GENEBODY
F


cg26726230
chr17: 79225857
SLC38A10.GENEBODY
F


cg26961166
chr8: 73687160
KCNB2.GENEBODY
F


cg26999775
chr14: 105347803
KIAA0284.GENEBODY
R
chr14: 105350177-105350925
N_Shelf


cg00433917
chr19: 7915517
EVI5L.GENEBODY
F
chr19: 7913751-7913968
S_Shore


cg01422274
chr11: 849088
TSPAN4.UTR5
R
chr11: 849087-850982
Island


cg02245020
chr7: 143580147
FAM115A.UTR5
R
chr7: 143582125-143582610
N_Shore


cg04545963
chr14: 35872393
NFKBIA.GENEBODY
F
chr14: 35873047-35873990
N_Shore


cg07384913
chr3: 63637118
SNTN.TSS1500
F


cg07706352
chr19: 10077245
COL5A3.GENEBODY
R
chr19: 10077031-10077444
Island


cg08279008
chr2: 86263224
POLR1A.GENEBODY
F


cg10144863
chr8: 53235234
ST18.UTR5
R


cg11743827
chr3: 185080905
MAP3K13.TSS200
R


cg13720581
chr6: 32077017
TNXB.UTR5
F


cg15148573
chr7: 103498566
RELN.GENEBODY
F


cg16078836
chr3: 185081374
MAP3K13.UTR5
R


cg16226037
chr3: 175338261
NAALADL2.GENEBODY
R


cg16715129
chr11: 10477821
AMPD3.EXON1
F


cg19418951
chr3: 185080816
MAP3K13.TSS200
R


cg24519146
chr6: 33160318
COL11A2.TSS200
F
chr6: 33160945-33161337
N_Shore


cg25264265
chr3: 185080997
MAP3K13.EXON1
R


cg25479682
chr3: 185081403
MAP3K13.UTR5
R


cg26334804
chr19: 41724208
AXL.TSS1500
R


cg27287254
chr6: 33160067
COL11A2.UTR5
F
chr6: 33159991-33160263
Island


cg27633342
chr15: 52588279
MYO5C.TSS1500
R
chr15: 52587353-52588172
S_Shore


cg00037056
chr4: 956607
DGKQ.GENEBODY
F
chr4: 960505-960836
N_Shelf


cg01484141
chr17: 1624157
WDR81.GENEBODY
R
chr17: 1627745-1629897
N_Shelf


cg01679081
chr5: 60139131
ELOVL7.UTR5
F
chr5: 60139359-60140155
N_Shore


cg01886125
chr2: 110054030
SH3RF3.GENEBODY
F


cg03508107
chr17: 47654357
NXPH3.GENEBODY
F
chr17: 47653211-47654369
Island


cg03676636
chr4: 99064102
C4orf37.GENEBODY
R
chr4: 99064602-99064805
N_Shore


cg03850035
chr2: 222367110
EPHA4.GENEBODY
R


cg04083466
chr6: 25753732
SLC17A4.TSS1500
F


cg05396397
chr1: 11908164
NPPA.TSS1500
R


cg07107420
chr7: 8010894
GLCCI1.GENEBODY
F
chr7: 8008097-8009495
S_Shore


cg10242279
chr4: 10666415
CLNK.GENEBODY
R


cg12286569
chr19: 18722620
TMEM59L.TSS1500
R
chr19: 18722358-18724001
Island


cg13298116
chr11: 62369859
EML3.UTR3
R
chr11: 62368454-62370491
Island


cg14848284
chr2: 73143293
EMX1.TSS1500
R
chr2: 73143055-73148260
Island


cg16686429
chr19: 46284983
DMPK.GENEBODY
F
chr19: 46282544-46283127
S_Shore


cg18164281
chr20: 2797721
LOC100288797.UTR3
R
chr20: 2801639-2802135
N_Shelf


cg18776945
chr5: 147024842
JAKMIP2.GENEBODY
R


cg19250002
chr22: 20460068
RIMBP3.EXON1
F
chr22: 20459267-20461473
Island


cg19268434
chr6: 32076967
TNXB.UTR5
F


cg22076422
chr3: 63399168
SYNPR.GENEBODY
R


cg22168512
chr18: 74695224
MBP.GENEBODY
F
chr18: 74691262-74691466
S_Shelf


cg26248155
chr17: 7165849
CLDN7.TSS200
R
chr17: 7164285-7166245
Island


cg26574680
chr1: 235811860
GNG4.UTR5
F
chr1: 235811841-235814066
Island


cg26627129
chr19: 49552470
CGB8.TSS200
F


cg00102996
chr9: 92220617
GADD45G.GENEBODY
R
chr9: 92219771-92221411
Island


cg01589998
chr12: 109729478
FOXN4.GENEBODY
R
chr12: 109729572-109729826
N_Shore


cg01994275
chr7: 8480586
NXPH1.GENEBODY
F
chr7: 8481974-8482762
N_Shore


cg04013592
chr3: 63263076
SYNPR.TSS1500
F
chr3: 63263989-63264205
N_Shore


cg05848863
chr7: 16794078
TSPAN13.GENEBODY
R
chr7: 16793188-16794100
Island


cg09649438
chr10: 81904160
PLAC9.GENEBODY
R


cg13223402
chr2: 47797133
KCNK12.EXON1
R
chr2: 47796923-47799166
Island


cg13827782
chr9: 93377568
DIRAS2.UTR5
R


cg13978352
chr6: 30908706
DPCR1.TSS200
R


cg14750475
chr19: 50139654
RRAS.GENEBODY
F
chr19: 50143223-50143975
N_Shelf


cg15954675
chr3: 63542363
SYNPR.GENEBODY
R


cg19195419
chr19: 1799935
ATP8B3.GENEBODY
R
chr19: 1799934-1800248
Island


cg20083442
chr8: 73600575
KCNB2.GENEBODY
R


cg20353496
chr20: 825268
FAM110A.TSS200
R
chr20: 825267-826276
Island


cg21574349
chr3: 185080951
MAP3K13.TSS200
F


cg23422361
chr10: 135143617
CALY.UTR5
F
chr10: 135143373-135143580
S_Shore


cg23463608
chr19: 2607757
GNG7.UTR5
F
chr19: 2607725-2607967
Island


cg27233151
chr4: 82057467
PRKG2.GENEBODY
R


cg02365303
chr5: 147052498
JAKMIP2.UTR5
F


cg08694699
chr16: 68270282
ESRP2.TSS200
F
chr16: 68269010-68272143
Island


cg20668718
chr5: 146991927
JAKMIP2.GENEBODY
F


cg20818262
chr8: 73480145
KCNB2.GENEBODY
R


cg22459924
chr19: 2607850
GNG7.UTR5
F
chr19: 2607725-2607967
Island


cg11610754
chr19: 18722595
TMEM59L.TSS1500
R
chr19: 18722358-18724001
Island


cg12053155
chr13: 107186476
EFNB2.GENEBODY
R
chr13: 107186468-107189024
Island


cg12232903
chr4: 10686413
CLNK.TSS200
F


cg14995475
chr19: 6534774
TNFSF9.GENEBODY
R
chr19: 6534759-6535079
Island


cg16661000
chr15: 89437710
HAPLN3.UTR5
F
chr15: 89438176-89438850
N_Shore


cg17208427
chr16: 68679556
CDH3.GENEBODY
R
chr16: 68678686-68680149
Island


cg18721026
chr3: 183948313
VWA5B2.TSS200
F
chr3: 183947040-183948801
Island


cg00090619
chr6: 33160286
COL11A2.TSS200
F
chr6: 33160945-33161337
N_Shore


cg00106565
chr5: 146784171
DPYSL3.GENEBODY
F


cg00303541
chr3: 51741280
GRM2.UTR5
R
chr3: 51740740-51741413
Island


cg01177388
chr6: 32812704
PSMB8.UTR5
F
chr6: 32811494-32811839
S_Shore


cg01294327
chr19: 2291373
LINGO3.GENEBODY
R
chr19: 2289895-2291904
Island


cg02688752
chr5: 76115309
F2RL1.GENEBODY
R
chr5: 76115510-76116089
N_Shore


cg02969706
chr2: 6072283
LOC150622.TSS1500
R


cg03225210
chr7: 143579951
FAM115A.UTR5
R
chr7: 143582125-143582610
N_Shelf


cg04458159
chr6: 29856538
HLA-H.GENEBODY
F
chr6: 29855295-29856565
Island


cg04872123
chr6: 32049699
TNXB.GENEBODY
R
chr6: 32046815-32047094
S_Shelf


cg05057976
chr11: 65779667
CST6.EXON1
F
chr11: 65779311-65779767
Island


cg06321045
chr6: 31088343
CDSN.TSS200
F


cg06529264
chr13: 54887288
MIR1297.TSS1500
F


cg07435445
chr14: 103396379
AMN.GENEBODY
R
chr14: 103394397-103397070
Island


cg08551725
chr7: 30029776
SCRN1.TSS1500
F
chr7: 30028518-30029822
Island


cg11606261
chr12: 53775336
SP1.UTR5
R
chr12: 53774336-53774603
S_Shore


cg11794801
chr8: 10262020
MSRA.GENEBODY
R
chr8: 10261900-10262222
Island


cg11941546
chr17: 7165842
CLDN7.TSS200
R
chr17: 7164285-7166245
Island


cg13083674
chr19: 55953372
SHISA7.GENEBODY
R
chr19: 55953371-55954641
Island


cg13470920
chr19: 6772831
VAV1.EXON1
F


cg13723983
chr9: 132383362
C9orf50.TSS1500
F
chr9: 132382432-132383004
S_Shore


cg13851989
chr9: 14720244
CER1.GENEBODY
R


cg13984492
chr9: 104031694
LPPR1.GENEBODY
R


cg15705054
chr1: 154927709
PBXIP1.UTR5
R


cg17930034
chr14: 65016602
C14orf50.TSS200
R
chr14: 65016516-65016909
Island


cg20114890
chr6: 29856430
HLA-H.GENEBODY
R
chr6: 29855295-29856565
Island


cg21476000
chr12: 54430684
HOXC4.UTR5
F
chr12: 54427025-54428709
S_Shore


cg21552300
chr2: 175629224
CHRNA1.TSS200
F


cg23292266
chr19: 11285128
KANK2.GENEBODY
R
chr19: 11285122-11285332
Island


cg23517605
chr6: 3228365
TUBB2B.TSS1500
F
chr6: 3227025-3229688
Island


cg24735489
chr6: 31088352
CDSN.TSS200
F


cg25036095
chr4: 82392410
RASGEF1B.UTR5
F
chr4: 82392610-82393426
N_Shore


cg25580825
chr19: 10116808
COL5A3.GENEBODY
F
chr19: 10120750-10121231
N_Shelf


cg25661884
chr19: 10124267
RDH8.EXON1
R
chr19: 10120750-10121231
S_Shelf


cg25751198
chr12: 109729573
FOXN4.GENEBODY
R
chr12: 109729572-109729826
Island


cg00378510
chr19: 2291020
LINGO3.GENEBODY
F
chr19: 2289895-2291904
Island


cg17259886
chr5: 147040667
JAKMIP2.GENEBODY
F


cg00961418
chr11: 8616172
STK33.TSS1500
F
chr11: 8615397-8615889
S_Shore


cg01218350
chr2: 210517441
MAP2.UTR5
R


cg01974715
chr19: 41724129
AXL.TSS1500
F


cg02374996
chr9: 92220771
GADD45G.GENEBODY
F
chr9: 92219771-92221411
Island


cg03250393
chr19: 41735107
AXL.GENEBODY
F
chr19: 41732006-41732556
S_Shelf


cg03436967
chr7: 147207052
MIR54814.GENEBODY
F


cg03549571
chr12: 49488198
DHH.EXON1
R
chr12: 49487963-49488202
Island


cg03832506
chrX: 53286187
IQSEC2.GENEBODY
R
chrX: 53283829-53284038
S_Shelf


cg04328477
chr16: 68270258
ESRP2.TSS200
F
chr16: 68269010-68272143
Island


cg05171933
chr5: 147205668
SPINK1.GENEBODY
F


cg06193043
chr1: 11908199
NPPA.TSS1500
F


cg06205574
chr12: 23858674
SOX5.GENEBODY
F


cg06671964
chr6: 32052105
TNXB.GENEBODY
F
chr6: 32055067-32055601
N_Shelf


cg06723863
chr16: 68270129
ESRP2.EXON1
F
chr16: 68269010-68272143
Island


cg07896312
chr8: 22409062
SORBS3.TSS200
R
chr8: 22408672-22409635
Island


cg08416875
chr6: 119669226
MAN1A1.GENEBODY
R
chr6: 119669589-119671424
N_Shore


cg08575922
chr12: 49488082
DHH.EXON1
R
chr12: 49487963-49488202
Island


cg09807148
chr17: 34122069
MMP28.GENEBODY
F
chr17: 34122024-34122801
Island


cg09990600
chr7: 1596103
TMEM184A.TSS200
R


cg10030250
chr16: 55540152
MMP2.UTR3
F
chr16: 55542920-55543274
N_Shelf


cg10131879
chr7: 8011594
GLCCI1.GENEBODY
F
chr7: 8008097-8009495
S_Shelf


cg10688790
chr7: 147591961
MIR548F3.TSS1500
R


cg11384924
chr6: 33160224
COL11A2.UTR5
F
chr6: 33159991-33160263
Island


cg11664251
chr2: 149634581
KIF5C.GENEBODY
R
chr2: 149632682-149633882
S_Shore


cg11989343
chr13: 53287193
LECT1.GENEBODY
R


cg12444861
chr6: 144386275
PLAGL1.TSS1500
F
chr6: 144384894-144385888
S_Shore


cg12626076
chr15: 92399195
SLCO3A1.GENEBODY
F
chr15: 92396013-92397682
S_Shore


cg13586420
chr6: 33160262
COL11A2.TSS200
F
chr6: 33159991-33160263
Island


cg13969788
chr9: 35689475
TPM2.GENEBODY
F
chr9: 35689610-35691101
N_Shore


cg14011070
chr1: 235811811
GNG4.UTR5
R
chr1: 235811841-235814066
N_Shore


cg14627974
chr7: 147188028
MIR54814.GENEBODY
F


cg15558616
chr3: 173630182
NLGN1.GENEBODY
R


cg15678504
chr8: 10262159
MSRA.GENEBODY
R
chr8: 10261900-10262222
Island


cg15712559
chr20: 58180616
PHACTR3.GENEBODY
F
chr20: 58179808-58180787
Island


cg15982299
chr6: 31097078
PSORS1C1.UTR5
F


cg16014168
chr12: 109729677
FOXN4.GENEBODY
F
chr12: 109729572-109729826
Island


cg16911349
chr19: 10406935
ICAM5.GENEBODY
R
chr19: 10406934-10407342
Island


cg18216587
chr7: 146019420
CNTNAP2.GENEBODY
F


cg18516816
chr19: 30165591
PLEKHF1.UTR3
F
chr19: 30164768-30165556
S_Shore


cg19047707
chr2: 233351525
ECEL1.UTR5
R
chr2: 233350278-233352974
Island


cg20010135
chr16: 30996822
HSD3B7.UTR5
F


cg20330126
chr22: 36125053
APOL5.UTR3
F


cg21446725
chr12: 49740996
DNAJC22.TSS200
R
chr12: 49738680-49740841
S_Shore


cg22857356
chr19: 8398590
KANK3.GENEBODY
R
chr19: 8397958-8400461
Island


cg23097961
chr19: 49055412
SULT2B1.TSS200
F


cg23344395
chr3: 192634002
C3orf59.GENEBODY
R
chr3: 192634309-192635967
N_Shore


cg23623622
chr6: 30139880
TRIM15.GENEBODY
F
chr6: 30139718-30140263
Island


cg23764900
chr11: 8616102
STK33.TSS1500
R
chr11: 8615397-8615889
S_Shore


cg23883945
chr7: 36749772
AOAH.GENEBODY
F


cg23937993
chr11: 10477847
AMPD3.EXON1
F


cg24021846
chr7: 103556529
RELN.GENEBODY
F


cg24952408
chr6: 29696264
LOC285830.GENEBODY
F


cg25934371
chr3: 63427866
SYNPR.GENEBODY
F


cg27023555
chr2: 233351735
ECEL1.UTR5
R
chr2: 233350278-233352974
Island


cg27108362
chr12: 49488554
DHH.UTR5
F
chr12: 49487963-49488202
S_Shore


cg27181765
chr6: 33160250
COL11A2.TSS200
F
chr6: 33159991-33160263
Island


cg01635061
chr6: 33160234
COL11A2.UTR5
F
chr6: 33159991-33160263
Island


cg02582213
chr16: 89441654
ANKRD11.UTR5
F
chr16: 89438503-89438850
S_Shelf


cg02628840
chr21: 46860579
COL18A1.GENEBODY
R
chr21: 46860366-46860628
Island


cg06712559
chr1: 968395
AGRN.GENEBODY
F
chr1: 967966-970238
Island


cg09235583
chr6: 30711141
IER3.UTR3
F
chr6: 30710307-30712440
Island


cg20931195
chr17: 708009
NXN.GENEBODY
F
chr17: 708319-708598
N_Shore


cg25549619
chr5: 147154246
JAKMIP2.UTR5
F


cg27480819
chr12: 23686149
SOX5.UTR3
R


cg00201445
chr3: 192634310
C3orf59.GENEBODY
R
chr3: 192634309-192635967
Island


cg00650953
chr7: 147500503
CNTNAP2.GENEBODY
R


cg00698688
chr19: 49055432
SULT2B1.EXON1
F


cg00965643
chr1: 32674817
DCDC2B.EXON1
F
chr1: 32670569-32671885
S_Shelf


cg00974598
chr19: 44223902
IRGC.GENEBODY
R
chr19: 44222858-44223943
Island


cg01030534
chr7: 143579698
FAM115A.UTR5
F
chr7: 143582125-143582610
N_Shelf


cg01243297
chr6: 33160292
COL11A2.TSS200
F
chr6: 33160945-33161337
N_Shore


cg02633149
chr17: 81042782
METRNL.GENEBODY
R
chr17: 81042626-81043244
Island


cg03039843
chr19: 49055390
SULT2B1.TSS200
R


cg03485217
chr4: 10686300
CLNK.EXON1
R


cg03607415
chr5: 89881642
GPR98.GENEBODY
R


cg03761471
chr7: 143077178
ZYX.TSS1500
F
chr7: 143077469-143079169
N_Shore


cg03936135
chr16: 86371248
LOC732275.GENEBODY
F


cg04601383
chr19: 6713459
C3.GENEBODY
R
chr19: 6710625-6710828
S_Shelf


cg05681757
chr12: 32655034
FGD4.TSS200
R


cg06822340
chr7: 147355839
CNTNAP2.GENEBODY
R


cg06852032
chr17: 25976191
LGALS9.GENEBODY
F


cg07001963
chr10: 44879465
CXCL12.GENEBODY
R
chr10: 44879714-44882391
N_Shore


cg07095230
chr17: 59480730
TBX2.GENEBODY
F
chr17: 59473060-59483266
Island


cg07152605
chr1: 164793520
PBX1.GENEBODY
R


cg07270851
chr11: 65779332
CST6.TSS200
F
chr11: 65779311-65779767
Island


cg07287698
chr12: 97957454
MIR135A2.TSS200
F


cg08787401
chr2: 222383520
EPHA4.GENEBODY
F


cg09225457
chr7: 8479893
NXPH1.GENEBODY
R
chr7: 8481974-8482762
N_Shelf


cg09932135
chr1: 11750569
MAD2L2.UTR5
F
chr1: 11750701-11752651
N_Shore


cg11904429
chr19: 6592554
CD70.TSS1500
F
chr19: 6590340-6591072
S_Shore


cg12197421
chr6: 30653736
KIAA1949.GENEBODY
F
chr6: 30654392-30654934
N_Shore


cg12747860
chr6: 3229027
TUBB2B.TSS1500
R
chr6: 3227025-3229688
Island


cg12805420
chr17: 7165840
CLDN7.TSS200
R
chr17: 7164285-7166245
Island


cg12967164
chr7: 1753637
ELFN1.UTR5
F
chr7: 1753446-1753706
Island


cg13094252
chr8: 104153753
C8orf56.TSS200
R
chr8: 104152726-104153390
S_Shore


cg13673837
chr19: 15306670
NOTCH3.GENEBODY
F
chr19: 15306243-15307111
Island


cg14282850
chr10: 123924917
TACC2.GENEBODY
F
chr10: 123922850-123923542
S_Shore


cg14347177
chr11: 65779330
CST6.TSS200
F
chr11: 65779311-65779767
Island


cg14574369
chr12: 57483631
NAB2.GENEBODY
R
chr12: 57480797-57483116
S_Shore


cg14663984
chr1: 969042
AGRN.GENEBODY
F
chr1: 967966-970238
Island


cg15633699
chr1: 1356728
LOC441869.TSS200
F
chr1: 1355159-1356000
S_Shore


cg16663570
chr8: 22014724
LGI3.TSS1500
F
chr8: 22014152-22014559
S_Shore


cg16713727
chr1: 16062720
SLC25A34.TSS200
R


cg17928920
chr1: 968558
AGRN.GENEBODY
R
chr1: 967966-970238
Island


cg18425731
chr2: 158184641
ERMN.TSS1500
F


cg19092045
chr13: 54887369
MIR1297.TSS1500
R


cg19244428
chr6: 3229233
TUBB2B.TSS1500
R
chr6: 3227025-3229688
Island


cg19791630
chr19: 6772811
VAV1.UTR5
F


cg20308663
chr13: 100523121
CLYBL.GENEBODY
F


cg20561300
chr15: 93189780
FAM174B.GENEBODY
R


cg21131024
chr8: 104153643
C8orf56.TSS200
F
chr8: 104152726-104153390
S_Shore


cg21422016
chr7: 1753659
ELFN1.UTR5
R
chr7: 1753446-1753706
Island


cg22156128
chr3: 10327453
GHRL.GENEBODY
R


cg22431093
chr12: 32654992
FGD4.TSS200
R


cg23049291
chr1: 165204745
LMX1A.GENEBODY
F
chr1: 165204501-165205507
Island


cg26080567
chr21: 37536137
DOPEY2.TSS1500
R


cg26190885
chr19: 45409005
APOE.TSS200
F
chr19: 45411720-45412600
N_Shelf


cg26638341
chr19: 1800126
ATP8B3.GENEBODY
F
chr19: 1799934-1800248
Island


cg26737640
chr19: 6587584
CD70.GENEBODY
F
chr19: 6590340-6591072
N_Shelf


cg26946905
chr16: 89441595
ANKRD11.UTR5
F
chr16: 89438503-89438850
S_Shelf


cg26993132
chr16: 89239499
CDH15.GENEBODY
F
chr16: 89237944-89238331
S_Shore


cg27082921
chr19: 1800150
ATP8B3.GENEBODY
R
chr19: 1799934-1800248
Island


cg02349785
chr11: 65778967
CST6.TSS1500
R
chr11: 65779311-65779767
N_Shore


cg02576092
chr1: 27668556
SYTL1.EXON1
R


cg04327181
chr11: 65779526
CST6.EXON1
F
chr11: 65779311-65779767
Island


cg04626868
chr12: 23999034
SOX5.GENEBODY
R


cg05601974
chr7: 150941389
SMARCD3.GENEBODY
F
chr7: 150942304-150943033
N_Shore


cg09482611
chr11: 65779263
CST6.TSS200
R
chr11: 65779311-65779767
N_Shore


cg14452346
chr5: 147212032
SPINK1.TSS1500
F


cg19296556
chr19: 1802918
ATP8B3.GENEBODY
F
chr19: 1799934-1800248
S_Shelf


cg24478779
chr2: 6110966
LOC150622.GENEBODY
R


cg04016660
chr16: 85075232
KIAA0513.UTR5
R


cg00107982
chr22: 37813098
ELFN2.UTR5
F
chr22: 37815803-37816477
N_Shelf


cg00135874
chr2: 210493473
MAP2.UTR5
R


cg00464796
chr15: 53852614
WDR72.GENEBODY
F


cg01084435
chr16: 58535556
NDRG4.GENEBODY
F
chr16: 58535040-58535596
Island


cg03992611
chr15: 92397873
SLCO3A1.GENEBODY
R
chr15: 92396013-92397682
S_Shore


cg04080448
chr12: 97924358
RMST.GENEBODY
F


cg05393025
chr1: 20141781
RNF186.TSS200
R


cg06189653
chr5: 176873332
PRR7.TSS1500
R
chr5: 176873349-176874737
N_Shore


cg06705685
chr2: 8116961
LOC339788.TSS200
F


cg08151612
chr19: 49055438
SULT2B1.EXON1
R


cg08966208
chr11: 1769409
HCCA2.GENEBODY
F
chr11: 1768979-1770712
Island


cg11406274
chr6: 29856564
HLA-H.GENEBODY
F
chr6: 29855295-29856565
Island


cg11736020
chr6: 30651511
KIAA1949.GENEBODY
R
chr6: 30654392-30654934
N_Shelf


cg11920519
chr20: 33135025
MAP1LC3A.UTR5
R


cg12570246
chr7: 36959356
MIR1200.TSS1500
F


cg12732715
chr1: 148929740
LOC645166.TSS1500
F


cg12781794
chr11: 118505740
PHLDB1.GENEBODY
F
chr11: 118505508-118505741
Island


cg13729891
chr17: 7108468
DLG4.GENEBODY
F
chr17: 7108304-7108654
Island


cg13951572
chr8: 22409000
SORBS3.TSS1500
F
chr8: 22408672-22409635
Island


cg14089943
chr10: 103990076
PITX3.UTR3
R
chr10: 103990213-103991829
N_Shore


cg14279361
chr19: 6721955
C3.TSS1500
R


cg14397690
chr15: 60688948
ANXA2.UTR5
F
chr15: 60689749-60690430
N_Shore


cg14492061
chr3: 63637129
SNTN.TSS1500
R


cg14899716
chr1: 42846987
RIMKLA.GENEBODY
F
chr1: 42845978-42846988
Island


cg15249911
chr19: 41634046
CYP2F1.UTR3
R
chr19: 41633776-41634047
Island


cg15507500
chr19: 17605696
SLC27A1.GENEBODY
F
chr19: 17607983-17608406
N_Shelf


cg16094352
chr14: 24642317
REC8.GENEBODY
R
chr14: 24641053-24642220
S_Shore


cg16318112
chr1: 969254
AGRN.GENEBODY
F
chr1: 967966-970238
Island


cg16706099
chr11: 100590197
FLJ32810.GENEBODY
F


cg17058616
chr17: 73102145
SLC16A5.UTR3
R
chr17: 73105229-73106667
N_Shelf


cg17610929
chr2: 220379044
ACCN4.UTR5
R
chr2: 220377743-220377946
S_Shore


cg17826168
chr19: 6464103
CRB3.TSS200
F
chr19: 6463991-6464780
Island


cg17945153
chr6: 41978288
CCND3.UTR5
R


cg19260567
chr7: 147303836
CNTNAP2.GENEBODY
F


cg20855296
chr17: 16255560
CENPV.GENEBODY
R
chr17: 16255618-16257148
N_Shore


cg21061582
chr18: 44498047
PIAS2.TSS1500
F
chr18: 44496910-44497832
S_Shore


cg21238061
chr9: 104036809
LPPR1.GENEBODY
R


cg22365276
chr15: 60688622
ANXA2.UTR5
R
chr15: 60689749-60690430
N_Shore


cg22376856
chr1: 204643556
LRRN2.UTR5
R


cg22862634
chr11: 62369728
EML3.UTR3
R
chr11: 62368454-62370491
Island


cg23214395
chr1: 20141778
RNF186.TSS200
R


cg23265500
chr14: 65016591
C14orf50.TSS200
R
chr14: 65016516-65016909
Island


cg23912509
chr12: 97957406
MIR135A2.TSS200
F


cg24556026
chr9: 36258971
GNE.TSS1500
F
chr9: 36258170-36258886
S_Shore


cg24723883
chr19: 2608495
GNG7.UTR5
F
chr19: 2607725-2607967
S_Shore


cg25124058
chr12: 97886218
RMST.GENEBODY
F


cg26633373
chr19: 54377836
MYADM.UTR3
R
chr19: 54377172-54377441
S_Shore


cg26660800
chr17: 59480926
TBX2.GENEBODY
F
chr17: 59473060-59483266
Island


cg00187437
chr6: 31089157
CDSN.TSS1500
R


cg00294550
chr10: 62144786
ANK3.GENEBODY
F


cg02447471
chr7: 95537015
DYNC1I1.GENEBODY
F


cg11243173
chr12: 23999045
SOX5.GENEBODY
R


cg14894216
chr11: 65794352
CATSPER1.TSS1500
R


cg17295739
chr6: 32049513
TNXB.GENEBODY
R
chr6: 32046815-32047094
S_Shelf


cg24283921
chr11: 10477461
AMPD3.TSS200
F


cg26070020
chr1: 165201385
LMX1A.GENEBODY
F
chr1: 165204501-165205507
N_Shelf


cg27248041
chr6: 93992464
EPHA7.GENEBODY
F


cg03514404
chr7: 143579665
FAM115A.UTR5
F
chr7: 143582125-143582610
N_Shelf


cg00151914
chr17: 34058550
RASL10B.TSS200
R
chr17: 34058549-34058778
Island


cg00721771
chr3: 59903821
FHIT.GENEBODY
F


cg00784153
chr19: 10077007
COL5A3.GENEBODY
R
chr19: 10077031-10077444
N_Shore


cg00957688
chr1: 36183672
C1orf216.UTR5
F
chr1: 36184248-36184774
N_Shore


cg01110620
chr12: 113573312
RASAL1.UTR5
F
chr12: 113572977-113573758
Island


cg01538731
chr16: 87757018
KLHDC4.GENEBODY
F
chr16: 87754008-87754285
S_Shelf


cg01794802
chr6: 31096931
PSORS1C1.UTR5
R


cg02004418
chr2: 45236740
SIX2.TSS200
R
chr2: 45235511-45237792
Island


cg02227919
chr2: 171569132
LOC440925.GENEBODY
R
chr2: 171569877-171573904
N_Shore


cg02849309
chr6: 144386280
PLAGL1.TSS1500
F
chr6: 144384894-144385888
S_Shore


cg02916272
chr11: 1769443
HCCA2.GENEBODY
F
chr11: 1768979-1770712
Island


cg03153115
chr19: 2604559
GNG7.UTR5
F
chr19: 2607725-2607967
N_Shelf


cg03207915
chr6: 119669112
MAN1A1.GENEBODY
F
chr6: 119669589-119671424
N_Shore


cg03546687
chr16: 2198080
RAB26.TSS1500
R
chr16: 2198455-2199129
N_Shore


cg04396998
chr19: 49376722
PPP1R15A.GENEBODY
R
chr19: 49375484-49375928
S_Shore


cg04475868
chr16: 86380594
LOC732275.TSS1500
F


cg04742671
chr19: 54781049
LILRB2.GENEBODY
R


cg05301811
chr1: 20813666
CAMK2N1.TSS1500
F
chr1: 20810462-20813511
S_Shore


cg05484788
chr20: 58180357
PHACTR3.GENEBODY
F
chr20: 58179808-58180787
Island


cg06303936
chr3: 172711298
SPATA16.GENEBODY
F


cg07629125
chr13: 58299015
PCDH17.GENEBODY
R


cg08247297
chr21: 46917541
COL18A1.GENEBODY
F
chr21: 46918188-46918410
N_Shore


cg08269485
chr11: 1769382
HCCA2.GENEBODY
F
chr11: 1768979-1770712
Island


cg08550882
chr11: 12308354
MICALCL.TSS200
R


cg09708598
chr13: 54887314
MIR1297.TSS1500
F


cg10303653
chr6: 32049516
TNXB.GENEBODY
R
chr6: 32046815-32047094
S_Shelf


cg10560147
chr11: 65779335
CST6.TSS200
F
chr11: 65779311-65779767
Island


cg12432038
chr1: 247275735
C1orf229.TSS200
R
chr1: 247274585-247275757
Island


cg13064679
chr6: 32049953
TNXB.GENEBODY
R
chr6: 32046815-32047094
S_Shelf


cg13095737
chr5: 177034964
B4GALT7.GENEBODY
R
chr5: 177035351-177035660
N_Shore


cg15005677
chr11: 45918197
MAPK8IP1.GENEBODY
R
chr11: 45921387-45922167
N_Shelf


cg15144888
chr11: 128760367
KCNJ5.TSS1500
F
chr11: 128760441-128761233
N_Shore


cg15323252
chr8: 22436420
PDLIM2.TSS1500
R
chr8: 22436295-22437076
Island


cg16317181
chr10: 85954559
PCDH21.EXON1
R
chr10: 85954199-85955303
Island


cg17765324
chr12: 16359122
SLC15A5.GENEBODY
F


cg18320766
chr19: 55598782
EPS8L1.GENEBODY
R
chr19: 55597977-55598887
Island


cg19455335
chr8: 22457658
C8orf58.GENEBODY
R
chr8: 22457123-22457753
Island


cg19961803
chr11: 65554928
OVOL1.EXON1
F
chr11: 65553749-65555573
Island


cg20383948
chr21: 46898137
COL18A1.GENEBODY
R
chr21: 46897841-46898158
Island


cg21475065
chr7: 147336337
CNTNAP2.GENEBODY
R


cg22153696
chr4: 186389425
CCDC110.GENEBODY
F
chr4: 186392574-186393184
N_Shelf


cg22287800
chr7: 8634300
NXPH1.GENEBODY
F


cg24042496
chr11: 117497929
DSCAML1.GENEBODY
R


cg24990327
chr7: 147591897
MIR548F3.TSS1500
R


cg25317941
chr2: 233351153
ECEL1.GENEBODY
R
chr2: 233350278-233352974
Island


cg26104986
chr11: 75275303
SERPINH1.UTR5
F
chr11: 75272950-75273616
S_Shore


cg27579097
chr16: 734844
JMJD8.TSS1500
R
chr16: 729438-735815
Island


cg04486528
chr7: 147727995
MIR548F3.GENEBODY
F


cg07047570
chr20: 20350813
INSM1.EXON1
F
chr20: 20344400-20350605
S_Shore


cg07912147
chr12: 26138851
RASSF8.UTR5
R


cg09246103
chr1: 8456466
RERE.UTR5
R


cg09247061
chr16: 88571844
ZFPM1.GENEBODY
F
chr16: 88573285-88573489
N_Shore


cg09365529
chr1: 75140289
C1orf173.TSS1500
F


cg14950855
chr12: 49740781
DNAJC22.TSS1500
F
chr12: 49738680-49740841
Island


cg15262242
chr17: 47301741
PHOSPHO1.GENEBODY
R
chr17: 47301545-47302477
Island


cg15802396
chr17: 7108305
DLG4.GENEBODY
R
chr17: 7108304-7108654
Island


cg16182479
chr17: 41832466
SOST.UTR3
R
chr17: 41832717-41833195
N_Shore


cg16630229
chr6: 33160604
COL11A2.TSS1500
F
chr6: 33160945-33161337
N_Shore


cg18395327
chr2: 220379109
ACCN4.EXON1
R
chr2: 220377743-220377946
S_Shore


cg19822502
chr6: 97456581
KLHL32.GENEBODY
F


cg22189307
chr11: 61061699
VWCE.GENEBODY
R
chr11: 61061751-61063063
N_Shore


cg23619910
chr11: 10477452
AMPD3.TSS200
R


cg24155984
chr5: 66127678
MAST4.GENEBODY
F


cg26578983
chr16: 85075249
KIAA0513.UTR5
R


cg00691368
chr6: 30909820
DPCR1.GENEBODY
F


cg00988129
chr8: 75232556
JPH1.GENEBODY
R
chr8: 75232649-75234101
N_Shore


cg03716590
chr7: 95435309
DYNC1I1.GENEBODY
R


cg04770813
chr6: 33160297
COL11A2.TSS200
F
chr6: 33160945-33161337
N_Shore


cg05273302
chr19: 2095560
C19orf36.TSS1500
F
chr19: 2095395-2095727
Island


cg06212760
chr1: 46664937
POMGNT1.GENEBODY
R
chr1: 46668821-46669258
N_Shelf


cg07308243
chr16: 85074963
KIAA0513.UTR5
R


cg07409292
chr4: 90228685
GPRIN3.UTR5
R
chr4: 90228714-90229010
N_Shore


cg08531687
chr5: 89968232
GPR98.GENEBODY
F


cg09335647
chr7: 147097440
MIR548I4.GENEBODY
F


cg10332715
chr1: 245017736
HNRNPU.UTR3
F


cg10383447
chr16: 58535093
NDRG4.GENEBODY
F
chr16: 58535040-58535596
Island


cg10632765
chr19: 6534916
TNFSF9.GENEBODY
F
chr19: 6534759-6535079
Island


cg12046414
chr2: 220379199
ACCN4.EXON1
R
chr2: 220377743-220377946
S_Shore


cg12489353
chr19: 48231499
EHD2.GENEBODY
F
chr19: 48229072-48229507
S_Shore


cg13455326
chr19: 10043341
OLFM2.GENEBODY
R
chr19: 10046824-10047067
N_Shelf


cg14098532
chr3: 111717874
TAGLN3.TSS200
F


cg14478768
chr19: 1083429
HMHA1.GENEBODY
F
chr19: 1082576-1083430
Island


cg15939253
chr11: 66049932
CNIH2.GENEBODY
F
chr11: 66049750-66050229
Island


cg16678522
chr20: 32149963
CBFA2T2.GENEBODY
F


cg17831934
chr7: 147264850
CNTNAP2.GENEBODY
R


cg17894318
chr3: 181441384
SOX2OT.GENEBODY
F
chr3: 181444409-181445000
N_Shelf


cg18512948
chr14: 24641706
REC8.EXON1
R
chr14: 24641053-24642220
Island


cg19506253
chr2: 158301839
CYTIP.TSS1500
F


cg19702383
chr12: 97885575
RMST.GENEBODY
F


cg19799744
chr6: 46138963
ENPP5.TSS1500
R


cg19924334
chr20: 62197682
PRIC285.GENEBODY
F
chr20: 62193966-62198985
Island


cg20716515
chr19: 44172263
PLAUR.GENEBODY
F
chr19: 44172916-44173252
N_Shore


cg21389753
chr17: 59480674
TBX2.GENEBODY
F
chr17: 59473060-59483266
Island


cg22881677
chr12: 63195695
PPM1H.GENEBODY
R
chr12: 63195657-63195909
Island


cg24743778
chr2: 220379058
ACCN4.UTR5
R
chr2: 220377743-220377946
S_Shore


cg25242557
chr11: 31833264
PAX6.TSS1500
R
chr11: 31831620-31839038
Island


cg25540824
chr6: 30139686
TRIM15.GENEBODY
F
chr6: 30139718-30140263
N_Shore


cg25587092
chr6: 32076906
TNXB.UTR5
R


cg27125631
chr17: 47654653
NXPH3.GENEBODY
F
chr17: 47652789-47653078
S_Shore


cg00936309
chr6: 33141824
COL11A2.GENEBODY
F


cg01116568
chr11: 10476529
AMPD3.TSS200
R
chr11: 10472000-10472857
S_Shelf


cg01594262
chr19: 38806145
YIF1B.GENEBODY
R
chr19: 38806485-38806747
N_Shore


cg02355653
chr6: 29710830
LOC285830.GENEBODY
R


cg02452416
chr6: 33160450
COL11A2.TSS1500
R
chr6: 33160945-33161337
N_Shore


cg03054529
chr7: 30029938
SCRN1.TSS1500
F
chr7: 30028518-30029822
S_Shore


cg04138361
chr6: 33160304
COL11A2.TSS200
F
chr6: 33160945-33161337
N_Shore


cg04403415
chr12: 124991087
NCOR2.UTR5
F


cg07387813
chr3: 40499408
RPL14.GENEBODY
R
chr3: 40498639-40499260
S_Shore


cg08858649
chr6: 30139903
TRIM15.GENEBODY
R
chr6: 30139718-30140263
Island


cg09537107
chr19: 48897008
GRIN2D.TSS1500
F
chr19: 48896890-48897199
Island


cg12049787
chr19: 45409080
APOE.EXON1
R
chr19: 45411720-45412600
N_Shelf


cg12077433
chr3: 159600838
SCHIP1.GENEBODY
F


cg12108912
chr2: 120435949
TMEM177.TSS1500
R
chr2: 120436530-120437010
N_Shore


cg12643732
chr5: 691580
TPPP.UTR5
F
chr5: 692681-694377
N_Shore


cg12776156
chr11: 848044
TSPAN4.UTR5
F
chr11: 849087-850982
N_Shore


cg13212283
chr12: 57632120
NDUFA4L2.UTR5
F
chr12: 57631932-57634578
Island


cg14507088
chr9: 130690399
PIP5KL1.GENEBODY
R
chr9: 130689378-130690215
S_Shore


cg15622556
chr1: 12251820
TNFRSF1B.GENEBODY
F
chr1: 12251777-12251985
Island


cg16458153
chr6: 33160192
COL11A2.UTR5
R
chr6: 33159991-33160263
Island


cg16523839
chr19: 10077134
COL5A3.GENEBODY
R
chr19: 10077031-10077444
Island


cg16825133
chr19: 675672
FSTL3.TSS1500
R
chr19: 675671-675881
Island


cg16860712
chr19: 48244461
EHD2.GENEBODY
F
chr19: 48244150-48244693
Island


cg18636319
chr4: 26492206
CCKAR.TSS200
R


cg18788725
chr19: 45512122
RELB.GENEBODY
R
chr19: 45515163-45515560
N_Shelf


cg19776793
chr17: 79225974
SLC38A10.GENEBODY
F


cg20333836
chr1: 156215418
PAQR6.GENEBODY
R
chr1: 156215368-156215899
Island


cg20639396
chr6: 128839906
PTPRK.GENEBODY
R
chr6: 128840158-128842126
N_Shore


cg20672284
chr12: 23998921
SOX5.GENEBODY
R


cg21009420
chr7: 146484504
CNTNAP2.GENEBODY
R


cg23337031
chr2: 236416064
AGAP1.GENEBODY
F


cg23627353
chr8: 102669360
GRHL2.GENEBODY
F


cg26674800
chr17: 7108653
DLG4.GENEBODY
F
chr17: 7108304-7108654
Island


cg26853536
chr12: 125399964
UBC.TSS1500
F
chr12: 125398558-125399899
S_Shore


cg00126034
chr17: 44896162
WNT3.TSS200
F
chr17: 44895800-44897025
Island


cg00758881
chr16: 58534681
NDRG4.GENEBODY
R
chr16: 58535040-58535596
N_Shore


cg01029347
chr14: 77606335
ZDHHC22.UTR5
R
chr14: 77605885-77608304
Island


cg02010738
chr19: 2095466
C19orf36.TSS1500
R
chr19: 2095395-2095727
Island


cg03300078
chr11: 1769522
HCCA2.GENEBODY
F
chr11: 1768979-1770712
Island


cg04663692
chr12: 97885669
RMST.GENEBODY
R


cg04694991
chr10: 97219665
SORBS1.UTR5
F


cg06998765
chr14: 75389618
RPS6KL1.TSS1500
F
chr14: 75389712-75390133
N_Shore


cg07304692
chr2: 100939045
LONRF2.UTR5
R
chr2: 100937779-100939059
Island


cg07775371
chr16: 1922155
C16orf73.UTR5
F
chr16: 1921897-1922426
Island


cg09271709
chr2: 50863603
NRXN1.GENEBODY
R


cg09327981
chr7: 95455393
DYNC111.GENEBODY
F


cg09750510
chr6: 25761690
SLC17A4.UTR5
R


cg10098010
chr6: 138483709
KIAA1244.GENEBODY
F
chr6: 138482534-138483710
Island


cg10599438
chr19: 844589
PRTN3.GENEBODY
F
chr19: 846011-846435
N_Shore


cg11565299
chr6: 30139478
TRIM15.GENEBODY
F
chr6: 30139718-30140263
N_Shore


cg11775828
chr2: 169100915
STK39.GENEBODY
F
chr2: 169102950-169104454
N_Shelf


cg12281657
chr14: 65016595
C14orf50.TSS200
R
chr14: 65016516-65016909
Island


cg12317456
chr16: 55512868
MMP2.TSS1500
R
chr16: 55513220-55513526
N_Shore


cg12699599
chr15: 40643142
PHGR1.TSS200
R


cg12934382
chr3: 51741135
GRM2.EXON1
F
chr3: 51740740-51741413
Island


cg13313836
chr15: 60687284
ANXA2.UTR5
R
chr15: 60689749-60690430
N_Shelf


cg14307471
chr18: 31432117
NOL4.UTR3
F


cg15174248
chr5: 149669674
CAMK2A.TSS1500
F


cg17176573
chr11: 120110887
POU2F3.TSS200
R
chr11: 120110497-120110719
S_Shore


cg19419650
chr19: 7929643
EVI5L.UTR3
F
chr19: 7926590-7928752
S_Shore


cg19519964
chr2: 223290012
SGPP2.GENEBODY
F
chr2: 223288922-223290013
Island


cg19722656
chr6: 119669372
MAN1A1.GENEBODY
R
chr6: 119669589-119671424
N_Shore


cg20971970
chr12: 57632495
NDUFA4L2.UTR5
R
chr12: 57631932-57634578
Island


cg21492961
chr5: 90036436
GPR98.GENEBODY
R


cg21759280
chr19: 6534936
TNFSF9.GENEBODY
F
chr19: 6534759-6535079
Island


cg21958743
chr12: 79832188
SYT1.GENEBODY
F


cg23084895
chr1: 214162854
PROX1.UTR5
R
chr1: 214160798-214161034
S_Shore


cg25746092
chr6: 31081617
PSORS1C1.TSS1500
F


cg26576206
chr19: 1064938
ABCA7.GENEBODY
F
chr19: 1064897-1065191
Island


cg26839863
chr10: 21814793
C10orf140.TSS200
R
chr10: 21814786-21815716
Island


cg26995690
chr13: 36346376
DCLK1.UTR3
F


cg00293644
chr1: 32674341
DCDC2B.TSS1500
R
chr1: 32670569-32671885
S_Shelf


cg00407245
chr19: 55598874
EPS8L1.GENEBODY
F
chr19: 55597977-55598887
Island


cg00848007
chr12: 68553396
IFNG.EXON1
F


cg00956142
chr1: 28765031
PHACTR4.GENEBODY
F


cg01666490
chr8: 102984290
NCALD.UTR5
R


cg01783706
chr12: 49739991
DNAJC22.TSS1500
R
chr12: 49738680-49740841
Island


cg01902845
chr1: 214170993
PROX1.GENEBODY
R


cg02275396
chr19: 15554549
WIZ.GENEBODY
R
chr19: 15550849-15551059
S_Shelf


cg03186999
chr17: 7165420
CLDN7.UTR5
F
chr17: 7164285-7166245
Island


cg05257528
chr19: 846179
PRTN3.GENEBODY
F
chr19: 846011-846435
Island


cg06371583
chr19: 2581343
GNG7.UTR5
F
chr19: 2578956-2579746
S_Shore


cg06764736
chr12: 23998997
SOX5.GENEBODY
F


cg07299645
chr7: 147256263
MIR548I4.TSS1500
F


cg07475922
chr19: 10122694
RDH8.TSS1500
R
chr19: 10120750-10121231
S_Shore


cg08753391
chr6: 32049622
TNXB.GENEBODY
R
chr6: 32046815-32047094
S_Shelf


cg08897422
chr7: 8666902
NXPH1.GENEBODY
F


cg09588360
chr2: 54785795
SPTBN1.UTR5
R
chr2: 54785026-54785969
Island


cg10357885
chr19: 10122000
COL5A3.TSS1500
R
chr19: 10120750-10121231
S_Shore


cg11289677
chr6: 32049829
TNXB.GENEBODY
R
chr6: 32046815-32047094
S_Shelf


cg11620475
chr5: 135529232
LOC389332.TSS1500
R
chr5: 135527056-135528978
S_Shore


cg11742103
chr11: 62369870
EML3.UTR3
R
chr11: 62368454-62370491
Island


cg13500113
chr2: 216947149
TMEM169.UTR5
R
chr2: 216946324-216946734
S_Shore


cg13711424
chr14: 65017091
C14orf50.GENEBODY
R
chr14: 65016516-65016909
S_Shore


cg14025053
chr8: 104153637
C8orf56.TSS200
F
chr8: 104152726-104153390
S_Shore


cg15159069
chr3: 192634089
C3orf59.GENEBODY
F
chr3: 192634309-192635967
N_Shore


cg16573136
chr12: 49740639
DNAJC22.TSS1500
F
chr12: 49738680-49740841
Island


cg16663341
chr18: 42327562
SETBP1.GENEBODY
R
chr18: 42324454-42324966
S_Shelf


cg17617491
chr19: 2607726
GNG7.UTR5
R
chr19: 2607725-2607967
Island


cg17714703
chr19: 4912221
UHRF1.GENEBODY
R
chr19: 4909262-4910256
S_Shore


cg18010131
chr11: 10476620
AMPD3.TSS200
F
chr11: 10472000-10472857
S_Shelf


cg18168101
chr8: 104153627
C8orf56.TSS200
F
chr8: 104152726-104153390
S_Shore


cg18544974
chr3: 132842314
TMEM108.UTR5
R


cg18716083
chr5: 111506418
EPB41L4A.GENEBODY
F


cg19132462
chr11: 10476608
AMPD3.TSS200
R
chr11: 10472000-10472857
S_Shelf


cg19776942
chr1: 32714164
FAM167B.GENEBODY
F
chr1: 32713918-32714186
Island


cg19865770
chr1: 221510889
LOC400804.TSS1500
F


cg21171335
chr12: 122356390
WDR66.TSS200
F
chr12: 122356315-122356853
Island


cg21213853
chr3: 51741473
GRM2.UTR5
F
chr3: 51740740-51741413
S_Shore


cg21869609
chr19: 2291613
LINGO3.GENEBODY
R
chr19: 2289895-2291904
Island


cg22494035
chr15: 74537819
CCDC33.GENEBODY
R
chr15: 74537809-74538114
Island


cg22699676
chr2: 171569187
LOC440925.GENEBODY
R
chr2: 171569877-171573904
N_Shore


cg23601905
chr17: 17661060
RAI1.UTR5
F


cg23635599
chr19: 45281006
CBLC.TSS200
F
chr19: 45281133-45281355
N_Shore


cg23816247
chr8: 104153827
BAALC.GENEBODY
F
chr8: 104152726-104153390
S_Shore


cg24852713
chr19: 1083423
HMHA1.GENEBODY
F
chr19: 1082576-1083430
Island


cg27103348
chr21: 46321529
ITGB2.GENEBODY
R
chr21: 46321397-46321644
Island


cg27273866
chr12: 23919997
SOX5.GENEBODY
R


cg01337207
chr6: 32063835
TNXB.GENEBODY
F
chr6: 32063533-32065044
Island


cg02027561
chr6: 126110790
NCOA7.TSS1500
R
chr6: 126111537-126112480
N_Shore


cg03601354
chr8: 22408966
SORBS3.TSS1500
F
chr8: 22408672-22409635
Island


cg04015907
chr20: 825489
FAM110A.GENEBODY
F
chr20: 825267-826276
Island


cg05830220
chr16: 87757033
KLHDC4.GENEBODY
F
chr16: 87754008-87754285
S_Shelf


cg05957504
chr5: 124014639
ZNF608.GENEBODY
F


cg06198398
chr18: 44526707
KATNAL2.TSS200
R
chr18: 44526866-44527137
N_Shore


cg07312445
chr4: 40752151
NSUN7.UTR5
F
chr4: 40751842-40752493
Island


cg07524919
chr6: 32063901
TNXB.GENEBODY
F
chr6: 32063533-32065044
Island


cg10578482
chr8: 145111298
OPLAH.GENEBODY
R
chr8: 145111297-145111564
Island


cg10625931
chr12: 57632417
NDUFA4L2.UTR5
R
chr12: 57631932-57634578
Island


cg11632652
chr3: 174648902
NAALADL2.GENEBODY
F


cg13788097
chr3: 62467612
CADPS.GENEBODY
F


cg14188106
chr6: 32063895
TNXB.GENEBODY
F
chr6: 32063533-32065044
Island


cg15075267
chr19: 15306332
NOTCH3.GENEBODY
F
chr19: 15306243-15307111
Island


cg15857329
chr8: 144653570
C8orf73.GENEBODY
F
chr8: 144653774-144653976
N_Shore


cg16314401
chr2: 73144481
EMX1.TSS200
R
chr2: 73143055-73148260
Island


cg16924391
chr6: 29719411
IFITM4P.TSS1500
F
chr6: 29720381-29721101
N_Shore


cg16953031
chr3: 175064540
NAALADL2.GENEBODY
F


cg17693604
chr19: 3046805
TLE2.UTR5
F
chr19: 3047224-3047444
N_Shore


cg18612786
chr19: 45281236
CBLC.EXON1
R
chr19: 45281133-45281355
Island


cg20502039
chr7: 95804328
SLC25A13.GENEBODY
F


cg23288962
chr13: 35517516
NBEA.GENEBODY
R


cg23563443
chr8: 22408989
SORBS3.TSS1500
F
chr8: 22408672-22409635
Island


cg24836242
chr6: 30908579
DPCR1.TSS200
F


cg24847554
chr3: 57530606
DNAH12.TSS1500
F


cg27501759
chr3: 8809715
OXTR.GENEBODY
F
chr3: 8808961-8811280
Island


cg00378218
chr17: 1546841
SCARF1.GENEBODY
F
chr17: 1546742-1547324
Island


cg00637695
chr5: 121759771
SNCAIP.GENEBODY
R


cg01101058
chr14: 70235157
SFRS5.GENEBODY
F
chr14: 70233570-70234668
S_Shore


cg01645995
chr7: 92836152
HEPACAM2.GENEBODY
R


cg01664065
chr13: 102249040
ITGBL1.GENEBODY
R


cg02097532
chr3: 55673955
ERC2.UTR3
F


cg02105326
chr2: 239149142
HES6.TSS1500
R
chr2: 239147592-239149900
Island


cg02124724
chr21: 46875142
COL18A1.TSS1500
F
chr21: 46876168-46876752
N_Shore


cg02515354
chr7: 147256123
MIR548I4.TSS1500
F


cg02638523
chr2: 236548728
AGAP1.GENEBODY
R


cg02754084
chr12: 72338080
TPH2.GENEBODY
F


cg04657588
chr17: 72427543
GPRC5C.TSS200
F
chr17: 72426783-72428977
Island


cg05301383
chr2: 171569144
LOC440925.GENEBODY
F
chr2: 171569877-171573904
N_Shore


cg06201680
chr7: 151078646
WDR86.UTR3
R
chr7: 151078462-151079536
Island


cg07449967
chr8: 56987020
SNORD54.TSS1500
R
chr8: 56986556-56987308
Island


cg07471157
chr12: 49373263
WNT1.GENEBODY
R
chr12: 49371690-49375550
Island


cg08580631
chr2: 170220388
LRP2.TSS1500
R
chr2: 170220772-170221114
N_Shore


cg09114581
chr6: 32077103
TNXB.UTR5
R


cg10289744
chr3: 271185
CHL1.UTR5
R


cg10661054
chr2: 128422179
LIMS2.GENEBODY
R
chr2: 128421719-128422182
Island


cg10810657
chr5: 66203228
MAST4.GENEBODY
F


cg10970409
chr3: 42543566
VIPR1.TSS1500
F
chr3: 42542820-42544524
Island


cg11316386
chr1: 247275808
C1orf229.TSS200
R
chr1: 247274585-247275757
S_Shore


cg11642377
chr7: 8480779
NXPH1.GENEBODY
R
chr7: 8481974-8482762
N_Shore
















TABLE 6







Methylation markers for SCLC subtype classification using liquid biopsy













Methylation
Position
Associated



Relation to


Site
(GRCh 37)
Subgroup
Gene
Strand
CpG Island Name
CpG Island





cg00799539
chr12:103353183
SCLC-A
ASCL1.UTR3
R
chr12:103351579-103352695
S_Shore


cg04610718
chr12:103353362
SCLC-A
ASCL1.UTR3
F
chr12:103351579-103352695
S_Shore


cg10672201
chr12:103353320
SCLC-A
ASCL1.UTR3
F
chr12:103351579-103352695
S_Shore


cg17277939
chr12:70093008
SCLC-A
BEST3.EXON1
F


cg11201256
chr1:184403226
SCLC-A
C1orf21.UTR5
R


cg07639982
chr10:12555079
SCLC-A
CAMK1D.GENEBODY
F


cg01566028
chr9:123341267
SCLC-A
CDK5RAP2.GENEBODY
R
chr9:123342126-123342513
N_Shore


cg06043710
chr10:560371
SCLC-A
DIP2C.GENEBODY
F


cg01154505
chr2:112940409
SCLC-A
FBLN7.GENEBODY
F
chr2:112939287-112939563
S_Shore


cg09643186
chr14:65409452
SCLC-A
GPX2.EXON1
F


cg03817675
chr7:139299053
SCLC-A
HIPK2.GENEBODY
R


cg00090674
chr22:50446678
SCLC-A
IL17REL.UTR5
F
chr22:50448567-50449521
N_Shore


cg02639667
chr5:154092321
SCLC-A
LARP1.TSS200
F


cg22053861
chr11:65318683
SCLC-A
LTBP3.GENEBODY
R
chr11:65321225-65321823
N_Shelf


cg14338051
chr20:35924146
SCLC-A
MANBAL.UTR5
F


cg00794178
chr3:182897283
SCLC-A
MCF2L2.GENEBODY
F
chr3:182896920-182897381
Island


cg16860004
chr8:103137229
SCLC-A
NCALD.TSS1500
F
chr8:103135914-103136775
S_Shore


cg04317756
chr22:38085445
SCLC-A
NOL12.GENEBODY
R
chr22:38082302-38082796
S_Shelf


cg01942646
chr1:27240694
SCLC-A
NR0B2.TSS200
R


cg11249931
chr18:21796096
SCLC-A
OSBPL1A.GENEBODY
R


cg08279731
chr1:144988231
SCLC-A
PDE4DIP.GENEBODY
F


cg05161074
chr15:42289885
SCLC-A
PLA2G4E.GENEBODY
F


cg00773370
chr12:6483772
SCLC-A
SCNN1A.GENEBODY
R


cg07444408
chr4:141218466
SCLC-A
SCOC.UTR5
F


cg08758185
chr5:150849936
SCLC-A
SLC36A1.GENEBODY
F


cg27119612
chr15:57491001
SCLC-A
TCF12.GENEBODY
R


cg22904437
chr8:81064304
SCLC-A
TPD52.GENEBODY
R


cg04506569
chr2:234837977
SCLC-A
TRPM8.GENEBODY
F


cg04877165
chr2:174096031
SCLC-A
ZAK.GENEBODY
R


cg01610165
chr5:124071029
SCLC-A
ZNF608.GENEBODY
R


cg09248054
chr1:969257
SCLC-I
AGRN.GENEBODY
F
chr1:967966-970238
Island


cg02379560
chr4:40859280
SCLC-I
APBB2.GENEBODY
F
chr4:40858884-40859162
S_Shore


cg04917391
chr4:40859259
SCLC-I
APBB2.GENEBODY
F
chr4:40858884-40859162
S_Shore


cg05020685
chr4:40858965
SCLC-I
APBB2.GENEBODY
F
chr4:40858884-40859162
Island


cg06485940
chr4:40859293
SCLC-I
APBB2.GENEBODY
F
chr4:40858884-40859162
S_Shore


cg16364495
chr4:40859251
SCLC-I
APBB2.GENEBODY
F
chr4:40858884-40859162
S_Shore


cg05857126
chr16:52108007
SCLC-I
C16orf97.TSS200
F


cg13780782
chr16:52107988
SCLC-I
C16orf97.TSS200
F


cg02008691
chr16:52589450
SCLC-I
CASC16.GENEBODY
F


cg24664798
chr16:52640476
SCLC-I
CASC16.GENEBODY
R


cg17265693
chr17:7166490
SCLC-I
CLDN7.TSS1500
F
chr17:7164285-7166245
S_Shore


cg06508056
chr7:146594213
SCLC-I
CNTNAP2.GENEBODY
R


cg15932065
chr7:146470241
SCLC-I
CNTNAP2.GENEBODY
F


cg16405211
chr7:146897691
SCLC-I
CNTNAP2.GENEBODY
R


cg18804920
chr7:146572638
SCLC-I
CNTNAP2.GENEBODY
R


cg23889772
chr19:10077324
SCLC-I
COL5A3.GENEBODY
F
chr19:10077031-10077444
Island


cg07270851
chr11:65779332
SCLC-I
CST6.TSS200
F
chr11:65779311-65779767
Island


cg24238564
chr11:65779343
SCLC-I
CST6.TSS200
F
chr11:65779311-65779767
Island


cg03850035
chr2:222367110
SCLC-I
EPHA4.GENEBODY
R


cg02659920
chr11:726335
SCLC-I
EPS8L2.GENEBODY
F
chr11:725596-726870
Island


cg05651265
chr11:726367
SCLC-I
EPS8L2.GENEBODY
R
chr11:725596-726870
Island


cg10976861
chr2:239149937
SCLC-I
HES6.TSS1500
F
chr2:239147592-239149900
S_Shore


cg24127874
chr2:239149859
SCLC-I
HES6.TSS1500
F
chr2:239147592-239149900
Island


cg02365303
chr5:147052498
SCLC-I
JAKMIP2.UTR5
F


cg11799006
chr5:147101975
SCLC-I
JAKMIP2.UTR5
R


cg00336977
chr8:73826000
SCLC-I
KCNB2.GENEBODY
R


cg02125259
chr8:73559340
SCLC-I
KCNB2.GENEBODY
R


cg09433131
chr8:73480179
SCLC-I
KCNB2.GENEBODY
F


cg14865862
chr8:73632304
SCLC-I
KCNB2.GENEBODY
R


cg20136513
chr8:73711260
SCLC-I
KCNB2.GENEBODY
F


cg00378510
chr19:2291020
SCLC-I
LINGO3.GENEBODY
F
chr19:2289895-2291904
Island


cg06473097
chr8:73643063
SCLC-I
LOC101926908.TSS1500
R


cg23844705
chr1:164573835
SCLC-I
PBX1.GENEBODY
R


cg19741167
chr2:86263270
SCLC-I
POLR1A.GENEBODY
R


cg16769791
chr8:85178030
SCLC-I
RALYL.UTR5
R


cg00448761
chr19:6066102
SCLC-I
RFX2.UTR5
R


cg04303901
chr12:97886312
SCLC-I
RMST.GENEBODY
F


cg13077545
chr17:41832873
SCLC-I
SOST.GENEBODY
R
chr17:41832717-41833195
Island


cg15559684
chr3:63428234
SCLC-I
SYNPR.GENEBODY
R


cg07035875
chr16:52557205
SCLC-I
TOX3.UTR5
R


cg19115272
chr6:30139538
SCLC-I
TRIM15.GENEBODY
F
chr6:30139718-30140263
N_Shore


cg06093379
chr17:44896080
SCLC-I
WNT3.UTR5
R
chr17:44895800-44897025
Island


cg19154027
chr11:101983027
SCLC-I
YAP1.GENEBODY
F
chr11:101980632-101982330
S_Shore


cg22073838
chr11:101982817
SCLC-I
YAP1.TSS1500
F
chr11:101980632-101982330
S_Shore


cg20505457
chr14:69388953
SCLC-N
ACTN1.GENEBODY
F


cg04220881
chr7:152524814
SCLC-N
ACTR3B.GENEBODY
F


cg14755690
chr7:128868265
SCLC-N
AHCYL2.GENEBODY
R
chr7:128864320-128865655
S_Shelf


cg19798702
chr3:197247751
SCLC-N
BDH1.GENEBODY
R


cg03920522
chr7:94047477
SCLC-N
COL1A2.GENEBODY
R


cg12187160
chr1:9933026
SCLC-N
CTNNBIP1.UTR5
R


cg02531277
chr7:101558597
SCLC-N
CUX1.GENEBODY
R
chr7:101559402-101559625
N_Shore


cg18780243
chr13:32487268
SCLC-N
EEF1DP3.GENEBODY
R


cg19028997
chr1:205603040
SCLC-N
ELK4.TSS1500
R
chr1:205600493-205601432
S_Shore


cg02314596
chr14:89852725
SCLC-N
FOXN3.GENEBODY
R


cg16498113
chr12:42518821
SCLC-N
GXYLT1.GENEBODY
F


cg19513004
chr6:34206683
SCLC-N
HMGA1.UTR5
F
chr6:34202567-34206193
S_Shore


cg17401435
chr11:63887426
SCLC-N
MACROD1.GENEBODY
F
chr11:63887355-63887600
Island


cg25043538
chr11:63887437
SCLC-N
MACROD1.GENEBODY
R
chr11:63887355-63887600
Island


cg00648184
chr17:60828157
SCLC-N
MARCH10.GENEBODY
R


cg10414350
chr8:10210282
SCLC-N
MSRA.GENEBODY
R


cg09309024
chr16:29837267
SCLC-N
MVP.UTR5
F


cg06440275
chr8:2005701
SCLC-N
MYOM2.GENEBODY
R
chr8:2003809-2004059
S_Shore


cg01431993
chr2:182542864
SCLC-N
NEUROD1.GENEBODY
R


cg11528849
chr2:182542901
SCLC-N
NEUROD1.GENEBODY
R


cg16640855
chr2:182543233
SCLC-N
NEUROD1.GENEBODY
R


cg00369376
chr2:182542510
SCLC-N
NEUROD1.UTR3
F


cg02836529
chr2:182544413
SCLC-N
NEUROD1.UTR5
R
chr2:182547873-182549177
N_Shelf


cg20806345
chr2:182543706
SCLC-N
NEUROD1.UTR5
F


cg22976218
chr2:182544321
SCLC-N
NEUROD1.UTR5
R
chr2:182547873-182549177
N_Shelf


cg13538006
chr9:95897313
SCLC-N
NINJ1.TSS1500
R
chr9:95896007-95897016
S_Shore


cg11887270
chr3:52503232
SCLC-N
NISCH.GENEBODY
F


cg23731742
chr1:879958
SCLC-N
NOC2L.UTR3
R
chr1:875730-878363
S_Shore


cg02622825
chr20:34474890
SCLC-N
PHF20.GENEBODY
F


cg00284708
chr8:43147581
SCLC-N
POTEA.TSS200
F


cg05234415
chr19:38743744
SCLC-N
PPP1R14A.GENEBODY
R
chr19:38746638-38747379
N_Shelf


cg24657047
chr15:77317370
SCLC-N
PSTPIP1.GENEBODY
R
chr15:77320150-77320456
N_Shelf


cg23994112
chr17:75373457
SCLC-N
SEPT9.UTR5
R
chr17:75368688-75370506
S_Shelf


cg08399017
chr15:65934564
SCLC-N
SLC24A1.TSS1500
R


cg14647703
chr15:65934619
SCLC-N
SLC24A1.TSS1500
R


cg13969327
chr7:127526253
SCLC-N
SND1.GENEBODY
F


cg05214130
chr12:123945990
SCLC-N
SNRNP35.GENEBODY
F
chr12:123942639-123943001
S_Shelf


cg08573199
chr1:54739682
SCLC-N
SSBP3.GENEBODY
R


cg09621610
chr17:28074897
SCLC-N
SSH2.GENEBODY
F


cg13417891
chr17:35836996
SCLC-N
TADA2A.GENEBODY
F


cg02902261
chr7:72991150
SCLC-N
TBL2.GENEBODY
R
chr7:72992434-72993397
N_Shore


cg00678971
chr20:42667505
SCLC-N
TOX2.GENEBODY
F


cg02243624
chr17:66443040
SCLC-N
WIPI1.GENEBODY
R


cg13808641
chr9:96006533
SCLC-N
WNK2.GENEBODY
R
chr9:96009844-96010101
N_Shelf


cg15076368
chr3:39224943
SCLC-N
XIRP1.UTR3
R
chr3:39222280-39222670
S_Shelf


cg11964216
chr8:144521570
SCLC-N
ZC3H3.GENEBODY
R
chr8:144521358-144521608
Island


cg27232389
chr12:125555734
SCLC-P
AACS.GENEBODY
R


cg03020852
chr7:36446097
SCLC-P
ANLN.GENEBODY
F


cg11691710
chr7:36445998
SCLC-P
ANLN.GENEBODY
R


cg14197123
chr7:36446141
SCLC-P
ANLN.GENEBODY
R


cg17885507
chr7:36445877
SCLC-P
ANLN.GENEBODY
F


cg03517570
chr5:150490911
SCLC-P
ANXA6.GENEBODY
R


cg13297671
chr12:46169924
SCLC-P
ARID2.GENEBODY
F


cg18795320
chr12:14557493
SCLC-P
ATF7IP.UTR5
F


cg03075214
chr11:64867914
SCLC-P
C11orf2.GENEBODY
R
chr11:64863698-64863980
S_Shelf


cg06832246
chr11:93224210
SCLC-P
C11orf75.UTR5
R


cg05683632
chr19:41253983
SCLC-P
C19orf54.GENEBODY
F
chr19:41256317-41257234
N_Shelf


cg00704369
chr7:81996559
SCLC-P
CACNA2D1.GENEBODY
R


cg22171098
chr11:10421566
SCLC-P
CAND1.11.GENEBODY
F


cg09934399
chr19:13858064
SCLC-P
CCDC130.TSS1500
R
chr19:13858446-13858904
N_Shore


cg02817764
chr12:97104034
SCLC-P
CFAP54.GENEBODY
F


cg24677222
chr3:140102647
SCLC-P
CLSTN2.GENEBODY
F


cg16770048
chr22:19201167
SCLC-P
CLTCL1.GENEBODY
R


cg14701925
chr3:128980811
SCLC-P
COPG.GENEBODY
F


cg04182076
chr1:36937561
SCLC-P
CSF3R.GENEBODY
R


cg18969798
chr4:151157003
SCLC-P
DCLK2.GENEBODY
R


cg03803789
chr11:111854003
SCLC-P
DIXDC1.GENEBODY
R


cg13240089
chr3:196902029
SCLC-P
DLG1.GENEBODY
R


cg17758792
chr21:37620038
SCLC-P
DOPEY2.GENEBODY
F
chr21:37617467-37617872
S_Shelf


cg06923861
chr11:117355376
SCLC-P
DSCAML1.GENEBODY
F
chr11:117352691-117352961
S_Shelf


cg07956003
chr7:95433460
SCLC-P
DYNC1I1.UTR5
F


cg08275278
chr7:95433492
SCLC-P
DYNC1I1.UTR5
F


cg04983681
chr2:62952311
SCLC-P
EHBP1.GENEBODY
R


cg17728697
chr4:153434302
SCLC-P
FBXW7.UTR5
F


cg09472222
chr1:59980198
SCLC-P
FGGY.TSS1500
R


cg02220284
chr3:71013485
SCLC-P
FOXP1.GENEBODY
F


cg05366160
chr6:33039481
SCLC-P
HLA-DPA1.GENEBODY
F


cg13705753
chr6:33091912
SCLC-P
HLA-DPB2.GENEBODY
R


cg06839854
chr2:10536115
SCLC-P
HPCAL1.UTR5
R


cg02675973
chr8:73798545
SCLC-P
KCNB2.GENEBODY
R


cg05395645
chr3:197413859
SCLC-P
KIAA0226.GENEBODY
F


cg25601286
chr2:169408033
SCLC-P
LASS6.GENEBODY
R


cg11701604
chr11:36095771
SCLC-P
LDLRAD3.GENEBODY
F


cg07825782
chr1:117021479
SCLC-P
LOC101929023.TSS200
R


cg00600617
chr6:107221887
SCLC-P
LOC553137.GENEBODY
F


cg16054907
chr22:50706065
SCLC-P
MAPK11.GENEBODY
R
chr22:50705406-50706553
Island


cg01489441
chr16:1764111
SCLC-P
MAPK8IP3.GENEBODY
R


cg15564226
chr16:1764329
SCLC-P
MAPK8IP3.GENEBODY
R


cg10026427
chr1:156461666
SCLC-P
MEF2D.TSS1500
F


cg01149239
chr3:196746085
SCLC-P
MFI2.UTR3
F


cg04479757
chr22:26951319
SCLC-P
MIR548J.TSS200
R


cg11019743
chr6:168267395
SCLC-P
MLLT4.GENEBODY
F


cg13207778
chrX:149903801
SCLC-P
MTMR1.GENEBODY
R


cg25296465
chr3:195446826
SCLC-P
MUC20.TSS1500
R


cg03387092
chr3:123493248
SCLC-P
MYLK.GENEBODY
R


cg14175330
chr9:138949384
SCLC-P
NACC2.UTR5
R


cg05999426
chr20:46203476
SCLC-P
NCOA3.UTR5
F


cg19011089
chr20:33307672
SCLC-P
NCOA6.GENEBODY
R


cg14313328
chr1:54301402
SCLC-P
NDC1.GENEBODY
R
chr1:54303758-54304262
N_Shelf


cg18529415
chr1:41174259
SCLC-P
NFYC.TSS1500
R


cg04563108
chr18:56715086
SCLC-P
OACYLP.GENEBODY
R


cg25874150
chr10:34941561
SCLC-P
PARD3.GENEBODY
R


cg16318349
chr1:154917307
SCLC-P
PBXIP1.UTR3
R


cg13081156
chr5:134280996
SCLC-P
PCBD2.GENEBODY
F


cg14088354
chr1:233275911
SCLC-P
PCNXL2.GENEBODY
R


cg03264729
chr11:72347339
SCLC-P
PDE2A.GENEBODY
R


cg01580044
chr1:114300656
SCLC-P
PHTF1.GENEBODY
R
chr1:114301514-114302272
N_Shore


cg07313835
chr1:167342724
SCLC-P
POU2F1.GENEBODY
F


cg11597418
chr11:120165937
SCLC-P
POU2F3.GENEBODY
F


cg26855672
chr11:120113086
SCLC-P
POU2F3.GENEBODY
R
chr11:120110497-120110719
S_Shelf


cg03356778
chr11:120110544
SCLC-P
POU2F3.TSS1500
F
chr11:120110497-120110719
Island


cg05216984
chr2:242109132
SCLC-P
PPP1R7.GENEBODY
R


cg02593168
chr2:231931446
SCLC-P
PSMD1.GENEBODY
F


cg20314331
chr2:131129567
SCLC-P
PTPN18.GENEBODY
R
chr2:131129718-131130511
N_Shore


cg26797073
chr2:131129811
SCLC-P
PTPN18.GENEBODY
F
chr2:131129718-131130511
Island


cg15873449
chr18:12885569
SCLC-P
PTPN2.TSS1500
F
chr18:12883285-12884578
S_Shore


cg18983310
chr5:86603732
SCLC-P
RASA1.GENEBODY
F


cg08265811
chr2:178975718
SCLC-P
RBM45.TSS1500
R
chr2:178977078-178977828
N_Shore


cg22340762
chr1:183823538
SCLC-P
RGL1.GENEBODY
F


cg00618183
chr17:75143600
SCLC-P
SEC14L1.GENEBODY
R


cg12452539
chr3:150325281
SCLC-P
SELT.GENEBODY
F
chr3:150321002-150321791
S_Shelf


cg15786168
chr1:151117254
SCLC-P
SEMA6C.UTR5
F
chr1:151118049-151119373
N_Shore


cg06669752
chr5:138534431
SCLC-P
SIL1.TSS1500
R
chr5:138533870-138534113
S_Shore


cg24136932
chr8:22281979
SCLC-P
SLC39A14.GENEBODY
R


cg24272324
chr18:48603733
SCLC-P
SMAD4.GENEBODY
R


cg04619304
chr12:24434537
SCLC-P
SOX5.UTR5
R


cg01772824
chr17:28041399
SCLC-P
SSH2.GENEBODY
R


cg13921012
chr1:85119175
SCLC-P
SSX2IP.GENEBODY
F


cg06542565
chr9:126000925
SCLC-P
STRBP.GENEBODY
R


cg10288437
chr6:158432894
SCLC-P
SYNJ2.GENEBODY
F


cg10609655
chr20:60615080
SCLC-P
TAF4.GENEBODY
R


cg07262682
chr7:150494758
SCLC-P
TMEM176B.UTR5
R
chr7:150496809-150498206
N_Shelf


cg21289124
chr22:26951249
SCLC-P
TPST2.UTR5
R


cg07325342
chr16:3728204
SCLC-P
TRAP1.GENEBODY
F
chr16:3724344-3724849
S_Shelf


cg14211075
chr9:135818481
SCLC-P
TSC1.UTR5
R
chr9:135819526-135820529
N_Shore


cg00719067
chr13:27687798
SCLC-P
USP12.GENEBODY
R


cg05554594
chr17:80584498
SCLC-P
WDR45L.GENEBODY
F


cg08368885
chr9:129596150
SCLC-P
ZBTB43.GENEBODY
F
chr9:129595357-129595584
S_Shore


cg21876001
chr19:11594640
SCLC-P
ZNF653.GENEBODY
R
chr19:11594372-11594987
Island
















TABLE 7







Methylation markers for classification of SCLC-A using liquid biopsy

















Relation to


Methylation Site
Position (GRCh 37)
Gene
Strand
CpG Island Name
CpG Island





cg00799539
chr12: 103353183
ASCL1.UTR3
R
chr12: 103351579-
S_Shore






103352695


cg04610718
chr12: 103353362
ASCL1.UTR3
F
chr12: 103351579-
S_Shore






103352695


cg10672201
chr12: 103353320
ASCL1.UTR3
F
chr12: 103351579-
S_Shore






103352695


cg17277939
chr12: 70093008
BEST3.EXON1
F


cg11201256
chr1: 184403226
C1orf21.UTR5
R


cg07639982
chr10: 12555079
CAMK1D.GENEBODY
F


cg01566028
chr9: 123341267
CDK5RAP2.GENEBODY
R
chr9: 123342126-
N_Shore






123342513


cg06043710
chr10: 560371
DIP2C.GENEBODY
F


cg01154505
chr2: 112940409
FBLN7.GENEBODY
F
chr2: 112939287-
S_Shore






112939563


cg09643186
chr14: 65409452
GPX2.EXON1
F


cg03817675
chr7: 139299053
HIPK2.GENEBODY
R


cg00090674
chr22: 50446678
IL17REL.UTR5
F
chr22: 50448567-
N_Shore






50449521


cg02639667
chr5: 154092321
LARP1.TSS200
F


cg22053861
chr11: 65318683
LTBP3.GENEBODY
R
chr11: 65321225-
N_Shelf






65321823


cg14338051
chr20: 35924146
MANBAL.UTR5
F


cg00794178
chr3: 182897283
MCF2L2.GENEBODY
F
chr3: 182896920-
Island






182897381


cg16860004
chr8: 103137229
NCALD.TSS1500
F
chr8: 103135914-
S_Shore






103136775


cg04317756
chr22: 38085445
NOL12.GENEBODY
R
chr22: 38082302-
S_Shelf






38082796


cg01942646
chr1: 27240694
NROB2.TSS200
R


cg11249931
chr18: 21796096
OSBPL1A.GENEBODY
R


cg08279731
chr1: 144988231
PDE4DIP.GENEBODY
F


cg05161074
chr15: 42289885
PLA2G4E.GENEBODY
F


cg00773370
chr12: 6483772
SCNN1A.GENEBODY
R


cg07444408
chr4: 141218466
SCOC.UTR5
F


cg08758185
chr5: 150849936
SLC36A1.GENEBODY
F


cg27119612
chr15: 57491001
TCF12.GENEBODY
R


cg22904437
chr8: 81064304
TPD52.GENEBODY
R


cg04506569
chr2: 234837977
TRPM8.GENEBODY
F


cg04877165
chr2: 174096031
ZAK.GENEBODY
R


cg01610165
chr5: 124071029
ZNF608.GENEBODY
R
















TABLE 8







Methylation markers for classification of SCLC-N using liquid biopsy

















Relation to


Methylation Site
Position (GRCh 37)
Gene
Strand
CpG Island Name
CpG Island





cg20505457
chr14: 69388953
ACTN1.GENEBODY
F




cg04220881
chr7: 152524814
ACTR3B.GENEBODY
F


cg14755690
chr7: 128868265
AHCYL2.GENEBODY
R
chr7: 128864320-
S_Shelf






128865655


cg19798702
chr3: 197247751
BDH1.GENEBODY
R


cg03920522
chr7: 94047477
COL1A2.GENEBODY
R


cg12187160
chr1: 9933026
CTNNBIP1.UTR5
R


cg02531277
chr7: 101558597
CUX1.GENEBODY
R
chr7: 101559402-
N_Shore






101559625


cg18780243
chr13: 32487268
EEF1DP3.GENEBODY
R


cg19028997
chr1: 205603040
ELK4.TSS1500
R
chr1: 205600493-
S_Shore






205601432


cg02314596
chr14: 89852725
FOXN3.GENEBODY
R


cg16498113
chr12: 42518821
GXYLT1.GENEBODY
F


cg19513004
chr6: 34206683
HMGA1.UTR5
F
chr6: 34202567-
S_Shore






34206193


cg17401435
chr11: 63887426
MACROD1.GENEBODY
F
chr11: 63887355-
Island






63887600


cg25043538
chr11: 63887437
MACROD1.GENEBODY
R
chr11: 63887355-
Island






63887600


cg00648184
chr17: 60828157
MARCH10.GENEBODY
R


cg10414350
chr8: 10210282
MSRA.GENEBODY
R


cg09309024
chr16: 29837267
MVP.UTR5
F


cg06440275
chr8: 2005701
MYOM2.GENEBODY
R
chr8: 2003809-
S_Shore






2004059


cg01431993
chr2: 182542864
NEUROD1.GENEBODY
R


cg11528849
chr2: 182542901
NEUROD1.GENEBODY
R


cg16640855
chr2: 182543233
NEUROD1.GENEBODY
R


cg00369376
chr2: 182542510
NEUROD1.UTR3
F


cg02836529
chr2: 182544413
NEUROD1.UTR5
R
chr2: 182547873-
N_Shelf






182549177


cg20806345
chr2: 182543706
NEUROD1.UTR5
F


cg22976218
chr2: 182544321
NEUROD1.UTR5
R
chr2: 182547873-
N_Shelf






182549177


cg13538006
chr9: 95897313
NINJ1.TSS1500
R
chr9: 95896007-
S_Shore






95897016


cg11887270
chr3: 52503232
NISCH.GENEBODY
F


cg23731742
chr1: 879958
NOC2L.UTR3
R
chr1: 875730-
S_Shore






878363


cg02622825
chr20: 34474890
PHF20.GENEBODY
F


cg00284708
chr8: 43147581
POTEA.TSS200
F


cg05234415
chr19: 38743744
PPP1R14A.GENEBODY
R
chr19: 38746638-
N_Shelf






38747379


cg24657047
chr15: 77317370
PSTPIP1.GENEBODY
R
chr15: 77320150-
N_Shelf






77320456


cg23994112
chr17: 75373457
SEPT9.UTR5
R
chr17: 75368688-
S_Shelf






75370506


cg08399017
chr15: 65934564
SLC24A1.TSS1500
R


cg14647703
chr15: 65934619
SLC24A1.TSS1500
R


cg13969327
chr7: 127526253
SND1.GENEBODY
F


cg05214130
chr12: 123945990
SNRNP35.GENEBODY
F
chr12: 123942639-
S_Shelf






123943001


cg08573199
chr1: 54739682
SSBP3.GENEBODY
R


cg09621610
chr17: 28074897
SSH2.GENEBODY
F


cg13417891
chr17: 35836996
TADA2A.GENEBODY
F


cg02902261
chr7: 72991150
TBL2.GENEBODY
R
chr7: 72992434-
N_Shore






72993397


cg00678971
chr20: 42667505
TOX2.GENEBODY
F


cg02243624
chr17: 66443040
WIPI1.GENEBODY
R


cg13808641
chr9: 96006533
WNK2.GENEBODY
R
chr9: 96009844-
N_Shelf






96010101


cg15076368
chr3: 39224943
XIRP1.UTR3
R
chr3: 39222280-
S_Shelf






39222670


cg11964216
chr8: 144521570
ZC3H3.GENEBODY
R
chr8: 144521358-
Island






144521608
















TABLE 9







Methylation markers for classification of SCLC-P using liquid biopsy

















Relation to


Methylation Site
Position (GRCh 37)
Gene
Strand
CpG Island Name
CpG Island





cg27232389
chr12: 125555734
AACS.GENEBODY
R




cg03020852
chr7: 36446097
ANLN.GENEBODY
F


cg11691710
chr7: 36445998
ANLN.GENEBODY
R


cg14197123
chr7: 36446141
ANLN.GENEBODY
R


cg17885507
chr7: 36445877
ANLN.GENEBODY
F


cg03517570
chr5: 150490911
ANXA6.GENEBODY
R


cg13297671
chr12: 46169924
ARID2.GENEBODY
F


cg18795320
chr12: 14557493
ATF7IP.UTR5
F


cg03075214
chr11: 64867914
C11orf2.GENEBODY
R
chr11: 64863698-
S_Shelf






64863980


cg06832246
chr11: 93224210
C11orf75.UTR5
R


cg05683632
chr19: 41253983
C19orf54.GENEBODY
F
chr19: 41256317-
N_Shelf






41257234


cg00704369
chr7: 81996559
CACNA2D1.GENEBODY
R


cg22171098
chr11: 10421566
CAND1.11.GENEBODY
F


cg09934399
chr19: 13858064
CCDC130.TSS1500
R
chr19: 13858446-
N_Shore






13858904


cg02817764
chr12: 97104034
CFAP54.GENEBODY
F


cg24677222
chr3: 140102647
CLSTN2.GENEBODY
F


cg16770048
chr22: 19201167
CLTCL1.GENEBODY
R


cg14701925
chr3: 128980811
COPG.GENEBODY
F


cg04182076
chr1: 36937561
CSF3R.GENEBODY
R


cg18969798
chr4: 151157003
DCLK2.GENEBODY
R


cg03803789
chr11: 111854003
DIXDC1.GENEBODY
R


cg13240089
chr3: 196902029
DLG1.GENEBODY
R


cg17758792
chr21: 37620038
DOPEY2.GENEBODY
F
chr21: 37617467-
S Shelf






37617872


cg06923861
chr11: 117355376
DSCAML1.GENEBODY
F
chr11: 117352691-
S_Shelf






117352961


cg07956003
chr7: 95433460
DYNC111.UTR5
F


cg08275278
chr7: 95433492
DYNC111.UTR5
F


cg04983681
chr2: 62952311
EHBP1.GENEBODY
R


cg17728697
chr4: 153434302
FBXW7.UTR5
F


cg09472222
chr1: 59980198
FGGY.TSS1500
R


cg02220284
chr3: 71013485
FOXP1.GENEBODY
F


cg05366160
chr6: 33039481
HLA-DPA1.GENEBODY
F


cg13705753
chr6: 33091912
HLA-DPB2.GENEBODY
R


cg06839854
chr2: 10536115
HPCAL1.UTR5
R


cg02675973
chr8: 73798545
KCNB2.GENEBODY
R


cg05395645
chr3: 197413859
KIAA0226.GENEBODY
F


cg25601286
chr2: 169408033
LASS6.GENEBODY
R


cg11701604
chr11: 36095771
LDLRAD3.GENEBODY
F


cg07825782
chr1: 117021479
LOC101929023.TSS200
R


cg00600617
chr6: 107221887
LOC553137.GENEBODY
F


cg16054907
chr22: 50706065
MAPK11.GENEBODY
R
chr22: 50705406-
Island






50706553


cg01489441
chr16: 1764111
MAPK8IP3.GENEBODY
R


cg15564226
chr16: 1764329
MAPK8IP3.GENEBODY
R


cg10026427
chr1: 156461666
MEF2D.TSS1500
F


cg01149239
chr3: 196746085
MFI2.UTR3
F


cg04479757
chr22: 26951319
MIR548J.TSS200
R


cg11019743
chr6: 168267395
MLLT4.GENEBODY
F


cg13207778
chrX: 149903801
MTMR1.GENEBODY
R


cg25296465
chr3: 195446826
MUC20.TSS1500
R


cg03387092
chr3: 123493248
MYLK.GENEBODY
R


cg14175330
chr9: 138949384
NACC2.UTR5
R


cg05999426
chr20: 46203476
NCOA3.UTR5
F


cg19011089
chr20: 33307672
NCOA6.GENEBODY
R


cg14313328
chr1: 54301402
NDC1.GENEBODY
R
chr1: 54303758-
N Shelf






54304262


cg18529415
chr1: 41174259
NFYC.TSS1500
R


cg04563108
chr18: 56715086
OACYLP.GENEBODY
R


cg25874150
chr10: 34941561
PARD3.GENEBODY
R


cg16318349
chr1: 154917307
PBXIP1.UTR3
R


cg13081156
chr5: 134280996
PCBD2.GENEBODY
F


cg14088354
chr1: 233275911
PCNXL2.GENEBODY
R


cg03264729
chr11: 72347339
PDE2A.GENEBODY
R


cg01580044
chr1: 114300656
PHTF1.GENEBODY
R
chr1: 114301514-
N_Shore






114302272


cg07313835
chr1: 167342724
POU2F1.GENEBODY
F


cg11597418
chr11: 120165937
POU2F3.GENEBODY
F


cg26855672
chr11: 120113086
POU2F3.GENEBODY
R
chr11: 120110497-
S_Shelf






120110719


cg03356778
chr11: 120110544
POU2F3.TSS1500
F
chr11: 120110497-
Island






120110719


cg05216984
chr2: 242109132
PPP1R7.GENEBODY
R


cg02593168
chr2: 231931446
PSMD1.GENEBODY
F


cg20314331
chr2: 131129567
PTPN18.GENEBODY
R
chr2: 131129718-
N_Shore






131130511


cg26797073
chr2: 131129811
PTPN18.GENEBODY
F
chr2: 131129718-
Island






131130511


cg15873449
chr18: 12885569
PTPN2.TSS1500
F
chr18: 12883285-
S_Shore






12884578


cg18983310
chr5: 86603732
RASA1.GENEBODY
F


cg08265811
chr2: 178975718
RBM45.TSS1500
R
chr2: 178977078-
N_Shore






178977828


cg22340762
chr1: 183823538
RGL1.GENEBODY
F


cg00618183
chr17: 75143600
SEC14L1.GENEBODY
R


cg12452539
chr3: 150325281
SELT.GENEBODY
F
chr3: 150321002-
S_Shelf






150321791


cg15786168
chr1: 151117254
SEMA6C.UTR5
F
chr1: 151118049-
N_Shore






151119373


cg06669752
chr5: 138534431
SIL1.TSS1500
R
chr5: 138533870-
S_Shore






138534113


cg24136932
chr8: 22281979
SLC39A14.GENEBODY
R


cg24272324
chr18: 48603733
SMAD4.GENEBODY
R


cg04619304
chr12: 24434537
SOX5.UTR5
R


cg01772824
chr17: 28041399
SSH2.GENEBODY
R


cg13921012
chr1: 85119175
SSX2IP.GENEBODY
F


cg06542565
chr9: 126000925
STRBP.GENEBODY
R


cg10288437
chr6: 158432894
SYNJ2.GENEBODY
F


cg10609655
chr20: 60615080
TAF4.GENEBODY
R


cg07262682
chr7: 150494758
TMEM176B.UTR5
R
chr7: 150496809-
N_Shelf






150498206


cg21289124
chr22: 26951249
TPST2.UTR5
R


cg07325342
chr16: 3728204
TRAP1.GENEBODY
F
chr16: 3724344-
S_Shelf






3724849


cg14211075
chr9: 135818481
TSC1.UTR5
R
chr9: 135819526-
N_Shore






135820529


cg00719067
chr13: 27687798
USP12.GENEBODY
R


cg05554594
chr17: 80584498
WDR45L.GENEBODY
F


cg08368885
chr9: 129596150
ZBTB43.GENEBODY
F
chr9: 129595357-
S_Shore






129595584


cg21876001
chr19: 11594640
ZNF653.GENEBODY
R
chr19: 11594372-
Island






11594987
















TABLE 10







Methylation markers for classification of SCLC-I using liquid biopsy

















Relation to


Methylation Site
Position (GRCh 37)
Gene
Strand
CpG Island Name
CpG Island





cg09248054
chr1: 969257
AGRN.GENEBODY
F
chr1: 967966-
Island






970238


cg02379560
chr4: 40859280
APBB2.GENEBODY
F
chr4: 40858884-
S_Shore






40859162


cg04917391
chr4: 40859259
APBB2.GENEBODY
F
chr4: 40858884-
S_Shore






40859162


cg05020685
chr4: 40858965
APBB2.GENEBODY
F
chr4: 40858884-
Island






40859162


cg06485940
chr4: 40859293
APBB2.GENEBODY
F
chr4: 40858884-
S_Shore






40859162


cg16364495
chr4: 40859251
APBB2.GENEBODY
F
chr4: 40858884-
S_Shore






40859162


cg05857126
chr16: 52108007
C16orf97.TSS200
F


cg13780782
chr16: 52107988
C16orf97.TSS200
F


cg02008691
chr16: 52589450
CASC16.GENEBODY
F


cg24664798
chr16: 52640476
CASC16.GENEBODY
R


cg17265693
chr17: 7166490
CLDN7.TSS1500
F
chr17: 7164285-
S_Shore






7166245


cg06508056
chr7: 146594213
CNTNAP2.GENEBODY
R


cg15932065
chr7: 146470241
CNTNAP2.GENEBODY
F


cg16405211
chr7: 146897691
CNTNAP2.GENEBODY
R


cg18804920
chr7: 146572638
CNTNAP2.GENEBODY
R


cg23889772
chr19: 10077324
COL5A3.GENEBODY
F
chr19: 10077031-
Island






10077444


cg07270851
chr11: 65779332
CST6.TSS200
F
chr11: 65779311-
Island






65779767


cg24238564
chr11: 65779343
CST6.TSS200
F
chr11: 65779311-
Island






65779767


cg03850035
chr2: 222367110
EPHA4.GENEBODY
R


cg02659920
chr11: 726335
EPS8L2.GENEBODY
F
chr11: 725596-
Island






726870


cg05651265
chr11: 726367
EPS8L2.GENEBODY
R
chr11: 725596-
Island






726870


cg10976861
chr2: 239149937
HES6.TSS1500
F
chr2: 239147592-
S_Shore






239149900


cg24127874
chr2: 239149859
HES6.TSS1500
F
chr2: 239147592-
Island






239149900


cg02365303
chr5: 147052498
JAKMIP2.UTR5
F


cg11799006
chr5: 147101975
JAKMIP2.UTR5
R


cg00336977
chr8: 73826000
KCNB2.GENEBODY
R


cg02125259
chr8: 73559340
KCNB2.GENEBODY
R


cg09433131
chr8: 73480179
KCNB2.GENEBODY
F


cg14865862
chr8: 73632304
KCNB2.GENEBODY
R


cg20136513
chr8: 73711260
KCNB2.GENEBODY
F


cg00378510
chr19: 2291020
LINGO3.GENEBODY
F
chr19: 2289895-
Island






2291904


cg06473097
chr8: 73643063
LOC101926908.TSS1500
R


cg23844705
chr1: 164573835
PBX1.GENEBODY
R


cg19741167
chr2: 86263270
POLR1A.GENEBODY
R


cg16769791
chr8: 85178030
RALYL.UTR5
R


cg00448761
chr19: 6066102
RFX2.UTR5
R


cg04303901
chr12: 97886312
RMST.GENEBODY
F


cg13077545
chr17: 41832873
SOST.GENEBODY
R
chr17: 41832717-
Island






41833195


cg15559684
chr3: 63428234
SYNPR.GENEBODY
R


cg07035875
chr16: 52557205
TOX3.UTR5
R


cg19115272
chr6: 30139538
TRIM15.GENEBODY
F
chr6: 30139718-
N_Shore






30140263


cg06093379
chr17: 44896080
WNT3.UTR5
R
chr17: 44895800-
Island






44897025


cg19154027
chr11: 101983027
YAP1.GENEBODY
F
chr11: 101980632-
S_Shore






101982330


cg22073838
chr11: 101982817
YAP1.TSS1500
F
chr11: 101980632-
S_Shore






101982330
















TABLE 11







Top 10 Combinations of two genes for the differentiation of SCLC-A











Methylation
Position
LogReg
RF



Sites
(GRCh 37)
(Mean AUC)1
(MeanAUC)2
Name














cg17542751_cg26319503
chr22: 44568725_chr1:
1.0000000
0.8930833
PARVG.TSS200_GRIK3.GENEBODY



37313328


cg08581399_cg00512287
chr8: 110305656_chr11:
0.9918611
NA
NUDCD1.GENEBODY_PHLDB1.GENEBODY



118512372


cg02290110_cg25353896
chr19: 461808_chr22:
0.9917222
NA
SHC2.TSS1500_PARVG.TSS200



44568753


cg13429423_cg26319503
chr22: 44568775_chr1:
0.9898889
0.9830000
PARVG.TSS200_GRIK3.GENEBODY



37313328


cg14503873_cg05930278
chr9: 117036748_chr3:
0.9883889
0.9866667
COL27A1.GENEBODY_SH3BP5.GENEBODY



15362399


cg00512287_cg16777369
chr11: 118512372_chr10:
0.9877500
0.9844444
PHLDB1.GENEBODY_TCERG1L.GENEBODY



132900674


cg17542751_cg26148923
chr22: 44568725_chr3:
0.9866944
NA
PARVG.TSS200_LINC00578.GENEBODY



177310535


cg14503873_cg25694807
chr9: 117036748_chr2:
0.9855833
0.9869167
COL27A1.GENEBODY_RBMS1.GENEBODY



161329607


cg13703062_cg25433259
chr18: 32924349_chr6:
0.9858056
NA
ZNF24.EXON1_OSTCP1.GENEBODY



159271784


cg15892280_cg26319503
chr21: 40180000_chr1:
0.9853056
NA
ETS2.UTR5_GRIK3.GENEBODY



37313328






1Mean area under the curve as determined by the logistic regression model (LogReg).



2Mean area under the curve as determined by the random forrest model (RF).













TABLE 12







Top 10 Combinations of two genes for the differentiation of SCLC-N











Methylation
Position
LogReg
RF



Sites
(GRCh 37)
(Mean AUC)1
(Mean AUC)2
Name














cg10468340_cg05202032
chr3: 58318421_chr17:
1.0000000
0.9963333
PXK.TSS200_VPS53.GENEBODY



424205


cg10468340_cg05328630
chr3: 58318421_chr13:
1.0000000
1.0000000
PXK.TSS200_CLYBL.GENEBODY



100506703


cg05328630_cg05212450
chr13: 100506703_chr7:
0.9900000
NA
CLYBL.GENEBODY MAD1L1.GENEBODY



2149814


cg17589175_cg23045716
chr11: 64085337_chr4:
0.9890000
NA
PRDXS.TSS1500_LOC100130872.GENEBODY



1201881


cg22557350_cg25870970
chr10: 126432983_chr20:
0.9871481
NA
FAMS3B.TSS200_ATPSA.GENEBODY



50294927


cg15193475_cg02243624
chr15: 80998711_chr17:
0.9870000
NA
FAM108C1.GENEBODY_WIPI1.GENEBODY



66443040


cg22976218_cg19028997
chr2: 182544321_chr1:
0.8869259
0.9814444
NEUROD1.UTR5_ELK4.TSS1500



205603040


cg14647703_cg23516715
chr15: 65934619_chrX:
0.9858889
0.9833333
SLC24A1.TSS1500_EDA.GENEBODY



68890853


cg27088449_cg10414350
chr22: 21272634_chr8:
0.9866667
NA
CRKL.GENEBODY_MSRA.GENEBODY



10210282


cg01789478_cg08399017
chr2: 182545485_chr15:
0.9865556
NA
NEUROD1.TSS200_SLC24A1.TSS1500



65934564






1Mean area under the curve as determined by the logistic regression model (LogReg).



2Mean area under the curve as determined by the random forrest model (RF).






Example 2—Identification of Specific Markers for SCLC

Using the same methods described in Example 1, 27 markers were identified that are useful for classifying SCLC specifically vs. other types of cancers, and that are sufficiently differentially methylated to be included in a liquid biopsy assay. The list of markers is provided in Table 13. To get better specificities, only lung SCLC, lung Adenocarcinoma and lung Squamous cell carcinoma cell lines were included in the marker selection process.


To make sure that the markers were not only effective for analysis of SCLC cell lines, methylation levels were analyzed using the GSE60644 dataset, comprising 124 lung cancers from various histologies (FIG. 11). Importantly, the markers derived from the cell lines were indeed also capable of uniquely distinguishing SCLC in analysis of tissue samples.


Finally, to analyze possible overlap with other tumor entities, the markers were also analyzed on the pan-cancer TCGA set (FIG. 12). Interestingly, overlap was mainly seen in samples form neurological cancers. Given the neuroendocrine phenotype of SCLC and other HGNEC this result is quite expected. However, for some markers an overlap can also be seen in skin cancer samples.


In summary, the markers worked well for the selection of SCLC and other HGNEC, especially against other lung cancer entities.









TABLE 13







Markers for distinguishing SCLC from other cancer types

















Relation to


Methylation Site
Position (GRCh 37)
Gene
Strand
CpG Island Name
CpG Island





cg09052983
chr18: 52495605
RAB27B.TSS1500
R
chr18: 52495604-
Island






52496007


cg03196720
chr12: 6473299
SCNN1A.GENEBODY
F
chr12: 6472660-
Island






6473322


cg03851835
chr11: 107711742
SLC35F2.GENEBODY
R


cg23847017
chr1: 28764854
PHACTR4.EXON1
F


cg06029700
chr12: 6473311
SCNN1A.GENEBODY
F
chr12: 6472660-
Island






6473322


cg16955166
chr18: 52495633
RAB27B.TSS1500
R
chr18: 52495604-
Island






52496007


cg00956142
chr1: 28765031
PHACTR4.GENEBODY
F


cg07101841
chr17: 75315527
SEPT9.UTR5
F


cg22099241
chr6: 31379358
MICA.GENEBODY
R


cg00233633
chr7: 29153560
CPVL.GENEBODY
F


cg02339793
chr17: 79225573
SLC38A10.GENEBODY
R


cg07093324
chr2: 114652143
ACTR3.GENEBODY
R
chr2: 114647669-
S_Shelf






114648312


cg18166947
chr22: 18189443
BCL2L13.GENEBODY
R


cg21055554
chr12: 113652889
IQCD.UTR5
F


cg18474885
chr21: 46292084
PTTG1IP.GENEBODY
R
chr21: 46292709-
N_Shore






46294744


cg19166875
chr10: 95241944
MYOF.EXON1
R


cg24473500
chr7: 871436
UNC84A.UTR5
F


cg22234930
chr15: 72519739
PKM2.UTR5
F
chr15: 72522131-
N_Shelf






72524238


cg23715728
chr6: 31379258
MICA.GENEBODY
R


cg04650676
chr17: 75315486
SEPT9.UTR5
F


cg00134210
chr10: 14644132
FAM107B.GENEBODY
R
chr10: 14645752-
N_Shore






14646705


cg04387396
chr10: 72593165
SGPL1.GENEBODY
F


cg01807820
chr12: 6473007
SCNN1A.GENEBODY
R
chr12: 6472660-
Island






6473322


cg15689991
chr12: 65019329
RASSF3.GENEBODY
R


cg03577157
chr5: 80716263
RNUSE.GENEBODY
F


cg11708454
chr19: 38794664
YIF1B.UTR3
F


cg08962271
chr11: 67273496
PITPNM1.TSS1500
R
chr11: 67275067-
N_Shore






67276431









Example 3—Association of Drug Response with Methylation Markers

Association of methylation sites with response to treatment was assessed using the GDSC dataset that comprises ˜480,000 methylation sites with samples tested across 449 different drugs. IC50 value (as a measurement of sensitivity) was correlated with methylation level using Spearman correlation. The top 16 associations between methylation sites and drugs are highlighted in FIG. 13 and shown in in Table 14.















TABLE 14










Spearman



Methylation



Spearman
Adjusted


Site
Position (GRCh 37)
Gene
Drug Name
Correlation
p value
R2





















cg15358855
chr11:129830237
PRDM10.GENEBODY
QL-XII-61
−0.901750423
0.004869906
0.813154


cg06883206
chr4:152172102
.
HG-5-88-01
0.868577075
0.037497804
0.754426


cg02516288
chr1:155177783
MTX1.TSS1500
ZG-10
0.867588933
0.016753958
0.752711


cg18357526
chr6:26021779
HIST1H4A.TSS200
Elephantin
−0.857771261
0.000172795
0.735772


cg16557178
chr17:46804309
HOXB13.GENEBODY
BI-2536
0.822267206
6.65E−05
0.676123


cg16770832
chr14:56604516
PELI2.GENEBODY
Dinaciclib
0.814516129
0.006829969
0.663437


cg16557178
chr17:46804309
HOXB13.GENEBODY
GW843682X
0.812348178
0.000120916
0.65991


cg14644871
chr7:26192756
NFE2L3.GENEBODY
OTX015
0.805718475
0.012850952
0.649182


cg18166636
chr5:178956931
.
JAK_8517
−0.805351906
0.013184766
0.648592


cg03083695
chr9:130659142
ST6GALNAC6.GENEBODY
Sinularin
0.799486804
0.019731269
0.639179


cg11648522
chr1:15272238
KIAA1026.TSS200
Sunitinib
0.795546559
0.000593673
0.632894


cg02929982
chr14:63872285
PPP2R5E.GENEBODY
ULK1_4989
0.795454545
0.013889773
0.632748


cg05570682
chr8:42132866
IKBKB.GENEBODY
GSK591
0.795120321
0.015770449
0.632216


cg17800714
chrX:153656771
ATP6AP1.TSS1500
Fludarabine
−0.793327838
0.029713803
0.629369


cg22981158
chr19:47156401
DACT3.GENEBODY
JAK1_8709
0.788489736
0.040598825
0.621716


cg06476606
chr10:91061728
IFIT2.UTR5
IGF1R_3801
−0.785557185
0.030394645
0.6171









Example 4—Identification of Methylation Markers Associated with SCLC Subtypes Based on Reduced Representation Bisulfite Sequencing (RRBS) Analysis of Lung Cancer Cell Lines and Patient-Derived Xenograft Samples

Data was generated from 59 SCLC cell lines and 68 patient derived xenograft models. Reduced representation bisulfite sequencing (RRBS) was performed at the MD Anderson Cancer Center and approximately 1-2 million methylation sites were analyzed as already described in Example 1. Briefly, receiver-operator characteristics (ROC) was used to assess the association of each of the methylation sites with one of the subtypes. A higher area under the curve (AUC) indicated a stronger association of a methylation site with the subtype. For the SCLC-A and the SCLC-N subtype, the top 15,000 methylation sites based on their AUC were further evaluated using different machine learning approaches (logistic regression, support vector machines, random forest and gradient boosting) and feature selection was used to further select methylation sites that were of high importance in the respective models. For the SCLC-P and the SCLC-I subset, limited cell line data protracted the use of machine learning models, however, many methylation sites demonstrated an AUC of 1 indicating a perfect specificity of the sites for each of the subtypes and all the sites with AUC=1 were further evaluated. A graphical overview on the analysis scheme is given in FIG. 14. The full list of methylation sites were further evaluated for their suitability in a liquid biopsy assay, as described in Example 1. For the assessment of tissue-specific methylation as well as the methylation in cfDNA, data from the Encode project were used and retrieved under the GEO accession number GSE27584. cfDNA was retrieved from array express under the accession number E-MTAB-8858. Methylation sites that were considered suitable for a liquid biopsy assay are provided in Tables 15-18.


In an additional analysis, differentially methylated sites able to differentiate the SCLC-A and the SCLC-N subsets were retrieved from the xenograft models complementing the list already obtained from the cell line data. Only methylation sites with an AUC=1 were included and further validated for their suitability in a liquid biopsy assay. The selected methylation sites are provided in Table 19.


The methylation sites were validated by generating machine learning models as highlighted in the initial application. First, the methylation sites were validated on cell line data. As highlighted in FIG. 15, the selected methylation sites served to build a logistic regression models that were able to perfectly distinguish the different SCLC-Subtypes.


The inventors also validated the same logistic regression model on the xenograft samples as highlighted in FIG. 16. The classification was very good, with a very good separation of SCLC-A and SCLC-N. There was some overlap between the two subsets, however, SCLC-A and SCLC-N portions can be present in the same sample and the subtypes can change over time, thus it seems that the models also recapitulate this state. Importantly, while there was only one SCLC-P sample in the dataset, this was correctly classified. Consequently, the identified methylation sites do not only classify cell lines but also patient derived tumor tissue.


In summary, the methylation sites derived from RRBS showed comparable performance to the methylation sites derived from the microarray data and complement them by adding additional sites. The distribution of the methylation sites in the final selection of markers considered suitable for a liquid biopsy assay are highlighted in FIGS. 17A-17B (see also. All the methylation sites are evenly distributed across the chromosome.


Lastly, while the methylation in cell lines strongly correlates with the methylation in patient-derived samples, did an additional analysis was done based on the xenograft models to further enhance the classification of those two subtypes and to include additional methylation sites. In total, 26283 methylation sites with an AUC=1 were detected and were further validated. A special emphasis was put on selecting regions comprising multiple methylation sites as this may be more suitable for an assay that can span multiple methylation sites at once. The distribution of the newly selected sites is highlighted in FIGS. 18A-18B (see Table 19).









TABLE 15







Methylation sites associated with SCLC-A identified from RRBS suitable for a liquid biopsy assay









Methylation Site
GENE SYMBOL
Annotation





chr7: 73742662
ABHD11
Distal Intergenic


chr7: 31082303
ADCYAP1R1
Intron (ENST00000409363.5/117, intron 4 of 13)


chr16: 89359643
ANKRD11
Intron (ENST00000646166.1/29123, intron 3 of 4)


chr16: 89359653
ANKRD11
Intron (ENST00000646166.1/29123, intron 3 of 4)


chr19: 1083053
ARHGAP45
Promoter (<=1 kb)


chr17: 3959798
ATP2A3
Intron (ENST00000309890.11/489, intron 1 of 21)


chr10: 28936225
C10orf126
Intron (ENST00000646289.1/101929218, intron 7 of 7)


chr17: 81224031
CEP131
Promoter (1-2 kb)


chr17: 81223869
CEP131
Promoter (<=1 kb)


chr7: 73831674
CLDN4
Promoter (<=1 kb)


chr7: 139614241
CLEC2L
Intron (ENST00000406875.8/28996, intron 8 of 14)


chr16: 23403661
COG7
Intron (ENST00000307149.10/91949, intron 13 of 16)


chr17: 57874806
CUEDC1
Promoter (2-3 kb)


chr17: 57874798
CUEDC1
Promoter (2-3 kb)


chr17: 57874857
CUEDC1
Promoter (2-3 kb)


chr17: 57874856
CUEDC1
Promoter (2-3 kb)


chr17: 57874868
CUEDC1
Promoter (2-3 kb)


chr17: 57874728
CUEDC1
Promoter (2-3 kb)


chr17: 57874706
CUEDC1
Promoter (2-3 kb)


chr17: 57874660
CUEDC1
Promoter (1-2 kb)


chr2: 241762449
D2HGDH
Intron (ENST00000486953.5/728294, intron 3 of 3)


chr6: 168372036
DACT2
Distal Intergenic


chr3: 132554688
DNAJC13
Distal Intergenic


chr3: 132554514
DNAJC13
Distal Intergenic


chr2: 73324598
EGR4
Distal Intergenic


chr2: 47370087
EPCAM
Promoter (<=1 kb)


chr9: 134962684
FCN1
Distal Intergenic


chr11: 64082017
FLRT1
Exon (ENST00000544948.1/ENST00000544948.1, exon 1 of 3)


chr3: 172214285
FNDC3B
Intron (ENST00000415807.7/64778, intron 3 of 25)


chr17: 74961036
HID1
Promoter (<=1 kb)


chr17: 74961013
HID1
Promoter (<=1 kb)


chr2: 128299665
HS6ST1
Intron (ENST00000469019.1/9394, intron 1 of 2)


chr2: 98539557
INPP4A
Exon (ENST00000409016.8/3631, exon 10 of 26)


chr20: 20364993
INSM1
Exon (ENST00000623641.1/ENST00000623641.1, exon 1 of 1)


chr20: 3223598
ITPA
Promoter (1-2 kb)


chr20: 3223530
ITPA
Promoter (1-2 kb)


chr20: 3223525
ITPA
Promoter (1-2 kb)


chr2: 113974997
LINC01191
Intron (ENST00000663402.1/440900, intron 1 of 2)


chr21: 34743983
LINC01426
Promoter (1-2 kb)


chr20: 22678481
LINC01747
Intron (ENST00000634603.2/105372566, intron 2 of 2)


chr20: 22652808
LINC01747
Distal Intergenic


chr20: 22675604
LINC01747
Intron (ENST00000634603.2/105372566, intron 2 of 2)


chr11: 44963352
LINC02685
Distal Intergenic


chr7: 66664590
LOC100996437
Intron (ENST00000503687.2/27342, intron 3 of 12)


chr9: 103687100
LOC101928523
Distal Intergenic


chr2: 216985900
LOC105373876
Intron (ENST00000447289.1/ENST00000447289.1, intron 3 of 3)


chr2: 216986079
LOC105373876
Intron (ENST00000447289.1/ENST00000447289.1, intron 3 of 3)


chr16: 11391854
LOC400499
Promoter (<=1 kb)


chr11: 65551228
LTBP3
Promoter (<=1 kb)


chr11: 65551199
LTBP3
Promoter (<=1 kb)


chr7: 2123748
MAD1L1
Intron (ENST00000265854.11/8379, intron 9 of 16)


chr16: 84519935
MEAK7
Intron (ENST00000565079.5/57707, intron 1 of 3)


chr9: 93819287
MIR4291
Promoter (<=1 kb)


chr9: 93819136
MIR4291
Promoter (<=1 kb)


chr9: 93819135
MIR4291
Promoter (<=1 kb)


chr7: 157017814
MNX1-AS1
Distal Intergenic


chr17: 75910594
MRPL38
Promoter (<=1 kb)


chr5: 43604106
NNT
Promoter (<=1 kb)


chr1: 944700
NOC2L
Promoter (<=1 kb)


chr8: 22024463
NPM2
Promoter (<=1 kb)


chr1: 163692381
NUF2
Distal Intergenic


chr22: 44049781
PARVB
Intron (ENST00000406477.7/29780, intron 2 of 13)


chr19: 3656261
PIP5K1C
Intron (ENST00000335312.7/23396, intron 6 of 17)


chr19: 3656352
PIP5K1C
Intron (ENST00000335312.7/23396, intron 6 of 17)


chr19: 3656274
PIP5K1C
Intron (ENST00000335312.7/23396, intron 6 of 17)


chr3: 64225316
PRICKLE2
Promoter (<=1 kb)


chr9: 131721355
RAPGEF1
Intron (ENST00000372195.5/2889, intron 1 of 23)


chr9: 131721356
RAPGEF1
Intron (ENST00000372195.5/2889, intron 1 of 23)


chr12: 97321085
RMST
Distal Intergenic


chr10: 78139388
RPS24
Distal Intergenic


chr20: 46641000
SLC13A3
Intron (ENST00000372121.5/64849, intron 1 of 6)


chr1: 205965076
SLC26A9
Distal Intergenic


chr1: 205965024
SLC26A9
Distal Intergenic


chr6: 168440498
SMOC2
Promoter (<=1 kb)


chr17: 43755336
SOST
3′ UTR


chr3: 181315137
SOX2-OT
Intron (ENST00000643236.2/347689, intron 3 of 5)


chr1: 54356529
SSBP3
Promoter (<=1 kb)


chr1: 36366642
STK40
Promoter (<=1 kb)


chr1: 36366474
STK40
Promoter (<=1 kb)


chr12: 124088409
ZNF664
Exon (ENST00000621669.1/ENST00000621669.1, exon 1 of 1)


chr11: 60866977
ZP1
Promoter (<=1 kb)
















TABLE 16







Methylation sites associated with SCLC-N identified


from RRBS suitable for a liquid biopsy assay









Methylation Site
GENE SYMBOL
Annotation





chr16: 57620421
ADGRG1
Promoter (<=1 kb)


chr7: 105689129
ATXN7L1
Promoter (2-3 kb)


chr9: 134051444
BRD3
Promoter (1-2 kb)


chr17: 50604550
CACNA1G
Intron (ENST00000359106.10/8913, intron 22 of 37)


chr14: 24311062
CIDEB
Promoter (<=1 kb)


chr15: 68211219
CLN6
Promoter (1-2 kb)


chr17: 57874862
CUEDC1
Promoter (2-3 kb)


chr1: 28869236
EPB41
3′ UTR


chr5: 160245925
FABP6
Distal Intergenic


chr6: 154359428
IPCEF1
Promoter (2-3 kb)


chr15: 68347588
ITGA11
Intron (ENST00000315757.9/22801, intron 10 of 29)


chr15: 68347636
ITGA11
Intron (ENST00000315757.9/22801, intron 10 of 29)


chr7: 150975167
KCNH2
Promoter (2-3 kb)


chr19: 5035647
KDM4B
Intron (ENST00000611640.4/23030, intron 3 of 23)


chr16: 67178561
KIAA0895L
Promoter (<=1 kb)


chr16: 67178592
KIAA0895L
Promoter (<=1 kb)


chr16: 85287162
LINC00311
Intron (ENST00000637419.1/23199, intron 1 of 2)


chr7: 66664578
LOC100996437
Intron (ENST00000503687.2/27342, intron 3 of 12)


chr7: 66664596
LOC100996437
Intron (ENST00000503687.2/27342, intron 3 of 12)


chr7: 66664710
LOC100996437
Intron (ENST00000503687.2/27342, intron 3 of 12)


chr1: 53320090
LRP8
Intron (ENST00000306052.12/7804, intron 2 of 18)


chr1: 25771820
MAN1C1
Promoter (<=1 kb)


chr8: 144508436
MFSD3
Promoter (<=1 kb)


chr6: 33694527
MIR3934
Exon (ENST00000606961.1/ENST00000606961.1, exon 1 of 1)


chr12: 124428932
NCOR2
Promoter (1-2 kb)


chr3: 52468694
NISCH
Promoter (1-2 kb)


chr9: 124820937
OLFML2A
Distal Intergenic


chr22: 44049853
PARVB
Intron (ENST00000406477.7/29780, intron 2 of 13)


chr19: 3656250
PIP5K1C
Intron (ENST00000335312.7/23396, intron 6 of 17)


chr19: 3656275
PIP5K1C
Intron (ENST00000335312.7/23396, intron 6 of 17)


chr19: 3656172
PIP5K1C
Intron (ENST00000335312.7/23396, intron 6 of 17)


chr19: 3656178
PIP5K1C
Intron (ENST00000335312.7/23396, intron 6 of 17)


chr19: 3656369
PIP5K1C
Intron (ENST00000335312.7/23396, intron 6 of 17)


chr19: 3655804
PIP5K1C
Intron (ENST00000335312.7/23396, intron 6 of 17)


chr19: 3655921
PIP5K1C
Intron (ENST00000335312.7/23396, intron 6 of 17)


chr2: 264135
SH3YL1
Promoter (<=1 kb)


chr1: 232526599
SIPA1L2
Intron (ENST00000366630.5/57568, intron 1 of 21)


chr1: 54356528
SSBP3
Promoter (<=1 kb)


chr1: 36366641
STK40
Promoter (<=1 kb)


chr6: 10779357
TMEM14B
Intron (ENST00000480294.1/221711, intron 3 of 18)


chr20: 50015246
TRERNA1
Distal Intergenic


chr16: 70730157
VAC14
Intron (ENST00000568886.5/55697, intron 8 of 12)
















TABLE 17







Methylation sites associated with SCLC-P identified from RRBS suitable for a liquid biopsy assay









Methylation Site
GENE SYMBOL
Annotation





chr1: 33315055
A3GALT2
Intron (ENST00000588828.1/ENST00000588828.1, intron 1 of 1)


chr1: 33315062
A3GALT2
Intron (ENST00000588828.1/ENST00000588828.1, intron 1 of 1)


chr1: 33315063
A3GALT2
Intron (ENST00000588828.1/ENST00000588828.1, intron 1 of 1)


chr1: 33315101
A3GALT2
Intron (ENST00000588828.1/ENST00000588828.1, intron 1 of 1)


chr22: 42757869
A4GALT
Distal Intergenic


chr22: 42757892
A4GALT
Distal Intergenic


chr14: 22984092
AJUBA
Promoter (1-2 kb)


chr14: 22984101
AJUBA
Promoter (1-2 kb)


chr14: 22984111
AJUBA
Promoter (1-2 kb)


chr14: 22984144
AJUBA
Promoter (1-2 kb)


chr18: 26652681
AQP4-AS1
Intron (ENST00000580191.5/284252, intron 1 of 4)


chr12: 110245057
ATP2A2
Distal Intergenic


chr12: 110245058
ATP2A2
Distal Intergenic


chr16: 31109235
BCKDK
Promoter (<=1 kb)


chr1: 15207848
C1orf195
Intron (ENST00000428417.5/55092, intron 1 of 2)


chr10: 103479364
CALHM3
Promoter (<=1 kb)


chr12: 75306272
CAPS2
Exon (ENST00000547243.1/ENST00000547243.1, exon 1 of 1)


chr6: 21894804
CASC15
Intron (ENST00000671160.1/401237, intron 2 of 7)


chr6: 21894816
CASC15
Intron (ENST00000671160.1/401237, intron 2 of 7)


chr1: 50977120
CDKN2C
Distal Intergenic


chr11: 117794285
DSCAML1
Promoter (2-3 kb)


chr11: 117794300
DSCAML1
Promoter (2-3 kb)


chr11: 117794312
DSCAML1
Promoter (2-3 kb)


chr10: 22229200
EBLN1
Distal Intergenic


chr10: 22229203
EBLN1
Distal Intergenic


chr10: 22229207
EBLN1
Distal Intergenic


chr10: 22229209
EBLN1
Distal Intergenic


chr10: 22229211
EBLN1
Distal Intergenic


chr10: 22229213
EBLN1
Distal Intergenic


chr19: 11483715
ELAVL3
Promoter (2-3 kb)


chr19: 11483744
ELAVL3
Promoter (2-3 kb)


chr19: 11483821
ELAVL3
Promoter (2-3 kb)


chr19: 11483824
ELAVL3
Promoter (2-3 kb)


chr19: 11483826
ELAVL3
Promoter (2-3 kb)


chr19: 11483828
ELAVL3
Promoter (2-3 kb)


chr19: 11483877
ELAVL3
Promoter (2-3 kb)


chr19: 11483882
ELAVL3
Promoter (2-3 kb)


chr19: 11483887
ELAVL3
Promoter (2-3 kb)


chr19: 11483902
ELAVL3
Promoter (2-3 kb)


chr19: 11483903
ELAVL3
Promoter (2-3 kb)


chr19: 11483933
ELAVL3
Promoter (2-3 kb)


chr18: 5543758
EPB41L3
Promoter (<=1 kb)


chr1: 11636037
FBXO2
Intron (ENST00000642131.1/ENST00000642131.1, intron 1 of 1)


chr1: 239997697
FMN2
Distal Intergenic


chr1: 240092877
FMN2
Promoter (<=1 kb)


chr1: 240092884
FMN2
Promoter (1-2 kb)


chr9: 101738424
GRIN3A
Promoter (<=1 kb)


chr9: 101738450
GRIN3A
Promoter (<=1 kb)


chr12: 120967113
HNF1A-AS1
Intron (ENST00000619441.1/ENST00000619441.1, intron 1 of 1)


chr5: 5480537
ICE1
Intron (ENST00000296564.9/23379, intron 17 of 18)


chr5: 5480539
ICE1
Intron (ENST00000296564.9/23379, intron 17 of 18)


chr5: 2751058
IRX2
Promoter (<=1 kb)


chr5: 2751201
IRX2
Promoter (<=1 kb)


chr16: 19130411
ITPRIPL2
Intron (ENST00000568526.1/162073, intron 2 of 4)


chr11: 134072658
JAM3
Intron (ENST00000534549.5/83700, intron 1 of 2)


chr11: 134072677
JAM3
Intron (ENST00000534549.5/83700, intron 1 of 2)


chr7: 32907550
KBTBD2
Distal Intergenic


chr17: 75034158
KCTD2
Promoter (1-2 kb)


chr2: 23667161
KLHL29
Intron (ENST00000486442.6/114818, intron 5 of 13)


chr6: 21423591
LINC00581
Distal Intergenic


chr18: 49655943
LIPG
Distal Intergenic


chr20: 57407195
LOC100291105
Intron (ENST00000440234.6/55544, intron 2 of 2)


chr5: 51383057
LOC642366
Promoter (<=1 kb)


chr5: 51383086
LOC642366
Promoter (<=1 kb)


chr19: 5704447
LONP1
Intron (ENST00000587552.5/9361, intron 7 of 15)


chr6: 5213923
LYRM4
Promoter (2-3 kb)


chr1: 25603895
MAN1C1
Distal Intergenic


chr1: 25603905
MAN1C1
Distal Intergenic


chr5: 16179849
MARCHF11
Promoter (<=1 kb)


chr5: 16179857
MARCHF11
Promoter (<=1 kb)


chr5: 16179865
MARCHF11
Promoter (<=1 kb)


chr5: 16179878
MARCHF11
Promoter (<=1 kb)


chr5: 16179881
MARCHF11
Promoter (<=1 kb)


chr5: 16179883
MARCHF11
Promoter (<=1 kb)


chr5: 16179960
MARCHF11
Promoter (<=1 kb)


chr2: 239344172
MIR2467
Intron (ENST00000345617.7/9759, intron 2 of 26)


chr2: 239344189
MIR2467
Intron (ENST00000345617.7/9759, intron 2 of 26)


chr15: 74789232
MIR4513
Promoter (<=1 kb)


chr17: 27293362
MIR4522
Promoter (<=1 kb)


chr15: 89389866
MIR9-3HG
Promoter (2-3 kb)


chr13: 108495844
MYO16
Distal Intergenic


chr13: 108495845
MYO16
Distal Intergenic


chr13: 108495846
MYO16
Distal Intergenic


chr13: 108495847
MYO16
Distal Intergenic


chr13: 108495848
MYO16
Distal Intergenic


chr1: 164576888
PBX1
Promoter (<=1 kb)


chr1: 164576889
PBX1
Promoter (<=1 kb)


chr1: 164576897
PBX1
Promoter (<=1 kb)


chr1: 164576907
PBX1
Promoter (<=1 kb)


chr1: 164576909
PBX1
Promoter (<=1 kb)


chr3: 170182685
PHC3
Promoter (<=1 kb)


chr1: 113758109
PHTF1
Promoter (1-2 kb)


chr1: 113758121
PHTF1
Promoter (1-2 kb)


chr13: 72840708
PIBF1
Intron (ENST00000615625.1/10464, intron 2 of 8)


chr1: 6470978
PLEKHG5
Promoter (<=1 kb)


chr1: 6470979
PLEKHG5
Promoter (<=1 kb)


chr1: 6470980
PLEKHG5
Promoter (<=1 kb)


chr1: 6470981
PLEKHG5
Promoter (<=1 kb)


chr1: 6470982
PLEKHG5
Promoter (<=1 kb)


chr1: 6471004
PLEKHG5
Promoter (<=1 kb)


chr1: 6471154
PLEKHG5
Promoter (<=1 kb)


chr1: 6471412
PLEKHG5
Promoter (<=1 kb)


chr3: 52167456
POC1A
Distal Intergenic


chr12: 3491095
PRMT8
Promoter (<=1 kb)


chr12: 3491108
PRMT8
Promoter (<=1 kb)


chr12: 3491115
PRMT8
Promoter (<=1 kb)


chr18: 46028443
PSTPIP2
Exon (ENST00000591191.1/ENST00000591191.1, exon 1 of 1)


chr2: 130372287
PTPN18
Promoter (<=1 kb)


chr2: 130372663
PTPN18
Promoter (<=1 kb)


chr2: 130372713
PTPN18
Promoter (<=1 kb)


chr2: 130372851
PTPN18
Promoter (<=1 kb)


chr1: 21664061
RAP1GAP
Intron (ENST00000290101.8/5909, intron 1 of 26)


chr1: 21664104
RAP1GAP
Intron (ENST00000290101.8/5909, intron 1 of 26)


chr1: 21664105
RAP1GAP
Intron (ENST00000290101.8/5909, intron 1 of 26)


chr20: 63689809
RTEL1
Promoter (<=1 kb)


chr20: 63689822
RTEL1
Promoter (<=1 kb)


chr9: 136451683
SEC16A
Promoter (2-3 kb)


chr9: 136451687
SEC16A
Promoter (2-3 kb)


chr2: 85429488
SH2D6
Promoter (<=1 kb)


chr11: 47406945
SLC39A13
Promoter (<=1 kb)


chr15: 65045932
SLC51B
Promoter (<=1 kb)


chr3: 14401986
SLC6A6
Promoter (<=1 kb)


chr12: 130788705
STX2
Downstream (<1 kb)


chr7: 48002285
SUN3
Promoter (2-3 kb)


chr12: 109924012
TCHP
Intron (ENST00000544838.5/84260, intron 13 of 14)


chr12: 109924015
TCHP
Intron (ENST00000544838.5/84260, intron 13 of 14)


chr12: 109924087
TCHP
Intron (ENST00000544838.5/84260, intron 13 of 14)


chr12: 109924155
TCHP
Intron (ENST00000544838.5/84260, intron 13 of 14)


chr12: 109924248
TCHP
Intron (ENST00000544838.5/84260, intron 13 of 14)


chr1: 35578285
TFAP2E
Promoter (<=1 kb)


chr18: 23282431
TMEM241
Intron (ENST00000578790.5/85019, intron 2 of 3)


chr1: 6460633
TNFRSF25
Promoter (1-2 kb)


chr1: 6460653
TNFRSF25
Promoter (1-2 kb)


chr1: 6460894
TNFRSF25
Promoter (1-2 kb)


chr1: 6460918
TNFRSF25
Promoter (1-2 kb)


chr1: 6460934
TNFRSF25
Promoter (1-2 kb)


chr1: 6460935
TNFRSF25
Promoter (1-2 kb)


chr1: 6460947
TNFRSF25
Promoter (1-2 kb)


chr1: 6460956
TNFRSF25
Promoter (1-2 kb)


chr1: 6461061
TNFRSF25
Promoter (1-2 kb)


chr1: 6461087
TNFRSF25
Promoter (1-2 kb)


chr1: 6461096
TNFRSF25
Promoter (1-2 kb)


chr1: 6461190
TNFRSF25
Promoter (1-2 kb)


chr1: 6461192
TNFRSF25
Promoter (1-2 kb)


chr1: 6461254
TNFRSF25
Promoter (1-2 kb)


chr1: 6461265
TNFRSF25
Promoter (1-2 kb)


chr1: 6461279
TNFRSF25
Promoter (1-2 kb)


chr1: 6461288
TNFRSF25
Promoter (1-2 kb)


chr1: 6461304
TNFRSF25
Promoter (1-2 kb)


chr14: 45021208
TOGARAM1
Intron (ENST00000556239.5/54813, intron 1 of 2)


chr22: 38403885
TPTEP2
Distal Intergenic


chr22: 38403893
TPTEP2
Distal Intergenic


chr22: 38403895
TPTEP2
Distal Intergenic


chr22: 38403915
TPTEP2
Distal Intergenic


chr18: 79994148
TXNLAA
Intron (ENST00000585474.5/10907, intron 1 of 2)


chr12: 122875685
VPS37B
Exon (ENST00000623210.1/ENST00000623210.1, exon 1 of 1)


chr19: 56155326
ZNF444
Promoter (1-2 kb)


chr19: 11483959
ZNF653
Promoter (2-3 kb)


chr19: 11483967
ZNF653
Promoter (2-3 kb)


chr19: 11483973
ZNF653
Promoter (2-3 kb)


chr19: 56309806
ZSCAN5A
Intron (ENST00000593106.5/79149, intron 2 of 4)
















TABLE 18







Methylation sites associated with SCLC-I identified from RRBS suitable for a liquid biopsy assay









Methylation Site
GENE SYMBOL
Annotation





chr16: 52621872
CASC16
Intron (ENST00000652959.1/643714, intron 3 of 6)


chr16: 52621873
CASC16
Intron (ENST00000652959.1/643714, intron 3 of 6)


chr11: 64299647
CATSPERZ
Promoter (<=1 kb)


chr11: 64299653
CATSPERZ
Promoter (<=1 kb)


chr11: 64299676
CATSPERZ
Promoter (<=1 kb)


chr11: 64299686
CATSPERZ
Promoter (<=1 kb)


chr11: 64299688
CATSPERZ
Promoter (<=1 kb)


chr4: 10717468
CLNK
Distal Intergenic


chr4: 10717488
CLNK
Distal Intergenic


chr7: 146562076
CNTNAP2
Intron (ENST00000625365.2/26047, intron 2 of 3)


chr7: 146735323
CNTNAP2
Intron (ENST00000625365.2/26047, intron 2 of 3)


chr7: 147640913
CNTNAP2
Promoter (1-2 kb)


chr17: 7204895
DLG4
Promoter (<=1 kb)


chr2: 232486759
ECEL1
Promoter (<=1 kb)


chr2: 232486768
ECEL1
Promoter (<=1 kb)


chr2: 221307744
EPHA4
Exon (ENST00000650956.1/ENST00000650956.1, exon 1 of 2)


chr11: 725837
EPS8L2
Promoter (<=1 kb)


chr11: 726066
EPS8L2
Promoter (<=1 kb)


chr11: 726081
EPS8L2
Promoter (<=1 kb)


chr11: 726088
EPS8L2
Promoter (<=1 kb)


chr11: 726100
EPS8L2
Promoter (<=1 kb)


chr11: 726121
EPS8L2
Promoter (<=1 kb)


chr11: 726122
EPS8L2
Promoter (<=1 kb)


chr11: 726130
EPS8L2
Promoter (<=1 kb)


chr11: 726169
EPS8L2
Promoter (<=1 kb)


chr11: 726187
EPS8L2
Promoter (<=1 kb)


chr11: 726192
EPS8L2
Promoter (<=1 kb)


chr11: 726275
EPS8L2
Promoter (<=1 kb)


chr11: 726278
EPS8L2
Promoter (<=1 kb)


chr11: 726289
EPS8L2
Promoter (<=1 kb)


chr11: 726291
EPS8L2
Promoter (<=1 kb)


chr11: 726293
EPS8L2
Promoter (<=1 kb)


chr11: 726333
EPS8L2
Promoter (<=1 kb)


chr11: 726336
EPS8L2
Promoter (<=1 kb)


chr11: 726345
EPS8L2
Promoter (<=1 kb)


chr11: 726367
EPS8L2
Promoter (<=1 kb)


chr11: 726387
EPS8L2
Promoter (<=1 kb)


chr11: 726397
EPS8L2
Promoter (<=1 kb)


chr11: 726408
EPS8L2
Promoter (<=1 kb)


chr11: 726419
EPS8L2
Promoter (<=1 kb)


chr11: 726491
EPS8L2
Promoter (<=1 kb)


chr11: 726497
EPS8L2
Promoter (<=1 kb)


chr11: 726561
EPS8L2
Promoter (<=1 kb)


chr11: 726611
EPS8L2
Promoter (<=1kb)


chr6: 139771860
FILNC1
Intron (ENST00000644936.1/100132735, intron 1 of 2)


chr21: 44931508
ITGB2
Promoter (<=1 kb)


chr8: 11059296
LOC101929269
Intron (ENST00000416569.3/286046, intron 1 of 2)


chr19: 46016130
MIR769
Promoter (2-3 kb)


chr19: 46016136
MIR769
Promoter (2-3 kb)


chr19: 46016138
MIR769
Promoter (2-3 kb)


chr19: 46016139
MIR769
Promoter (2-3 kb)


chr19: 46016142
MIR769
Promoter (2-3 kb)


chr19: 46016144
MIR769
Promoter (2-3 kb)


chr19: 46016145
MIR769
Promoter (2-3 kb)


chr19: 46016146
MIR769
Promoter (2-3 kb)


chr19: 46016147
MIR769
Promoter (2-3 kb)


chr19: 46016148
MIR769
Promoter (2-3 kb)


chr19: 46016149
MIR769
Promoter (2-3 kb)


chr3: 175259809
NAALADL2
Intron (ENST00000424690.1/100874244, intron 1 of 2)


chr3: 175854326
NAALADL2-AS1
Distal Intergenic


chr9: 93133105
NINJ1
Promoter (1-2 kb)


chr1: 163423133
NUF2
Exon (ENST00000430516.1/ENST00000430516.1, exon 1 of 2)


chr1: 163423134
NUF2
Exon (ENST00000430516.1/ENST00000430516.1, exon 1 of 2)


chr1: 163423194
NUF2
Distal Intergenic


chr1: 163423199
NUF2
Distal Intergenic


chr1: 163677704
NUF2
Distal Intergenic


chr1: 163692555
NUF2
Distal Intergenic


chr19: 2290919
PEAK3
Exon (ENST00000585527.1/ENST00000585527.1, exon 1 of 1)


chr19: 2290925
PEAK3
Exon (ENST00000585527.1/ENST00000585527.1, exon 1 of 1)


chr19: 2290978
PEAK3
Exon (ENST00000585527.1/ENST00000585527.1, exon 1 of 1)


chr19: 2290996
PEAK3
Exon (ENST00000585527.1/ENST00000585527.1, exon 1 of 1)


chr19: 2290999
PEAK3
Exon (ENST00000585527.1/ENST00000585527.1, exon 1 of 1)


chr19: 2291021
PEAK3
Exon (ENST00000585527.1/ENST00000585527.1, exon 1 of 1)


chr20: 59605599
PHACTR3
Promoter (1-2 kb)


chr20: 59605612
PHACTR3
Promoter (1-2 kb)


chr20: 59605622
PHACTR3
Promoter (1-2 kb)


chr20: 59605632
PHACTR3
Promoter (1-2 kb)


chr20: 59605688
PHACTR3
Promoter (1-2 kb)


chr20: 59605692
PHACTR3
Promoter (1-2 kb)


chr20: 59605706
PHACTR3
Promoter (1-2 kb)


chr20: 59605758
PHACTR3
Promoter (1-2 kb)


chr2: 231707590
PTMA
Promoter (<=1 kb)


chr4: 81586509
RASGEF1B
Intron (ENST00000638048.1/153020, intron 4 of 16)


chr12: 97403582
RMST
Distal Intergenic


chr12: 97403620
RMST
Distal Intergenic


chr12: 97403630
RMST
Distal Intergenic


chr12: 98311179
SLC9A7P1
Distal Intergenic


chr11: 130160086
ST14
Promoter (<=1 kb)


chr16: 52395111
TOX3
Distal Intergenic


chr16: 52504937
TOX3
Intron (ENST00000563091.1/27324, intron 1 of 3)


chr16: 52505114
TOX3
Intron (ENST00000563091.1/27324, intron 1 of 3)
















TABLE 19







Methylation sites capable of differentiating SCLC-A


from SCLC-N identified from xenograft samples









Methylation Site
GENE SYMBOL
Annotation





chr1: 1048828
AGRN
Promoter (<=1kb)


chr1: 1048892
AGRN
Promoter (<=1kb)


chr1: 1048899
AGRN
Promoter (<=1kb)


chr1: 1048926
AGRN
Promoter (<=1kb)


chr1: 1048928
AGRN
Promoter (<=1kb)


chr1: 1048940
AGRN
Promoter (<=1kb)


chr1: 1224106
SDF4
Promoter (2-3kb)


chr1: 1345500
DVL1
Intron (ENST00000378891.9/1855, intron 1 of 14)


chr1: 1345502
DVL1
Intron (ENST00000378891.9/1855, intron 1 of 14)


chr1: 1345520
DVL1
Intron (ENST00000378891.9/1855, intron 1 of 14)


chr1: 1345521
DVL1
Intron (ENST00000378891.9/1855, intron 1 of 14)


chr1: 2204525
FAAP20
Promoter (<=1kb)


chr1: 2204544
FAAP20
Promoter (<=1kb)


chr1: 2204588
FAAP20
Promoter (<=1kb)


chr1: 2204592
FAAP20
Promoter (<=1kb)


chr1: 2204595
FAAP20
Promoter (<=1kb)


chr1: 2204598
FAAP20
Promoter (<=1kb)


chr1: 2204676
FAAP20
Promoter (<=1kb)


chr1: 2204721
FAAP20
Promoter (<=1kb)


chr1: 2204778
FAAP20
Promoter (<=1kb)


chr1: 2204779
FAAP20
Promoter (<=1kb)


chr1: 2204782
FAAP20
Promoter (<=1kb)


chr1: 2204799
FAAP20
Promoter (<=1kb)


chr1: 2204802
FAAP20
Promoter (<=1kb)


chr1: 2306607
SKI
Promoter (2-3kb)


chr1: 2306609
SKI
Promoter (2-3kb)


chr1: 2306615
SKI
Promoter (2-3kb)


chr1: 3101046
MIR4251
Intron (ENST00000511072.5/63976, intron 1 of 15)


chr1: 3101087
MIR4251
Intron (ENST00000511072.5/63976, intron 1 of 15)


chr1: 3238646
PRDM16
Promoter (<=1kb)


chr1: 3524220
MEGF6
Exon (ENST00000356575.9/1953, exon 5 of 37)


chr1: 3524231
MEGF6
Exon (ENST00000356575.9/1953, exon 5 of 37)


chr1: 3524238
MEGF6
Exon (ENST00000356575.9/1953, exon 5 of 37)


chr1: 3772826
SMIM1
Promoter (<=1kb)


chr1: 3772830
SMIM1
Promoter (<=1kb)


chr1: 3772845
SMIM1
Promoter (<=1kb)


chr1: 3772853
SMIM1
Promoter (<=1kb)


chr1: 3772855
SMIM1
Promoter (<=1kb)


chr1: 3772861
SMIM1
Promoter (<=1kb)


chr1: 4711117
AJAP1
Promoter (<=1kb)


chr1: 4711119
AJAP1
Promoter (<=1kb)


chr1: 6473328
PLEKHG5
Promoter (1-2kb)


chr1: 6473356
PLEKHG5
Promoter (1-2kb)


chr1: 6473407
PLEKHG5
Promoter (1-2kb)


chr1: 6473425
PLEKHG5
Promoter (1-2kb)


chr1: 6473439
PLEKHG5
Promoter (1-2kb)


chr1: 6473441
PLEKHG5
Promoter (1-2kb)


chr1: 6473442
PLEKHG5
Promoter (1-2kb)


chr1: 7574644
CAMTA1
Intron (ENST00000303635.12/23261, intron 6 of 22)


chr1: 7574659
CAMTA1
Intron (ENST00000303635.12/23261, intron 6 of 22)


chr1: 7574678
CAMTA1
Intron (ENST00000303635.12/23261, intron 6 of 22)


chr1: 10658845
CASZ1
Promoter (2-3kb)


chr1: 10658877
CASZ1
Promoter (2-3kb)


chr1: 10665296
CASZ1
Exon (ENST00000377022.8/54897, exon 5 of 21)


chr1: 10665323
CASZ1
Exon (ENST00000377022.8/54897, exon 5 of 21)


chr1: 10665324
CASZ1
Exon (ENST00000377022.8/54897, exon 5 of 21)


chr1: 10665334
CASZ1
Exon (ENST00000377022.8/54897, exon 5 of 21)


chr1: 10665335
CASZ1
Exon (ENST00000377022.8/54897, exon 5 of 21)


chr1: 10665351
CASZ1
Exon (ENST00000377022.8/54897, exon 5 of 21)


chr1: 10665356
CASZ1
Exon (ENST00000377022.8/54897, exon 5 of 21)


chr1: 10665391
CASZ1
Exon (ENST00000377022.8/54897, exon 5 of 21)


chr1: 10665392
CASZ1
Exon (ENST00000377022.8/54897, exon 5 of 21)


chr1: 10665448
CASZ1
Exon (ENST00000377022.8/54897, exon 5 of 21)


chr1: 10665469
CASZ1
Exon (ENST00000377022.8/54897, exon 5 of 21)


chr1: 10665515
CASZ1
Exon (ENST00000377022.8/54897, exon 5 of 21)


chr1: 10665523
CASZ1
Exon (ENST00000377022.8/54897, exon 5 of 21)


chr1: 10665531
CASZ1
Exon (ENST00000377022.8/54897, exon 5 of 21)


chr1: 10665547
CASZ1
Exon (ENST00000377022.8/54897, exon 5 of 21)


chr1: 10744882
CASZ1
Intron (ENST00000377022.8/54897, intron 2 of 20)


chr1: 10744889
CASZ1
Intron (ENST00000377022.8/54897, intron 2 of 20)


chr1: 10744895
CASZ1
Intron (ENST00000377022.8/54897, intron 2 of 20)


chr1: 10744915
CASZ1
Intron (ENST00000377022.8/54897, intron 2 of 20)


chr1: 10744948
CASZ1
Intron (ENST00000377022.8/54897, intron 2 of 20)


chr1: 10814011
CASZ1
Distal Intergenic


chr1: 10958789
C1orf127
Intron (ENST00000418570.6/148345, intron 1 of 7)


chr1: 10958790
C1orf127
Intron (ENST00000418570.6/148345, intron 1 of 7)


chr1: 10958875
C1orf127
Intron (ENST00000418570.6/148345, intron 1 of 7)


chr1: 10958941
C1orf127
Intron (ENST00000418570.6/148345, intron 1 of 7)


chr1: 13901406
KAZN
Intron (ENST00000636564.1/ENST00000636564.1, intron 1 of 2)


chr1: 14420671
KAZN-AS1
Promoter (<=1kb)


chr1: 14420679
KAZN-AS1
Promoter (<=1kb)


chr1: 15467505
CELA2B
Promoter (1-2kb)


chr1: 15467507
CELA2B
Promoter (1-2kb)


chr1: 15467524
CELA2B
Promoter (1-2kb)


chr1: 24322601
GRHL3
Promoter (<=1kb)


chr1: 24322603
GRHL3
Promoter (<=1kb)


chr1: 24322614
GRHL3
Promoter (<=1kb)


chr1: 24322620
GRHL3
Promoter (<=1kb)


chr1: 24322636
GRHL3
Promoter (<=1kb)


chr1: 24642007
SRRM1
Promoter (<=1kb)


chr1: 24642020
SRRM1
Promoter (<=1kb)


chr1: 24642021
SRRM1
Promoter (<=1kb)


chr1: 24642029
SRRM1
Promoter (<=1kb)


chr1: 24642030
SRRM1
Promoter (<=1kb)


chr1: 24642036
SRRM1
Promoter (<=1kb)


chr1: 24642037
SRRM1
Promoter (<=1kb)


chr1: 24642042
SRRM1
Promoter (<=1kb)


chr1: 24642043
SRRM1
Promoter (<=1kb)


chr1: 26863494
SFN
Promoter (<=1kb)


chr1: 26863500
SFN
Promoter (<=1kb)


chr1: 26863501
SFN
Promoter (<=1kb)


chr1: 26863506
SFN
Promoter (<=1kb)


chr1: 26863507
SFN
Promoter (<=1kb)


chr1: 26863546
SFN
Promoter (<=1kb)


chr1: 26863597
SFN
Promoter (<=1kb)


chr1: 26863598
SFN
Promoter (<=1kb)


chr1: 29259879
PTPRU
Promoter (<=1kb)


chr1: 29259884
PTPRU
Promoter (<=1kb)


chr1: 31176418
NKAIN1
Distal Intergenic


chr1: 31176426
NKAIN1
Distal Intergenic


chr1: 31176444
NKAIN1
Distal Intergenic


chr1: 31714647
COL16A1
Distal Intergenic


chr1: 31714655
COL16A1
Distal Intergenic


chr1: 31714656
COL16A1
Distal Intergenic


chr1: 31714688
COL16A1
Distal Intergenic


chr1: 31714693
COL16A1
Distal Intergenic


chr1: 31714706
COL16A1
Distal Intergenic


chr1: 34865995
SMIM12
3′ UTR


chr1: 34866000
SMIM12
3′ UTR


chr1: 34866002
SMIM12
3′ UTR


chr1: 34866017
SMIM12
3′ UTR


chr1: 34866020
SMIM12
3′ UTR


chr1: 34866103
SMIM12
Exon (ENST00000235180.4/58512, exon 10 of 10)


chr1: 34866118
SMIM12
Exon (ENST00000235180.4/58512, exon 10 of 10)


chr1: 34866127
SMIM12
Exon (ENST00000235180.4/58512, exon 10 of 10)


chr1: 36161139
MAP7D1
Intron (ENST00000429533.6/55700, intron 1 of 5)


chr1: 36161140
MAP7D1
Intron (ENST00000429533.6/55700, intron 1 of 5)


chr1: 38559563
LINC01685
Distal Intergenic


chr1: 38559572
LINC01685
Distal Intergenic


chr1: 38559577
LINC01685
Distal Intergenic


chr1: 40802458
KCNQ4
Intron (ENST00000347132.10/9132, intron 1 of 13)


chr1: 40802464
KCNQ4
Intron (ENST00000347132.10/9132, intron 1 of 13)


chr1: 40802488
KCNQ4
Intron (ENST00000347132.10/9132, intron 1 of 13)


chr1: 44576768
MIR5584
Intron (ENST00000355387.6/55182, intron 2 of 14)


chr1: 44588236
RNF220
Intron (ENST00000355387.6/55182, intron 2 of 14)


chr1: 44588256
RNF220
Intron (ENST00000355387.6/55182, intron 2 of 14)


chr1: 44603252
RNF220
Intron (ENST00000355387.6/55182, intron 2 of 14)


chr1: 44603267
RNF220
Intron (ENST00000355387.6/55182, intron 2 of 14)


chr1: 47230856
TAL1
Promoter (<=1kb)


chr1: 47230862
TAL1
Promoter (<=1kb)


chr1: 47230868
TAL1
Promoter (<=1kb)


chr1: 47230874
TAL1
Promoter (<=1kb)


chr1: 47230877
TAL1
Promoter (<=1kb)


chr1: 47230894
TAL1
Promoter (<=1kb)


chr1: 50416355
DMRTA2
Downstream (1-2kb)


chr1: 50416362
DMRTA2
Downstream (1-2kb)


chr1: 50416430
DMRTA2
Downstream (1-2kb)


chr1: 50416561
DMRTA2
Downstream (<1kb)


chr1: 50416568
DMRTA2
Downstream (<1kb)


chr1: 54980471
TMEM61
Promoter (<=1kb)


chr1: 54980476
TMEM61
Promoter (<=1kb)


chr1: 54980498
TMEM61
Promoter (<=1kb)


chr1: 54980503
TMEM61
Promoter (<=1kb)


chr1: 54980505
TMEM61
Promoter (<=1kb)


chr1: 54980513
TMEM61
Promoter (<=1kb)


chr1: 54980533
TMEM61
Promoter (<=1kb)


chr1: 54980535
TMEM61
Promoter (<=1kb)


chr1: 54980543
TMEM61
Promoter (<=1kb)


chr1: 54980550
TMEM61
Promoter (<=1kb)


chr1: 54980553
TMEM61
Promoter (<=1kb)


chr1: 54980555
TMEM61
Promoter (<=1kb)


chr1: 54980714
TMEM61
Promoter (<=1kb)


chr1: 54980716
TMEM61
Promoter (<=1kb)


chr1: 54980728
TMEM61
Promoter (<=1kb)


chr1: 54980735
TMEM61
Promoter (<=1kb)


chr1: 54980736
TMEM61
Promoter (<=1kb)


chr1: 54980752
TMEM61
Promoter (<=1kb)


chr1: 54980753
TMEM61
Promoter (<=1kb)


chr1: 54980754
TMEM61
Promoter (<=1kb)


chr1: 54980755
TMEM61
Promoter (<=1kb)


chr1: 54980762
TMEM61
Promoter (<=1kb)


chr1: 54980764
TMEM61
Promoter (<=1kb)


chr1: 54980773
TMEM61
Promoter (<=1kb)


chr1: 54980778
TMEM61
Promoter (<=1kb)


chr1: 54980782
TMEM61
Promoter (<=1kb)


chr1: 61054727
NFIA
Promoter (<=1kb)


chr1: 61054728
NFIA
Promoter (<=1kb)


chr1: 61054749
NFIA
Promoter (<=1kb)


chr1: 61054752
NFIA
Promoter (<=1kb)


chr1: 61054757
NFIA
Promoter (<=1kb)


chr1: 63330395
MIR6068
Distal Intergenic


chr1: 63330398
MIR6068
Distal Intergenic


chr1: 63330404
MIR6068
Distal Intergenic


chr1: 63330412
MIR6068
Distal Intergenic


chr1: 63330419
MIR6068
Distal Intergenic


chr1: 63330421
MIR6068
Distal Intergenic


chr1: 75797204
MSH4
Promoter (<=1kb)


chr1: 75797205
MSH4
Promoter (<=1kb)


chr1: 75797206
MSH4
Promoter (<=1kb)


chr1: 75797207
MSH4
Promoter (<=1kb)


chr1: 90836081
LINC02609
Promoter (<=1kb)


chr1: 90836087
LINC02609
Promoter (<=1kb)


chr1: 90836091
LINC02609
Promoter (<=1kb)


chr1: 90836094
LINC02609
Promoter (<=1kb)


chr1: 90836113
LINC02609
Promoter (<=1kb)


chr1: 90836117
LINC02609
Promoter (<=1kb)


chr1: 101256143
S1PR1
Distal Intergenic


chr1: 108675439
HENMT1
Distal Intergenic


chr1: 108675464
HENMT1
Distal Intergenic


chr1: 109274863
CELSR2
3′ UTR


chr1: 109274868
CELSR2
3′ UTR


chr1: 109274870
CELSR2
3′ UTR


chr1: 111961251
KCND3
Intron (ENST00000369697.5/3752, intron 1 of 5)


chr1: 113422496
MAGI3
Intron (ENST00000307546.14/260425, intron 1 of 20)


chr1: 116168253
MAB21L3
Distal Intergenic


chr1: 116168278
MAB21L3
Distal Intergenic


chr1: 116168454
MAB21L3
Distal Intergenic


chr1: 116168455
MAB21L3
Distal Intergenic


chr1: 116168456
MAB21L3
Distal Intergenic


chr1: 116168457
MAB21L3
Distal Intergenic


chr1: 116168477
MAB21L3
Distal Intergenic


chr1: 116168478
MAB21L3
Distal Intergenic


chr1: 143654112
RNVU1-17
Distal Intergenic


chr1: 143654118
RNVU1-17
Distal Intergenic


chr1: 143691944
RNVU1-17
Distal Intergenic


chr1: 143691957
RNVU1-17
Distal Intergenic


chr1: 149813047
H3C13
Promoter (<=1kb)


chr1: 149813051
H3C13
Promoter (<=1kb)


chr1: 150716911
HORMAD1
Intron (ENST00000368995.8/84072, intron 3 of 12)


chr1: 151473479
POGZ
Distal Intergenic


chr1: 151473485
POGZ
Distal Intergenic


chr1: 151473487
POGZ
Distal Intergenic


chr1: 151473495
POGZ
Distal Intergenic


chr1: 151473497
POGZ
Distal Intergenic


chr1: 151473500
POGZ
Distal Intergenic


chr1: 151473502
POGZ
Distal Intergenic


chr1: 151473584
POGZ
Distal Intergenic


chr1: 151473591
POGZ
Distal Intergenic


chr1: 151473605
POGZ
Distal Intergenic


chr1: 151473609
POGZ
Distal Intergenic


chr1: 151769408
OAZ3
Promoter (2-3kb)


chr1: 154502739
TDRD10
Promoter (<=1kb)


chr1: 154502777
TDRD10
Promoter (<=1kb)


chr1: 154502794
TDRD10
Promoter (<=1kb)


chr1: 154502799
TDRD10
Promoter (<=1kb)


chr1: 154502809
TDRD10
Promoter (<=1kb)


chr1: 154502820
TDRD10
Promoter (<=1kb)


chr1: 154502824
TDRD10
Promoter (<=1kb)


chr1: 156077503
MEX3A
Exon (ENST00000532414.3/92312, exon 2 of 2)


chr1: 160371182
NHLH1
3′ UTR


chr1: 160371202
NHLH1
3′ UTR


chr1: 164792823
PBX1
Promoter (<=1kb)


chr1: 164792824
PBX1
Promoter (<=1kb)


chr1: 170661589
PRRX1
Promoter (1-2kb)


chr1: 170661593
PRRX1
Promoter (1-2kb)


chr1: 170661600
PRRX1
Promoter (1-2kb)


chr1: 170661602
PRRX1
Promoter (1-2kb)


chr1: 170661603
PRRX1
Promoter (1-2kb)


chr1: 170661605
PRRX1
Promoter (1-2kb)


chr1: 170661606
PRRX1
Promoter (1-2kb)


chr1: 170661614
PRRX1
Promoter (1-2kb)


chr1: 175907228
LINC01657
Intron (ENST00000426575.2/ENST00000426575.2, intron 2 of 2)


chr1: 175907235
LINC01657
Intron (ENST00000426575.2/ENST00000426575.2, intron 2 of 2)


chr1: 175907238
LINC01657
Intron (ENST00000426575.2/ENST00000426575.2, intron 2 of 2)


chr1: 179138847
ABL2
Intron (ENST00000367623.8/27, intron 1 of 10)


chr1: 179138848
ABL2
Intron (ENST00000367623.8/27, intron 1 of 10)


chr1: 179138917
ABL2
Intron (ENST00000367623.8/27, intron 1 of 10)


chr1: 179138918
ABL2
Intron (ENST00000367623.8/27, intron 1 of 10)


chr1: 179138924
ABL2
Intron (ENST00000367623.8/27, intron 1 of 10)


chr1: 179138925
ABL2
Intron (ENST00000367623.8/27, intron 1 of 10)


chr1: 184942664
NIBAN1
Intron (ENST00000367511.4/116496, intron 1 of 13)


chr1: 201127109
ASCL5
5′ UTR


chr1: 201127206
ASCL5
Distal Intergenic


chr1: 202010615
ELF3
Promoter (<=1kb)


chr1: 202010620
ELF3
Promoter (<=1kb)


chr1: 202010636
ELF3
Promoter (<=1kb)


chr1: 202010637
ELF3
Promoter (<=1kb)


chr1: 202010646
ELF3
Promoter (<=1kb)


chr1: 202010647
ELF3
Promoter (<=1kb)


chr1: 202010666
ELF3
Promoter (<=1kb)


chr1: 202010673
ELF3
Promoter (<=1kb)


chr1: 205343546
KLHDC8A
Promoter (<=1kb)


chr1: 205343560
KLHDC8A
Promoter (<=1kb)


chr1: 205343567
KLHDC8A
Promoter (<=1kb)


chr1: 205343712
KLHDC8A
Promoter (<=1kb)


chr1: 205343713
KLHDC8A
Promoter (<=1kb)


chr1: 205343716
KLHDC8A
Promoter (<=1kb)


chr1: 205343717
KLHDC8A
Promoter (<=1kb)


chr1: 205343751
KLHDC8A
Promoter (<=1kb)


chr1: 205343752
KLHDC8A
Promoter (<=1kb)


chr1: 205343758
KLHDC8A
Promoter (<=1kb)


chr1: 205343759
KLHDC8A
Promoter (<=1kb)


chr1: 205343768
KLHDC8A
Promoter (<=1kb)


chr1: 205343769
KLHDC8A
Promoter (<=1kb)


chr1: 205343835
KLHDC8A
Promoter (<=1kb)


chr1: 205343837
KLHDC8A
Promoter (<=1kb)


chr1: 205343846
KLHDC8A
Promoter (<=1kb)


chr1: 205343853
KLHDC8A
Promoter (<=1kb)


chr1: 205343864
KLHDC8A
Promoter (<=1kb)


chr1: 230839344
C1orf198
3′ UTR


chr1: 230839348
C1orf198
3′ UTR


chr1: 230839361
C1orf198
3′ UTR


chr1: 230839364
C1orf198
3′ UTR


chr1: 245234766
KIF26B-AS1
Promoter (<=1kb)


chr1: 245234785
KIF26B-AS1
Promoter (<=1kb)


chr1: 245234788
KIF26B-AS1
Promoter (<=1kb)


chr1: 245234801
KIF26B-AS1
Promoter (<=1kb)


chr10: 42898212
LINC02623
Distal Intergenic


chr10: 42898220
LINC02623
Distal Intergenic


chr10: 42898225
LINC02623
Distal Intergenic


chr10: 75398841
ZNF503
Promoter (2-3kb)


chr10: 75398847
ZNF503
Promoter (2-3kb)


chr10: 75398854
ZNF503
Promoter (2-3kb)


chr10: 75398863
ZNF503
Promoter (2-3kb)


chr10: 100741985
PAX2
Intron (ENST00000553492.5/5076, intron 1 of 3)


chr10: 100741996
PAX2
Intron (ENST00000553492.5/5076, intron 1 of 3)


chr10: 100741998
PAX2
Intron (ENST00000553492.5/5076, intron 1 of 3)


chr10: 100742013
PAX2
Intron (ENST00000553492.5/5076, intron 1 of 3)


chr10: 100742015
PAX2
Intron (ENST00000553492.5/5076, intron 1 of 3)


chr10: 100742025
PAX2
Intron (ENST00000553492.5/5076, intron 1 of 3)


chr10: 100742026
PAX2
Intron (ENST00000553492.5/5076, intron 1 of 3)


chr10: 100742045
PAX2
Intron (ENST00000553492.5/5076, intron 1 of 3)


chr10: 102485644
ACTR1A
Promoter (1-2kb)


chr10: 102485662
ACTR1A
Promoter (1-2kb)


chr10: 102485674
ACTR1A
Promoter (1-2kb)


chr10: 102485682
ACTR1A
Promoter (1-2kb)


chr10: 102485696
ACTR1A
Promoter (1-2kb)


chr10: 102485710
ACTR1A
Promoter (1-2kb)


chr10: 116670071
C10orf82
Promoter (<=1kb)


chr10: 116670073
C10orf82
Promoter (<=1kb)


chr10: 117535066
EMX2OS
Intron (ENST00000551288.5/196047, intron 2 of 3)


chr10: 117535091
EMX2OS
Intron (ENST00000551288.5/196047, intron 2 of 3)


chr10: 117535092
EMX2OS
Intron (ENST00000551288.5/196047, intron 2 of 3)


chr10: 117535329
EMX2OS
Intron (ENST00000551288.5/196047, intron 2 of 3)


chr10: 117535336
EMX2OS
Intron (ENST00000551288.5/196047, intron 2 of 3)


chr10: 117535352
EMX2OS
Intron (ENST00000551288.5/196047, intron 2 of 3)


chr10: 117535357
EMX2OS
Intron (ENST00000551288.5/196047, intron 2 of 3)


chr10: 117535366
EMX2OS
Intron (ENST00000551288.5/196047, intron 2 of 3)


chr10: 117535389
EMX2OS
Intron (ENST00000551288.5/196047, intron 2 of 3)


chr10: 117535393
EMX2OS
Intron (ENST00000551288.5/196047, intron 2 of 3)


chr10: 117535397
EMX2OS
Intron (ENST00000551288.5/196047, intron 2 of 3)


chr10: 117535399
EMX2OS
Intron (ENST00000551288.5/196047, intron 2 of 3)


chr10: 119541831
RGS10
Promoter (<=1kb)


chr10: 119541833
RGS10
Promoter (<=1kb)


chr10: 127424596
NPS
Intron (ENST00000280333.9/1793, intron 46 of 51)


chr10: 127424611
NPS
Intron (ENST00000280333.9/1793, intron 46 of 51)


chr10: 127424672
NPS
Intron (ENST00000280333.9/1793, intron 46 of 51)


chr10: 127424674
NPS
Intron (ENST00000280333.9/1793, intron 46 of 51)


chr10: 129580062
MGMT
Intron (ENST00000306010.8/4255, intron 2 of 4)


chr10: 129580113
MGMT
Intron (ENST00000306010.8/4255, intron 2 of 4)


chr10: 132065569
JAKMIP3
Promoter (<=1kb)


chr10: 132065581
JAKMIP3
Promoter (<=1kb)


chr10: 132065585
JAKMIP3
Promoter (<=1kb)


chr10: 132065597
JAKMIP3
Promoter (<=1kb)


chr10: 132065608
JAKMIP3
Promoter (<=1kb)


chr10: 132295081
STK32C
Intron (ENST00000368620.2/282974, intron 1 of 3)


chr10: 132295110
STK32C
Intron (ENST00000368620.2/282974, intron 1 of 3)


chr10: 132295119
STK32C
Intron (ENST00000368620.2/282974, intron 1 of 3)


chr10: 132295120
STK32C
Intron (ENST00000368620.2/282974, intron 1 of 3)


chr10: 132685767
INPP5A
Intron (ENST00000423490.5/3632, intron 2 of 5)


chr10: 132685769
INPP5A
Intron (ENST00000423490.5/3632, intron 2 of 5)


chr10: 132685807
INPP5A
Intron (ENST00000423490.5/3632, intron 2 of 5)


chr10: 132785047
NKX6-2
Promoter (1-2kb)


chr10: 132785054
NKX6-2
Promoter (1-2kb)


chr10: 132785056
NKX6-2
Promoter (1-2kb)


chr10: 132785060
NKX6-2
Promoter (1-2kb)


chr11: 2211321
MIR4686
Distal Intergenic


chr11: 2211334
MIR4686
Distal Intergenic


chr11: 2575187
KCNQ1
Intron (ENST00000646564.1/3784, intron 2 of 10)


chr11: 2575220
KCNQ1
Intron (ENST00000646564.1/3784, intron 2 of 10)


chr11: 2575224
KCNQ1
Intron (ENST00000646564.1/3784, intron 2 of 10)


chr11: 2575231
KCNQ1
Intron (ENST00000646564.1/3784, intron 2 of 10)


chr11: 14091669
SPON1
Intron (ENST00000576479.4/10418, intron 5 of 15)


chr11: 14091678
SPON1
Intron (ENST00000576479.4/10418, intron 5 of 15)


chr11: 14091682
SPON1
Intron (ENST00000576479.4/10418, intron 5 of 15)


chr11: 32333891
WT1
Intron (ENST00000525689.2/ENST00000525689.2, intron 1 of 1)


chr11: 32333902
WT1
Intron (ENST00000525689.2/ENST00000525689.2, intron 1 of 1)


chr11: 32333905
WT1
Intron (ENST00000525689.2/ENST00000525689.2, intron 1 of 1)


chr11: 32434782
WT1
Promoter (<=1kb)


chr11: 32434794
WT1
Promoter (<=1kb)


chr11: 32434805
WT1
Promoter (<=1kb)


chr11: 33406359
KIAA1549L
Intron (ENST00000658780.1/25758, intron 1 of 20)


chr11: 33406375
KIAA1549L
Intron (ENST00000658780.1/25758, intron 1 of 20)


chr11: 33406381
KIAA1549L
Intron (ENST00000658780.1/25758, intron 1 of 20)


chr11: 35420544
SLC1A2
Promoter (<=1kb)


chr11: 35420552
SLC1A2
Promoter (<=1kb)


chr11: 35420553
SLC1A2
Promoter (<=1kb)


chr11: 35420574
SLC1A2
Promoter (<=1kb)


chr11: 35420575
SLC1A2
Promoter (<=1kb)


chr11: 35420583
SLC1A2
Promoter (<=1kb)


chr11: 43581402
MIR129-2
Promoter (<=1kb)


chr11: 43581404
MIR129-2
Promoter (<=1kb)


chr11: 43581416
MIR129-2
Promoter (<=1kb)


chr11: 46385382
MDK
Exon (ENST00000433765.3/ENST00000433765.3, exon 1 of 1)


chr11: 46385392
MDK
Exon (ENST00000433765.3/ENST00000433765.3, exon 1 of 1)


chr11: 46385401
MDK
Exon (ENST00000433765.3/ENST00000433765.3, exon 1 of 1)


chr11: 46385413
MDK
Exon (ENST00000433765.3/ENST00000433765.3, exon 1 of 1)


chr11: 46385417
MDK
Exon (ENST00000433765.3/ENST00000433765.3, exon 1 of 1)


chr11: 46385418
MDK
Exon (ENST00000433765.3/ENST00000433765.3, exon 1 of 1)


chr11: 46385426
MDK
Exon (ENST00000433765.3/ENST00000433765.3, exon 1 of 1)


chr11: 46385427
MDK
Exon (ENST00000433765.3/ENST00000433765.3, exon 1 of 1)


chr11: 46385435
MDK
Exon (ENST00000433765.3/ENST00000433765.3, exon 1 of 1)


chr11: 46385442
MDK
Exon (ENST00000433765.3/ENST00000433765.3, exon 1 of 1)


chr11: 46385449
MDK
Exon (ENST00000433765.3/ENST00000433765.3, exon 1 of 1)


chr11: 46385456
MDK
Exon (ENST00000433765.3/ENST00000433765.3, exon 1 of 1)


chr11: 59565879
MIR3162
Exon (ENST00000661408.1/ENST00000661408.1, exon 1 of 8)


chr11: 59565903
MIR3162
Exon (ENST00000661408.1/ENST00000661408.1, exon 1 of 8)


chr11: 59565904
MIR3162
Exon (ENST00000661408.1/ENST00000661408.1, exon 1 of 8)


chr11: 59565907
MIR3162
Exon (ENST00000661408.1/ENST00000661408.1, exon 1 of 8)


chr11: 59565908
MIR3162
Exon (ENST00000661408.1/ENST00000661408.1, exon 1 of 8)


chr11: 59565910
MIR3162
Exon (ENST00000661408.1/ENST00000661408.1, exon 1 of 8)


chr11: 59565911
MIR3162
Exon (ENST00000661408.1/ENST00000661408.1, exon 1 of 8)


chr11: 59565914
MIR3162
Exon (ENST00000661408.1/ENST00000661408.1, exon 1 of 8)


chr11: 59565915
MIR3162
Exon (ENST00000661408.1/ENST00000661408.1, exon 1 of 8)


chr11: 59565921
MIR3162
Exon (ENST00000661408.1/ENST00000661408.1, exon 1 of 8)


chr11: 59565974
MIR3162
Exon (ENST00000661408.1/ENST00000661408.1, exon 1 of 8)


chr11: 59565976
MIR3162
Exon (ENST00000661408.1/ENST00000661408.1, exon 1 of 8)


chr11: 59565991
MIR3162
Exon (ENST00000661408.1/ENST00000661408.1, exon 1 of 8)


chr11: 59565997
MIR3162
Exon (ENST00000661408.1/ENST00000661408.1, exon 1 of 8)


chr11: 59566000
MIR3162
Exon (ENST00000661408.1/ENST00000661408.1, exon 1 of 8)


chr11: 59566007
MIR3162
Exon (ENST00000661408.1/ENST00000661408.1, exon 1 of 8)


chr11: 59566091
MIR3162
Exon (ENST00000661408.1/ENST00000661408.1, exon 1 of 8)


chr11: 60852858
PTGDR2
Exon (ENST00000332539.5/11251, exon 2 of 2)


chr11: 60852859
PTGDR2
Exon (ENST00000332539.5/11251, exon 2 of 2)


chr11: 60852871
PTGDR2
Exon (ENST00000332539.5/11251, exon 2 of 2)


chr11: 60852873
PTGDR2
Exon (ENST00000332539.5/11251, exon 2 of 2)


chr11: 60852884
PTGDR2
Exon (ENST00000332539.5/11251, exon 2 of 2)


chr11: 60852888
PTGDR2
Exon (ENST00000332539.5/11251, exon 2 of 2)


chr11: 60852903
PTGDR2
Exon (ENST00000332539.5/11251, exon 2 of 2)


chr11: 60852907
PTGDR2
Exon (ENST00000332539.5/11251, exon 2 of 2)


chr11: 60852911
PTGDR2
Exon (ENST00000332539.5/11251, exon 2 of 2)


chr11: 60852913
PTGDR2
Exon (ENST00000332539.5/11251, exon 2 of 2)


chr11: 64081931
FLRT1
Exon (ENST00000544948.1/ENST00000544948.1, exon 1 of 3)


chr11: 64081938
FLRT1
Exon (ENST00000544948.1/ENST00000544948.1, exon 1 of 3)


chr11: 64081940
FLRT1
Exon (ENST00000544948.1/ENST00000544948.1, exon 1 of 3)


chr11: 64082013
FLRT1
Exon (ENST00000544948.1/ENST00000544948.1, exon 1 of 3)


chr11: 64082017
FLRT1
Exon (ENST00000544948.1/ENST00000544948.1, exon 1 of 3)


chr11: 64082026
FLRT1
Exon (ENST00000544948.1/ENST00000544948.1, exon 1 of 3)


chr11: 64082135
FLRT1
Intron (ENST00000545464.5/28992, intron 3 of 3)


chr11: 64082193
FLRT1
Intron (ENST00000545464.5/28992, intron 3 of 3)


chr11: 64082195
FLRT1
Intron (ENST00000545464.5/28992, intron 3 of 3)


chr11: 64353134
CCDC88B
Promoter (<=1kb)


chr11: 64353136
CCDC88B
Promoter (<=1kb)


chr11: 64353151
CCDC88B
Promoter (<=1kb)


chr11: 64353185
CCDC88B
Promoter (<=1kb)


chr11: 64353187
CCDC88B
Promoter (<=1kb)


chr11: 64353214
CCDC88B
Promoter (<=1kb)


chr11: 65551191
LTBP3
Promoter (<=1kb)


chr11: 65551199
LTBP3
Promoter (<=1kb)


chr11: 65551205
LTBP3
Promoter (<=1kb)


chr11: 65551212
LTBP3
Promoter (<=1kb)


chr11: 66316102
CD248
Promoter (<=1kb)


chr11: 66316103
CD248
Promoter (<=1kb)


chr11: 66316126
CD248
Promoter (<=1kb)


chr11: 68039070
TCIRG1
Promoter (<=1kb)


chr11: 68039077
TCIRG1
Promoter (<=1kb)


chr11: 68039092
TCIRG1
Promoter (<=1kb)


chr11: 68039098
TCIRG1
Promoter (<=1kb)


chr11: 68039100
TCIRG1
Promoter (<=1kb)


chr11: 68039144
TCIRG1
Promoter (<=1kb)


chr11: 68946886
IGHMBP2
Distal Intergenic


chr11: 68946898
IGHMBP2
Distal Intergenic


chr11: 69654991
CCND1
Intron (ENST00000542515.5/ENST00000542515.5, intron 1 of 2)


chr11: 69655008
CCND1
Intron (ENST00000542515.5/ENST00000542515.5, intron 1 of 2)


chr11: 69655050
CCND1
Intron (ENST00000542515.5/ENST00000542515.5, intron 1 of 2)


chr11: 69655053
CCND1
Intron (ENST00000542515.5/ENST00000542515.5, intron 1 of 2)


chr11: 72106024
LRTOMT
Promoter (<=1kb)


chr11: 72106036
LRTOMT
Promoter (<=1kb)


chr11: 72106040
LRTOMT
Promoter (<=1kb)


chr11: 72106051
LRTOMT
Promoter (<=1kb)


chr11: 72106087
LRTOMT
Promoter (<=1kb)


chr11: 72106094
LRTOMT
Promoter (<=1kb)


chr11: 72106108
LRTOMT
Promoter (<=1kb)


chr11: 76292339
THAP12
Distal Intergenic


chr11: 76292340
THAP12
Distal Intergenic


chr11: 76292356
THAP12
Distal Intergenic


chr11: 76292368
THAP12
Distal Intergenic


chr11: 76292392
THAP12
Distal Intergenic


chr11: 76292393
THAP12
Distal Intergenic


chr11: 76292397
THAP12
Distal Intergenic


chr11: 76292398
THAP12
Distal Intergenic


chr11: 95151013
LOC101929295
Promoter (<=1kb)


chr11: 95151031
LOC101929295
Promoter (<=1kb)


chr11: 95151034
LOC101929295
Promoter (<=1kb)


chr11: 95232446
SESN3
Promoter (<=1kb)


chr11: 95232447
SESN3
Promoter (<=1kb)


chr11: 117820155
DSCAML1
Promoter (2-3kb)


chr11: 117820165
DSCAML1
Promoter (2-3kb)


chr11: 125099290
TMEM218
Intron (ENST00000531909.5/219854, intron 4 of 4)


chr11: 125099307
TMEM218
Intron (ENST00000531909.5/219854, intron 4 of 4)


chr11: 125099311
TMEM218
Intron (ENST00000531909.5/219854, intron 4 of 4)


chr11: 125099316
TMEM218
Intron (ENST00000531909.5/219854, intron 4 of 4)


chr11: 128860025
KCNJ1
Intron (ENST00000392665.6/3758, intron 1 of 1)


chr11: 128860035
KCNJ1
Intron (ENST00000392665.6/3758, intron 1 of 1)


chr11: 128860042
KCNJ1
Intron (ENST00000392665.6/3758, intron 1 of 1)


chr11: 128860066
KCNJ1
Intron (ENST00000392665.6/3758, intron 1 of 1)


chr11: 129316134
ARHGAP32
Distal Intergenic


chr11: 129316137
ARHGAP32
Distal Intergenic


chr11: 130179878
ST14
Intron (ENST00000278742.6/6768, intron 1 of 18)


chr11: 130179900
ST14
Intron (ENST00000278742.6/6768, intron 1 of 18)


chr11: 130209380
ST14
Intron (ENST00000278742.6/6768, intron 17 of 18)


chr11: 130209385
ST14
Intron (ENST00000278742.6/6768, intron 17 of 18)


chr11: 130209392
ST14
Intron (ENST00000278742.6/6768, intron 17 of 18)


chr12: 1796632
CACNA2D4
Promoter (<=1kb)


chr12: 1796634
CACNA2D4
Promoter (<=1kb)


chr12: 1796641
CACNA2D4
Promoter (<=1kb)


chr12: 1796644
CACNA2D4
Promoter (<=1kb)


chr12: 1796646
CACNA2D4
Promoter (<=1kb)


chr12: 1796674
CACNA2D4
Promoter (<=1kb)


chr12: 3244606
TSPAN9
Intron (ENST00000649909.1/10867, intron 2 of 6)


chr12: 3244622
TSPAN9
Intron (ENST00000649909.1/10867, intron 2 of 6)


chr12: 3244626
TSPAN9
Intron (ENST00000649909.1/10867, intron 2 of 6)


chr12: 7291172
ACSM4
Distal Intergenic


chr12: 7291173
ACSM4
Distal Intergenic


chr12: 7440396
CD163L1
Intron (ENST00000313599.7/283316, intron 2 of 19)


chr12: 7440398
CD163L1
Intron (ENST00000313599.7/283316, intron 2 of 19)


chr12: 7440401
CD163L1
Intron (ENST00000313599.7/283316, intron 2 of 19)


chr12: 7440403
CD163L1
Intron (ENST00000313599.7/283316, intron 2 of 19)


chr12: 21941433
ABCC9
Promoter (<=1kb)


chr12: 21941437
ABCC9
Promoter (<=1kb)


chr12: 21941620
ABCC9
Promoter (<=1kb)


chr12: 21941630
ABCC9
Promoter (<=1kb)


chr12: 21941645
ABCC9
Promoter (<=1kb)


chr12: 21942141
ABCC9
Promoter (<=1kb)


chr12: 21942148
ABCC9
Promoter (<=1kb)


chr12: 21942161
ABCC9
Promoter (<=1kb)


chr12: 21942178
ABCC9
Promoter (<=1kb)


chr12: 43551605
ADAMTS20
Promoter (<=1kb)


chr12: 43551611
ADAMTS20
Promoter (<=1kb)


chr12: 43551614
ADAMTS20
Promoter (<=1kb)


chr12: 43551633
ADAMTS20
Promoter (<=1kb)


chr12: 43551638
ADAMTS20
Promoter (<=1kb)


chr12: 43551647
ADAMTS20
Promoter (<=1kb)


chr12: 43551649
ADAMTS20
Promoter (<=1kb)


chr12: 43551651
ADAMTS20
Promoter (<=1kb)


chr12: 43551653
ADAMTS20
Promoter (<=1kb)


chr12: 51721659
SCN8A
Exon (ENST00000667214.1/6334, exon 12 of 12)


chr12: 51721661
SCN8A
Exon (ENST00000667214.1/6334, exon 12 of 12)


chr12: 51721668
SCN8A
Exon (ENST00000667214.1/6334, exon 12 of 12)


chr12: 51721679
SCN8A
Exon (ENST00000667214.1/6334, exon 12 of 12)


chr12: 53938984
HOXC13
Promoter (<=1kb)


chr12: 53938990
HOXC13
Promoter (<=1kb)


chr12: 53939015
HOXC13
Promoter (<=1kb)


chr12: 53939117
HOXC13
Promoter (<=1kb)


chr12: 53973676
HOXC11
Promoter (<=1kb)


chr12: 53973713
HOXC11
Promoter (<=1kb)


chr12: 53973722
HOXC11
Promoter (<=1kb)


chr12: 53974254
HOTAIR
Promoter (<=1kb)


chr12: 54000568
HOXC9
Promoter (<=1kb)


chr12: 54000569
HOXC9
Promoter (<=1kb)


chr12: 54000570
HOXC9
Promoter (<=1kb)


chr12: 54000571
HOXC9
Promoter (<=1kb)


chr12: 54000572
HOXC9
Promoter (<=1kb)


chr12: 54000578
HOXC9
Promoter (<=1kb)


chr12: 54000579
HOXC9
Promoter (<=1kb)


chr12: 54000644
HOXC9
Promoter (<=1kb)


chr12: 54000645
HOXC9
Promoter (<=1kb)


chr12: 54000649
HOXC9
Promoter (<=1kb)


chr12: 54000650
HOXC9
Promoter (<=1kb)


chr12: 57627715
B4GALNT1
Promoter (1-2kb)


chr12: 57627733
B4GALNT1
Promoter (<=1kb)


chr12: 57627751
B4GALNT1
Promoter (<=1kb)


chr12: 57627753
B4GALNT1
Promoter (<=1kb)


chr12: 57627840
B4GALNT1
Promoter (<=1kb)


chr12: 57627842
B4GALNT1
Promoter (<=1kb)


chr12: 57627847
B4GALNT1
Promoter (<=1kb)


chr12: 57627849
B4GALNT1
Promoter (<=1kb)


chr12: 57865324
LOC283387
Distal Intergenic


chr12: 57865340
LOC283387
Distal Intergenic


chr12: 57865341
LOC283387
Distal Intergenic


chr12: 57865349
LOC283387
Distal Intergenic


chr12: 57865350
LOC283387
Distal Intergenic


chr12: 57865356
LOC283387
Distal Intergenic


chr12: 57865357
LOC283387
Distal Intergenic


chr12: 57865460
LOC283387
Distal Intergenic


chr12: 57865461
LOC283387
Distal Intergenic


chr12: 57865466
LOC283387
Distal Intergenic


chr12: 57865467
LOC283387
Distal Intergenic


chr12: 57865472
LOC283387
Distal Intergenic


chr12: 57865473
LOC283387
Distal Intergenic


chr12: 57865484
LOC283387
Distal Intergenic


chr12: 57865485
LOC283387
Distal Intergenic


chr12: 57865486
LOC283387
Distal Intergenic


chr12: 57865487
LOC283387
Distal Intergenic


chr12: 57865491
LOC283387
Distal Intergenic


chr12: 57865492
LOC283387
Distal Intergenic


chr12: 57865493
LOC283387
Distal Intergenic


chr12: 57865494
LOC283387
Distal Intergenic


chr12: 57865498
LOC283387
Distal Intergenic


chr12: 57865499
LOC283387
Distal Intergenic


chr12: 57865541
LOC283387
Distal Intergenic


chr12: 57865543
LOC283387
Distal Intergenic


chr12: 57865547
LOC283387
Distal Intergenic


chr12: 57865569
LOC283387
Distal Intergenic


chr12: 57865575
LOC283387
Distal Intergenic


chr12: 57865588
LOC283387
Distal Intergenic


chr12: 57865589
LOC283387
Distal Intergenic


chr12: 62631991
LINC01465
Distal Intergenic


chr12: 62632007
LINC01465
Distal Intergenic


chr12: 62632008
LINC01465
Distal Intergenic


chr12: 62632010
LINC01465
Distal Intergenic


chr12: 62632011
LINC01465
Distal Intergenic


chr12: 110688833
HVCN1
Promoter (<=1kb)


chr12: 110688840
HVCN1
Promoter (<=1kb)


chr12: 110688842
HVCN1
Promoter (<=1kb)


chr12: 110688873
HVCN1
Promoter (<=1kb)


chr12: 110688890
HVCN1
Promoter (<=1kb)


chr12: 110688894
HVCN1
Promoter (<=1kb)


chr12: 110688896
HVCN1
Promoter (<=1kb)


chr12: 110688905
HVCN1
Promoter (<=1kb)


chr12: 110688914
HVCN1
Promoter (<=1kb)


chr12: 110688924
HVCN1
Promoter (<=1kb)


chr12: 110689040
HVCN1
Promoter (<=1kb)


chr12: 110689047
HVCN1
Promoter (<=1kb)


chr12: 110689054
HVCN1
Promoter (<=1kb)


chr12: 110689061
HVCN1
Promoter (<=1kb)


chr12: 110689084
HVCN1
Promoter (<=1kb)


chr12: 110689093
HVCN1
Promoter (<=1kb)


chr12: 110689094
HVCN1
Promoter (<=1kb)


chr12: 110689097
HVCN1
Promoter (<=1kb)


chr12: 110689098
HVCN1
Promoter (<=1kb)


chr12: 110689099
HVCN1
Promoter (<=1kb)


chr12: 110689100
HVCN1
Promoter (<=1kb)


chr12: 110689106
HVCN1
Promoter (<=1kb)


chr12: 110689107
HVCN1
Promoter (<=1kb)


chr12: 110689111
HVCN1
Promoter (<=1kb)


chr12: 110689112
HVCN1
Promoter (<=1kb)


chr12: 110689187
HVCN1
Promoter (<=1kb)


chr12: 110689193
HVCN1
Promoter (<=1kb)


chr12: 110689199
HVCN1
Promoter (<=1kb)


chr12: 110689205
HVCN1
Promoter (<=1kb)


chr12: 110689218
HVCN1
Promoter (<=1kb)


chr12: 116698253
C12orf49
Distal Intergenic


chr12: 116698254
C12orf49
Distal Intergenic


chr12: 116698256
C12orf49
Distal Intergenic


chr12: 116698257
C12orf49
Distal Intergenic


chr12: 116698277
C12orf49
Distal Intergenic


chr12: 116698278
C12orf49
Distal Intergenic


chr12: 118131915
VSIG10
Intron (ENST00000542011.1/54621, intron 2 of 3)


chr12: 118131927
VSIG10
Intron (ENST00000542011.1/54621, intron 2 of 3)


chr12: 121227419
P2RX4
Intron (ENST00000538701.5/5025, intron 1 of 3)


chr12: 121227431
P2RX4
Intron (ENST00000538701.5/5025, intron 1 of 3)


chr12: 130163471
FZD10
Promoter (1-2kb)


chr12: 130163473
FZD10
Promoter (1-2kb)


chr12: 132904798
CHFR
Promoter (<=1kb)


chr12: 132904799
CHFR
Promoter (<=1kb)


chr12: 132904804
CHFR
Promoter (<=1kb)


chr12: 132904805
CHFR
Promoter (<=1kb)


chr12: 132904807
CHFR
Promoter (<=1kb)


chr13: 78595986
LOC780529
Promoter (<=1kb)


chr13: 78596001
LOC780529
Promoter (<=1kb)


chr13: 78596003
LOC780529
Promoter (<=1kb)


chr13: 78596011
LOC780529
Promoter (<=1kb)


chr13: 78596024
LOC780529
Promoter (<=1kb)


chr13: 78596050
LOC780529
Promoter (<=1kb)


chr13: 78596058
LOC780529
Promoter (<=1kb)


chr13: 78596069
LOC780529
Promoter (<=1kb)


chr13: 78596078
LOC780529
Promoter (<=1kb)


chr13: 78596080
LOC780529
Promoter (<=1kb)


chr13: 78596104
LOC780529
Promoter (<=1kb)


chr13: 78596109
LOC780529
Promoter (<=1kb)


chr13: 78596115
LOC780529
Promoter (<=1kb)


chr13: 78596129
LOC780529
Promoter (<=1kb)


chr13: 78596133
LOC780529
Promoter (<=1kb)


chr13: 78596135
LOC780529
Promoter (<=1kb)


chr13: 78596137
LOC780529
Promoter (<=1kb)


chr13: 78596232
LOC780529
Promoter (<=1kb)


chr13: 78596236
LOC780529
Promoter (<=1kb)


chr13: 78596244
LOC780529
Promoter (<=1kb)


chr13: 78596250
LOC780529
Promoter (<=1kb)


chr13: 109400373
LINC00399
Promoter (<=1kb)


chr13: 109400374
LINC00399
Promoter (<=1kb)


chr13: 109400375
LINC00399
Promoter (<=1kb)


chr13: 109400376
LINC00399
Promoter (<=1kb)


chr13: 112104494
SOX1-OT
Promoter (2-3kb)


chr13: 112104508
SOX1-OT
Promoter (2-3kb)


chr13: 112104673
SOX1-OT
Promoter (2-3kb)


chr13: 112104683
SOX1-OT
Promoter (2-3kb)


chr13: 112104685
SOX1-OT
Promoter (2-3kb)


chr13: 112104691
SOX1-OT
Promoter (2-3kb)


chr13: 112104700
SOX1-OT
Promoter (2-3kb)


chr13: 112104721
SOX1-OT
Promoter (2-3kb)


chr13: 112104725
SOX1-OT
Promoter (2-3kb)


chr13: 112104727
SOX1-OT
Promoter (2-3kb)


chr13: 112104782
SOX1-OT
Promoter (2-3kb)


chr13: 112104788
SOX1-OT
Promoter (2-3kb)


chr13: 112104794
SOX1-OT
Promoter (2-3kb)


chr13: 112104799
SOX1-OT
Promoter (2-3kb)


chr13: 112104811
SOX1-OT
Promoter (2-3kb)


chr13: 112888853
MCF2L
Distal Intergenic


chr13: 112888855
MCF2L
Distal Intergenic


chr13: 112888866
MCF2L
Distal Intergenic


chr13: 112888875
MCF2L
Distal Intergenic


chr13: 113549498
TMCO3
Promoter (1-2kb)


chr13: 113549524
TMCO3
Promoter (1-2kb)


chr13: 113549544
TMCO3
Promoter (1-2kb)


chr13: 113549558
TMCO3
Promoter (1-2kb)


chr14: 23576274
JPH4
Promoter (1-2kb)


chr14: 23576292
JPH4
Promoter (1-2kb)


chr14: 23576360
JPH4
Promoter (1-2kb)


chr14: 23576365
JPH4
Promoter (1-2kb)


chr14: 23576369
JPH4
Promoter (1-2kb)


chr14: 23576380
JPH4
Promoter (1-2kb)


chr14: 23576406
JPH4
Promoter (1-2kb)


chr14: 36508416
SFTA3
Intron (ENST00000634305.1/ENST00000634305.1, intron 3 of 3)


chr14: 36508418
SFTA3
Intron (ENST00000634305.1/ENST00000634305.1, intron 3 of 3)


chr14: 36508424
SFTA3
Intron (ENST00000634305.1/ENST00000634305.1, intron 3 of 3)


chr14: 36508426
SFTA3
Intron (ENST00000634305.1/ENST00000634305.1, intron 3 of 3)


chr14: 36508431
SFTA3
Intron (ENST00000634305.1/ENST00000634305.1, intron 3 of 3)


chr14: 36508435
SFTA3
Intron (ENST00000634305.1/ENST00000634305.1, intron 3 of 3)


chr14: 36508442
SFTA3
Intron (ENST00000634305.1/ENST00000634305.1, intron 3 of 3)


chr14: 36508448
SFTA3
Intron (ENST00000634305.1/ENST00000634305.1, intron 3 of 3)


chr14: 37588224
FOXA1
Downstream (1-2kb)


chr14: 37588225
FOXA1
Downstream (1-2kb)


chr14: 37588226
FOXA1
Downstream (1-2kb)


chr14: 37588227
FOXA1
Downstream (1-2kb)


chr14: 37588233
FOXA1
Downstream (1-2kb)


chr14: 37588234
FOXA1
Downstream (1-2kb)


chr14: 37588235
FOXA1
Downstream (1-2kb)


chr14: 37588240
FOXA1
Downstream (1-2kb)


chr14: 37588248
FOXA1
Downstream (1-2kb)


chr14: 64038597
SYNE2
Intron (ENST00000358025.7/23224, intron 45 of 115)


chr14: 64038605
SYNE2
Intron (ENST00000358025.7/23224, intron 45 of 115)


chr14: 64038606
SYNE2
Intron (ENST00000358025.7/23224, intron 45 of 115)


chr14: 64038623
SYNE2
Intron (ENST00000358025.7/23224, intron 45 of 115)


chr14: 64038624
SYNE2
Intron (ENST00000358025.7/23224, intron 45 of 115)


chr14: 64038626
SYNE2
Intron (ENST00000358025.7/23224, intron 45 of 115)


chr14: 64038650
SYNE2
Intron (ENST00000358025.7/23224, intron 45 of 115)


chr14: 76961840
LINC01629
Promoter (2-3kb)


chr14: 76961853
LINC01629
Promoter (2-3kb)


chr14: 76961867
LINC01629
Promoter (2-3kb)


chr14: 76961872
LINC01629
Promoter (2-3kb)


chr14: 76961883
LINC01629
Promoter (2-3kb)


chr14: 76961884
LINC01629
Promoter (2-3kb)


chr14: 76961885
LINC01629
Promoter (2-3kb)


chr14: 76961886
LINC01629
Promoter (2-3kb)


chr14: 76961993
LINC01629
Promoter (2-3kb)


chr14: 76961999
LINC01629
Promoter (2-3kb)


chr14: 76962008
LINC01629
Promoter (2-3kb)


chr14: 76962016
LINC01629
Promoter (2-3kb)


chr14: 76962031
LINC01629
Promoter (2-3kb)


chr14: 77125128
TMEM63C
Intron (ENST00000557752.1/57156, intron 2 of 5)


chr14: 77125135
TMEM63C
Intron (ENST00000557752.1/57156, intron 2 of 5)


chr14: 77125139
TMEM63C
Intron (ENST00000557752.1/57156, intron 2 of 5)


chr14: 77125141
TMEM63C
Intron (ENST00000557752.1/57156, intron 2 of 5)


chr14: 77125151
TMEM63C
Intron (ENST00000557752.1/57156, intron 2 of 5)


chr14: 77125210
TMEM63C
Intron (ENST00000557752.1/57156, intron 2 of 5)


chr14: 77125215
TMEM63C
Intron (ENST00000557752.1/57156, intron 2 of 5)


chr14: 77125217
TMEM63C
Intron (ENST00000557752.1/57156, intron 2 of 5)


chr14: 77125231
TMEM63C
Intron (ENST00000557752.1/57156, intron 2 of 5)


chr14: 77125283
TMEM63C
Intron (ENST00000557752.1/57156, intron 2 of 5)


chr14: 77125289
TMEM63C
Intron (ENST00000557752.1/57156, intron 2 of 5)


chr14: 77125313
TMEM63C
Intron (ENST00000557752.1/57156, intron 2 of 5)


chr14: 77125354
TMEM63C
Intron (ENST00000557752.1/57156, intron 2 of 5)


chr14: 77125355
TMEM63C
Intron (ENST00000557752.1/57156, intron 2 of 5)


chr14: 77125361
TMEM63C
Intron (ENST00000557752.1/57156, intron 2 of 5)


chr14: 77125386
TMEM63C
Intron (ENST00000557752.1/57156, intron 2 of 5)


chr14: 77125392
TMEM63C
Intron (ENST00000557752.1/57156, intron 2 of 5)


chr14: 77125394
TMEM63C
Intron (ENST00000557752.1/57156, intron 2 of 5)


chr14: 77125395
TMEM63C
Intron (ENST00000557752.1/57156, intron 2 of 5)


chr14: 77125401
TMEM63C
Intron (ENST00000557752.1/57156, intron 2 of 5)


chr14: 77125402
TMEM63C
Intron (ENST00000557752.1/57156, intron 2 of 5)


chr14: 90600763
TTC7B
Intron (ENST00000328459.11/145567, intron 17 of 19)


chr14: 90600771
TTC7B
Intron (ENST00000328459.11/145567, intron 17 of 19)


chr14: 90600800
TTC7B
Intron (ENST00000328459.11/145567, intron 17 of 19)


chr14: 90600805
TTC7B
Intron (ENST00000328459.11/145567, intron 17 of 19)


chr14: 90600821
TTC7B
Intron (ENST00000328459.11/145567, intron 17 of 19)


chr14: 90828164
TTC7B
Exon (ENST00000659138.1/ENST00000659138.1, exon 1 of 4)


chr14: 90828166
TTC7B
Exon (ENST00000659138.1/ENST00000659138.1, exon 1 of 4)


chr14: 90828180
TTC7B
Exon (ENST00000659138.1/ENST00000659138.1, exon 1 of 4)


chr14: 90828184
TTC7B
Exon (ENST00000659138.1/ENST00000659138.1, exon 1 of 4)


chr14: 90828189
TTC7B
Exon (ENST00000659138.1/ENST00000659138.1, exon 1 of 4)


chr14: 90828194
TTC7B
Exon (ENST00000659138.1/ENST00000659138.1, exon 1 of 4)


chr14: 90828202
TTC7B
Distal Intergenic


chr14: 90828204
TTC7B
Distal Intergenic


chr14: 90828207
TTC7B
Distal Intergenic


chr14: 95460840
SYNE3
Intron (ENST00000557275.5/161176, intron 3 of 16)


chr14: 95460842
SYNE3
Intron (ENST00000557275.5/161176, intron 3 of 16)


chr14: 95460890
SYNE3
Intron (ENST00000557275.5/161176, intron 3 of 16)


chr14: 99737735
EML1
Promoter (<=1kb)


chr14: 99737737
EML1
Promoter (<=1kb)


chr14: 99737774
EML1
Promoter (<=1kb)


chr14: 100654824
LINC00523
Promoter (2-3kb)


chr14: 100654836
LINC00523
Promoter (2-3kb)


chr14: 100654840
LINC00523
Promoter (2-3kb)


chr14: 103879905
LINC00637
Exon (ENST00000660176.1/ENST00000660176.1, exon 2 of 2)


chr14: 103879920
LINC00637
Exon (ENST00000660176.1/ENST00000660176.1, exon 2 of 2)


chr14: 103879970
LINC00637
Exon (ENST00000660176.1/ENST00000660176.1, exon 2 of 2)


chr14: 103879986
LINC00637
Exon (ENST00000660176.1/ENST00000660176.1, exon 2 of 2)


chr14: 103880033
LINC00637
Exon (ENST00000660176.1/ENST00000660176.1, exon 2 of 2)


chr14: 104367967
LINC02691
Distal Intergenic


chr14: 104367968
LINC02691
Distal Intergenic


chr14: 104367969
LINC02691
Distal Intergenic


chr14: 104367970
LINC02691
Distal Intergenic


chr14: 104367972
LINC02691
Distal Intergenic


chr14: 104367973
LINC02691
Distal Intergenic


chr14: 104367994
LINC02691
Distal Intergenic


chr14: 104367995
LINC02691
Distal Intergenic


chr14: 104367996
LINC02691
Distal Intergenic


chr14: 104367997
LINC02691
Distal Intergenic


chr14: 104368028
LINC02691
Distal Intergenic


chr14: 104368033
LINC02691
Distal Intergenic


chr14: 104368089
LINC02691
Distal Intergenic


chr14: 104368099
LINC02691
Distal Intergenic


chr14: 105196737
NUDT14
Distal Intergenic


chr14: 105196741
NUDT14
Distal Intergenic


chr14: 105196743
NUDT14
Distal Intergenic


chr14: 105196756
NUDT14
Distal Intergenic


chr14: 105196757
NUDT14
Distal Intergenic


chr14: 105196767
NUDT14
Distal Intergenic


chr14: 105196768
NUDT14
Distal Intergenic


chr14: 105196769
NUDT14
Distal Intergenic


chr14: 105196770
NUDT14
Distal Intergenic


chr14: 105196788
NUDT14
Distal Intergenic


chr14: 105196790
NUDT14
Distal Intergenic


chr14: 105196793
NUDT14
Distal Intergenic


chr14: 105196903
NUDT14
Distal Intergenic


chr14: 105196917
NUDT14
Distal Intergenic


chr14: 105196918
NUDT14
Distal Intergenic


chr14: 105196923
NUDT14
Distal Intergenic


chr14: 105196924
NUDT14
Distal Intergenic


chr14: 105196928
NUDT14
Distal Intergenic


chr14: 105196929
NUDT14
Distal Intergenic


chr14: 105196953
NUDT14
Distal Intergenic


chr15: 67835522
SKOR1
Promoter (2-3kb)


chr15: 67835527
SKOR1
Promoter (2-3kb)


chr15: 67835540
SKOR1
Promoter (2-3kb)


chr15: 67835550
SKOR1
Promoter (2-3kb)


chr15: 67835558
SKOR1
Promoter (2-3kb)


chr15: 67835608
SKOR1
Promoter (2-3kb)


chr15: 76347141
SCAPER
Downstream (<1kb)


chr15: 76347145
SCAPER
Downstream (<1kb)


chr15: 76347154
SCAPER
Downstream (<1kb)


chr15: 76347156
SCAPER
Downstream (<1kb)


chr15: 76347166
SCAPER
Downstream (<1kb)


chr15: 76347263
SCAPER
Downstream (<1kb)


chr15: 76347265
SCAPER
Downstream (<1kb)


chr15: 76347272
SCAPER
Downstream (<1kb)


chr15: 76347291
SCAPER
Downstream (<1kb)


chr15: 89407577
MIR9-3HG
Distal Intergenic


chr15: 89407579
MIR9-3HG
Distal Intergenic


chr15: 89407583
MIR9-3HG
Distal Intergenic


chr15: 89408147
MIR9-3HG
Distal Intergenic


chr15: 89408149
MIR9-3HG
Distal Intergenic


chr15: 89408158
MIR9-3HG
Distal Intergenic


chr15: 89408160
MIR9-3HG
Distal Intergenic


chr15: 89408170
MIR9-3HG
Distal Intergenic


chr15: 89408173
MIR9-3HG
Distal Intergenic


chr15: 89408185
MIR9-3HG
Distal Intergenic


chr16: 64422
RHBDF1
Promoter (<=1kb)


chr16: 64426
RHBDF1
Promoter (<=1kb)


chr16: 1679822
JPT2
Promoter (<=1kb)


chr16: 1679838
JPT2
Promoter (<=1kb)


chr16: 2224654
E4F1
Promoter (<=1kb)


chr16: 2224662
E4F1
Promoter (<=1kb)


chr16: 2224666
E4F1
Promoter (<=1kb)


chr16: 2224689
E4F1
Promoter (<=1kb)


chr16: 2603395
LOC652276
Promoter (<=1kb)


chr16: 2603404
LOC652276
Promoter (<=1kb)


chr16: 2603405
LOC652276
Promoter (<=1kb)


chr16: 2603414
LOC652276
Promoter (<=1kb)


chr16: 2603444
LOC652276
Promoter (<=1kb)


chr16: 2603476
LOC652276
Promoter (<=1kb)


chr16: 2603622
LOC652276
Promoter (<=1kb)


chr16: 2603625
LOC652276
Promoter (<=1kb)


chr16: 2603654
LOC652276
Promoter (<=1kb)


chr16: 2603657
LOC652276
Promoter (<=1kb)


chr16: 2603673
LOC652276
Promoter (<=1kb)


chr16: 2603704
LOC652276
Promoter (<=1kb)


chr16: 4893573
PPL
Promoter (<=1kb)


chr16: 4893574
PPL
Promoter (<=1kb)


chr16: 4893584
PPL
Promoter (<=1kb)


chr16: 4893585
PPL
Promoter (<=1kb)


chr16: 4893588
PPL
Promoter (<=1kb)


chr16: 4893589
PPL
Promoter (<=1kb)


chr16: 4893613
PPL
Promoter (<=1kb)


chr16: 4893617
PPL
Promoter (<=1kb)


chr16: 25066728
LINC02175
Promoter (<=1kb)


chr16: 25066736
LINC02175
Promoter (<=1kb)


chr16: 25066739
LINC02175
Promoter (<=1kb)


chr16: 25066742
LINC02175
Promoter (<=1kb)


chr16: 30005475
DOC2A
Promoter (1-2kb)


chr16: 30005481
DOC2A
Promoter (1-2kb)


chr16: 30429550
DCTPP1
Promoter (<=1kb)


chr16: 30429572
DCTPP1
Promoter (<=1kb)


chr16: 30429585
DCTPP1
Promoter (<=1kb)


chr16: 30897175
CTF1
Promoter (<=1kb)


chr16: 30897178
CTF1
Promoter (<=1kb)


chr16: 30897179
CTF1
Promoter (<=1kb)


chr16: 30897180
CTF1
Promoter (<=1kb)


chr16: 30897181
CTF1
Promoter (<=1kb)


chr16: 30897182
CTF1
Promoter (<=1kb)


chr16: 30897183
CTF1
Promoter (<=1kb)


chr16: 30897189
CTF1
Promoter (<=1kb)


chr16: 30897190
CTF1
Promoter (<=1kb)


chr16: 51134634
SALL1
Downstream (1-2kb)


chr16: 51134643
SALL1
Downstream (1-2kb)


chr16: 51134645
SALL1
Downstream (1-2kb)


chr16: 51134732
SALL1
Downstream (1-2kb)


chr16: 51134734
SALL1
Downstream (1-2kb)


chr16: 69965499
CLEC18A
Distal Intergenic


chr16: 69965517
CLEC18A
Distal Intergenic


chr16: 69965522
CLEC18A
Distal Intergenic


chr16: 69965526
CLEC18A
Distal Intergenic


chr16: 69965531
CLEC18A
Distal Intergenic


chr16: 73063101
ZFHX3
Intron (ENST00000641206.2/463, intron 8 of 17)


chr16: 73063102
ZFHX3
Intron (ENST00000641206.2/463, intron 8 of 17)


chr16: 73063116
ZFHX3
Intron (ENST00000641206.2/463, intron 8 of 17)


chr16: 73063117
ZFHX3
Intron (ENST00000641206.2/463, intron 8 of 17)


chr16: 73063119
ZFHX3
Intron (ENST00000641206.2/463, intron 8 of 17)


chr16: 73063121
ZFHX3
Intron (ENST00000641206.2/463, intron 8 of 17)


chr16: 73063139
ZFHX3
Intron (ENST00000641206.2/463, intron 8 of 17)


chr16: 74407173
CLEC18B
Downstream (1-2kb)


chr16: 74407175
CLEC18B
Downstream (1-2kb)


chr16: 74407181
CLEC18B
Downstream (1-2kb)


chr16: 74407183
CLEC18B
Downstream (1-2kb)


chr16: 74407190
CLEC18B
Downstream (1-2kb)


chr16: 81431801
CMIP
Distal Intergenic


chr16: 81431802
CMIP
Distal Intergenic


chr16: 81431809
CMIP
Distal Intergenic


chr16: 81431810
CMIP
Distal Intergenic


chr16: 81431822
CMIP
Distal Intergenic


chr16: 85690021
GINS2
Promoter (<=1kb)


chr16: 85690041
GINS2
Promoter (<=1kb)


chr16: 86578985
FOXL1
Promoter (<=1kb)


chr16: 86579015
FOXL1
Promoter (<=1kb)


chr16: 86579035
FOXL1
Promoter (<=1kb)


chr16: 86579395
FOXL1
Promoter (<=1kb)


chr16: 86579396
FOXL1
Promoter (<=1kb)


chr16: 86579410
FOXL1
Promoter (<=1kb)


chr16: 87706098
KLHDC4
Promoter (2-3kb)


chr16: 87706102
KLHDC4
Promoter (2-3kb)


chr16: 89657050
CHMP1A
Promoter (<=1kb)


chr16: 89657057
CHMP1A
Promoter (<=1kb)


chr16: 89657064
CHMP1A
Promoter (<=1kb)


chr16: 89657120
CHMP1A
Promoter (<=1kb)


chr17: 17836673
SREBF1
Promoter (<=1kb)


chr17: 17836684
SREBF1
Promoter (<=1kb)


chr17: 17836686
SREBF1
Promoter (<=1kb)


chr17: 17836695
SREBF1
Promoter (<=1kb)


chr17: 17836730
SREBF1
Promoter (<=1kb)


chr17: 17836797
SREBF1
Promoter (<=1kb)


chr17: 17836812
SREBF1
Promoter (<=1kb)


chr17: 44776152
ADAM11
Promoter (<=1kb)


chr17: 44776160
ADAM11
Promoter (<=1kb)


chr17: 44776166
ADAM11
Promoter (<=1kb)


chr17: 44776172
ADAM11
Promoter (<=1kb)


chr17: 44776178
ADAM11
Promoter (<=1kb)


chr17: 44776180
ADAM11
Promoter (<=1kb)


chr17: 44776221
ADAM11
Promoter (<=1kb)


chr17: 44776224
ADAM11
Promoter (<=1kb)


chr17: 44776243
ADAM11
Promoter (<=1kb)


chr17: 44776244
ADAM11
Promoter (<=1kb)


chr17: 44776264
ADAM11
Promoter (<=1kb)


chr17: 44776265
ADAM11
Promoter (<=1kb)


chr17: 45133276
PLCD3
Promoter (<=1kb)


chr17: 45133280
PLCD3
Promoter (<=1kb)


chr17: 45133282
PLCD3
Promoter (<=1kb)


chr17: 45133294
PLCD3
Promoter (<=1kb)


chr17: 45133308
PLCD3
Promoter (<=1kb)


chr17: 45133316
PLCD3
Promoter (<=1kb)


chr17: 48550618
HOXB-AS3
Promoter (<=1kb)


chr17: 48550634
HOXB-AS3
Promoter (1-2kb)


chr17: 48550638
HOXB-AS3
Promoter (1-2kb)


chr17: 48550649
HOXB-AS3
Promoter (1-2kb)


chr17: 48550653
HOXB-AS3
Promoter (1-2kb)


chr17: 48550661
HOXB-AS3
Promoter (1-2kb)


chr17: 48550676
HOXB-AS3
Promoter (1-2kb)


chr17: 48550681
HOXB-AS3
Promoter (1-2kb)


chr17: 48550684
HOXB-AS3
Promoter (1-2kb)


chr17: 48550869
HOXB-AS3
Promoter (1-2kb)


chr17: 48550912
HOXB-AS3
Promoter (1-2kb)


chr17: 48550941
HOXB-AS3
Promoter (1-2kb)


chr17: 48550942
HOXB-AS3
Promoter (1-2kb)


chr17: 48550945
HOXB-AS3
Promoter (1-2kb)


chr17: 48550946
HOXB-AS3
Promoter (1-2kb)


chr17: 48550978
HOXB-AS3
Promoter (1-2kb)


chr17: 48550981
HOXB-AS3
Promoter (1-2kb)


chr17: 48551037
HOXB-AS3
Promoter (1-2kb)


chr17: 48551039
HOXB-AS3
Promoter (1-2kb)


chr17: 48551043
HOXB-AS3
Promoter (1-2kb)


chr17: 48551049
HOXB-AS3
Promoter (1-2kb)


chr17: 48551052
HOXB-AS3
Promoter (1-2kb)


chr17: 48551056
HOXB-AS3
Promoter (1-2kb)


chr17: 48551058
HOXB-AS3
Promoter (1-2kb)


chr17: 48551062
HOXB-AS3
Promoter (1-2kb)


chr17: 48551070
HOXB-AS3
Promoter (1-2kb)


chr17: 48578036
HOXB4
Promoter (<=1kb)


chr17: 48578046
HOXB4
Promoter (<=1kb)


chr17: 48578069
HOXB4
Promoter (<=1kb)


chr17: 48578075
HOXB4
Promoter (<=1kb)


chr17: 48578078
HOXB4
Promoter (<=1kb)


chr17: 48578090
HOXB4
Promoter (<=1kb)


chr17: 48578096
HOXB4
Promoter (<=1kb)


chr17: 48578099
HOXB4
Promoter (<=1kb)


chr17: 48578123
HOXB4
Promoter (<=1kb)


chr17: 48578125
HOXB4
Promoter (<=1kb)


chr17: 48578130
HOXB4
Promoter (<=1kb)


chr17: 48578137
HOXB4
Promoter (<=1kb)


chr17: 48578144
HOXB4
Promoter (<=1kb)


chr17: 48578147
HOXB4
Promoter (<=1kb)


chr17: 48578149
HOXB4
Promoter (<=1kb)


chr17: 48578150
HOXB4
Promoter (<=1kb)


chr17: 48578151
HOXB4
Promoter (<=1kb)


chr17: 48578154
HOXB4
Promoter (<=1kb)


chr17: 48578158
HOXB4
Promoter (<=1kb)


chr17: 48578165
HOXB4
Promoter (<=1kb)


chr17: 48578462
HOXB4
Promoter (<=1kb)


chr17: 48578468
HOXB4
Promoter (<=1kb)


chr17: 48578638
HOXB4
Promoter (<=1kb)


chr17: 48578650
HOXB4
Promoter (<=1kb)


chr17: 48578652
HOXB4
Promoter (<=1kb)


chr17: 48578654
HOXB4
Promoter (<=1kb)


chr17: 48578663
HOXB4
Promoter (<=1kb)


chr17: 48578685
HOXB4
Promoter (<=1kb)


chr17: 48578697
HOXB4
Promoter (<=1kb)


chr17: 48581942
MIR10A
Promoter (<=1kb)


chr17: 48581956
MIR10A
Promoter (<=1kb)


chr17: 48581999
MIR10A
Promoter (<=1kb)


chr17: 48582001
MIR10A
Promoter (<=1kb)


chr17: 48582003
MIR10A
Promoter (<=1kb)


chr17: 48582024
MIR10A
Promoter (<=1kb)


chr17: 48582192
MIR10A
Promoter (<=1kb)


chr17: 48582200
MIR10A
Promoter (<=1kb)


chr17: 48582204
MIR10A
Promoter (<=1kb)


chr17: 48582210
MIR10A
Promoter (<=1kb)


chr17: 48582236
MIR10A
Promoter (<=1kb)


chr17: 48582239
MIR10A
Promoter (<=1kb)


chr17: 48582242
MIR10A
Promoter (<=1kb)


chr17: 48582245
MIR10A
Promoter (<=1kb)


chr17: 48582247
MIR10A
Promoter (<=1kb)


chr17: 48582273
MIR10A
Promoter (<=1kb)


chr17: 48582275
MIR10A
Promoter (<=1kb)


chr17: 48582279
MIR10A
Promoter (<=1kb)


chr17: 48582394
MIR10A
Promoter (<=1kb)


chr17: 48582395
MIR10A
Promoter (<=1kb)


chr17: 48582396
MIR10A
Promoter (<=1kb)


chr17: 48582397
MIR10A
Promoter (<=1kb)


chr17: 48582399
MIR10A
Promoter (<=1kb)


chr17: 48582400
MIR10A
Promoter (<=1kb)


chr17: 48582402
MIR10A
Promoter (<=1kb)


chr17: 48582403
MIR10A
Promoter (<=1kb)


chr17: 48582414
MIR10A
Promoter (<=1kb)


chr17: 48582415
MIR10A
Promoter (<=1kb)


chr17: 48592664
HOXB-AS3
Promoter (<=1kb)


chr17: 48592684
HOXB-AS3
Promoter (<=1kb)


chr17: 48592685
HOXB-AS3
Promoter (<=1kb)


chr17: 48592719
HOXB-AS3
Promoter (<=1kb)


chr17: 48592723
HOXB-AS3
Promoter (<=1kb)


chr17: 48592727
HOXB-AS3
Promoter (<=1kb)


chr17: 48633961
HOXB7
Promoter (<=1kb)


chr17: 48633996
HOXB7
Promoter (<=1kb)


chr17: 48633999
HOXB7
Promoter (<=1kb)


chr17: 48634007
HOXB7
Promoter (<=1kb)


chr17: 48634029
HOXB7
Promoter (<=1kb)


chr17: 48719037
PRAC1
Downstream (2-3kb)


chr17: 48719038
PRAC1
Downstream (2-3kb)


chr17: 48719043
PRAC1
Downstream (2-3kb)


chr17: 48719050
PRAC1
Downstream (2-3kb)


chr17: 48719294
PRAC1
Downstream (2-3kb)


chr17: 48719300
PRAC1
Downstream (2-3kb)


chr17: 48719354
PRAC1
Downstream (2-3kb)


chr17: 48754998
HOXB13
Distal Intergenic


chr17: 48755007
HOXB13
Distal Intergenic


chr17: 48755023
HOXB13
Distal Intergenic


chr17: 48755032
HOXB13
Distal Intergenic


chr17: 48755052
HOXB13
Distal Intergenic


chr17: 48755064
HOXB13
Distal Intergenic


chr17: 48755066
HOXB13
Distal Intergenic


chr17: 49910367
DLX4
Distal Intergenic


chr17: 49910377
DLX4
Distal Intergenic


chr17: 49910422
DLX4
Distal Intergenic


chr17: 49910427
DLX4
Distal Intergenic


chr17: 49910431
DLX4
Distal Intergenic


chr17: 59838380
VMP1
Promoter (<=1kb)


chr17: 63497324
ACE
Promoter (1-2kb)


chr17: 63497336
ACE
Promoter (1-2kb)


chr17: 63497337
ACE
Promoter (1-2kb)


chr17: 63497342
ACE
Promoter (1-2kb)


chr17: 63497343
ACE
Promoter (1-2kb)


chr17: 63527046
KCNH6
Intron (ENST00000583465.1/81033, intron 2 of 12)


chr17: 72117887
SOX9-AS1
Promoter (<=1kb)


chr17: 72117889
SOX9-AS1
Promoter (<=1kb)


chr17: 72117911
SOX9-AS1
Promoter (<=1kb)


chr17: 72117945
SOX9-AS1
Promoter (<=1kb)


chr17: 72117980
SOX9-AS1
Promoter (<=1kb)


chr17: 72117988
SOX9-AS1
Promoter (<=1kb)


chr17: 72117989
SOX9-AS1
Promoter (<=1kb)


chr17: 72118013
SOX9-AS1
Promoter (<=1kb)


chr17: 72661504
LINC00511
Intron (ENST00000255559.7/201266, intron 7 of 9)


chr17: 72661511
LINC00511
Intron (ENST00000255559.7/201266, intron 7 of 9)


chr17: 74852750
GRIN2C
Exon (ENST00000584176.1/2905, exon 2 of 9)


chr17: 74852761
GRIN2C
Exon (ENST00000584176.1/2905, exon 2 of 9)


chr17: 74852762
GRIN2C
Exon (ENST00000584176.1/2905, exon 2 of 9)


chr17: 74852779
GRIN2C
Exon (ENST00000584176.1/2905, exon 2 of 9)


chr17: 74852780
GRIN2C
Exon (ENST00000584176.1/2905, exon 2 of 9)


chr17: 78231866
TMEM235
Promoter (<=1kb)


chr17: 78231868
TMEM235
Promoter (<=1kb)


chr17: 78231879
TMEM235
Promoter (<=1kb)


chr17: 78231881
TMEM235
Promoter (<=1kb)


chr17: 78231891
TMEM235
Promoter (<=1kb)


chr17: 78231897
TMEM235
Promoter (<=1kb)


chr17: 78232001
TMEM235
Promoter (<=1kb)


chr17: 78232011
TMEM235
Promoter (<=1kb)


chr17: 78232038
TMEM235
Promoter (<=1kb)


chr17: 78232040
TMEM235
Promoter (<=1kb)


chr17: 78232056
TMEM235
Promoter (<=1kb)


chr17: 78232108
TMEM235
Promoter (<=1kb)


chr17: 78232138
TMEM235
Promoter (<=1kb)


chr17: 78232165
TMEM235
Promoter (<=1kb)


chr17: 78232167
TMEM235
Promoter (<=1kb)


chr17: 78232184
TMEM235
Promoter (<=1kb)


chr17: 78232185
TMEM235
Promoter (<=1kb)


chr17: 78232190
TMEM235
Promoter (<=1kb)


chr17: 78232191
TMEM235
Promoter (<=1kb)


chr17: 78232201
TMEM235
Promoter (<=1kb)


chr17: 78232209
TMEM235
Promoter (<=1kb)


chr17: 78232210
TMEM235
Promoter (<=1kb)


chr17: 78505214
DNAH17
Intron (ENST00000389840.6/8632, intron 31 of 80)


chr17: 78505227
DNAH17
Intron (ENST00000389840.6/8632, intron 31 of 80)


chr17: 78505240
DNAH17
Intron (ENST00000389840.6/8632, intron 31 of 80)


chr17: 78505242
DNAH17
Intron (ENST00000389840.6/8632, intron 31 of 80)


chr17: 81223460
CEP131
Promoter (<=1kb)


chr17: 81223477
CEP131
Promoter (<=1kb)


chr17: 81223481
CEP131
Promoter (<=1kb)


chr17: 81223483
CEP131
Promoter (<=1kb)


chr17: 81223599
CEP131
Promoter (<=1kb)


chr17: 81223604
CEP131
Promoter (<=1kb)


chr17: 81223609
CEP131
Promoter (<=1kb)


chr17: 81223613
CEP131
Promoter (<=1kb)


chr17: 81223619
CEP131
Promoter (<=1kb)


chr17: 81223659
CEP131
Promoter (<=1kb)


chr17: 81688133
HGS
Promoter (1-2kb)


chr17: 81688134
HGS
Promoter (1-2kb)


chr17: 81688137
HGS
Promoter (1-2kb)


chr17: 81688138
HGS
Promoter (1-2kb)


chr17: 81688140
HGS
Promoter (1-2kb)


chr17: 81688141
HGS
Promoter (1-2kb)


chr17: 81688149
HGS
Promoter (1-2kb)


chr17: 81688150
HGS
Promoter (1-2kb)


chr17: 81688162
HGS
Promoter (1-2kb)


chr17: 81688163
HGS
Promoter (1-2kb)


chr17: 81688165
HGS
Promoter (1-2kb)


chr17: 81688166
HGS
Promoter (1-2kb)


chr17: 81688171
HGS
Promoter (1-2kb)


chr17: 81688172
HGS
Promoter (1-2kb)


chr17: 81688180
HGS
Promoter (1-2kb)


chr17: 81688181
HGS
Promoter (1-2kb)


chr17: 81688186
HGS
Promoter (1-2kb)


chr17: 81688187
HGS
Promoter (1-2kb)


chr17: 81688188
HGS
Promoter (1-2kb)


chr17: 81688189
HGS
Promoter (1-2kb)


chr17: 81688245
HGS
Promoter (1-2kb)


chr17: 81688273
HGS
Promoter (2-3kb)


chr17: 81688284
HGS
Promoter (2-3kb)


chr17: 81688286
HGS
Promoter (2-3kb)


chr17: 81688315
HGS
Promoter (2-3kb)


chr17: 81688329
HGS
Promoter (2-3kb)


chr17: 81688363
HGS
Promoter (2-3kb)


chr17: 81688372
HGS
Promoter (2-3kb)


chr17: 82236900
MIR6787
Promoter (<=1kb)


chr17: 82236921
SLC16A3
Promoter (<=1kb)


chr17: 82236977
SLC16A3
Promoter (<=1kb)


chr18: 9404635
TWSG1
Distal Intergenic


chr18: 9404670
TWSG1
Distal Intergenic


chr18: 9404703
TWSG1
Distal Intergenic


chr18: 9404721
TWSG1
Distal Intergenic


chr18: 47246674
SKOR2
Promoter (2-3kb)


chr18: 47246680
SKOR2
Promoter (2-3kb)


chr18: 47246692
SKOR2
Promoter (2-3kb)


chr18: 47246705
SKOR2
Promoter (2-3kb)


chr18: 57428706
ONECUT2
Exon (ENST00000620778.1/ENST00000620778.1, exon 1 of 1)


chr18: 57428712
ONECUT2
Exon (ENST00000620778.1/ENST00000620778.1, exon 1 of 1)


chr18: 57428714
ONECUT2
Exon (ENST00000620778.1/ENST00000620778.1, exon 1 of 1)


chr18: 57428717
ONECUT2
Exon (ENST00000620778.1/ENST00000620778.1, exon 1 of 1)


chr18: 57428722
ONECUT2
Exon (ENST00000620778.1/ENST00000620778.1, exon 1 of 1)


chr18: 57428728
ONECUT2
Exon (ENST00000620778.1/ENST00000620778.1, exon 1 of 1)


chr18: 57428735
ONECUT2
Exon (ENST00000620778.1/ENST00000620778.1, exon 1 of 1)


chr18: 57428748
ONECUT2
Exon (ENST00000620778.1/ENST00000620778.1, exon 1 of 1)


chr18: 57428862
ONECUT2
Exon (ENST00000620778.1/ENST00000620778.1, exon 1 of 1)


chr18: 57428872
ONECUT2
Exon (ENST00000620778.1/ENST00000620778.1, exon 1 of 1)


chr18: 57428877
ONECUT2
Exon (ENST00000620778.1/ENST00000620778.1, exon 1 of 1)


chr18: 57428883
ONECUT2
Exon (ENST00000620778.1/ENST00000620778.1, exon 1 of 1)


chr18: 57428886
ONECUT2
Exon (ENST00000620778.1/ENST00000620778.1, exon 1 of 1)


chr18: 57428890
ONECUT2
Exon (ENST00000620778.1/ENST00000620778.1, exon 1 of 1)


chr18: 57428892
ONECUT2
Exon (ENST00000620778.1/ENST00000620778.1, exon 1 of 1)


chr18: 57440615
ONECUT2
Intron (ENST00000491143.3/9480, intron 1 of 1)


chr18: 57440635
ONECUT2
Intron (ENST00000491143.3/9480, intron 1 of 1)


chr18: 57440640
ONECUT2
Intron (ENST00000491143.3/9480, intron 1 of 1)


chr18: 57440643
ONECUT2
Intron (ENST00000491143.3/9480, intron 1 of 1)


chr18: 57440650
ONECUT2
Intron (ENST00000491143.3/9480, intron 1 of 1)


chr18: 57440663
ONECUT2
Intron (ENST00000491143.3/9480, intron 1 of 1)


chr18: 57440687
ONECUT2
Intron (ENST00000491143.3/9480, intron 1 of 1)


chr18: 57440688
ONECUT2
Intron (ENST00000491143.3/9480, intron 1 of 1)


chr18: 57440689
ONECUT2
Intron (ENST00000491143.3/9480, intron 1 of 1)


chr18: 57440690
ONECUT2
Intron (ENST00000491143.3/9480, intron 1 of 1)


chr18: 57440693
ONECUT2
Intron (ENST00000491143.3/9480, intron 1 of 1)


chr18: 57440694
ONECUT2
Intron (ENST00000491143.3/9480, intron 1 of 1)


chr18: 57440707
ONECUT2
Intron (ENST00000491143.3/9480, intron 1 of 1)


chr18: 57440712
ONECUT2
Intron (ENST00000491143.3/9480, intron 1 of 1)


chr18: 59274104
RAX
Promoter (<=1kb)


chr18: 59274109
RAX
Promoter (<=1kb)


chr18: 59274158
RAX
Promoter (<=1kb)


chr18: 59274159
RAX
Promoter (<=1kb)


chr18: 59274162
RAX
Promoter (<=1kb)


chr18: 59274163
RAX
Promoter (<=1kb)


chr18: 68693301
TMX3
Promoter (1-2kb)


chr18: 68693328
TMX3
Promoter (1-2kb)


chr18: 68693329
TMX3
Promoter (1-2kb)


chr18: 68693347
TMX3
Promoter (1-2kb)


chr19: 290792
PLPP2
Promoter (<=1kb)


chr19: 290802
PLPP2
Promoter (<=1kb)


chr19: 290808
PLPP2
Promoter (<=1kb)


chr19: 290815
PLPP2
Promoter (<=1kb)


chr19: 290821
PLPP2
Promoter (<=1kb)


chr19: 290838
PLPP2
Promoter (<=1kb)


chr19: 290855
PLPP2
Promoter (<=1kb)


chr19: 290857
PLPP2
Promoter (<=1kb)


chr19: 290859
PLPP2
Promoter (<=1kb)


chr19: 290860
PLPP2
Promoter (<=1kb)


chr19: 290864
PLPP2
Promoter (<=1kb)


chr19: 290865
PLPP2
Promoter (<=1kb)


chr19: 290870
PLPP2
Promoter (<=1kb)


chr19: 290871
PLPP2
Promoter (<=1kb)


chr19: 290886
PLPP2
Promoter (<=1kb)


chr19: 290892
PLPP2
Promoter (<=1kb)


chr19: 290894
PLPP2
Promoter (<=1kb)


chr19: 795362
PTBP1
Promoter (1-2kb)


chr19: 795377
PTBP1
Promoter (1-2kb)


chr19: 795395
PTBP1
Promoter (1-2kb)


chr19: 795396
PTBP1
Promoter (1-2kb)


chr19: 795399
PTBP1
Promoter (1-2kb)


chr19: 795400
PTBP1
Promoter (1-2kb)


chr19: 795417
PTBP1
Promoter (1-2kb)


chr19: 795418
PTBP1
Promoter (1-2kb)


chr19: 795421
PTBP1
Promoter (1-2kb)


chr19: 1007560
TMEM259
Intron (ENST00000234389.3/116444, intron 3 of 8)


chr19: 1007563
TMEM259
Intron (ENST00000234389.3/116444, intron 3 of 8)


chr19: 1007565
TMEM259
Intron (ENST00000234389.3/116444, intron 3 of 8)


chr19: 1007606
TMEM259
Intron (ENST00000234389.3/116444, intron 3 of 8)


chr19: 1007612
TMEM259
Intron (ENST00000234389.3/116444, intron 3 of 8)


chr19: 1007622
TMEM259
Intron (ENST00000234389.3/116444, intron 3 of 8)


chr19: 1007624
TMEM259
Intron (ENST00000234389.3/116444, intron 3 of 8)


chr19: 1429508
DAZAP1
Intron (ENST00000336761.10/26528, intron 8 of 12)


chr19: 1429513
DAZAP1
Intron (ENST00000336761.10/26528, intron 8 of 12)


chr19: 1429541
DAZAP1
Intron (ENST00000336761.10/26528, intron 8 of 12)


chr19: 1429544
DAZAP1
Intron (ENST00000336761.10/26528, intron 8 of 12)


chr19: 1429554
DAZAP1
Intron (ENST00000336761.10/26528, intron 8 of 12)


chr19: 2251245
MIR4321
Promoter (<=1kb)


chr19: 2251266
MIR4321
Promoter (<=1kb)


chr19: 2251275
MIR4321
Promoter (<=1kb)


chr19: 2251278
MIR4321
Promoter (<=1kb)


chr19: 2251301
MIR4321
Promoter (<=1kb)


chr19: 2251309
MIR4321
Promoter (<=1kb)


chr19: 2251366
MIR4321
Promoter (<=1kb)


chr19: 2251374
MIR4321
Promoter (<=1kb)


chr19: 2251377
MIR4321
Promoter (<=1kb)


chr19: 2251380
MIR4321
Promoter (<=1kb)


chr19: 2251383
MIR4321
Promoter (<=1kb)


chr19: 2251392
MIR4321
Promoter (<=1kb)


chr19: 2251407
MIR4321
Promoter (<=1kb)


chr19: 2251409
MIR4321
Promoter (<=1kb)


chr19: 2251429
MIR4321
Promoter (<=1kb)


chr19: 2251432
MIR4321
Promoter (<=1kb)


chr19: 2251439
MIR4321
Promoter (<=1kb)


chr19: 2251446
MIR4321
Promoter (<=1kb)


chr19: 2251480
MIR4321
Promoter (<=1kb)


chr19: 2251489
MIR4321
Promoter (<=1kb)


chr19: 2251491
MIR4321
Promoter (<=1kb)


chr19: 2251499
MIR4321
Promoter (<=1kb)


chr19: 2251501
MIR4321
Promoter (<=1kb)


chr19: 2252251
MIR4321
Promoter (1-2kb)


chr19: 2252255
MIR4321
Promoter (1-2kb)


chr19: 2252264
MIR4321
Promoter (1-2kb)


chr19: 2252275
MIR4321
Promoter (1-2kb)


chr19: 2252284
MIR4321
Promoter (1-2kb)


chr19: 2252286
MIR4321
Promoter (1-2kb)


chr19: 2252291
MIR4321
Promoter (1-2kb)


chr19: 2252540
MIR4321
Promoter (1-2kb)


chr19: 2252542
MIR4321
Promoter (1-2kb)


chr19: 2252589
MIR4321
Promoter (1-2kb)


chr19: 2252591
MIR4321
Promoter (1-2kb)


chr19: 2252607
MIR4321
Promoter (1-2kb)


chr19: 4449490
UBXN6
Promoter (<=1kb)


chr19: 4450001
UBXN6
Promoter (1-2kb)


chr19: 4450012
UBXN6
Promoter (1-2kb)


chr19: 4450026
UBXN6
Promoter (1-2kb)


chr19: 17497308
SLC27A1
Promoter (1-2kb)


chr19: 17497313
SLC27A1
Promoter (1-2kb)


chr19: 17497321
SLC27A1
Promoter (1-2kb)


chr19: 17497327
SLC27A1
Promoter (1-2kb)


chr19: 17497329
SLC27A1
Promoter (1-2kb)


chr19: 17497333
SLC27A1
Promoter (1-2kb)


chr19: 33811373
KCTD15
Exon (ENST00000590385.2/79047, exon 2 of 2)


chr19: 33811375
KCTD15
Exon (ENST00000590385.2/79047, exon 2 of 2)


chr19: 34668203
SCGB2B2
Intron (ENST00000601241.5/284402, intron 1 of 3)


chr19: 34668207
SCGB2B2
Intron (ENST00000601241.5/284402, intron 1 of 3)


chr19: 34668224
SCGB2B2
Intron (ENST00000601241.5/284402, intron 1 of 3)


chr19: 34668229
SCGB2B2
Intron (ENST00000601241.5/284402, intron 1 of 3)


chr19: 34668235
SCGB2B2
Intron (ENST00000601241.5/284402, intron 1 of 3)


chr19: 34668260
SCGB2B2
Intron (ENST00000601241.5/284402, intron 1 of 3)


chr19: 34668278
SCGB2B2
Intron (ENST00000601241.5/284402, intron 1 of 3)


chr19: 34668285
SCGB2B2
Intron (ENST00000601241.5/284402, intron 1 of 3)


chr19: 34668387
SCGB2B2
Intron (ENST00000601241.5/284402, intron 1 of 3)


chr19: 34668399
SCGB2B2
Intron (ENST00000601241.5/284402, intron 1 of 3)


chr19: 34668537
SCGB2B2
Intron (ENST00000601241.5/284402, intron 1 of 3)


chr19: 34668540
SCGB2B2
Intron (ENST00000601241.5/284402, intron 1 of 3)


chr19: 34668542
SCGB2B2
Intron (ENST00000601241.5/284402, intron 1 of 3)


chr19: 37007801
ZNF420
Promoter (<=1kb)


chr19: 37007807
ZNF420
Promoter (<=1kb)


chr19: 37007809
ZNF420
Promoter (<=1kb)


chr19: 38291920
SPINT2
Promoter (1-2kb)


chr19: 38291921
SPINT2
Promoter (1-2kb)


chr19: 38291935
SPINT2
Promoter (1-2kb)


chr19: 38291936
SPINT2
Promoter (1-2kb)


chr19: 38291945
SPINT2
Promoter (1-2kb)


chr19: 38291950
SPINT2
Promoter (1-2kb)


chr19: 38395561
SPRED3
Exon (ENST00000338502.8/399473, exon 5 of 5)


chr19: 38395565
SPRED3
Exon (ENST00000338502.8/399473, exon 5 of 5)


chr19: 38395567
SPRED3
Exon (ENST00000338502.8/399473, exon 5 of 5)


chr19: 38395573
SPRED3
Exon (ENST00000338502.8/399473, exon 5 of 5)


chr19: 38395608
SPRED3
Exon (ENST00000338502.8/399473, exon 5 of 5)


chr19: 38395609
SPRED3
Exon (ENST00000338502.8/399473, exon 5 of 5)


chr19: 38395623
SPRED3
Exon (ENST00000338502.8/399473, exon 5 of 5)


chr19: 38395624
SPRED3
Exon (ENST00000338502.8/399473, exon 5 of 5)


chr19: 38395626
SPRED3
Exon (ENST00000338502.8/399473, exon 5 of 5)


chr19: 38395627
SPRED3
Exon (ENST00000338502.8/399473, exon 5 of 5)


chr19: 38395891
SPRED3
Exon (ENST00000338502.8/399473, exon 5 of 5)


chr19: 38395894
SPRED3
Exon (ENST00000338502.8/399473, exon 5 of 5)


chr19: 38395914
SPRED3
Exon (ENST00000338502.8/399473, exon 5 of 5)


chr19: 38395917
SPRED3
Exon (ENST00000338502.8/399473, exon 5 of 5)


chr19: 38395944
SPRED3
Exon (ENST00000338502.8/399473, exon 5 of 5)


chr19: 38395948
SPRED3
Exon (ENST00000338502.8/399473, exon 5 of 5)


chr19: 38395951
SPRED3
Exon (ENST00000338502.8/399473, exon 5 of 5)


chr19: 38395965
SPRED3
Exon (ENST00000338502.8/399473, exon 5 of 5)


chr19: 38395971
SPRED3
Exon (ENST00000338502.8/399473, exon 5 of 5)


chr19: 38395975
SPRED3
Exon (ENST00000338502.8/399473, exon 5 of 5)


chr19: 38395981
SPRED3
Exon (ENST00000338502.8/399473, exon 5 of 5)


chr19: 38395994
SPRED3
Exon (ENST00000338502.8/399473, exon 5 of 5)


chr19: 38395996
SPRED3
Exon (ENST00000338502.8/399473, exon 5 of 5)


chr19: 38396001
SPRED3
Exon (ENST00000338502.8/399473, exon 5 of 5)


chr19: 38396004
SPRED3
Exon (ENST00000338502.8/399473, exon 5 of 5)


chr19: 38396006
SPRED3
Exon (ENST00000338502.8/399473, exon 5 of 5)


chr19: 38396008
SPRED3
Exon (ENST00000338502.8/399473, exon 5 of 5)


chr19: 38396016
SPRED3
Exon (ENST00000338502.8/399473, exon 5 of 5)


chr19: 40567965
SPTBN4
3′ UTR


chr19: 40567967
SPTBN4
3′ UTR


chr19: 40567970
SPTBN4
3′ UTR


chr19: 40567971
SPTBN4
3′ UTR


chr19: 40567980
SPTBN4
3′ UTR


chr19: 40567981
SPTBN4
3′ UTR


chr19: 40567982
SPTBN4
3′ UTR


chr19: 40567983
SPTBN4
3′ UTR


chr19: 40567989
SPTBN4
3′ UTR


chr19: 40567990
SPTBN4
3′ UTR


chr19: 40567991
SPTBN4
3′ UTR


chr19: 40567992
SPTBN4
3′ UTR


chr19: 40567994
SPTBN4
3′ UTR


chr19: 40567995
SPTBN4
3′ UTR


chr19: 40567997
SPTBN4
3′ UTR


chr19: 40567998
SPTBN4
3′ UTR


chr19: 40568009
SPTBN4
3′ UTR


chr19: 40597053
LTBP4
Promoter (<=1kb)


chr19: 40597054
LTBP4
Promoter (<=1kb)


chr19: 40597055
LTBP4
Promoter (<=1kb)


chr19: 40597056
LTBP4
Promoter (<=1kb)


chr19: 40597057
LTBP4
Promoter (<=1kb)


chr19: 40597058
LTBP4
Promoter (<=1kb)


chr19: 40597060
LTBP4
Promoter (<=1kb)


chr19: 40597061
LTBP4
Promoter (<=1kb)


chr19: 40597064
LTBP4
Promoter (<=1kb)


chr19: 40597065
LTBP4
Promoter (<=1kb)


chr19: 40597070
LTBP4
Promoter (<=1kb)


chr19: 40597071
LTBP4
Promoter (<=1kb)


chr19: 40597074
LTBP4
Promoter (<=1kb)


chr19: 40597134
LTBP4
Promoter (<=1kb)


chr19: 40597140
LTBP4
Promoter (<=1kb)


chr19: 40597144
LTBP4
Promoter (<=1kb)


chr19: 40597150
LTBP4
Promoter (<=1kb)


chr19: 40597156
LTBP4
Promoter (<=1kb)


chr19: 40597168
LTBP4
Promoter (<=1kb)


chr19: 40597190
LTBP4
Promoter (<=1kb)


chr19: 40597202
LTBP4
Promoter (<=1kb)


chr19: 40597206
LTBP4
Promoter (<=1kb)


chr19: 40597214
LTBP4
Promoter (<=1kb)


chr19: 40597221
LTBP4
Promoter (<=1kb)


chr19: 40597224
LTBP4
Promoter (<=1kb)


chr19: 40597228
LTBP4
Promoter (<=1kb)


chr19: 40597233
LTBP4
Promoter (<=1kb)


chr19: 40597239
LTBP4
Promoter (<=1kb)


chr19: 40597255
LTBP4
Promoter (<=1kb)


chr19: 40609554
LTBP4
Promoter (<=1kb)


chr19: 40609570
LTBP4
Promoter (<=1kb)


chr19: 40609571
LTBP4
Promoter (<=1kb)


chr19: 40609580
LTBP4
Promoter (<=1kb)


chr19: 40609581
LTBP4
Promoter (<=1kb)


chr19: 40609600
LTBP4
Promoter (<=1kb)


chr19: 40609601
LTBP4
Promoter (<=1kb)


chr19: 40609612
LTBP4
Promoter (<=1kb)


chr19: 40609613
LTBP4
Promoter (<=1kb)


chr19: 40609618
LTBP4
Promoter (<=1kb)


chr19: 40609619
LTBP4
Promoter (<=1kb)


chr19: 40609754
LTBP4
Promoter (<=1kb)


chr19: 40609764
LTBP4
Promoter (<=1kb)


chr19: 40609766
LTBP4
Promoter (<=1kb)


chr19: 40609774
LTBP4
Promoter (<=1kb)


chr19: 40609790
LTBP4
Promoter (<=1kb)


chr19: 40609791
LTBP4
Promoter (<=1kb)


chr19: 40609795
LTBP4
Promoter (<=1kb)


chr19: 40609796
LTBP4
Promoter (<=1kb)


chr19: 40609817
LTBP4
Promoter (<=1kb)


chr19: 40609818
LTBP4
Promoter (<=1kb)


chr19: 40609822
LTBP4
Promoter (<=1kb)


chr19: 40609823
LTBP4
Promoter (<=1kb)


chr19: 40609828
LTBP4
Promoter (<=1kb)


chr19: 40609829
LTBP4
Promoter (<=1kb)


chr19: 40614332
LTBP4
Promoter (<=1kb)


chr19: 40614336
LTBP4
Promoter (<=1kb)


chr19: 40614353
LTBP4
Promoter (<=1kb)


chr19: 40614358
LTBP4
Promoter (<=1kb)


chr19: 40614363
LTBP4
Promoter (<=1kb)


chr19: 40623976
LTBP4
Promoter (<=1kb)


chr19: 40623980
LTBP4
Promoter (<=1kb)


chr19: 41904348
ARHGEF1
Promoter (<=1kb)


chr19: 41904359
ARHGEF1
Promoter (<=1kb)


chr19: 41904369
ARHGEF1
Promoter (<=1kb)


chr19: 41904371
ARHGEF1
Promoter (<=1kb)


chr19: 50506480
JOSD2
Promoter (1-2kb)


chr19: 50506485
JOSD2
Promoter (1-2kb)


chr19: 50506506
JOSD2
Promoter (1-2kb)


chr19: 50506511
JOSD2
Promoter (1-2kb)


chr19: 50506515
JOSD2
Promoter (1-2kb)


chr19: 53982494
MIR935
Promoter (<=1kb)


chr19: 53982504
MIR935
Promoter (<=1kb)


chr19: 53982505
MIR935
Promoter (<=1kb)


chr19: 53982523
MIR935
Promoter (<=1kb)


chr19: 53982606
MIR935
Promoter (<=1kb)


chr19: 53982609
MIR935
Promoter (<=1kb)


chr19: 53982612
MIR935
Promoter (<=1kb)


chr19: 53982621
MIR935
Promoter (<=1kb)


chr19: 53982681
MIR935
Promoter (<=1kb)


chr19: 53982682
MIR935
Promoter (<=1kb)


chr19: 53982698
MIR935
Promoter (<=1kb)


chr19: 53982699
MIR935
Promoter (<=1kb)


chr19: 53982702
MIR935
Promoter (<=1kb)


chr19: 53982705
MIR935
Promoter (<=1kb)


chr19: 53982708
MIR935
Promoter (<=1kb)


chr19: 53982709
MIR935
Promoter (<=1kb)


chr19: 53982714
MIR935
Promoter (<=1kb)


chr19: 53982720
MIR935
Promoter (<=1kb)


chr19: 53982735
MIR935
Promoter (<=1kb)


chr19: 53982736
MIR935
Promoter (<=1kb)


chr19: 53982740
MIR935
Promoter (<=1kb)


chr19: 53982741
MIR935
Promoter (<=1kb)


chr19: 53982744
MIR935
Promoter (<=1kb)


chr19: 53982747
MIR935
Promoter (<=1kb)


chr19: 53982751
MIR935
Promoter (<=1kb)


chr19: 53982752
MIR935
Promoter (<=1kb)


chr19: 53982753
MIR935
Promoter (<=1kb)


chr19: 53982760
MIR935
Promoter (<=1kb)


chr19: 53982770
MIR935
Promoter (<=1kb)


chr19: 53982875
MIR935
Promoter (<=1kb)


chr19: 57935179
ZNF418
Promoter (<=1kb)


chr19: 57935180
ZNF418
Promoter (<=1kb)


chr19: 57935181
ZNF418
Promoter (<=1kb)


chr19: 57935186
ZNF418
Promoter (<=1kb)


chr19: 57935188
ZNF418
Promoter (<=1kb)


chr19: 57935189
ZNF418
Promoter (<=1kb)


chr19: 57935202
ZNF418
Promoter (<=1kb)


chr19: 57935203
ZNF418
Promoter (<=1kb)


chr19: 57935204
ZNF418
Promoter (<=1kb)


chr19: 57935205
ZNF418
Promoter (<=1kb)


chr2: 10043082
KLF11
Promoter (<=1kb)


chr2: 10043088
KLF11
Promoter (<=1kb)


chr2: 42101596
PKDCC
Distal Intergenic


chr2: 42101598
PKDCC
Distal Intergenic


chr2: 42101601
PKDCC
Distal Intergenic


chr2: 42101625
PKDCC
Distal Intergenic


chr2: 42101627
PKDCC
Distal Intergenic


chr2: 42101633
PKDCC
Distal Intergenic


chr2: 43224454
ZFP36L2
Promoter (2-3kb)


chr2: 43224469
ZFP36L2
Promoter (2-3kb)


chr2: 43224471
ZFP36L2
Promoter (2-3kb)


chr2: 43224474
ZFP36L2
Promoter (2-3kb)


chr2: 43224480
ZFP36L2
Promoter (2-3kb)


chr2: 43224484
ZFP36L2
Promoter (2-3kb)


chr2: 43224489
ZFP36L2
Promoter (2-3kb)


chr2: 43224497
ZFP36L2
Promoter (2-3kb)


chr2: 43224500
ZFP36L2
Promoter (2-3kb)


chr2: 43224502
ZFP36L2
Promoter (2-3kb)


chr2: 43225009
ZFP36L2
Promoter (1-2kb)


chr2: 43225012
ZFP36L2
Promoter (1-2kb)


chr2: 43225021
ZFP36L2
Promoter (1-2kb)


chr2: 43225082
ZFP36L2
Promoter (1-2kb)


chr2: 43225087
ZFP36L2
Promoter (1-2kb)


chr2: 43225089
ZFP36L2
Promoter (1-2kb)


chr2: 43225091
ZFP36L2
Promoter (1-2kb)


chr2: 44929769
LINC01833
Intron (ENST00000437916.2/107985879, intron 1 of 1)


chr2: 44929799
LINC01833
Intron (ENST00000437916.2/107985879, intron 1 of 1)


chr2: 44929802
LINC01833
Intron (ENST00000437916.2/107985879, intron 1 of 1)


chr2: 64609327
LINC02579
Promoter (1-2kb)


chr2: 64609338
LINC02579
Promoter (2-3kb)


chr2: 64609342
LINC02579
Promoter (2-3kb)


chr2: 64609368
LINC02579
Promoter (2-3kb)


chr2: 64609373
LINC02579
Promoter (2-3kb)


chr2: 64609383
LINC02579
Promoter (2-3kb)


chr2: 64609403
LINC02579
Promoter (2-3kb)


chr2: 64609404
LINC02579
Promoter (2-3kb)


chr2: 64609407
LINC02579
Promoter (2-3kb)


chr2: 64609408
LINC02579
Promoter (2-3kb)


chr2: 74499366
LBX2
Promoter (<=1kb)


chr2: 74499368
LBX2
Promoter (<=1kb)


chr2: 74499398
LBX2
Promoter (<=1kb)


chr2: 74499400
LBX2
Promoter (<=1kb)


chr2: 74499407
LBX2
Promoter (<=1kb)


chr2: 74499410
LBX2
Promoter (<=1kb)


chr2: 74499413
LBX2
Promoter (<=1kb)


chr2: 74499427
LBX2
Promoter (<=1kb)


chr2: 74499442
LBX2
Promoter (<=1kb)


chr2: 74499445
LBX2
Promoter (<=1kb)


chr2: 74499458
LBX2
Promoter (<=1kb)


chr2: 74499470
LBX2
Promoter (<=1kb)


chr2: 74499811
LBX2
Promoter (<=1kb)


chr2: 74499822
LBX2
Promoter (<=1kb)


chr2: 74499824
LBX2
Promoter (<=1kb)


chr2: 74499829
LBX2
Promoter (<=1kb)


chr2: 74499834
LBX2
Promoter (<=1kb)


chr2: 74499842
LBX2
Promoter (<=1kb)


chr2: 98539614
INPP4A
Exon (ENST00000409016.8/3631, exon 10 of 26)


chr2: 98539629
INPP4A
Exon (ENST00000409016.8/3631, exon 10 of 26)


chr2: 106065547
ECRG4
Promoter (<=1kb)


chr2: 106065562
ECRG4
Promoter (<=1kb)


chr2: 106065572
ECRG4
Promoter (<=1kb)


chr2: 106065576
ECRG4
Promoter (<=1kb)


chr2: 106065580
ECRG4
Promoter (<=1kb)


chr2: 106065587
ECRG4
Promoter (<=1kb)


chr2: 106065616
ECRG4
Promoter (<=1kb)


chr2: 106065618
ECRG4
Promoter (<=1kb)


chr2: 106065621
ECRG4
Promoter (<=1kb)


chr2: 106065629
ECRG4
Promoter (<=1kb)


chr2: 106065639
ECRG4
Promoter (<=1kb)


chr2: 106065652
ECRG4
Promoter (<=1kb)


chr2: 106065665
ECRG4
Promoter (<=1kb)


chr2: 106065666
ECRG4
Promoter (<=1kb)


chr2: 106065667
ECRG4
Promoter (<=1kb)


chr2: 106065668
ECRG4
Promoter (<=1kb)


chr2: 106065671
ECRG4
Promoter (<=1kb)


chr2: 106065672
ECRG4
Promoter (<=1kb)


chr2: 106065673
ECRG4
Promoter (<=1kb)


chr2: 106065674
ECRG4
Promoter (<=1kb)


chr2: 106065681
ECRG4
Promoter (<=1kb)


chr2: 106065682
ECRG4
Promoter (<=1kb)


chr2: 106065685
ECRG4
Promoter (<=1kb)


chr2: 106065686
ECRG4
Promoter (<=1kb)


chr2: 106065699
ECRG4
Promoter (<=1kb)


chr2: 106065701
ECRG4
Promoter (<=1kb)


chr2: 106065715
ECRG4
Promoter (<=1kb)


chr2: 106065725
ECRG4
Promoter (<=1kb)


chr2: 106065732
ECRG4
Promoter (<=1kb)


chr2: 106065739
ECRG4
Promoter (<=1kb)


chr2: 106065751
ECRG4
Promoter (<=1kb)


chr2: 106065782
ECRG4
Promoter (<=1kb)


chr2: 106065784
ECRG4
Promoter (<=1kb)


chr2: 106065814
ECRG4
Promoter (<=1kb)


chr2: 106065849
ECRG4
Promoter (<=1kb)


chr2: 106065925
ECRG4
Promoter (<=1kb)


chr2: 106065929
ECRG4
Promoter (<=1kb)


chr2: 106065943
ECRG4
Promoter (<=1kb)


chr2: 106065946
ECRG4
Promoter (<=1kb)


chr2: 120887649
GLI2
Intron (ENST00000341310.10/2736, intron 2 of 9)


chr2: 120887681
GLI2
Intron (ENST00000341310.10/2736, intron 2 of 9)


chr2: 176082272
EVX2
Promoter (1-2kb)


chr2: 176082274
EVX2
Promoter (1-2kb)


chr2: 176082276
EVX2
Promoter (1-2kb)


chr2: 176082285
EVX2
Promoter (1-2kb)


chr2: 176082287
EVX2
Promoter (1-2kb)


chr2: 176082288
EVX2
Promoter (1-2kb)


chr2: 176082295
EVX2
Promoter (1-2kb)


chr2: 176082296
EVX2
Promoter (1-2kb)


chr2: 176082298
EVX2
Promoter (1-2kb)


chr2: 176082299
EVX2
Promoter (1-2kb)


chr2: 176082346
EVX2
Promoter (1-2kb)


chr2: 176082349
EVX2
Promoter (1-2kb)


chr2: 176082351
EVX2
Promoter (1-2kb)


chr2: 176082357
EVX2
Promoter (1-2kb)


chr2: 176082360
EVX2
Promoter (1-2kb)


chr2: 176082369
EVX2
Promoter (1-2kb)


chr2: 176082391
EVX2
Promoter (1-2kb)


chr2: 176082404
EVX2
Promoter (1-2kb)


chr2: 176082410
EVX2
Promoter (1-2kb)


chr2: 176082413
EVX2
Promoter (1-2kb)


chr2: 176082416
EVX2
Promoter (1-2kb)


chr2: 176082430
EVX2
Promoter (1-2kb)


chr2: 176082435
EVX2
Promoter (1-2kb)


chr2: 176082444
EVX2
Promoter (1-2kb)


chr2: 176082462
EVX2
Promoter (1-2kb)


chr2: 176082463
EVX2
Promoter (1-2kb)


chr2: 176082472
EVX2
Promoter (1-2kb)


chr2: 176082473
EVX2
Promoter (1-2kb)


chr2: 176082503
EVX2
Promoter (1-2kb)


chr2: 176082514
EVX2
Promoter (1-2kb)


chr2: 176082516
EVX2
Promoter (1-2kb)


chr2: 176082518
EVX2
Promoter (1-2kb)


chr2: 176082523
EVX2
Promoter (1-2kb)


chr2: 176082534
EVX2
Promoter (1-2kb)


chr2: 205885781
NRP2
Distal Intergenic


chr2: 205885792
NRP2
Distal Intergenic


chr2: 205885798
NRP2
Distal Intergenic


chr2: 217978608
LOC105373878
Promoter (<=1kb)


chr2: 217978612
LOC105373878
Promoter (<=1kb)


chr2: 217978628
LOC105373878
Promoter (<=1kb)


chr2: 219496796
SPEGNB
Promoter (<=1kb)


chr2: 219496801
SPEGNB
Promoter (<=1kb)


chr2: 219496803
SPEGNB
Promoter (<=1kb)


chr2: 219496825
SPEGNB
Promoter (<=1kb)


chr2: 219496827
SPEGNB
Promoter (<=1kb)


chr2: 219496838
SPEGNB
Promoter (<=1kb)


chr2: 219496841
SPEGNB
Promoter (<=1kb)


chr2: 219496843
SPEGNB
Promoter (<=1kb)


chr2: 219496856
SPEGNB
Promoter (<=1kb)


chr2: 219496879
SPEGNB
Promoter (<=1kb)


chr2: 219496888
SPEGNB
Promoter (<=1kb)


chr2: 219496890
SPEGNB
Promoter (<=1kb)


chr2: 219522719
ASIC4
Intron (ENST00000461395.5/55515, intron 1 of 2)


chr2: 219522725
ASIC4
Intron (ENST00000461395.5/55515, intron 1 of 2)


chr2: 219522728
ASIC4
Intron (ENST00000461395.5/55515, intron 1 of 2)


chr2: 219522742
ASIC4
Intron (ENST00000461395.5/55515, intron 1 of 2)


chr2: 219522747
ASIC4
Intron (ENST00000461395.5/55515, intron 1 of 2)


chr2: 219522753
ASIC4
Intron (ENST00000461395.5/55515, intron 1 of 2)


chr2: 219522757
ASIC4
Intron (ENST00000461395.5/55515, intron 1 of 2)


chr2: 219522760
ASIC4
Intron (ENST00000461395.5/55515, intron 1 of 2)


chr2: 219522773
ASIC4
Intron (ENST00000461395.5/55515, intron 1 of 2)


chr2: 219522775
ASIC4
Intron (ENST00000461395.5/55515, intron 1 of 2)


chr20: 21391640
NKX2-4
Distal Intergenic


chr20: 21391647
NKX2-4
Distal Intergenic


chr20: 21391656
NKX2-4
Distal Intergenic


chr20: 21391658
NKX2-4
Distal Intergenic


chr20: 37915006
VSTM2L
Intron (ENST00000373459.4/128434, intron 1 of 1)


chr20: 37915009
VSTM2L
Intron (ENST00000373459.4/128434, intron 1 of 1)


chr20: 37915027
VSTM2L
Intron (ENST00000373459.4/128434, intron 1 of 1)


chr20: 37915028
VSTM2L
Intron (ENST00000373459.4/128434, intron 1 of 1)


chr20: 37915046
VSTM2L
Intron (ENST00000373459.4/128434, intron 1 of 1)


chr20: 37915053
VSTM2L
Intron (ENST00000373459.4/128434, intron 1 of 1)


chr20: 37915056
VSTM2L
Intron (ENST00000373459.4/128434, intron 1 of 1)









Example 5-Additional Methylation Markers for SCLC Subtype Classification, Diagnosis, and Treatment

Additional methylation sites associated with each SCLC subtype, SCLC-A. SCLC-N, SCLC-P, and SCLC-I were identified from analysis of methylation data from formalin-fixed paraffin-embedded (FFPE) tissue sections from SCLC patients. Methylation sites associated with SCLC-A are provided in Table 20. Methylation sites associated with SCLC-N are provided in Table 21. Methylation sites associated with SCLC-P are provided in Table 22. Methylation sites associated with SCLC-I are provided in Table 23.









TABLE 20







Additional methylation sites associated with the SCLC-A subtype











Methylation Site
Transcript_ID
Gene_Symbol
Gene_Region
Subtype





chr1: 958378
ENST00000477976.5
NOC2L
Exon
SCLC-A


chr1: 1348250
ENST00000378891.9
DVL1
Intron
SCLC-A


chr1: 3524391
ENST00000356575.9
MEGF6
Intron
SCLC-A


chr1: 3524397
ENST00000356575.9
MEGF6
Intron
SCLC-A


chr1: 3704686
ENST00000378295.9
TP73
Intron
SCLC-A


chr1: 4734864
ENST00000378191.5
AJAP1
Intron
SCLC-A


chr1: 5493929
ENST00000564261.1
NA
Exon
SCLC-A


chr1: 5493969
ENST00000564261.1
NA
Exon
SCLC-A


chr1: 6378290
ENST00000608083.5
ACOT7
Intron
SCLC-A


chr1: 6378309
ENST00000608083.5
ACOT7
Intron
SCLC-A


chr1: 6378318
ENST00000608083.5
ACOT7
Intron
SCLC-A


chr1: 6378319
ENST00000608083.5
ACOT7
Intron
SCLC-A


chr1: 7616559
ENST00000303635.12
CAMTA1
Intron
SCLC-A


chr1: 7649286
ENST00000303635.12
CAMTA1
Intron
SCLC-A


chr1: 8680968
ENST00000656437.1
RERE
Intron
SCLC-A


chr1: 8681121
ENST00000656437.1
RERE
Intron
SCLC-A


chr1: 10643731
ENST00000606802.1
NA
Intron
SCLC-A


chr1: 10643800
ENST00000606802.1
NA
Intron
SCLC-A


chr1: 10643801
ENST00000606802.1
NA
Intron
SCLC-A


chr1: 10643812
ENST00000606802.1
NA
Intron
SCLC-A


chr1: 10658338
ENST00000377022.8
CASZ1
Intron
SCLC-A


chr1: 10658341
ENST00000377022.8
CASZ1
Intron
SCLC-A


chr1: 10658374
ENST00000377022.8
CASZ1
Intron
SCLC-A


chr1: 10658375
ENST00000377022.8
CASZ1
Intron
SCLC-A


chr1: 10658433
ENST00000377022.8
CASZ1
Intron
SCLC-A


chr1: 10658451
ENST00000377022.8
CASZ1
Intron
SCLC-A


chr1: 10658452
ENST00000377022.8
CASZ1
Intron
SCLC-A


chr1: 10658548
ENST00000492173.1
CASZ1
Exon
SCLC-A


chr1: 10658572
ENST00000492173.1
CASZ1
Exon
SCLC-A


chr1: 10658839
ENST00000377022.8
CASZ1
Intron
SCLC-A


chr1: 10658845
ENST00000377022.8
CASZ1
Intron
SCLC-A


chr1: 10704614
ENST00000377022.8
CASZ1
Intron
SCLC-A


chr1: 10948170
ENST00000476357.1
C1orf127
Exon
SCLC-A


chr1: 10948349
ENST00000476357.1
C1orf127
Exon
SCLC-A


chr1: 10948642
ENST00000476357.1
C1orf127
Exon
SCLC-A


chr1: 11484596
ENST00000294484.7
DISP3
Intron
SCLC-A


chr1: 15735048
ENST00000453804.1
NA
Intron
SCLC-A


chr1: 15735060
ENST00000453804.1
NA
Intron
SCLC-A


chr1: 15765708
ENST00000502739.5
FBLIM1
Intron
SCLC-A


chr1: 15765709
ENST00000502739.5
FBLIM1
Intron
SCLC-A


chr1: 15765718
ENST00000502739.5
FBLIM1
Intron
SCLC-A


chr1: 15765815
ENST00000502739.5
FBLIM1
Intron
SCLC-A


chr1: 15941962
ENST00000462525.1
ZBTB17
Exon
SCLC-A


chr1: 15942041
ENST00000462525.1
ZBTB17
Exon
SCLC-A


chr1: 15942046
ENST00000462525.1
ZBTB17
Exon
SCLC-A


chr1: 15942052
ENST00000462525.1
ZBTB17
Exon
SCLC-A


chr1: 15942086
ENST00000462525.1
ZBTB17
Exon
SCLC-A


chr1: 18155744
ENST00000251296.4
IGSF21
Intron
SCLC-A


chr1: 18190698
ENST00000251296.4
IGSF21
Intron
SCLC-A


chr1: 18190842
ENST00000251296.4
IGSF21
Intron
SCLC-A


chr1: 18265745
ENST00000251296.4
IGSF21
Intron
SCLC-A


chr1: 18282300
ENST00000251296.4
IGSF21
Intron
SCLC-A


chr1: 18482634
ENST00000400664.2
KLHDC7A
Exon
SCLC-A


chr1: 18482653
ENST00000400664.2
KLHDC7A
Exon
SCLC-A


chr1: 18482654
ENST00000400664.2
KLHDC7A
Exon
SCLC-A


chr1: 18482655
ENST00000400664.2
KLHDC7A
Exon
SCLC-A


chr1: 18482656
ENST00000400664.2
KLHDC7A
Exon
SCLC-A


chr1: 18482672
ENST00000400664.2
KLHDC7A
Exon
SCLC-A


chr1: 18482678
ENST00000400664.2
KLHDC7A
Exon
SCLC-A


chr1: 18482679
ENST00000400664.2
KLHDC7A
Exon
SCLC-A


chr1: 18482691
ENST00000400664.2
KLHDC7A
Exon
SCLC-A


chr1: 18482702
ENST00000400664.2
KLHDC7A
Exon
SCLC-A


chr1: 21588078
ENST00000457706.1
NA
Intron
SCLC-A


chr1: 21603793
ENST00000611549.4
RAP1GAP
Exon
SCLC-A


chr1: 22853986
ENST00000544305.5
EPHB2
Intron
SCLC-A


chr1: 22853987
ENST00000544305.5
EPHB2
Intron
SCLC-A


chr1: 25771820
ENST00000496532.5
MAN1C1
Promoter
SCLC-A


chr1: 25771857
ENST00000496532.5
MAN1C1
Promoter
SCLC-A


chr1: 25771872
ENST00000496532.5
MAN1C1
Promoter
SCLC-A


chr1: 25771902
ENST00000496532.5
MAN1C1
Promoter
SCLC-A


chr1: 25810408
ENST00000354177.8
SELENON
Intron
SCLC-A


chr1: 26287066
ENST00000314675.11
UBXN11
Intron
SCLC-A


chr1: 26287108
ENST00000314675.11
UBXN11
Intron
SCLC-A


chr1: 26856854
ENST00000374142.9
ZDHHC18
Exon
SCLC-A


chr1: 28815683
ENST00000621425.1
OPRD1
Intron
SCLC-A


chr1: 28815743
ENST00000621425.1
OPRD1
Intron
SCLC-A


chr1: 28869196
ENST00000234961.7
OPRD1
Exon
SCLC-A


chr1: 31626876
ENST00000373705.1
HCRTR1
Intron
SCLC-A


chr1: 36846189
ENST00000373091.8
GRIK3
Intron
SCLC-A


chr1: 38004855
ENST00000485803.5
FHL3
Intron
SCLC-A


chr1: 38064302
ENST00000432922.5
NA
Intron
SCLC-A


chr1: 38136288
ENST00000641212.1
NA
Exon
SCLC-A


chr1: 39897235
ENST00000397332.2
MYCL
Exon
SCLC-A


chr1: 40314188
ENST00000372736.3
COL9A2
Intron
SCLC-A


chr1: 40314213
ENST00000372736.3
COL9A2
Intron
SCLC-A


chr1: 40314214
ENST00000372736.3
COL9A2
Intron
SCLC-A


chr1: 40314222
ENST00000372736.3
COL9A2
Intron
SCLC-A


chr1: 43997873
ENST00000372307.7
SLC6A9
Intron
SCLC-A


chr1: 43997890
ENST00000372307.7
SLC6A9
Intron
SCLC-A


chr1: 44289729
ENST00000456170.6
ERI3
Intron
SCLC-A


chr1: 45520656
ENST00000424390.1
PRDX1
Intron
SCLC-A


chr1: 45520711
ENST00000424390.1
PRDX1
Intron
SCLC-A


chr1: 45520719
ENST00000424390.1
PRDX1
Intron
SCLC-A


chr1: 50214781
ENST00000440897.1
NA
Intron
SCLC-A


chr1: 50214784
ENST00000440897.1
NA
Intron
SCLC-A


chr1: 50214848
ENST00000440897.1
NA
Intron
SCLC-A


chr1: 50214860
ENST00000440897.1
NA
Intron
SCLC-A


chr1: 50214888
ENST00000440897.1
NA
Intron
SCLC-A


chr1: 55050406
ENST00000302118.5
PCSK9
Intron
SCLC-A


chr1: 55063357
ENST00000302118.5
PCSK9
Intron
SCLC-A


chr1: 55063375
ENST00000302118.5
PCSK9
Exon
SCLC-A


chr1: 55063383
ENST00000302118.5
PCSK9
Exon
SCLC-A


chr1: 58922511
ENST00000665413.1
NA
Intron
SCLC-A


chr1: 58922515
ENST00000665413.1
NA
Intron
SCLC-A


chr1: 58922539
ENST00000665413.1
NA
Intron
SCLC-A


chr1: 58922540
ENST00000665413.1
NA
Intron
SCLC-A


chr1: 58922542
ENST00000665413.1
NA
Intron
SCLC-A


chr1: 58922543
ENST00000665413.1
NA
Intron
SCLC-A


chr1: 58922548
ENST00000665413.1
NA
Intron
SCLC-A


chr1: 58922549
ENST00000665413.1
NA
Intron
SCLC-A


chr1: 58922557
ENST00000665413.1
NA
Intron
SCLC-A


chr1: 60865294
ENST00000665290.1
LOC101926964
Intron
SCLC-A


chr1: 60897152
ENST00000371191.5
NFIA
Intron
SCLC-A


chr1: 60897198
ENST00000371191.5
NFIA
Intron
SCLC-A


chr1: 60903747
ENST00000371191.5
NFIA
Intron
SCLC-A


chr1: 60903756
ENST00000371191.5
NFIA
Intron
SCLC-A


chr1: 60903781
ENST00000371191.5
NFIA
Intron
SCLC-A


chr1: 60903785
ENST00000371191.5
NFIA
Intron
SCLC-A


chr1: 60903893
ENST00000371191.5
NFIA
Intron
SCLC-A


chr1: 65173967
ENST00000546702.5
AK4
Intron
SCLC-A


chr1: 110069330
ENST00000473429.5
STRIP1
Intron
SCLC-A


chr1: 110069428
ENST00000473429.5
STRIP1
Intron
SCLC-A


chr1: 110069452
ENST00000473429.5
STRIP1
Intron
SCLC-A


chr1: 110069456
ENST00000473429.5
STRIP1
Intron
SCLC-A


chr1: 110102148
ENST00000554808.1
LINC01397
Intron
SCLC-A


chr1: 110102161
ENST00000554808.1
LINC01397
Intron
SCLC-A


chr1: 110102162
ENST00000554808.1
LINC01397
Intron
SCLC-A


chr1: 110102262
ENST00000554808.1
LINC01397
Intron
SCLC-A


chr1: 112826812
ENST00000433505.5
LINC01356
Intron
SCLC-A


chr1: 147545284
ENST00000234739.8
BCL9
Intron
SCLC-A


chr1: 147545320
ENST00000234739.8
BCL9
Intron
SCLC-A


chr1: 161909783
ENST00000367942.4
ATF6
Intron
SCLC-A


chr1: 161909784
ENST00000367942.4
ATF6
Intron
SCLC-A


chr1: 161909813
ENST00000367942.4
ATF6
Intron
SCLC-A


chr1: 162373967
ENST00000431696.1
NOS1AP
Intron
SCLC-A


chr1: 162374123
ENST00000431696.1
NOS1AP
Intron
SCLC-A


chr1: 164638655
ENST00000340699.7
PBX1
Intron
SCLC-A


chr1: 164638678
ENST00000340699.7
PBX1
Intron
SCLC-A


chr1: 164638679
ENST00000340699.7
PBX1
Intron
SCLC-A


chr1: 164638728
ENST00000340699.7
PBX1
Intron
SCLC-A


chr1: 164638729
ENST00000340699.7
PBX1
Intron
SCLC-A


chr1: 164638734
ENST00000340699.7
PBX1
Intron
SCLC-A


chr1: 164638735
ENST00000340699.7
PBX1
Intron
SCLC-A


chr1: 164638825
ENST00000340699.7
PBX1
Intron
SCLC-A


chr1: 164797338
ENST00000558796.2
NA
Intron
SCLC-A


chr1: 180173996
ENST00000367602.8
QSOX1
Intron
SCLC-A


chr1: 180928484
ENST00000367587.1
KIAA1614
Exon
SCLC-A


chr1: 180928548
ENST00000367587.1
KIAA1614
Exon
SCLC-A


chr1: 182236168
ENST00000449842.2
LINC01344
Intron
SCLC-A


chr1: 182236190
ENST00000449842.2
LINC01344
Intron
SCLC-A


chr1: 202199385
ENST00000367278.7
LGR6
Intron
SCLC-A


chr1: 202637540
ENST00000367268.5
SYT2
Intron
SCLC-A


chr1: 202637566
ENST00000367268.5
SYT2
Intron
SCLC-A


chr1: 202637656
ENST00000367268.5
SYT2
Intron
SCLC-A


chr1: 202637657
ENST00000367268.5
SYT2
Intron
SCLC-A


chr1: 203506933
ENST00000367222.7
OPTC
Intron
SCLC-A


chr1: 204104288
ENST00000530882.1
SOX13
Intron
SCLC-A


chr1: 204447561
ENST00000367187.7
PIK3C2B
Exon
SCLC-A


chr1: 204447662
ENST00000367187.7
PIK3C2B
Intron
SCLC-A


chr1: 204684469
ENST00000367177.4
LRRN2
Intron
SCLC-A


chr1: 204684497
ENST00000367177.4
LRRN2
Intron
SCLC-A


chr1: 204684501
ENST00000367177.4
LRRN2
Intron
SCLC-A


chr1: 204684534
ENST00000367177.4
LRRN2
Intron
SCLC-A


chr1: 204684542
ENST00000367177.4
LRRN2
Intron
SCLC-A


chr1: 204684566
ENST00000367177.4
LRRN2
Intron
SCLC-A


chr1: 204684591
ENST00000367177.4
LRRN2
Intron
SCLC-A


chr1: 204684592
ENST00000367177.4
LRRN2
Intron
SCLC-A


chr1: 204684660
ENST00000367177.4
LRRN2
Intron
SCLC-A


chr1: 204684666
ENST00000367177.4
LRRN2
Intron
SCLC-A


chr1: 204968154
ENST00000339876.10
NFASC
Intron
SCLC-A


chr1: 204968321
ENST00000504149.1
NFASC
Exon
SCLC-A


chr1: 205240223
ENST00000358024.8
TMCC2
Intron
SCLC-A


chr1: 206490686
ENST00000581977.7
IKBKE
Intron
SCLC-A


chr1: 206490693
ENST00000581977.7
IKBKE
Intron
SCLC-A


chr1: 206490876
ENST00000581977.7
IKBKE
Intron
SCLC-A


chr1: 206490877
ENST00000581977.7
IKBKE
Intron
SCLC-A


chr1: 206490920
ENST00000581977.7
IKBKE
Intron
SCLC-A


chr1: 206490962
ENST00000581977.7
IKBKE
Intron
SCLC-A


chr1: 207873634
ENST00000637970.1
MIR29B2CHG
Intron
SCLC-A


chr1: 212979917
ENST00000366966.6
VASH2
Intron
SCLC-A


chr1: 212980023
ENST00000366966.6
VASH2
Intron
SCLC-A


chr1: 214551061
ENST00000366956.10
PTPN14
Intron
SCLC-A


chr1: 214551098
ENST00000366956.10
PTPN14
Intron
SCLC-A


chr1: 214551122
ENST00000366956.10
PTPN14
Intron
SCLC-A


chr1: 226588954
ENST00000366788.8
STUM
Intron
SCLC-A


chr1: 226638084
ENST00000272117.7
ITPKB
Intron
SCLC-A


chr1: 226653615
ENST00000272117.7
ITPKB
Intron
SCLC-A


chr1: 234235838
ENST00000366618.8
SLC35F3
Intron
SCLC-A


chr1: 245609842
ENST00000407071.7
KIF26B
Intron
SCLC-A


chr1: 245609882
ENST00000407071.7
KIF26B
Intron
SCLC-A


chr1: 245609932
ENST00000407071.7
KIF26B
Intron
SCLC-A


chr1: 246101776
ENST00000630181.2
SMYD3
Intron
SCLC-A


chr10: 1650783
ENST00000381312.6
ADARB2
Intron
SCLC-A


chr10: 1650884
ENST00000381312.6
ADARB2
Intron
SCLC-A


chr10: 1652303
ENST00000381312.6
ADARB2
Intron
SCLC-A


chr10: 1652318
ENST00000381312.6
ADARB2
Intron
SCLC-A


chr10: 1652368
ENST00000381312.6
ADARB2
Intron
SCLC-A


chr10: 1652396
ENST00000381312.6
ADARB2
Intron
SCLC-A


chr10: 3045918
ENST00000658425.1
NA
Intron
SCLC-A


chr10: 3045932
ENST00000658425.1
NA
Intron
SCLC-A


chr10: 14605132
ENST00000181796.6
FAM107B
Intron
SCLC-A


chr10: 14605133
ENST00000181796.6
FAM107B
Intron
SCLC-A


chr10: 14605156
ENST00000181796.6
FAM107B
Intron
SCLC-A


chr10: 16684672
ENST00000377921.7
RSU1
Intron
SCLC-A


chr10: 23960207
ENST00000376462.5
KIAA1217
Intron
SCLC-A


chr10: 24187920
ENST00000376462.5
KIAA1217
Intron
SCLC-A


chr10: 24278372
ENST00000376462.5
KIAA1217
Intron
SCLC-A


chr10: 24293969
ENST00000376462.5
KIAA1217
Intron
SCLC-A


chr10: 24294010
ENST00000376462.5
KIAA1217
Intron
SCLC-A


chr10: 34795148
ENST00000545260.5
PARD3
Intron
SCLC-A


chr10: 43082844
ENST00000498820.5
RET
Intron
SCLC-A


chr10: 51123452
ENST00000401604.8
PRKG1
Intron
SCLC-A


chr10: 51123579
ENST00000401604.8
PRKG1
Intron
SCLC-A


chr10: 71225616
ENST00000335350.10
UNC5B
Intron
SCLC-A


chr10: 71225620
ENST00000335350.10
UNC5B
Intron
SCLC-A


chr10: 71279282
ENST00000335350.10
UNC5B
Intron
SCLC-A


chr10: 71279303
ENST00000335350.10
UNC5B
Intron
SCLC-A


chr10: 71279304
ENST00000335350.10
UNC5B
Intron
SCLC-A


chr10: 71279323
ENST00000335350.10
UNC5B
Intron
SCLC-A


chr10: 71279324
ENST00000335350.10
UNC5B
Intron
SCLC-A


chr10: 71279401
ENST00000335350.10
UNC5B
Intron
SCLC-A


chr10: 71279426
ENST00000335350.10
UNC5B
Intron
SCLC-A


chr10: 71279427
ENST00000335350.10
UNC5B
Intron
SCLC-A


chr10: 71279454
ENST00000335350.10
UNC5B
Intron
SCLC-A


chr10: 71965349
ENST00000373115.5
CHST3
Intron
SCLC-A


chr10: 71965350
ENST00000373115.5
CHST3
Intron
SCLC-A


chr10: 71965369
ENST00000373115.5
CHST3
Intron
SCLC-A


chr10: 71965370
ENST00000373115.5
CHST3
Intron
SCLC-A


chr10: 71965378
ENST00000373115.5
CHST3
Intron
SCLC-A


chr10: 71965400
ENST00000373115.5
CHST3
Intron
SCLC-A


chr10: 71965440
ENST00000373115.5
CHST3
Intron
SCLC-A


chr10: 71965474
ENST00000373115.5
CHST3
Intron
SCLC-A


chr10: 74133949
ENST00000355264.8
AP3M1
Intron
SCLC-A


chr10: 74134045
ENST00000355264.8
AP3M1
Exon
SCLC-A


chr10: 74134046
ENST00000355264.8
AP3M1
Exon
SCLC-A


chr10: 74134105
ENST00000355264.8
AP3M1
Exon
SCLC-A


chr10: 74134108
ENST00000355264.8
AP3M1
Exon
SCLC-A


chr10: 78963893
ENST00000456353.5
ZMIZ1-AS1
Intron
SCLC-A


chr10: 78963937
ENST00000456353.5
ZMIZ1-AS1
Intron
SCLC-A


chr10: 86672720
ENST00000429277.6
LDB3
Intron
SCLC-A


chr10: 95355950
ENST00000371227.8
SORBS1
Intron
SCLC-A


chr10: 95356062
ENST00000371227.8
SORBS1
Intron
SCLC-A


chr10: 99167103
ENST00000628193.2
HPSE2
Intron
SCLC-A


chr10: 99879859
ENST00000543621.6
DNMBP
Exon
SCLC-A


chr10: 101242381
ENST00000434878.1
NA
Intron
SCLC-A


chr10: 102294542
ENST00000369983.3
GBF1
Intron
SCLC-A


chr10: 102294602
ENST00000369983.3
GBF1
Intron
SCLC-A


chr10: 112952124
ENST00000534894.5
TCF7L2
Intron
SCLC-A


chr10: 112952316
ENST00000534894.5
TCF7L2
Intron
SCLC-A


chr10: 112952366
ENST00000534894.5
TCF7L2
Intron
SCLC-A


chr10: 112952389
ENST00000534894.5
TCF7L2
Intron
SCLC-A


chr10: 112952520
ENST00000534894.5
TCF7L2
Intron
SCLC-A


chr10: 116275072
ENST00000648277.1
NA
Exon
SCLC-A


chr10: 116275113
ENST00000648277.1
NA
Exon
SCLC-A


chr10: 118809054
ENST00000663084.1
NA
Intron
SCLC-A


chr10: 118809074
ENST00000663084.1
NA
Intron
SCLC-A


chr10: 119282663
ENST00000392870.3
GRK5
Intron
SCLC-A


chr10: 121580580
ENST00000356226.8
FGFR2
Intron
SCLC-A


chr10: 121580749
ENST00000356226.8
FGFR2
Intron
SCLC-A


chr10: 124482462
ENST00000368842.10
LHPP
Intron
SCLC-A


chr10: 124482496
ENST00000368842.10
LHPP
Intron
SCLC-A


chr10: 124482554
ENST00000368842.10
LHPP
Intron
SCLC-A


chr10: 127424585
ENST00000280333.9
DOCK1
Intron
SCLC-A


chr10: 127424596
ENST00000280333.9
DOCK1
Intron
SCLC-A


chr10: 127424597
ENST00000280333.9
DOCK1
Intron
SCLC-A


chr10: 127424611
ENST00000280333.9
DOCK1
Intron
SCLC-A


chr10: 127424612
ENST00000280333.9
DOCK1
Intron
SCLC-A


chr10: 127424671
ENST00000280333.9
DOCK1
Intron
SCLC-A


chr10: 127424672
ENST00000280333.9
DOCK1
Intron
SCLC-A


chr10: 127424673
ENST00000280333.9
DOCK1
Intron
SCLC-A


chr10: 127424674
ENST00000280333.9
DOCK1
Intron
SCLC-A


chr10: 127424684
ENST00000280333.9
DOCK1
Intron
SCLC-A


chr10: 129849527
ENST00000368648.7
EBF3
Intron
SCLC-A


chr10: 129849536
ENST00000368648.7
EBF3
Intron
SCLC-A


chr10: 129849548
ENST00000368648.7
EBF3
Intron
SCLC-A


chr10: 129849583
ENST00000368648.7
EBF3
Intron
SCLC-A


chr10: 129849589
ENST00000368648.7
EBF3
Intron
SCLC-A


chr10: 129849601
ENST00000368648.7
EBF3
Intron
SCLC-A


chr10: 129849604
ENST00000368648.7
EBF3
Intron
SCLC-A


chr10: 129849607
ENST00000368648.7
EBF3
Intron
SCLC-A


chr10: 132972142
ENST00000461291.2
LINC01168
Exon
SCLC-A


chr10: 132972143
ENST00000461291.2
LINC01168
Exon
SCLC-A


chr10: 133310352
ENST00000482278.5
TUBGCP2
Intron
SCLC-A


chr10: 133310353
ENST00000482278.5
TUBGCP2
Intron
SCLC-A


chr11: 888570
ENST00000526714.5
CHID1
Intron
SCLC-A


chr11: 888640
ENST00000526714.5
CHID1
Intron
SCLC-A


chr11: 1455421
ENST00000308219.13
BRSK2
Intron
SCLC-A


chr11: 2718002
ENST00000155840.11
KCNQ1
Intron
SCLC-A


chr11: 8775439
ENST00000526057.5
DENND2B
Intron
SCLC-A


chr11: 17449180
ENST00000645744.1
ABCC8
Intron
SCLC-A


chr11: 19692207
ENST00000360655.8
NAV2
Intron
SCLC-A


chr11: 19692236
ENST00000360655.8
NAV2
Intron
SCLC-A


chr11: 19832407
ENST00000360655.8
NAV2
Intron
SCLC-A


chr11: 19832412
ENST00000360655.8
NAV2
Intron
SCLC-A


chr11: 19832444
ENST00000360655.8
NAV2
Intron
SCLC-A


chr11: 19832445
ENST00000360655.8
NAV2
Intron
SCLC-A


chr11: 19832522
ENST00000360655.8
NAV2
Exon
SCLC-A


chr11: 19832523
ENST00000360655.8
NAV2
Exon
SCLC-A


chr11: 19832532
ENST00000360655.8
NAV2
Exon
SCLC-A


chr11: 19832570
ENST00000360655.8
NAV2
Exon
SCLC-A


chr11: 19832571
ENST00000360655.8
NAV2
Exon
SCLC-A


chr11: 19832660
ENST00000360655.8
NAV2
Intron
SCLC-A


chr11: 22338216
ENST00000263160.4
SLC17A6
Promoter
SCLC-A


chr11: 22338217
ENST00000263160.4
SLC17A6
Promoter
SCLC-A


chr11: 22338234
ENST00000263160.4
SLC17A6
Promoter
SCLC-A


chr11: 22338247
ENST00000263160.4
SLC17A6
Promoter
SCLC-A


chr11: 22338248
ENST00000263160.4
SLC17A6
Promoter
SCLC-A


chr11: 32092239
ENST00000530348.5
RCN1
Intron
SCLC-A


chr11: 32092256
ENST00000530348.5
RCN1
Intron
SCLC-A


chr11: 32092264
ENST00000530348.5
RCN1
Intron
SCLC-A


chr11: 32092281
ENST00000530348.5
RCN1
Intron
SCLC-A


chr11: 32434969
ENST00000640146.2
WT1
Promoter
SCLC-A


chr11: 32435054
ENST00000640146.2
WT1
Promoter
SCLC-A


chr11: 32435081
ENST00000640146.2
WT1
Promoter
SCLC-A


chr11: 33645875
ENST00000658780.1
KIAA1549L
Exon
SCLC-A


chr11: 33645888
ENST00000658780.1
KIAA1549L
Exon
SCLC-A


chr11: 33645905
ENST00000658780.1
KIAA1549L
Exon
SCLC-A


chr11: 33890508
ENST00000257818.3
LMO2
Intron
SCLC-A


chr11: 33890510
ENST00000257818.3
LMO2
Intron
SCLC-A


chr11: 34345926
ENST00000435224.3
ABTB2
Intron
SCLC-A


chr11: 34345939
ENST00000435224.3
ABTB2
Intron
SCLC-A


chr11: 34502665
ENST00000429939.6
ELF5
Intron
SCLC-A


chr11: 44593266
ENST00000529277.5
CD82
Intron
SCLC-A


chr11: 44593342
ENST00000529277.5
CD82
Intron
SCLC-A


chr11: 44593415
ENST00000529277.5
CD82
Intron
SCLC-A


chr11: 44593416
ENST00000529277.5
CD82
Intron
SCLC-A


chr11: 44593418
ENST00000529277.5
CD82
Intron
SCLC-A


chr11: 44593458
ENST00000529277.5
CD82
Intron
SCLC-A


chr11: 46273915
ENST00000527239.1
NA
Intron
SCLC-A


chr11: 46273916
ENST00000527239.1
NA
Intron
SCLC-A


chr11: 46894657
ENST00000378623.6
LRP4
Exon
SCLC-A


chr11: 46894691
ENST00000378623.6
LRP4
Exon
SCLC-A


chr11: 46894693
ENST00000378623.6
LRP4
Exon
SCLC-A


chr11: 46894696
ENST00000378623.6
LRP4
Exon
SCLC-A


chr11: 46894760
ENST00000378623.6
LRP4
Exon
SCLC-A


chr11: 46918851
ENST00000378623.6
LRP4
Promoter
SCLC-A


chr11: 46918857
ENST00000378623.6
LRP4
Promoter
SCLC-A


chr11: 46918928
ENST00000378623.6
LRP4
Promoter
SCLC-A


chr11: 60375860
ENST00000532756.1
MS4A6E
Intron
SCLC-A


chr11: 64146424
ENST00000545464.5
MACROD1
Intron
SCLC-A


chr11: 64146425
ENST00000545464.5
MACROD1
Intron
SCLC-A


chr11: 64146430
ENST00000545464.5
MACROD1
Intron
SCLC-A


chr11: 64146431
ENST00000545464.5
MACROD1
Intron
SCLC-A


chr11: 64146454
ENST00000545464.5
MACROD1
Intron
SCLC-A


chr11: 64146460
ENST00000545464.5
MACROD1
Intron
SCLC-A


chr11: 65552712
ENST00000528966.5
LTBP3
Promoter
SCLC-A


chr11: 65552874
ENST00000529764.1
LTBP3
Promoter
SCLC-A


chr11: 65552875
ENST00000529764.1
LTBP3
Promoter
SCLC-A


chr11: 68010316
ENST00000614849.4
ALDH3B1
Intron
SCLC-A


chr11: 68828883
ENST00000561996.1
CPT1A
Intron
SCLC-A


chr11: 68829295
ENST00000561996.1
CPT1A
Intron
SCLC-A


chr11: 70828728
ENST00000601538.5
SHANK2
Intron
SCLC-A


chr11: 70828944
ENST00000601538.5
SHANK2
Intron
SCLC-A


chr11: 71153151
ENST00000601538.5
SHANK2
Intron
SCLC-A


chr11: 71153180
ENST00000601538.5
SHANK2
Intron
SCLC-A


chr11: 75339869
ENST00000420843.7
ARRB1
Intron
SCLC-A


chr11: 75339900
ENST00000420843.7
ARRB1
Intron
SCLC-A


chr11: 75339977
ENST00000420843.7
ARRB1
Intron
SCLC-A


chr11: 75339978
ENST00000420843.7
ARRB1
Intron
SCLC-A


chr11: 107176910
ENST00000526512.1
NA
Exon
SCLC-A


chr11: 107176925
ENST00000526512.1
NA
Exon
SCLC-A


chr11: 119976142
ENST00000664971.1
NA
Exon
SCLC-A


chr11: 119976171
ENST00000664971.1
NA
Intron
SCLC-A


chr11: 119976172
ENST00000664971.1
NA
Intron
SCLC-A


chr11: 119976214
ENST00000664971.1
NA
Intron
SCLC-A


chr11: 121111282
ENST00000645041.1
TBCEL
Intron
SCLC-A


chr11: 126356252
ENST00000629441.1
GSEC
Promoter
SCLC-A


chr11: 126356902
ENST00000227495.10
ST3GAL4
Intron
SCLC-A


chr11: 126585524
ENST00000548204.1
NA
Intron
SCLC-A


chr11: 126585526
ENST00000548204.1
NA
Intron
SCLC-A


chr11: 126852951
ENST00000525144.7
KIRREL3
Intron
SCLC-A


chr11: 126852952
ENST00000525144.7
KIRREL3
Intron
SCLC-A


chr11: 126852977
ENST00000525144.7
KIRREL3
Intron
SCLC-A


chr11: 128720829
ENST00000608303.5
FLI1
Intron
SCLC-A


chr11: 128726019
ENST00000608303.5
FLI1
Intron
SCLC-A


chr12: 168200
ENST00000538872.6
IQSEC3
Intron
SCLC-A


chr12: 543077
ENST00000266383.10
B4GALNT3
Intron
SCLC-A


chr12: 1500545
ENST00000515614.3
LINC00942
Exon
SCLC-A


chr12: 2846128
ENST00000643039.1
ITFG2
Intron
SCLC-A


chr12: 2846129
ENST00000643039.1
ITFG2
Intron
SCLC-A


chr12: 3077894
ENST00000537971.5
TSPAN9
Intron
SCLC-A


chr12: 3077928
ENST00000537971.5
TSPAN9
Intron
SCLC-A


chr12: 6340746
ENST00000534885.5
TNFRSF1A
Intron
SCLC-A


chr12: 6633709
ENST00000329858.9
LPAR5
Intron
SCLC-A


chr12: 21829391
ENST00000539874.1
NA
Intron
SCLC-A


chr12: 21829497
ENST00000539874.1
NA
Intron
SCLC-A


chr12: 21841579
ENST00000539874.1
NA
Intron
SCLC-A


chr12: 21841649
ENST00000539874.1
NA
Intron
SCLC-A


chr12: 21868362
ENST00000539874.1
NA
Intron
SCLC-A


chr12: 30988328
ENST00000546076.5
TSPAN11
Intron
SCLC-A


chr12: 42479753
ENST00000639958.1
PRICKLE1
Intron
SCLC-A


chr12: 58742170
ENST00000546977.5
LOC100506869
Intron
SCLC-A


chr12: 97465122
ENST00000538559.6
RMST
Intron
SCLC-A


chr12: 97465248
ENST00000538559.6
RMST
Intron
SCLC-A


chr12: 97465272
ENST00000538559.6
RMST
Intron
SCLC-A


chr12: 97465282
ENST00000538559.6
RMST
Intron
SCLC-A


chr12: 97465283
ENST00000538559.6
RMST
Intron
SCLC-A


chr12: 108446979
ENST00000502160.6
LINC01498
Intron
SCLC-A


chr12: 109723834
ENST00000538780.1
FAM222A
Intron
SCLC-A


chr12: 119179398
ENST00000541798.1
HSPB8
Promoter
SCLC-A


chr12: 119179459
ENST00000541798.1
HSPB8
Promoter
SCLC-A


chr12: 119179460
ENST00000541798.1
HSPB8
Promoter
SCLC-A


chr12: 119179509
ENST00000541798.1
HSPB8
Promoter
SCLC-A


chr12: 121790098
ENST00000267205.7
RHOF
Intron
SCLC-A


chr12: 121793404
ENST00000546227.5
RHOF
Intron
SCLC-A


chr12: 124259751
ENST00000389727.8
ZNF664-RFLNA
Intron
SCLC-A


chr12: 124259755
ENST00000389727.8
ZNF664-RFLNA
Intron
SCLC-A


chr12: 124259756
ENST00000389727.8
ZNF664-RFLNA
Intron
SCLC-A


chr12: 124259764
ENST00000389727.8
ZNF664-RFLNA
Intron
SCLC-A


chr12: 124259765
ENST00000389727.8
ZNF664-RFLNA
Intron
SCLC-A


chr12: 124259769
ENST00000389727.8
ZNF664-RFLNA
Intron
SCLC-A


chr12: 124259805
ENST00000389727.8
ZNF664-RFLNA
Intron
SCLC-A


chr12: 124259869
ENST00000389727.8
ZNF664-RFLNA
Intron
SCLC-A


chr12: 124259875
ENST00000389727.8
ZNF664-RFLNA
Intron
SCLC-A


chr12: 124289987
ENST00000389727.8
ZNF664-RFLNA
Intron
SCLC-A


chr12: 124290024
ENST00000389727.8
ZNF664-RFLNA
Intron
SCLC-A


chr12: 124290027
ENST00000389727.8
ZNF664-RFLNA
Intron
SCLC-A


chr12: 130460794
ENST00000261655.8
RIMBP2
Intron
SCLC-A


chr12: 130460795
ENST00000261655.8
RIMBP2
Intron
SCLC-A


chr12: 130460796
ENST00000261655.8
RIMBP2
Intron
SCLC-A


chr12: 130461043
ENST00000261655.8
RIMBP2
Intron
SCLC-A


chr12: 130461044
ENST00000261655.8
RIMBP2
Intron
SCLC-A


chr12: 130461173
ENST00000261655.8
RIMBP2
Intron
SCLC-A


chr13: 25964027
ENST00000381655.7
ATP8A2
Intron
SCLC-A


chr13: 25964055
ENST00000381655.7
ATP8A2
Intron
SCLC-A


chr13: 27961367
ENST00000381020.8
CDX2
Exon
SCLC-A


chr13: 29567470
ENST00000380752.10
SLC7A1
Intron
SCLC-A


chr13: 29567546
ENST00000380752.10
SLC7A1
Intron
SCLC-A


chr13: 39600949
ENST00000648377.1
LHFPL6
Exon
SCLC-A


chr13: 39601041
ENST00000648377.1
LHFPL6
Exon
SCLC-A


chr13: 39601042
ENST00000648377.1
LHFPL6
Exon
SCLC-A


chr13: 39601075
ENST00000648377.1
LHFPL6
Exon
SCLC-A


chr13: 50129918
ENST00000476738.5
DLEU1
Intron
SCLC-A


chr13: 50129964
ENST00000476738.5
DLEU1
Intron
SCLC-A


chr13: 50129976
ENST00000476738.5
DLEU1
Intron
SCLC-A


chr13: 50130078
ENST00000476738.5
DLEU1
Intron
SCLC-A


chr13: 94968694
ENST00000669430.1
NA
Intron
SCLC-A


chr13: 94968800
ENST00000669430.1
NA
Intron
SCLC-A


chr13: 94968807
ENST00000669430.1
NA
Intron
SCLC-A


chr13: 94968841
ENST00000669430.1
NA
Intron
SCLC-A


chr13: 94968846
ENST00000669430.1
NA
Intron
SCLC-A


chr13: 94968880
ENST00000669430.1
NA
Intron
SCLC-A


chr13: 94968943
ENST00000669430.1
NA
Intron
SCLC-A


chr13: 94968944
ENST00000669430.1
NA
Intron
SCLC-A


chr13: 94968987
ENST00000669430.1
NA
Intron
SCLC-A


chr13: 98214022
ENST00000595437.5
FARP1
Intron
SCLC-A


chr13: 98214053
ENST00000595437.5
FARP1
Intron
SCLC-A


chr13: 98214104
ENST00000595437.5
FARP1
Intron
SCLC-A


chr13: 98214113
ENST00000595437.5
FARP1
Intron
SCLC-A


chr13: 98214154
ENST00000595437.5
FARP1
Intron
SCLC-A


chr13: 98214201
ENST00000595437.5
FARP1
Intron
SCLC-A


chr13: 98214220
ENST00000595437.5
FARP1
Intron
SCLC-A


chr13: 98214229
ENST00000595437.5
FARP1
Intron
SCLC-A


chr13: 107868214
ENST00000375915.4
FAM155A
Promoter
SCLC-A


chr13: 111598391
ENST00000375713.1
NA
Intron
SCLC-A


chr13: 111598398
ENST00000375713.1
NA
Intron
SCLC-A


chr13: 114161911
ENST00000643687.1
NA
Intron
SCLC-A


chr13: 114161926
ENST00000643687.1
NA
Intron
SCLC-A


chr14: 70742303
ENST00000611979.4
MAP3K9
Intron
SCLC-A


chr14: 74917011
ENST00000555009.5
RPS6KL1
Intron
SCLC-A


chr14: 76261732
ENST00000554225.1
NA
Intron
SCLC-A


chr14: 76261754
ENST00000554225.1
NA
Intron
SCLC-A


chr14: 76396981
ENST00000512784.6
ESRRB
Intron
SCLC-A


chr14: 76397007
ENST00000512784.6
ESRRB
Intron
SCLC-A


chr14: 90600821
ENST00000328459.11
TTC7B
Intron
SCLC-A


chr14: 90700943
ENST00000328459.11
TTC7B
Intron
SCLC-A


chr14: 91895601
ENST00000267620.14
FBLN5
Intron
SCLC-A


chr14: 91895602
ENST00000267620.14
FBLN5
Intron
SCLC-A


chr14: 93737704
ENST00000393143.5
PRIMA1
Intron
SCLC-A


chr14: 93737727
ENST00000393143.5
PRIMA1
Intron
SCLC-A


chr14: 93962999
ENST00000556337.1
ASB2
Intron
SCLC-A


chr14: 93963010
ENST00000556337.1
ASB2
Intron
SCLC-A


chr14: 95259420
ENST00000298912.9
CLMN
Intron
SCLC-A


chr14: 95877410
ENST00000504119.1
TUNAR
Intron
SCLC-A


chr14: 99760240
ENST00000554479.5
EML1
Intron
SCLC-A


chr14: 100903298
ENST00000637474.1
MEG8
Intron
SCLC-A


chr14: 102001006
ENST00000643684.1
DYNC1H1
Exon
SCLC-A


chr15: 28884288
ENST00000669290.1
NA
Intron
SCLC-A


chr15: 28884378
ENST00000561069.5
APBA2
Promoter
SCLC-A


chr15: 34580533
ENST00000569100.5
GOLGA8B
Intron
SCLC-A


chr15: 60398693
ENST00000557904.5
ANXA2
Intron
SCLC-A


chr15: 60398722
ENST00000557904.5
ANXA2
Intron
SCLC-A


chr15: 60398724
ENST00000557904.5
ANXA2
Intron
SCLC-A


chr15: 60398749
ENST00000557904.5
ANXA2
Intron
SCLC-A


chr15: 65271083
ENST00000444347.2
PARP16
Intron
SCLC-A


chr15: 74826644
ENST00000564823.1
CPLX3
Exon
SCLC-A


chr15: 78649932
ENST00000560511.5
CHRNB4
Intron
SCLC-A


chr15: 80559650
ENST00000303329.9
ARNT2
Intron
SCLC-A


chr15: 81271331
ENST00000560241.5
IL16
Intron
SCLC-A


chr15: 89647015
ENST00000394412.8
KIF7
Exon
SCLC-A


chr15: 89815295
ENST00000300060.7
ANPEP
Promoter
SCLC-A


chr15: 90660767
ENST00000559531.1
CRTC3-AS1
Intron
SCLC-A


chr15: 96321658
ENST00000502125.6
NR2F2-AS1
Intron
SCLC-A


chr15: 98998036
ENST00000559468.1
NA
Intron
SCLC-A


chr15: 100111195
ENST00000268070.9
ADAMTS17
Intron
SCLC-A


chr16: 71901
ENST00000450643.5
RHBDF1
Intron
SCLC-A


chr16: 71908
ENST00000450643.5
RHBDF1
Intron
SCLC-A


chr16: 301937
ENST00000461023.5
AXIN1
Intron
SCLC-A


chr16: 301947
ENST00000461023.5
AXIN1
Intron
SCLC-A


chr16: 528881
ENST00000219611.7
CAPN15
Intron
SCLC-A


chr16: 528917
ENST00000219611.7
CAPN15
Intron
SCLC-A


chr16: 528918
ENST00000219611.7
CAPN15
Intron
SCLC-A


chr16: 528931
ENST00000219611.7
CAPN15
Intron
SCLC-A


chr16: 528932
ENST00000219611.7
CAPN15
Intron
SCLC-A


chr16: 629494
ENST00000573440.1
NA
Exon
SCLC-A


chr16: 629543
ENST00000573440.1
NA
Exon
SCLC-A


chr16: 629643
ENST00000573440.1
NA
Exon
SCLC-A


chr16: 629796
ENST00000573440.1
NA
Exon
SCLC-A


chr16: 629918
ENST00000573440.1
NA
Exon
SCLC-A


chr16: 1158479
ENST00000638323.1
CACNA1H
Intron
SCLC-A


chr16: 1158560
ENST00000638323.1
CACNA1H
Intron
SCLC-A


chr16: 1158565
ENST00000638323.1
CACNA1H
Intron
SCLC-A


chr16: 1158758
ENST00000638323.1
CACNA1H
Intron
SCLC-A


chr16: 1158983
ENST00000638323.1
CACNA1H
Intron
SCLC-A


chr16: 1159004
ENST00000638323.1
CACNA1H
Intron
SCLC-A


chr16: 1159245
ENST00000638323.1
CACNA1H
Intron
SCLC-A


chr16: 1159298
ENST00000638323.1
CACNA1H
Intron
SCLC-A


chr16: 2283053
ENST00000569062.1
ABCA3
Intron
SCLC-A


chr16: 2283141
ENST00000569062.1
ABCA3
Intron
SCLC-A


chr16: 2283155
ENST00000569062.1
ABCA3
Intron
SCLC-A


chr16: 2283202
ENST00000569062.1
ABCA3
Exon
SCLC-A


chr16: 4260046
ENST00000204517.11
TFAP4
Intron
SCLC-A


chr16: 4260193
ENST00000575320.1
TFAP4
Exon
SCLC-A


chr16: 4260231
ENST00000575320.1
TFAP4
Exon
SCLC-A


chr16: 4260760
ENST00000574639.1
TFAP4
Intron
SCLC-A


chr16: 4892618
ENST00000592772.1
PPL
Intron
SCLC-A


chr16: 6189354
ENST00000569895.3
RBFOX1
Intron
SCLC-A


chr16: 6189356
ENST00000569895.3
RBFOX1
Intron
SCLC-A


chr16: 8776423
ENST00000268251.13
ABAT
Exon
SCLC-A


chr16: 11349782
ENST00000649869.1
NA
Intron
SCLC-A


chr16: 11349931
ENST00000649869.1
NA
Intron
SCLC-A


chr16: 11387124
ENST00000599216.5
LOC400499
Exon
SCLC-A


chr16: 11387125
ENST00000599216.5
LOC400499
Exon
SCLC-A


chr16: 11387135
ENST00000599216.5
LOC400499
Exon
SCLC-A


chr16: 11387138
ENST00000599216.5
LOC400499
Exon
SCLC-A


chr16: 11411119
ENST00000596416.1
LOC400499
Intron
SCLC-A


chr16: 11609545
ENST00000574848.5
LITAF
Intron
SCLC-A


chr16: 11609559
ENST00000574848.5
LITAF
Intron
SCLC-A


chr16: 11613760
ENST00000574848.5
LITAF
Intron
SCLC-A


chr16: 16067336
ENST00000399408.6
ABCC1
Intron
SCLC-A


chr16: 16067355
ENST00000399408.6
ABCC1
Intron
SCLC-A


chr16: 16067356
ENST00000399408.6
ABCC1
Intron
SCLC-A


chr16: 16101762
ENST00000399410.8
ABCC1
Intron
SCLC-A


chr16: 16101824
ENST00000399410.8
ABCC1
Intron
SCLC-A


chr16: 21511849
ENST00000522841.6
SMG1P3
Intron
SCLC-A


chr16: 21514060
ENST00000522841.6
SMG1P3
Intron
SCLC-A


chr16: 21514076
ENST00000522841.6
SMG1P3
Intron
SCLC-A


chr16: 21514077
ENST00000522841.6
SMG1P3
Intron
SCLC-A


chr16: 21514208
ENST00000522841.6
SMG1P3
Intron
SCLC-A


chr16: 53983658
ENST00000636992.1
FTO
Intron
SCLC-A


chr16: 54054484
ENST00000471389.6
FTO
Intron
SCLC-A


chr16: 54054552
ENST00000471389.6
FTO
Intron
SCLC-A


chr16: 54054572
ENST00000471389.6
FTO
Intron
SCLC-A


chr16: 56961212
ENST00000379780.6
CETP
Promoter
SCLC-A


chr16: 57115437
ENST00000290776.13
CPNE2
Intron
SCLC-A


chr16: 57475091
ENST00000566936.5
DOK4
Intron
SCLC-A


chr16: 57863783
ENST00000563028.1
KIFC3
Promoter
SCLC-A


chr16: 57863784
ENST00000563028.1
KIFC3
Promoter
SCLC-A


chr16: 58474357
ENST00000568999.5
NDRG4
Intron
SCLC-A


chr16: 64947737
ENST00000394156.7
CDH11
Exon
SCLC-A


chr16: 64997037
ENST00000394156.7
CDH11
Intron
SCLC-A


chr16: 64997126
ENST00000394156.7
CDH11
Intron
SCLC-A


chr16: 68590727
ENST00000612545.1
NA
Promoter
SCLC-A


chr16: 68590747
ENST00000612545.1
NA
Promoter
SCLC-A


chr16: 71627044
ENST00000565261.1
MARVELD3
Intron
SCLC-A


chr16: 71627062
ENST00000565261.1
MARVELD3
Intron
SCLC-A


chr16: 71627087
ENST00000565261.1
MARVELD3
Intron
SCLC-A


chr16: 71627110
ENST00000565261.1
MARVELD3
Intron
SCLC-A


chr16: 71627142
ENST00000565261.1
MARVELD3
Intron
SCLC-A


chr16: 71627229
ENST00000565261.1
MARVELD3
Intron
SCLC-A


chr16: 71627231
ENST00000565261.1
MARVELD3
Intron
SCLC-A


chr16: 71627269
ENST00000565261.1
MARVELD3
Intron
SCLC-A


chr16: 71627274
ENST00000565261.1
MARVELD3
Intron
SCLC-A


chr16: 71627278
ENST00000565261.1
MARVELD3
Intron
SCLC-A


chr16: 71627429
ENST00000565261.1
MARVELD3
Intron
SCLC-A


chr16: 77789719
ENST00000302536.3
VAT1L
Intron
SCLC-A


chr16: 77789811
ENST00000302536.3
VAT1L
Intron
SCLC-A


chr16: 77789828
ENST00000302536.3
VAT1L
Intron
SCLC-A


chr16: 78580325
ENST00000402655.6
WWOX
Intron
SCLC-A


chr16: 78580326
ENST00000402655.6
WWOX
Intron
SCLC-A


chr16: 78597146
ENST00000402655.6
WWOx
Intron
SCLC-A


chr16: 78993665
ENST00000402655.6
WWOX
Intron
SCLC-A


chr16: 78993668
ENST00000402655.6
WWOX
Intron
SCLC-A


chr16: 78993669
ENST00000402655.6
WWOX
Intron
SCLC-A


chr16: 78993688
ENST00000402655.6
WWOx
Intron
SCLC-A


chr16: 78993753
ENST00000402655.6
WWOX
Intron
SCLC-A


chr16: 78993754
ENST00000402655.6
WWOX
Intron
SCLC-A


chr16: 78993777
ENST00000402655.6
WWOX
Intron
SCLC-A


chr16: 85171183
ENST00000637419.1
GSE1
Exon
SCLC-A


chr16: 85171201
ENST00000637419.1
GSE1
Exon
SCLC-A


chr16: 85171330
ENST00000637419.1
GSE1
Exon
SCLC-A


chr16: 85214654
ENST00000637419.1
GSE1
Intron
SCLC-A


chr16: 85247654
ENST00000637419.1
GSE1
Intron
SCLC-A


chr16: 85287017
ENST00000637419.1
GSE1
Intron
SCLC-A


chr16: 85287049
ENST00000637419.1
GSE1
Intron
SCLC-A


chr16: 85287080
ENST00000637419.1
GSE1
Intron
SCLC-A


chr16: 85287095
ENST00000637419.1
GSE1
Intron
SCLC-A


chr16: 85287116
ENST00000637419.1
GSE1
Intron
SCLC-A


chr16: 85287162
ENST00000637419.1
GSE1
Intron
SCLC-A


chr16: 85354629
ENST00000637419.1
GSE1
Intron
SCLC-A


chr16: 85379139
ENST00000637419.1
GSE1
Intron
SCLC-A


chr16: 85381912
ENST00000637419.1
GSE1
Intron
SCLC-A


chr16: 85382047
ENST00000637419.1
GSE1
Intron
SCLC-A


chr16: 88886879
ENST00000565053.1
LOC101927793
Exon
SCLC-A


chr16: 88886886
ENST00000565053.1
LOC101927793
Exon
SCLC-A


chr16: 88886908
ENST00000565053.1
LOC101927793
Exon
SCLC-A


chr16: 88886922
ENST00000565053.1
LOC101927793
Exon
SCLC-A


chr16: 88886924
ENST00000565053.1
LOC101927793
Exon
SCLC-A


chr16: 88886931
ENST00000565053.1
LOC101927793
Exon
SCLC-A


chr16: 88886934
ENST00000565053.1
LOC101927793
Exon
SCLC-A


chr16: 88886939
ENST00000565053.1
LOC101927793
Exon
SCLC-A


chr16: 88886970
ENST00000565053.1
LOC101927793
Exon
SCLC-A


chr16: 88886977
ENST00000565053.1
LOC101927793
Exon
SCLC-A


chr16: 88887475
ENST00000327483.9
CBFA2T3
Intron
SCLC-A


chr16: 88887480
ENST00000327483.9
CBFA2T3
Intron
SCLC-A


chr16: 88887588
ENST00000327483.9
CBFA2T3
Intron
SCLC-A


chr16: 88887597
ENST00000327483.9
CBFA2T3
Intron
SCLC-A


chr16: 88922613
ENST00000268679.9
CBFA2T3
Intron
SCLC-A


chr16: 88936828
ENST00000268679.9
CBFA2T3
Intron
SCLC-A


chr17: 1998369
ENST00000331238.7
RTN4RL1
Intron
SCLC-A


chr17: 1998382
ENST00000331238.7
RTN4RL1
Intron
SCLC-A


chr17: 1998395
ENST00000331238.7
RTN4RL1
Intron
SCLC-A


chr17: 1998403
ENST00000331238.7
RTN4RL1
Intron
SCLC-A


chr17: 1998405
ENST00000331238.7
RTN4RL1
Intron
SCLC-A


chr17: 1998409
ENST00000331238.7
RTN4RL1
Intron
SCLC-A


chr17: 1998411
ENST00000331238.7
RTN4RL1
Intron
SCLC-A


chr17: 1998431
ENST00000331238.7
RTN4RL1
Intron
SCLC-A


chr17: 2174707
ENST00000263073.11
SMG6
Intron
SCLC-A


chr17: 2174708
ENST00000263073.11
SMG6
Intron
SCLC-A


chr17: 3911669
ENST00000572418.1
P2RX1
Intron
SCLC-A


chr17: 3911674
ENST00000572418.1
P2RX1
Intron
SCLC-A


chr17: 3911701
ENST00000572418.1
P2RX1
Intron
SCLC-A


chr17: 3911707
ENST00000572418.1
P2RX1
Intron
SCLC-A


chr17: 7384105
ENST00000577009.1
TNK1
Promoter
SCLC-A


chr17: 7384131
ENST00000577009.1
TNK1
Promoter
SCLC-A


chr17: 7384149
ENST00000577009.1
TNK1
Promoter
SCLC-A


chr17: 7384152
ENST00000577009.1
TNK1
Promoter
SCLC-A


chr17: 7384179
ENST00000577009.1
TNK1
Promoter
SCLC-A


chr17: 7384180
ENST00000577009.1
TNK1
Promoter
SCLC-A


chr17: 7384190
ENST00000577009.1
TNK1
Promoter
SCLC-A


chr17: 9212784
ENST00000173229.7
NTN1
Intron
SCLC-A


chr17: 9212826
ENST00000173229.7
NTN1
Intron
SCLC-A


chr17: 9212846
ENST00000173229.7
NTN1
Intron
SCLC-A


chr17: 9212875
ENST00000173229.7
NTN1
Intron
SCLC-A


chr17: 9828889
ENST00000574745.5
GLP2R
Intron
SCLC-A


chr17: 9847489
ENST00000574745.5
GLP2R
Intron
SCLC-A


chr17: 10570616
ENST00000587182.2
MYHAS
Intron
SCLC-A


chr17: 10570716
ENST00000587182.2
MYHAS
Intron
SCLC-A


chr17: 10621565
ENST00000587182.2
MYHAS
Intron
SCLC-A


chr17: 11202000
ENST00000648331.1
NA
Intron
SCLC-A


chr17: 19003757
ENST00000417251.6
SLC5A10
Intron
SCLC-A


chr17: 19003791
ENST00000417251.6
SLC5A10
Intron
SCLC-A


chr17: 19003814
ENST00000417251.6
SLC5A10
Intron
SCLC-A


chr17: 19003819
ENST00000417251.6
SLC5A10
Intron
SCLC-A


chr17: 19003820
ENST00000417251.6
SLC5A10
Intron
SCLC-A


chr17: 19003828
ENST00000417251.6
SLC5A10
Intron
SCLC-A


chr17: 19003829
ENST00000417251.6
SLC5A10
Intron
SCLC-A


chr17: 19003845
ENST00000417251.6
SLC5A10
Intron
SCLC-A


chr17: 19003846
ENST00000417251.6
SLC5A10
Intron
SCLC-A


chr17: 19003862
ENST00000417251.6
SLC5A10
Intron
SCLC-A


chr17: 19003875
ENST00000417251.6
SLC5A10
Intron
SCLC-A


chr17: 19003887
ENST00000417251.6
SLC5A10
Intron
SCLC-A


chr17: 19003888
ENST00000417251.6
SLC5A10
Intron
SCLC-A


chr17: 19003909
ENST00000417251.6
SLC5A10
Intron
SCLC-A


chr17: 20256098
ENST00000580225.1
NA
Intron
SCLC-A


chr17: 20256112
ENST00000580225.1
NA
Intron
SCLC-A


chr17: 21453265
ENST00000654263.1
NA
Intron
SCLC-A


chr17: 21453285
ENST00000654263.1
NA
Intron
SCLC-A


chr17: 31409827
ENST00000621161.5
RAB11FIP4
Intron
SCLC-A


chr17: 37507513
ENST00000617516.5
DUSP14
Intron
SCLC-A


chr17: 37512705
ENST00000614411.1
DUSP14
Exon
SCLC-A


chr17: 37512706
ENST00000614411.1
DUSP14
Exon
SCLC-A


chr17: 37512726
ENST00000614411.1
DUSP14
Exon
SCLC-A


chr17: 37512885
ENST00000614411.1
DUSP14
Exon
SCLC-A


chr17: 37512896
ENST00000614411.1
DUSP14
Exon
SCLC-A


chr17: 37512897
ENST00000614411.1
DUSP14
Exon
SCLC-A


chr17: 39700220
ENST00000578199.5
ERBB2
Intron
SCLC-A


chr17: 39700343
ENST00000578199.5
ERBB2
Intron
SCLC-A


chr17: 39700370
ENST00000578199.5
ERBB2
Intron
SCLC-A


chr17: 39700381
ENST00000578199.5
ERBB2
Intron
SCLC-A


chr17: 39700383
ENST00000578199.5
ERBB2
Intron
SCLC-A


chr17: 39700475
ENST00000578199.5
ERBB2
Intron
SCLC-A


chr17: 39700479
ENST00000578199.5
ERBB2
Intron
SCLC-A


chr17: 39700503
ENST00000578199.5
ERBB2
Intron
SCLC-A


chr17: 39700508
ENST00000578199.5
ERBB2
Intron
SCLC-A


chr17: 45688870
ENST00000634540.1
LINC02210-CRHR1
Intron
SCLC-A


chr17: 45688887
ENST00000634540.1
LINC02210-CRHR1
Intron
SCLC-A


chr17: 48543085
ENST00000504972.3
HOXB-AS1
Promoter
SCLC-A


chr17: 48543181
ENST00000504972.3
HOXB-AS1
Promoter
SCLC-A


chr17: 48543202
ENST00000504972.3
HOXB-AS1
Promoter
SCLC-A


chr17: 48544564
ENST00000504972.3
HOXB-AS1
Intron
SCLC-A


chr17: 48550531
ENST00000470495.1
HOXB3
Exon
SCLC-A


chr17: 48550541
ENST00000470495.1
HOXB3
Exon
SCLC-A


chr17: 48550542
ENST00000470495.1
HOXB3
Exon
SCLC-A


chr17: 48550547
ENST00000470495.1
HOXB3
Exon
SCLC-A


chr17: 48550548
ENST00000470495.1
HOXB3
Exon
SCLC-A


chr17: 48550553
ENST00000470495.1
HOXB3
Exon
SCLC-A


chr17: 48550554
ENST00000470495.1
HOXB3
Exon
SCLC-A


chr17: 48550555
ENST00000470495.1
HOXB3
Exon
SCLC-A


chr17: 48550556
ENST00000470495.1
HOXB3
Exon
SCLC-A


chr17: 48550561
ENST00000470495.1
HOXB3
Exon
SCLC-A


chr17: 48550568
ENST00000470495.1
HOXB3
Exon
SCLC-A


chr17: 48550573
ENST00000470495.1
HOXB3
Exon
SCLC-A


chr17: 48550581
ENST00000470495.1
HOXB3
Exon
SCLC-A


chr17: 48550638
ENST00000470495.1
HOXB3
Exon
SCLC-A


chr17: 48550914
ENST00000470495.1
HOXB3
Exon
SCLC-A


chr17: 48550941
ENST00000470495.1
HOXB3
Exon
SCLC-A


chr17: 48550945
ENST00000470495.1
HOXB3
Exon
SCLC-A


chr17: 48551664
ENST00000465846.6
HOXB-AS3
Intron
SCLC-A


chr17: 48578115
ENST00000465846.6
HOXB-AS3
Intron
SCLC-A


chr17: 48578123
ENST00000465846.6
HOXB-AS3
Intron
SCLC-A


chr17: 48578125
ENST00000465846.6
HOXB-AS3
Intron
SCLC-A


chr17: 48578130
ENST00000465846.6
HOXB-AS3
Intron
SCLC-A


chr17: 48578137
ENST00000465846.6
HOXB-AS3
Intron
SCLC-A


chr17: 48578165
ENST00000465846.6
HOXB-AS3
Intron
SCLC-A


chr17: 48578171
ENST00000465846.6
HOXB-AS3
Intron
SCLC-A


chr17: 50170246
ENST00000513942.5
SGCA
Intron
SCLC-A


chr17: 50194705
ENST00000476387.1
COL1A1
Promoter
SCLC-A


chr17: 50194723
ENST00000476387.1
COL1A1
Promoter
SCLC-A


chr17: 50194727
ENST00000476387.1
COL1A1
Promoter
SCLC-A


chr17: 50194739
ENST00000476387.1
COL1A1
Promoter
SCLC-A


chr17: 50469399
ENST00000510410.5
ACSF2
Intron
SCLC-A


chr17: 57291116
ENST00000416426.6
MSI2
Intron
SCLC-A


chr17: 57291119
ENST00000416426.6
MSI2
Intron
SCLC-A


chr17: 57291159
ENST00000416426.6
MSI2
Intron
SCLC-A


chr17: 57313711
ENST00000416426.6
MSI2
Intron
SCLC-A


chr17: 57313728
ENST00000416426.6
MSI2
Intron
SCLC-A


chr17: 57313744
ENST00000416426.6
MSI2
Intron
SCLC-A


chr17: 57863162
ENST00000577830.6
CUEDC1
Exon
SCLC-A


chr17: 57863169
ENST00000577830.6
CUEDC1
Exon
SCLC-A


chr17: 72116684
ENST00000529667.1
SOX9-AS1
Intron
SCLC-A


chr17: 72122814
ENST00000628742.2
SOX9-AS1
Intron
SCLC-A


chr17: 72122816
ENST00000628742.2
SOX9-AS1
Intron
SCLC-A


chr17: 72122866
ENST00000628742.2
SOX9-AS1
Intron
SCLC-A


chr17: 72122904
ENST00000628742.2
SOX9-AS1
Intron
SCLC-A


chr17: 72122914
ENST00000628742.2
SOX9-AS1
Intron
SCLC-A


chr17: 72123011
ENST00000628742.2
SOX9-AS1
Intron
SCLC-A


chr17: 72123016
ENST00000628742.2
SOX9-AS1
Intron
SCLC-A


chr17: 72123038
ENST00000628742.2
SOX9-AS1
Intron
SCLC-A


chr17: 74342167
ENST00000551294.5
KIF19
Intron
SCLC-A


chr17: 74749702
ENST00000585285.1
NA
Promoter
SCLC-A


chr17: 74749722
ENST00000585285.1
NA
Promoter
SCLC-A


chr17: 74749723
ENST00000585285.1
NA
Promoter
SCLC-A


chr17: 74749726
ENST00000585285.1
NA
Promoter
SCLC-A


chr17: 74749727
ENST00000585285.1
NA
Promoter
SCLC-A


chr17: 74749783
ENST00000585285.1
NA
Promoter
SCLC-A


chr17: 76500832
ENST00000585989.5
RHBDF2
Intron
SCLC-A


chr17: 76500871
ENST00000585989.5
RHBDF2
Intron
SCLC-A


chr17: 76500989
ENST00000585989.5
RHBDF2
Intron
SCLC-A


chr17: 76500995
ENST00000585989.5
RHBDF2
Intron
SCLC-A


chr17: 76501008
ENST00000585989.5
RHBDF2
Intron
SCLC-A


chr17: 76707050
ENST00000355797.7
MXRA7
Intron
SCLC-A


chr17: 76707068
ENST00000355797.7
MXRA7
Intron
SCLC-A


chr17: 77147112
ENST00000589827.5
SEC14L1
Intron
SCLC-A


chr17: 77147117
ENST00000589827.5
SEC14L1
Intron
SCLC-A


chr17: 77147125
ENST00000589827.5
SEC14L1
Intron
SCLC-A


chr17: 77147254
ENST00000589827.5
SEC14L1
Intron
SCLC-A


chr17: 77209273
ENST00000392476.6
SEC14L1
Intron
SCLC-A


chr17: 77209289
ENST00000392476.6
SEC14L1
Intron
SCLC-A


chr17: 77376297
ENST00000589070.1
SEPTIN9
Intron
SCLC-A


chr17: 77376327
ENST00000589070.1
SEPTIN9
Intron
SCLC-A


chr17: 77376328
ENST00000589070.1
SEPTIN9
Intron
SCLC-A


chr17: 77376339
ENST00000589070.1
SEPTIN9
Intron
SCLC-A


chr17: 77376342
ENST00000589070.1
SEPTIN9
Intron
SCLC-A


chr17: 77376365
ENST00000589070.1
SEPTIN9
Intron
SCLC-A


chr17: 79465822
ENST00000583458.5
RBFOX3
Intron
SCLC-A


chr17: 81171171
ENST00000414089.5
PVALEF
Intron
SCLC-A


chr17: 81171258
ENST00000414089.5
PVALEF
Intron
SCLC-A


chr18: 499383
ENST00000400256.5
COLEC12
Intron
SCLC-A


chr18: 5890339
ENST00000581347.2
TMEM200C
Exon
SCLC-A


chr18: 5890342
ENST00000581347.2
TMEM200C
Exon
SCLC-A


chr18: 5890354
ENST00000581347.2
TMEM200C
Exon
SCLC-A


chr18: 5890365
ENST00000581347.2
TMEM200C
Exon
SCLC-A


chr18: 5890371
ENST00000581347.2
TMEM200C
Exon
SCLC-A


chr18: 74900924
ENST00000577538.5
ZNF407
Intron
SCLC-A


chr18: 74900968
ENST00000577538.5
ZNF407
Intron
SCLC-A


chr18: 74902241
ENST00000577538.5
ZNF407
Intron
SCLC-A


chr18: 74902300
ENST00000577538.5
ZNF407
Intron
SCLC-A


chr18: 74902301
ENST00000577538.5
ZNF407
Intron
SCLC-A


chr18: 74902320
ENST00000577538.5
ZNF407
Intron
SCLC-A


chr18: 74902321
ENST00000577538.5
ZNF407
Intron
SCLC-A


chr18: 74902335
ENST00000577538.5
ZNF407
Intron
SCLC-A


chr18: 74902336
ENST00000577538.5
ZNF407
Intron
SCLC-A


chr18: 74902342
ENST00000577538.5
ZNF407
Intron
SCLC-A


chr18: 74902343
ENST00000577538.5
ZNF407
Intron
SCLC-A


chr18: 74902365
ENST00000577538.5
ZNF407
Intron
SCLC-A


chr18: 75455550
ENST00000657893.1
NA
Promoter
SCLC-A


chr18: 75455569
ENST00000657893.1
NA
Promoter
SCLC-A


chr18: 75455571
ENST00000657893.1
NA
Promoter
SCLC-A


chr18: 80040002
ENST00000569722.5
RBFA
Intron
SCLC-A


chr19: 427239
ENST00000590170.3
SHC2
Intron
SCLC-A


chr19: 427240
ENST00000590170.3
SHC2
Intron
SCLC-A


chr19: 427245
ENST00000590170.3
SHC2
Intron
SCLC-A


chr19: 427258
ENST00000590170.3
SHC2
Intron
SCLC-A


chr19: 1470256
ENST00000588427.5
C19orf25
Intron
SCLC-A


chr19: 1470259
ENST00000588427.5
C19orf25
Intron
SCLC-A


chr19: 1470285
ENST00000588427.5
C19orf25
Intron
SCLC-A


chr19: 6074027
ENST00000589742.5
RFX2
Intron
SCLC-A


chr19: 6074028
ENST00000589742.5
RFX2
Intron
SCLC-A


chr19: 6074113
ENST00000589742.5
RFX2
Intron
SCLC-A


chr19: 6074154
ENST00000589742.5
RFX2
Intron
SCLC-A


chr19: 6074157
ENST00000589742.5
RFX2
Intron
SCLC-A


chr19: 6074182
ENST00000589742.5
RFX2
Intron
SCLC-A


chr19: 6074209
ENST00000589742.5
RFX2
Intron
SCLC-A


chr19: 6074210
ENST00000589742.5
RFX2
Intron
SCLC-A


chr19: 12754697
ENST00000549706.5
BEST2
Exon
SCLC-A


chr19: 12754708
ENST00000549706.5
BEST2
Exon
SCLC-A


chr19: 12754725
ENST00000549706.5
BEST2
Exon
SCLC-A


chr19: 13593983
ENST00000574974.3
CACNA1A
Intron
SCLC-A


chr19: 13593987
ENST00000574974.3
CACNA1A
Intron
SCLC-A


chr19: 14434607
ENST00000585619.5
PKN1
Intron
SCLC-A


chr19: 18461133
ENST00000262809.9
ELL
Intron
SCLC-A


chr19: 18461149
ENST00000262809.9
ELL
Intron
SCLC-A


chr19: 18743798
ENST00000321949.13
CRTC1
Intron
SCLC-A


chr19: 18745079
ENST00000321949.13
CRTC1
Intron
SCLC-A


chr19: 33393324
ENST00000244137.12
PEPD
Intron
SCLC-A


chr19: 33393408
ENST00000244137.12
PEPD
Intron
SCLC-A


chr19: 33393478
ENST00000244137.12
PEPD
Intron
SCLC-A


chr19: 35494521
ENST00000479340.1
KRTDAP
Intron
SCLC-A


chr19: 36111394
ENST00000585332.3
OVOL3
Exon
SCLC-A


chr19: 36111668
ENST00000633214.1
OVOL3
Intron
SCLC-A


chr19: 38253025
ENST00000590510.5
SPINT2
Intron
SCLC-A


chr19: 38253057
ENST00000590510.5
SPINT2
Intron
SCLC-A


chr19: 40275139
ENST00000391844.8
AKT2
Intron
SCLC-A


chr19: 46001416
ENST00000536603.5
CCDC61
Intron
SCLC-A


chr19: 46493529
ENST00000602017.5
PPP5D1
Intron
SCLC-A


chr19: 46493540
ENST00000602017.5
PPP5D1
Intron
SCLC-A


chr19: 46493562
ENST00000602017.5
PPP5D1
Intron
SCLC-A


chr19: 46493583
ENST00000602017.5
PPP5D1
Intron
SCLC-A


chr19: 46493592
ENST00000602017.5
PPP5D1
Intron
SCLC-A


chr19: 46493606
ENST00000602017.5
PPP5D1
Intron
SCLC-A


chr19: 46493631
ENST00000602017.5
PPP5D1
Intron
SCLC-A


chr19: 48728959
ENST00000599291.1
RASIP1
Intron
SCLC-A


chr19: 48729058
ENST00000599291.1
RASIP1
Intron
SCLC-A


chr19: 48729120
ENST00000599291.1
RASIP1
Intron
SCLC-A


chr19: 48729133
ENST00000599291.1
RASIP1
Intron
SCLC-A


chr19: 48729248
ENST00000599291.1
RASIP1
Intron
SCLC-A


chr19: 48729249
ENST00000599291.1
RASIP1
Intron
SCLC-A


chr19: 49104754
ENST00000601065.5
SNRNP70
Intron
SCLC-A


chr19: 50240302
ENST00000598205.5
MYH14
Intron
SCLC-A


chr19: 50276060
ENST00000440075.6
MYH14
UTR5
SCLC-A


chr19: 50543108
ENST00000599957.5
LRRC4B
Intron
SCLC-A


chr19: 55359800
ENST00000585734.5
FAM71E2
Exon
SCLC-A


chr19: 56217428
ENST00000474329.2
NA
Exon
SCLC-A


chr19: 56217452
ENST00000474329.2
NA
Exon
SCLC-A


chr19: 56217478
ENST00000474329.2
NA
Exon
SCLC-A


chr19: 56217554
ENST00000474329.2
NA
Exon
SCLC-A


chr19: 56217563
ENST00000474329.2
NA
Exon
SCLC-A


chr19: 56217567
ENST00000474329.2
NA
Exon
SCLC-A


chr19: 56217571
ENST00000474329.2
NA
Exon
SCLC-A


chr19: 56217718
ENST00000474329.2
NA
Exon
SCLC-A


chr19: 56217723
ENST00000474329.2
NA
Exon
SCLC-A


chr19: 56217743
ENST00000474329.2
NA
Exon
SCLC-A


chr19: 56217762
ENST00000474329.2
NA
Exon
SCLC-A


chr19: 56217775
ENST00000474329.2
NA
Exon
SCLC-A


chr19: 56217798
ENST00000474329.2
NA
Promoter
SCLC-A


chr19: 56217840
ENST00000474329.2
NA
Promoter
SCLC-A


chr19: 56217842
ENST00000474329.2
NA
Promoter
SCLC-A


chr19: 56217844
ENST00000474329.2
NA
Promoter
SCLC-A


chr19: 56217846
ENST00000474329.2
NA
Promoter
SCLC-A


chr2: 1680504
ENST00000252804.9
PXDN
Intron
SCLC-A


chr2: 6958060
ENST00000467276.5
RNF144A
Intron
SCLC-A


chr2: 7020509
ENST00000467276.5
RNF144A
Exon
SCLC-A


chr2: 8503048
ENST00000670008.1
LINC01814
Intron
SCLC-A


chr2: 8503070
ENST00000670008.1
LINC01814
Intron
SCLC-A


chr2: 8528861
ENST00000670008.1
LINC01814
Intron
SCLC-A


chr2: 8545546
ENST00000670008.1
LINC01814
Intron
SCLC-A


chr2: 8676641
ENST00000455965.6
ID2-AS1
Intron
SCLC-A


chr2: 8676643
ENST00000455965.6
ID2-AS1
Intron
SCLC-A


chr2: 8676714
ENST00000455965.6
ID2-AS1
Intron
SCLC-A


chr2: 8676725
ENST00000455965.6
ID2-AS1
Intron
SCLC-A


chr2: 8676733
ENST00000455965.6
ID2-AS1
Intron
SCLC-A


chr2: 8676787
ENST00000455965.6
ID2-AS1
Intron
SCLC-A


chr2: 8676789
ENST00000455965.6
ID2-AS1
Intron
SCLC-A


chr2: 8676793
ENST00000455965.6
ID2-AS1
Intron
SCLC-A


chr2: 8676854
ENST00000455965.6
ID2-AS1
Intron
SCLC-A


chr2: 9379004
ENST00000315273.4
ASAP2
Exon
SCLC-A


chr2: 9379035
ENST00000315273.4
ASAP2
Exon
SCLC-A


chr2: 10911362
ENST00000295082.3
KCNF1
Promoter
SCLC-A


chr2: 11677228
ENST00000449576.6
LPIN1
Promoter
SCLC-A


chr2: 11677265
ENST00000449576.6
LPIN1
Promoter
SCLC-A


chr2: 11677266
ENST00000449576.6
LPIN1
Promoter
SCLC-A


chr2: 11677662
ENST00000617634.1
NA
Promoter
SCLC-A


chr2: 11677663
ENST00000617634.1
NA
Promoter
SCLC-A


chr2: 11677669
ENST00000617634.1
NA
Promoter
SCLC-A


chr2: 11697772
ENST00000449576.6
LPIN1
Intron
SCLC-A


chr2: 19125197
ENST00000449124.1
NA
Intron
SCLC-A


chr2: 23563598
ENST00000486442.6
KLHL29
Intron
SCLC-A


chr2: 23563632
ENST00000486442.6
KLHL29
Intron
SCLC-A


chr2: 23563634
ENST00000486442.6
KLHL29
Intron
SCLC-A


chr2: 23656640
ENST00000486442.6
KLHL29
Intron
SCLC-A


chr2: 23656658
ENST00000486442.6
KLHL29
Intron
SCLC-A


chr2: 23656731
ENST00000486442.6
KLHL29
Intron
SCLC-A


chr2: 23656732
ENST00000486442.6
KLHL29
Intron
SCLC-A


chr2: 23656760
ENST00000486442.6
KLHL29
Intron
SCLC-A


chr2: 23656805
ENST00000486442.6
KLHL29
Intron
SCLC-A


chr2: 24010805
ENST00000406420.7
MFSD2B
Intron
SCLC-A


chr2: 24010822
ENST00000406420.7
MFSD2B
Intron
SCLC-A


chr2: 24010887
ENST00000406420.7
MFSD2B
Intron
SCLC-A


chr2: 24010950
ENST00000406420.7
MFSD2B
Intron
SCLC-A


chr2: 24886737
ENST00000435135.5
ADCY3
Intron
SCLC-A


chr2: 24886746
ENST00000435135.5
ADCY3
Intron
SCLC-A


chr2: 24886769
ENST00000435135.5
ADCY3
Intron
SCLC-A


chr2: 24886961
ENST00000435135.5
ADCY3
Intron
SCLC-A


chr2: 25419501
ENST00000496972.6
DTNB
Intron
SCLC-A


chr2: 25419709
ENST00000496972.6
DTNB
Intron
SCLC-A


chr2: 34051135
ENST00000366209.6
LINC01317
Intron
SCLC-A


chr2: 34289711
ENST00000650021.1
LINC01320
Intron
SCLC-A


chr2: 43224560
ENST00000282388.4
ZFP36L2
Exon
SCLC-A


chr2: 43224562
ENST00000282388.4
ZFP36L2
Exon
SCLC-A


chr2: 43224575
ENST00000282388.4
ZFP36L2
Exon
SCLC-A


chr2: 43224881
ENST00000282388.4
ZFP36L2
Exon
SCLC-A


chr2: 43225335
ENST00000282388.4
ZFP36L2
Exon
SCLC-A


chr2: 43225336
ENST00000282388.4
ZFP36L2
Exon
SCLC-A


chr2: 43225349
ENST00000282388.4
ZFP36L2
Exon
SCLC-A


chr2: 43225369
ENST00000282388.4
ZFP36L2
Exon
SCLC-A


chr2: 46983312
ENST00000409245.5
TTC7A
Intron
SCLC-A


chr2: 46983348
ENST00000409245.5
TTC7A
Intron
SCLC-A


chr2: 46983349
ENST00000409245.5
TTC7A
Intron
SCLC-A


chr2: 46983376
ENST00000409245.5
TTC7A
Intron
SCLC-A


chr2: 46983377
ENST00000409245.5
TTC7A
Intron
SCLC-A


chr2: 46983413
ENST00000409245.5
TTC7A
Intron
SCLC-A


chr2: 46983446
ENST00000409245.5
TTC7A
Intron
SCLC-A


chr2: 46983461
ENST00000409245.5
TTC7A
Intron
SCLC-A


chr2: 47370310
ENST00000405271.5
EPCAM
Intron
SCLC-A


chr2: 47370334
ENST00000405271.5
EPCAM
Intron
SCLC-A


chr2: 47370340
ENST00000405271.5
EPCAM
Intron
SCLC-A


chr2: 63051505
ENST00000477348.1
OTX1
Exon
SCLC-A


chr2: 67561566
ENST00000433065.1
NA
Promoter
SCLC-A


chr2: 67561575
ENST00000433065.1
NA
Promoter
SCLC-A


chr2: 67561705
ENST00000433065.1
NA
Promoter
SCLC-A


chr2: 96143896
ENST00000288943.5
DUSP2
Exon
SCLC-A


chr2: 96143899
ENST00000288943.5
DUSP2
Exon
SCLC-A


chr2: 96143909
ENST00000288943.5
DUSP2
Exon
SCLC-A


chr2: 96143924
ENST00000288943.5
DUSP2
Exon
SCLC-A


chr2: 96143932
ENST00000288943.5
DUSP2
Exon
SCLC-A


chr2: 96143938
ENST00000288943.5
DUSP2
Exon
SCLC-A


chr2: 96143941
ENST00000288943.5
DUSP2
Exon
SCLC-A


chr2: 96143981
ENST00000288943.5
DUSP2
Exon
SCLC-A


chr2: 96143983
ENST00000288943.5
DUSP2
Exon
SCLC-A


chr2: 96143992
ENST00000288943.5
DUSP2
Exon
SCLC-A


chr2: 96144014
ENST00000288943.5
DUSP2
Exon
SCLC-A


chr2: 98357101
ENST00000393504.5
CNGA3
Intron
SCLC-A


chr2: 109482629
ENST00000309415.8
SH3RF3
Intron
SCLC-A


chr2: 109482630
ENST00000309415.8
SH3RF3
Intron
SCLC-A


chr2: 109498112
ENST00000309415.8
SH3RF3
Intron
SCLC-A


chr2: 109498141
ENST00000309415.8
SH3RF3
Intron
SCLC-A


chr2: 109498160
ENST00000309415.8
SH3RF3
Intron
SCLC-A


chr2: 109498161
ENST00000309415.8
SH3RF3
Intron
SCLC-A


chr2: 109498193
ENST00000309415.8
SH3RF3
Intron
SCLC-A


chr2: 109498196
ENST00000309415.8
SH3RF3
Intron
SCLC-A


chr2: 127071160
ENST00000376113.6
BIN1
Intron
SCLC-A


chr2: 131528743
ENST00000434330.1
CCDC74A
Promoter
SCLC-A


chr2: 131528787
ENST00000434330.1
CCDC74A
Promoter
SCLC-A


chr2: 131528898
ENST00000434330.1
CCDC74A
Promoter
SCLC-A


chr2: 144404070
ENST00000638087.1
ZEB2
Exon
SCLC-A


chr2: 166610661
ENST00000650747.1
SCN7A
Intron
SCLC-A


chr2: 166610663
ENST00000650747.1
SCN7A
Intron
SCLC-A


chr2: 166610666
ENST00000650747.1
SCN7A
Intron
SCLC-A


chr2: 166610700
ENST00000650747.1
SCN7A
Intron
SCLC-A


chr2: 181656516
ENST00000479558.5
CERKL
Intron
SCLC-A


chr2: 181656577
ENST00000479558.5
CERKL
Intron
SCLC-A


chr2: 237508969
ENST00000422695.5
MLPH
Intron
SCLC-A


chr20: 11247539
ENST00000444792.1
LOC339593
Intron
SCLC-A


chr20: 11271495
ENST00000666460.1
LOC339593
Intron
SCLC-A


chr20: 11271529
ENST00000666460.1
LOC339593
Intron
SCLC-A


chr20: 19759038
ENST00000432334.2
RIN2
Intron
SCLC-A


chr20: 20562289
ENST00000202677.12
RALGAPA2
Intron
SCLC-A


chr20: 20562488
ENST00000202677.12
RALGAPA2
Intron
SCLC-A


chr20: 20562510
ENST00000202677.12
RALGAPA2
Intron
SCLC-A


chr20: 21101464
ENST00000655093.1
LINC00237
Intron
SCLC-A


chr20: 21101552
ENST00000655093.1
LINC00237
Intron
SCLC-A


chr20: 21101558
ENST00000655093.1
LINC00237
Intron
SCLC-A


chr20: 21101575
ENST00000655093.1
LINC00237
Intron
SCLC-A


chr20: 23084938
ENST00000246006.5
CD93
Exon
SCLC-A


chr20: 23084947
ENST00000246006.5
CD93
Exon
SCLC-A


chr20: 23084948
ENST00000246006.5
CD93
Exon
SCLC-A


chr20: 23085004
ENST00000246006.5
CD93
Exon
SCLC-A


chr20: 23085011
ENST00000246006.5
CD93
Exon
SCLC-A


chr20: 23085015
ENST00000246006.5
CD93
Exon
SCLC-A


chr20: 23085064
ENST00000246006.5
CD93
Exon
SCLC-A


chr20: 23085069
ENST00000246006.5
CD93
Exon
SCLC-A


chr20: 32574566
ENST00000621426.6
NOL4L
Intron
SCLC-A


chr20: 32581433
ENST00000621426.6
NOL4L
Intron
SCLC-A


chr20: 32676689
ENST00000646357.1
C20orf203
Intron
SCLC-A


chr20: 32676733
ENST00000646357.1
C20orf203
Intron
SCLC-A


chr20: 36471322
ENST00000373913.7
DLGAP4
Intron
SCLC-A


chr20: 36471323
ENST00000373913.7
DLGAP4
Intron
SCLC-A


chr20: 36471351
ENST00000373913.7
DLGAP4
Intron
SCLC-A


chr20: 36529602
ENST00000439595.5
DLGAP4-AS1
Intron
SCLC-A


chr20: 36852377
ENST00000237536.9
SOGA1
Intron
SCLC-A


chr20: 53595418
ENST00000431687.5
NA
Intron
SCLC-A


chr20: 53595431
ENST00000431687.5
NA
Intron
SCLC-A


chr20: 60310498
ENST00000667664.1
MIR646HG
Intron
SCLC-A


chr20: 61317297
ENST00000614565.5
CDH4
Intron
SCLC-A


chr20: 63065670
ENST00000606208.5
LINC01749
Intron
SCLC-A


chr20: 63065682
ENST00000606208.5
LINC01749
Intron
SCLC-A


chr20: 63069611
ENST00000606208.5
LINC01749
Intron
SCLC-A


chr21: 38661456
ENST00000398910.5
ERG
Intron
SCLC-A


chr21: 38661498
ENST00000398910.5
ERG
Intron
SCLC-A


chr21: 38661510
ENST00000398910.5
ERG
Intron
SCLC-A


chr21: 38661526
ENST00000398910.5
ERG
Intron
SCLC-A


chr21: 38661529
ENST00000398910.5
ERG
Intron
SCLC-A


chr21: 38661621
ENST00000398910.5
ERG
Intron
SCLC-A


chr21: 38661628
ENST00000398910.5
ERG
Intron
SCLC-A


chr21: 38661637
ENST00000398910.5
ERG
Intron
SCLC-A


chr21: 38661638
ENST00000398910.5
ERG
Intron
SCLC-A


chr21: 38661664
ENST00000398919.6
ERG
Promoter
SCLC-A


chr21: 38661689
ENST00000442448.5
ERG
UTR5
SCLC-A


chr21: 38661696
ENST00000442448.5
ERG
UTR5
SCLC-A


chr21: 38661697
ENST00000442448.5
ERG
UTR5
SCLC-A


chr21: 38661701
ENST00000442448.5
ERG
UTR5
SCLC-A


chr21: 38661705
ENST00000442448.5
ERG
UTR5
SCLC-A


chr21: 38661706
ENST00000442448.5
ERG
UTR5
SCLC-A


chr21: 41835462
ENST00000447016.6
PRDM15
Exon
SCLC-A


chr21: 41835464
ENST00000447016.6
PRDM15
Exon
SCLC-A


chr21: 43936339
ENST00000291572.13
AGPAT3
Intron
SCLC-A


chr21: 43936375
ENST00000291572.13
AGPAT3
Intron
SCLC-A


chr21: 43936379
ENST00000291572.13
AGPAT3
Intron
SCLC-A


chr21: 43936441
ENST00000291572.13
AGPAT3
Intron
SCLC-A


chr21: 43936460
ENST00000291572.13
AGPAT3
Intron
SCLC-A


chr21: 44508171
ENST00000323084.9
TSPEAR
Intron
SCLC-A


chr21: 44508179
ENST00000323084.9
TSPEAR
Intron
SCLC-A


chr21: 44508206
ENST00000323084.9
TSPEAR
Intron
SCLC-A


chr21: 44518949
ENST00000323084.9
TSPEAR
Intron
SCLC-A


chr21: 44518997
ENST00000323084.9
TSPEAR
Intron
SCLC-A


chr21: 44521454
ENST00000323084.9
TSPEAR
Intron
SCLC-A


chr21: 44522598
ENST00000465978.1
TSPEAR-AS2
Intron
SCLC-A


chr21: 44525864
ENST00000465978.1
TSPEAR-AS2
Exon
SCLC-A


chr21: 44525881
ENST00000465978.1
TSPEAR-AS2
Exon
SCLC-A


chr21: 44525890
ENST00000465978.1
TSPEAR-AS2
Exon
SCLC-A


chr21: 44525980
ENST00000323084.9
TSPEAR
Intron
SCLC-A


chr21: 44570184
ENST00000323084.9
TSPEAR
Intron
SCLC-A


chr21: 44589901
ENST00000323084.9
TSPEAR
Intron
SCLC-A


chr21: 44589918
ENST00000323084.9
TSPEAR
Intron
SCLC-A


chr21: 44589919
ENST00000323084.9
TSPEAR
Intron
SCLC-A


chr21: 44590033
ENST00000323084.9
TSPEAR
Intron
SCLC-A


chr21: 44590034
ENST00000323084.9
TSPEAR
Intron
SCLC-A


chr21: 44590045
ENST00000323084.9
TSPEAR
Intron
SCLC-A


chr21: 44602659
ENST00000323084.9
TSPEAR
Intron
SCLC-A


chr21: 44639620
ENST00000323084.9
TSPEAR
Intron
SCLC-A


chr21: 44649130
ENST00000323084.9
TSPEAR
Intron
SCLC-A


chr21: 44658852
ENST00000323084.9
TSPEAR
Intron
SCLC-A


chr21: 44698147
ENST00000323084.9
TSPEAR
Intron
SCLC-A


chr21: 44698191
ENST00000323084.9
TSPEAR
Intron
SCLC-A


chr21: 44698714
ENST00000323084.9
TSPEAR
Intron
SCLC-A


chr21: 44698723
ENST00000323084.9
TSPEAR
Intron
SCLC-A


chr21: 44705577
ENST00000323084.9
TSPEAR
Intron
SCLC-A


chr22: 31579558
ENST00000524296.5
SFI1
Intron
SCLC-A


chr22: 31579562
ENST00000524296.5
SFI1
Intron
SCLC-A


chr22: 31579567
ENST00000524296.5
SFI1
Intron
SCLC-A


chr22: 31579595
ENST00000524296.5
SFI1
Intron
SCLC-A


chr22: 31579607
ENST00000524296.5
SFI1
Intron
SCLC-A


chr22: 31579611
ENST00000524296.5
SFI1
Intron
SCLC-A


chr22: 36816302
ENST00000216200.9
PVALB
Intron
SCLC-A


chr22: 36816346
ENST00000216200.9
PVALB
Intron
SCLC-A


chr22: 36816347
ENST00000216200.9
PVALB
Intron
SCLC-A


chr22: 36816387
ENST00000216200.9
PVALB
Intron
SCLC-A


chr22: 36816390
ENST00000216200.9
PVALB
Intron
SCLC-A


chr22: 36816391
ENST00000216200.9
PVALB
Intron
SCLC-A


chr22: 36816410
ENST00000216200.9
PVALB
Intron
SCLC-A


chr22: 36816411
ENST00000216200.9
PVALB
Intron
SCLC-A


chr22: 36861229
ENST00000619915.1
NCF4-AS1
Intron
SCLC-A


chr22: 37485353
ENST00000438891.5
MFNG
Intron
SCLC-A


chr22: 37485696
ENST00000438891.5
MFNG
Intron
SCLC-A


chr22: 37486040
ENST00000416983.7
MFNG
Exon
SCLC-A


chr22: 37486046
ENST00000416983.7
MFNG
Exon
SCLC-A


chr22: 37486082
ENST00000416983.7
MFNG
Exon
SCLC-A


chr22: 42320519
ENST00000515426.1
TCF20
Intron
SCLC-A


chr22: 42320716
ENST00000515426.1
TCF20
Intron
SCLC-A


chr22: 42431587
ENST00000329021.9
NFAM1
Intron
SCLC-A


chr22: 42431594
ENST00000329021.9
NFAM1
Intron
SCLC-A


chr22: 48871054
ENST00000380981.3
LINC01310
Intron
SCLC-A


chr22: 48871068
ENST00000380981.3
LINC01310
Intron
SCLC-A


chr22: 48871084
ENST00000380981.3
LINC01310
Intron
SCLC-A


chr22: 48871088
ENST00000380981.3
LINC01310
Intron
SCLC-A


chr22: 48871168
ENST00000380981.3
LINC01310
Intron
SCLC-A


chr22: 50049855
ENST00000266182.10
TTLL8
Intron
SCLC-A


chr3: 16842354
ENST00000460467.1
PLCL2
Intron
SCLC-A


chr3: 16842392
ENST00000460467.1
PLCL2
Intron
SCLC-A


chr3: 27126857
ENST00000295720.10
NEK10
Intron
SCLC-A


chr3: 27126864
ENST00000295720.10
NEK10
Intron
SCLC-A


chr3: 45594551
ENST00000465039.5
LIMD1
Intron
SCLC-A


chr3: 45594698
ENST00000465039.5
LIMD1
Intron
SCLC-A


chr3: 45594699
ENST00000465039.5
LIMD1
Intron
SCLC-A


chr3: 45796331
ENST00000358525.9
SLC6A20
Exon
SCLC-A


chr3: 45796338
ENST00000358525.9
SLC6A20
Exon
SCLC-A


chr3: 45796353
ENST00000358525.9
SLC6A20
Exon
SCLC-A


chr3: 45796356
ENST00000358525.9
SLC6A20
Exon
SCLC-A


chr3: 45796360
ENST00000358525.9
SLC6A20
Exon
SCLC-A


chr3: 45915943
ENST00000418700.5
LZTFL1
Exon
SCLC-A


chr3: 53167135
ENST00000478843.5
PRKCD
Intron
SCLC-A


chr3: 55702453
ENST00000288221.11
ERC2
Intron
SCLC-A


chr3: 55702593
ENST00000288221.11
ERC2
Intron
SCLC-A


chr3: 120284773
ENST00000464295.5
GPR156
Intron
SCLC-A


chr3: 183179235
ENST00000328913.7
MCF2L2
Exon
SCLC-A


chr3: 183179343
ENST00000328913.7
MCF2L2
Exon
SCLC-A


chr3: 183179354
ENST00000328913.7
MCF2L2
Exon
SCLC-A


chr3: 183179361
ENST00000328913.7
MCF2L2
Exon
SCLC-A


chr3: 183179371
ENST00000328913.7
MCF2L2
Exon
SCLC-A


chr3: 183179395
ENST00000328913.7
MCF2L2
Exon
SCLC-A


chr3: 183179435
ENST00000328913.7
MCF2L2
Exon
SCLC-A


chr3: 183179438
ENST00000328913.7
MCF2L2
Exon
SCLC-A


chr3: 183179812
ENST00000328913.7
MCF2L2
Intron
SCLC-A


chr3: 187743254
ENST00000621333.4
BCL6
Intron
SCLC-A


chr3: 187743320
ENST00000621333.4
BCL6
Intron
SCLC-A


chr3: 187743335
ENST00000621333.4
BCL6
Intron
SCLC-A


chr3: 194305677
ENST00000654752.1
LINC00887
Intron
SCLC-A


chr4: 5807717
ENST00000506216.5
CRMP1
Intron
SCLC-A


chr4: 5807729
ENST00000506216.5
CRMP1
Intron
SCLC-A


chr4: 6957500
ENST00000448507.5
TBC1D14
Intron
SCLC-A


chr4: 6957537
ENST00000448507.5
TBC1D14
Intron
SCLC-A


chr4: 7335853
ENST00000507866.6
SORCS2
Intron
SCLC-A


chr4: 7335859
ENST00000507866.6
SORCS2
Intron
SCLC-A


chr4: 7335860
ENST00000507866.6
SORCS2
Intron
SCLC-A


chr4: 8189669
ENST00000509119.5
SH3TC1
Intron
SCLC-A


chr4: 8189818
ENST00000509119.5
SH3TC1
Intron
SCLC-A


chr4: 8189821
ENST00000509119.5
SH3TC1
Intron
SCLC-A


chr4: 8189832
ENST00000509119.5
SH3TC1
Intron
SCLC-A


chr4: 52750883
ENST00000650700.1
RASL11B
Intron
SCLC-A


chr4: 52750910
ENST00000650700.1
RASL11B
Intron
SCLC-A


chr4: 52750953
ENST00000650700.1
RASL11B
Intron
SCLC-A


chr4: 52750961
ENST00000650700.1
RASL11B
Intron
SCLC-A


chr4: 52750966
ENST00000650700.1
RASL11B
Intron
SCLC-A


chr4: 52750975
ENST00000650700.1
RASL11B
Intron
SCLC-A


chr4: 52751018
ENST00000650700.1
RASL11B
Intron
SCLC-A


chr4: 52751021
ENST00000650700.1
RASL11B
Intron
SCLC-A


chr4: 52751027
ENST00000650700.1
RASL11B
Intron
SCLC-A


chr4: 52751034
ENST00000650700.1
RASL11B
Intron
SCLC-A


chr4: 52751037
ENST00000650700.1
RASL11B
Intron
SCLC-A


chr4: 52751038
ENST00000650700.1
RASL11B
Intron
SCLC-A


chr4: 52751045
ENST00000650700.1
RASL11B
Intron
SCLC-A


chr4: 52751058
ENST00000650700.1
RASL11B
Intron
SCLC-A


chr4: 52751061
ENST00000650700.1
RASL11B
Intron
SCLC-A


chr4: 52751085
ENST00000650700.1
RASL11B
Intron
SCLC-A


chr4: 52751101
ENST00000650700.1
RASL11B
Intron
SCLC-A


chr4: 140100143
ENST00000502696.1
MAML3
Intron
SCLC-A


chr4: 140100232
ENST00000502696.1
MAML3
Intron
SCLC-A


chr4: 140100233
ENST00000502696.1
MAML3
Intron
SCLC-A


chr4: 140100239
ENST00000502696.1
MAML3
Intron
SCLC-A


chr4: 159676788
ENST00000513718.2
LINC02233
Intron
SCLC-A


chr4: 159676802
ENST00000513718.2
LINC02233
Intron
SCLC-A


chr4: 159676803
ENST00000513718.2
LINC02233
Intron
SCLC-A


chr4: 159676810
ENST00000513718.2
LINC02233
Intron
SCLC-A


chr4: 159676819
ENST00000513718.2
LINC02233
Intron
SCLC-A


chr4: 159733646
ENST00000513718.2
LINC02233
Intron
SCLC-A


chr5: 1219558
ENST00000515652.5
SLC6A19
Exon
SCLC-A


chr5: 64714761
ENST00000509189.5
SHISAL2B
Intron
SCLC-A


chr5: 64714782
ENST00000509189.5
SHISAL2B
Intron
SCLC-A


chr5: 64714797
ENST00000509189.5
SHISAL2B
Intron
SCLC-A


chr5: 64714815
ENST00000509189.5
SHISAL2B
Intron
SCLC-A


chr5: 64714885
ENST00000509189.5
SHISAL2B
Intron
SCLC-A


chr5: 64714900
ENST00000509189.5
SHISAL2B
Intron
SCLC-A


chr5: 64714901
ENST00000509189.5
SHISAL2B
Intron
SCLC-A


chr5: 64714906
ENST00000509189.5
SHISAL2B
Intron
SCLC-A


chr5: 64714907
ENST00000509189.5
SHISAL2B
Intron
SCLC-A


chr5: 64714911
ENST00000509189.5
SHISAL2B
Intron
SCLC-A


chr5: 72120886
ENST00000512974.5
MAP1B
Intron
SCLC-A


chr5: 76819971
ENST00000514165.1
F2RL1
Intron
SCLC-A


chr5: 76819981
ENST00000514165.1
F2RL1
Intron
SCLC-A


chr5: 76819985
ENST00000514165.1
F2RL1
Intron
SCLC-A


chr5: 77848149
ENST00000522370.1
TBCA
Intron
SCLC-A


chr5: 93588608
ENST00000327111.8
NR2F1
Intron
SCLC-A


chr5: 95834831
ENST00000514941.1
NA
Intron
SCLC-A


chr5: 95834835
ENST00000514941.1
NA
Intron
SCLC-A


chr5: 95834840
ENST00000514941.1
NA
Intron
SCLC-A


chr5: 95834843
ENST00000514941.1
NA
Intron
SCLC-A


chr5: 95834898
ENST00000514941.1
NA
Intron
SCLC-A


chr5: 95834915
ENST00000514941.1
NA
Exon
SCLC-A


chr5: 95834932
ENST00000514941.1
NA
Exon
SCLC-A


chr5: 95834935
ENST00000514941.1
NA
Exon
SCLC-A


chr5: 95834938
ENST00000514941.1
NA
Exon
SCLC-A


chr5: 135076216
ENST00000624272.3
C5orf66
Intron
SCLC-A


chr5: 135076253
ENST00000624272.3
C5orf66
Intron
SCLC-A


chr5: 148654157
ENST00000519495.1
HTR4
Intron
SCLC-A


chr5: 149271409
ENST00000522685.1
NA
Intron
SCLC-A


chr5: 149271453
ENST00000522685.1
NA
Intron
SCLC-A


chr5: 149732251
ENST00000360453.8
PPARGC1B
Intron
SCLC-A


chr5: 149732314
ENST00000360453.8
PPARGC1B
Intron
SCLC-A


chr5: 149732315
ENST00000360453.8
PPARGC1B
Intron
SCLC-A


chr5: 149732320
ENST00000360453.8
PPARGC1B
Intron
SCLC-A


chr5: 149732321
ENST00000360453.8
PPARGC1B
Intron
SCLC-A


chr5: 149732340
ENST00000360453.8
PPARGC1B
Intron
SCLC-A


chr5: 149732365
ENST00000360453.8
PPARGC1B
Intron
SCLC-A


chr5: 172244917
ENST00000393792.3
UBTD2
Intron
SCLC-A


chr5: 172244971
ENST00000393792.3
UBTD2
Intron
SCLC-A


chr5: 172244980
ENST00000393792.3
UBTD2
Intron
SCLC-A


chr5: 172244981
ENST00000393792.3
UBTD2
Intron
SCLC-A


chr6: 25318584
ENST00000643807.1
CMAHP
Intron
SCLC-A


chr6: 25318617
ENST00000643807.1
CMAHP
Intron
SCLC-A


chr6: 35469349
ENST00000467020.5
RPL10A
Exon
SCLC-A


chr6: 35469398
ENST00000467020.5
RPL10A
Exon
SCLC-A


chr6: 39228312
ENST00000359534.4
KCNK5
Intron
SCLC-A


chr6: 39228531
ENST00000359534.4
KCNK5
Intron
SCLC-A


chr6: 39228564
ENST00000359534.4
KCNK5
Intron
SCLC-A


chr6: 39228565
ENST00000359534.4
KCNK5
Intron
SCLC-A


chr6: 39228656
ENST00000359534.4
KCNK5
Intron
SCLC-A


chr6: 106046585
ENST00000652320.1
PRDM1
Intron
SCLC-A


chr6: 106046699
ENST00000652320.1
PRDM1
Intron
SCLC-A


chr6: 107046096
ENST00000311381.8
MTRES1
Intron
SCLC-A


chr6: 116371874
ENST00000430252.6
DSE
Intron
SCLC-A


chr6: 116371906
ENST00000430252.6
DSE
Intron
SCLC-A


chr6: 134176153
ENST00000367858.9
SGK1
Intron
SCLC-A


chr6: 134176164
ENST00000367858.9
SGK1
Intron
SCLC-A


chr6: 134176193
ENST00000367858.9
SGK1
Intron
SCLC-A


chr6: 134176242
ENST00000367858.9
SGK1
Intron
SCLC-A


chr6: 136923105
ENST00000331858.5
SLC35D3
Intron
SCLC-A


chr6: 136923373
ENST00000331858.5
SLC35D3
Intron
SCLC-A


chr6: 136923389
ENST00000331858.5
SLC35D3
Intron
SCLC-A


chr6: 136923893
ENST00000331858.5
SLC35D3
Exon
SCLC-A


chr6: 136923901
ENST00000331858.5
SLC35D3
Exon
SCLC-A


chr6: 136923905
ENST00000331858.5
SLC35D3
Exon
SCLC-A


chr6: 136923920
ENST00000331858.5
SLC35D3
Exon
SCLC-A


chr6: 136923925
ENST00000331858.5
SLC35D3
Exon
SCLC-A


chr6: 136923936
ENST00000331858.5
SLC35D3
Exon
SCLC-A


chr6: 136923937
ENST00000331858.5
SLC35D3
Exon
SCLC-A


chr6: 136923950
ENST00000331858.5
SLC35D3
Exon
SCLC-A


chr6: 157990685
ENST00000355585.9
SYNJ2
Intron
SCLC-A


chr6: 157990693
ENST00000355585.9
SYNJ2
Intron
SCLC-A


chr6: 157990742
ENST00000355585.9
SYNJ2
Intron
SCLC-A


chr7: 2524983
ENST00000402506.5
LFNG
Intron
SCLC-A


chr7: 2525019
ENST00000402506.5
LFNG
Intron
SCLC-A


chr7: 2525025
ENST00000402506.5
LFNG
Intron
SCLC-A


chr7: 2525181
ENST00000402506.5
LFNG
Intron
SCLC-A


chr7: 2525182
ENST00000402506.5
LFNG
Intron
SCLC-A


chr7: 2525202
ENST00000402506.5
LFNG
Intron
SCLC-A


chr7: 2525203
ENST00000402506.5
LFNG
Intron
SCLC-A


chr7: 2525223
ENST00000493850.1
LFNG
Exon
SCLC-A


chr7: 2525265
ENST00000493850.1
LFNG
Exon
SCLC-A


chr7: 2525284
ENST00000493850.1
LFNG
Exon
SCLC-A


chr7: 2525297
ENST00000493850.1
LFNG
Exon
SCLC-A


chr7: 2525311
ENST00000493850.1
LFNG
Exon
SCLC-A


chr7: 2525548
ENST00000493850.1
LFNG
Exon
SCLC-A


chr7: 2525556
ENST00000493850.1
LFNG
Exon
SCLC-A


chr7: 2525597
ENST00000402506.5
LFNG
Intron
SCLC-A


chr7: 2525617
ENST00000402506.5
LFNG
Intron
SCLC-A


chr7: 2525649
ENST00000402506.5
LFNG
Intron
SCLC-A


chr7: 2525650
ENST00000402506.5
LFNG
Intron
SCLC-A


chr7: 2525685
ENST00000402506.5
LFNG
Exon
SCLC-A


chr7: 2525710
ENST00000402506.5
LFNG
Exon
SCLC-A


chr7: 2525711
ENST00000402506.5
LFNG
Exon
SCLC-A


chr7: 2525714
ENST00000402506.5
LFNG
Exon
SCLC-A


chr7: 2525715
ENST00000402506.5
LFNG
Exon
SCLC-A


chr7: 2525717
ENST00000402506.5
LFNG
Exon
SCLC-A


chr7: 2525718
ENST00000402506.5
LFNG
Exon
SCLC-A


chr7: 2525736
ENST00000402506.5
LFNG
Exon
SCLC-A


chr7: 44150961
ENST00000673284.1
GCK
Exon
SCLC-A


chr7: 44150970
ENST00000673284.1
GCK
Exon
SCLC-A


chr7: 44151070
ENST00000673284.1
GCK
Exon
SCLC-A


chr7: 44151088
ENST00000437084.1
GCK
Intron
SCLC-A


chr7: 44151089
ENST00000437084.1
GCK
Intron
SCLC-A


chr7: 44151119
ENST00000437084.1
GCK
Intron
SCLC-A


chr7: 44151120
ENST00000437084.1
GCK
Intron
SCLC-A


chr7: 44151141
ENST00000437084.1
GCK
Intron
SCLC-A


chr7: 44151294
ENST00000437084.1
GCK
Intron
SCLC-A


chr7: 44151331
ENST00000437084.1
GCK
Intron
SCLC-A


chr7: 50793906
ENST00000644769.1
GRB10
Promoter
SCLC-A


chr7: 50793910
ENST00000644769.1
GRB10
Promoter
SCLC-A


chr7: 50793930
ENST00000644769.1
GRB10
Promoter
SCLC-A


chr7: 50793941
ENST00000644769.1
GRB10
Promoter
SCLC-A


chr7: 50793958
ENST00000644769.1
GRB10
Promoter
SCLC-A


chr7: 66147068
ENST00000435524.2
NA
Intron
SCLC-A


chr7: 66147069
ENST00000435524.2
NA
Intron
SCLC-A


chr7: 66147070
ENST00000435524.2
NA
Intron
SCLC-A


chr7: 93922083
ENST00000248564.6
GNG11
Exon
SCLC-A


chr7: 93922100
ENST00000248564.6
GNG11
Exon
SCLC-A


chr7: 93922205
ENST00000248564.6
GNG11
Exon
SCLC-A


chr7: 95597100
ENST00000665332.1
NA
Intron
SCLC-A


chr7: 100493657
ENST00000300179.7
NYAP1
Exon
SCLC-A


chr7: 100493663
ENST00000300179.7
NYAP1
Exon
SCLC-A


chr7: 100494045
ENST00000300179.7
NYAP1
Exon
SCLC-A


chr7: 100583557
ENST00000310300.11
LRCH4
Intron
SCLC-A


chr7: 128940692
ENST00000652525.1
IRF5
Intron
SCLC-A


chr7: 149879452
ENST00000464939.1
ATP6V0E2-AS1
Intron
SCLC-A


chr7: 149879540
ENST00000464939.1
ATP6V0E2-AS1
Intron
SCLC-A


chr7: 149879687
ENST00000464939.1
ATP6V0E2-AS1
Intron
SCLC-A


chr7: 151090666
ENST00000463381.5
AGAP3
Intron
SCLC-A


chr7: 151090681
ENST00000463381.5
AGAP3
Intron
SCLC-A


chr7: 151090682
ENST00000463381.5
AGAP3
Intron
SCLC-A


chr7: 151090719
ENST00000463381.5
AGAP3
Intron
SCLC-A


chr7: 151090725
ENST00000463381.5
AGAP3
Intron
SCLC-A


chr7: 151090726
ENST00000463381.5
AGAP3
Intron
SCLC-A


chr7: 157501293
ENST00000449903.1
NA
Promoter
SCLC-A


chr7: 157501364
ENST00000669906.1
NA
Promoter
SCLC-A


chr7: 157542990
ENST00000389413.7
PTPRN2
Intron
SCLC-A


chr7: 157566762
ENST00000389413.7
PTPRN2
Intron
SCLC-A


chr7: 157615909
ENST00000389413.7
PTPRN2
Intron
SCLC-A


chr7: 157678656
ENST00000389413.7
PTPRN2
Intron
SCLC-A


chr8: 28703207
ENST00000523149.5
EXTL3
Intron
SCLC-A


chr8: 41835983
ENST00000265709.13
ANK1
Intron
SCLC-A


chr8: 41835994
ENST00000265709.13
ANK1
Intron
SCLC-A


chr8: 80301230
ENST00000656157.1
NA
Intron
SCLC-A


chr8: 80301265
ENST00000656157.1
NA
Intron
SCLC-A


chr8: 80301272
ENST00000656157.1
NA
Intron
SCLC-A


chr8: 80301325
ENST00000656157.1
NA
Intron
SCLC-A


chr8: 80301357
ENST00000656157.1
NA
Intron
SCLC-A


chr8: 80301489
ENST00000656157.1
NA
Intron
SCLC-A


chr8: 81631134
ENST00000522318.1
IMPA1P1
Exon
SCLC-A


chr8: 81631136
ENST00000522318.1
IMPA1P1
Promoter
SCLC-A


chr8: 81631189
ENST00000522318.1
IMPA1P1
Promoter
SCLC-A


chr8: 81631196
ENST00000522318.1
IMPA1P1
Promoter
SCLC-A


chr8: 134499858
ENST00000429442.6
ZFAT
Intron
SCLC-A


chr8: 138855526
ENST00000303045.11
COL22A1
Intron
SCLC-A


chr8: 139604660
ENST00000650269.1
KCNK9
Intron
SCLC-A


chr8: 139674334
ENST00000522317.5
KCNK9
Intron
SCLC-A


chr8: 142254143
ENST00000524325.6
TSNARE1
Intron
SCLC-A


chr8: 142254185
ENST00000524325.6
TSNARE1
Intron
SCLC-A


chr8: 142254280
ENST00000524325.6
TSNARE1
Intron
SCLC-A


chr8: 142254302
ENST00000524325.6
TSNARE1
Intron
SCLC-A


chr8: 144810882
ENST00000525105.5
ZNF517
Exon
SCLC-A


chr8: 144810898
ENST00000525105.5
ZNF517
Exon
SCLC-A


chr8: 144810916
ENST00000525105.5
ZNF517
Exon
SCLC-A


chr8: 144810920
ENST00000525105.5
ZNF517
Exon
SCLC-A


chr9: 93299724
ENST00000411624.5
WNK2
Intron
SCLC-A


chr9: 93299816
ENST00000411624.5
WNK2
Intron
SCLC-A


chr9: 93299821
ENST00000411624.5
WNK2
Intron
SCLC-A


chr9: 93299844
ENST00000411624.5
WNK2
Intron
SCLC-A


chr9: 114347854
ENST00000307564.8
AKNA
Exon
SCLC-A


chr9: 123390810
ENST00000373624.6
DENND1A
Intron
SCLC-A


chr9: 123390838
ENST00000373624.6
DENND1A
Intron
SCLC-A


chr9: 129495781
ENST00000653047.1
LINC00963
Intron
SCLC-A


chr9: 131579248
ENST00000372189.7
RAPGEF1
Exon
SCLC-A


chr9: 131579298
ENST00000372189.7
RAPGEF1
Exon
SCLC-A


chr9: 131579299
ENST00000372189.7
RAPGEF1
Exon
SCLC-A


chr9: 131598232
ENST00000372189.7
RAPGEF1
Exon
SCLC-A


chr9: 131598281
ENST00000372189.7
RAPGEF1
Exon
SCLC-A


chr9: 131598349
ENST00000372189.7
RAPGEF1
Intron
SCLC-A


chr9: 136231817
ENST00000358701.9
QSOX2
Intron
SCLC-A


chr9: 136231853
ENST00000358701.9
QSOX2
Intron
SCLC-A


chr9: 136326076
ENST00000573103.2
DKFZP434A062
Exon
SCLC-A


chr9: 136326115
ENST00000573103.2
DKFZP434A062
Exon
SCLC-A


chr9: 136326179
ENST00000573103.2
DKFZP434A062
Exon
SCLC-A


chr9: 136326197
ENST00000573103.2
DKFZP434A062
Exon
SCLC-A


chr9: 136326251
ENST00000573103.2
DKFZP434A062
Exon
SCLC-A


chr9: 136326252
ENST00000573103.2
DKFZP434A062
Exon
SCLC-A


chr9: 136326273
ENST00000573103.2
DKFZP434A062
Exon
SCLC-A


chr9: 136326274
ENST00000573103.2
DKFZP434A062
Exon
SCLC-A


chr9: 136326278
ENST00000573103.2
DKFZP434A062
Exon
SCLC-A


chr9: 136326279
ENST00000573103.2
DKFZP434A062
Exon
SCLC-A


chr9: 137877782
ENST00000371390.1
LOC100133077
Intron
SCLC-A
















TABLE 21







Additional methylation sites associated with the SCLC-N subtype











Methylation Site
Transcript_ID
Gene_Symbol
Gene_Region
Subtype





chr1: 1348040
ENST00000378891.9
DVL1
Intron
SCLC-N


chr1: 2318110
ENST00000661319.1
NA
Intron
SCLC-N


chr1: 3526032
ENST00000356575.9
MEGF6
Intron
SCLC-N


chr1: 5917369
ENST00000378169.7
NPHP4
Intron
SCLC-N


chr1: 5917443
ENST00000378169.7
NPHP4
Intron
SCLC-N


chr1: 5917479
ENST00000378169.7
NPHP4
Intron
SCLC-N


chr1: 6095341
ENST00000652911.1
KCNAB2
Exon
SCLC-N


chr1: 6378302
ENST00000608083.5
ACOT7
Intron
SCLC-N


chr1: 6378308
ENST00000608083.5
ACOT7
Intron
SCLC-N


chr1: 6907148
ENST00000303635.12
CAMTA1
Intron
SCLC-N


chr1: 7374098
ENST00000303635.12
CAMTA1
Intron
SCLC-N


chr1: 7455576
ENST00000303635.12
CAMTA1
Intron
SCLC-N


chr1: 7455653
ENST00000303635.12
CAMTA1
Intron
SCLC-N


chr1: 7455816
ENST00000303635.12
CAMTA1
Intron
SCLC-N


chr1: 7455821
ENST00000303635.12
CAMTA1
Intron
SCLC-N


chr1: 8681153
ENST00000656437.1
RERE
Intron
SCLC-N


chr1: 9688039
ENST00000377346.9
PIK3CD
Intron
SCLC-N


chr1: 10658362
ENST00000377022.8
CASZ1
Intron
SCLC-N


chr1: 10658432
ENST00000377022.8
CASZ1
Intron
SCLC-N


chr1: 10658482
ENST00000377022.8
CASZ1
Intron
SCLC-N


chr1: 10658483
ENST00000377022.8
CASZ1
Intron
SCLC-N


chr1: 10658549
ENST00000492173.1
CASZ1
Exon
SCLC-N


chr1: 10658573
ENST00000492173.1
CASZ1
Exon
SCLC-N


chr1: 10658604
ENST00000377022.8
CASZ1
Intron
SCLC-N


chr1: 10658877
ENST00000377022.8
CASZ1
Intron
SCLC-N


chr1: 10704628
ENST00000377022.8
CASZ1
Intron
SCLC-N


chr1: 10948360
ENST00000476357.1
C1orf127
Exon
SCLC-N


chr1: 10948392
ENST00000476357.1
C1orf127
Exon
SCLC-N


chr1: 10948648
ENST00000476357.1
C1orf127
Exon
SCLC-N


chr1: 10948809
ENST00000476357.1
C1orf127
Exon
SCLC-N


chr1: 15735083
ENST00000453804.1
NA
Intron
SCLC-N


chr1: 15765675
ENST00000502739.5
FBLIM1
Intron
SCLC-N


chr1: 15765717
ENST00000502739.5
FBLIM1
Intron
SCLC-N


chr1: 18482237
ENST00000400664.2
KLHDC7A
Exon
SCLC-N


chr1: 18482266
ENST00000400664.2
KLHDC7A
Exon
SCLC-N


chr1: 18482380
ENST00000400664.2
KLHDC7A
Exon
SCLC-N


chr1: 21428308
ENST00000453025.1
NA
Promoter
SCLC-N


chr1: 21428311
ENST00000453025.1
NA
Promoter
SCLC-N


chr1: 25771501
ENST00000611903.4
MAN1C1
Intron
SCLC-N


chr1: 25771542
ENST00000611903.4
MAN1C1
Intron
SCLC-N


chr1: 25771803
ENST00000496532.5
MAN1C1
Promoter
SCLC-N


chr1: 26162435
ENST00000374268.5
FAM110D
Exon
SCLC-N


chr1: 26162459
ENST00000374268.5
FAM110D
Exon
SCLC-N


chr1: 28869066
ENST00000234961.7
OPRD1
Exon
SCLC-N


chr1: 28869195
ENST00000234961.7
OPRD1
Exon
SCLC-N


chr1: 28869207
ENST00000234961.7
OPRD1
Exon
SCLC-N


chr1: 28869208
ENST00000234961.7
OPRD1
Exon
SCLC-N


chr1: 28869229
ENST00000234961.7
OPRD1
Exon
SCLC-N


chr1: 28869230
ENST00000234961.7
OPRD1
Exon
SCLC-N


chr1: 28869236
ENST00000234961.7
OPRD1
Exon
SCLC-N


chr1: 28869237
ENST00000234961.7
OPRD1
Exon
SCLC-N


chr1: 28869354
ENST00000234961.7
OPRD1
Exon
SCLC-N


chr1: 28869382
ENST00000234961.7
OPRD1
Exon
SCLC-N


chr1: 28869383
ENST00000234961.7
OPRD1
Exon
SCLC-N


chr1: 31626915
ENST00000373705.1
HCRTR1
Intron
SCLC-N


chr1: 31626982
ENST00000373705.1
HCRTR1
Intron
SCLC-N


chr1: 42735278
ENST00000539749.5
CLDN19
Exon
SCLC-N


chr1: 42735300
ENST00000539749.5
CLDN19
Exon
SCLC-N


chr1: 42735392
ENST00000539749.5
CLDN19
Exon
SCLC-N


chr1: 42735571
ENST00000539749.5
CLDN19
Exon
SCLC-N


chr1: 44637731
ENST00000355387.6
RNF220
Intron
SCLC-N


chr1: 46285986
ENST00000498402.2
LRRC41
Exon
SCLC-N


chr1: 46285995
ENST00000498402.2
LRRC41
Exon
SCLC-N


chr1: 50421427
ENST00000418121.5
DMRTA2
Exon
SCLC-N


chr1: 50421430
ENST00000418121.5
DMRTA2
Exon
SCLC-N


chr1: 50421439
ENST00000418121.5
DMRTA2
Exon
SCLC-N


chr1: 50421445
ENST00000418121.5
DMRTA2
Exon
SCLC-N


chr1: 50421447
ENST00000418121.5
DMRTA2
Exon
SCLC-N


chr1: 50421454
ENST00000418121.5
DMRTA2
Exon
SCLC-N


chr1: 50421466
ENST00000418121.5
DMRTA2
Exon
SCLC-N


chr1: 50421472
ENST00000418121.5
DMRTA2
Exon
SCLC-N


chr1: 50421475
ENST00000418121.5
DMRTA2
Exon
SCLC-N


chr1: 50421483
ENST00000418121.5
DMRTA2
Exon
SCLC-N


chr1: 50421484
ENST00000418121.5
DMRTA2
Exon
SCLC-N


chr1: 50421489
ENST00000418121.5
DMRTA2
Exon
SCLC-N


chr1: 50421490
ENST00000418121.5
DMRTA2
Exon
SCLC-N


chr1: 50421501
ENST00000418121.5
DMRTA2
Exon
SCLC-N


chr1: 50421504
ENST00000418121.5
DMRTA2
Exon
SCLC-N


chr1: 55063332
ENST00000302118.5
PCSK9
Intron
SCLC-N


chr1: 55063374
ENST00000302118.5
PCSK9
Exon
SCLC-N


chr1: 55063384
ENST00000302118.5
PCSK9
Exon
SCLC-N


chr1: 55063449
ENST00000302118.5
PCSK9
Exon
SCLC-N


chr1: 60897215
ENST00000371191.5
NFIA
Intron
SCLC-N


chr1: 61052398
ENST00000371191.5
NFIA
Intron
SCLC-N


chr1: 88682776
ENST00000458097.5
PKN2-AS1
Intron
SCLC-N


chr1: 90841513
ENST00000669273.1
LINC02609
Intron
SCLC-N


chr1: 112871178
ENST00000658577.1
NA
Intron
SCLC-N


chr1: 115655113
ENST00000355485.7
VANGL1
Intron
SCLC-N


chr1: 154842667
ENST00000271915.9
KCNN3
Intron
SCLC-N


chr1: 159011154
ENST00000566111.5
IFI16
Intron
SCLC-N


chr1: 161198356
ENST00000479948.5
NDUFS2
Intron
SCLC-N


chr1: 161198378
ENST00000479948.5
NDUFS2
Intron
SCLC-N


chr1: 161198400
ENST00000479948.5
NDUFS2
Intron
SCLC-N


chr1: 161198403
ENST00000479948.5
NDUFS2
Intron
SCLC-N


chr1: 161198404
ENST00000479948.5
NDUFS2
Intron
SCLC-N


chr1: 162373995
ENST00000431696.1
NOS1AP
Intron
SCLC-N


chr1: 180174185
ENST00000367602.8
QSOX1
Intron
SCLC-N


chr1: 180182136
ENST00000367602.8
QSOX1
Intron
SCLC-N


chr1: 180182208
ENST00000367602.8
QSOX1
Exon
SCLC-N


chr1: 180182213
ENST00000367602.8
QSOX1
Exon
SCLC-N


chr1: 180182264
ENST00000367602.8
QSOX1
Exon
SCLC-N


chr1: 180182292
ENST00000367602.8
QSOX1
Exon
SCLC-N


chr1: 180183034
ENST00000367602.8
QSOX1
Intron
SCLC-N


chr1: 180183061
ENST00000367602.8
QSOX1
Intron
SCLC-N


chr1: 180183067
ENST00000367602.8
QSOX1
Intron
SCLC-N


chr1: 180183068
ENST00000367602.8
QSOX1
Intron
SCLC-N


chr1: 180183222
ENST00000367602.8
QSOX1
Intron
SCLC-N


chr1: 180460155
ENST00000642319.1
LHX4-AS1
Intron
SCLC-N


chr1: 180941072
ENST00000461346.1
KIAA1614
Promoter
SCLC-N


chr1: 201942012
ENST00000367288.5
LMOD1
Intron
SCLC-N


chr1: 204447512
ENST00000367187.7
PIK3C2B
Exon
SCLC-N


chr1: 204481681
ENST00000415899.1
PIK3C2B
Intron
SCLC-N


chr1: 204481806
ENST00000415899.1
PIK3C2B
Intron
SCLC-N


chr1: 205064748
ENST00000636641.2
CNTN2
Promoter
SCLC-N


chr1: 205519116
ENST00000507067.1
CDK18
Intron
SCLC-N


chr1: 206490930
ENST00000581977.7
IKBKE
Intron
SCLC-N


chr1: 206702548
ENST00000294981.8
MAPKAPK2
Intron
SCLC-N


chr1: 207848368
ENST00000637970.1
MIR29B2CHG
Intron
SCLC-N


chr1: 207848391
ENST00000637970.1
MIR29B2CHG
Intron
SCLC-N


chr1: 207848493
ENST00000637970.1
MIR29B2CHG
Intron
SCLC-N


chr1: 208120134
ENST00000367033.4
PLXNA2
Intron
SCLC-N


chr1: 208231439
ENST00000367033.4
PLXNA2
Intron
SCLC-N


chr1: 212916596
ENST00000632866.1
NA
Promoter
SCLC-N


chr1: 212981590
ENST00000366966.6
VASH2
Intron
SCLC-N


chr1: 212982124
ENST00000366966.6
VASH2
Intron
SCLC-N


chr1: 212982320
ENST00000366966.6
VASH2
Intron
SCLC-N


chr1: 214551221
ENST00000366956.10
PTPN14
UTR5
SCLC-N


chr1: 226540981
ENST00000671364.1
NA
Intron
SCLC-N


chr1: 226589203
ENST00000366788.8
STUM
Intron
SCLC-N


chr1: 226589217
ENST00000366788.8
STUM
Intron
SCLC-N


chr1: 231693853
ENST00000602873.5
DISC1
Intron
SCLC-N


chr1: 231693854
ENST00000602873.5
DISC1
Intron
SCLC-N


chr1: 231693861
ENST00000602873.5
DISC1
Intron
SCLC-N


chr1: 231693867
ENST00000602873.5
DISC1
Intron
SCLC-N


chr1: 231693870
ENST00000602873.5
DISC1
Intron
SCLC-N


chr1: 231693879
ENST00000602873.5
DISC1
Intron
SCLC-N


chr1: 231693880
ENST00000602873.5
DISC1
Intron
SCLC-N


chr1: 231693886
ENST00000602873.5
DISC1
Intron
SCLC-N


chr1: 231693887
ENST00000602873.5
DISC1
Intron
SCLC-N


chr1: 231693921
ENST00000602873.5
DISC1
Intron
SCLC-N


chr1: 231693994
ENST00000602873.5
DISC1
Intron
SCLC-N


chr1: 231694044
ENST00000602873.5
DISC1
Intron
SCLC-N


chr1: 231694399
ENST00000602873.5
DISC1
Intron
SCLC-N


chr1: 231694419
ENST00000602873.5
DISC1
Intron
SCLC-N


chr1: 234235867
ENST00000366618.8
SLC35F3
Intron
SCLC-N


chr1: 234235881
ENST00000366618.8
SLC35F3
Intron
SCLC-N


chr1: 245212635
ENST00000407071.7
KIF26B
Intron
SCLC-N


chr10: 1650866
ENST00000381312.6
ADARB2
Intron
SCLC-N


chr10: 1650867
ENST00000381312.6
ADARB2
Intron
SCLC-N


chr10: 1650882
ENST00000381312.6
ADARB2
Intron
SCLC-N


chr10: 1650883
ENST00000381312.6
ADARB2
Intron
SCLC-N


chr10: 3781749
ENST00000173785.4
KLF6
Intron
SCLC-N


chr10: 3781785
ENST00000173785.4
KLF6
Intron
SCLC-N


chr10: 3782363
ENST00000173785.4
KLF6
Promoter
SCLC-N


chr10: 3782364
ENST00000173785.4
KLF6
Promoter
SCLC-N


chr10: 3782374
ENST00000173785.4
KLF6
Promoter
SCLC-N


chr10: 23960136
ENST00000376462.5
KIAA1217
Intron
SCLC-N


chr10: 23960137
ENST00000376462.5
KIAA1217
Intron
SCLC-N


chr10: 23960206
ENST00000376462.5
KIAA1217
Intron
SCLC-N


chr10: 24300973
ENST00000376462.5
KIAA1217
Intron
SCLC-N


chr10: 51123578
ENST00000401604.8
PRKG1
Intron
SCLC-N


chr10: 51123611
ENST00000401604.8
PRKG1
Intron
SCLC-N


chr10: 69374479
ENST00000436817.6
HK1
Intron
SCLC-N


chr10: 69375951
ENST00000436817.6
HK1
Intron
SCLC-N


chr10: 74134133
ENST00000355264.8
AP3M1
Exon
SCLC-N


chr10: 99879892
ENST00000543621.6
DNMBP
Exon
SCLC-N


chr10: 102294627
ENST00000369983.3
GBF1
Intron
SCLC-N


chr10: 102294628
ENST00000369983.3
GBF1
Intron
SCLC-N


chr10: 112952176
ENST00000534894.5
TCF7L2
Intron
SCLC-N


chr10: 116275192
ENST00000648277.1
NA
Exon
SCLC-N


chr10: 119282537
ENST00000392870.3
GRK5
Intron
SCLC-N


chr10: 119282564
ENST00000392870.3
GRK5
Intron
SCLC-N


chr10: 119282662
ENST00000392870.3
GRK5
Intron
SCLC-N


chr10: 121580588
ENST00000356226.8
FGFR2
Intron
SCLC-N


chr10: 121580759
ENST00000356226.8
FGFR2
Intron
SCLC-N


chr10: 124478693
ENST00000368842.10
LHPP
Intron
SCLC-N


chr10: 124478697
ENST00000368842.10
LHPP
Intron
SCLC-N


chr10: 124478718
ENST00000368842.10
LHPP
Intron
SCLC-N


chr10: 127736157
ENST00000623953.1
NA
Exon
SCLC-N


chr10: 127736181
ENST00000623953.1
NA
Exon
SCLC-N


chr10: 132811036
ENST00000368586.10
CFAP46
Intron
SCLC-N


chr10: 132811041
ENST00000368586.10
CFAP46
Intron
SCLC-N


chr11: 888359
ENST00000526714.5
CHID1
Intron
SCLC-N


chr11: 888460
ENST00000526714.5
CHID1
Intron
SCLC-N


chr11: 888461
ENST00000526714.5
CHID1
Intron
SCLC-N


chr11: 888482
ENST00000526714.5
CHID1
Intron
SCLC-N


chr11: 888519
ENST00000526714.5
CHID1
Intron
SCLC-N


chr11: 888547
ENST00000526714.5
CHID1
Intron
SCLC-N


chr11: 888548
ENST00000526714.5
CHID1
Intron
SCLC-N


chr11: 888556
ENST00000526714.5
CHID1
Intron
SCLC-N


chr11: 888557
ENST00000526714.5
CHID1
Intron
SCLC-N


chr11: 888561
ENST00000526714.5
CHID1
Intron
SCLC-N


chr11: 888562
ENST00000526714.5
CHID1
Intron
SCLC-N


chr11: 888597
ENST00000526714.5
CHID1
Intron
SCLC-N


chr11: 1450652
ENST00000544817.5
BRSK2
Promoter
SCLC-N


chr11: 1450687
ENST00000308219.13
BRSK2
Exon
SCLC-N


chr11: 1746746
ENST00000636579.1
IFITM10
Intron
SCLC-N


chr11: 2718090
ENST00000155840.11
KCNQ1
Intron
SCLC-N


chr11: 17449179
ENST00000645744.1
ABCC8
Intron
SCLC-N


chr11: 17449216
ENST00000645744.1
ABCC8
Intron
SCLC-N


chr11: 17449222
ENST00000645744.1
ABCC8
Intron
SCLC-N


chr11: 19832413
ENST00000360655.8
NAV2
Intron
SCLC-N


chr11: 19832533
ENST00000360655.8
NAV2
Exon
SCLC-N


chr11: 22338192
ENST00000263160.4
SLC17A6
Promoter
SCLC-N


chr11: 22338261
ENST00000263160.4
SLC17A6
Promoter
SCLC-N


chr11: 31804635
ENST00000638965.1
PAX6
Intron
SCLC-N


chr11: 31804694
ENST00000638965.1
PAX6
Intron
SCLC-N


chr11: 31805187
ENST00000638965.1
PAX6
Intron
SCLC-N


chr11: 31805192
ENST00000638965.1
PAX6
Intron
SCLC-N


chr11: 31805210
ENST00000638965.1
PAX6
Intron
SCLC-N


chr11: 31805286
ENST00000638965.1
PAX6
Intron
SCLC-N


chr11: 31805292
ENST00000638965.1
PAX6
Intron
SCLC-N


chr11: 31805302
ENST00000638965.1
PAX6
Intron
SCLC-N


chr11: 31805419
ENST00000638965.1
PAX6
Intron
SCLC-N


chr11: 31805474
ENST00000638965.1
PAX6
Intron
SCLC-N


chr11: 31805500
ENST00000638965.1
PAX6
Intron
SCLC-N


chr11: 31820660
ENST00000530348.5
RCN1
Intron
SCLC-N


chr11: 32166325
ENST00000419556.2
NA
Intron
SCLC-N


chr11: 32311336
ENST00000525689.2
NA
Intron
SCLC-N


chr11: 34502672
ENST00000429939.6
ELF5
Intron
SCLC-N


chr11: 59762173
ENST00000641815.1
STX3
Intron
SCLC-N


chr11: 59762256
ENST00000641815.1
STX3
Intron
SCLC-N


chr11: 60411065
ENST00000531787.5
MS4A14
Intron
SCLC-N


chr11: 60411092
ENST00000531787.5
MS4A14
Intron
SCLC-N


chr11: 60411097
ENST00000531787.5
MS4A14
Intron
SCLC-N


chr11: 60524906
ENST00000527948.1
MS4A13
Intron
SCLC-N


chr11: 60524907
ENST00000527948.1
MS4A13
Intron
SCLC-N


chr11: 60524912
ENST00000527948.1
MS4A13
Intron
SCLC-N


chr11: 61696210
ENST00000257215.10
DAGLA
Intron
SCLC-N


chr11: 61696297
ENST00000257215.10
DAGLA
Intron
SCLC-N


chr11: 61696393
ENST00000257215.10
DAGLA
Intron
SCLC-N


chr11: 72584678
ENST00000441209.6
PDE2A
Promoter
SCLC-N


chr11: 72584886
ENST00000441209.6
PDE2A
Promoter
SCLC-N


chr11: 72584892
ENST00000441209.6
PDE2A
Promoter
SCLC-N


chr11: 72584895
ENST00000441209.6
PDE2A
Promoter
SCLC-N


chr11: 121111283
ENST00000645041.1
TBCEL
Intron
SCLC-N


chr11: 126165892
ENST00000532357.1
NA
Intron
SCLC-N


chr11: 126165940
ENST00000532357.1
NA
Intron
SCLC-N


chr11: 126165948
ENST00000532357.1
NA
Intron
SCLC-N


chr11: 126165949
ENST00000532357.1
NA
Intron
SCLC-N


chr11: 126356903
ENST00000227495.10
ST3GAL4
Intron
SCLC-N


chr11: 126585523
ENST00000548204.1
NA
Intron
SCLC-N


chr11: 126585530
ENST00000548204.1
NA
Intron
SCLC-N


chr11: 126749417
ENST00000525144.7
KIRREL3
Intron
SCLC-N


chr11: 126749456
ENST00000525144.7
KIRREL3
Intron
SCLC-N


chr11: 128913895
ENST00000529694.6
KCNJ5
Intron
SCLC-N


chr12: 1500501
ENST00000515614.3
LINC00942
Promoter
SCLC-N


chr12: 1500510
ENST00000515614.3
LINC00942
Promoter
SCLC-N


chr12: 1500511
ENST00000515614.3
LINC00942
Promoter
SCLC-N


chr12: 1822018
ENST00000444595.6
CACNA2D4
Intron
SCLC-N


chr12: 6633693
ENST00000329858.9
LPAR5
Intron
SCLC-N


chr12: 30988264
ENST00000546076.5
TSPAN11
Intron
SCLC-N


chr12: 42479754
ENST00000639958.1
PRICKLE1
Intron
SCLC-N


chr12: 42497409
ENST00000639958.1
PRICKLE1
Intron
SCLC-N


chr12: 42497410
ENST00000639958.1
PRICKLE1
Intron
SCLC-N


chr12: 51377533
ENST00000543196.6
GALNT6
Intron
SCLC-N


chr12: 57225138
ENST00000349394.6
NXPH4
Exon
SCLC-N


chr12: 77047970
ENST00000416496.6
E2F7
Intron
SCLC-N


chr12: 96233859
ENST00000552142.5
ELK3
Intron
SCLC-N


chr12: 96234054
ENST00000552142.5
ELK3
Intron
SCLC-N


chr12: 97465331
ENST00000538559.6
RMST
Intron
SCLC-N


chr12: 97596152
ENST00000639121.1
RMST
Intron
SCLC-N


chr12: 108804526
ENST00000546433.5
SSH1
Intron
SCLC-N


chr12: 112946864
ENST00000552784.1
NA
Intron
SCLC-N


chr12: 112946932
ENST00000552784.1
NA
Intron
SCLC-N


chr12: 112946963
ENST00000552784.1
NA
Intron
SCLC-N


chr12: 122355274
ENST00000541410.1
CLIP1
Exon
SCLC-N


chr12: 124463768
ENST00000448008.1
NCOR2
Intron
SCLC-N


chr12: 130463309
ENST00000261655.8
RIMBP2
Intron
SCLC-N


chr12: 130463326
ENST00000261655.8
RIMBP2
Intron
SCLC-N


chr13: 98214193
ENST00000595437.5
FARP1
Intron
SCLC-N


chr13: 109495155
ENST00000650264.1
NA
Intron
SCLC-N


chr13: 111598392
ENST00000375713.1
NA
Intron
SCLC-N


chr13: 111598399
ENST00000375713.1
NA
Intron
SCLC-N


chr14: 24158185
ENST00000362934.1
NA
Promoter
SCLC-N


chr14: 74946474
ENST00000555253.1
PGF
Exon
SCLC-N


chr14: 74946478
ENST00000555253.1
PGF
Exon
SCLC-N


chr14: 76396996
ENST00000512784.6
ESRRB
Intron
SCLC-N


chr14: 76397003
ENST00000512784.6
ESRRB
Intron
SCLC-N


chr14: 89284792
ENST00000345097.8
FOXN3
Intron
SCLC-N


chr14: 91170655
ENST00000518649.5
DGLUCY
Intron
SCLC-N


chr14: 91375767
ENST00000389857.11
CCDC88C
Intron
SCLC-N


chr14: 93737728
ENST00000393143.5
PRIMA1
Intron
SCLC-N


chr14: 93752608
ENST00000393143.5
PRIMA1
Intron
SCLC-N


chr14: 94001245
ENST00000444118.5
CCDC197
Exon
SCLC-N


chr14: 102630887
ENST00000262241.7
RCOR1
Intron
SCLC-N


chr14: 103104365
ENST00000560925.5
EXOC3L4
Exon
SCLC-N


chr14: 103104368
ENST00000560925.5
EXOC3L4
Exon
SCLC-N


chr14: 105173746
ENST00000548203.1
JAG2
Intron
SCLC-N


chr15: 28886855
ENST00000561069.5
APBA2
Intron
SCLC-N


chr15: 34580510
ENST00000569100.5
GOLGA8B
Intron
SCLC-N


chr15: 34580589
ENST00000569100.5
GOLGA8B
Intron
SCLC-N


chr15: 40291333
ENST00000559671.5
PLCB2
Promoter
SCLC-N


chr15: 40291340
ENST00000559671.5
PLCB2
Promoter
SCLC-N


chr15: 40291349
ENST00000559671.5
PLCB2
Promoter
SCLC-N


chr15: 40291352
ENST00000559671.5
PLCB2
Promoter
SCLC-N


chr15: 40291354
ENST00000559671.5
PLCB2
Promoter
SCLC-N


chr15: 45187264
ENST00000560034.1
NA
Intron
SCLC-N


chr15: 45187265
ENST00000560034.1
NA
Intron
SCLC-N


chr15: 45187278
ENST00000560034.1
NA
Intron
SCLC-N


chr15: 45187279
ENST00000560034.1
NA
Intron
SCLC-N


chr15: 45187312
ENST00000560034.1
NA
Intron
SCLC-N


chr15: 58065916
ENST00000558239.5
ALDH1A2
Intron
SCLC-N


chr15: 65271021
ENST00000444347.2
PARP16
Intron
SCLC-N


chr15: 67829883
ENST00000341418.10
SKOR1
Intron
SCLC-N


chr15: 67829885
ENST00000341418.10
SKOR1
Intron
SCLC-N


chr15: 67829889
ENST00000341418.10
SKOR1
Intron
SCLC-N


chr15: 67829891
ENST00000341418.10
SKOR1
Intron
SCLC-N


chr15: 67829908
ENST00000341418.10
SKOR1
Intron
SCLC-N


chr15: 67829910
ENST00000341418.10
SKOR1
Intron
SCLC-N


chr15: 67829912
ENST00000341418.10
SKOR1
Intron
SCLC-N


chr15: 74826515
ENST00000564823.1
CPLX3
Exon
SCLC-N


chr15: 74826550
ENST00000564823.1
CPLX3
Exon
SCLC-N


chr15: 74826559
ENST00000564823.1
CPLX3
Exon
SCLC-N


chr15: 74826560
ENST00000564823.1
CPLX3
Exon
SCLC-N


chr15: 74826565
ENST00000564823.1
CPLX3
Exon
SCLC-N


chr15: 74826566
ENST00000564823.1
CPLX3
Exon
SCLC-N


chr15: 74826569
ENST00000564823.1
CPLX3
Exon
SCLC-N


chr15: 74826570
ENST00000564823.1
CPLX3
Exon
SCLC-N


chr15: 74826572
ENST00000564823.1
CPLX3
Exon
SCLC-N


chr15: 74826573
ENST00000564823.1
CPLX3
Exon
SCLC-N


chr15: 74826577
ENST00000564823.1
CPLX3
Exon
SCLC-N


chr15: 74826586
ENST00000564823.1
CPLX3
Exon
SCLC-N


chr15: 74826587
ENST00000564823.1
CPLX3
Exon
SCLC-N


chr15: 74826593
ENST00000564823.1
CPLX3
Exon
SCLC-N


chr15: 74826594
ENST00000564823.1
CPLX3
Exon
SCLC-N


chr15: 74826595
ENST00000564823.1
CPLX3
Exon
SCLC-N


chr15: 74826596
ENST00000564823.1
CPLX3
Exon
SCLC-N


chr15: 74826601
ENST00000564823.1
CPLX3
Exon
SCLC-N


chr15: 74826617
ENST00000564823.1
CPLX3
Exon
SCLC-N


chr15: 74826618
ENST00000564823.1
CPLX3
Exon
SCLC-N


chr15: 74826619
ENST00000564823.1
CPLX3
Exon
SCLC-N


chr15: 74826620
ENST00000564823.1
CPLX3
Exon
SCLC-N


chr15: 74826642
ENST00000564823.1
CPLX3
Exon
SCLC-N


chr15: 74826693
ENST00000564823.1
CPLX3
Exon
SCLC-N


chr15: 74826696
ENST00000564823.1
CPLX3
Exon
SCLC-N


chr15: 74826697
ENST00000564823.1
CPLX3
Exon
SCLC-N


chr15: 74826708
ENST00000564823.1
CPLX3
Exon
SCLC-N


chr15: 80445702
ENST00000529181.1
ARNT2
Intron
SCLC-N


chr15: 89815305
ENST00000300060.7
ANPEP
Promoter
SCLC-N


chr15: 92819642
ENST00000653163.1
CHASERR
Exon
SCLC-N


chr15: 96321706
ENST00000502125.6
NR2F2-AS1
Intron
SCLC-N


chr15: 98915596
ENST00000560144.1
IGF1R
Intron
SCLC-N


chr15: 98915756
ENST00000560144.1
IGF1R
Intron
SCLC-N


chr16: 629397
ENST00000573440.1
NA
Exon
SCLC-N


chr16: 629476
ENST00000573440.1
NA
Exon
SCLC-N


chr16: 629563
ENST00000573440.1
NA
Exon
SCLC-N


chr16: 629635
ENST00000573440.1
NA
Exon
SCLC-N


chr16: 629671
ENST00000573440.1
NA
Exon
SCLC-N


chr16: 629785
ENST00000573440.1
NA
Exon
SCLC-N


chr16: 629797
ENST00000573440.1
NA
Exon
SCLC-N


chr16: 1158781
ENST00000638323.1
CACNA1H
Intron
SCLC-N


chr16: 1158792
ENST00000638323.1
CACNA1H
Intron
SCLC-N


chr16: 1158995
ENST00000638323.1
CACNA1H
Intron
SCLC-N


chr16: 2283037
ENST00000569062.1
ABCA3
Intron
SCLC-N


chr16: 2283209
ENST00000569062.1
ABCA3
Exon
SCLC-N


chr16: 11349827
ENST00000649869.1
NA
Intron
SCLC-N


chr16: 11349915
ENST00000649869.1
NA
Intron
SCLC-N


chr16: 11609643
ENST00000574848.5
LITAF
Intron
SCLC-N


chr16: 16067230
ENST00000399408.6
ABCC1
Intron
SCLC-N


chr16: 16067239
ENST00000399408.6
ABCC1
Intron
SCLC-N


chr16: 16067303
ENST00000399408.6
ABCC1
Intron
SCLC-N


chr16: 16067337
ENST00000399408.6
ABCC1
Intron
SCLC-N


chr16: 16067364
ENST00000399408.6
ABCC1
Intron
SCLC-N


chr16: 17972619
ENST00000567304.1
NA
Intron
SCLC-N


chr16: 49491744
ENST00000561648.5
ZNF423
Intron
SCLC-N


chr16: 49499397
ENST00000561648.5
ZNF423
Intron
SCLC-N


chr16: 55324765
ENST00000558730.2
NA
Intron
SCLC-N


chr16: 55324781
ENST00000558730.2
NA
Intron
SCLC-N


chr16: 64947764
ENST00000394156.7
CDH11
Exon
SCLC-N


chr16: 64947795
ENST00000394156.7
CDH11
Exon
SCLC-N


chr16: 64947825
ENST00000394156.7
CDH11
Exon
SCLC-N


chr16: 64950797
ENST00000394156.7
CDH11
Exon
SCLC-N


chr16: 64950806
ENST00000394156.7
CDH11
Exon
SCLC-N


chr16: 69819451
ENST00000359154.6
WWP2
Intron
SCLC-N


chr16: 85287074
ENST00000637419.1
GSE1
Intron
SCLC-N


chr16: 85287098
ENST00000637419.1
GSE1
Intron
SCLC-N


chr16: 85287146
ENST00000637419.1
GSE1
Intron
SCLC-N


chr16: 85287168
ENST00000637419.1
GSE1
Intron
SCLC-N


chr16: 87315250
ENST00000618367.4
C16orf95
Intron
SCLC-N


chr16: 87315257
ENST00000618367.4
C16orf95
Intron
SCLC-N


chr16: 88886878
ENST00000565053.1
LOC101927793
Exon
SCLC-N


chr16: 88886885
ENST00000565053.1
LOC101927793
Exon
SCLC-N


chr16: 88886907
ENST00000565053.1
LOC101927793
Exon
SCLC-N


chr16: 88886921
ENST00000565053.1
LOC101927793
Exon
SCLC-N


chr16: 88886923
ENST00000565053.1
LOC101927793
Exon
SCLC-N


chr16: 88886926
ENST00000565053.1
LOC101927793
Exon
SCLC-N


chr16: 88886927
ENST00000565053.1
LOC101927793
Exon
SCLC-N


chr16: 88886933
ENST00000565053.1
LOC101927793
Exon
SCLC-N


chr17: 7384103
ENST00000577009.1
TNK1
Promoter
SCLC-N


chr17: 7384126
ENST00000577009.1
TNK1
Promoter
SCLC-N


chr17: 7384133
ENST00000577009.1
TNK1
Promoter
SCLC-N


chr17: 7384155
ENST00000577009.1
TNK1
Promoter
SCLC-N


chr17: 9212847
ENST00000173229.7
NTN1
Intron
SCLC-N


chr17: 17814663
ENST00000485080.6
SREBF1
Promoter
SCLC-N


chr17: 17814785
ENST00000385104.1
MIR33B
Promoter
SCLC-N


chr17: 17814792
ENST00000385104.1
MIR33B
Promoter
SCLC-N


chr17: 17814825
ENST00000385104.1
MIR33B
Promoter
SCLC-N


chr17: 17815211
ENST00000478616.1
SREBF1
Promoter
SCLC-N


chr17: 17815297
ENST00000478616.1
SREBF1
Promoter
SCLC-N


chr17: 18992147
ENST00000417251.6
SLC5A10
Intron
SCLC-N


chr17: 21453364
ENST00000654263.1
NA
Intron
SCLC-N


chr17: 32520284
ENST00000318217.10
MYO1D
Intron
SCLC-N


chr17: 37507464
ENST00000617516.5
DUSP14
Intron
SCLC-N


chr17: 37507514
ENST00000617516.5
DUSP14
Intron
SCLC-N


chr17: 37512702
ENST00000614411.1
DUSP14
Exon
SCLC-N


chr17: 37512725
ENST00000614411.1
DUSP14
Exon
SCLC-N


chr17: 37512756
ENST00000614411.1
DUSP14
Exon
SCLC-N


chr17: 37512886
ENST00000614411.1
DUSP14
Exon
SCLC-N


chr17: 37512900
ENST00000614411.1
DUSP14
Exon
SCLC-N


chr17: 37512901
ENST00000614411.1
DUSP14
Exon
SCLC-N


chr17: 37512907
ENST00000614411.1
DUSP14
Exon
SCLC-N


chr17: 48543208
ENST00000504972.3
HOXB-AS1
Promoter
SCLC-N


chr17: 50278974
ENST00000511882.1
TMEM92
Exon
SCLC-N


chr17: 50469322
ENST00000510410.5
ACSF2
Intron
SCLC-N


chr17: 50469335
ENST00000510410.5
ACSF2
Intron
SCLC-N


chr17: 50469412
ENST00000510410.5
ACSF2
Intron
SCLC-N


chr17: 50469415
ENST00000510410.5
ACSF2
Intron
SCLC-N


chr17: 50469437
ENST00000510410.5
ACSF2
Intron
SCLC-N


chr17: 50469491
ENST00000510410.5
ACSF2
Intron
SCLC-N


chr17: 57863248
ENST00000577830.6
CUEDC1
Exon
SCLC-N


chr17: 58863486
ENST00000308249.4
PPM1E
Intron
SCLC-N


chr17: 67652568
ENST00000581322.6
PITPNC1
Intron
SCLC-N


chr17: 67652633
ENST00000581322.6
PITPNC1
Intron
SCLC-N


chr17: 67652635
ENST00000581322.6
PITPNC1
Intron
SCLC-N


chr17: 68450868
ENST00000590353.1
PRKAR1A
Intron
SCLC-N


chr17: 68450875
ENST00000590353.1
PRKAR1A
Intron
SCLC-N


chr17: 68450884
ENST00000590353.1
PRKAR1A
Intron
SCLC-N


chr17: 72122815
ENST00000628742.2
SOX9-AS1
Intron
SCLC-N


chr17: 72122840
ENST00000628742.2
SOX9-AS1
Intron
SCLC-N


chr17: 72122875
ENST00000628742.2
SOX9-AS1
Intron
SCLC-N


chr17: 74341931
ENST00000551294.5
KIF19
Exon
SCLC-N


chr17: 74341937
ENST00000551294.5
KIF19
Exon
SCLC-N


chr17: 78384877
ENST00000589425.5
PGS1
Intron
SCLC-N


chr17: 79465820
ENST00000583458.5
RBFOX3
Intron
SCLC-N


chr17: 79465841
ENST00000583458.5
RBFOX3
Intron
SCLC-N


chr17: 81171168
ENST00000414089.5
PVALEF
Intron
SCLC-N


chr17: 81171184
ENST00000414089.5
PVALEF
Intron
SCLC-N


chr17: 81171304
ENST00000414089.5
PVALEF
Intron
SCLC-N


chr18: 5890423
ENST00000581347.2
TMEM200C
Exon
SCLC-N


chr18: 5890435
ENST00000581347.2
TMEM200C
Exon
SCLC-N


chr18: 5891082
ENST00000581347.2
TMEM200C
Exon
SCLC-N


chr18: 5891091
ENST00000581347.2
TMEM200C
Exon
SCLC-N


chr18: 49799492
ENST00000285093.15
ACAA2
Intron
SCLC-N


chr18: 49799496
ENST00000285093.15
ACAA2
Intron
SCLC-N


chr18: 50721810
ENST00000592595.5
MAPK4
Intron
SCLC-N


chr18: 50721992
ENST00000592595.5
MAPK4
Intron
SCLC-N


chr18: 80040054
ENST00000569722.5
RBFA
Intron
SCLC-N


chr18: 80040058
ENST00000569722.5
RBFA
Intron
SCLC-N


chr19: 427246
ENST00000590170.3
SHC2
Intron
SCLC-N


chr19: 1071308
ENST00000591293.2
ARHGAP45
Intron
SCLC-N


chr19: 1071314
ENST00000591293.2
ARHGAP45
Intron
SCLC-N


chr19: 1071455
ENST00000591293.2
ARHGAP45
Intron
SCLC-N


chr19: 3180037
ENST00000246115.5
S1PR4
Exon
SCLC-N


chr19: 3196028
ENST00000588428.5
NCLN
Intron
SCLC-N


chr19: 3196045
ENST00000588428.5
NCLN
Intron
SCLC-N


chr19: 3196296
ENST00000590671.5
NCLN
Intron
SCLC-N


chr19: 3196350
ENST00000590671.5
NCLN
Intron
SCLC-N


chr19: 3196353
ENST00000590671.5
NCLN
Intron
SCLC-N


chr19: 3196354
ENST00000590671.5
NCLN
Intron
SCLC-N


chr19: 3196369
ENST00000590671.5
NCLN
Intron
SCLC-N


chr19: 3196370
ENST00000590671.5
NCLN
Intron
SCLC-N


chr19: 3196390
ENST00000590671.5
NCLN
Intron
SCLC-N


chr19: 3196394
ENST00000590671.5
NCLN
Intron
SCLC-N


chr19: 3196395
ENST00000590671.5
NCLN
Intron
SCLC-N


chr19: 3196430
ENST00000590671.5
NCLN
Intron
SCLC-N


chr19: 3444440
ENST00000641145.1
NFIC
Intron
SCLC-N


chr19: 5048951
ENST00000611640.4
KDM4B
Intron
SCLC-N


chr19: 6074048
ENST00000589742.5
RFX2
Intron
SCLC-N


chr19: 14434616
ENST00000585619.5
PKN1
Intron
SCLC-N


chr19: 15452847
ENST00000599694.1
RASAL3
Intron
SCLC-N


chr19: 15452855
ENST00000599694.1
RASAL3
Intron
SCLC-N


chr19: 15452871
ENST00000599694.1
RASAL3
Intron
SCLC-N


chr19: 15453399
ENST00000609274.5
RASAL3
Exon
SCLC-N


chr19: 15453406
ENST00000609274.5
RASAL3
Exon
SCLC-N


chr19: 18369135
ENST00000597663.2
PGPEP1
Intron
SCLC-N


chr19: 18489610
ENST00000262809.9
ELL
Intron
SCLC-N


chr19: 18743299
ENST00000321949.13
CRTC1
Intron
SCLC-N


chr19: 18743305
ENST00000321949.13
CRTC1
Intron
SCLC-N


chr19: 18743312
ENST00000321949.13
CRTC1
Intron
SCLC-N


chr19: 18743357
ENST00000321949.13
CRTC1
Intron
SCLC-N


chr19: 18743708
ENST00000321949.13
CRTC1
Intron
SCLC-N


chr19: 18743753
ENST00000321949.13
CRTC1
Intron
SCLC-N


chr19: 18743756
ENST00000321949.13
CRTC1
Intron
SCLC-N


chr19: 18743757
ENST00000321949.13
CRTC1
Intron
SCLC-N


chr19: 18743807
ENST00000321949.13
CRTC1
Intron
SCLC-N


chr19: 18744990
ENST00000321949.13
CRTC1
Intron
SCLC-N


chr19: 18745096
ENST00000321949.13
CRTC1
Intron
SCLC-N


chr19: 18745109
ENST00000321949.13
CRTC1
Intron
SCLC-N


chr19: 18745203
ENST00000321949.13
CRTC1
Intron
SCLC-N


chr19: 32971317
ENST00000305768.10
CEP89
Intron
SCLC-N


chr19: 35033769
ENST00000415950.4
SCN1B
Exon
SCLC-N


chr19: 35033778
ENST00000415950.4
SCN1B
Exon
SCLC-N


chr19: 35033779
ENST00000415950.4
SCN1B
Exon
SCLC-N


chr19: 36111275
ENST00000633214.1
OVOL3
Exon
SCLC-N


chr19: 36111643
ENST00000633214.1
OVOL3
Intron
SCLC-N


chr19: 38252905
ENST00000590510.5
SPINT2
Intron
SCLC-N


chr19: 38253105
ENST00000590510.5
SPINT2
Intron
SCLC-N


chr19: 40692091
ENST00000593724.1
COQ8B
Exon
SCLC-N


chr19: 40692102
ENST00000593724.1
COQ8B
Exon
SCLC-N


chr19: 40692117
ENST00000593724.1
COQ8B
Exon
SCLC-N


chr19: 40807102
ENST00000601627.1
CYP2G1P
Intron
SCLC-N


chr19: 40807147
ENST00000601627.1
CYP2G1P
Intron
SCLC-N


chr19: 49104726
ENST00000544278.2
SNRNP70
Exon
SCLC-N


chr19: 49104729
ENST00000544278.2
SNRNP70
Exon
SCLC-N


chr19: 49432507
ENST00000221485.8
SLC17A7
Intron
SCLC-N


chr19: 49432522
ENST00000221485.8
SLC17A7
Exon
SCLC-N


chr19: 50543096
ENST00000599957.5
LRRC4B
Intron
SCLC-N


chr19: 55359687
ENST00000585734.5
FAM71E2
Exon
SCLC-N


chr2: 1946826
ENST00000650081.1
MYT1L
Intron
SCLC-N


chr2: 1946869
ENST00000650081.1
MYT1L
Intron
SCLC-N


chr2: 1947005
ENST00000650081.1
MYT1L
Intron
SCLC-N


chr2: 7020543
ENST00000467276.5
RNF144A
Exon
SCLC-N


chr2: 9379013
ENST00000315273.4
ASAP2
Exon
SCLC-N


chr2: 9379072
ENST00000315273.4
ASAP2
Intron
SCLC-N


chr2: 10163597
ENST00000381786.7
NA
Intron
SCLC-N


chr2: 10163607
ENST00000381786.7
NA
Intron
SCLC-N


chr2: 10342807
ENST00000423674.5
HPCAL1
Intron
SCLC-N


chr2: 23621054
ENST00000486442.6
KLHL29
Intron
SCLC-N


chr2: 25419491
ENST00000496972.6
DTNB
Intron
SCLC-N


chr2: 25419728
ENST00000496972.6
DTNB
Intron
SCLC-N


chr2: 67561523
ENST00000433065.1
NA
Promoter
SCLC-N


chr2: 72921047
ENST00000394111.6
EMX1
Intron
SCLC-N


chr2: 72921051
ENST00000394111.6
EMX1
Intron
SCLC-N


chr2: 74647996
ENST00000536235.5
M1AP
Intron
SCLC-N


chr2: 74648089
ENST00000536235.5
M1AP
Intron
SCLC-N


chr2: 74648095
ENST00000536235.5
M1AP
Intron
SCLC-N


chr2: 74648101
ENST00000536235.5
M1AP
Intron
SCLC-N


chr2: 74648113
ENST00000536235.5
M1AP
Intron
SCLC-N


chr2: 74648116
ENST00000536235.5
M1AP
Intron
SCLC-N


chr2: 74648129
ENST00000536235.5
M1AP
Intron
SCLC-N


chr2: 74648130
ENST00000536235.5
M1AP
Intron
SCLC-N


chr2: 74648136
ENST00000536235.5
M1AP
Intron
SCLC-N


chr2: 74648141
ENST00000536235.5
M1AP
Intron
SCLC-N


chr2: 74648148
ENST00000536235.5
M1AP
Intron
SCLC-N


chr2: 74648177
ENST00000536235.5
M1AP
Intron
SCLC-N


chr2: 74648178
ENST00000536235.5
M1AP
Intron
SCLC-N


chr2: 74648184
ENST00000536235.5
M1AP
Intron
SCLC-N


chr2: 74648191
ENST00000536235.5
M1AP
Intron
SCLC-N


chr2: 74648207
ENST00000536235.5
M1AP
Intron
SCLC-N


chr2: 74648217
ENST00000536235.5
M1AP
Intron
SCLC-N


chr2: 74648218
ENST00000536235.5
M1AP
Intron
SCLC-N


chr2: 74648227
ENST00000536235.5
M1AP
Intron
SCLC-N


chr2: 74648245
ENST00000536235.5
M1AP
Intron
SCLC-N


chr2: 74648250
ENST00000536235.5
M1AP
Intron
SCLC-N


chr2: 74648260
ENST00000536235.5
M1AP
Intron
SCLC-N


chr2: 74648261
ENST00000536235.5
M1AP
Intron
SCLC-N


chr2: 74648273
ENST00000290536.9
M1AP
Promoter
SCLC-N


chr2: 74648280
ENST00000290536.9
M1AP
Promoter
SCLC-N


chr2: 85243788
ENST00000282111.4
TCF7L1
Intron
SCLC-N


chr2: 109498113
ENST00000309415.8
SH3RF3
Intron
SCLC-N


chr2: 110807569
ENST00000389811.8
ACOXL
Intron
SCLC-N


chr2: 110807672
ENST00000389811.8
ACOXL
Intron
SCLC-N


chr2: 110807894
ENST00000389811.8
ACOXL
Intron
SCLC-N


chr2: 110807930
ENST00000389811.8
ACOXL
Intron
SCLC-N


chr2: 110807936
ENST00000389811.8
ACOXL
Intron
SCLC-N


chr2: 144404074
ENST00000638087.1
ZEB2
Exon
SCLC-N


chr2: 181656540
ENST00000479558.5
CERKL
Intron
SCLC-N


chr2: 181656605
ENST00000479558.5
CERKL
Intron
SCLC-N


chr2: 233060554
ENST00000359570.9
INPP5D
Exon
SCLC-N


chr2: 233060566
ENST00000359570.9
INPP5D
Exon
SCLC-N


chr2: 233060578
ENST00000359570.9
INPP5D
Exon
SCLC-N


chr2: 233060591
ENST00000359570.9
INPP5D
Exon
SCLC-N


chr2: 237509061
ENST00000422695.5
MLPH
Intron
SCLC-N


chr2: 237509070
ENST00000422695.5
MLPH
Intron
SCLC-N


chr20: 11247428
ENST00000444792.1
LOC339593
Intron
SCLC-N


chr20: 20498264
ENST00000202677.12
RALGAPA2
Intron
SCLC-N


chr20: 20498374
ENST00000202677.12
RALGAPA2
Intron
SCLC-N


chr20: 21101285
ENST00000655093.1
LINC00237
Intron
SCLC-N


chr20: 21101299
ENST00000655093.1
LINC00237
Intron
SCLC-N


chr20: 21101362
ENST00000655093.1
LINC00237
Intron
SCLC-N


chr20: 21101370
ENST00000655093.1
LINC00237
Intron
SCLC-N


chr20: 21101484
ENST00000655093.1
LINC00237
Intron
SCLC-N


chr20: 21101554
ENST00000655093.1
LINC00237
Intron
SCLC-N


chr20: 23085065
ENST00000246006.5
CD93
Exon
SCLC-N


chr20: 33675075
ENST00000606690.5
NECAB3
Promoter
SCLC-N


chr20: 33675097
ENST00000606690.5
NECAB3
Promoter
SCLC-N


chr20: 36528428
ENST00000439595.5
DLGAP4-AS1
Intron
SCLC-N


chr20: 36529592
ENST00000439595.5
DLGAP4-AS1
Intron
SCLC-N


chr20: 36852420
ENST00000237536.9
SOGA1
Intron
SCLC-N


chr20: 36852432
ENST00000237536.9
SOGA1
Intron
SCLC-N


chr20: 53592723
ENST00000431687.5
NA
Intron
SCLC-N


chr20: 56629325
ENST00000416606.1
TFAP2C
Promoter
SCLC-N


chr21: 26572915
ENST00000652641.2
CYYR1
Exon
SCLC-N


chr21: 26573110
ENST00000652641.2
CYYR1
Exon
SCLC-N


chr21: 26573118
ENST00000652641.2
CYYR1
Exon
SCLC-N


chr21: 26573124
ENST00000652641.2
CYYR1
Exon
SCLC-N


chr21: 26573132
ENST00000652641.2
CYYR1
Exon
SCLC-N


chr21: 26573134
ENST00000652641.2
CYYR1
Exon
SCLC-N


chr21: 26573168
ENST00000652641.2
CYYR1
Exon
SCLC-N


chr21: 26573169
ENST00000652641.2
CYYR1
Exon
SCLC-N


chr21: 26573204
ENST00000652641.2
CYYR1
Exon
SCLC-N


chr21: 44521445
ENST00000323084.9
TSPEAR
Intron
SCLC-N


chr21: 44646833
ENST00000323084.9
TSPEAR
Intron
SCLC-N


chr22: 23678260
ENST00000651432.1
GUSBP11
Intron
SCLC-N


chr22: 23678347
ENST00000651432.1
GUSBP11
Intron
SCLC-N


chr22: 50603643
ENST00000329492.6
MAPK8IP2
Exon
SCLC-N


chr3: 50365613
ENST00000606589.1
CYB561D2
Intron
SCLC-N


chr3: 50365664
ENST00000606589.1
CYB561D2
Intron
SCLC-N


chr3: 50365696
ENST00000606589.1
CYB561D2
Intron
SCLC-N


chr3: 50365700
ENST00000606589.1
CYB561D2
Intron
SCLC-N


chr3: 50365707
ENST00000606589.1
CYB561D2
Intron
SCLC-N


chr3: 61796965
ENST00000474889.6
PTPRG
Intron
SCLC-N


chr3: 97949951
ENST00000506682.5
RIOX2
Exon
SCLC-N


chr3: 97949984
ENST00000506682.5
RIOX2
Exon
SCLC-N


chr3: 109192259
ENST00000648541.1
LINC00488
Intron
SCLC-N


chr3: 109192266
ENST00000648541.1
LINC00488
Intron
SCLC-N


chr3: 109192267
ENST00000648541.1
LINC00488
Intron
SCLC-N


chr3: 120284769
ENST00000464295.5
GPR156
Intron
SCLC-N


chr3: 183179196
ENST00000328913.7
MCF2L2
Exon
SCLC-N


chr3: 183179370
ENST00000328913.7
MCF2L2
Exon
SCLC-N


chr3: 183179405
ENST00000328913.7
MCF2L2
Exon
SCLC-N


chr3: 183179434
ENST00000328913.7
MCF2L2
Exon
SCLC-N


chr3: 183179443
ENST00000328913.7
MCF2L2
Exon
SCLC-N


chr3: 186099220
ENST00000472868.6
ETV5
Intron
SCLC-N


chr3: 194305594
ENST00000654752.1
LINC00887
Intron
SCLC-N


chr4: 6957533
ENST00000448507.5
TBC1D14
Intron
SCLC-N


chr4: 6969656
ENST00000448507.5
TBC1D14
Intron
SCLC-N


chr4: 6969657
ENST00000448507.5
TBC1D14
Intron
SCLC-N


chr4: 6969701
ENST00000448507.5
TBC1D14
Intron
SCLC-N


chr4: 6969706
ENST00000448507.5
TBC1D14
Intron
SCLC-N


chr4: 10587871
ENST00000226951.11
CLNK
Intron
SCLC-N


chr4: 10587872
ENST00000226951.11
CLNK
Intron
SCLC-N


chr4: 10587881
ENST00000226951.11
CLNK
Intron
SCLC-N


chr4: 10587882
ENST00000226951.11
CLNK
Intron
SCLC-N


chr4: 52751099
ENST00000650700.1
RASL11B
Intron
SCLC-N


chr5: 1857480
ENST00000509455.1
LINC02116
Promoter
SCLC-N


chr5: 66359037
ENST00000663200.1
NA
Intron
SCLC-N


chr5: 93588643
ENST00000327111.8
NR2F1
Intron
SCLC-N


chr5: 93588648
ENST00000327111.8
NR2F1
Intron
SCLC-N


chr5: 141430928
ENST00000517417.2
PCDHGA1
Intron
SCLC-N


chr5: 141430936
ENST00000517417.2
PCDHGA1
Intron
SCLC-N


chr5: 141430938
ENST00000517417.2
PCDHGA1
Intron
SCLC-N


chr5: 141430943
ENST00000517417.2
PCDHGA1
Intron
SCLC-N


chr5: 141492421
ENST00000517417.2
PCDHGA1
Intron
SCLC-N


chr5: 172244750
ENST00000393792.3
UBTD2
Intron
SCLC-N


chr5: 172244889
ENST00000393792.3
UBTD2
Intron
SCLC-N


chr6: 25318583
ENST00000643807.1
CMAHP
Intron
SCLC-N


chr6: 25318616
ENST00000643807.1
CMAHP
Intron
SCLC-N


chr6: 35469210
ENST00000467020.5
RPL10A
Exon
SCLC-N


chr6: 35469377
ENST00000467020.5
RPL10A
Exon
SCLC-N


chr6: 136923394
ENST00000331858.5
SLC35D3
Intron
SCLC-N


chr7: 1933538
ENST00000265854.11
MAD1L1
Intron
SCLC-N


chr7: 1933549
ENST00000265854.11
MAD1L1
Intron
SCLC-N


chr7: 1933588
ENST00000265854.11
MAD1L1
Intron
SCLC-N


chr7: 44151126
ENST00000437084.1
GCK
Intron
SCLC-N


chr7: 44151127
ENST00000437084.1
GCK
Intron
SCLC-N


chr7: 44151142
ENST00000437084.1
GCK
Intron
SCLC-N


chr7: 44151330
ENST00000437084.1
GCK
Intron
SCLC-N


chr7: 66147063
ENST00000435524.2
NA
Intron
SCLC-N


chr7: 129775659
ENST00000362288.1
MIR96
Promoter
SCLC-N


chr7: 149879536
ENST00000464939.1
ATP6V0E2-AS1
Intron
SCLC-N


chr7: 149879711
ENST00000464939.1
ATP6V0E2-AS1
Intron
SCLC-N


chr7: 151115113
ENST00000463381.5
AGAP3
Intron
SCLC-N


chr7: 151115129
ENST00000463381.5
AGAP3
Intron
SCLC-N


chr7: 151143289
ENST00000463381.5
AGAP3
Intron
SCLC-N


chr7: 151143354
ENST00000463381.5
AGAP3
Exon
SCLC-N


chr7: 151143363
ENST00000463381.5
AGAP3
Exon
SCLC-N


chr8: 80301254
ENST00000656157.1
NA
Intron
SCLC-N


chr8: 80301356
ENST00000656157.1
NA
Intron
SCLC-N


chr8: 80301477
ENST00000656157.1
NA
Intron
SCLC-N


chr8: 81631050
ENST00000522318.1
IMPA1P1
Exon
SCLC-N


chr8: 81631185
ENST00000522318.1
IMPA1P1
Promoter
SCLC-N


chr8: 134499786
ENST00000429442.6
ZFAT
Intron
SCLC-N


chr8: 134499855
ENST00000429442.6
ZFAT
Intron
SCLC-N


chr8: 134499859
ENST00000429442.6
ZFAT
Intron
SCLC-N


chr8: 139604536
ENST00000650269.1
KCNK9
Intron
SCLC-N


chr8: 139604670
ENST00000650269.1
KCNK9
Intron
SCLC-N


chr9: 93299636
ENST00000411624.5
WNK2
Intron
SCLC-N


chr9: 93299661
ENST00000411624.5
WNK2
Intron
SCLC-N


chr9: 93299673
ENST00000411624.5
WNK2
Intron
SCLC-N


chr9: 93299688
ENST00000411624.5
WNK2
Intron
SCLC-N


chr9: 113901537
ENST00000374126.9
ZNF618
Intron
SCLC-N


chr9: 113901541
ENST00000374126.9
ZNF618
Intron
SCLC-N


chr9: 113901566
ENST00000374126.9
ZNF618
Intron
SCLC-N


chr9: 114347778
ENST00000307564.8
AKNA
Exon
SCLC-N


chr9: 114347782
ENST00000307564.8
AKNA
Exon
SCLC-N


chr9: 114347787
ENST00000307564.8
AKNA
Exon
SCLC-N


chr9: 114347808
ENST00000307564.8
AKNA
Exon
SCLC-N


chr9: 114347813
ENST00000307564.8
AKNA
Exon
SCLC-N


chr9: 114347860
ENST00000307564.8
AKNA
Exon
SCLC-N


chr9: 114347866
ENST00000307564.8
AKNA
Exon
SCLC-N


chr9: 123401183
ENST00000373624.6
DENND1A
Intron
SCLC-N


chr9: 123401332
ENST00000373624.6
DENND1A
Intron
SCLC-N


chr9: 136534050
ENST00000651671.1
NOTCH1
Intron
SCLC-N


chr9: 136534055
ENST00000651671.1
NOTCH1
Intron
SCLC-N


chr9: 136534065
ENST00000651671.1
NOTCH1
Intron
SCLC-N


chr9: 136534074
ENST00000651671.1
NOTCH1
Intron
SCLC-N


chr9: 137877774
ENST00000371390.1
LOC100133077
Intron
SCLC-N


chr9: 137877776
ENST00000371390.1
LOC100133077
Intron
SCLC-N


chr9: 137877791
ENST00000371390.1
LOC100133077
Intron
SCLC-N


chr9: 137877794
ENST00000371390.1
LOC100133077
Intron
SCLC-N


chr9: 137877797
ENST00000371390.1
LOC100133077
Intron
SCLC-N


chr9: 137877803
ENST00000371390.1
LOC100133077
Intron
SCLC-N


chr9: 137877815
ENST00000371390.1
LOC100133077
Intron
SCLC-N
















TABLE 22







Additional methylation sites associated with the SCLC-P subtype











Methylation Site
Transcript_ID
Gene_Symbol
Gene_Region
Subtype





chr1: 958193
ENST00000477976.5
NOC2L
Exon
SCLC-P


chr1: 958206
ENST00000477976.5
NOC2L
Exon
SCLC-P


chr1: 958225
ENST00000477976.5
NOC2L
Exon
SCLC-P


chr1: 958355
ENST00000477976.5
NOC2L
Exon
SCLC-P


chr1: 958377
ENST00000477976.5
NOC2L
Exon
SCLC-P


chr1: 958407
ENST00000477976.5
NOC2L
Exon
SCLC-P


chr1: 972487
ENST00000379410.8
PLEKHN1
Intron
SCLC-P


chr1: 972499
ENST00000379410.8
PLEKHN1
Intron
SCLC-P


chr1: 972500
ENST00000379410.8
PLEKHN1
Intron
SCLC-P


chr1: 972536
ENST00000379410.8
PLEKHN1
Intron
SCLC-P


chr1: 972537
ENST00000379410.8
PLEKHN1
Intron
SCLC-P


chr1: 972563
ENST00000379410.8
PLEKHN1
Intron
SCLC-P


chr1: 972564
ENST00000379410.8
PLEKHN1
Intron
SCLC-P


chr1: 972578
ENST00000379410.8
PLEKHN1
Intron
SCLC-P


chr1: 1049344
ENST00000379370.7
AGRN
Exon
SCLC-P


chr1: 1049569
ENST00000379370.7
AGRN
Exon
SCLC-P


chr1: 1049585
ENST00000379370.7
AGRN
Exon
SCLC-P


chr1: 1060899
ENST00000427998.5
LOC100288175
Intron
SCLC-P


chr1: 1060915
ENST00000427998.5
LOC100288175
Intron
SCLC-P


chr1: 1060917
ENST00000427998.5
LOC100288175
Intron
SCLC-P


chr1: 1061051
ENST00000427998.5
LOC100288175
Intron
SCLC-P


chr1: 1061052
ENST00000427998.5
LOC100288175
Intron
SCLC-P


chr1: 1061060
ENST00000427998.5
LOC100288175
Intron
SCLC-P


chr1: 1067284
ENST00000412397.2
LOC100288175
Intron
SCLC-P


chr1: 1073300
ENST00000453464.3
RNF223
Intron
SCLC-P


chr1: 1073322
ENST00000453464.3
RNF223
Intron
SCLC-P


chr1: 1110693
ENST00000379325.7
C1orf159
Intron
SCLC-P


chr1: 1110698
ENST00000379325.7
C1orf159
Intron
SCLC-P


chr1: 1110739
ENST00000379325.7
C1orf159
Intron
SCLC-P


chr1: 1114609
ENST00000379325.7
C1orf159
Intron
SCLC-P


chr1: 1114751
ENST00000379325.7
C1orf159
Intron
SCLC-P


chr1: 1114755
ENST00000379325.7
C1orf159
Intron
SCLC-P


chr1: 1217039
ENST00000360001.11
SDF4
Exon
SCLC-P


chr1: 1217078
ENST00000360001.11
SDF4
Exon
SCLC-P


chr1: 1217143
ENST00000360001.11
SDF4
Exon
SCLC-P


chr1: 1217144
ENST00000360001.11
SDF4
Exon
SCLC-P


chr1: 1217148
ENST00000360001.11
SDF4
Exon
SCLC-P


chr1: 1217149
ENST00000360001.11
SDF4
Exon
SCLC-P


chr1: 1217151
ENST00000360001.11
SDF4
Exon
SCLC-P


chr1: 1217152
ENST00000360001.11
SDF4
Exon
SCLC-P


chr1: 1217168
ENST00000360001.11
SDF4
Exon
SCLC-P


chr1: 1217186
ENST00000360001.11
SDF4
Exon
SCLC-P


chr1: 1217187
ENST00000360001.11
SDF4
Exon
SCLC-P


chr1: 1217188
ENST00000360001.11
SDF4
Exon
SCLC-P


chr1: 1217194
ENST00000360001.11
SDF4
Exon
SCLC-P


chr1: 1217200
ENST00000360001.11
SDF4
Exon
SCLC-P


chr1: 1217201
ENST00000360001.11
SDF4
Exon
SCLC-P


chr1: 1217206
ENST00000360001.11
SDF4
Exon
SCLC-P


chr1: 1217207
ENST00000360001.11
SDF4
Exon
SCLC-P


chr1: 1217223
ENST00000360001.11
SDF4
Exon
SCLC-P


chr1: 1217231
ENST00000360001.11
SDF4
Exon
SCLC-P


chr1: 1217254
ENST00000360001.11
SDF4
Exon
SCLC-P


chr1: 1217260
ENST00000360001.11
SDF4
Exon
SCLC-P


chr1: 1217284
ENST00000360001.11
SDF4
Exon
SCLC-P


chr1: 1217285
ENST00000360001.11
SDF4
Exon
SCLC-P


chr1: 1217287
ENST00000360001.11
SDF4
Exon
SCLC-P


chr1: 1217305
ENST00000360001.11
SDF4
Exon
SCLC-P


chr1: 1217313
ENST00000360001.11
SDF4
Exon
SCLC-P


chr1: 1217317
ENST00000360001.11
SDF4
Exon
SCLC-P


chr1: 1217318
ENST00000360001.11
SDF4
Exon
SCLC-P


chr1: 1217319
ENST00000360001.11
SDF4
Exon
SCLC-P


chr1: 1217339
ENST00000360001.11
SDF4
Exon
SCLC-P


chr1: 1223730
ENST00000360001.11
SDF4
Intron
SCLC-P


chr1: 1224575
ENST00000360001.11
SDF4
Intron
SCLC-P


chr1: 1232875
ENST00000459994.2
SDF4
Promoter
SCLC-P


chr1: 1232876
ENST00000459994.2
SDF4
Promoter
SCLC-P


chr1: 1232881
ENST00000459994.2
SDF4
Promoter
SCLC-P


chr1: 1232882
ENST00000459994.2
SDF4
Promoter
SCLC-P


chr1: 1232896
ENST00000459994.2
SDF4
Promoter
SCLC-P


chr1: 1232897
ENST00000459994.2
SDF4
Promoter
SCLC-P


chr1: 1232914
ENST00000459994.2
SDF4
Promoter
SCLC-P


chr1: 1232915
ENST00000459994.2
SDF4
Promoter
SCLC-P


chr1: 1232916
ENST00000459994.2
SDF4
Promoter
SCLC-P


chr1: 1232917
ENST00000459994.2
SDF4
Promoter
SCLC-P


chr1: 1232923
ENST00000459994.2
SDF4
Promoter
SCLC-P


chr1: 1232924
ENST00000459994.2
SDF4
Promoter
SCLC-P


chr1: 1232926
ENST00000459994.2
SDF4
Promoter
SCLC-P


chr1: 1232927
ENST00000459994.2
SDF4
Promoter
SCLC-P


chr1: 1232932
ENST00000459994.2
SDF4
Promoter
SCLC-P


chr1: 1232944
ENST00000459994.2
SDF4
Promoter
SCLC-P


chr1: 1232945
ENST00000459994.2
SDF4
Promoter
SCLC-P


chr1: 1232963
ENST00000459994.2
SDF4
Promoter
SCLC-P


chr1: 1232964
ENST00000459994.2
SDF4
Promoter
SCLC-P


chr1: 1232972
ENST00000360001.11
SDF4
Promoter
SCLC-P


chr1: 1232973
ENST00000360001.11
SDF4
Promoter
SCLC-P


chr1: 1232974
ENST00000360001.11
SDF4
Promoter
SCLC-P


chr1: 1232975
ENST00000360001.11
SDF4
Promoter
SCLC-P


chr1: 1232984
ENST00000360001.11
SDF4
Promoter
SCLC-P


chr1: 1232985
ENST00000360001.11
SDF4
Promoter
SCLC-P


chr1: 1232986
ENST00000360001.11
SDF4
Promoter
SCLC-P


chr1: 1232987
ENST00000360001.11
SDF4
Promoter
SCLC-P


chr1: 1232998
ENST00000360001.11
SDF4
Promoter
SCLC-P


chr1: 1232999
ENST00000360001.11
SDF4
Promoter
SCLC-P


chr1: 1233016
ENST00000263741.12
SDF4
Promoter
SCLC-P


chr1: 1233017
ENST00000263741.12
SDF4
Promoter
SCLC-P


chr1: 1233031
ENST00000263741.12
SDF4
Promoter
SCLC-P


chr1: 1233077
ENST00000379198.5
B3GALT6
Exon
SCLC-P


chr1: 1233149
ENST00000379198.5
B3GALT6
Exon
SCLC-P


chr1: 1233151
ENST00000379198.5
B3GALT6
Exon
SCLC-P


chr1: 1233154
ENST00000379198.5
B3GALT6
Exon
SCLC-P


chr1: 1233160
ENST00000379198.5
B3GALT6
Exon
SCLC-P


chr1: 1233162
ENST00000379198.5
B3GALT6
Exon
SCLC-P


chr1: 1233164
ENST00000379198.5
B3GALT6
Exon
SCLC-P


chr1: 1233198
ENST00000379198.5
B3GALT6
Exon
SCLC-P


chr1: 1233209
ENST00000379198.5
B3GALT6
Exon
SCLC-P


chr1: 1233224
ENST00000379198.5
B3GALT6
Exon
SCLC-P


chr1: 1233226
ENST00000379198.5
B3GALT6
Exon
SCLC-P


chr1: 1233229
ENST00000379198.5
B3GALT6
Exon
SCLC-P


chr1: 1233272
ENST00000379198.5
B3GALT6
Exon
SCLC-P


chr1: 1233275
ENST00000379198.5
B3GALT6
Exon
SCLC-P


chr1: 1233277
ENST00000379198.5
B3GALT6
Exon
SCLC-P


chr1: 1233282
ENST00000379198.5
B3GALT6
Exon
SCLC-P


chr1: 1295076
ENST00000492936.5
ACAP3
Intron
SCLC-P


chr1: 1295077
ENST00000492936.5
ACAP3
Intron
SCLC-P


chr1: 1295086
ENST00000492936.5
ACAP3
Intron
SCLC-P


chr1: 1347350
ENST00000378891.9
DVL1
Intron
SCLC-P


chr1: 1347360
ENST00000378891.9
DVL1
Intron
SCLC-P


chr1: 1374140
ENST00000338370.7
AURKAIP1
Exon
SCLC-P


chr1: 1387723
ENST00000480479.5
CCNL2
Intron
SCLC-P


chr1: 1387741
ENST00000480479.5
CCNL2
Intron
SCLC-P


chr1: 1396740
ENST00000400809.8
CCNL2
Intron
SCLC-P


chr1: 1396771
ENST00000400809.8
CCNL2
Intron
SCLC-P


chr1: 1475192
ENST00000673477.1
ATAD3B
Intron
SCLC-P


chr1: 1475215
ENST00000673477.1
ATAD3B
Intron
SCLC-P


chr1: 1475335
ENST00000673477.1
ATAD3B
Intron
SCLC-P


chr1: 1475416
ENST00000673477.1
ATAD3B
Intron
SCLC-P


chr1: 1475435
ENST00000673477.1
ATAD3B
Intron
SCLC-P


chr1: 1475454
ENST00000673477.1
ATAD3B
Intron
SCLC-P


chr1: 1475460
ENST00000673477.1
ATAD3B
Intron
SCLC-P


chr1: 1475463
ENST00000673477.1
ATAD3B
Intron
SCLC-P


chr1: 1475470
ENST00000673477.1
ATAD3B
Intron
SCLC-P


chr1: 1475563
ENST00000673477.1
ATAD3B
Intron
SCLC-P


chr1: 1534445
ENST00000378756.8
ATAD3A
Exon
SCLC-P


chr1: 1547615
ENST00000291386.4
SSU72
Intron
SCLC-P


chr1: 1549249
ENST00000291386.4
SSU72
Intron
SCLC-P


chr1: 1549250
ENST00000291386.4
SSU72
Intron
SCLC-P


chr1: 1549259
ENST00000291386.4
SSU72
Intron
SCLC-P


chr1: 1549281
ENST00000291386.4
SSU72
Intron
SCLC-P


chr1: 1549282
ENST00000291386.4
SSU72
Intron
SCLC-P


chr1: 1549287
ENST00000291386.4
SSU72
Intron
SCLC-P


chr1: 1549288
ENST00000291386.4
SSU72
Intron
SCLC-P


chr1: 1549318
ENST00000291386.4
SSU72
Intron
SCLC-P


chr1: 1550663
ENST00000291386.4
SSU72
Intron
SCLC-P


chr1: 1554593
ENST00000291386.4
SSU72
Intron
SCLC-P


chr1: 1561606
ENST00000291386.4
SSU72
Intron
SCLC-P


chr1: 1624522
ENST00000467597.1
MIB2
Promoter
SCLC-P


chr1: 1624565
ENST00000467597.1
MIB2
Promoter
SCLC-P


chr1: 1624573
ENST00000467597.1
MIB2
Promoter
SCLC-P


chr1: 1624618
ENST00000467597.1
MIB2
Promoter
SCLC-P


chr1: 1624646
ENST00000467597.1
MIB2
Promoter
SCLC-P


chr1: 1683375
ENST00000611123.1
SLC35E2B
Intron
SCLC-P


chr1: 1765128
ENST00000341426.9
NADK
Intron
SCLC-P


chr1: 1765131
ENST00000341426.9
NADK
Intron
SCLC-P


chr1: 1874342
ENST00000610897.4
GNB1
Intron
SCLC-P


chr1: 1874344
ENST00000610897.4
GNB1
Intron
SCLC-P


chr1: 1923286
ENST00000642590.1
CFAP74
Intron
SCLC-P


chr1: 1923287
ENST00000642590.1
CFAP74
Intron
SCLC-P


chr1: 1923297
ENST00000642590.1
CFAP74
Intron
SCLC-P


chr1: 1923895
ENST00000642590.1
CFAP74
Exon
SCLC-P


chr1: 1923913
ENST00000642590.1
CFAP74
Exon
SCLC-P


chr1: 2187492
ENST00000400919.7
FAAP20
Intron
SCLC-P


chr1: 2187583
ENST00000400919.7
FAAP20
Intron
SCLC-P


chr1: 2187584
ENST00000400919.7
FAAP20
Intron
SCLC-P


chr1: 2187593
ENST00000400919.7
FAAP20
Intron
SCLC-P


chr1: 2187594
ENST00000400919.7
FAAP20
Intron
SCLC-P


chr1: 2187595
ENST00000400919.7
FAAP20
Intron
SCLC-P


chr1: 2187596
ENST00000400919.7
FAAP20
Intron
SCLC-P


chr1: 2187600
ENST00000400919.7
FAAP20
Intron
SCLC-P


chr1: 2234472
ENST00000378536.5
SKI
Intron
SCLC-P


chr1: 2234498
ENST00000378536.5
SKI
Intron
SCLC-P


chr1: 2317877
ENST00000661319.1
NA
Intron
SCLC-P


chr1: 2317882
ENST00000661319.1
NA
Intron
SCLC-P


chr1: 2317884
ENST00000661319.1
NA
Intron
SCLC-P


chr1: 2324486
ENST00000378531.8
MORN1
Intron
SCLC-P


chr1: 2426444
ENST00000609981.5
PLCH2
Intron
SCLC-P


chr1: 2427172
ENST00000609981.5
PLCH2
Intron
SCLC-P


chr1: 2427361
ENST00000609981.5
PLCH2
Intron
SCLC-P


chr1: 2427381
ENST00000609981.5
PLCH2
Intron
SCLC-P


chr1: 2502417
ENST00000473964.5
PLCH2
Exon
SCLC-P


chr1: 2502425
ENST00000473964.5
PLCH2
Exon
SCLC-P


chr1: 2502426
ENST00000473964.5
PLCH2
Exon
SCLC-P


chr1: 2502454
ENST00000473964.5
PLCH2
Exon
SCLC-P


chr1: 2502455
ENST00000473964.5
PLCH2
Exon
SCLC-P


chr1: 2502463
ENST00000473964.5
PLCH2
Exon
SCLC-P


chr1: 3087392
ENST00000511072.5
PRDM16
Intron
SCLC-P


chr1: 3160979
ENST00000511072.5
PRDM16
Intron
SCLC-P


chr1: 3173943
ENST00000511072.5
PRDM16
Intron
SCLC-P


chr1: 3173971
ENST00000511072.5
PRDM16
Intron
SCLC-P


chr1: 3198355
ENST00000511072.5
PRDM16
Intron
SCLC-P


chr1: 3216544
ENST00000511072.5
PRDM16
Intron
SCLC-P


chr1: 3216547
ENST00000511072.5
PRDM16
Intron
SCLC-P


chr1: 3331596
ENST00000378391.6
PRDM16
Intron
SCLC-P


chr1: 3331806
ENST00000378391.6
PRDM16
Intron
SCLC-P


chr1: 3357671
ENST00000378391.6
PRDM16
Intron
SCLC-P


chr1: 3357683
ENST00000378391.6
PRDM16
Intron
SCLC-P


chr1: 3357686
ENST00000378391.6
PRDM16
Intron
SCLC-P


chr1: 3357687
ENST00000378391.6
PRDM16
Intron
SCLC-P


chr1: 3358718
ENST00000378391.6
PRDM16
Intron
SCLC-P


chr1: 3364529
ENST00000378391.6
PRDM16
Intron
SCLC-P


chr1: 3364709
ENST00000378391.6
PRDM16
Intron
SCLC-P


chr1: 3364710
ENST00000378391.6
PRDM16
Intron
SCLC-P


chr1: 3366242
ENST00000378391.6
PRDM16
Intron
SCLC-P


chr1: 3366257
ENST00000378391.6
PRDM16
Intron
SCLC-P


chr1: 3366414
ENST00000378391.6
PRDM16
Intron
SCLC-P


chr1: 3366416
ENST00000378391.6
PRDM16
Intron
SCLC-P


chr1: 3367039
ENST00000378391.6
PRDM16
Intron
SCLC-P


chr1: 3378512
ENST00000378391.6
PRDM16
Intron
SCLC-P


chr1: 3390787
ENST00000511072.5
PRDM16
Intron
SCLC-P


chr1: 3391958
ENST00000511072.5
PRDM16
Intron
SCLC-P


chr1: 3397625
ENST00000511072.5
PRDM16
Intron
SCLC-P


chr1: 3397643
ENST00000511072.5
PRDM16
Intron
SCLC-P


chr1: 3405173
ENST00000511072.5
PRDM16
Intron
SCLC-P


chr1: 3405197
ENST00000511072.5
PRDM16
Intron
SCLC-P


chr1: 3405203
ENST00000511072.5
PRDM16
Intron
SCLC-P


chr1: 3405232
ENST00000511072.5
PRDM16
Intron
SCLC-P


chr1: 3405254
ENST00000511072.5
PRDM16
Intron
SCLC-P


chr1: 3405293
ENST00000511072.5
PRDM16
Intron
SCLC-P


chr1: 3405451
ENST00000511072.5
PRDM16
Intron
SCLC-P


chr1: 3405485
ENST00000511072.5
PRDM16
Intron
SCLC-P


chr1: 3405689
ENST00000511072.5
PRDM16
Intron
SCLC-P


chr1: 3405691
ENST00000511072.5
PRDM16
Intron
SCLC-P


chr1: 3405702
ENST00000511072.5
PRDM16
Intron
SCLC-P


chr1: 3405802
ENST00000511072.5
PRDM16
Intron
SCLC-P


chr1: 3405818
ENST00000511072.5
PRDM16
Intron
SCLC-P


chr1: 3407090
ENST00000511072.5
PRDM16
Intron
SCLC-P


chr1: 3423062
ENST00000511072.5
PRDM16
Intron
SCLC-P


chr1: 3425598
ENST00000606170.1
PRDM16
Exon
SCLC-P


chr1: 3497141
ENST00000491842.1
MEGF6
Promoter
SCLC-P


chr1: 3497522
ENST00000491842.1
MEGF6
Promoter
SCLC-P


chr1: 3497894
ENST00000356575.9
MEGF6
Intron
SCLC-P


chr1: 3539515
ENST00000356575.9
MEGF6
Intron
SCLC-P


chr1: 3539564
ENST00000356575.9
MEGF6
Intron
SCLC-P


chr1: 3539694
ENST00000356575.9
MEGF6
Intron
SCLC-P


chr1: 3539695
ENST00000356575.9
MEGF6
Intron
SCLC-P


chr1: 3539827
ENST00000356575.9
MEGF6
Intron
SCLC-P


chr1: 3541769
ENST00000356575.9
MEGF6
Intron
SCLC-P


chr1: 3541929
ENST00000356575.9
MEGF6
Intron
SCLC-P


chr1: 3541930
ENST00000356575.9
MEGF6
Intron
SCLC-P


chr1: 3541945
ENST00000356575.9
MEGF6
Intron
SCLC-P


chr1: 3541946
ENST00000356575.9
MEGF6
Intron
SCLC-P


chr1: 3552587
ENST00000356575.9
MEGF6
Intron
SCLC-P


chr1: 3552608
ENST00000356575.9
MEGF6
Intron
SCLC-P


chr1: 3552609
ENST00000356575.9
MEGF6
Intron
SCLC-P


chr1: 3552611
ENST00000356575.9
MEGF6
Intron
SCLC-P


chr1: 3552612
ENST00000356575.9
MEGF6
Intron
SCLC-P


chr1: 3556936
ENST00000356575.9
MEGF6
Intron
SCLC-P


chr1: 3567665
ENST00000356575.9
MEGF6
Intron
SCLC-P


chr1: 3579918
ENST00000485002.6
MEGF6
Intron
SCLC-P


chr1: 3579933
ENST00000485002.6
MEGF6
Intron
SCLC-P


chr1: 3581124
ENST00000485002.6
MEGF6
Intron
SCLC-P


chr1: 3581129
ENST00000485002.6
MEGF6
Intron
SCLC-P


chr1: 3589350
ENST00000485002.6
MEGF6
Intron
SCLC-P


chr1: 3589366
ENST00000485002.6
MEGF6
Intron
SCLC-P


chr1: 3589367
ENST00000485002.6
MEGF6
Intron
SCLC-P


chr1: 3589380
ENST00000485002.6
MEGF6
Intron
SCLC-P


chr1: 3589381
ENST00000485002.6
MEGF6
Intron
SCLC-P


chr1: 3589384
ENST00000485002.6
MEGF6
Intron
SCLC-P


chr1: 3589385
ENST00000485002.6
MEGF6
Intron
SCLC-P


chr1: 3591983
ENST00000485002.6
MEGF6
Intron
SCLC-P


chr1: 3591990
ENST00000485002.6
MEGF6
Intron
SCLC-P


chr1: 3591997
ENST00000485002.6
MEGF6
Intron
SCLC-P


chr1: 3592007
ENST00000485002.6
MEGF6
Intron
SCLC-P


chr1: 3595668
ENST00000356575.9
MEGF6
Intron
SCLC-P


chr1: 3595680
ENST00000356575.9
MEGF6
Intron
SCLC-P


chr1: 3595696
ENST00000356575.9
MEGF6
Intron
SCLC-P


chr1: 3602483
ENST00000356575.9
MEGF6
Exon
SCLC-P


chr1: 3602519
ENST00000356575.9
MEGF6
Exon
SCLC-P


chr1: 3602525
ENST00000356575.9
MEGF6
Exon
SCLC-P


chr1: 3602545
ENST00000356575.9
MEGF6
Exon
SCLC-P


chr1: 3602549
ENST00000356575.9
MEGF6
Exon
SCLC-P


chr1: 3602556
ENST00000356575.9
MEGF6
Exon
SCLC-P


chr1: 3602559
ENST00000356575.9
MEGF6
Exon
SCLC-P


chr1: 3605977
ENST00000356575.9
MEGF6
Intron
SCLC-P


chr1: 3606636
ENST00000356575.9
MEGF6
Intron
SCLC-P


chr1: 3673669
ENST00000378295.9
TP73
Intron
SCLC-P


chr1: 3673674
ENST00000378295.9
TP73
Intron
SCLC-P


chr1: 3673802
ENST00000378295.9
TP73
Intron
SCLC-P


chr1: 3679014
ENST00000378295.9
TP73
Intron
SCLC-P


chr1: 3679030
ENST00000378295.9
TP73
Intron
SCLC-P


chr1: 3679034
ENST00000378295.9
TP73
Intron
SCLC-P


chr1: 3682353
ENST00000603362.5
TP73
Promoter
SCLC-P


chr1: 3682356
ENST00000603362.5
TP73
Promoter
SCLC-P


chr1: 3682380
ENST00000378295.9
TP73
Exon
SCLC-P


chr1: 3683938
ENST00000378295.9
TP73
Intron
SCLC-P


chr1: 3684046
ENST00000378295.9
TP73
Intron
SCLC-P


chr1: 3684085
ENST00000378295.9
TP73
Intron
SCLC-P


chr1: 3701698
ENST00000378295.9
TP73
Intron
SCLC-P


chr1: 3704685
ENST00000378295.9
TP73
Intron
SCLC-P


chr1: 3704725
ENST00000378295.9
TP73
Intron
SCLC-P


chr1: 3704744
ENST00000378295.9
TP73
Intron
SCLC-P


chr1: 3704745
ENST00000378295.9
TP73
Intron
SCLC-P


chr1: 3704882
ENST00000378295.9
TP73
Intron
SCLC-P


chr1: 3705781
ENST00000378295.9
TP73
Intron
SCLC-P


chr1: 3705782
ENST00000378295.9
TP73
Intron
SCLC-P


chr1: 3705842
ENST00000378295.9
TP73
Intron
SCLC-P


chr1: 3705849
ENST00000378295.9
TP73
Intron
SCLC-P


chr1: 3705997
ENST00000378295.9
TP73
Intron
SCLC-P


chr1: 3706755
ENST00000378295.9
TP73
Intron
SCLC-P


chr1: 3706769
ENST00000378295.9
TP73
Intron
SCLC-P


chr1: 3706775
ENST00000378295.9
TP73
Intron
SCLC-P


chr1: 3706905
ENST00000378295.9
TP73
Intron
SCLC-P


chr1: 3706906
ENST00000378295.9
TP73
Intron
SCLC-P


chr1: 3706912
ENST00000378295.9
TP73
Intron
SCLC-P


chr1: 3706913
ENST00000378295.9
TP73
Intron
SCLC-P


chr1: 3706926
ENST00000378295.9
TP73
Intron
SCLC-P


chr1: 3706937
ENST00000378295.9
TP73
Intron
SCLC-P


chr1: 3707095
ENST00000378295.9
TP73
Intron
SCLC-P


chr1: 3707423
ENST00000378295.9
TP73
Intron
SCLC-P


chr1: 3722142
ENST00000378295.9
TP73
Exon
SCLC-P


chr1: 3727277
ENST00000604566.1
TP73
Promoter
SCLC-P


chr1: 3733380
ENST00000378295.9
TP73
Exon
SCLC-P


chr1: 3733407
ENST00000378295.9
TP73
Exon
SCLC-P


chr1: 3733595
ENST00000378295.9
TP73
Exon
SCLC-P


chr1: 3733604
ENST00000378295.9
TP73
Exon
SCLC-P


chr1: 3734365
ENST00000378295.9
TP73
Exon
SCLC-P


chr1: 3752708
ENST00000462521.2
CCDC27
Exon
SCLC-P


chr1: 3752716
ENST00000462521.2
CCDC27
Exon
SCLC-P


chr1: 3752735
ENST00000462521.2
CCDC27
Exon
SCLC-P


chr1: 3752783
ENST00000462521.2
CCDC27
Exon
SCLC-P


chr1: 3763125
ENST00000462521.2
CCDC27
Exon
SCLC-P


chr1: 3763130
ENST00000462521.2
CCDC27
Exon
SCLC-P


chr1: 3763131
ENST00000462521.2
CCDC27
Exon
SCLC-P


chr1: 3912101
ENST00000667408.1
LINC01134
Intron
SCLC-P


chr1: 5651349
ENST00000637702.1
NA
Intron
SCLC-P


chr1: 6019912
ENST00000655548.1
KCNAB2
Intron
SCLC-P


chr1: 6019918
ENST00000655548.1
KCNAB2
Intron
SCLC-P


chr1: 6047242
ENST00000389632.9
KCNAB2
Intron
SCLC-P


chr1: 6048447
ENST00000389632.9
KCNAB2
Intron
SCLC-P


chr1: 6056292
ENST00000389632.9
KCNAB2
Intron
SCLC-P


chr1: 6056296
ENST00000389632.9
KCNAB2
Intron
SCLC-P


chr1: 6056297
ENST00000389632.9
KCNAB2
Intron
SCLC-P


chr1: 6056324
ENST00000389632.9
KCNAB2
Intron
SCLC-P


chr1: 6056335
ENST00000389632.9
KCNAB2
Intron
SCLC-P


chr1: 6056336
ENST00000389632.9
KCNAB2
Intron
SCLC-P


chr1: 6056337
ENST00000389632.9
KCNAB2
Intron
SCLC-P


chr1: 6056340
ENST00000389632.9
KCNAB2
Intron
SCLC-P


chr1: 6056341
ENST00000389632.9
KCNAB2
Intron
SCLC-P


chr1: 6059746
ENST00000389632.9
KCNAB2
Intron
SCLC-P


chr1: 6087287
ENST00000655548.1
KCNAB2
Intron
SCLC-P


chr1: 6087288
ENST00000655548.1
KCNAB2
Intron
SCLC-P


chr1: 6087294
ENST00000655548.1
KCNAB2
Intron
SCLC-P


chr1: 6087295
ENST00000655548.1
KCNAB2
Intron
SCLC-P


chr1: 6089479
ENST00000655548.1
KCNAB2
Intron
SCLC-P


chr1: 6090587
ENST00000378097.6
KCNAB2
Intron
SCLC-P


chr1: 6090600
ENST00000378097.6
KCNAB2
Intron
SCLC-P


chr1: 6095342
ENST00000652911.1
KCNAB2
Exon
SCLC-P


chr1: 6100315
ENST00000662815.1
KCNAB2
Exon
SCLC-P


chr1: 6106506
ENST00000475121.1
CHD5
Intron
SCLC-P


chr1: 6106674
ENST00000262450.8
CHD5
Exon
SCLC-P


chr1: 6125548
ENST00000496404.1
CHD5
Intron
SCLC-P


chr1: 6125555
ENST00000496404.1
CHD5
Intron
SCLC-P


chr1: 6125595
ENST00000496404.1
CHD5
Intron
SCLC-P


chr1: 6125777
ENST00000496404.1
CHD5
Intron
SCLC-P


chr1: 6128791
ENST00000496404.1
CHD5
Intron
SCLC-P


chr1: 6128814
ENST00000496404.1
CHD5
Intron
SCLC-P


chr1: 6135308
ENST00000262450.8
CHD5
Exon
SCLC-P


chr1: 6135322
ENST00000262450.8
CHD5
Exon
SCLC-P


chr1: 6136178
ENST00000262450.8
CHD5
Intron
SCLC-P


chr1: 6145994
ENST00000262450.8
CHD5
Intron
SCLC-P


chr1: 6146008
ENST00000262450.8
CHD5
Intron
SCLC-P


chr1: 6146131
ENST00000262450.8
CHD5
Intron
SCLC-P


chr1: 6146789
ENST00000262450.8
CHD5
Exon
SCLC-P


chr1: 6161927
ENST00000262450.8
CHD5
Intron
SCLC-P


chr1: 6161939
ENST00000262450.8
CHD5
Intron
SCLC-P


chr1: 6161959
ENST00000262450.8
CHD5
Intron
SCLC-P


chr1: 6165907
ENST00000262450.8
CHD5
Intron
SCLC-P


chr1: 6210726
ENST00000463453.1
RNF207
Promoter
SCLC-P


chr1: 6211967
ENST00000483336.1
RNF207
Promoter
SCLC-P


chr1: 6222880
ENST00000343813.10
ICMT
Exon
SCLC-P


chr1: 6236574
ENST00000650463.1
LINC00337
Intron
SCLC-P


chr1: 6236582
ENST00000650463.1
LINC00337
Intron
SCLC-P


chr1: 6236585
ENST00000650463.1
LINC00337
Intron
SCLC-P


chr1: 6236593
ENST00000650463.1
LINC00337
Intron
SCLC-P


chr1: 6236596
ENST00000650463.1
LINC00337
Intron
SCLC-P


chr1: 6236597
ENST00000650463.1
LINC00337
Intron
SCLC-P


chr1: 6236676
ENST00000650463.1
LINC00337
Intron
SCLC-P


chr1: 6236710
ENST00000650463.1
LINC00337
Intron
SCLC-P


chr1: 6236851
ENST00000650463.1
LINC00337
Intron
SCLC-P


chr1: 6236867
ENST00000650463.1
LINC00337
Intron
SCLC-P


chr1: 6236927
ENST00000650463.1
LINC00337
Intron
SCLC-P


chr1: 6236938
ENST00000650463.1
LINC00337
Intron
SCLC-P


chr1: 6236973
ENST00000650463.1
LINC00337
Intron
SCLC-P


chr1: 6236983
ENST00000650463.1
LINC00337
Intron
SCLC-P


chr1: 6236993
ENST00000650463.1
LINC00337
Intron
SCLC-P


chr1: 6430838
ENST00000645284.1
ESPN
Intron
SCLC-P


chr1: 6451836
ENST00000477679.2
ESPN
Exon
SCLC-P


chr1: 6460544
ENST00000645284.1
ESPN
Exon
SCLC-P


chr1: 6460550
ENST00000645284.1
ESPN
Exon
SCLC-P


chr1: 6460619
ENST00000645284.1
ESPN
Exon
SCLC-P


chr1: 6460623
ENST00000645284.1
ESPN
Exon
SCLC-P


chr1: 6460654
ENST00000645284.1
ESPN
Exon
SCLC-P


chr1: 6460770
ENST00000645284.1
ESPN
Exon
SCLC-P


chr1: 6460775
ENST00000645284.1
ESPN
Exon
SCLC-P


chr1: 6460795
ENST00000645284.1
ESPN
Exon
SCLC-P


chr1: 6460801
ENST00000645284.1
ESPN
Exon
SCLC-P


chr1: 6460819
ENST00000645284.1
ESPN
Exon
SCLC-P


chr1: 6460881
ENST00000645284.1
ESPN
Exon
SCLC-P


chr1: 6460882
ENST00000645284.1
ESPN
Exon
SCLC-P


chr1: 6460893
ENST00000645284.1
ESPN
Exon
SCLC-P


chr1: 6460901
ENST00000645284.1
ESPN
Exon
SCLC-P


chr1: 6460917
ENST00000645284.1
ESPN
Exon
SCLC-P


chr1: 6460918
ENST00000645284.1
ESPN
Exon
SCLC-P


chr1: 6460934
ENST00000645284.1
ESPN
Exon
SCLC-P


chr1: 6460935
ENST00000645284.1
ESPN
Exon
SCLC-P


chr1: 6460948
ENST00000434576.2
ESPN
Intron
SCLC-P


chr1: 6460957
ENST00000434576.2
ESPN
Intron
SCLC-P


chr1: 6460958
ENST00000434576.2
ESPN
Intron
SCLC-P


chr1: 6460959
ENST00000434576.2
ESPN
Intron
SCLC-P


chr1: 6461061
ENST00000434576.2
ESPN
Intron
SCLC-P


chr1: 6461062
ENST00000434576.2
ESPN
Intron
SCLC-P


chr1: 6461078
ENST00000434576.2
ESPN
Intron
SCLC-P


chr1: 6461087
ENST00000434576.2
ESPN
Intron
SCLC-P


chr1: 6461096
ENST00000434576.2
ESPN
Intron
SCLC-P


chr1: 6461192
ENST00000647810.1
TNFRSF25
Exon
SCLC-P


chr1: 6461209
ENST00000647810.1
TNFRSF25
Exon
SCLC-P


chr1: 6461243
ENST00000647810.1
TNFRSF25
Exon
SCLC-P


chr1: 6461250
ENST00000647810.1
TNFRSF25
Exon
SCLC-P


chr1: 6461254
ENST00000647810.1
TNFRSF25
Exon
SCLC-P


chr1: 6461265
ENST00000647810.1
TNFRSF25
Exon
SCLC-P


chr1: 6461279
ENST00000647810.1
TNFRSF25
Exon
SCLC-P


chr1: 6461288
ENST00000647810.1
TNFRSF25
Exon
SCLC-P


chr1: 6461304
ENST00000647810.1
TNFRSF25
Exon
SCLC-P


chr1: 6471003
ENST00000487949.4
PLEKHG5
Exon
SCLC-P


chr1: 6471019
ENST00000487949.4
PLEKHG5
Exon
SCLC-P


chr1: 6471021
ENST00000487949.4
PLEKHG5
Exon
SCLC-P


chr1: 6471022
ENST00000487949.4
PLEKHG5
Exon
SCLC-P


chr1: 6471033
ENST00000487949.4
PLEKHG5
Exon
SCLC-P


chr1: 6471034
ENST00000487949.4
PLEKHG5
Exon
SCLC-P


chr1: 6471072
ENST00000487949.4
PLEKHG5
Exon
SCLC-P


chr1: 6471092
ENST00000487949.4
PLEKHG5
Exon
SCLC-P


chr1: 6471097
ENST00000487949.4
PLEKHG5
Exon
SCLC-P


chr1: 6471160
ENST00000487949.4
PLEKHG5
Exon
SCLC-P


chr1: 6471162
ENST00000487949.4
PLEKHG5
Exon
SCLC-P


chr1: 6471169
ENST00000487949.4
PLEKHG5
Exon
SCLC-P


chr1: 6471174
ENST00000487949.4
PLEKHG5
Exon
SCLC-P


chr1: 6471179
ENST00000487949.4
PLEKHG5
Exon
SCLC-P


chr1: 6471180
ENST00000487949.4
PLEKHG5
Exon
SCLC-P


chr1: 6471200
ENST00000487949.4
PLEKHG5
Exon
SCLC-P


chr1: 6905286
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 6905292
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 6916294
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 6961465
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 6961475
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 6961486
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 6961552
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7049116
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7049123
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7062579
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7062580
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7062581
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7068684
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7090119
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7096454
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7131777
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7131793
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7131821
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7131826
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7145731
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7146227
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7146256
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7155183
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7214613
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7236555
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7236566
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7237778
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7259296
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7347129
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7347138
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7347156
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7347168
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7347171
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7347251
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7351249
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7408068
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7408095
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7408210
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7432317
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7432451
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7432617
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7432621
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7502058
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7502152
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7503063
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7513634
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7524859
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7524905
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7531615
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7533109
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7535115
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7550312
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7550446
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7557372
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7557380
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7557491
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7573817
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7578510
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7578519
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7578528
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7578531
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7583492
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7585015
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7611708
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7613020
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7616494
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7629361
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7633574
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7635642
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7635659
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7640406
ENST00000303635.12
CAMTA1
Exon
SCLC-P


chr1: 7640412
ENST00000303635.12
CAMTA1
Exon
SCLC-P


chr1: 7640433
ENST00000303635.12
CAMTA1
Exon
SCLC-P


chr1: 7640649
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7640650
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7640655
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7640656
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7640688
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7640689
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7642459
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7642467
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7642468
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7642486
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7642487
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7642500
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7648492
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7648558
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7648631
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7660832
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7686766
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7688304
ENST00000303635.12
CAMTA1
Intron
SCLC-P


chr1: 7991044
ENST00000641354.1
NA
Promoter
SCLC-P


chr1: 8201287
ENST00000670361.1
LINC01714
Promoter
SCLC-P


chr1: 8211168
ENST00000670361.1
LINC01714
Intron
SCLC-P


chr1: 8211188
ENST00000670361.1
LINC01714
Intron
SCLC-P


chr1: 8324735
ENST00000471889.5
SLC45A1
Intron
SCLC-P


chr1: 8324746
ENST00000471889.5
SLC45A1
Intron
SCLC-P


chr1: 8339445
ENST00000471889.5
SLC45A1
Intron
SCLC-P


chr1: 8339458
ENST00000471889.5
SLC45A1
Intron
SCLC-P


chr1: 8339529
ENST00000471889.5
SLC45A1
Exon
SCLC-P


chr1: 8339555
ENST00000471889.5
SLC45A1
Exon
SCLC-P


chr1: 8339561
ENST00000471889.5
SLC45A1
Exon
SCLC-P


chr1: 8339573
ENST00000471889.5
SLC45A1
Exon
SCLC-P


chr1: 8395192
ENST00000337907.7
RERE
Intron
SCLC-P


chr1: 8515383
ENST00000507012.1
RERE
Intron
SCLC-P


chr1: 8610066
ENST00000514428.1
RERE
Intron
SCLC-P


chr1: 8871259
ENST00000646680.1
ENO1
Intron
SCLC-P


chr1: 8879289
ENST00000643438.1
ENO1
Promoter
SCLC-P


chr1: 9320710
ENST00000328089.11
SPSB1
Intron
SCLC-P


chr1: 9320840
ENST00000328089.11
SPSB1
Intron
SCLC-P


chr1: 9320847
ENST00000328089.11
SPSB1
Intron
SCLC-P


chr1: 9320850
ENST00000328089.11
SPSB1
Intron
SCLC-P


chr1: 9541107
ENST00000302692.7
SLC25A33
Intron
SCLC-P


chr1: 9541129
ENST00000302692.7
SLC25A33
Intron
SCLC-P


chr1: 9541130
ENST00000302692.7
SLC25A33
Intron
SCLC-P


chr1: 9541177
ENST00000302692.7
SLC25A33
Intron
SCLC-P


chr1: 9541184
ENST00000302692.7
SLC25A33
Intron
SCLC-P


chr1: 9541185
ENST00000302692.7
SLC25A33
Intron
SCLC-P


chr1: 9541214
ENST00000302692.7
SLC25A33
Intron
SCLC-P


chr1: 9541215
ENST00000302692.7
SLC25A33
Intron
SCLC-P


chr1: 9541239
ENST00000302692.7
SLC25A33
Intron
SCLC-P


chr1: 9541240
ENST00000302692.7
SLC25A33
Intron
SCLC-P


chr1: 9541246
ENST00000302692.7
SLC25A33
Intron
SCLC-P


chr1: 9541247
ENST00000302692.7
SLC25A33
Intron
SCLC-P


chr1: 9541254
ENST00000302692.7
SLC25A33
Intron
SCLC-P


chr1: 9541278
ENST00000302692.7
SLC25A33
Intron
SCLC-P


chr1: 9541302
ENST00000302692.7
SLC25A33
Intron
SCLC-P


chr1: 9541444
ENST00000302692.7
SLC25A33
Intron
SCLC-P


chr1: 9541450
ENST00000302692.7
SLC25A33
Intron
SCLC-P


chr1: 9541485
ENST00000302692.7
SLC25A33
Intron
SCLC-P


chr1: 9542000
ENST00000302692.7
SLC25A33
Intron
SCLC-P


chr1: 9949211
ENST00000445884.1
NMNAT1
Intron
SCLC-P


chr1: 10399714
ENST00000487775.1
PGD
Exon
SCLC-P


chr1: 10491872
ENST00000472851.1
PEX14
Intron
SCLC-P


chr1: 10614772
ENST00000356607.9
PEX14
Intron
SCLC-P


chr1: 10614960
ENST00000356607.9
PEX14
Intron
SCLC-P


chr1: 10638287
ENST00000377022.8
CASZ1
Exon
SCLC-P


chr1: 10638331
ENST00000377022.8
CASZ1
Exon
SCLC-P


chr1: 10643732
ENST00000606802.1
NA
Intron
SCLC-P


chr1: 10666482
ENST00000377022.8
CASZ1
Intron
SCLC-P


chr1: 10666544
ENST00000377022.8
CASZ1
Intron
SCLC-P


chr1: 11027945
ENST00000614757.4
TARDBP
Intron
SCLC-P


chr1: 11032484
ENST00000400897.8
MASP2
Intron
SCLC-P


chr1: 11033047
ENST00000400897.8
MASP2
Intron
SCLC-P


chr1: 11033051
ENST00000400897.8
MASP2
Intron
SCLC-P


chr1: 11519397
ENST00000294484.7
DISP3
Exon
SCLC-P


chr1: 11519418
ENST00000294484.7
DISP3
Exon
SCLC-P


chr1: 11520613
ENST00000294484.7
DISP3
Intron
SCLC-P


chr1: 11521111
ENST00000294484.7
DISP3
Intron
SCLC-P


chr1: 11529915
ENST00000294484.7
DISP3
Exon
SCLC-P


chr1: 11529945
ENST00000294484.7
DISP3
Exon
SCLC-P


chr1: 11531203
ENST00000294484.7
DISP3
Intron
SCLC-P


chr1: 11531653
ENST00000294484.7
DISP3
Exon
SCLC-P


chr1: 11531665
ENST00000294484.7
DISP3
Exon
SCLC-P


chr1: 11531678
ENST00000294484.7
DISP3
Exon
SCLC-P


chr1: 11531680
ENST00000294484.7
DISP3
Exon
SCLC-P


chr1: 11531710
ENST00000294484.7
DISP3
Exon
SCLC-P


chr1: 11531746
ENST00000294484.7
DISP3
Intron
SCLC-P


chr1: 11531756
ENST00000294484.7
DISP3
Intron
SCLC-P


chr1: 11532110
ENST00000294484.7
DISP3
Intron
SCLC-P


chr1: 11534489
ENST00000294484.7
DISP3
Exon
SCLC-P


chr1: 11534506
ENST00000294484.7
DISP3
Exon
SCLC-P


chr1: 11534536
ENST00000294484.7
DISP3
Exon
SCLC-P


chr1: 11534600
ENST00000294484.7
DISP3
Intron
SCLC-P


chr1: 11534660
ENST00000294484.7
DISP3
Intron
SCLC-P


chr1: 11534828
ENST00000294484.7
DISP3
Intron
SCLC-P


chr1: 11536648
ENST00000294484.7
DISP3
Exon
SCLC-P


chr1: 11536669
ENST00000294484.7
DISP3
Exon
SCLC-P


chr1: 11536690
ENST00000294484.7
DISP3
Exon
SCLC-P


chr1: 11536894
ENST00000294484.7
DISP3
Exon
SCLC-P


chr1: 11635902
ENST00000642131.1
NA
Intron
SCLC-P


chr1: 11636023
ENST00000642131.1
NA
Intron
SCLC-P


chr1: 11636036
ENST00000642131.1
NA
Intron
SCLC-P


chr1: 11638777
ENST00000642131.1
NA
Intron
SCLC-P


chr1: 11648235
ENST00000642025.1
FBXO2
Exon
SCLC-P


chr1: 11648320
ENST00000642025.1
FBXO2
Exon
SCLC-P


chr1: 11650911
ENST00000471501.1
FBXO2
Promoter
SCLC-P


chr1: 11692562
ENST00000376655.1
MAD2L2
Promoter
SCLC-P


chr1: 11765872
ENST00000484153.1
C1orf167
Promoter
SCLC-P


chr1: 11766722
ENST00000484153.1
C1orf167
Promoter
SCLC-P


chr1: 11858331
ENST00000376468.4
NPPB
Exon
SCLC-P


chr1: 11858340
ENST00000376468.4
NPPB
Exon
SCLC-P


chr1: 11858350
ENST00000376468.4
NPPB
Exon
SCLC-P


chr1: 11858364
ENST00000376468.4
NPPB
Exon
SCLC-P


chr1: 11878068
ENST00000438808.1
NA
Exon
SCLC-P


chr1: 11878785
ENST00000438808.1
NA
Exon
SCLC-P


chr1: 11878943
ENST00000438808.1
NA
Exon
SCLC-P


chr1: 11937143
ENST00000485046.5
PLOD1
Intron
SCLC-P


chr1: 11937178
ENST00000485046.5
PLOD1
Intron
SCLC-P


chr1: 11937204
ENST00000485046.5
PLOD1
Intron
SCLC-P


chr1: 11937270
ENST00000485046.5
PLOD1
Intron
SCLC-P


chr1: 11937286
ENST00000485046.5
PLOD1
Intron
SCLC-P


chr1: 11937599
ENST00000485046.5
PLOD1
Intron
SCLC-P


chr1: 11937621
ENST00000485046.5
PLOD1
Intron
SCLC-P


chr1: 11941809
ENST00000485046.5
PLOD1
Intron
SCLC-P


chr1: 12020671
ENST00000478749.5
MIIP
Intron
SCLC-P


chr1: 12020706
ENST00000478749.5
MIIP
Intron
SCLC-P


chr1: 12141637
ENST00000479933.2
TNFRSF8
Intron
SCLC-P


chr1: 12143533
ENST00000263932.7
TNFRSF8
Exon
SCLC-P


chr1: 12143563
ENST00000263932.7
TNFRSF8
Exon
SCLC-P


chr1: 12143575
ENST00000263932.7
TNFRSF8
Exon
SCLC-P


chr1: 13490926
ENST00000376085.4
LRRC38
Intron
SCLC-P


chr1: 14971957
ENST00000636203.1
KAZN
Intron
SCLC-P


chr1: 15091510
ENST00000636203.1
KAZN
Intron
SCLC-P


chr1: 15091551
ENST00000636203.1
KAZN
Intron
SCLC-P


chr1: 15094806
ENST00000636203.1
KAZN
Intron
SCLC-P


chr1: 15094835
ENST00000636203.1
KAZN
Exon
SCLC-P


chr1: 15094881
ENST00000636203.1
KAZN
Exon
SCLC-P


chr1: 15094890
ENST00000636203.1
KAZN
Exon
SCLC-P


chr1: 15094901
ENST00000636203.1
KAZN
Exon
SCLC-P


chr1: 15094919
ENST00000636203.1
KAZN
Exon
SCLC-P


chr1: 15094947
ENST00000636203.1
KAZN
Intron
SCLC-P


chr1: 15094956
ENST00000636203.1
KAZN
Intron
SCLC-P


chr1: 15094957
ENST00000636203.1
KAZN
Intron
SCLC-P


chr1: 15095070
ENST00000636203.1
KAZN
Intron
SCLC-P


chr1: 15095198
ENST00000636203.1
KAZN
Intron
SCLC-P


chr1: 15095209
ENST00000636203.1
KAZN
Intron
SCLC-P


chr1: 15095236
ENST00000636203.1
KAZN
Intron
SCLC-P


chr1: 15170295
ENST00000428417.5
TMEM51
Intron
SCLC-P


chr1: 15176385
ENST00000428417.5
TMEM51
Intron
SCLC-P


chr1: 15176487
ENST00000428417.5
TMEM51
Intron
SCLC-P


chr1: 15207320
ENST00000428417.5
TMEM51
Intron
SCLC-P


chr1: 15207443
ENST00000428417.5
TMEM51
Intron
SCLC-P


chr1: 15207597
ENST00000428417.5
TMEM51
Intron
SCLC-P


chr1: 15207633
ENST00000428417.5
TMEM51
Intron
SCLC-P


chr1: 15207848
ENST00000428417.5
TMEM51
Intron
SCLC-P


chr1: 15284221
ENST00000433640.6
FHAD1
Intron
SCLC-P


chr1: 15284246
ENST00000433640.6
FHAD1
Intron
SCLC-P


chr1: 15284247
ENST00000433640.6
FHAD1
Intron
SCLC-P


chr1: 15284251
ENST00000433640.6
FHAD1
Intron
SCLC-P


chr1: 15284252
ENST00000433640.6
FHAD1
Intron
SCLC-P


chr1: 15284256
ENST00000433640.6
FHAD1
Intron
SCLC-P


chr1: 15284262
ENST00000433640.6
FHAD1
Intron
SCLC-P


chr1: 15284296
ENST00000433640.6
FHAD1
Intron
SCLC-P


chr1: 15284297
ENST00000433640.6
FHAD1
Intron
SCLC-P


chr1: 15314484
ENST00000524761.5
FHAD1
Intron
SCLC-P


chr1: 15378800
ENST00000358897.8
FHAD1
Intron
SCLC-P


chr1: 15378835
ENST00000358897.8
FHAD1
Intron
SCLC-P


chr1: 15467428
ENST00000359621.5
CELA2A
Exon
SCLC-P


chr1: 15467442
ENST00000359621.5
CELA2A
Exon
SCLC-P


chr1: 15467448
ENST00000359621.5
CELA2A
Exon
SCLC-P


chr1: 15467464
ENST00000359621.5
CELA2A
Exon
SCLC-P


chr1: 15467505
ENST00000359621.5
CELA2A
Exon
SCLC-P


chr1: 15467507
ENST00000359621.5
CELA2A
Exon
SCLC-P


chr1: 15467538
ENST00000359621.5
CELA2A
Exon
SCLC-P


chr1: 15467548
ENST00000494280.1
CELA2B
Intron
SCLC-P


chr1: 15619223
ENST00000480945.6
DDI2
Intron
SCLC-P


chr1: 15619262
ENST00000480945.6
DDI2
Intron
SCLC-P


chr1: 15619265
ENST00000480945.6
DDI2
Intron
SCLC-P


chr1: 15619266
ENST00000480945.6
DDI2
Intron
SCLC-P


chr1: 15619267
ENST00000480945.6
DDI2
Intron
SCLC-P


chr1: 15619268
ENST00000480945.6
DDI2
Intron
SCLC-P


chr1: 15619269
ENST00000480945.6
DDI2
Intron
SCLC-P


chr1: 15619270
ENST00000480945.6
DDI2
Intron
SCLC-P


chr1: 15619278
ENST00000480945.6
DDI2
Intron
SCLC-P


chr1: 15619372
ENST00000480945.6
DDI2
Intron
SCLC-P


chr1: 15619373
ENST00000480945.6
DDI2
Intron
SCLC-P


chr1: 15619377
ENST00000480945.6
DDI2
Intron
SCLC-P


chr1: 15619378
ENST00000480945.6
DDI2
Intron
SCLC-P


chr1: 15619395
ENST00000480945.6
DDI2
Intron
SCLC-P


chr1: 15619396
ENST00000480945.6
DDI2
Intron
SCLC-P


chr1: 15619415
ENST00000480945.6
DDI2
Intron
SCLC-P


chr1: 15619416
ENST00000480945.6
DDI2
Intron
SCLC-P


chr1: 15619421
ENST00000480945.6
DDI2
Intron
SCLC-P


chr1: 15619422
ENST00000480945.6
DDI2
Intron
SCLC-P


chr1: 15619483
ENST00000480945.6
DDI2
Intron
SCLC-P


chr1: 15619484
ENST00000480945.6
DDI2
Intron
SCLC-P


chr1: 15619488
ENST00000480945.6
DDI2
Intron
SCLC-P


chr1: 15619489
ENST00000480945.6
DDI2
Intron
SCLC-P


chr1: 15619500
ENST00000480945.6
DDI2
Intron
SCLC-P


chr1: 15619501
ENST00000480945.6
DDI2
Intron
SCLC-P


chr1: 15619522
ENST00000480945.6
DDI2
Intron
SCLC-P


chr1: 15619524
ENST00000480945.6
DDI2
Intron
SCLC-P


chr1: 15619525
ENST00000480945.6
DDI2
Intron
SCLC-P


chr1: 15619530
ENST00000480945.6
DDI2
Intron
SCLC-P


chr1: 15619531
ENST00000480945.6
DDI2
Intron
SCLC-P


chr1: 15619554
ENST00000480945.6
DDI2
Intron
SCLC-P


chr1: 15619555
ENST00000480945.6
DDI2
Intron
SCLC-P


chr1: 15619560
ENST00000480945.6
DDI2
Intron
SCLC-P


chr1: 15619561
ENST00000480945.6
DDI2
Intron
SCLC-P


chr1: 15619587
ENST00000480945.6
DDI2
Intron
SCLC-P


chr1: 15619697
ENST00000480945.6
DDI2
Intron
SCLC-P


chr1: 15619708
ENST00000480945.6
DDI2
Intron
SCLC-P


chr1: 15619713
ENST00000480945.6
DDI2
Intron
SCLC-P


chr1: 15619739
ENST00000480945.6
DDI2
Intron
SCLC-P


chr1: 15619745
ENST00000480945.6
DDI2
Intron
SCLC-P


chr1: 15974871
ENST00000375743.8
ZBTB17
Intron
SCLC-P


chr1: 16360965
ENST00000475078.1
SZRD1
Intron
SCLC-P


chr1: 16612139
ENST00000430580.6
NBPF1
Intron
SCLC-P


chr1: 16612246
ENST00000430580.6
NBPF1
Intron
SCLC-P


chr1: 16612282
ENST00000430580.6
NBPF1
Intron
SCLC-P


chr1: 16612286
ENST00000430580.6
NBPF1
Intron
SCLC-P


chr1: 17008777
ENST00000341676.9
ATP13A2
Intron
SCLC-P


chr1: 17008821
ENST00000341676.9
ATP13A2
Intron
SCLC-P


chr1: 17413855
ENST00000375436.9
RCC2
Intron
SCLC-P


chr1: 17427886
ENST00000375436.9
RCC2
Intron
SCLC-P


chr1: 17427912
ENST00000375436.9
RCC2
Intron
SCLC-P


chr1: 17427919
ENST00000375436.9
RCC2
Intron
SCLC-P


chr1: 18252569
ENST00000251296.4
IGSF21
Intron
SCLC-P


chr1: 18252756
ENST00000251296.4
IGSF21
Intron
SCLC-P


chr1: 18252757
ENST00000251296.4
IGSF21
Intron
SCLC-P


chr1: 18252764
ENST00000251296.4
IGSF21
Intron
SCLC-P


chr1: 18262355
ENST00000251296.4
IGSF21
Intron
SCLC-P


chr1: 18268619
ENST00000251296.4
IGSF21
Intron
SCLC-P


chr1: 18269952
ENST00000251296.4
IGSF21
Intron
SCLC-P


chr1: 18270018
ENST00000251296.4
IGSF21
Intron
SCLC-P


chr1: 18282229
ENST00000251296.4
IGSF21
Intron
SCLC-P


chr1: 18291342
ENST00000251296.4
IGSF21
Intron
SCLC-P


chr1: 18291456
ENST00000251296.4
IGSF21
Intron
SCLC-P


chr1: 18296112
ENST00000251296.4
IGSF21
Intron
SCLC-P


chr1: 18925512
ENST00000455833.7
IFFO2
Intron
SCLC-P


chr1: 19366460
ENST00000264202.8
CAPZB
Intron
SCLC-P


chr1: 19477027
ENST00000459967.6
CAPZB
Intron
SCLC-P


chr1: 19920429
ENST00000375116.3
PLA2G2E
Exon
SCLC-P


chr1: 19920447
ENST00000375116.3
PLA2G2E
Exon
SCLC-P


chr1: 19920448
ENST00000375116.3
PLA2G2E
Exon
SCLC-P


chr1: 19920690
ENST00000375116.3
PLA2G2E
Intron
SCLC-P


chr1: 19922634
ENST00000375116.3
PLA2G2E
Exon
SCLC-P


chr1: 19922651
ENST00000375116.3
PLA2G2E
Exon
SCLC-P


chr1: 19922657
ENST00000375116.3
PLA2G2E
Exon
SCLC-P


chr1: 19922712
ENST00000375116.3
PLA2G2E
Exon
SCLC-P


chr1: 20165043
ENST00000495760.2
PLA2G2C
Intron
SCLC-P


chr1: 20336453
ENST00000485375.6
VWA5B1
Exon
SCLC-P


chr1: 20721988
ENST00000444387.7
SH2D5
Exon
SCLC-P


chr1: 21547931
ENST00000468526.1
ALPL
Intron
SCLC-P


chr1: 21548030
ENST00000468526.1
ALPL
Intron
SCLC-P


chr1: 21548121
ENST00000468526.1
ALPL
Intron
SCLC-P


chr1: 21597784
ENST00000290101.8
RAP1GAP
Intron
SCLC-P


chr1: 21603872
ENST00000611549.4
RAP1GAP
Exon
SCLC-P


chr1: 21619318
ENST00000290101.8
RAP1GAP
Intron
SCLC-P


chr1: 21627288
ENST00000290101.8
RAP1GAP
Intron
SCLC-P


chr1: 21664057
ENST00000290101.8
RAP1GAP
Intron
SCLC-P


chr1: 21664061
ENST00000290101.8
RAP1GAP
Intron
SCLC-P


chr1: 22589212
ENST00000374644.8
EPHA8
Exon
SCLC-P


chr1: 22591874
ENST00000166244.8
EPHA8
Intron
SCLC-P


chr1: 22597780
ENST00000166244.8
EPHA8
Exon
SCLC-P


chr1: 22597794
ENST00000166244.8
EPHA8
Exon
SCLC-P


chr1: 22597799
ENST00000166244.8
EPHA8
Exon
SCLC-P


chr1: 22598934
ENST00000166244.8
EPHA8
Exon
SCLC-P


chr1: 22601202
ENST00000166244.8
EPHA8
Intron
SCLC-P


chr1: 22601203
ENST00000166244.8
EPHA8
Intron
SCLC-P


chr1: 22643723
ENST00000374639.7
C1QC
UTR5
SCLC-P


chr1: 22643769
ENST00000374637.1
C1QC
UTR5
SCLC-P


chr1: 22739946
ENST00000544305.5
EPHB2
Intron
SCLC-P


chr1: 22963336
ENST00000618559.1
LACTBL1
Promoter
SCLC-P


chr1: 24385760
ENST00000003583.12
STPG1
Intron
SCLC-P


chr1: 24744410
ENST00000497755.1
CLIC4
Promoter
SCLC-P


chr1: 24744411
ENST00000497755.1
CLIC4
Promoter
SCLC-P


chr1: 24744414
ENST00000497755.1
CLIC4
Promoter
SCLC-P


chr1: 24744415
ENST00000497755.1
CLIC4
Promoter
SCLC-P


chr1: 24744417
ENST00000497755.1
CLIC4
Promoter
SCLC-P


chr1: 24744419
ENST00000497755.1
CLIC4
Promoter
SCLC-P


chr1: 24744429
ENST00000497755.1
CLIC4
Promoter
SCLC-P


chr1: 24744466
ENST00000497755.1
CLIC4
Promoter
SCLC-P


chr1: 25809315
ENST00000354177.8
SELENON
Intron
SCLC-P


chr1: 25809316
ENST00000354177.8
SELENON
Intron
SCLC-P


chr1: 25809343
ENST00000354177.8
SELENON
Intron
SCLC-P


chr1: 28583630
ENST00000488745.5
SNHG12
Promoter
SCLC-P


chr1: 28583631
ENST00000488745.5
SNHG12
Promoter
SCLC-P


chr1: 28583644
ENST00000488745.5
SNHG12
Promoter
SCLC-P


chr1: 28583656
ENST00000488745.5
SNHG12
Promoter
SCLC-P


chr1: 28583660
ENST00000488745.5
SNHG12
Promoter
SCLC-P


chr1: 28583661
ENST00000488745.5
SNHG12
Promoter
SCLC-P


chr1: 28583690
ENST00000488745.5
SNHG12
Promoter
SCLC-P


chr1: 28583698
ENST00000488745.5
SNHG12
Promoter
SCLC-P


chr1: 28583700
ENST00000488745.5
SNHG12
Promoter
SCLC-P


chr1: 28583701
ENST00000488745.5
SNHG12
Promoter
SCLC-P


chr1: 28583705
ENST00000488745.5
SNHG12
Promoter
SCLC-P


chr1: 28715324
ENST00000373816.5
GMEB1
Exon
SCLC-P


chr1: 28715336
ENST00000373816.5
GMEB1
Exon
SCLC-P


chr1: 28715337
ENST00000373816.5
GMEB1
Exon
SCLC-P


chr1: 28715364
ENST00000373816.5
GMEB1
Exon
SCLC-P


chr1: 28715380
ENST00000373816.5
GMEB1
Exon
SCLC-P


chr1: 31669817
ENST00000468459.5
COL16A1
Intron
SCLC-P


chr1: 31669823
ENST00000468459.5
COL16A1
Intron
SCLC-P


chr1: 31669841
ENST00000468459.5
COL16A1
Intron
SCLC-P


chr1: 32674128
ENST00000373485.5
RBBP4
Intron
SCLC-P


chr1: 33625012
ENST00000373381.8
CSMD2
Intron
SCLC-P


chr1: 33625019
ENST00000373381.8
CSMD2
Intron
SCLC-P


chr1: 33625030
ENST00000373381.8
CSMD2
Intron
SCLC-P


chr1: 33625034
ENST00000373381.8
CSMD2
Intron
SCLC-P


chr1: 33625058
ENST00000373377.1
CSMD2
UTR5
SCLC-P


chr1: 33625064
ENST00000373377.1
CSMD2
UTR5
SCLC-P


chr1: 34153164
ENST00000373388.6
CSMD2
Intron
SCLC-P


chr1: 34887201
ENST00000235180.4
DLGAP3
Intron
SCLC-P


chr1: 34887202
ENST00000235180.4
DLGAP3
Intron
SCLC-P


chr1: 34887206
ENST00000235180.4
DLGAP3
Intron
SCLC-P


chr1: 34887207
ENST00000235180.4
DLGAP3
Intron
SCLC-P


chr1: 34887234
ENST00000235180.4
DLGAP3
Intron
SCLC-P


chr1: 34887235
ENST00000235180.4
DLGAP3
Intron
SCLC-P


chr1: 34887244
ENST00000235180.4
DLGAP3
Intron
SCLC-P


chr1: 34887245
ENST00000235180.4
DLGAP3
Intron
SCLC-P


chr1: 34904362
ENST00000373347.6
DLGAP3
Exon
SCLC-P


chr1: 34904494
ENST00000373347.6
DLGAP3
Exon
SCLC-P


chr1: 35560570
ENST00000373253.7
NCDN
Exon
SCLC-P


chr1: 36867899
ENST00000373091.8
GRIK3
Intron
SCLC-P


chr1: 36868049
ENST00000373091.8
GRIK3
Intron
SCLC-P


chr1: 36966667
ENST00000373091.8
GRIK3
Intron
SCLC-P


chr1: 36966850
ENST00000373091.8
GRIK3
Intron
SCLC-P


chr1: 37448607
ENST00000668045.1
LINC01137
Intron
SCLC-P


chr1: 37452230
ENST00000668045.1
LINC01137
Intron
SCLC-P


chr1: 37452442
ENST00000668045.1
LINC01137
Intron
SCLC-P


chr1: 37475662
ENST00000640233.1
ZC3H12A
Exon
SCLC-P


chr1: 37475697
ENST00000640233.1
ZC3H12A
Exon
SCLC-P


chr1: 37475773
ENST00000640233.1
ZC3H12A
Exon
SCLC-P


chr1: 37475777
ENST00000640233.1
ZC3H12A
Exon
SCLC-P


chr1: 37475783
ENST00000640233.1
ZC3H12A
Exon
SCLC-P


chr1: 37475796
ENST00000640233.1
ZC3H12A
Exon
SCLC-P


chr1: 37719021
ENST00000534097.5
EPHA10
Intron
SCLC-P


chr1: 37719040
ENST00000534097.5
EPHA10
Intron
SCLC-P


chr1: 37719045
ENST00000534097.5
EPHA10
Intron
SCLC-P


chr1: 37719046
ENST00000534097.5
EPHA10
Intron
SCLC-P


chr1: 37736214
ENST00000446149.6
EPHA10
Intron
SCLC-P


chr1: 38052629
ENST00000432922.5
NA
Intron
SCLC-P


chr1: 38052644
ENST00000432922.5
NA
Intron
SCLC-P


chr1: 38052658
ENST00000432922.5
NA
Intron
SCLC-P


chr1: 38052759
ENST00000432922.5
NA
Intron
SCLC-P


chr1: 38062291
ENST00000432922.5
NA
Intron
SCLC-P


chr1: 38086104
ENST00000432922.5
NA
Intron
SCLC-P


chr1: 38136298
ENST00000641212.1
NA
Exon
SCLC-P


chr1: 38137909
ENST00000641212.1
NA
Intron
SCLC-P


chr1: 38137950
ENST00000641212.1
NA
Intron
SCLC-P


chr1: 40770819
ENST00000414185.1
NFYC
Intron
SCLC-P


chr1: 40770919
ENST00000414185.1
NFYC
Intron
SCLC-P


chr1: 42887980
ENST00000448759.1
NA
Exon
SCLC-P


chr1: 42887991
ENST00000448759.1
NA
Exon
SCLC-P


chr1: 45444036
ENST00000671898.1
MUTYH
Intron
SCLC-P


chr1: 45583057
ENST00000437901.6
NASP
Promoter
SCLC-P


chr1: 45622828
ENST00000445048.2
CCDC17
Intron
SCLC-P


chr1: 45622851
ENST00000445048.2
CCDC17
Intron
SCLC-P


chr1: 45622853
ENST00000445048.2
CCDC17
Intron
SCLC-P


chr1: 45622870
ENST00000445048.2
CCDC17
Intron
SCLC-P


chr1: 45622929
ENST00000445048.2
CCDC17
Intron
SCLC-P


chr1: 45622937
ENST00000445048.2
CCDC17
Intron
SCLC-P


chr1: 45622945
ENST00000445048.2
CCDC17
Intron
SCLC-P


chr1: 45622963
ENST00000445048.2
CCDC17
Intron
SCLC-P


chr1: 45622983
ENST00000445048.2
CCDC17
Intron
SCLC-P


chr1: 45623010
ENST00000445048.2
CCDC17
Intron
SCLC-P


chr1: 45623011
ENST00000445048.2
CCDC17
Intron
SCLC-P


chr1: 45623012
ENST00000445048.2
CCDC17
Intron
SCLC-P


chr1: 45623019
ENST00000445048.2
CCDC17
Intron
SCLC-P


chr1: 45623020
ENST00000445048.2
CCDC17
Intron
SCLC-P


chr1: 45623058
ENST00000445048.2
CCDC17
Intron
SCLC-P


chr1: 45623059
ENST00000445048.2
CCDC17
Intron
SCLC-P


chr1: 45623066
ENST00000445048.2
CCDC17
Intron
SCLC-P


chr1: 45623067
ENST00000445048.2
CCDC17
Intron
SCLC-P


chr1: 45623076
ENST00000445048.2
CCDC17
Intron
SCLC-P


chr1: 45623077
ENST00000445048.2
CCDC17
Intron
SCLC-P


chr1: 45623081
ENST00000445048.2
CCDC17
Intron
SCLC-P


chr1: 45623082
ENST00000445048.2
CCDC17
Intron
SCLC-P


chr1: 45623083
ENST00000445048.2
CCDC17
Intron
SCLC-P


chr1: 45623084
ENST00000445048.2
CCDC17
Intron
SCLC-P


chr1: 45623105
ENST00000445048.2
CCDC17
Intron
SCLC-P


chr1: 45623106
ENST00000445048.2
CCDC17
Intron
SCLC-P


chr1: 45623108
ENST00000445048.2
CCDC17
Intron
SCLC-P


chr1: 45623109
ENST00000445048.2
CCDC17
Intron
SCLC-P


chr1: 45623129
ENST00000445048.2
CCDC17
Intron
SCLC-P


chr1: 45623130
ENST00000445048.2
CCDC17
Intron
SCLC-P


chr1: 45623134
ENST00000445048.2
CCDC17
Intron
SCLC-P


chr1: 45623145
ENST00000445048.2
CCDC17
Intron
SCLC-P


chr1: 45623150
ENST00000445048.2
CCDC17
Intron
SCLC-P


chr1: 45623151
ENST00000445048.2
CCDC17
Intron
SCLC-P


chr1: 45623169
ENST00000445048.2
CCDC17
Intron
SCLC-P


chr1: 45623172
ENST00000445048.2
CCDC17
Intron
SCLC-P


chr1: 45623199
ENST00000445048.2
CCDC17
Intron
SCLC-P


chr1: 45623221
ENST00000445048.2
CCDC17
Intron
SCLC-P


chr1: 45623224
ENST00000445048.2
CCDC17
Intron
SCLC-P


chr1: 45623226
ENST00000445048.2
CCDC17
Intron
SCLC-P


chr1: 45623241
ENST00000445048.2
CCDC17
Intron
SCLC-P


chr1: 47439324
ENST00000334793.5
FOXD2
Exon
SCLC-P


chr1: 47439345
ENST00000334793.5
FOXD2
Exon
SCLC-P


chr1: 47439462
ENST00000334793.5
FOXD2
Exon
SCLC-P


chr1: 47439464
ENST00000334793.5
FOXD2
Exon
SCLC-P


chr1: 47439522
ENST00000334793.5
FOXD2
Exon
SCLC-P


chr1: 47887584
ENST00000606738.3
TRABD2B
Intron
SCLC-P


chr1: 47924043
ENST00000606738.3
TRABD2B
Intron
SCLC-P


chr1: 47924219
ENST00000606738.3
TRABD2B
Intron
SCLC-P


chr1: 48355580
ENST00000371843.7
SPATA6
Intron
SCLC-P


chr1: 50309008
ENST00000641180.1
NA
Intron
SCLC-P


chr1: 50309014
ENST00000641180.1
NA
Intron
SCLC-P


chr1: 53077723
ENST00000447867.1
NA
Intron
SCLC-P


chr1: 53077739
ENST00000447867.1
NA
Intron
SCLC-P


chr1: 53077838
ENST00000447867.1
NA
Intron
SCLC-P


chr1: 53090927
ENST00000620288.4
SLC1A7
Intron
SCLC-P


chr1: 53836270
ENST00000480952.1
NDC1
Intron
SCLC-P


chr1: 53836274
ENST00000480952.1
NDC1
Intron
SCLC-P


chr1: 53836425
ENST00000480952.1
NDC1
Intron
SCLC-P


chr1: 53836589
ENST00000480952.1
NDC1
Intron
SCLC-P


chr1: 59712748
ENST00000476939.5
FGGY
Intron
SCLC-P


chr1: 62194337
ENST00000498273.2
L1TD1
Promoter
SCLC-P


chr1: 64852033
ENST00000342505.5
JAK1
Intron
SCLC-P


chr1: 64852053
ENST00000342505.5
JAK1
Intron
SCLC-P


chr1: 95228039
ENST00000604534.5
TLCD4-RWDD3
Intron
SCLC-P


chr1: 109294770
ENST00000489706.5
MYBPHL
Intron
SCLC-P


chr1: 110518605
ENST00000369771.4
KCNA10
Exon
SCLC-P


chr1: 110530454
ENST00000640680.1
KCNA2
Intron
SCLC-P


chr1: 110530473
ENST00000640680.1
KCNA2
Intron
SCLC-P


chr1: 111900287
ENST00000369697.5
KCND3
Intron
SCLC-P


chr1: 113906885
ENST00000648795.1
DCLRE1B
Intron
SCLC-P


chr1: 116668193
ENST00000369486.7
IGSF3
Promoter
SCLC-P


chr1: 118985198
ENST00000207157.7
TBX15
Intron
SCLC-P


chr1: 118989370
ENST00000207157.7
TBX15
UTR5
SCLC-P


chr1: 118989427
ENST00000207157.7
TBX15
UTR5
SCLC-P


chr1: 118989611
ENST00000207157.7
TBX15
Promoter
SCLC-P


chr1: 118989698
ENST00000207157.7
TBX15
Promoter
SCLC-P


chr1: 118990071
ENST00000207157.7
TBX15
Promoter
SCLC-P


chr1: 118990113
ENST00000207157.7
TBX15
Promoter
SCLC-P


chr1: 118990150
ENST00000207157.7
TBX15
Promoter
SCLC-P


chr1: 118990209
ENST00000207157.7
TBX15
Promoter
SCLC-P


chr1: 118990303
ENST00000207157.7
TBX15
Promoter
SCLC-P


chr1: 119623849
ENST00000421812.3
ZNF697
Exon
SCLC-P


chr1: 119623858
ENST00000421812.3
ZNF697
Exon
SCLC-P


chr1: 119623861
ENST00000421812.3
ZNF697
Exon
SCLC-P


chr1: 119623868
ENST00000421812.3
ZNF697
Exon
SCLC-P


chr1: 119623882
ENST00000421812.3
ZNF697
Exon
SCLC-P


chr1: 119623888
ENST00000421812.3
ZNF697
Exon
SCLC-P


chr1: 119623889
ENST00000421812.3
ZNF697
Exon
SCLC-P


chr1: 119623910
ENST00000421812.3
ZNF697
Exon
SCLC-P


chr1: 119623926
ENST00000421812.3
ZNF697
Exon
SCLC-P


chr1: 119623936
ENST00000421812.3
ZNF697
Exon
SCLC-P


chr1: 151133216
ENST00000368912.7
SEMA6C
Exon
SCLC-P


chr1: 151133246
ENST00000368912.7
SEMA6C
Exon
SCLC-P


chr1: 151133249
ENST00000368912.7
SEMA6C
Exon
SCLC-P


chr1: 151133258
ENST00000368912.7
SEMA6C
Exon
SCLC-P


chr1: 151133260
ENST00000368912.7
SEMA6C
Exon
SCLC-P


chr1: 151133266
ENST00000368912.7
SEMA6C
Exon
SCLC-P


chr1: 151133385
ENST00000368912.7
SEMA6C
Exon
SCLC-P


chr1: 154503013
ENST00000368482.8
TDRD10
UTR5
SCLC-P


chr1: 154503020
ENST00000368482.8
TDRD10
UTR5
SCLC-P


chr1: 154503022
ENST00000368482.8
TDRD10
UTR5
SCLC-P


chr1: 154503027
ENST00000368482.8
TDRD10
UTR5
SCLC-P


chr1: 156076881
ENST00000532414.3
MEX3A
Exon
SCLC-P


chr1: 156076891
ENST00000532414.3
MEX3A
Exon
SCLC-P


chr1: 161152335
ENST00000467540.5
UFC1
Promoter
SCLC-P


chr1: 161152367
ENST00000467540.5
UFC1
Promoter
SCLC-P


chr1: 161152395
ENST00000467540.5
UFC1
Promoter
SCLC-P


chr1: 161152405
ENST00000467540.5
UFC1
Promoter
SCLC-P


chr1: 161152410
ENST00000467540.5
UFC1
Promoter
SCLC-P


chr1: 161152581
ENST00000467540.5
UFC1
Promoter
SCLC-P


chr1: 161152593
ENST00000467540.5
UFC1
Promoter
SCLC-P


chr1: 161152597
ENST00000467540.5
UFC1
Promoter
SCLC-P


chr1: 161152734
ENST00000467540.5
UFC1
Promoter
SCLC-P


chr1: 161152774
ENST00000467540.5
UFC1
Promoter
SCLC-P


chr1: 161152776
ENST00000467540.5
UFC1
Exon
SCLC-P


chr1: 161152777
ENST00000467540.5
UFC1
Exon
SCLC-P


chr1: 161152778
ENST00000467540.5
UFC1
Exon
SCLC-P


chr1: 161152779
ENST00000467540.5
UFC1
Exon
SCLC-P


chr1: 161152788
ENST00000467540.5
UFC1
Exon
SCLC-P


chr1: 161152789
ENST00000467540.5
UFC1
Exon
SCLC-P


chr1: 161152871
ENST00000467540.5
UFC1
Exon
SCLC-P


chr1: 161152872
ENST00000467540.5
UFC1
Exon
SCLC-P
















TABLE 23







Additional methylation sites associated with the SCLC-I subtype











Methylation Site
Transcript_ID
Gene_Symbol
Gene_Region
Subtype





chr1: 1212968
ENST00000497869.5
TNFRSF4
Intron
SCLC-I


chr1: 3161157
ENST00000511072.5
PRDM16
Intron
SCLC-I


chr1: 5994737
ENST00000655548.1
KCNAB2
Intron
SCLC-I


chr1: 5994749
ENST00000655548.1
KCNAB2
Intron
SCLC-I


chr1: 5994769
ENST00000655548.1
KCNAB2
Intron
SCLC-I


chr1: 5994808
ENST00000655548.1
KCNAB2
Intron
SCLC-I


chr1: 5994858
ENST00000655548.1
KCNAB2
Intron
SCLC-I


chr1: 6455268
ENST00000645284.1
ESPN
Intron
SCLC-I


chr1: 6455428
ENST00000645284.1
ESPN
Intron
SCLC-I


chr1: 6455431
ENST00000645284.1
ESPN
Intron
SCLC-I


chr1: 6455441
ENST00000645284.1
ESPN
Intron
SCLC-I


chr1: 6455456
ENST00000645284.1
ESPN
Intron
SCLC-I


chr1: 6455459
ENST00000645284.1
ESPN
Intron
SCLC-I


chr1: 6455463
ENST00000645284.1
ESPN
Intron
SCLC-I


chr1: 6455469
ENST00000645284.1
ESPN
Intron
SCLC-I


chr1: 6455487
ENST00000645284.1
ESPN
Intron
SCLC-I


chr1: 6455494
ENST00000645284.1
ESPN
Intron
SCLC-I


chr1: 6455520
ENST00000645284.1
ESPN
Intron
SCLC-I


chr1: 6455535
ENST00000645284.1
ESPN
Intron
SCLC-I


chr1: 6455537
ENST00000645284.1
ESPN
Intron
SCLC-I


chr1: 7583360
ENST00000303635.12
CAMTA1
Intron
SCLC-I


chr1: 8395198
ENST00000337907.7
RERE
Intron
SCLC-I


chr1: 8395241
ENST00000337907.7
RERE
Intron
SCLC-I


chr1: 8395242
ENST00000337907.7
RERE
Intron
SCLC-I


chr1: 8395246
ENST00000337907.7
RERE
Intron
SCLC-I


chr1: 8395332
ENST00000337907.7
RERE
Intron
SCLC-I


chr1: 9688018
ENST00000377346.9
PIK3CD
Intron
SCLC-I


chr1: 9937029
ENST00000377223.6
LZIC
Intron
SCLC-I


chr1: 10638826
ENST00000377022.8
CASZ1
Exon
SCLC-I


chr1: 10638845
ENST00000377022.8
CASZ1
Exon
SCLC-I


chr1: 10638850
ENST00000377022.8
CASZ1
Exon
SCLC-I


chr1: 10638852
ENST00000377022.8
CASZ1
Exon
SCLC-I


chr1: 10638871
ENST00000377022.8
CASZ1
Exon
SCLC-I


chr1: 10638876
ENST00000377022.8
CASZ1
Exon
SCLC-I


chr1: 10638880
ENST00000377022.8
CASZ1
Exon
SCLC-I


chr1: 10638888
ENST00000377022.8
CASZ1
Exon
SCLC-I


chr1: 10638897
ENST00000377022.8
CASZ1
Exon
SCLC-I


chr1: 10638903
ENST00000377022.8
CASZ1
Exon
SCLC-I


chr1: 10638909
ENST00000377022.8
CASZ1
Exon
SCLC-I


chr1: 10638915
ENST00000377022.8
CASZ1
Exon
SCLC-I


chr1: 10638918
ENST00000377022.8
CASZ1
Exon
SCLC-I


chr1: 10638931
ENST00000377022.8
CASZ1
Exon
SCLC-I


chr1: 10638937
ENST00000377022.8
CASZ1
Exon
SCLC-I


chr1: 10638940
ENST00000377022.8
CASZ1
Exon
SCLC-I


chr1: 10638948
ENST00000377022.8
CASZ1
Exon
SCLC-I


chr1: 10638966
ENST00000377022.8
CASZ1
Exon
SCLC-I


chr1: 10716488
ENST00000377022.8
CASZ1
Intron
SCLC-I


chr1: 10716545
ENST00000377022.8
CASZ1
Intron
SCLC-I


chr1: 10716580
ENST00000377022.8
CASZ1
Intron
SCLC-I


chr1: 17691375
ENST00000361221.8
ARHGEF10L
Intron
SCLC-I


chr1: 17691405
ENST00000361221.8
ARHGEF10L
Intron
SCLC-I


chr1: 17691413
ENST00000361221.8
ARHGEF10L
Intron
SCLC-I


chr1: 17691414
ENST00000361221.8
ARHGEF10L
Intron
SCLC-I


chr1: 18951591
ENST00000455833.7
IFFO2
Intron
SCLC-I


chr1: 18951738
ENST00000455833.7
IFFO2
Intron
SCLC-I


chr1: 18951747
ENST00000455833.7
IFFO2
Intron
SCLC-I


chr1: 19257381
ENST00000479559.1
MRTO4
Promoter
SCLC-I


chr1: 20336464
ENST00000485375.6
VWA5B1
Exon
SCLC-I


chr1: 20336485
ENST00000485375.6
VWA5B1
Exon
SCLC-I


chr1: 20336496
ENST00000485375.6
VWA5B1
Intron
SCLC-I


chr1: 20726105
ENST00000460804.5
SH2D5
Intron
SCLC-I


chr1: 21293639
ENST00000415912.6
ECE1
Intron
SCLC-I


chr1: 26319030
ENST00000374213.3
CD52
Intron
SCLC-I


chr1: 26319037
ENST00000374213.3
CD52
Intron
SCLC-I


chr1: 26319047
ENST00000374213.3
CD52
Intron
SCLC-I


chr1: 26319074
ENST00000374213.3
CD52
Intron
SCLC-I


chr1: 26319169
ENST00000374213.3
CD52
Intron
SCLC-I


chr1: 26319170
ENST00000374213.3
CD52
Intron
SCLC-I


chr1: 27349314
ENST00000496001.5
SYTL1
Promoter
SCLC-I


chr1: 27349516
ENST00000485269.1
SYTL1
Promoter
SCLC-I


chr1: 27349765
ENST00000490170.5
SYTL1
Exon
SCLC-I


chr1: 27361001
ENST00000357582.3
MAP3K6
Exon
SCLC-I


chr1: 27361110
ENST00000357582.3
MAP3K6
Intron
SCLC-I


chr1: 43348635
ENST00000638732.1
MPL
Intron
SCLC-I


chr1: 43348644
ENST00000638732.1
MPL
Intron
SCLC-I


chr1: 43348678
ENST00000638732.1
MPL
Intron
SCLC-I


chr1: 43348748
ENST00000638732.1
MPL
Intron
SCLC-I


chr1: 43348752
ENST00000638732.1
MPL
Intron
SCLC-I


chr1: 43348792
ENST00000638732.1
MPL
Intron
SCLC-I


chr1: 43348803
ENST00000638732.1
MPL
Intron
SCLC-I


chr1: 43348811
ENST00000638732.1
MPL
Intron
SCLC-I


chr1: 43348817
ENST00000638732.1
MPL
Intron
SCLC-I


chr1: 87132531
ENST00000370548.3
LINC01140
Intron
SCLC-I


chr1: 112621401
ENST00000485542.5
CAPZA1
Intron
SCLC-I


chr1: 112621449
ENST00000485542.5
CAPZA1
Intron
SCLC-I


chr1: 117151249
ENST00000359008.8
VTCN1
Intron
SCLC-I


chr1: 118990162
ENST00000207157.7
TBX15
Promoter
SCLC-I


chr1: 201648427
ENST00000367302.5
NAV1
Intron
SCLC-I


chr1: 201648899
ENST00000367296.8
NAV1
Exon
SCLC-I


chr1: 201648902
ENST00000367296.8
NAV1
Exon
SCLC-I


chr1: 201648907
ENST00000367296.8
NAV1
Exon
SCLC-I


chr1: 201648911
ENST00000367296.8
NAV1
Exon
SCLC-I


chr1: 201648924
ENST00000367296.8
NAV1
Exon
SCLC-I


chr1: 201649103
ENST00000367296.8
NAV1
Exon
SCLC-I


chr1: 201649526
ENST00000367302.5
NAV1
Intron
SCLC-I


chr1: 201649545
ENST00000367302.5
NAV1
Intron
SCLC-I


chr1: 201649568
ENST00000367302.5
NAV1
Intron
SCLC-I


chr1: 201649569
ENST00000367302.5
NAV1
Intron
SCLC-I


chr1: 201649603
ENST00000367302.5
NAV1
Intron
SCLC-I


chr1: 201649604
ENST00000367302.5
NAV1
Intron
SCLC-I


chr1: 201649642
ENST00000367302.5
NAV1
Intron
SCLC-I


chr1: 201649650
ENST00000367302.5
NAV1
Intron
SCLC-I


chr1: 201650616
ENST00000367302.5
NAV1
Intron
SCLC-I


chr1: 204194977
ENST00000367194.5
KISS1
Intron
SCLC-I


chr1: 204379054
ENST00000443515.1
NA
Intron
SCLC-I


chr1: 212981403
ENST00000366966.6
VASH2
Intron
SCLC-I


chr1: 212981607
ENST00000366966.6
VASH2
Intron
SCLC-I


chr1: 226712073
ENST00000272117.7
ITPKB
Intron
SCLC-I


chr10: 6204251
ENST00000379789.8
PFKFB3
Intron
SCLC-I


chr10: 11180532
ENST00000633200.1
CELF2
Intron
SCLC-I


chr10: 21494147
ENST00000658000.1
MIR1915HG
Exon
SCLC-I


chr10: 21494162
ENST00000658000.1
MIR1915HG
Exon
SCLC-I


chr10: 21494163
ENST00000658000.1
MIR1915HG
Exon
SCLC-I


chr10: 48655690
ENST00000460425.1
ARHGAP22
UTR5
SCLC-I


chr10: 48655692
ENST00000460425.1
ARHGAP22
UTR5
SCLC-I


chr10: 48655695
ENST00000460425.1
ARHGAP22
UTR5
SCLC-I


chr10: 79261299
ENST00000334512.10
ZMIZ1
Intron
SCLC-I


chr10: 79266615
ENST00000334512.10
ZMIZ1
Intron
SCLC-I


chr10: 103664060
ENST00000369774.8
SH3PXD2A
Intron
SCLC-I


chr10: 103664157
ENST00000369774.8
SH3PXD2A
Intron
SCLC-I


chr10: 110072448
ENST00000468251.5
ADD3
Intron
SCLC-I


chr10: 127738809
ENST00000388920.5
FOXI2
Exon
SCLC-I


chr10: 127738825
ENST00000388920.5
FOXI2
Exon
SCLC-I


chr10: 127738831
ENST00000388920.5
FOXI2
Exon
SCLC-I


chr10: 127738832
ENST00000388920.5
FOXI2
Exon
SCLC-I


chr10: 127738838
ENST00000388920.5
FOXI2
Exon
SCLC-I


chr10: 127738839
ENST00000388920.5
FOXI2
Exon
SCLC-I


chr10: 127738845
ENST00000388920.5
FOXI2
Exon
SCLC-I


chr11: 1310191
ENST00000530506.5
TOLLIP
Promoter
SCLC-I


chr11: 1310193
ENST00000530506.5
TOLLIP
Promoter
SCLC-I


chr11: 1310196
ENST00000530506.5
TOLLIP
Promoter
SCLC-I


chr11: 1310201
ENST00000530506.5
TOLLIP
Promoter
SCLC-I


chr11: 1310212
ENST00000530506.5
TOLLIP
Promoter
SCLC-I


chr11: 1310227
ENST00000530506.5
TOLLIP
Promoter
SCLC-I


chr11: 2807477
ENST00000155840.11
KCNQ1
Intron
SCLC-I


chr11: 2807560
ENST00000155840.11
KCNQ1
Intron
SCLC-I


chr11: 44308565
ENST00000652299.1
ALX4
Intron
SCLC-I


chr11: 62602888
ENST00000460939.5
EML3
Exon
SCLC-I


chr11: 64082224
ENST00000545464.5
MACROD1
Intron
SCLC-I


chr11: 64206312
ENST00000544997.5
FERMT3
Promoter
SCLC-I


chr11: 64206975
ENST00000544997.5
FERMT3
Intron
SCLC-I


chr11: 64206999
ENST00000544997.5
FERMT3
Intron
SCLC-I


chr11: 64207068
ENST00000544997.5
FERMT3
Intron
SCLC-I


chr11: 65640874
ENST00000394224.3
SIPA1
Exon
SCLC-I


chr11: 65640888
ENST00000394224.3
SIPA1
Exon
SCLC-I


chr11: 70424335
ENST00000346329.7
CTTN
Intron
SCLC-I


chr11: 70424342
ENST00000346329.7
CTTN
Intron
SCLC-I


chr11: 111414539
ENST00000525890.1
NA
Intron
SCLC-I


chr11: 113243216
ENST00000620046.4
NCAM1
Intron
SCLC-I


chr11: 117992014
ENST00000526544.5
IL10RA
Intron
SCLC-I


chr11: 118088224
ENST00000519126.1
TMPRSS4
Intron
SCLC-I


chr11: 118088319
ENST00000519126.1
TMPRSS4
Intron
SCLC-I


chr11: 118088507
ENST00000519126.1
TMPRSS4
Intron
SCLC-I


chr12: 1797594
ENST00000541444.5
CACNA2D4
Exon
SCLC-I


chr12: 1834565
ENST00000444595.6
CACNA2D4
Intron
SCLC-I


chr12: 1881455
ENST00000382722.10
CACNA2D4
Intron
SCLC-I


chr12: 1921064
ENST00000544163.1
NA
Intron
SCLC-I


chr12: 1921078
ENST00000544163.1
NA
Intron
SCLC-I


chr12: 1921094
ENST00000544163.1
NA
Intron
SCLC-I


chr12: 2100317
ENST00000543114.1
CACNA1C
Intron
SCLC-I


chr12: 2100392
ENST00000543114.1
CACNA1C
Intron
SCLC-I


chr12: 2387345
ENST00000327702.12
CACNA1C
Intron
SCLC-I


chr12: 2387357
ENST00000327702.12
CACNA1C
Intron
SCLC-I


chr12: 2387399
ENST00000327702.12
CACNA1C
Intron
SCLC-I


chr12: 2412248
ENST00000327702.12
CACNA1C
Intron
SCLC-I


chr12: 2414570
ENST00000327702.12
CACNA1C
Intron
SCLC-I


chr12: 2578542
ENST00000327702.12
CACNA1C
Intron
SCLC-I


chr12: 2578571
ENST00000327702.12
CACNA1C
Intron
SCLC-I


chr12: 2578612
ENST00000327702.12
CACNA1C
Intron
SCLC-I


chr12: 2660687
ENST00000327702.12
CACNA1C
Intron
SCLC-I


chr12: 2660692
ENST00000327702.12
CACNA1C
Intron
SCLC-I


chr12: 2660693
ENST00000327702.12
CACNA1C
Intron
SCLC-I


chr12: 2660716
ENST00000327702.12
CACNA1C
Intron
SCLC-I


chr12: 6951500
ENST00000534900.5
PTPN6
Intron
SCLC-I


chr12: 6952413
ENST00000543744.1
PTPN6
Exon
SCLC-I


chr12: 6952423
ENST00000543744.1
PTPN6
Exon
SCLC-I


chr12: 6959128
ENST00000399448.5
PTPN6
Intron
SCLC-I


chr12: 6963341
ENST00000384980.3
MIR200C
Promoter
SCLC-I


chr12: 52250263
ENST00000548657.5
KRT7
Intron
SCLC-I


chr12: 52250331
ENST00000548657.5
KRT7
Intron
SCLC-I


chr12: 52250333
ENST00000548657.5
KRT7
Intron
SCLC-I


chr12: 52250345
ENST00000548657.5
KRT7
Intron
SCLC-I


chr12: 52250364
ENST00000548657.5
KRT7
Intron
SCLC-I


chr12: 52250382
ENST00000548657.5
KRT7
Intron
SCLC-I


chr12: 52250393
ENST00000548657.5
KRT7
Intron
SCLC-I


chr12: 52258477
ENST00000553310.6
KRT86
Intron
SCLC-I


chr12: 52258484
ENST00000553310.6
KRT86
Intron
SCLC-I


chr12: 52258491
ENST00000553310.6
KRT86
Intron
SCLC-I


chr12: 52258508
ENST00000553310.6
KRT86
Intron
SCLC-I


chr12: 52258510
ENST00000553310.6
KRT86
Intron
SCLC-I


chr12: 52258517
ENST00000553310.6
KRT86
Intron
SCLC-I


chr12: 52258526
ENST00000553310.6
KRT86
Intron
SCLC-I


chr12: 52258534
ENST00000553310.6
KRT86
Intron
SCLC-I


chr12: 52258558
ENST00000553310.6
KRT86
Intron
SCLC-I


chr12: 52258564
ENST00000553310.6
KRT86
Intron
SCLC-I


chr12: 52258573
ENST00000553310.6
KRT86
Intron
SCLC-I


chr12: 52258577
ENST00000553310.6
KRT86
Intron
SCLC-I


chr12: 57225160
ENST00000349394.6
NXPH4
Exon
SCLC-I


chr12: 57225395
ENST00000349394.6
NXPH4
Exon
SCLC-I


chr12: 57235345
ENST00000554503.5
NDUFA4L2
Exon
SCLC-I


chr12: 57726072
ENST00000257897.7
AGAP2
Exon
SCLC-I


chr12: 57726090
ENST00000257897.7
AGAP2
Exon
SCLC-I


chr12: 57726567
ENST00000257897.7
AGAP2
Exon
SCLC-I


chr12: 57726572
ENST00000257897.7
AGAP2
Exon
SCLC-I


chr12: 57726576
ENST00000257897.7
AGAP2
Exon
SCLC-I


chr12: 57726578
ENST00000257897.7
AGAP2
Exon
SCLC-I


chr12: 57726580
ENST00000257897.7
AGAP2
Exon
SCLC-I


chr12: 57726587
ENST00000257897.7
AGAP2
Exon
SCLC-I


chr12: 57726593
ENST00000257897.7
AGAP2
Exon
SCLC-I


chr12: 57726596
ENST00000257897.7
AGAP2
Exon
SCLC-I


chr12: 57726604
ENST00000257897.7
AGAP2
Exon
SCLC-I


chr12: 57726607
ENST00000257897.7
AGAP2
Exon
SCLC-I


chr12: 57726610
ENST00000257897.7
AGAP2
Exon
SCLC-I


chr12: 57726621
ENST00000257897.7
AGAP2
Exon
SCLC-I


chr12: 57726626
ENST00000257897.7
AGAP2
Exon
SCLC-I


chr12: 57726639
ENST00000257897.7
AGAP2
Exon
SCLC-I


chr12: 57726648
ENST00000257897.7
AGAP2
Exon
SCLC-I


chr12: 57726650
ENST00000257897.7
AGAP2
Exon
SCLC-I


chr12: 57726657
ENST00000257897.7
AGAP2
Exon
SCLC-I


chr12: 57726666
ENST00000257897.7
AGAP2
Exon
SCLC-I


chr12: 57726668
ENST00000257897.7
AGAP2
Exon
SCLC-I


chr12: 57726674
ENST00000257897.7
AGAP2
Exon
SCLC-I


chr12: 57726684
ENST00000257897.7
AGAP2
Exon
SCLC-I


chr12: 57726692
ENST00000257897.7
AGAP2
Exon
SCLC-I


chr12: 57726710
ENST00000257897.7
AGAP2
Exon
SCLC-I


chr12: 57726713
ENST00000257897.7
AGAP2
Exon
SCLC-I


chr12: 57726736
ENST00000257897.7
AGAP2
Exon
SCLC-I


chr12: 57726740
ENST00000257897.7
AGAP2
Exon
SCLC-I


chr12: 57726750
ENST00000257897.7
AGAP2
Exon
SCLC-I


chr12: 57726753
ENST00000257897.7
AGAP2
Exon
SCLC-I


chr12: 57726757
ENST00000257897.7
AGAP2
Exon
SCLC-I


chr12: 57726767
ENST00000257897.7
AGAP2
Exon
SCLC-I


chr12: 57726772
ENST00000257897.7
AGAP2
Exon
SCLC-I


chr12: 57726782
ENST00000257897.7
AGAP2
Exon
SCLC-I


chr12: 57726786
ENST00000257897.7
AGAP2
Exon
SCLC-I


chr12: 57726788
ENST00000257897.7
AGAP2
Exon
SCLC-I


chr12: 57726791
ENST00000257897.7
AGAP2
Exon
SCLC-I


chr12: 57726803
ENST00000542466.2
AGAP2-AS1
Intron
SCLC-I


chr12: 57726809
ENST00000542466.2
AGAP2-AS1
Intron
SCLC-I


chr12: 57726815
ENST00000542466.2
AGAP2-AS1
Intron
SCLC-I


chr12: 57726821
ENST00000542466.2
AGAP2-AS1
Intron
SCLC-I


chr12: 57726823
ENST00000542466.2
AGAP2-AS1
Intron
SCLC-I


chr12: 57726825
ENST00000542466.2
AGAP2-AS1
Intron
SCLC-I


chr12: 57726836
ENST00000542466.2
AGAP2-AS1
Intron
SCLC-I


chr12: 57736329
ENST00000257897.7
AGAP2
Intron
SCLC-I


chr12: 57737351
ENST00000257897.7
AGAP2
Intron
SCLC-I


chr12: 57737630
ENST00000257897.7
AGAP2
Intron
SCLC-I


chr12: 57738134
ENST00000257897.7
AGAP2
Intron
SCLC-I


chr12: 57738397
ENST00000257897.7
AGAP2
Intron
SCLC-I


chr12: 80708706
ENST00000228641.4
MYF6
Intron
SCLC-I


chr12: 80708732
ENST00000228641.4
MYF6
Intron
SCLC-I


chr12: 124463522
ENST00000448008.1
NCOR2
Intron
SCLC-I


chr12: 128939360
ENST00000281703.11
GLT1D1
Intron
SCLC-I


chr13: 25973246
ENST00000381655.7
ATP8A2
Intron
SCLC-I


chr13: 48319241
ENST00000467505.5
RB1
Intron
SCLC-I


chr13: 48319243
ENST00000467505.5
RB1
Intron
SCLC-I


chr13: 48319263
ENST00000467505.5
RB1
Intron
SCLC-I


chr13: 48319281
ENST00000467505.5
RB1
Intron
SCLC-I


chr13: 48319291
ENST00000467505.5
RB1
Intron
SCLC-I


chr13: 48319306
ENST00000467505.5
RB1
Intron
SCLC-I


chr13: 50132310
ENST00000476738.5
DLEU1
Intron
SCLC-I


chr13: 50133486
ENST00000476738.5
DLEU1
Intron
SCLC-I


chr13: 50133529
ENST00000476738.5
DLEU1
Intron
SCLC-I


chr13: 50133537
ENST00000476738.5
DLEU1
Intron
SCLC-I


chr13: 50133563
ENST00000476738.5
DLEU1
Intron
SCLC-I


chr13: 50133576
ENST00000476738.5
DLEU1
Intron
SCLC-I


chr13: 50133608
ENST00000476738.5
DLEU1
Intron
SCLC-I


chr13: 78607453
ENST00000560209.6
OBI1-AS1
Intron
SCLC-I


chr13: 78607812
ENST00000560209.6
OBI1-AS1
Intron
SCLC-I


chr14: 36579935
ENST00000634305.1
NA
Intron
SCLC-I


chr14: 37602183
ENST00000556845.1
TTC6
Intron
SCLC-I


chr14: 38256100
ENST00000655453.1
NA
Promoter
SCLC-I


chr14: 38256107
ENST00000655453.1
NA
Promoter
SCLC-I


chr14: 60515473
ENST00000557618.1
NA
Intron
SCLC-I


chr14: 60515555
ENST00000557618.1
NA
Intron
SCLC-I


chr14: 60515579
ENST00000557618.1
NA
Intron
SCLC-I


chr14: 60515651
ENST00000557618.1
NA
Intron
SCLC-I


chr14: 60515654
ENST00000557618.1
NA
Intron
SCLC-I


chr14: 60515656
ENST00000557618.1
NA
Intron
SCLC-I


chr14: 60515669
ENST00000557618.1
NA
Intron
SCLC-I


chr14: 60515671
ENST00000557618.1
NA
Intron
SCLC-I


chr14: 60515691
ENST00000557618.1
NA
Intron
SCLC-I


chr14: 60515705
ENST00000557618.1
NA
Intron
SCLC-I


chr14: 65287668
ENST00000555736.1
NA
Intron
SCLC-I


chr14: 65287696
ENST00000555736.1
NA
Intron
SCLC-I


chr14: 65287718
ENST00000555736.1
NA
Intron
SCLC-I


chr14: 65287767
ENST00000555736.1
NA
Intron
SCLC-I


chr14: 65287768
ENST00000555736.1
NA
Intron
SCLC-I


chr14: 69944274
ENST00000555917.1
SMOC1
Intron
SCLC-I


chr14: 74922831
ENST00000555834.5
RPS6KL1
Intron
SCLC-I


chr14: 74922839
ENST00000555834.5
RPS6KL1
Intron
SCLC-I


chr14: 74922865
ENST00000555834.5
RPS6KL1
Intron
SCLC-I


chr14: 74922893
ENST00000555834.5
RPS6KL1
Intron
SCLC-I


chr14: 74922915
ENST00000555834.5
RPS6KL1
Intron
SCLC-I


chr14: 74922930
ENST00000555834.5
RPS6KL1
Intron
SCLC-I


chr14: 77025612
ENST00000238647.5
IRF2BPL
Exon
SCLC-I


chr14: 77025619
ENST00000238647.5
IRF2BPL
Exon
SCLC-I


chr14: 77025636
ENST00000238647.5
IRF2BPL
Exon
SCLC-I


chr14: 77025685
ENST00000238647.5
IRF2BPL
Exon
SCLC-I


chr14: 77025829
ENST00000238647.5
IRF2BPL
Exon
SCLC-I


chr14: 77025834
ENST00000238647.5
IRF2BPL
Exon
SCLC-I


chr14: 77025840
ENST00000238647.5
IRF2BPL
Exon
SCLC-I


chr14: 77025857
ENST00000238647.5
IRF2BPL
Exon
SCLC-I


chr14: 77026043
ENST00000238647.5
IRF2BPL
Exon
SCLC-I


chr14: 77026046
ENST00000238647.5
IRF2BPL
Exon
SCLC-I


chr14: 77026047
ENST00000238647.5
IRF2BPL
Exon
SCLC-I


chr14: 77026070
ENST00000238647.5
IRF2BPL
Exon
SCLC-I


chr14: 77026080
ENST00000238647.5
IRF2BPL
Exon
SCLC-I


chr14: 77026109
ENST00000238647.5
IRF2BPL
Exon
SCLC-I


chr14: 77026122
ENST00000238647.5
IRF2BPL
Exon
SCLC-I


chr14: 77026124
ENST00000238647.5
IRF2BPL
Exon
SCLC-I


chr14: 77026130
ENST00000238647.5
IRF2BPL
Exon
SCLC-I


chr14: 77026236
ENST00000238647.5
IRF2BPL
Exon
SCLC-I


chr14: 77026245
ENST00000238647.5
IRF2BPL
Exon
SCLC-I


chr14: 77026247
ENST00000238647.5
IRF2BPL
Exon
SCLC-I


chr14: 77026290
ENST00000238647.5
IRF2BPL
Exon
SCLC-I


chr14: 77026317
ENST00000238647.5
IRF2BPL
Exon
SCLC-I


chr14: 77026323
ENST00000238647.5
IRF2BPL
Exon
SCLC-I


chr14: 77026441
ENST00000238647.5
IRF2BPL
Exon
SCLC-I


chr14: 77026445
ENST00000238647.5
IRF2BPL
Exon
SCLC-I


chr14: 77026559
ENST00000238647.5
IRF2BPL
Exon
SCLC-I


chr14: 77026571
ENST00000238647.5
IRF2BPL
Exon
SCLC-I


chr14: 77026650
ENST00000238647.5
IRF2BPL
Exon
SCLC-I


chr14: 77026837
ENST00000238647.5
IRF2BPL
Exon
SCLC-I


chr14: 77026840
ENST00000238647.5
IRF2BPL
Exon
SCLC-I


chr14: 91375740
ENST00000389857.11
CCDC88C
Intron
SCLC-I


chr14: 92687670
ENST00000556418.1
RIN3
Exon
SCLC-I


chr14: 92687692
ENST00000556418.1
RIN3
Exon
SCLC-I


chr14: 92687699
ENST00000556418.1
RIN3
Exon
SCLC-I


chr14: 92687725
ENST00000556418.1
RIN3
Exon
SCLC-I


chr14: 92687758
ENST00000556418.1
RIN3
Exon
SCLC-I


chr14: 92687767
ENST00000556418.1
RIN3
Exon
SCLC-I


chr14: 92687795
ENST00000556418.1
RIN3
Exon
SCLC-I


chr14: 95191817
ENST00000556416.1
CLMN
Exon
SCLC-I


chr14: 95714410
ENST00000547644.6
LOC107984703
Intron
SCLC-I


chr14: 104103193
ENST00000551170.1
ASPG
Intron
SCLC-I


chr14: 105060914
ENST00000546679.1
GPR132
Intron
SCLC-I


chr15: 34018462
ENST00000560035.1
CHRM5
Intron
SCLC-I


chr15: 42608310
ENST00000563872.5
STARD9
Intron
SCLC-I


chr15: 45650342
ENST00000564080.1
SQOR
Intron
SCLC-I


chr15: 45650351
ENST00000564080.1
SQOR
Intron
SCLC-I


chr15: 47985845
ENST00000664705.1
NA
Intron
SCLC-I


chr15: 47985925
ENST00000664705.1
NA
Intron
SCLC-I


chr15: 65028370
ENST00000220058.9
MTFMT
Intron
SCLC-I


chr15: 65028409
ENST00000220058.9
MTFMT
Intron
SCLC-I


chr15: 92623668
ENST00000553393.5
FAM174B
Intron
SCLC-I


chr15: 93041663
ENST00000329082.11
RGMA
Exon
SCLC-I


chr16: 3027967
ENST00000572240.5
BICDL2
Exon
SCLC-I


chr16: 20349066
ENST00000396134.6
UMOD
Exon
SCLC-I


chr16: 20349093
ENST00000396134.6
UMOD
Exon
SCLC-I


chr16: 30751128
ENST00000569762.1
PHKG2
Exon
SCLC-I


chr16: 54288396
ENST00000637770.1
NA
Intron
SCLC-I


chr16: 54288536
ENST00000637770.1
NA
Intron
SCLC-I


chr16: 54288547
ENST00000637770.1
NA
Intron
SCLC-I


chr16: 57894225
ENST00000565942.1
CNGB1
Intron
SCLC-I


chr16: 67165147
ENST00000518753.5
HSF4
Intron
SCLC-I


chr16: 67165148
ENST00000518753.5
HSF4
Intron
SCLC-I


chr16: 67165753
ENST00000519224.5
HSF4
Promoter
SCLC-I


chr16: 67284771
ENST00000393966.1
PLEKHG4
Intron
SCLC-I


chr16: 67441430
ENST00000568620.5
ATP6V0D1
Exon
SCLC-I


chr16: 67653815
ENST00000334583.11
CARMIL2
Intron
SCLC-I


chr16: 67653842
ENST00000334583.11
CARMIL2
Intron
SCLC-I


chr16: 67653852
ENST00000334583.11
CARMIL2
Intron
SCLC-I


chr16: 68235387
ENST00000473183.7
ESRP2
Intron
SCLC-I


chr16: 68235392
ENST00000473183.7
ESRP2
Intron
SCLC-I


chr16: 68235401
ENST00000473183.7
ESRP2
Intron
SCLC-I


chr16: 68235462
ENST00000473183.7
ESRP2
Intron
SCLC-I


chr16: 68235464
ENST00000473183.7
ESRP2
Intron
SCLC-I


chr16: 68235479
ENST00000473183.7
ESRP2
Intron
SCLC-I


chr16: 68235485
ENST00000473183.7
ESRP2
Intron
SCLC-I


chr16: 68235487
ENST00000473183.7
ESRP2
Intron
SCLC-I


chr16: 68235494
ENST00000473183.7
ESRP2
Intron
SCLC-I


chr16: 68235527
ENST00000473183.7
ESRP2
Intron
SCLC-I


chr16: 68235695
ENST00000562567.6
ESRP2
Promoter
SCLC-I


chr16: 85220415
ENST00000637419.1
GSE1
Intron
SCLC-I


chr16: 85282587
ENST00000637419.1
GSE1
Intron
SCLC-I


chr16: 85382138
ENST00000637419.1
GSE1
Intron
SCLC-I


chr16: 85449451
ENST00000637419.1
GSE1
Intron
SCLC-I


chr16: 85449457
ENST00000637419.1
GSE1
Intron
SCLC-I


chr16: 85452157
ENST00000637419.1
GSE1
Intron
SCLC-I


chr16: 85452179
ENST00000637419.1
GSE1
Intron
SCLC-I


chr16: 85452187
ENST00000637419.1
GSE1
Intron
SCLC-I


chr16: 85452198
ENST00000637419.1
GSE1
Intron
SCLC-I


chr16: 85452271
ENST00000637419.1
GSE1
Intron
SCLC-I


chr16: 85452273
ENST00000637419.1
GSE1
Intron
SCLC-I


chr16: 85485649
ENST00000637419.1
GSE1
Intron
SCLC-I


chr16: 85594161
ENST00000637419.1
GSE1
Intron
SCLC-I


chr16: 88505436
ENST00000563351.5
ZFPM1
Intron
SCLC-I


chr16: 88505689
ENST00000563351.5
ZFPM1
Intron
SCLC-I


chr16: 88505707
ENST00000563351.5
ZFPM1
Intron
SCLC-I


chr16: 88703333
ENST00000567844.1
RNF166
Intron
SCLC-I


chr16: 88703359
ENST00000567844.1
RNF166
Intron
SCLC-I


chr17: 4600012
ENST00000338859.8
SMTNL2
Intron
SCLC-I


chr17: 4600024
ENST00000338859.8
SMTNL2
Intron
SCLC-I


chr17: 4600031
ENST00000338859.8
SMTNL2
Intron
SCLC-I


chr17: 4600044
ENST00000338859.8
SMTNL2
Intron
SCLC-I


chr17: 8799394
ENST00000329805.6
MFSD6L
Promoter
SCLC-I


chr17: 8799405
ENST00000329805.6
MFSD6L
Promoter
SCLC-I


chr17: 8799413
ENST00000329805.6
MFSD6L
Promoter
SCLC-I


chr17: 8799419
ENST00000329805.6
MFSD6L
Promoter
SCLC-I


chr17: 8799421
ENST00000329805.6
MFSD6L
Promoter
SCLC-I


chr17: 8799434
ENST00000329805.6
MFSD6L
Promoter
SCLC-I


chr17: 34637675
ENST00000321639.7
TMEM132E
Exon
SCLC-I


chr17: 34637684
ENST00000321639.7
TMEM132E
Exon
SCLC-I


chr17: 34637686
ENST00000321639.7
TMEM132E
Exon
SCLC-I


chr17: 38561771
ENST00000617146.5
SRCIN1
Exon
SCLC-I


chr17: 38561774
ENST00000617146.5
SRCIN1
Exon
SCLC-I


chr17: 38561777
ENST00000617146.5
SRCIN1
Exon
SCLC-I


chr17: 38561784
ENST00000617146.5
SRCIN1
Exon
SCLC-I


chr17: 38561847
ENST00000617146.5
SRCIN1
Exon
SCLC-I


chr17: 38561862
ENST00000617146.5
SRCIN1
Exon
SCLC-I


chr17: 45241394
ENST00000587856.1
FMNL1
Exon
SCLC-I


chr17: 45241459
ENST00000587856.1
FMNL1
Exon
SCLC-I


chr17: 45241470
ENST00000587856.1
FMNL1
Exon
SCLC-I


chr17: 45241527
ENST00000587856.1
FMNL1
Exon
SCLC-I


chr17: 45247010
ENST00000420431.2
NA
Intron
SCLC-I


chr17: 48838028
ENST00000508679.5
CALCOCO2
Intron
SCLC-I


chr17: 48838036
ENST00000508679.5
CALCOCO2
Intron
SCLC-I


chr17: 58487554
ENST00000323777.8
HSF5
Intron
SCLC-I


chr17: 58487572
ENST00000323777.8
HSF5
Intron
SCLC-I


chr17: 58487581
ENST00000323777.8
HSF5
Intron
SCLC-I


chr17: 58488117
ENST00000323777.8
HSF5
Exon
SCLC-I


chr17: 58488136
ENST00000323777.8
HSF5
Exon
SCLC-I


chr17: 58488137
ENST00000323777.8
HSF5
Exon
SCLC-I


chr17: 58488151
ENST00000323777.8
HSF5
Exon
SCLC-I


chr17: 58488172
ENST00000323777.8
HSF5
Exon
SCLC-I


chr17: 58488175
ENST00000323777.8
HSF5
Exon
SCLC-I


chr17: 58488183
ENST00000323777.8
HSF5
Exon
SCLC-I


chr17: 58488198
ENST00000323777.8
HSF5
Exon
SCLC-I


chr17: 58488200
ENST00000323777.8
HSF5
Exon
SCLC-I


chr17: 58488201
ENST00000323777.8
HSF5
Exon
SCLC-I


chr17: 58488216
ENST00000323777.8
HSF5
Exon
SCLC-I


chr17: 58488280
ENST00000323777.8
HSF5
Exon
SCLC-I


chr17: 58488281
ENST00000323777.8
HSF5
Exon
SCLC-I


chr17: 63420277
ENST00000583552.1
NA
Intron
SCLC-I


chr17: 63420295
ENST00000583552.1
NA
Intron
SCLC-I


chr17: 63420387
ENST00000583552.1
NA
Intron
SCLC-I


chr17: 63420388
ENST00000583552.1
NA
Intron
SCLC-I


chr17: 72116717
ENST00000529667.1
SOX9-AS1
Intron
SCLC-I


chr17: 72116724
ENST00000529667.1
SOX9-AS1
Intron
SCLC-I


chr17: 72589138
ENST00000648088.1
LINC00673
Intron
SCLC-I


chr17: 72589198
ENST00000648088.1
LINC00673
Intron
SCLC-I


chr17: 75012406
ENST00000584208.5
MRPL58
Promoter
SCLC-I


chr17: 75141194
ENST00000356033.8
JPT1
Intron
SCLC-I


chr17: 75141237
ENST00000356033.8
JPT1
Intron
SCLC-I


chr17: 77453652
ENST00000588575.1
SEPTIN9
Intron
SCLC-I


chr17: 77453692
ENST00000588575.1
SEPTIN9
Intron
SCLC-I


chr17: 81135920
ENST00000326724.9
AATK
Intron
SCLC-I


chr17: 81136020
ENST00000326724.9
AATK
Intron
SCLC-I


chr17: 81136037
ENST00000326724.9
AATK
Intron
SCLC-I


chr17: 81136041
ENST00000326724.9
AATK
Intron
SCLC-I


chr17: 81136066
ENST00000326724.9
AATK
Intron
SCLC-I


chr17: 81136085
ENST00000326724.9
AATK
Intron
SCLC-I


chr17: 81136104
ENST00000326724.9
AATK
Intron
SCLC-I


chr17: 81136111
ENST00000326724.9
AATK
Intron
SCLC-I


chr19: 1071166
ENST00000591293.2
ARHGAP45
Intron
SCLC-I


chr19: 1071186
ENST00000591293.2
ARHGAP45
Intron
SCLC-I


chr19: 1083008
ENST00000586378.5
ARHGAP45
Exon
SCLC-I


chr19: 2274694
ENST00000621615.1
SPPL2B
Intron
SCLC-I


chr19: 2274698
ENST00000621615.1
SPPL2B
Intron
SCLC-I


chr19: 2274700
ENST00000621615.1
SPPL2B
Intron
SCLC-I


chr19: 2274710
ENST00000621615.1
SPPL2B
Intron
SCLC-I


chr19: 2274754
ENST00000621615.1
SPPL2B
Intron
SCLC-I


chr19: 3179282
ENST00000246115.5
S1PR4
Exon
SCLC-I


chr19: 3179291
ENST00000246115.5
S1PR4
Exon
SCLC-I


chr19: 3179367
ENST00000246115.5
S1PR4
Exon
SCLC-I


chr19: 5046476
ENST00000611640.4
KDM4B
Intron
SCLC-I


chr19: 5046532
ENST00000611640.4
KDM4B
Intron
SCLC-I


chr19: 5046687
ENST00000611640.4
KDM4B
Intron
SCLC-I


chr19: 5046728
ENST00000611640.4
KDM4B
Intron
SCLC-I


chr19: 8526066
ENST00000644032.2
MYO1F
Intron
SCLC-I


chr19: 8526099
ENST00000644032.2
MYO1F
Intron
SCLC-I


chr19: 9883533
ENST00000264833.8
OLFM2
Intron
SCLC-I


chr19: 9883534
ENST00000264833.8
OLFM2
Intron
SCLC-I


chr19: 9883653
ENST00000264833.8
OLFM2
Intron
SCLC-I


chr19: 9883659
ENST00000264833.8
OLFM2
Intron
SCLC-I


chr19: 9883675
ENST00000264833.8
OLFM2
Intron
SCLC-I


chr19: 10334198
ENST00000612689.1
NA
Exon
SCLC-I


chr19: 10334209
ENST00000612689.1
NA
Exon
SCLC-I


chr19: 10334241
ENST00000612689.1
NA
Exon
SCLC-I


chr19: 10334247
ENST00000612689.1
NA
Exon
SCLC-I


chr19: 10334670
ENST00000612689.1
NA
Exon
SCLC-I


chr19: 10334678
ENST00000612689.1
NA
Exon
SCLC-I


chr19: 10334698
ENST00000612689.1
NA
Exon
SCLC-I


chr19: 10334720
ENST00000612689.1
NA
Exon
SCLC-I


chr19: 10334744
ENST00000612689.1
NA
Exon
SCLC-I


chr19: 10625535
ENST00000590382.5
SLC44A2
Intron
SCLC-I


chr19: 10625547
ENST00000590382.5
SLC44A2
Intron
SCLC-I


chr19: 10625549
ENST00000590382.5
SLC44A2
Intron
SCLC-I


chr19: 10625581
ENST00000590382.5
SLC44A2
Intron
SCLC-I


chr19: 10625589
ENST00000590382.5
SLC44A2
Intron
SCLC-I


chr19: 10625607
ENST00000590382.5
SLC44A2
Intron
SCLC-I


chr19: 10625611
ENST00000590382.5
SLC44A2
Intron
SCLC-I


chr19: 10625613
ENST00000590382.5
SLC44A2
Intron
SCLC-I


chr19: 10625614
ENST00000590382.5
SLC44A2
Intron
SCLC-I


chr19: 10625623
ENST00000590382.5
SLC44A2
Intron
SCLC-I


chr19: 10625624
ENST00000590382.5
SLC44A2
Intron
SCLC-I


chr19: 10625642
ENST00000590382.5
SLC44A2
Intron
SCLC-I


chr19: 10625646
ENST00000590382.5
SLC44A2
Intron
SCLC-I


chr19: 10625647
ENST00000590382.5
SLC44A2
Intron
SCLC-I


chr19: 10625669
ENST00000590382.5
SLC44A2
Intron
SCLC-I


chr19: 10625670
ENST00000590382.5
SLC44A2
Intron
SCLC-I


chr19: 10625679
ENST00000590382.5
SLC44A2
Intron
SCLC-I


chr19: 10625680
ENST00000590382.5
SLC44A2
Intron
SCLC-I


chr19: 10625686
ENST00000590382.5
SLC44A2
Intron
SCLC-I


chr19: 10625687
ENST00000590382.5
SLC44A2
Intron
SCLC-I


chr19: 10625690
ENST00000590382.5
SLC44A2
Intron
SCLC-I


chr19: 10625691
ENST00000590382.5
SLC44A2
Intron
SCLC-I


chr19: 10625699
ENST00000590382.5
SLC44A2
Intron
SCLC-I


chr19: 10625848
ENST00000590382.5
SLC44A2
Intron
SCLC-I


chr19: 10625854
ENST00000590382.5
SLC44A2
Intron
SCLC-I


chr19: 14440401
ENST00000585619.5
PKN1
Intron
SCLC-I


chr19: 15457540
ENST00000599694.1
RASAL3
Promoter
SCLC-I


chr19: 15457550
ENST00000599694.1
RASAL3
Promoter
SCLC-I


chr19: 15457577
ENST00000599694.1
RASAL3
Promoter
SCLC-I


chr19: 15457579
ENST00000599694.1
RASAL3
Promoter
SCLC-I


chr19: 15457599
ENST00000599694.1
RASAL3
Promoter
SCLC-I


chr19: 17357872
ENST00000595816.1
PLVAP
Intron
SCLC-I


chr19: 17357883
ENST00000595816.1
PLVAP
Intron
SCLC-I


chr19: 18762413
ENST00000338797.10
CRTC1
Intron
SCLC-I


chr19: 32971400
ENST00000305768.10
CEP89
Intron
SCLC-I


chr19: 35033965
ENST00000415950.4
SCN1B
Exon
SCLC-I


chr19: 35249607
ENST00000597933.5
LSR
Intron
SCLC-I


chr19: 35249625
ENST00000597933.5
LSR
Intron
SCLC-I


chr19: 35249634
ENST00000597933.5
LSR
Intron
SCLC-I


chr19: 35249672
ENST00000597933.5
LSR
Intron
SCLC-I


chr19: 38596247
ENST00000589557.1
LOC105372397
Promoter
SCLC-I


chr19: 46494426
ENST00000602017.5
PPP5D1
Intron
SCLC-I


chr19: 46494440
ENST00000602017.5
PPP5D1
Intron
SCLC-I


chr19: 46494443
ENST00000602017.5
PPP5D1
Intron
SCLC-I


chr19: 46494448
ENST00000602017.5
PPP5D1
Intron
SCLC-I


chr19: 46494469
ENST00000602017.5
PPP5D1
Intron
SCLC-I


chr19: 48552206
ENST00000666424.1
NA
Intron
SCLC-I


chr19: 48552207
ENST00000666424.1
NA
Intron
SCLC-I


chr19: 49690337
ENST00000594038.5
CPT1C
Promoter
SCLC-I


chr19: 49690351
ENST00000594038.5
CPT1C
Promoter
SCLC-I


chr19: 49690370
ENST00000594038.5
CPT1C
Promoter
SCLC-I


chr19: 49690375
ENST00000594038.5
CPT1C
Promoter
SCLC-I


chr2: 8545830
ENST00000670008.1
LINC01814
Intron
SCLC-I


chr2: 8545868
ENST00000670008.1
LINC01814
Intron
SCLC-I


chr2: 19356109
ENST00000487581.1
OSR1
Exon
SCLC-I


chr2: 19356152
ENST00000487581.1
OSR1
Exon
SCLC-I


chr2: 19356186
ENST00000487581.1
OSR1
Exon
SCLC-I


chr2: 19356305
ENST00000487581.1
OSR1
Exon
SCLC-I


chr2: 27308111
ENST00000296099.2
UCN
Intron
SCLC-I


chr2: 27308460
ENST00000296099.2
UCN
Promoter
SCLC-I


chr2: 27308503
ENST00000296099.2
UCN
Promoter
SCLC-I


chr2: 27442403
ENST00000407293.5
KRTCAP3
Promoter
SCLC-I


chr2: 27442440
ENST00000407293.5
KRTCAP3
Promoter
SCLC-I


chr2: 27442450
ENST00000464699.5
KRTCAP3
Promoter
SCLC-I


chr2: 27442568
ENST00000464699.5
KRTCAP3
Promoter
SCLC-I


chr2: 27442588
ENST00000464699.5
KRTCAP3
Promoter
SCLC-I


chr2: 60484506
ENST00000646249.1
BCL11A
Intron
SCLC-I


chr2: 63051888
ENST00000366671.7
OTX1
Intron
SCLC-I


chr2: 63052917
ENST00000484066.2
OTX1
Exon
SCLC-I


chr2: 63055800
ENST00000366671.7
OTX1
Exon
SCLC-I


chr2: 65430462
ENST00000356388.9
SPRED2
Intron
SCLC-I


chr2: 66582648
ENST00000433396.5
LINC01798
Intron
SCLC-I


chr2: 68365462
ENST00000234313.8
PLEK
Intron
SCLC-I


chr2: 70904761
ENST00000234392.3
VAX2
Intron
SCLC-I


chr2: 70907108
ENST00000234392.3
VAX2
Intron
SCLC-I


chr2: 73269181
ENST00000521871.5
FBXO41
Exon
SCLC-I


chr2: 97713599
ENST00000264972.9
ZAP70
UTR5
SCLC-I


chr2: 100103855
ENST00000409236.6
AFF3
Intron
SCLC-I


chr2: 100103888
ENST00000409236.6
AFF3
Intron
SCLC-I


chr2: 100103931
ENST00000409236.6
AFF3
Intron
SCLC-I


chr2: 102505500
ENST00000492154.1
SLC9A4
Exon
SCLC-I


chr2: 102505583
ENST00000492154.1
SLC9A4
Exon
SCLC-I


chr2: 109614831
ENST00000415095.5
SEPTIN10
Promoter
SCLC-I


chr2: 109614835
ENST00000415095.5
SEPTIN10
Promoter
SCLC-I


chr2: 109614850
ENST00000437928.5
SEPTIN10
Promoter
SCLC-I


chr2: 109614852
ENST00000437928.5
SEPTIN10
Promoter
SCLC-I


chr2: 113199049
ENST00000409378.1
PSD4
Intron
SCLC-I


chr2: 113199067
ENST00000409378.1
PSD4
Intron
SCLC-I


chr2: 156329800
ENST00000406048.2
NR4A2
Intron
SCLC-I


chr2: 156329803
ENST00000406048.2
NR4A2
Intron
SCLC-I


chr2: 156329809
ENST00000406048.2
NR4A2
Intron
SCLC-I


chr20: 33568553
ENST00000471007.1
CBFA2T2
Intron
SCLC-I


chr20: 33568556
ENST00000471007.1
CBFA2T2
Intron
SCLC-I


chr20: 33568560
ENST00000471007.1
CBFA2T2
Intron
SCLC-I


chr20: 33568562
ENST00000471007.1
CBFA2T2
Intron
SCLC-I


chr20: 37519209
ENST00000467603.1
BLCAP
Intron
SCLC-I


chr20: 37519228
ENST00000467603.1
BLCAP
Intron
SCLC-I


chr20: 37519303
ENST00000397137.5
BLCAP
Exon
SCLC-I


chr20: 37519327
ENST00000397137.5
BLCAP
Exon
SCLC-I


chr20: 49916348
ENST00000289431.10
SPATA2
Promoter
SCLC-I


chr20: 49916358
ENST00000289431.10
SPATA2
Promoter
SCLC-I


chr20: 49916379
ENST00000289431.10
SPATA2
Promoter
SCLC-I


chr20: 50624748
ENST00000327979.8
RIPOR3
Intron
SCLC-I


chr20: 62433875
ENST00000618678.2
NA
Intron
SCLC-I


chr20: 64091986
ENST00000355631.8
OPRL1
Intron
SCLC-I


chr20: 64091995
ENST00000355631.8
OPRL1
Intron
SCLC-I


chr21: 42761195
ENST00000291539.11
PDE9A
Intron
SCLC-I


chr21: 42781489
ENST00000420273.2
NA
Exon
SCLC-I


chr21: 42781516
ENST00000420273.2
NA
Exon
SCLC-I


chr21: 42781722
ENST00000420273.2
NA
Exon
SCLC-I


chr21: 44370400
ENST00000300482.9
TRPM2
Intron
SCLC-I


chr21: 44375502
ENST00000300482.9
TRPM2
Intron
SCLC-I


chr21: 44704883
ENST00000323084.9
TSPEAR
Intron
SCLC-I


chr21: 44706160
ENST00000323084.9
TSPEAR
Intron
SCLC-I


chr21: 44706163
ENST00000323084.9
TSPEAR
Intron
SCLC-I


chr21: 44706566
ENST00000323084.9
TSPEAR
Intron
SCLC-I


chr21: 44706573
ENST00000323084.9
TSPEAR
Intron
SCLC-I


chr21: 44706588
ENST00000323084.9
TSPEAR
Intron
SCLC-I


chr21: 44706603
ENST00000323084.9
TSPEAR
Intron
SCLC-I


chr22: 25779932
ENST00000536101.5
MYO18B
Intron
SCLC-I


chr22: 25779973
ENST00000536101.5
MYO18B
Intron
SCLC-I


chr22: 26645209
ENST00000425548.1
NA
Exon
SCLC-I


chr22: 38291585
ENST00000396832.6
CSNK1E
Exon
SCLC-I


chr22: 38291626
ENST00000396832.6
CSNK1E
Exon
SCLC-I


chr22: 38291631
ENST00000396832.6
CSNK1E
Exon
SCLC-I


chr22: 42314379
ENST00000515426.1
TCF20
Intron
SCLC-I


chr22: 42314380
ENST00000515426.1
TCF20
Intron
SCLC-I


chr22: 43042239
ENST00000266254.12
TTLL1
Intron
SCLC-I


chr22: 43042247
ENST00000266254.12
TTLL1
Intron
SCLC-I


chr22: 49808156
ENST00000438393.5
BRD1
Intron
SCLC-I


chr22: 49808180
ENST00000438393.5
BRD1
Intron
SCLC-I


chr22: 49925568
ENST00000483652.5
CRELD2
Exon
SCLC-I


chr22: 50603738
ENST00000329492.6
MAPK8IP2
Intron
SCLC-I


chr22: 50603740
ENST00000329492.6
MAPK8IP2
Intron
SCLC-I


chr22: 50603745
ENST00000329492.6
MAPK8IP2
Intron
SCLC-I


chr22: 50603747
ENST00000329492.6
MAPK8IP2
Intron
SCLC-I


chr22: 50603755
ENST00000329492.6
MAPK8IP2
Intron
SCLC-I


chr22: 50604086
ENST00000329492.6
MAPK8IP2
Exon
SCLC-I


chr22: 50604120
ENST00000329492.6
MAPK8IP2
Exon
SCLC-I


chr22: 50604139
ENST00000329492.6
MAPK8IP2
Exon
SCLC-I


chr22: 50604146
ENST00000329492.6
MAPK8IP2
Exon
SCLC-I


chr22: 50604201
ENST00000329492.6
MAPK8IP2
Exon
SCLC-I


chr22: 50604208
ENST00000329492.6
MAPK8IP2
Exon
SCLC-I


chr22: 50604219
ENST00000329492.6
MAPK8IP2
Exon
SCLC-I


chr22: 50604229
ENST00000329492.6
MAPK8IP2
Exon
SCLC-I


chr22: 50604231
ENST00000329492.6
MAPK8IP2
Exon
SCLC-I


chr22: 50604233
ENST00000329492.6
MAPK8IP2
Exon
SCLC-I


chr22: 50604241
ENST00000329492.6
MAPK8IP2
Exon
SCLC-I


chr22: 50604242
ENST00000329492.6
MAPK8IP2
Exon
SCLC-I


chr22: 50604243
ENST00000329492.6
MAPK8IP2
Exon
SCLC-I


chr22: 50604246
ENST00000329492.6
MAPK8IP2
Exon
SCLC-I


chr22: 50604251
ENST00000329492.6
MAPK8IP2
Exon
SCLC-I


chr22: 50604272
ENST00000329492.6
MAPK8IP2
Exon
SCLC-I


chr22: 50604293
ENST00000329492.6
MAPK8IP2
Exon
SCLC-I


chr22: 50604297
ENST00000329492.6
MAPK8IP2
Exon
SCLC-I


chr22: 50604298
ENST00000329492.6
MAPK8IP2
Exon
SCLC-I


chr22: 50604304
ENST00000329492.6
MAPK8IP2
Exon
SCLC-I


chr22: 50604310
ENST00000329492.6
MAPK8IP2
Exon
SCLC-I


chr22: 50604316
ENST00000329492.6
MAPK8IP2
Exon
SCLC-I


chr22: 50604514
ENST00000329492.6
MAPK8IP2
Exon
SCLC-I


chr22: 50697638
ENST00000414786.6
SHANK3
Exon
SCLC-I


chr22: 50697649
ENST00000414786.6
SHANK3
Exon
SCLC-I


chr22: 50697652
ENST00000414786.6
SHANK3
Exon
SCLC-I


chr22: 50697660
ENST00000414786.6
SHANK3
Exon
SCLC-I


chr22: 50697669
ENST00000414786.6
SHANK3
Exon
SCLC-I


chr22: 50697682
ENST00000414786.6
SHANK3
Exon
SCLC-I


chr22: 50697690
ENST00000414786.6
SHANK3
Exon
SCLC-I


chr22: 50697698
ENST00000414786.6
SHANK3
Exon
SCLC-I


chr22: 50697700
ENST00000414786.6
SHANK3
Exon
SCLC-I


chr22: 50697703
ENST00000414786.6
SHANK3
Exon
SCLC-I


chr22: 50697709
ENST00000414786.6
SHANK3
Exon
SCLC-I


chr22: 50697725
ENST00000414786.6
SHANK3
Intron
SCLC-I


chr22: 50697727
ENST00000414786.6
SHANK3
Intron
SCLC-I


chr22: 50697745
ENST00000414786.6
SHANK3
Intron
SCLC-I


chr22: 50697751
ENST00000414786.6
SHANK3
Intron
SCLC-I


chr22: 50697828
ENST00000414786.6
SHANK3
Intron
SCLC-I


chr22: 50697861
ENST00000414786.6
SHANK3
Intron
SCLC-I


chr22: 50697894
ENST00000414786.6
SHANK3
Intron
SCLC-I


chr22: 50697898
ENST00000414786.6
SHANK3
Intron
SCLC-I


chr22: 50697908
ENST00000414786.6
SHANK3
Intron
SCLC-I


chr22: 50698101
ENST00000414786.6
SHANK3
Intron
SCLC-I


chr3: 72153149
ENST00000481148.5
LINC00877
Intron
SCLC-I


chr3: 72153167
ENST00000481148.5
LINC00877
Intron
SCLC-I


chr3: 72153179
ENST00000481148.5
LINC00877
Intron
SCLC-I


chr3: 72162393
ENST00000481148.5
LINC00877
Intron
SCLC-I


chr3: 72162409
ENST00000481148.5
LINC00877
Intron
SCLC-I


chr3: 72162418
ENST00000481148.5
LINC00877
Intron
SCLC-I


chr3: 125886263
ENST00000625484.1
LINC02614
Intron
SCLC-I


chr3: 125886271
ENST00000625484.1
LINC02614
Intron
SCLC-I


chr3: 125886293
ENST00000625484.1
LINC02614
Intron
SCLC-I


chr3: 186099366
ENST00000472868.6
ETV5
Intron
SCLC-I


chr3: 196640762
ENST00000328557.5
NRROS
Intron
SCLC-I


chr3: 196640920
ENST00000328557.5
NRROS
Intron
SCLC-I


chr3: 197464061
ENST00000420213.1
NA
Intron
SCLC-I


chr4: 3308936
ENST00000506631.5
RGS12
Intron
SCLC-I


chr4: 3308950
ENST00000506631.5
RGS12
Intron
SCLC-I


chr4: 3308952
ENST00000506631.5
RGS12
Intron
SCLC-I


chr4: 3308956
ENST00000506631.5
RGS12
Intron
SCLC-I


chr4: 3308989
ENST00000506631.5
RGS12
Intron
SCLC-I


chr4: 3310192
ENST00000506631.5
RGS12
Intron
SCLC-I


chr4: 140092663
ENST00000502696.1
MAML3
Intron
SCLC-I


chr4: 140092684
ENST00000502696.1
MAML3
Intron
SCLC-I


chr5: 1207091
ENST00000515652.5
SLC6A19
Intron
SCLC-I


chr5: 1218443
ENST00000515652.5
SLC6A19
Intron
SCLC-I


chr5: 1634751
ENST00000502273.6
LOC728613
Promoter
SCLC-I


chr5: 1634775
ENST00000502273.6
LOC728613
Promoter
SCLC-I


chr5: 1963148
ENST00000660942.1
NA
Intron
SCLC-I


chr5: 3599617
ENST00000559410.1
NA
Intron
SCLC-I


chr5: 3599735
ENST00000559410.1
NA
Intron
SCLC-I


chr5: 3599748
ENST00000559410.1
NA
Intron
SCLC-I


chr5: 93570875
ENST00000656155.1
NR2F1-AS1
Intron
SCLC-I


chr5: 93570877
ENST00000656155.1
NR2F1-AS1
Intron
SCLC-I


chr6: 25179238
ENST00000643807.1
CMAHP
Intron
SCLC-I


chr6: 25179395
ENST00000643807.1
CMAHP
Intron
SCLC-I


chr6: 107634349
ENST00000317357.10
SOBP
Exon
SCLC-I


chr6: 107634371
ENST00000317357.10
SOBP
Exon
SCLC-I


chr6: 107634379
ENST00000317357.10
SOBP
Exon
SCLC-I


chr6: 107634382
ENST00000317357.10
SOBP
Exon
SCLC-I


chr6: 107634391
ENST00000317357.10
SOBP
Exon
SCLC-I


chr6: 107634400
ENST00000317357.10
SOBP
Exon
SCLC-I


chr6: 107634406
ENST00000317357.10
SOBP
Exon
SCLC-I


chr6: 107634416
ENST00000317357.10
SOBP
Exon
SCLC-I


chr6: 107634421
ENST00000317357.10
SOBP
Exon
SCLC-I


chr6: 107634428
ENST00000317357.10
SOBP
Exon
SCLC-I


chr6: 107634434
ENST00000317357.10
SOBP
Exon
SCLC-I


chr6: 107634650
ENST00000317357.10
SOBP
Exon
SCLC-I


chr6: 107634671
ENST00000317357.10
SOBP
Exon
SCLC-I


chr6: 107634681
ENST00000317357.10
SOBP
Exon
SCLC-I


chr6: 107634776
ENST00000317357.10
SOBP
Exon
SCLC-I


chr6: 107634797
ENST00000317357.10
SOBP
Exon
SCLC-I


chr6: 107634800
ENST00000317357.10
SOBP
Exon
SCLC-I


chr6: 107634806
ENST00000317357.10
SOBP
Exon
SCLC-I


chr6: 107634815
ENST00000317357.10
SOBP
Exon
SCLC-I


chr6: 107634825
ENST00000317357.10
SOBP
Exon
SCLC-I


chr6: 107634885
ENST00000317357.10
SOBP
Exon
SCLC-I


chr6: 107634987
ENST00000317357.10
SOBP
Exon
SCLC-I


chr6: 107634992
ENST00000317357.10
SOBP
Exon
SCLC-I


chr6: 107635008
ENST00000317357.10
SOBP
Exon
SCLC-I


chr6: 107635014
ENST00000317357.10
SOBP
Exon
SCLC-I


chr6: 107635027
ENST00000317357.10
SOBP
Exon
SCLC-I


chr6: 107635032
ENST00000317357.10
SOBP
Exon
SCLC-I


chr6: 107635047
ENST00000317357.10
SOBP
Exon
SCLC-I


chr6: 107635056
ENST00000317357.10
SOBP
Exon
SCLC-I


chr6: 108174645
ENST00000368986.8
NR2E1
Intron
SCLC-I


chr6: 108798159
ENST00000655744.1
NA
Promoter
SCLC-I


chr6: 111551876
ENST00000532353.1
TRAF3IP2-AS1
Intron
SCLC-I


chr6: 111551904
ENST00000532353.1
TRAF3IP2-AS1
Intron
SCLC-I


chr6: 111552096
ENST00000532353.1
TRAF3IP2-AS1
Intron
SCLC-I


chr7: 45028581
ENST00000461377.5
CCM2
Intron
SCLC-I


chr7: 45028613
ENST00000461377.5
CCM2
Intron
SCLC-I


chr7: 45768094
ENST00000429741.5
SEPTIN7P2
Intron
SCLC-I


chr7: 45768098
ENST00000429741.5
SEPTIN7P2
Intron
SCLC-I


chr7: 78040283
ENST00000354212.9
MAGI2
Intron
SCLC-I


chr7: 78040332
ENST00000354212.9
MAGI2
Intron
SCLC-I


chr7: 78040354
ENST00000354212.9
MAGI2
Intron
SCLC-I


chr7: 78040430
ENST00000354212.9
MAGI2
Intron
SCLC-I


chr7: 78040432
ENST00000354212.9
MAGI2
Intron
SCLC-I


chr7: 101232397
ENST00000308344.9
CLDN15
Exon
SCLC-I


chr7: 101232416
ENST00000308344.9
CLDN15
Exon
SCLC-I


chr7: 101232422
ENST00000308344.9
CLDN15
Exon
SCLC-I


chr7: 101232431
ENST00000308344.9
CLDN15
Exon
SCLC-I


chr7: 101232465
ENST00000308344.9
CLDN15
Exon
SCLC-I


chr7: 101232485
ENST00000308344.9
CLDN15
Exon
SCLC-I


chr7: 101232508
ENST00000308344.9
CLDN15
Exon
SCLC-I


chr7: 101232511
ENST00000308344.9
CLDN15
Exon
SCLC-I


chr7: 150958216
ENST00000262186.10
KCNH2
Exon
SCLC-I


chr7: 150958354
ENST00000262186.10
KCNH2
Exon
SCLC-I


chr7: 150958396
ENST00000262186.10
KCNH2
Exon
SCLC-I


chr7: 150958403
ENST00000262186.10
KCNH2
Exon
SCLC-I


chr8: 8892326
ENST00000276282.7
MFHAS1
Exon
SCLC-I


chr8: 8892330
ENST00000276282.7
MFHAS1
Exon
SCLC-I


chr8: 8892336
ENST00000276282.7
MFHAS1
Exon
SCLC-I


chr8: 8892337
ENST00000276282.7
MFHAS1
Exon
SCLC-I


chr8: 8892347
ENST00000276282.7
MFHAS1
Exon
SCLC-I


chr8: 8892409
ENST00000276282.7
MFHAS1
Exon
SCLC-I


chr8: 8892410
ENST00000276282.7
MFHAS1
Exon
SCLC-I


chr8: 8892416
ENST00000276282.7
MFHAS1
Exon
SCLC-I


chr8: 11474156
ENST00000527445.1
FAM167A
Intron
SCLC-I


chr8: 11474157
ENST00000527445.1
FAM167A
Intron
SCLC-I


chr8: 11474164
ENST00000527445.1
FAM167A
Intron
SCLC-I


chr8: 11474171
ENST00000527445.1
FAM167A
Intron
SCLC-I


chr8: 22643830
ENST00000519513.5
BIN3
Intron
SCLC-I


chr8: 22643945
ENST00000519513.5
BIN3
Intron
SCLC-I


chr8: 60946896
ENST00000526936.5
NA
Intron
SCLC-I


chr8: 60946919
ENST00000526936.5
NA
Intron
SCLC-I


chr8: 144467777
ENST00000529644.1
KIFC2
Exon
SCLC-I


chr9: 34457430
ENST00000379080.5
FAM219A
Intron
SCLC-I


chr9: 34457464
ENST00000379080.5
FAM219A
Intron
SCLC-I


chr9: 113400746
ENST00000464749.5
ALAD
Intron
SCLC-I


chr9: 113463513
ENST00000374140.6
RGS3
Intron
SCLC-I


chr9: 113463523
ENST00000374140.6
RGS3
Intron
SCLC-I


chr9: 113463527
ENST00000374140.6
RGS3
Intron
SCLC-I


chr9: 113463528
ENST00000374140.6
RGS3
Intron
SCLC-I


chr9: 113463555
ENST00000374140.6
RGS3
Intron
SCLC-I


chr9: 113463557
ENST00000374140.6
RGS3
Intron
SCLC-I


chr9: 113463558
ENST00000374140.6
RGS3
Intron
SCLC-I


chr9: 113463567
ENST00000374140.6
RGS3
Intron
SCLC-I


chr9: 113463568
ENST00000374140.6
RGS3
Intron
SCLC-I


chr9: 113463569
ENST00000374140.6
RGS3
Intron
SCLC-I


chr9: 113463570
ENST00000374140.6
RGS3
Intron
SCLC-I


chr9: 113463574
ENST00000374140.6
RGS3
Intron
SCLC-I


chr9: 113463575
ENST00000374140.6
RGS3
Intron
SCLC-I


chr9: 113463578
ENST00000374140.6
RGS3
Intron
SCLC-I


chr9: 113463581
ENST00000374140.6
RGS3
Intron
SCLC-I


chr9: 113463598
ENST00000374140.6
RGS3
Intron
SCLC-I


chr9: 127754240
ENST00000468969.6
SH2D3C
Intron
SCLC-I


chr9: 127754243
ENST00000468969.6
SH2D3C
Intron
SCLC-I


chr9: 127754244
ENST00000468969.6
SH2D3C
Intron
SCLC-I


chr9: 127754260
ENST00000468969.6
SH2D3C
Intron
SCLC-I


chr9: 127754261
ENST00000468969.6
SH2D3C
Intron
SCLC-I


chr9: 127754267
ENST00000468969.6
SH2D3C
Intron
SCLC-I


chr9: 127754268
ENST00000468969.6
SH2D3C
Intron
SCLC-I


chr9: 127754269
ENST00000468969.6
SH2D3C
Intron
SCLC-I


chr9: 127754270
ENST00000468969.6
SH2D3C
Intron
SCLC-I


chr9: 127754273
ENST00000468969.6
SH2D3C
Intron
SCLC-I


chr9: 127754274
ENST00000468969.6
SH2D3C
Intron
SCLC-I


chr9: 127754294
ENST00000468969.6
SH2D3C
Intron
SCLC-I


chr9: 127754301
ENST00000468969.6
SH2D3C
Intron
SCLC-I


chr9: 127754302
ENST00000468969.6
SH2D3C
Intron
SCLC-I


chr9: 127754304
ENST00000468969.6
SH2D3C
Intron
SCLC-I


chr9: 127754305
ENST00000468969.6
SH2D3C
Intron
SCLC-I


chr9: 127754307
ENST00000468969.6
SH2D3C
Intron
SCLC-I


chr9: 127754342
ENST00000468969.6
SH2D3C
Intron
SCLC-I


chr9: 127754343
ENST00000468969.6
SH2D3C
Intron
SCLC-I


chr9: 127754345
ENST00000468969.6
SH2D3C
Intron
SCLC-I


chr9: 127754355
ENST00000468969.6
SH2D3C
Intron
SCLC-I


chr9: 127754649
ENST00000468969.6
SH2D3C
Intron
SCLC-I


chr9: 127754836
ENST00000468969.6
SH2D3C
Intron
SCLC-I


chr9: 127754846
ENST00000468969.6
SH2D3C
Intron
SCLC-I


chr9: 127754871
ENST00000468969.6
SH2D3C
Intron
SCLC-I


chr9: 127754889
ENST00000468969.6
SH2D3C
Intron
SCLC-I


chr9: 127754894
ENST00000468969.6
SH2D3C
Intron
SCLC-I


chr9: 127755283
ENST00000468969.6
SH2D3C
Intron
SCLC-I


chr9: 127755336
ENST00000468969.6
SH2D3C
Intron
SCLC-I


chr9: 127755497
ENST00000468969.6
SH2D3C
Intron
SCLC-I


chr9: 127755519
ENST00000468969.6
SH2D3C
Intron
SCLC-I


chr9: 127755545
ENST00000468969.6
SH2D3C
Intron
SCLC-I


chr9: 127755548
ENST00000468969.6
SH2D3C
Intron
SCLC-I


chr9: 127755564
ENST00000468969.6
SH2D3C
Intron
SCLC-I


chr9: 129495716
ENST00000653047.1
LINC00963
Intron
SCLC-I


chr9: 129495789
ENST00000653047.1
LINC00963
Intron
SCLC-I


chr9: 131554650
ENST00000636672.1
PRRT1B
Exon
SCLC-I


chr9: 131554658
ENST00000636672.1
PRRT1B
Exon
SCLC-I


chr9: 131554659
ENST00000636672.1
PRRT1B
Exon
SCLC-I


chr9: 131554660
ENST00000636672.1
PRRT1B
Exon
SCLC-I


chr9: 131554665
ENST00000636672.1
PRRT1B
Exon
SCLC-I


chr9: 131554666
ENST00000636672.1
PRRT1B
Exon
SCLC-I


chr9: 131554674
ENST00000636672.1
PRRT1B
Exon
SCLC-I


chr9: 131554676
ENST00000636672.1
PRRT1B
Exon
SCLC-I


chr9: 131554679
ENST00000636672.1
PRRT1B
Exon
SCLC-I


chr9: 131554683
ENST00000636672.1
PRRT1B
Exon
SCLC-I


chr9: 131554685
ENST00000636672.1
PRRT1B
Exon
SCLC-I


chr9: 131554696
ENST00000636672.1
PRRT1B
Exon
SCLC-I


chr9: 131554702
ENST00000636672.1
PRRT1B
Exon
SCLC-I


chr9: 131554707
ENST00000636672.1
PRRT1B
Exon
SCLC-I


chr9: 131554714
ENST00000636672.1
PRRT1B
Exon
SCLC-I


chr9: 131554750
ENST00000636672.1
PRRT1B
Exon
SCLC-I


chr9: 131885496
ENST00000357028.6
MED27
Intron
SCLC-I


chr9: 132037677
ENST00000651950.1
MED27
Intron
SCLC-I


chr9: 136076236
ENST00000277554.4
NACC2
Intron
SCLC-I


chr9: 136076244
ENST00000277554.4
NACC2
Intron
SCLC-I


chr9: 136076251
ENST00000277554.4
NACC2
Intron
SCLC-I









Example 6—Methylation Markers for Analysis of Tumor Burden

Whole genome sequencing and methylation analysis data was obtained from cell free DNA (cfDNA) from SCLC patients. 42 methylation sites were identified that correlated well with general tumor burden in the patients. These methylation sites are provided in Table 21.









TABLE 24





Methylation sites having methylation levels


correlated with general tumor burden in SCLC


Methylation Site

















chr5: 77844815



chr5: 77844832



chr5: 77844821



chr5: 132257679



chr16: 49280789



chr21: 34670607



chr21: 34670604



chr21: 34670609



chr6: 108176627



chr10: 71638792



chr5: 132257648



chr5: 132257653



chr5: 132257685



chr5: 132257670



chr5: 138274351



chr8: 22139065



chr5: 132257664



chr5: 132257652



chr5: 132257666



chr3: 38039198



chr9: 137591221



chr9: 131444459



chr6: 108176609



chr5: 132257661



chr5: 132257650



chr5: 132257703



chr5: 132257682



chr5: 178860732



chr5: 132257676



chr20: 22582930



chr2: 10043081



chr2: 98347974



chr5: 132257649



chr5: 178860742



chr5: 138274357



chr5: 138274360



chr10: 75408778



chr5: 132257647



chr5: 132257637



chr6: 108176612



chr22: 50251762



chr21: 34669575










Example 7—Tumor- and Circulating-Free DNA Methylation Identifies Clinically Relevant Small Cell Lung Cancer Subtypes

Here, the inventors assessed DNA methylation and gene expression from a cohort of predominantly extensive stage SCLC with tissue and/or plasma samples and developed machine learning approaches to allow the classification of SCLC subtypes from clinical specimen in both tissue and liquid biopsies in order to identify SCLC subgroups and enable precision medicine in SCLC.


Cohort of Clinical Specimens for RNAseq and DNA Methylation Profiling


Given the finding that DNA methylation was able to detect SCLC from plasma, the inventors next hypothesized that DNA methylation can be exploited as a biomarker in SCLC. To this end the inventors investigated a cohort of 105 samples with predominantly extensive-stage SCLC (Table 1). For 85 samples the inventors obtained RNAseq data and for 83 samples the inventors obtained DNA methylation data using reduced representation bisulfite sequencing (RRBS), with 66 samples having both, RNAseq and RRBS data. The three groups were balanced among sex, stage and subtypes (Table 25). Further data on the cohort is summarized in FIG. 23. To further confirm the subgroup identity and the reliability of the RNAseq data, results were compared to qPCR of the three transcription factors (ASCL1. NEUROD1 and POU2F3) to ensure reliability. The inventors observed a high correlation with R=−0.94, R=−0.88, R=−0.55, respectively (FIGS. 24A-24C).














TABLE 25










Chi-



All
RNAseq
RRBS
sq p




















N
105
85
83
















Age

66
(26-96)
66
(28-96)
66
(26-89)



(range)


Sex (%)
F
57
(54%)
45
(53%)
46
(55%)
0.949



M
48
(46%)
40
(47%)
37
(45%)


Stage (%)
LS
28
(27%)
25
(29%)
22
(27%)
0.890



ES
77
(73%)
60
(71%)
61
(73%)


Subtype
SCLC-A
66
(63%)
49
(58%)
57
(60%)
0.863


(%)
SCLC-N
22
(21%)
22
(26%)
19
(24%)



SCLC-P
4
(4%)
4
(5%)
3
(4%)



SCLC-I
8
(8%)
8
(9%)
4
(5%)



equivocal
2
(2%)
2
(2%)
0
(6%)



unknown
3
(3%)
0
(0%)
0
(0%)









Clinical SCLC can be Classified Using a Reduced Machine Learning RNAseq Signature


The inventors previously reported that SCLC can be classified in four distinct subtypes using a gene expression classifier derived from non-negative matrix factorization11 from using mRNA expression data from a cohort 20 of limited stage SCLC surgical specimens and the IMPower133 dataset from a randomized phase 3 clinical trial assessing the combination of first-line platinum-etoposide chemotherapy with or without atezolizumab2, comprised of extensive stage SCLC specimens. Building on this analysis, the inventors developed a classifier in order to reduce the number of genes required to subtype tumors and facilitate the subtype classification using different mRNA profiling methods. Using a consensus classification (see online methods) incorporating 181 genes, the inventors were able to unambiguously classify the majority of samples into a single subtype, and expression of the previously established transcription factors (ASCL1 for SCLC-A. NEUROD1 for SCLC-N and POU2F3 for SCLC-P) was well correlated with the classification (FIG. 19A). For 81/85 samples, a clear classification was obtained, with 47/81 (58%), 22/81 (27%), 4/810 (5%), 8/81 (10%) representing the SCLC-A, SCLC-N, SCLC-P and SCLC-I subtypes, respectively. This distribution is close to the observed distribution in the IMpower133 study with SCLC-A—51%, SCLC-N—23%. SCLC-I—18%. SCLC-P—7%11 (chi-sq p=0.2116). As previously published, the SCLC-A and SCLC-N samples in the cohort demonstrated a higher expression of neuroendocrine genes compared to SCLC-P and SCLC-I (FIG. 19B) while the latter was also characterized by a more mesenchymal polarization (FIG. 19C; ANOVA p=0.032). Likewise, expression of HLA and other immune-related genes was higher in SCLC-P and SCLC-I subtype (FIGS. 25A and 25B), providing evidence that the classification is valid and the phenotypes consistent between the datasets. Only few specimens failed classification (4/81: 4.9%) due to what appeared to be technical limitations and RNA quality (FIG. 19B). Consequently, with a success rate of 95%, the classification approach is highly robust, comprises of only a limited number of 181 genes whose assessment is technically less challenging than larger gene panels, and clearly allows routine classification.


DNA Methylation Varies Across SCLC Subtypes


The inventors then analyzed the differences of DNA methylation in the dataset. The methylation level was averaged across bins of 100 kb width and calculated the mean for those bins per subtype (FIG. 20A). To determine the genome-wide methylation level, the rolling average was calculated over 500 bins (=50 Mbp). The analysis highlighted profound differences in the global methylation level per subtype, with the SCLC-P subtype presenting with a hypomethylated phenotype and SCLC-N with a hypermethylated phenotype, while SCLC-A and SCLC-I were comparable (FIG. 20A). The inventors further analyzed 59 SCLC-derived cell lines across all four subtypes as well as 12 patient-derived xenograft models that span all but the SCLC-I phenotype, together with two previously published datasets on cell lines. Interestingly, in cell lines, SCLC-P was hypermethylated (FIG. 26A) which was confirmed in two independent datasets of cell lines from the NCI SCLC cell miner project21 (FIG. 26B) and the GDSC22 (FIG. 26C), while the xenograft models confirmed the hypomethylated phenotype in SCLC-P (FIG. 26D). The inventors analyzed the association of single DNA methylation sites in FFPE samples and cell lines using receiver operator characteristics and filtered for methylation sites that were present in both FFPE samples and cell lines. When comparing DNA methylation sites that were highly associated with one of the subtypes (AUROC >0.8), only few were shared among the two datasets even though some DNA methylation sites were highly associated with the respective subtype in both datasets (FIG. 27A-27D), highlighting that cell lines and FFPE samples share some similarities despite the genome-wide differences. The inventors further annotated the methylation sites by their association with genes and compared the differences. The inventors selected the hypermethylated regions (FIG. 20B), defined by >90% methylation level, and the hypomethylated regions (FIG. 20C), defined by <10% methylation level. Interestingly, most of those regions were conserved across the subtypes and only a few regions were specific to each. The inventors further analyzed the association of each region with one of the subtypes using receiver operator characteristics and analyzed regions with +/−20% differences of the subtype versus the other subtypes for SCLC-A (FIG. 20D), SCLC-N(FIG. 20E), SCLC-P (FIG. 20F) and SCLC-I (FIG. 20G). Importantly, while only few regions were specific to SCLC-A and SCLC-N, the inventors saw many regions that were specific to the SCLC-P and SCLC-I subtypes, respectively, which revealed that those subtypes harbor more specific methylated regions. As the four subtypes are defined by the expression of the three transcription factors, ASCL1, NEUROD1 and POU2F3, the inventors analyzed the methylation in those genes between the subtypes (FIG. 28A-28C). The inventors have previously demonstrated in a comparison of cell lines of the SCLC-A and SCLC-N subtype, that NEUROD1 promoter methylation is reduced in SCLC-N and confirmed this finding in tumor specimen (FIG. 28B). Other than this case, however, methylation in regions associated with those genes did not differ strongly across the subtypes. Consequently, the regulation of these specific transcription factors by DNA methylation might be limited and consequently analysis of only those regions does not appear to be adequate to differentiate between SCLC subtypes. Nevertheless, the inventors saw marked differences in the average methylation level across specific regions (FIG. 29). Consequently, profound differences in the DNA methylation composition between the four subtypes confirmed the pivotal role of epigenetic regulation in SCLC.


DNA Methylation can be Used to Classify SCLC Specimen


These findings suggested that differences in DNA methylation could be exploited for the generation of biomarkers that are able to differentiate SCLC subtypes. In order to first generate models that work across different datasets and to capture the variability across SCLC, the inventors combined data from the clinical tumor specimens and cell lines to define DNA methylation sites that are associated with each of the four subtypes in both datasets using ROC. The inventors then selected the top 500 sites for each of the four subtypes and created models that were trained only on the clinical tumor specimens by randomly selecting 5, 10, or 20 methylation sites per subtype. The inventors selected for models that had an accuracy=100% and used a consensus of 50% across the models to call a subtype, similar to the RNAseq approach (FIG. 21A). Accuracy for samples that have been associated with one of the four subtypes using RNAseq and DNA methylation was 98.3% (95% CI: 91.1%-99.9%; Kappa=0.9706) with the DNA methylation-based classifier (SCLC-DMC). Importantly, the SCLC-DMC approach allowed the subtyping of 17 additional samples for which no RNAseq data was available and thus RNA-based classification was impossible. Furthermore, for 2 samples with equivocal classification in RNAseq, the SCLC-DMC allowed the association of a subtype (FIG. 21A).


Prior studies indicated that the SCLC subtypes differ in terms of their tumor microenvironment; for example, the SCLC-I subgroup was more inflamed with enrichment for immune-related checkpoint factors and likewise in SCLC-P, tumor microenvironment is enriched. It was therefore expected that cell lines could not fully recapitulate differences between the subgroups observed using clinical specimens. To test this, the inventors investigated how the SCLC-DMC on the classification of cell lines. While the accuracy was high (accuracy=90.9%; 95% CI: 80.0%-97.0%), the SCLC-DMC failed to classify SCLC-P and SCLC-I (FIG. 30). While this highlights that DNA methylation sites are conserved to a significant extent between cell lines and tumor samples, it further demonstrates the limitations in relying on exclusively on cell line data which is lacking the tumor microenvironment that is especially important in those two subtypes where classification failed, and thus limits its classification. Crucially, despite limited capabilities in cell lines, the SCLC-DMC was highly reliable and precise in defining subtypes in clinical SCLC samples.


DNA Methylation is Preserved in cfDNA


As DNA methylation was highly associated with SCLC subtypes in the dataset, the inventors further hypothesized that DNA methylation from plasma might equally serve for the classification of SCLC. The inventors consequently analyzed DNA methylation in 8 matched plasma samples (of which the inventors had matched FFPE RRBS for 5), which covered all but the SCLC-P subtype. Importantly, the DNA methylation profile across the genome was comparable to the FFPE samples (FIG. 21B). Furthermore, the inventors analyzed the differences for each sample between the cfDNA and FFPE DNA methylation data (FIG. 31A) and observed that differences between the DNA sources were minor and that DNA methylation was preserved between FFPE and cfDNA. Additionally, the inventors retrieved previously published cfRRBS data from healthy donors23 to use as control samples. The profile of all samples was comparable to the healthy donor cfDNA profile (FIG. 31B), with the exception of JHSC-0050 where the profile differed markedly. The classification of SCLC subtypes from the cfDNA was performed using the SCLC-DMC that was trained on clinical FFPE specimens and was not further adjusted for the cfDNA input. Nevertheless, classification was possible for most samples (83.3%, 95% CI: 35.88%-99.6%; Kappa=0.7143) with all but one subtype being correctly classified (FIG. 21C). However, two samples failed classification including JHSC-0050 which had an abnormal cfDNA pattern and thus it is feasible that cfDNA in this sample was of poor quality.


DNA Methylation Predicts Drug Response and Clinical Outcome Similar to Gene Expression


Previously, it was demonstrated that, in vitro, cell lines assigned to SCLC-A and SCLC-N by gene expression possessed unique therapeutic vulnerabilities11. To validate that these same vulnerabilities are preserved using the methylation classifier (FIG. 30), the inventors compared IC50 values for over 400 drugs24 between methylation-assigned SCLC-A and SCLC-N subtypes and identified numerous distinct vulnerabilities between the groups. For example, as demonstrated with the gene expression classifier, SCLC-A cell lines were more sensitive to BCL2 inhibitors (BCL2i) (e.g. ABT-737) (FIG. 22A), while SCLC-N cell lines were more sensitive to Aurora kinase inhibitors (AURKi) (e.g. CYC-116) (FIG. 22B).


Finally, to determine whether methylation- and RNA-based subtyping approaches yielded comparable clinical outcomes among SCLC patients, the inventors used RNAseq gene expression or SCLC-DMC for patients with extensive stage SCLC with known clinical outcomes. While many samples had both RNA and methylation data present, several of the patients were only subtyped by one of the two methods. To ensure adequate statistical power for the analysis, the inventors focused on the two most prevalent subtypes, SCLC-A and SCLC-N, respectively and filtered for ES-SCLC only. Importantly, when comparing the two approaches, overall survival was comparable for patients identified as SCLC-A (HR (95% CI)=1.11 (0.6-2.05); FIG. 22C). Similar results were observed for patients identified as the SCLC-N subtype using the two approaches (HR=1.04 (0.46-2.31); FIG. 22D) when using RNAseq or SCLC-DMC, providing evidence that DNA methylation is able to predict drug response in vitro similar to RNA-based classification and that DNA methylation can indeed be used for clinically reliable subtyping of SCLC.


Methods


Patient Selection


All patients were consented to the GEMINI protocol at the UT MD Anderson Cancer Center (UT MDACC). Totally 105 samples have been selected after pathological examination of the tissue quality. Each sample was required to have >100 tumor cell in each specimen, and at least 2 slides of tissue sections was required for inclusion in the study.


Clinical Data


Clinical data was retrieved from the GEMINI database which included clinical data obtained during treatment at the UT MDACC and consent was provided for accessing the clinical data. Additional data was retrieved manually and reviewed by three board-certified oncologists. For the analysis of survival, overall survival was calculated by time from date of diagnosis to death and patients with lost follow-up were censored at the date where the last information was obtained. Survival analysis was performed using Kaplan-Meier analysis and cox-proportional hazard ratio estimation using the survminer package in R.


Nucleic Acid Extraction


For the nucleic acid extraction, two slides of FFPE tissue samples were cut at 5 μm each. For each sample, tumor area was highlighted by a board-certified Pathologist and macrodissection was used prior to extraction, if necessary. For combined RNA and DNA extraction, the MagMAX FFPE DNA/RNA Ultra Kit (Thermo Fisher Scientific, A31881) was used following the manufacturer's protocol. DNA concentration was assessed using the Qubit 1× dsDNA HS Assay Kit and a Qubit 2.0 fluorimeter. For RNA, concentration was measured using the Qubit RNA high sensitivity (HS) assay kit. RNA quality was analyzed using the Agilent RNA 6000 Pico kit on a 2100 Bioanalyzer.


Following extraction, the expression of the three transcription factors, ASCL1 (BioRad Prime PCR Human Cy5 [qHsaCEP0025578]), NEUROD1 (BioRad PrimePCR Human HEX [qHsaCEP0053288]) and POU2F3 (BioRad PrimePCR Human FAM [qHsaCEP0052042]) was assessed using the Reliance One-Step Multiplex RT-qPCR Supermix (Biorad). Briefly, 2 μl of extracted RNA was directly used for the 1-Step qPCR that includes reverse transcription and amplification in one step on a CFX96 qPCR device (BioRad). GAPDH (BioRad PrimePCR Human Cy5.5 [qHsaCEP0052324]) was used a housekeeper and delta-cT values were calculated for each sample.


For cfDNA extraction, 2-3 ml Plasma obtained in Streck Cell-Free DNA BCT tubes was used for each sample. cfDNA was extracted using the Apostle MiniMax High Efficiency Cell-Free DNA Isolation Kit (Apostle Inc). cfDNA concentration was assessed using the Qubit 1× dsDNA HS Assay Kit and a Qubit 2.0 fluorimeter.


RNAseq


For RNAseq, samples were selected based on the DV200 value and for their expression in qPCR. Upon expert revision, 85 samples have been selected for RNA sequencing. All samples were treated with DNase treatment using DNase I (ThermoFisher, Massachusetts, USA) prior to RNAseq to reduce DNA contamination that might interfere with downstream results. Library generation using the SMARTer Stranded Total RNAseq Kit V3 (Takara Bio USA Inc., California, USA) was performed following the manufacturer's instructions. Final library quantity was measured by KAPA SYBR FAST qPCR and library quality was evaluated using a TapeStation D1000 ScreenTape (Agilent Technologies, CA, USA). Libraries were sequenced on an Illumina NovaSeq instrument (Illumina, California. USA) with a read length configuration of 150 PE for 80M PE reads per sample (40M clusters). Fastq files were quality trimmed using trimmomatic and aligned to the GRCh38 transcriptome using salmon v1.6.0.


Due to the highly degraded RNA and the limited sample input, all RNAseq results were correlated to the qPCR (FIG. 23). Importantly, expression data was highly correlated for ASCL1 (Pearson r=0.94: p<0.0001) and NEUROD1 (Pearson r=0.88: p<0.0001) with good correlation for POU2F3 (Pearson r=0.55: p<0.0001) highlighting the reliability of the RNAseq data despite these limitations. However, NEUROD1 detection using RNAseq was reduced compared to qPCR, highlighting a certain limitation of the RNAseq data in detecting low-expression genes.


RRBS


To analyze DNA Methylation across the genome, RRBS (Reduced Representation Bisulfite Sequencing) was utilized using the Ovation RRBS Methyl-Seq kit (Tecan Group Ltd., Zurich. Switzerland). To account for the highly degraded DNA from FFPE and plasma samples, the material was first treated with one unit of Shrimp Alkaline Phosphatase (New England Biolabs, Ipswich, MA) to remove phosphorylated DNA which might interfere with downstream analysis23. Briefly, 0.1-100 ng of genomic DNA was digested using MspI, and Illumina-compatible cytosine-methylated adaptor were ligated to the enzyme-digested DNA. For lower concentrations of DNA, adapters were diluted 1:40 to 1:120, in order to decrease the representation of randomly fragmented DNA and adapter-dimers in the final library. RRBS libraries were then visualized using Bioanalyzer High Sensitivity DNA chips (Agilent, Santa Clara. CA), and those passing QC were subsequently sequenced as 100 bp paired-end reads on an Illumina NovaSeq instrument with a target sequencing depth of 300M PE reads (150M clusters). After sequencing, Fastq files were obtained and adapters were trimmed using trimmomatic. Alignment and retrieval of DNA Methylation (in percent of total methylated Cytosines) was performed using Bismark v 0.22 n against the GRCh38 human genome. Samples with <50% mapping rate and, <60M aligned reads were excluded from further analysis. Finally, cytosines with coverage <10 were filtered out to assure high confidence DNA Methylation analysis.


For cell lines and CDX models, 100 ng of RNA was used using the Ovation RRBS Methyl-Seq kit (Tecan Group Ltd., Zurich, Switzerland) as for the clinical samples but without the initial phosphatase step. Sequencing was performed in a single Read 57 bp configuration on a Illumina HiSeq 3000 sequencer. Data processing was performed likewise using Bismark v 0.22. Annotations of methylated regions was performed using the annotatr package and the Hg38 database.


Generation of Predictive Models for Classification Using RNAseq


It was hypothesized that using gene ratios of one gene over another gene might be more robust to classify SCLC across different datasets than using the single expression value. For this purpose, the inventors combined the data retrieved from George et al. comprising of surgical SCLC specimen and the data from the IMPower133 clinical trial as published in Gay C M et al. While for the latter only limited genes were published, the inventors filtered for genes that were present in both datasets that served as training set. ROC analysis was used to define the genes which were mostly associated with one of the four subtypes and selected the top 50 genes for each subtype for further validation which resulted in 181 genes used after removing duplicated genes (Table 26). The inventors then created all different gene ratios of those genes. To select highly relevant gene ratios, the inventors created predictive models, incorporating randomly selected 20 gene ratios per model with 500 distinct models for each of the four subtypes (totally 2000 models created). For the training, the caret package in R was used, and extreme gradient boosting with DART (Dropout Additive Regression Trees) was utilized with repeated cross validation with a 5-fold split and 20 repeats during training. Following, only models with an accuracy=1 on the training data were retained. Those models were then used to define the subtypes in the clinical dataset. In order to obtain the most generalized subtype classification, the inventors used all models for the prediction and if >50% of the models agreed on the subtype, the subtype was called based on this consensus classification. Samples with less than 50% agreement are called “equivocal” as a clear classification could not be obtained with the current methodology.














TABLE 26









SH2D2A
WNT11
POU2F3
LCP2



SCN2A
NHLH1
RIMKLA
CTSS



SCN3A
SSTR2
KCNF1
CD53



SCG2
ID2
ELAVL4
PTPN22



DDC
ARHGEF38
TCERG1L
GIMAP2



ICA1
SHF
CPLX2
CD74



CNKSR3
SEMA6A
CHGA
FGL2



ASCL1
NEUROD1
KCNH6
CXCR6



FOXA2
TEC
FAM105A
TIGIT



PTPRN2
FNDC5
ANO7
ITK



FZD7
RAB11FIP1
FBLN7
SLFN12L



PREX1
SLC17A6
KCNK3
SASH3



SYT1
SH2D3A
ST8SIA5
RASAL3



ZNF217
POF1B
GRIK3
HLA-DMA



LDLRAP1
PRIMA1
C1QL1
HLA-DMB



MGAT4C
TFF3
CHD7
ARHGAP30



CXXC4
EFNB1
KCNMB2
CASP1



RILPL2
ALDH1A1
RTBDN
SELPLG



RGL1
CASP4
HCN2
IL10RA



PPARD
HUNK
RGS7
PTAFR



ETS2
SMO
MAP2
CCR5



GJB1
RBFOX3
SOX9
P2RY10



HABP2
ELF1
TRIM9
CASP10



RNF148
ALK
FAM131A
EVI2A



STX19
HSH2D
MYC
ITGAL



SEC11C
PRKX
NRXN1
TNFAIP8L2



CADPS2
BCL3
RFX2
DOK2



EMP3
GLI2
UNC80
PTPN7



FAM124A
CHRNA3
INSM1
CSF2RB



SYT4
CEACAM5
GRP
ICOS



RARG
MDGA1
VWA5B2
WIPF1



LRMP
ATOH7
ISL1
CCR2



NCALD
MMP24
ANXA4
CYBB



PRUNE2
VAV1
IL2RB
SLAMF1



REST
KLF4
GIMAP7



FAM78A
PCDH8
KLHL6



RNF133
SEZ6L
PTPRC



RGS17
CPE
NLRC3



MAT2B
PCSK2
CCDC69



NELL1
CA8
MPEG1



BLNK
C11orf53
SNX20



BTN2A2
PCSK1
HLA-DRA



GCH1
CAMK2N2
JAK3



EFNA4
JAKMIP2
ARHGAP15



LCN15
GNAO1
TNFRSF1B



SMPD3
DGKB
GIMAP4



CPVL
GFI1B
CD2



EXTL3
ASCL2
IL2RG



ADCY7
CACNA1A
CD96










Generation of Predictive Models for Classification Using DNA Methylation Data


To generate models with broader applicability, the inventors combined data from the cell lines and the clinical GEMINI cohort in order to tune models to work across different sample types. The selected DNA Methylation sites were filtered to be present in both datasets. Following, the inventors performed ROC analysis on the combined set to select the methylation sites that had the highest association with one of the four subtypes. The inventors selected the top 500 methylation sites (by AUROC, Tables 27-30) for each of the four subtypes and created models by randomly selecting 5, 10, or 20 methylation per subtype per model. For each number of methylation sites, 500 models were created using xgboost with DART and 3-fold cross validation with 20 repeats using the training set. Due to the presence of missing values in the dataset, the inventors used median imputation to replace missing values. Models were used to predict the subtype of the samples in the training and testing set. Only models with an accuracy=1 were maintained and used to predict the subtype on the full GEMINI dataset. Similar to the RNAseq approach, a subtype was called when >50% agreed on the subtype. If <50% agreement was achieved, the subtype was classified as “equivocal” due to the lack of consensus. The same models and classification strategy were pursued for the cfDNA samples as well as for cell lines.









TABLE 27







DNA methylation sites associated with SCLC-A











MethylationSite
AUC
threshold
specificity
sensitivity














chr17: 74961036
1
82.9326923
1
1


chr17: 74961013
0.978788
53.5294118
0.90909091
1


chr18: 59062159
0.965686
92.9802956
1
0.85294118


chr19: 13506705
0.964286
75.5007257
1
0.91428571


chr9: 134815629
0.963265
77.7985075
0.85714286
0.97142857


chr21: 41180000
0.961616
91.1538462
0.86666667
0.93939394


chr9: 93014411
0.959034
64.9122807
0.92857143
0.94117647


chr9: 114211349
0.958824
76.1111111
1
0.85294118


chr9: 134810271
0.955236
82.9710145
0.875
0.94594595


chr19: 3385734
0.952941
80.7407407
1
0.82352941


chr6: 51213948
0.952679
10.5555556
0.875
0.91428571


chr18: 27786347
0.94958
7.76723277
1
0.79411765


chr6: 168638645
0.94958
94.4837162
1
0.79411765


chr9: 134815657
0.94898
85.6516291
0.92857143
0.91428571


chr9: 134815611
0.948962
48.3333333
0.94117647
0.85294118


chr16: 84519934
0.948529
38.9569161
0.9375
0.85294118


chr20: 20364625
0.948148
1.54838456
0.93333333
0.88888889


chr5: 172103442
0.947619
81.1764706
1
0.8


chr20: 22598951
0.947059
90.8333333
0.8
0.94117647


chr16: 85355101
0.946691
86.0226105
0.9375
0.88235294


chr9: 134815628
0.946367
52.2435897
1
0.85294118


chr20: 20364629
0.944762
7.53052917
0.93333333
0.91428571


chr19: 511206
0.944444
27.1929825
0.83333333
1


chr6: 168149181
0.944328
72.4164134
0.85714286
0.94117647


chr7: 100122306
0.943137
18.3333333
0.93333333
0.85294118


chr16: 84519930
0.943015
73.3333333
0.875
0.91176471


chr8: 58989473
0.94246
92.2619048
0.85714286
0.91666667


chr18: 27786294
0.941176
14.5511785
0.85714286
0.91176471


chr20: 22557408
0.940541
60.2564103
0.8
1


chr9: 128177708
0.940045
80.7608696
0.92307692
0.85294118


chr7: 157633760
0.939394
68.3333333
0.92307692
0.96969697


chr6: 40349351
0.9375
21.5384615
0.8125
0.97142857


chr6: 157229362
0.937255
5.90277778
0.93333333
0.91176471


chr13: 84927994
0.937229
79.3800539
1
0.81818182


chr4: 8101279
0.935556
28.0359435
0.8
1


chr22: 41667328
0.934743
15.8874459
1
0.82352941


chr5: 176843804
0.931985
64.6428571
0.9375
0.76470588


chr5: 176529007
0.931373
62.8787879
0.93333333
0.88235294


chr4: 137426451
0.930804
94.567355
1
0.84375


chr6: 40349318
0.930796
80.5405405
0.94117647
0.82352941


chr11: 11578650
0.930303
29.1509084
0.86666667
0.87878788


chr20: 20364628
0.92963
2.43313796
0.93333333
0.83333333


chr6: 40349319
0.929464
71.4884021
0.875
0.91428571


chr17: 48190199
0.929412
83.9893617
0.86666667
0.91176471


chr7: 100122301
0.929412
18.7575758
0.93333333
0.82352941


chr1: 226589216
0.929333
72.0779221
0.8
0.92


chr22: 40022901
0.929167
89.4444444
0.93333333
0.84375


chr6: 37078047
0.929167
82.8008361
0.93333333
0.84375


chr9: 134765725
0.927619
64.4957983
0.86666667
0.82857143


chr20: 20364641
0.926667
11.673699
0.8
0.94285714


chr18: 77020770
0.926573
84.4129555
0.92307692
0.84848485


chr17: 3695881
0.926563
13.3928571
0.9
0.90625


chr19: 38253123
0.92562
68.115942
0.90909091
0.86363636


chr9: 114255802
0.92542
83.952381
0.92857143
0.85294118


chr7: 157017749
0.925408
21.1929825
0.77272727
0.97435897


chr17: 74823356
0.925325
91.6666667
0.95238095
0.77272727


chr9: 117355642
0.92435
78.8353863
0.88888889
0.85106383


chr6: 51213976
0.924107
36.6666667
1
0.8


chr7: 151045548
0.923197
35.1470588
0.81818182
0.93103448


chr16: 4537495
0.923077
31.423959
0.875
0.8974359


chr2: 45274755
0.923021
15.2413793
0.77777778
0.94117647


chr8: 139674518
0.922857
65.3966132
0.8
0.94285714


chr12: 132134577
0.922727
6.2745098
0.90909091
0.86666667


chr9: 134885740
0.922549
33.7912088
0.93333333
0.82352941


chr16: 4537572
0.922323
18.5714286
0.82352941
0.94871795


chr17: 1961091
0.922269
15.0987654
0.92857143
0.88235294


chr6: 51213977
0.921569
22.5
0.93333333
0.79411765


chr11: 888785
0.921512
95.7427536
0.95
0.76744186


chr9: 134815626
0.92128
48.3050847
0.88235294
0.88235294


chr13: 110011941
0.920507
84.6978558
0.85714286
0.90322581


chr19: 13372294
0.920202
99.1803279
1
0.75757576


chr16: 84519955
0.920037
38.3390706
1
0.73529412


chr20: 20364626
0.92
6.9047619
0.86666667
0.88571429


chr20: 20364640
0.919444
5.15898767
0.93333333
0.83333333


chr17: 57874806
0.919255
86.2997658
0.91304348
0.82857143


chr6: 168638634
0.919118
91.4285714
1
0.76470588


chr7: 14372215
0.919118
55.8333333
0.78571429
0.97058824


chr22: 50010360
0.918919
81.5340909
0.88888889
0.86486486


chr14: 56814573
0.918627
78.8888889
0.8
0.88235294


chr13: 112641259
0.918168
84.3171296
0.83333333
0.89189189


chr7: 146633722
0.917708
90.8902692
0.86666667
0.875


chr7: 157633743
0.917647
73.5431235
0.86666667
0.97058824


chr21: 43758530
0.917647
60.2941176
0.93333333
0.82352941


chr6: 168538915
0.917647
68.0489102
0.93333333
0.73529412


chr5: 176843791
0.917279
53.9130435
0.75
0.97058824


chr2: 46983311
0.917094
89.039039
0.88461538
0.88888889


chr2: 239300749
0.91619
89.6969697
0.93333333
0.8


chr7: 157998148
0.915966
83.974359
1
0.73529412


chr6: 34128215
0.915686
94.0972222
0.93333333
0.82352941


chr13: 112106712
0.915584
62.8101402
0.85714286
0.84848485


chr16: 3999700
0.915179
70.5627706
0.82142857
0.89583333


chr9: 114172063
0.915179
51.8154762
1
0.75


chr9: 134792142
0.915179
45.1548452
0.85714286
0.90625


chr11: 11578688
0.915152
74.7364458
0.86666667
0.87878788


chr7: 157833048
0.914815
71.1708566
0.8
1


chr1: 151346323
0.914643
56.9385593
0.78571429
0.92


chr21: 38661697
0.914469
55.2811245
0.93103448
0.80392157


chr1: 226588954
0.91413
73.8636364
0.86956522
0.875


chr20: 6232329
0.914063
85.4166667
0.9
0.78125


chr9: 134792130
0.914063
12.4620061
1
0.71875


chr9: 134785070
0.91342
57.4786325
0.78571429
0.90909091


chr9: 134815627
0.913265
33.7108014
1
0.71428571


chr9: 134592825
0.913131
16.025641
1
0.78787879


chr16: 84519980
0.912879
42.0168067
0.9375
0.84848485


chr7: 100122290
0.912745
29.1666667
0.93333333
0.85294118


chr11: 11973687
0.912587
83.974359
0.92307692
0.78787879


chr19: 38253193
0.912482
71.9362219
1
0.70731707


chr14: 44405368
0.912338
78.030303
0.92857143
0.81818182


chr16: 4260161
0.91226
80.3846154
0.92307692
0.875


chr2: 28411073
0.912121
90.9459459
0.86666667
0.84848485


chr1: 50214861
0.912103
72.6370045
0.82758621
0.82352941


chr16: 84519943
0.911932
42.481203
0.9375
0.84848485


chr22: 19933408
0.911828
76.0714286
0.86666667
0.90322581


chr11: 68833022
0.911765
82.8431373
0.93333333
0.73529412


chr7: 73985377
0.911765
56.684492
1
0.82352941


chr9: 93014375
0.911765
63.3971292
0.78571429
0.91176471


chr9: 114183920
0.911765
43.9613527
1
0.73529412


chr16: 4260632
0.911585
8.71212121
0.95
0.75609756


chr9: 133558991
0.910985
72.2128378
0.91666667
0.88636364


chr6: 168638701
0.910784
64.3483023
0.86666667
0.88235294


chr7: 157658598
0.910784
82.2727273
0.73333333
0.97058824


chr19: 13506729
0.910204
88.1944444
0.92857143
0.85714286


chr19: 13483181
0.910101
94.4698703
0.86666667
0.84848485


chr16: 84519942
0.909926
72.7018482
0.875
0.88235294


chr11: 76784947
0.909903
57.5268817
0.82142857
0.88636364


chr11: 65551424
0.909804
25.9109312
0.86666667
0.82352941


chr7: 2193699
0.909804
79.5138889
0.8
0.91176471


chr5: 179258981
0.909677
45.1923077
1
0.67741935


chr14: 99518884
0.909664
52.1492921
0.71428571
0.97058824


chr18: 27786301
0.909664
8.16056191
0.92857143
0.85294118


chr11: 64056580
0.909659
88.4277466
0.8
0.86363636


chr6: 169251928
0.909399
72.3011364
0.83333333
0.93023256


chr9: 134486435
0.909314
93.0952381
0.75
0.94117647


chr12: 132134595
0.909091
11.6161616
0.9375
0.81818182


chr16: 84519935
0.909091
64.1025641
0.8125
0.93939394


chr21: 41179996
0.909091
83.1300813
0.8
0.90909091


chr14: 105392911
0.908929
93.9338235
0.9
0.89285714


chr7: 40330569
0.908824
16.7582298
0.86666667
0.85294118


chr13: 111622152
0.908669
88.5620915
1
0.81578947


chr2: 98823202
0.908547
94.6778711
1
0.69230769


chr17: 29972557
0.908179
43.1354515
1
0.77777778


chr9: 134815918
0.908163
54.4230769
1
0.77142857


chr1: 213905614
0.908152
81.8910256
0.91304348
0.825


chr7: 2607131
0.908027
91.2878788
0.84615385
0.84782609


chr4: 8101234
0.907867
85.7843137
0.85714286
0.82608696


chr12: 103012503
0.907778
41.2235009
0.81481481
0.84


chr14: 44262090
0.907563
88.7778412
1
0.76470588


chr6: 82363058
0.907482
32.3643411
0.91304348
0.86046512


chr9: 114170339
0.907121
46.547619
0.94117647
0.78947368


chr6: 168138608
0.907051
89.1812865
1
0.71794872


chr12: 11856447
0.906926
44.8538012
0.92857143
0.81818182


chr19: 13634667
0.906863
90.6926407
0.86666667
0.85294118


chr9: 93722421
0.906863
91.6083916
0.93333333
0.76470588


chr9: 114172123
0.906863
35.7336957
1
0.73529412


chr17: 29565848
0.906746
18.2623049
0.85714286
0.94444444


chr11: 64353390
0.906636
10.7526882
1
0.72222222


chr9: 90908530
0.906452
83.974359
1
0.70967742


chr16: 3999757
0.906071
80.7539683
1
0.74


chr11: 65551425
0.905882
16.5906128
1
0.70588235


chr9: 114306707
0.905754
16.4351852
1
0.72222222


chr19: 2354863
0.905556
91.9047619
0.93333333
0.80555556


chr9: 136289024
0.905405
19.7374897
0.8125
0.91891892


chr6: 107633714
0.905051
90.4157858
0.86666667
0.93939394


chr7: 157017791
0.905012
12.2360248
0.86363636
0.92307692


chr6: 168496984
0.904977
81.5104167
0.84615385
0.91176471


chr3: 45819148
0.904902
93.4443657
0.93333333
0.73529412


chr18: 77102188
0.904429
72.5694444
0.76923077
0.93939394


chr12: 105784446
0.904327
65.04329
0.75862069
0.92156863


chr17: 29972550
0.904321
60.4347826
0.83333333
0.86111111


chr11: 119702010
0.903922
41.0441044
0.8
0.85294118


chr5: 1316124
0.903922
0.28409091
0.93333333
0.76470588


chr7: 73966925
0.90368
70.5300128
0.78571429
0.90909091


chr3: 53702765
0.90368
94.7222222
0.92857143
0.81818182


chr11: 118924054
0.903646
52.2727273
0.91666667
0.90625


chr19: 51077543
0.903333
56.4705882
0.8
0.93333333


chr17: 81246338
0.902902
75.5555556
0.92857143
0.8125


chr12: 3077928
0.902872
22.5396825
0.96296296
0.75510204


chr12: 130460997
0.902748
56.25
0.81818182
0.95348837


chr7: 157963798
0.902715
88.1818182
0.92307692
0.79411765


chr12: 130483815
0.902597
90.6445993
0.85714286
0.87878788


chr7: 157963771
0.902344
88.3116883
0.91666667
0.875


chr14: 64942593
0.901961
52.7525711
0.86666667
0.88235294


chr18: 59203056
0.901961
92.5824176
0.86666667
0.91176471


chr19: 13463517
0.901961
82.8571429
0.86666667
0.88235294


chr20: 20364646
0.901852
18.079096
0.73333333
1


chr7: 157987469
0.901852
88.75
0.8
0.94444444


chr2: 216380208
0.901786
43.75
0.8125
0.91428571


chr20: 16806905
0.901681
90.8033827
0.82352941
0.8


chr17: 74961041
0.901515
73.2142857
0.81818182
1


chr3: 176190636
0.901182
91.2878788
0.75
0.94594595


chr20: 22652824
0.901087
80.1960784
0.95652174
0.8


chr6: 37078083
0.901075
72.4747475
1
0.67741935


chr14: 44405319
0.901042
63.0681818
0.8
0.9375


chr18: 72677631
0.901042
92.1212121
0.875
0.86111111


chr9: 136686592
0.90101
20.5263158
0.93333333
0.78787879


chr2: 216986073
0.900735
15.0565262
0.8125
0.91176471


chr2: 10040203
0.900538
63.8181818
0.83333333
0.87096774


chr21: 38636406
0.900483
83.1140351
1
0.64444444


chr9: 134824994
0.900433
79.2857143
0.92857143
0.78787879


chr12: 119158214
0.900426
73.7068966
0.8
0.89361702


chr7: 5795946
0.900293
15.7407407
0.90909091
0.80645161


chr22: 19933350
0.90021
42.1296296
0.92857143
0.82352941


chr9: 134785048
0.90021
84.1085271
1
0.79411765


chr13: 111559772
0.9
85.9895484
0.92857143
0.83333333


chr16: 88640994
0.9
65.6862745
0.8
0.90909091


chr17: 29972549
0.9
62.7815315
0.86666667
0.85714286


chr6: 168130574
0.9
85.9342302
0.86666667
0.82352941


chr6: 168130602
0.9
98.4115884
0.93333333
0.73529412


chr9: 114183394
0.9
52.6129032
0.78571429
0.88


chr9: 120326115
0.9
91.2878788
0.85
0.87804878


chr3: 177516507
0.899909
83.4094803
0.75
0.91304348


chr7: 110084403
0.899767
77.3504274
0.84615385
0.87878788


chr22: 50010361
0.899729
72.0486111
0.77777778
0.87804878


chr18: 76681573
0.899671
91.9871795
0.9375
0.76315789


chr7: 158485004
0.89946
91.0199005
0.78947368
0.94871795


chr21: 38661630
0.899052
48.3333333
0.78571429
0.85714286


chr15: 53659351
0.899038
6.51260504
0.84615385
0.90625


chr19: 13347369
0.89902
80.8035714
0.73333333
0.97058824


chr19: 39163809
0.89902
84.2588446
0.93333333
0.91176471


chr17: 48620272
0.89899
60.4264292
0.8
0.90909091


chr18: 71652249
0.89899
38.1048387
0.86666667
0.90909091


chr6: 168667391
0.89899
91.9871795
0.86666667
0.81818182


chr10: 133309889
0.898966
14.7186147
0.79310345
0.88


chr1: 241210311
0.898864
81.4381271
0.8
0.93181818


chr19: 46770637
0.89881
13.8095238
0.82142857
0.8627451


chr20: 22556743
0.898649
66.1714771
0.8
0.94594595


chr2: 47227055
0.898571
20.8695652
0.78571429
0.92


chr7: 150974698
0.898485
17.1568627
0.81818182
0.9


chr20: 22653042
0.898438
56.547619
0.79166667
0.925


chr14: 73228468
0.898311
40.9803922
0.75862069
0.91836735


chr19: 18422970
0.898295
89.2045455
0.86363636
0.8


chr21: 40144935
0.898095
88.6752137
0.8
0.94285714


chr16: 85355024
0.898039
70.8333333
0.8
0.94117647


chr19: 13575256
0.898039
11.0357242
0.86666667
0.91176471


chr9: 134690692
0.897917
57.7380952
1
0.75


chr6: 82363052
0.897877
41.7774086
0.91304348
0.8372093


chr7: 122307220
0.897771
69.0981432
0.95833333
0.74418605


chr7: 157633801
0.897436
60.7669617
0.84615385
1


chr1: 43439683
0.897059
80.9428785
0.86666667
0.91176471


chr16: 64387
0.897059
10.6442577
1
0.64705882


chr2: 216986079
0.897059
13.1642512
0.875
0.85294118


chr9: 134885778
0.897059
15.4061625
1
0.73529412


chr4: 128846433
0.89697
17.9006731
0.93333333
0.6969697


chr1: 43550363
0.896552
3.92307692
1
0.65517241


chr3: 9180988
0.896552
75.3571429
0.86206897
0.83333333


chr19: 511219
0.896465
17.1428571
0.83333333
0.96969697


chr20: 62711715
0.896104
36.9318182
0.90909091
0.96428571


chr11: 47327260
0.896078
85.1648352
0.8
0.97058824


chr6: 51214001
0.896078
15.7960199
0.8
0.88235294


chr5: 10652237
0.89596
92.5824176
0.93333333
0.75757576


chr4: 6944534
0.895946
83.4841629
0.95
0.81081081


chr21: 38599607
0.895833
84.5238095
0.86666667
0.875


chr6: 168440545
0.895833
72.6775956
1
0.69444444


chr1: 18794157
0.895833
13.8095238
0.91666667
0.78125


chr8: 52150618
0.895433
53.2352941
0.84615385
0.84375


chr9: 133662377
0.895433
86.8055556
0.84615385
0.84375


chr16: 4537619
0.895349
35.8974359
0.76470588
0.93023256


chr19: 39307494
0.895221
14.7157191
0.8125
0.94117647


chr19: 55254005
0.895098
49.7917751
0.86666667
0.85294118


chr12: 130535047
0.895098
94.5588235
0.8
0.94117647


chr5: 82804
0.895098
89.8989899
1
0.70588235


chr6: 34128233
0.895098
99.6453901
0.93333333
0.76470588


chr12: 11856451
0.895022
61.2979506
0.85714286
0.84848485


chr19: 13506452
0.894792
41.7867147
0.8
0.9375


chr17: 77452817
0.894737
87.0833333
0.94736842
0.77777778


chr6: 109290309
0.894643
83.5888975
0.8125
0.91428571


chr21: 38661664
0.894523
59.2451144
0.96551724
0.80392157


chr10: 133309857
0.894483
7.91637303
0.89655172
0.78


chr21: 34667592
0.894271
71.4052288
0.85
0.83333333


chr7: 100477920
0.894231
87.8676471
0.84615385
0.8125


chr20: 38294975
0.894118
84.3939394
0.8
0.94117647


chr21: 41648785
0.894118
81.9642857
0.8
0.85294118


chr21: 43758525
0.894118
71.657754
0.93333333
0.79411765


chr9: 134822835
0.894044
14.5104895
0.94736842
0.76315789


chr16: 3728390
0.893599
99.2537313
0.82352941
0.91176471


chr16: 29604945
0.893571
73.2924869
0.89285714
0.82


chr1: 41727346
0.893534
84.1995842
0.91304348
0.69230769


chr21: 45032479
0.893382
45.2586207
0.75
0.94117647


chr1: 39954061
0.893333
95.9166667
1
0.7


chr17: 29972554
0.893333
39.8026316
1
0.71428571


chr6: 151809197
0.893333
43.1272727
0.86666667
0.82857143


chr12: 111287675
0.893189
38.962766
0.76470588
0.86842105


chr19: 13463510
0.893137
82.0855615
0.93333333
0.70588235


chr8: 52150574
0.893029
71.6402116
0.69230769
0.96875


chr19: 13014442
0.892929
55.1547988
0.66666667
1


chr4: 8164496
0.892929
84.3076923
1
0.66666667


chr7: 8417325
0.892929
90.7670455
0.93333333
0.75757576


chr7: 157673872
0.892857
70.8333333
0.78571429
0.90909091


chr2: 107461969
0.892857
85.1648352
0.92857143
0.71875


chr9: 36781051
0.892857
88.1944444
0.91666667
0.80952381


chr4: 138912435
0.892593
12.9935721
0.8
0.94444444


chr7: 157594362
0.892593
94.2222222
0.86666667
0.83333333


chr2: 237733847
0.892424
83.6666667
0.81818182
0.86666667


chr20: 22652808
0.892391
34.2032967
0.82608696
0.9


chr14: 64942648
0.892157
65.6698565
0.8
0.88235294


chr16: 4260588
0.892073
15.4019926
0.95
0.7804878


chr7: 157603987
0.891964
73.3766234
0.6875
0.97142857


chr7: 157540317
0.891892
93.2126697
0.86666667
0.78378378


chr13: 111515678
0.891882
80.2269571
0.93103448
0.72916667


chr17: 67488327
0.891775
72.0688869
0.92857143
0.78787879


chr7: 73990185
0.891775
66.5994624
0.92857143
0.78787879


chr10: 43849791
0.891705
29.6703297
0.92857143
0.77419355


chr17: 1961149
0.891667
27.7140335
0.86666667
0.875


chr6: 82585382
0.891176
56.6964286
0.86666667
0.85294118


chr1: 224184849
0.891176
92.0254058
0.86666667
0.79411765


chr2: 182053988
0.891141
89.1812865
0.94444444
0.75675676


chr21: 41508507
0.890977
42.2619048
0.94736842
0.73809524


chr15: 85942771
0.890909
90.4545455
0.8
0.90909091


chr10: 78139388
0.890741
85.3571429
0.95
0.66666667


chr9: 126420967
0.890704
5.84381551
0.92592593
0.76470588


chr15: 67806290
0.890625
82.8431373
0.8
0.84375


chr7: 157963797
0.890625
78.4161491
0.83333333
0.9375


chr9: 113593968
0.890625
73.8636364
1
0.71875


chr7: 157875450
0.890196
78.3625731
0.8
0.94117647


chr7: 157875495
0.890196
62.6409018
0.86666667
0.85294118


chr14: 64942637
0.890196
19.6275946
0.86666667
0.79411765


chr19: 55254025
0.890196
47.2463768
0.93333333
0.82352941


chr1: 205447752
0.890152
56.4144737
0.83333333
0.84848485


chr16: 84519956
0.890152
56.9444444
0.875
0.81818182


chr9: 134797123
0.889889
40.6896552
1
0.68421053


chr18: 63207225
0.889706
16.8640183
0.8125
0.91176471


chr9: 134772536
0.88952
69.6691176
0.95454545
0.69444444


chr8: 38495018
0.889452
89.3820225
0.86206897
0.76470588


chr13: 112107447
0.889401
89.4444444
0.92857143
0.74193548


chr5: 100864671
0.889368
86.6071429
0.75
0.93103448


chr14: 91418510
0.889286
1.26814388
0.875
0.82857143


chr9: 134768753
0.889277
70.3546454
0.84615385
0.87878788


chr19: 13245332
0.889247
89.5121951
0.93333333
0.83870968


chr11: 47327256
0.889216
46.1757991
0.93333333
0.79411765


chr8: 42275934
0.889216
92.7248677
0.86666667
0.79411765


chr12: 103165897
0.889205
91.8103448
0.75
1


chr18: 38714972
0.88914
26.6666667
0.69230769
1


chr7: 157824560
0.888889
52.7777778
0.86666667
0.84848485


chr14: 75978696
0.888889
77.7472527
0.96153846
0.75555556


chr15: 40873466
0.888889
29.1503268
0.85185185
0.81632653


chr4: 104663323
0.888889
88.1944444
0.94444444
0.74285714


chr5: 1316150
0.888655
3.00975709
0.85714286
0.91176471


chr4: 189096959
0.888571
87.8676471
0.8
0.85714286


chr9: 134750430
0.888571
81.3186813
1
0.77142857


chr13: 98405890
0.888542
30.2419355
0.8
0.90625


chr9: 134825870
0.888386
38.3152174
0.88235294
0.74358974


chr16: 52621839
0.888235
60.8152174
0.93333333
0.82352941


chr17: 62653135
0.888235
0.24769007
0.86666667
0.85294118


chr9: 134881575
0.888235
25.8333333
0.86666667
0.82352941


chr7: 157633794
0.888112
53.6873156
0.84615385
1


chr9: 114170237
0.8881
74.5726496
0.82758621
0.8627451


chr18: 77020828
0.888009
85.1648352
0.92307692
0.70588235


chr2: 216840164
0.887955
93.0952381
0.92857143
0.7254902


chr2: 181684626
0.887879
71.1111111
1
0.72727273


chr9: 134819274
0.887879
79.1666667
0.93333333
0.78787879


chr21: 34743983
0.887771
73.4408602
0.94117647
0.73684211


chr17: 57874702
0.887762
35.4761905
0.62068966
1


chr22: 28923959
0.887534
4.63800905
0.94444444
0.73170732


chr21: 44698714
0.88748
88.7152778
0.92307692
0.78723404


chr11: 65551324
0.887424
12.2222222
0.72413793
0.92156863


chr9: 113593972
0.887273
71.8253968
0.76
0.90909091


chr7: 2193759
0.887255
81.6498316
0.73333333
0.94117647


chr6: 168440498
0.887122
10.7736761
0.70588235
0.94594595


chr8: 141264221
0.887037
66.9871795
0.92592593
0.8


chr16: 4260115
0.887019
86.2229102
0.92307692
0.8125


chr16: 4537502
0.887019
71.8253968
0.8125
0.82051282


chr20: 20365491
0.886997
7.70308123
1
0.73684211


chr1: 7491237
0.886869
22.9223901
0.86666667
0.93939394


chr20: 20364647
0.886667
1.2112473
0.86666667
0.82857143


chr11: 31893506
0.886555
58.9285714
1
0.73529412


chr19: 41704632
0.886555
58.3751793
0.92857143
0.76470588


chr20: 17068564
0.886555
66.3531998
0.71428571
0.94117647


chr5: 6543207
0.886555
78.8888889
0.78571429
0.88235294


chr19: 41323849
0.886458
47.7272727
1
0.6875


chr2: 85733778
0.886458
79.3706294
0.79166667
0.9


chr7: 157685012
0.886409
75.7440476
0.875
0.78571429


chr11: 75240135
0.886364
78.4722222
0.85714286
0.90909091


chr6: 168315218
0.886305
43.2748538
0.74074074
0.90697674


chr14: 64633473
0.886285
85.2429297
0.875
0.80555556


chr11: 20056293
0.886275
40.5882353
0.86666667
0.91176471


chr14: 44379797
0.886161
75.7019969
0.85714286
0.8125


chr16: 4537618
0.886029
30.075188
0.82352941
0.9


chr7: 157864088
0.886029
74.9285714
0.75
0.94117647


chr10: 133309864
0.885862
8.86958387
0.86206897
0.8


chr14: 88256419
0.885859
94.5906433
0.93333333
0.81818182


chr16: 19425106
0.885859
37.9734848
0.73333333
0.96969697


chr6: 168355227
0.885835
79.4736842
0.77272727
0.93023256


chr9: 134765734
0.885714
64.4736842
1
0.77142857


chr6: 168453036
0.885714
71.9607843
0.86666667
0.8


chr21: 41490949
0.88558
31.8181818
0.72727273
0.93103448


chr7: 73989381
0.885504
28.507384
0.92857143
0.79411765


chr12: 3077894
0.885488
33.0265685
0.92592593
0.79591837


chr1: 53462420
0.885417
89.8989899
0.875
0.81818182


chr9: 113593928
0.885417
86.6071429
0.86666667
0.78125


chr10: 133309740
0.885326
36.161435
0.69565217
0.95


chr7: 101666174
0.885294
44.077621
0.86666667
0.82352941


chr11: 14974476
0.885045
74.7727273
0.92857143
0.78125


chr5: 100944956
0.884848
66.9642857
0.73333333
0.96969697


chr20: 22557482
0.884821
85.4152824
0.875
0.91428571


chr18: 74782855
0.884615
91.1067194
0.72727273
1


chr19: 3656386
0.884444
92.5824176
0.81481481
0.88


chr7: 26397761
0.884375
64.3858478
0.8
0.9375


chr19: 13463491
0.884314
67.556719
0.8
0.85294118


chr22: 38087144
0.884314
75
0.73333333
0.91176471


chr9: 130535984
0.884314
0.93338069
0.93333333
0.85294118


chr9: 134892203
0.884314
35.4444444
1
0.67647059


chr13: 107429178
0.884199
94.3939394
0.85714286
0.81818182


chr19: 38253194
0.884199
39.8275862
0.76190476
0.90909091


chr17: 82078952
0.884164
82.5757576
0.81818182
0.87096774


chr1: 1174126
0.883987
94.6428571
0.94117647
0.75


chr1: 232307467
0.883929
85.4497354
1
0.71875


chr6: 14499964
0.883929
66.9642857
0.91666667
0.89285714


chr16: 4260566
0.883657
32.7380952
0.78947368
0.89473684


chr16: 85286422
0.883556
99.4897959
0.92
0.77777778


chr17: 74006568
0.883553
81.9293478
0.8
0.86842105


chr7: 101707772
0.883523
15.6923077
1
0.84375


chr6: 168496991
0.883484
77.7047414
0.84615385
0.91176471


chr18: 27786339
0.883403
14.9339301
0.78571429
0.85294118


chr13: 113793557
0.883333
92.9802956
0.93333333
0.8


chr19: 47209566
0.883333
84.5
0.86666667
0.85294118


chr2: 113325550
0.883333
59.8039216
0.8
0.85294118


chr5: 176529022
0.883333
89.1176471
0.86666667
0.79411765


chr8: 52150549
0.883333
83.75
0.8
0.94117647


chr9: 113594013
0.883182
49.3589744
0.84
0.81818182


chr9: 134490841
0.883117
86.0576923
0.85714286
0.90909091


chr7: 1620862
0.883108
57.6705882
0.7
0.97297297


chr9: 134179005
0.883107
15.5152672
0.94117647
0.87179487


chr15: 63053313
0.882883
76.6304348
0.77777778
0.94594595


chr12: 124617614
0.882828
20.7142857
0.93333333
0.72727273


chr21: 45032480
0.882828
57.5554773
0.73333333
0.93939394


chr13: 113723025
0.882813
58.4770115
0.92857143
0.71875


chr7: 150945169
0.882813
76.3888889
0.9375
0.75


chr12: 6961918
0.882796
8.39160839
0.8
0.90322581


chr19: 39307859
0.882407
16.2280702
0.875
0.8


chr16: 89948104
0.882353
1.77343619
0.88235294
0.78787879


chr19: 8153491
0.882353
56.9354839
0.73333333
0.91176471


chr20: 20365487
0.882353
8.11688312
0.94117647
0.73684211


chr20: 38294974
0.882353
68.627451
0.8
0.85294118


chr3: 73790643
0.882353
92.3001311
0.92857143
0.73529412


chr6: 153237290
0.882353
67.6435407
0.73333333
0.91176471


chr6: 168130594
0.882353
83.7985742
0.8
0.94117647


chr7: 2524564
0.882353
15.7198306
0.8
0.88235294


chr9: 134785301
0.882353
67.9487179
0.94117647
0.8


chr9: 136367817
0.882353
52.7777778
0.86206897
0.80392157


chr19: 38253176
0.882325
43.4734735
0.86956522
0.7826087


chr19: 406561
0.882212
86.6071429
0.92307692
0.8125


chr1: 52633297
0.882143
6.94444444
0.8
0.92857143


chr9: 93819344
0.882125
80.9975603
0.72413793
0.97959184


chr11: 76784948
0.882102
49.2424242
0.83333333
0.86363636


chr14: 36524358
0.882086
72.4747475
0.85185185
0.81632653


chr13: 112106739
0.882035
87.75
0.92857143
0.78787879


chr6: 157228665
0.8819
80.2175665
0.78947368
0.87804878


chr7: 157953525
0.881875
77.3504274
0.85
0.85


chr10: 101780858
0.881818
91.2878788
0.86666667
0.78787879


chr12: 110942244
0.881818
35.4166667
0.86666667
0.87878788


chr6: 43578006
0.881766
95.5824972
0.94444444
0.71794872


chr2: 51027486
0.88172
97.4804382
0.93333333
0.77419355


chr7: 157685871
0.881506
62.5567151
0.71428571
1


chr21: 45032448
0.881434
40.3947368
0.75
0.91176471


chr21: 45032452
0.881434
59.8684211
0.75
0.88235294


chr7: 157017829
0.881422
17.3118548
0.75862069
0.89795918


chr11: 65551413
0.881373
44.5175439
0.73333333
0.91176471


chr7: 157544388
0.881303
84.8739496
0.78571429
0.91176471


chr6: 50845964
0.881222
47.8103176
0.84615385
0.85294118


chr5: 138650055
0.881169
73.6111111
0.86363636
0.8


chr1: 229147368
0.881081
88.4444444
0.86666667
0.83783784


chr9: 134782536
0.881076
19.375
0.95833333
0.79166667


chr9: 134316337
0.880878
82.2134387
1
0.65517241


chr12: 124259764
0.880831
30.2173913
0.82142857
0.85714286


chr11: 11578685
0.880808
75.1282051
0.93333333
0.81818182


chr20: 17068489
0.880808
94.8684211
0.86666667
0.84848485


chr20: 20365493
0.880805
4.23280423
1
0.73684211


chr22: 28923940
0.880759
9.90338164
0.83333333
0.87804878


chr22: 28923966
0.880759
15.0323774
0.77777778
0.87804878


chr1: 153536136
0.880682
1.61290323
0.90909091
0.75


chr9: 93861253
0.880435
85.1648352
0.8
0.91304348


chr11: 64540473
0.880392
47.7272727
0.73333333
0.91176471


chr2: 229672283
0.880392
59.6590909
0.86666667
0.79411765


chr7: 157633759
0.880392
74.2946708
0.86666667
0.91176471


chr9: 134534796
0.880392
43.0262046
0.86666667
0.85294118


chr9: 114170276
0.880342
27.5362319
1
0.71794872


chr19: 5950505
0.880303
89.1812865
0.72727273
0.93333333


chr1: 32885121
0.880252
32.0512821
0.64285714
0.97058824


chr12: 6962651
0.880252
7.10784314
0.85714286
0.76470588


chr18: 27786338
0.880252
16.5158371
0.92857143
0.79411765


chr18: 63207261
0.880252
7.73809524
0.85714286
0.82352941


chr19: 41704681
0.880252
23.4280792
0.78571429
0.91176471


chr8: 141289585
0.880252
62.5874126
0.78571429
1


chr11: 124895535
0.880208
40.8730159
0.95833333
0.75


chr17: 57874844
0.880124
66.2284546
0.7826087
0.91428571


chr11: 75335191
0.88
71.7482517
0.67857143
0.98


chr18: 71337086
0.88
11.1742424
0.86666667
0.8


chr2: 46983412
0.879939
84.6989967
0.89285714
0.85106383


chr1: 212589163
0.87987
42.1296296
0.85714286
0.81818182


chr20: 48751499
0.87987
59.0909091
0.85714286
0.81818182


chr4: 78056611
0.879798
0.67241038
0.86666667
0.84848485


chr3: 176814702
0.879658
86.6025641
0.78571429
0.93478261


chr17: 81246299
0.879639
81.3852814
0.7826087
0.92682927


chr2: 3940818
0.879596
40.5837344
0.75
0.97058824


chr12: 98238503
0.879583
81.4646465
0.8
0.875


chr9: 114170300
0.879487
50.228833
0.93333333
0.71794872


chr11: 924647
0.879424
81.9264069
0.88888889
0.84444444


chr19: 55254024
0.879412
46.1061947
0.86666667
0.79411765


chr2: 208703401
0.879412
84.8728814
0.86666667
0.82352941


chr20: 22598941
0.879412
92.2619048
0.8
0.91176471
















TABLE 28







DNA methylation sites associated with SCLC-N











MethylationSite
AUC
threshold
specificity
sensitivity














chr1:54356529
1
7.56298908
1
1


chr1:109296245
1
66.0714286
1
1


chr1:109296247
1
78.021978
1
1


chr1:220653171
1
48.9473684
1
1


chr1:220653195
1
53.5028249
1
1


chr11:35853956
1
69.047619
1
1


chr11:64154503
1
37.0689655
1
1


chr11:64154571
1
52.8287462
1
1


chr11:64154574
1
68.75
1
1


chr12:108792675
1
60.3896104
1
1


chr17:72440313
1
32.0175439
1
1


chr17:72440361
1
43.3035714
1
1


chr2:223901322
1
60.4609929
1
1


chr20:19919227
1
59.6972564
1
1


chr3:52468694
1
44.5856354
1
1


chr5:160245925
1
26.3241625
1
1


chr6:44261803
1
68.1818182
1
1


chr8:42275934
1
70.5376344
1
1


chr9:131721310
1
34.5744681
1
1


chr9:131721341
1
72.3169192
1
1


chr9:131721355
1
28.125
1
1


chr9:131721389
1
61.030303
1
1


chr2:216909627
0.998476
43.9102564
0.97560976
1


chr20:19919173
0.996951
58.5885886
0.97560976
1


chr9:131721356
0.996951
51.8405797
0.97560976
1


chr22:50276667
0.996795
63.3012821
0.97435897
1


chr17:72440360
0.996711
46.422956
0.97368421
1


chr6:37537738
0.996599
28.5714286
0.97619048
1


chr1:220653165
0.996516
55.6140351
0.97560976
1


chr1:220653180
0.996516
58.245614
0.97560976
1


chr8:140270696
0.996516
63.8045541
0.97560976
1


chr12:108792684
0.996429
74.6031746
0.975
1


chr19:3656274
0.995556
59.1269841
0.95555556
1


chr1:54356527
0.995192
7.07146427
0.97435897
1


chr19:47650943
0.995192
70.375
0.97435897
1


chr7:149261799
0.995098
12.1428571
0.97058824
1


chr2:216380208
0.994709
23.5429448
0.95238095
1


chr17:72440372
0.993902
21.8781598
0.97560976
1


chr9:131721340
0.993902
87.9503546
0.95121951
1


chr9:131721342
0.993902
87.3670213
0.95121951
1


chr2:216380274
0.99375
23.5663082
0.975
1


chr11:67493309
0.99359
79.5833333
0.94871795
1


chr2:65583301
0.993243
71.0164835
0.94594595
1


chr5:160245988
0.993243
47.7272727
0.94594595
1


chr3:52468622
0.992674
50
0.94871795
1


chr17:74823299
0.992593
86.0576923
0.95555556
1


chr1:160362850
0.992188
23.8636364
0.95
1


chr12:31009628
0.991071
35.625
0.92857143
1


chr14:64633473
0.990956
55
0.97674419
1


chr18:59049918
0.990854
18.414548
0.97560976
1


chr20:63878908
0.990854
62.6436782
0.92682927
1


chr5:16538225
0.990854
55.3655713
0.92682927
1


chr6:19719869
0.990854
56.7176871
0.92682927
1


chr6:34128215
0.990854
73.0952381
0.97560976
1


chr6:34128233
0.990854
79.1666667
0.97560976
1


chr1:109296235
0.990625
43.0960086
0.95
1


chr3:52522225
0.990625
39.3939394
0.95
1


chr8:134941130
0.990625
64.2857143
0.925
1


chr7:149261769
0.990196
30.3571429
0.97058824
1


chr19:3656352
0.990018
42.6406926
0.94827586
0.94736842


chr2:85733778
0.989987
58.7121212
0.95744681
0.94117647


chr4:850796
0.989286
85.2071006
0.925
1


chr3:126013960
0.988722
57.9831933
0.97368421
1


chr19:3655899
0.988372
32.8282828
0.93023256
1


chr22:44049853
0.988176
67.0192308
0.94594595
1


chr9:120242580
0.987879
46.9008264
0.95555556
1


chr1:41657833
0.987805
80.9090909
0.90243902
1


chr1:220653181
0.987805
82.5757576
0.90243902
1


chr11:8239208
0.987805
32.3643411
0.97560976
1


chr2:65583300
0.987805
61.7647059
0.95121951
1


chr5:16538207
0.987805
55.8731855
0.92682927
1


chr6:34128222
0.987805
73.8095238
0.97560976
1


chr9:131721343
0.987805
85.7777778
0.95121951
1


chr7:149261778
0.987745
38.0952381
0.94117647
1


chr14:105178678
0.9875
64.6381579
0.925
1


chr12:31009602
0.987179
38.1619938
0.97435897
1


chr1:28869236
0.986111
20.9183673
0.98275862
1


chr1:220653223
0.986063
82.3984526
0.90243902
1


chr7:44254153
0.986063
37.5718454
0.95121951
1


chr6:43475701
0.984756
26.2531861
0.97560976
1


chr15:68347588
0.984375
67.9060665
0.925
1


chr20:49345755
0.983232
16.3605642
0.97560976
1


chr5:160245950
0.983108
42.0761671
0.89189189
1


chr19:3656298
0.982222
67.4242424
0.93333333
1


chr19:3655920
0.981912
24.5384615
1
0.88888889


chr20:49345760
0.981707
17.8739348
0.95121951
1


chr6:34128216
0.981707
85.4166667
0.95121951
1


chr3:52468649
0.981685
33.7037037
0.97435897
1


chr1:944700
0.98125
12.7717391
0.9
1


chr1:54356503
0.98125
22.3680124
0.9
1


chr1:54356526
0.98125
20.11604
0.95
1


chr1:54356528
0.98125
21.4285714
0.925
1


chr2:216909691
0.98125
75.7142857
0.9
1


chr5:160245949
0.980769
15.6059768
1
0.875


chr21:41490949
0.980392
13.5714286
0.97058824
1


chr17:50076230
0.980263
64.9616368
0.94736842
1


chr2:25702014
0.979688
36.6898148
0.95
1


chr19:3655770
0.979167
57.4074074
0.92592593
1


chr9:120242557
0.979167
57.8495562
0.95833333
1


chr16:85439239
0.978723
60.8990148
0.89361702
1


chr1:53320062
0.978659
75.7142857
1
0.875


chr5:16538206
0.978659
29.3956044
1
0.875


chr6:19719865
0.978659
17.1929825
1
0.875


chr11:855989
0.978571
62.4675325
0.975
1


chr19:3655921
0.978405
43.9912281
0.88372093
1


chr6:107633786
0.97832
87.4632233
0.87804878
1


chr19:14182660
0.978125
73.7938596
0.9
1


chr19:48350598
0.978022
38.75
0.92307692
1


chr3:52468650
0.978022
15.7575758
0.97435897
1


chr16:10622418
0.977941
64.5833333
0.97058824
1


chr3:52468678
0.977564
46.3142219
0.92307692
1


chr11:20055879
0.977352
86.0062893
0.95121951
1


chr2:216909621
0.977134
74.6848739
0.90243902
1


chr6:34128193
0.977134
63.8713745
0.97560976
1


chr16:85287295
0.976916
70.3756881
0.85964912
1


chr1:53320061
0.976744
84.4129555
0.90697674
1


chr7:100890535
0.97619
28.7828947
0.97619048
1


chr12:48675723
0.97561
79.0117417
0.90243902
1


chr2:25701951
0.97561
83.1845238
0.87804878
1


chr20:63835624
0.97561
28.4090909
0.90243902
1


chr4:76612797
0.97561
69.6969697
0.95121951
1


chr6:43475769
0.97561
34.6153846
0.97560976
1


chr3:16132696
0.975
18.3969466
0.925
1


chr11:66866493
0.974359
24.1808133
0.94871795
0.9


chr12:31009572
0.974359
31.1121857
0.92307692
1


chr1:226588954
0.974069
67.3611111
0.87234043
1


chr16:66960251
0.973958
85.3571429
0.89583333
0.9375


chr19:3656369
0.973635
60.8242304
0.94915254
0.94444444


chr17:4809230
0.973545
52.8971029
0.88095238
1


chr7:157018053
0.973545
25.8333333
0.88095238
1


chr20:11271495
0.973238
67.4459459
0.88135593
1


chr17:82001560
0.973214
72.1153846
0.9047619
1


chr17:82001559
0.972561
85.1818182
0.87804878
1


chr2:85770228
0.972561
57.8703704
0.95121951
1


chr20:49345801
0.972561
26.2962963
0.90243902
1


chr21:41458778
0.972561
89.9541284
0.90243902
1


chr6:34128249
0.972561
94.2788686
0.87804878
1


chr11:44963230
0.972222
55.0480769
0.94827586
0.94444444


chr1:944730
0.971875
7.29166667
1
0.875


chr12:108792716
0.971875
71.7839375
0.9
1


chr22:44049787
0.971875
61.4709852
0.925
1


chr3:52522201
0.971875
79.1666667
0.925
1


chr4:6308154
0.971602
47.5334448
0.96551724
0.94117647


chr2:85733793
0.971214
50.1602564
0.93617021
0.94117647


chr19:12953781
0.971154
7.91105671
0.92307692
1


chr1:43550353
0.970588
88.75
0.94117647
1


chr21:41490965
0.970588
3.57142857
0.94117647
1


chr12:108792685
0.970313
86.1904762
0.875
1


chr3:16132702
0.970313
18.2194617
0.9
1


chr1:15723882
0.969925
67.0138889
0.86842105
1


chr1:54356555
0.969551
19.375
0.92307692
1


chr12:130484433
0.969512
35.0877193
0.92682927
1


chr17:4809161
0.969512
55.4824561
0.97560976
0.875


chr6:19719861
0.969512
34.4170772
0.97560976
0.875


chr6:26385134
0.969512
84.6927966
0.97560976
0.875


chr6:168130602
0.969512
82.8571429
0.95121951
1


chr19:13913675
0.969444
80.8823529
0.86666667
1


chr16:85287080
0.969298
29.5833333
0.8
1


chr11:888785
0.969231
91.9871795
0.82
1


chr19:3655898
0.968992
55.3977273
0.86046512
1


chr1:1921168
0.967949
67.4242424
0.84615385
1


chr2:200087052
0.967949
38.0986938
0.92307692
1


chr19:2354832
0.967901
90.1576684
0.82222222
1


chr11:129699789
0.967857
76.3931889
0.85
1


chr1:28869229
0.967433
43.6507937
0.94827586
1


chr19:18422970
0.967376
71.1111111
0.93617021
0.86666667


chr1:944737
0.967188
4.16666667
0.975
0.875


chr22:44049781
0.967188
68.9370485
0.9
1


chr20:25239829
0.966667
86.987782
0.91666667
0.94736842


chr9:120242569
0.966667
57.9022989
0.95833333
0.9


chr6:148509695
0.96657
9.42982456
0.97674419
0.875


chr1:153536157
0.966216
24.047619
0.94594595
1


chr9:120242617
0.966071
55.2380952
0.875
1


chr12:31009603
0.965774
55.2255639
0.9047619
1


chr18:62333487
0.965608
29.8469388
0.97619048
0.88888889


chr8:140270737
0.965157
68.8577586
0.97560976
0.85714286


chr19:3655888
0.965116
39.6011396
0.90697674
1


chr17:82001529
0.964939
31.9123601
0.92682927
1


chr7:102424329
0.964939
86.1904762
0.92682927
0.875


chr2:200087071
0.964744
44.1520468
0.8974359
1


chr16:85287095
0.964474
47.0208333
0.83333333
1


chr11:855972
0.964286
83.7792461
0.925
1


chr11:855981
0.964286
50.6097561
0.925
1


chr9:120242622
0.964286
5.55555556
0.975
0.85714286


chr19:3656250
0.964115
79.3706294
0.90909091
0.94736842


chr20:19836028
0.964063
31.1987705
0.975
0.875


chr1:944699
0.963816
6.10795455
0.97368421
0.875


chr17:2418940
0.963816
83.0143541
0.86842105
1


chr3:185397845
0.963816
77.3504274
0.81578947
1


chr7:44151120
0.963508
80.9090909
0.83333333
0.94117647


chr11:35853892
0.963415
66.3793103
0.87804878
1


chr12:123253744
0.963415
87.8676471
0.90243902
1


chr20:49345788
0.963415
10.8930864
0.90243902
1


chr6:34128234
0.963415
72.2222222
0.97560976
0.875


chr7:750747
0.963415
31.127451
1
0.875


chr2:205764439
0.963141
31.40625
0.8974359
1


chr18:59050139
0.962963
73.030303
0.87037037
0.94117647


chr5:172103442
0.962798
54.8717949
0.88095238
1


chr9:120242544
0.9625
65.1515152
0.875
1


chr1:28869207
0.962165
27.6794035
0.87931034
1


chr16:11997774
0.961794
89.4444444
0.88372093
1


chr8:134499858
0.961749
78.3482143
1
0.88888889


chr17:29158240
0.961672
85.2419355
0.85365854
1


chr1:54356559
0.961538
14.2294713
0.92307692
1


chr6:34545466
0.96131
61.5196078
0.88095238
1


chr8:134941060
0.961111
49.137931
0.825
1


chr10:101780858
0.960938
87.75
0.85
1


chr19:12953855
0.960938
12.3737374
0.9
1


chr3:53702770
0.960714
81.3580247
0.9
1


chr12:56997304
0.960366
60.2955665
0.97560976
0.875


chr6:34128223
0.960366
75
0.97560976
0.875


chr18:77053845
0.960317
87.3015873
0.92857143
0.88888889


chr20:22557408
0.960227
60.2564103
0.90909091
1


chr6:110414306
0.96
65.1515152
0.88
1


chr9:136013178
0.96
76.8421053
0.91428571
1


chr1:230759612
0.959936
47.008547
0.92307692
1


chr6:44261814
0.959936
86.1904762
0.87179487
1


chr6:42963345
0.959472
70.094086
0.91803279
0.88888889


chr9:95738191
0.959375
69.8591549
0.9
1


chr16:85355101
0.95935
78.4615385
0.87804878
1


chr19:2354863
0.959302
81.6666667
0.90697674
1


chr1:53320016
0.959302
20.0910931
0.90697674
1


chr16:70318894
0.958929
89.6057348
0.925
0.85714286


chr16:85696894
0.958333
83.2329317
0.78333333
1


chr17:82001584
0.958333
12.5966944
0.95238095
0.875


chr2:200087032
0.958333
48.8529015
0.8974359
1


chr7:128075308
0.958333
69.6153846
0.92105263
1


chr1:32885121
0.958188
11.9767442
0.97560976
0.85714286


chr21:41665312
0.958188
47.7272727
0.87804878
1


chr7:128881062
0.957955
46.875
0.85454545
1


chr6:169160984
0.957849
54.5694502
0.88372093
1


chr3:196992182
0.957722
63.7934603
0.91803279
0.94736842


chr6:40349319
0.957672
18.7280702
0.95238095
0.88888889


chr7:44151126
0.957639
26.1363636
0.95833333
0.86666667


chr1:54356214
0.957483
38.8560158
0.97619048
0.85714286


chr7:5276684
0.957447
40.6565657
0.95744681
0.88888889


chr19:38253104
0.957418
67.5438596
0.80769231
1


chr1:204921255
0.957317
63.9423077
0.85365854
1


chr1:224184849
0.957317
86.2263185
0.90243902
1


chr11:48025532
0.957317
38.6540354
0.87804878
1


chr5:16538197
0.957317
58.5883313
0.90243902
1


chr1:153536113
0.957207
19.2156863
0.89189189
1


chr1:153536123
0.957207
20
0.86486486
1


chr9:124820965
0.957023
46.4102564
0.8490566
1


chr21:41639350
0.956944
86.1642743
0.8
1


chr9:113901422
0.956897
69.924812
0.89655172
0.94444444


chr1:11965505
0.956731
67.9487179
0.87179487
1


chr6:168638645
0.956446
84.5238095
0.87804878
1


chr17:29582881
0.95625
92.1538462
0.85
1


chr3:71074388
0.95625
97.2222222
0.8
1


chr9:134486435
0.956044
93.0952381
0.8974359
1


chr19:48350605
0.956044
38.1944444
0.97435897
0.85714286


chr19:3656178
0.955997
68.967033
0.86885246
0.94736842


chr11:118901571
0.955966
50.5555556
0.93181818
0.875


chr1:43550383
0.955882
89.4444444
0.94117647
1


chr12:123253763
0.955793
83.8068182
0.87804878
1


chr16:30030208
0.955793
16.1764706
0.85365854
1


chr21:41648785
0.955793
79.1025641
0.80487805
1


chr9:91810447
0.955744
67.8466077
0.79661017
1


chr10:79313956
0.955592
63.0409357
0.97368421
0.875


chr6:169190341
0.955592
51.0683761
0.86842105
1


chr16:85436880
0.955182
16.9047619
0.94117647
0.85714286


chr1:1921165
0.955128
60.7142857
0.92307692
0.875


chr1:205447760
0.955
67.2619048
0.925
1


chr1:153536136
0.954955
8.89328063
0.89189189
1


chr1:153536146
0.954955
24.047619
0.86486486
1


chr11:19730746
0.954688
51.8965517
0.975
0.875


chr3:141093639
0.954688
77.8954802
0.875
1


chr2:159228539
0.954545
83.2167832
0.87755102
1


chr21:17508899
0.954392
68.3333333
0.91891892
0.875


chr11:66866541
0.954268
29.122807
0.92682927
1


chr17:66830069
0.954268
10.1010101
0.85365854
1


chr20:49345770
0.954268
14.7244806
0.87804878
1


chr20:63835571
0.954268
16.4241486
0.87804878
1


chr9:127200650
0.954268
84.9306431
0.85365854
1


chr19:4055918
0.954082
85.3571429
0.9047619
1


chr9:131810494
0.954023
47.6842105
0.84482759
1


chr19:38253123
0.953984
39.5833333
0.96153846
0.85714286


chr1:60903781
0.953832
32.7387802
0.9122807
0.94736842


chr22:20014786
0.953782
70.8712121
0.80357143
1


chr1:25771857
0.953721
49.5967742
0.9137931
0.94736842


chr17:67652635
0.953408
78.8433908
0.95081967
0.89473684


chr9:93166951
0.953333
45.2685422
0.98
0.86666667


chr13:73218843
0.953125
78.6290323
0.825
1


chr7:136045406
0.952744
31.0990338
0.97560976
0.875


chr14:73228468
0.952721
40.9803922
0.88135593
1


chr17:50831246
0.952721
57.1777547
0.88135593
0.94736842


chr7:30171980
0.952641
89.2857143
0.86885246
0.94444444


chr17:67652633
0.952545
84.841954
0.98360656
0.89473684


chr1:28869065
0.952448
45.5882353
0.86440678
1


chr13:113818528
0.952381
75.5744256
0.83333333
1


chr2:200087031
0.952381
50
0.91666667
1


chr2:200087051
0.952381
50
0.91666667
1


chr6:168517547
0.952381
92.476489
0.81632653
1


chr6:35534674
0.952326
18.3333333
0.86046512
1


chr6:35534714
0.952326
27.8846154
0.90697674
1


chr6:148509713
0.952035
14.2992424
0.81395349
1


chr19:3656386
0.951977
80.8551308
0.96610169
0.88888889


chr11:19832444
0.951961
52.7777778
0.95
0.82352941


chr13:112775959
0.951754
85.5147059
0.92105263
1


chr22:19632813
0.951705
68.8194444
0.84090909
1


chr5:760546
0.951705
45.9961998
0.93181818
0.875


chr19:3950318
0.951681
30.3846154
0.88235294
1


chr1:60903756
0.951524
25.6363636
0.92982456
0.94736842


chr7:8070969
0.951302
94.8684211
0.90163934
0.88235294


chr16:70730157
0.951267
71.4912281
0.92982456
0.88888889


chr20:49345761
0.95122
26.8518519
0.90243902
1


chr3:45819148
0.95122
86.1904762
0.85365854
1


chr6:19719834
0.95122
7.35632184
0.97560976
0.875


chr6:34128254
0.95122
62.962963
0.97560976
0.875


chr6:34128257
0.95122
90.2777778
0.90243902
0.875


chr6:168130634
0.95122
75.990566
0.82926829
1


chr1:15723893
0.951128
89.5833333
0.81578947
1


chr16:85287162
0.950998
19.2265481
0.93103448
0.84210526


chr7:1815269
0.95098
27.7777778
0.85294118
1


chr9:93166950
0.950893
39.2592593
0.97619048
0.875


chr16:85287116
0.950877
23.0424528
0.9
0.94736842


chr17:67652568
0.95082
78.0357143
0.93442623
0.88888889


chr12:123253794
0.95068
66.5789474
0.9047619
1


chr16:85287098
0.95
34.3918011
0.85
1


chr18:77077978
0.95
89.6808511
0.8
1


chr19:46714207
0.95
6.11111111
0.82857143
1


chr3:53702765
0.95
48.0769231
0.975
0.85714286


chr7:3998211
0.95
52.2727273
0.85
1


chr9:92729620
0.95
30.625
0.8
1


chr16:85436709
0.949957
33.5486405
0.8852459
0.89473684


chr11:66866538
0.949695
67.7083333
0.82926829
1


chr22:44248796
0.949695
80.0986842
0.97560976
0.875


chr6:34545471
0.949405
45.8333333
0.9047619
1


chr7:102424320
0.949187
54.1666667
0.97560976
0.83333333


chr17:602149
0.949153
78.1889764
0.96610169
0.8125


chr20:22557482
0.949128
82.3076923
0.8372093
1


chr6:3444679
0.94898
73.6231884
0.9047619
1


chr17:57707866
0.94883
57.7777778
0.89473684
0.88888889


chr16:11654442
0.948803
54.5454545
0.85106383
0.9375


chr19:3655812
0.948765
30.3846154
0.98148148
0.86666667


chr13:109334658
0.948718
22.1774194
0.87179487
1


chr1:43550373
0.948529
88.75
0.91176471
1


chr2:73080399
0.948413
89.8989899
0.8
1


chr9:131810462
0.948343
75.6188119
0.9122807
0.94444444


chr1:227920141
0.94832
40.6593407
1
0.77777778


chr1:153536121
0.948198
10.8333333
0.89189189
1


chr20:50035301
0.948171
88.7067395
0.80487805
1


chr20:38700627
0.948171
3.01036683
0.95121951
0.875


chr21:41553133
0.948171
70.2256245
0.85365854
1


chr21:41648778
0.948171
66.1202186
0.82926829
1


chr6:168130595
0.948171
76.3888889
0.82926829
1


chr6:168539582
0.948122
64.4144144
0.95348837
0.92307692


chr7:5276649
0.947991
39.514652
0.78723404
1


chr21:40144935
0.947917
88.3484163
0.88095238
1


chr19:3656261
0.947847
62.8289474
0.89090909
0.94736842


chr3:139718818
0.947727
44.9494949
0.88636364
0.93333333


chr1:10625828
0.947674
89.4444444
0.81395349
1


chr3:185397835
0.947368
80.1282051
0.78947368
1


chr7:110084403
0.947368
77.3504274
0.81578947
1


chr5:176843791
0.947154
46.6403162
0.90243902
0.88888889


chr6:40349351
0.94709
21.5384615
0.88095238
1


chr9:113901566
0.94697
78.8781275
0.89090909
0.88888889


chr21:41179996
0.946875
83.1300813
0.825
1


chr4:528986
0.94666
71.657754
0.88135593
0.88235294


chr12:48675786
0.946646
70.0892857
0.95121951
0.875


chr19:13634667
0.946646
89.2720307
0.82926829
1


chr6:168130574
0.946646
78.6764706
0.87804878
1


chr19:3656190
0.946506
78.9181287
0.86885246
0.94736842


chr1:202168439
0.946461
55.9382992
0.77586207
1


chr12:124428932
0.946445
26.3988095
0.89473684
0.89473684


chr6:34545461
0.946429
34.3137255
0.85714286
1


chr7:3998240
0.946429
16.5178571
0.875
1


chr3:127304410
0.945946
5.01253133
0.78378378
1


chr16:89847327
0.945833
82.9326923
0.925
0.83333333


chr1:226638169
0.945685
65.8181818
0.9047619
0.875


chr1:181128695
0.945626
28.230042
0.85106383
1


chr1:54356181
0.945578
79.6697626
0.78571429
1


chr12:123253764
0.945578
85.4138133
0.85714286
1


chr11:64056580
0.945513
86.0576923
0.88461538
0.91666667


chr3:47236186
0.945437
65.4761905
0.85714286
0.94444444


chr16:85436855
0.945378
17.4710425
0.90196078
0.85714286


chr11:888597
0.945313
80.625
0.90384615
0.9375


chr19:4010290
0.945313
15.6174334
0.9
1


chr1:53320091
0.945122
61.1642743
1
0.75


chr1:205257276
0.945122
61.5455665
0.7804878
1


chr19:4010298
0.945122
19.1967325
0.87804878
1


chr21:41648770
0.945122
87.7622378
0.92682927
1


chr7:122306890
0.94494
44.3344892
0.9047619
1


chr20:11271554
0.944907
27.2030651
0.86666667
0.94444444


chr4:7911302
0.944643
44.8809524
0.95
0.85714286


chr1:28869195
0.944444
10.0335149
0.93103448
0.94444444


chr16:2455154
0.944444
89.2857143
0.86206897
1


chr5:176843804
0.944444
59.1666667
0.7804878
1


chr7:5276677
0.944444
57.7777778
0.87234043
0.88888889


chr1:220653196
0.944251
54.2063492
0.97560976
0.85714286


chr11:888641
0.944111
72.2506394
0.92307692
0.9375


chr19:38253076
0.94391
44.8091382
0.90384615
0.91666667


chr4:1858204
0.94391
70.0320513
0.97435897
0.75


chr8:38495138
0.94391
32.2516026
0.94230769
0.88888889


chr3:141093636
0.94375
78.4782609
0.85
1


chr1:31627824
0.943598
43.6507937
0.85365854
1


chr12:48675768
0.943598
86.6071429
0.95121951
0.875


chr2:190034714
0.943598
92.1538462
0.82926829
1


chr6:168638690
0.943598
65.1515152
0.87804878
1


chr19:3656351
0.943503
33.3116883
0.96610169
0.83333333


chr12:131864061
0.943434
48.6842105
0.83636364
1


chr9:89591607
0.943414
58.0662651
0.91836735
0.90909091


chr17:74823356
0.943277
78.5361842
0.94117647
0.92857143


chr16:85287017
0.94303
27.9220779
0.98181818
0.8


chr16:88887476
0.943027
28.7466844
0.95918367
0.91666667


chr2:96174325
0.942982
33.5164835
0.89473684
1


chr6:3444622
0.942935
52.2727273
0.91304348
0.9375


chr1:5917479
0.942929
62.2580645
0.90909091
0.88888889


chr1:1240684
0.942857
29.8148148
0.88571429
1


chr12:130483799
0.942857
77.5
0.95
0.85714286


chr13:110123705
0.942857
30.4377283
0.875
1


chr6:168496991
0.942857
65.6862745
0.875
1


chr8:53733503
0.942593
34.7486704
0.91666667
0.88888889


chr7:105689129
0.942544
71.0606061
0.95
0.84210526


chr2:113974997
0.942455
16.025641
0.97826087
0.82352941


chr12:591924
0.942308
8.22072072
0.92307692
0.875


chr15:65333873
0.942308
54.1666667
0.97435897
0.875


chr3:194305584
0.942105
81.5636201
0.9
0.89473684


chr19:4059381
0.942105
57.0082285
0.93333333
0.89473684


chr18:59049874
0.942073
6.27185315
0.85365854
1


chr1:224184822
0.942073
86.9747899
0.82926829
1


chr11:76175216
0.942073
82.9090909
0.95121951
0.875


chr6:168130594
0.942073
81.3043478
0.87804878
1


chr19:3655954
0.941964
19.4444444
0.85416667
1


chr19:34999970
0.941667
9.33908046
0.9
1


chr6:26614205
0.941667
26.1363636
0.9
1


chr10:78139388
0.941558
16.0106383
0.96969697
0.78571429


chr11:122984321
0.941463
0.57142857
0.82926829
1


chr19:3656172
0.941329
52.8532525
0.90163934
0.89473684


chr1:43550344
0.941176
35
0.88235294
1


chr12:129694731
0.941176
37.5
0.88235294
1


chr19:3655828
0.941176
75.5555556
0.90909091
0.94117647


chr7:151045548
0.941176
17.9487179
1
0.83333333


chr12:130483815
0.941071
89.7368421
0.8
1


chr5:78519838
0.941057
83.7719298
0.7804878
1


chr11:888359
0.940897
55.1101073
0.95081967
0.84210526


chr1:205032318
0.940776
34.4344609
0.9245283
0.94444444


chr9:120242579
0.940625
65.1515152
0.89583333
0.9


chr1:16486605
0.940549
87.5
0.90243902
0.875


chr1:20348597
0.940549
56.8206522
0.90243902
1


chr2:43203382
0.940549
81.6666667
0.95121951
0.875


chr6:168130603
0.940549
84.0705128
0.90243902
0.875


chr17:3695871
0.940541
16.25
0.89189189
1


chr11:19714522
0.940476
0.75757576
0.88095238
1


chr16:85439179
0.940476
81.5340909
0.94117647
0.92857143


chr7:122306891
0.940476
45.7391304
0.88095238
1


chr9:130233164
0.940407
69.047619
0.88372093
0.875


chr2:47020392
0.940404
81.0790274
0.83636364
0.94444444


chr19:3655938
0.940199
28.4271284
0.79069767
1


chr8:58989422
0.94
94.6540881
0.825
1


chr17:80001489
0.939815
85.9782609
0.91666667
0.83333333


chr2:5530198
0.939815
35.5567227
0.85
1


chr19:3656393
0.939736
91.2518854
0.89830508
0.94444444


chr7:1815299
0.939542
22.875817
0.85294118
1


chr21:43860194
0.939353
48.7903226
0.94339623
0.85714286


chr6:168355227
0.939333
79.4736842
0.88
0.93333333


chr1:20348596
0.939286
64.9122807
0.875
1


chr7:5478011
0.93913
64.4137931
0.82608696
1


chr2:200087040
0.939103
45.0067476
0.87179487
1


chr19:48371166
0.939084
86.1620235
0.92982456
0.88888889


chr16:22288921
0.939063
80.6134529
0.75
1


chr19:12953833
0.939063
3.44064386
0.9
1


chr11:888360
0.939024
78.4090909
0.92682927
1


chr5:16538196
0.939024
71.8939394
0.7804878
1


chr1:9251757
0.939024
39.5743146
0.90243902
1


chr11:924646
0.939024
50.4716981
0.95121951
0.875


chr12:131864094
0.939024
64.9122807
0.82926829
1


chr2:25701937
0.939024
67.4107143
0.7804878
1


chr6:168538915
0.939024
57.7380952
0.85365854
1


chr9:127636823
0.939024
92.010582
0.75609756
1


chr1:22809032
0.938953
42.2619048
0.86046512
1


chr17:29065994
0.938802
85.1449275
0.83333333
1


chr6:168517537
0.938776
94.7169059
0.7755102
1


chr4:6308178
0.938641
36.3697706
0.89655172
0.94117647


chr1:61198659
0.938519
82.9710145
0.93333333
0.93333333


chr20:11271453
0.938448
69.2420682
0.79661017
0.94736842


chr7:44151141
0.938194
54.4155844
0.8125
0.93333333


chr19:18745096
0.938158
57.6973684
0.9
0.84210526


chr7:30172111
0.937963
38.9285714
0.83333333
0.94444444


chr6:34433316
0.937937
81.3852814
0.79545455
1


chr12:119869919
0.9375
76.3888889
0.82926829
1


chr13:110123752
0.9375
36.2899178
0.9
1


chr17:29582888
0.9375
95.7935711
0.825
1


chr18:36468445
0.9375
42.0168067
0.90243902
0.875


chr19:4010297
0.9375
22.9813665
0.87804878
1


chr19:39307494
0.9375
26.6590389
0.875
0.9


chr20:63835620
0.9375
16.4224664
0.80487805
1


chr21:41375919
0.9375
60.6060606
0.95121951
0.875


chr5:6859175
0.9375
43.4210526
0.97560976
0.875


chr6:37537680
0.9375
79.5726496
0.75609756
1


chr7:100122236
0.9375
15.8852678
0.82926829
1


chr9:93959419
0.9375
69.047619
0.91428571
0.875


chr9:91810580
0.937382
77.8846154
0.89830508
0.94444444


chr17:73726103
0.937281
54.4117647
0.91666667
0.94736842


chr1:226589216
0.937276
81.6666667
0.74193548
1


chr9:23452269
0.937255
52.1200144
0.86666667
0.88235294


chr6:42963307
0.937158
61.8055556
0.91803279
0.88888889


chr8:140321186
0.936911
91.5341812
0.86440678
0.94444444


chr16:85287074
0.936842
34.5788043
0.8
1
















TABLE 29







DNA methylation sites associated with SCLC-P











MethylationSite
AUC
threshold
specificity
sensitivity














chr1:11032833
1
27.8846154
1
1


chr1:15207848
1
8.33333333
1
1


chr1:15945017
1
86.0576923
1
1


chr1:17026179
1
81.6666667
1
1


chr1:25741499
1
76.6666667
1
1


chr1:27551002
1
68.4848485
1
1


chr1:32327585
1
70.8333333
1
1


chr1:42682988
1
3.03571429
1
1


chr1:52365896
1
10.1010101
1
1


chr1:56552275
1
53.9393939
1
1


chr1:116407596
1
79.3706294
1
1


chr1:147829076
1
96.7204797
1
1


chr1:156538486
1
80.9615385
1
1


chr1:156750879
1
5.60606061
1
1


chr1:164576909
1
65.6160823
1
1


chr1:197915932
1
61.3636364
1
1


chr1:204289083
1
5
1
1


chr1:204571233
1
66.6666667
1
1


chr1:212618744
1
28.5714286
1
1


chr1:212618752
1
15.7142857
1
1


chr1:212638013
1
42.032967
1
1


chr1:231162869
1
21.031746
1
1


chr1:231162872
1
20.3216374
1
1


chr1:231162880
1
29.9707602
1
1


chr10:14365352
1
18.8995215
1
1


chr10:55631088
1
95
1
1


chr10:55631097
1
50.4444444
1
1


chr10:97713353
1
54.1666667
1
1


chr10:97713362
1
80.5555556
1
1


chr10:123017613
1
11.7816092
1
1


chr11:63997490
1
77.0833333
1
1


chr11:65536690
1
78.4615385
1
1


chr11:75410397
1
71.3636364
1
1


chr11:77750252
1
27.1428571
1
1


chr11:126313324
1
41.375969
1
1


chr12:433809
1
61.525974
1
1


chr12:7291128
1
53.6375661
1
1


chr12:57128650
1
10.2678571
1
1


chr12:67389978
1
65.1515152
1
1


chr12:75861004
1
84.6590909
1
1


chr12:81759542
1
73.8888889
1
1


chr12:85489437
1
66.6666667
1
1


chr12:101309330
1
70.0680272
1
1


chr12:103993054
1
78.3625731
1
1


chr12:104599362
1
86.1111111
1
1


chr12:104599370
1
84.1666667
1
1


chr12:105977083
1
47.7777778
1
1


chr12:110245057
1
69.3549601
1
1


chr12:110245058
1
70.7064793
1
1


chr12:110245093
1
84.8154802
1
1


chr12:111841988
1
6.79824561
1
1


chr12:120456258
1
50
1
1


chr12:122032753
1
33.8135593
1
1


chr12:122032775
1
32.3584906
1
1


chr12:124497504
1
20.7142857
1
1


chr12:124524949
1
53.2467532
1
1


chr12:124631301
1
76.7857143
1
1


chr13:20345144
1
98.828125
1
1


chr14:89701670
1
6.9047619
1
1


chr14:105392906
1
80.3571429
1
1


chr14:105392911
1
77.0833333
1
1


chr15:43746172
1
6.54761905
1
1


chr15:58701617
1
15.3947368
1
1


chr15:74789232
1
25.3205128
1
1


chr15:74789276
1
11.025641
1
1


chr15:74789281
1
12.0289855
1
1


chr16:234790
1
6.06617647
1
1


chr16:234826
1
6.06617647
1
1


chr16:648840
1
75
1
1


chr16:1498961
1
32.9062406
1
1


chr16:1746192
1
84.9906191
1
1


chr16:2075993
1
5.08474576
1
1


chr16:2964040
1
49.1666667
1
1


chr16:4767447
1
8.11688312
1
1


chr16:8621572
1
11.25
1
1


chr16:28193303
1
3.57142857
1
1


chr16:28863649
1
5
1
1


chr16:29906931
1
83.7662338
1
1


chr16:30125736
1
67.1328671
1
1


chr16:30973692
1
66.6666667
1
1


chr16:66696829
1
6.06617647
1
1


chr16:68341637
1
46.4285714
1
1


chr16:85611879
1
9.72222222
1
1


chr17:21665928
1
22.8947368
1
1


chr17:29576080
1
55.4179567
1
1


chr17:34252590
1
92.8571429
1
1


chr17:43187274
1
74.2857143
1
1


chr17:48932449
1
77.5
1
1


chr17:49816143
1
3.84615385
1
1


chr17:63383824
1
38.4615385
1
1


chr17:63383830
1
36.8055556
1
1


chr17:63739476
1
52.0833333
1
1


chr17:64661931
1
12.6984127
1
1


chr17:68205724
1
7.63157895
1
1


chr17:72165644
1
7.69230769
1
1


chr17:76420086
1
4.76190476
1
1


chr17:77439476
1
6.25
1
1


chr17:77439513
1
9.375
1
1


chr17:81248481
1
58.7912088
1
1


chr17:81248517
1
80.4615385
1
1


chr18:5543758
1
46.8137255
1
1


chr18:5543760
1
47.9166667
1
1


chr18:5543767
1
39.7058824
1
1


chr18:5543774
1
64.5833333
1
1


chr18:14907472
1
85.4545455
1
1


chr18:28175723
1
51.3888889
1
1


chr18:28175730
1
62.5
1
1


chr18:28175734
1
65.4121864
1
1


chr18:28175743
1
59.8566308
1
1


chr18:57574427
1
67.9251701
1
1


chr19:807444
1
20.3007519
1
1


chr19:811705
1
62.7403846
1
1


chr19:991153
1
57.7586207
1
1


chr19:991161
1
49.1666667
1
1


chr19:1633524
1
22.5524476
1
1


chr19:1993008
1
13.2575758
1
1


chr19:2115209
1
78.4090909
1
1


chr19:5618219
1
79.2717087
1
1


chr19:11483864
1
5
1
1


chr19:11483872
1
5
1
1


chr19:11483877
1
5
1
1


chr19:11483882
1
15
1
1


chr19:11483887
1
16.3461538
1
1


chr19:11483902
1
8.33333333
1
1


chr19:11483907
1
10
1
1


chr19:11483912
1
5.55555556
1
1


chr19:14206288
1
25.3846154
1
1


chr19:14559510
1
51.754386
1
1


chr19:16628375
1
12.5
1
1


chr19:17209718
1
31.9642857
1
1


chr19:17209725
1
29.1071429
1
1


chr19:17209733
1
12.8571429
1
1


chr19:17209752
1
18.5714286
1
1


chr19:18778224
1
1.13636364
1
1


chr19:35721194
1
34.1666667
1
1


chr19:35944911
1
74.9016522
1
1


chr19:38907710
1
60.3896104
1
1


chr19:42211188
1
81.6666667
1
1


chr19:45712682
1
45.2380952
1
1


chr19:49464557
1
76.9736842
1
1


chr19:49881697
1
65.4605263
1
1


chr19:55284281
1
5.57275542
1
1


chr19:55615832
1
81.5340909
1
1


chr2:9003857
1
6.79824561
1
1


chr2:61166980
1
59.1666667
1
1


chr2:89848744
1
50.5050505
1
1


chr2:190440760
1
28.5714286
1
1


chr2:200981406
1
11.4074074
1
1


chr2:202250239
1
21.3315217
1
1


chr2:209772183
1
19.7115385
1
1


chr2:224690031
1
48.0392157
1
1


chr20:1185694
1
6.69642857
1
1


chr20:62122215
1
3.61290323
1
1


chr20:62309811
1
81.9444444
1
1


chr20:62328882
1
87.593985
1
1


chr20:63667368
1
76.3888889
1
1


chr21:5137123
1
83.7719298
1
1


chr21:25735328
1
13.3333333
1
1


chr21:41879374
1
7.41758242
1
1


chr21:43882191
1
30.5555556
1
1


chr21:45277832
1
65.2941176
1
1


chr22:31098838
1
64.375
1
1


chr22:33058579
1
77.5
1
1


chr22:40026246
1
73.8636364
1
1


chr22:49884754
1
69.7777778
1
1


chr3:13366052
1
73.3276158
1
1


chr3:112523580
1
9.52380952
1
1


chr3:112523614
1
29.1666667
1
1


chr3:128428346
1
10.4761905
1
1


chr3:138798882
1
86.8534483
1
1


chr3:150408978
1
5.26675787
1
1


chr3:157067444
1
2.60869565
1
1


chr3:165348114
1
18.3333333
1
1


chr3:165348116
1
18.3333333
1
1


chr3:186783828
1
11.9505495
1
1


chr3:197297920
1
5.04807692
1
1


chr4:1229607
1
83.3333333
1
1


chr4:4438102
1
57.0454545
1
1


chr5:3750940
1
99.6296296
1
1


chr5:6615113
1
79.5138889
1
1


chr5:16179849
1
80
1
1


chr5:16179857
1
55.7142857
1
1


chr5:16179865
1
62.8571429
1
1


chr5:16179878
1
80
1
1


chr5:16179881
1
85
1
1


chr5:16179883
1
95
1
1


chr5:16180008
1
84.6153846
1
1


chr5:178204129
1
30.6100218
1
1


chr5:178204131
1
20.0980392
1
1


chr6:3577167
1
21.8864469
1
1


chr6:27279630
1
95.8333333
1
1


chr6:73310426
1
77.8571429
1
1


chr6:73310429
1
80
1
1


chr6:73310454
1
54.4642857
1
1


chr6:73310463
1
83.3333333
1
1


chr6:125791186
1
10.7142857
1
1


chr6:136290429
1
10.4761905
1
1


chr7:996193
1
14.6428571
1
1


chr7:1551166
1
87.4509804
1
1


chr7:1849861
1
59.0277778
1
1


chr7:1854236
1
14.8351648
1
1


chr7:4730195
1
27.5641026
1
1


chr7:5070131
1
79.1666667
1
1


chr7:6333296
1
43.1818182
1
1


chr7:15848453
1
22.2222222
1
1


chr7:26247657
1
31.3131313
1
1


chr7:29643153
1
78.8888889
1
1


chr7:30043812
1
84.5238095
1
1


chr7:43877706
1
80.1948052
1
1


chr7:44146254
1
10.7142857
1
1


chr7:44748739
1
8.88888889
1
1


chr7:149022546
1
70.8333333
1
1


chr8:31640044
1
15.2631579
1
1


chr8:31640053
1
16.2962963
1
1


chr8:31640067
1
17.3219373
1
1


chr8:42842942
1
8.05555556
1
1


chr8:80578027
1
9.54545455
1
1


chr9:107245787
1
71.25
1
1


chr9:120913537
1
62.5
1
1


chr9:126408197
1
86.5100976
1
1


chr9:131584010
1
75.877193
1
1


chr9:136197462
1
3.125
1
1


chr9:136451036
1
63.8586957
1
1


chr9:136451222
1
64.2857143
1
1


chr9:136451519
1
71.6008772
1
1


chr9:137013461
1
18.5185185
1
1


chr9:137013470
1
28.5714286
1
1


chr9:137013473
1
60.7142857
1
1


chr9:137013486
1
43.3982684
1
1


chr9:137278360
1
43.75
1
1


chr9:137278384
1
68.3333333
1
1


chr9:137278402
1
43.75
1
1


chr9:137278488
1
13.2716049
1
1


chrX:150899022
1
65.7738095
1
1


chr6:34553001
0.996711
29.4047619
0.98684211
1


chr12:118980854
0.996667
11.7592593
0.98666667
1


chr19:811773
0.996667
60.9090909
0.98666667
1


chr2:130345606
0.996622
79.9342105
0.98648649
1


chr2:202250236
0.996377
17.5
0.98550725
1


chr7:1005784
0.996377
87.3015873
0.98550725
1


chr19:7934275
0.995763
50.6756757
0.98305085
1


chr14:34024477
0.995726
38.0392157
0.97435897
1


chr7:107390004
0.995614
69.8198198
0.98245614
1


chr1:25216043
0.99537
41.6666667
0.98148148
1


chr15:85610808
0.995169
82.5098039
0.98550725
1


chr19:5668214
0.995
31.832265
0.98
1


chr7:5297184
0.995
35.6504932
0.98
1


chr1:241356405
0.994898
12.406015
0.97959184
1


chr10:102714534
0.994898
3.22439567
0.97959184
1


chr8:31640064
0.994872
16.1403509
0.98461538
1


chr12:120967099
0.994792
58.3333333
0.984375
1


chr19:1393965
0.994792
61.6082603
0.97916667
1


chr15:25438570
0.994643
4.375
0.97142857
1


chr15:74789270
0.994565
27.8861789
0.97826087
1


chr7:5297124
0.994565
40.4304029
0.97826087
1


chr8:123443315
0.994565
49.2068619
0.97826087
1


chr1:180269892
0.994444
44.3069887
0.97777778
1


chr19:1456332
0.994444
19.1919192
0.97777778
1


chr16:73028748
0.994186
45.0657895
0.97674419
1


chr2:75056446
0.994186
35.485348
0.97674419
1


chr19:18543346
0.994152
0.64750789
0.98245614
1


chr2:75056435
0.994048
36.6649755
0.97619048
1


chr2:75056445
0.994048
45.625
0.97619048
1


chr16:29876586
0.99375
83.7719298
0.975
1


chr6:43771035
0.99359
4.46428571
0.97435897
1


chr12:124344199
0.993421
68.6065574
0.98684211
1


chr8:139649190
0.993333
65.6862745
0.98666667
1


chr2:230068915
0.993243
93.75
0.98648649
1


chr1:6461087
0.993151
72.1661055
0.97260274
1


chr1:234661304
0.993151
68.3333333
0.98630137
1


chr12:7824990
0.993151
56.5860215
0.98630137
1


chr16:71931876
0.993151
80.2777778
0.97260274
1


chr21:36736273
0.993151
98.3870968
0.98630137
1


chr3:183636771
0.993151
8.71212121
0.98630137
1


chr5:143405413
0.993151
10.1010101
0.98630137
1


chr10:69402478
0.993056
92.1212121
0.97222222
1


chr14:104887313
0.993056
72.3809524
0.98611111
1


chr16:1315523
0.993056
85.7843137
0.97222222
1


chr7:2295681
0.993056
79.1666667
0.97222222
1


chr1:214108494
0.992857
55.7692308
0.98571429
1


chr1:236064214
0.992857
96.4285714
0.98571429
1


chr2:44168465
0.992857
10.960961
0.98571429
1


chr2:114662163
0.992857
96.1538462
0.98571429
1


chr3:107999730
0.992857
55.7692308
0.98571429
1


chr6:3577155
0.992857
24.9762583
0.98571429
1


chr6:3577177
0.992857
25.3407984
0.98571429
1


chr7:57818168
0.992857
54.2053446
0.97142857
1


chr1:41324219
0.992754
52.1008403
0.98550725
1


chr1:213051051
0.992754
78.8888889
0.98550725
1


chr11:4521815
0.992754
96.875
0.98550725
1


chr12:43552603
0.992754
96.6666667
0.98550725
1


chr17:35488134
0.992754
97.7272727
0.98550725
1


chr3:14401986
0.992754
1.92307692
0.98550725
1


chr6:13450944
0.992754
82.0855615
0.98550725
1


chr9:101738883
0.992754
53.015873
0.98550725
1


chr1:167221470
0.992647
3.125
0.97058824
1


chr16:88880826
0.992647
2.63157895
0.98529412
1


chr19:3652127
0.992647
83.974359
0.98529412
1


chr20:17396399
0.992647
1.5625
0.98529412
1


chr12:104599364
0.992537
84.8765432
0.98507463
1


chr16:87827109
0.992537
4.54545455
0.98507463
1


chr19:17873403
0.992537
0.76923077
0.98507463
1


chr19:17873409
0.992537
19.4444444
0.98507463
1


chr19:17873411
0.992537
8.33333333
0.98507463
1


chr6:63656136
0.992537
75.2525253
0.98507463
1


chr12:45216305
0.992424
5.45905707
0.98484848
1


chr12:57837371
0.992424
77.3504274
0.98484848
1


chr16:21557088
0.992424
95.2380952
0.98484848
1


chr17:34331252
0.992424
95
0.98484848
1


chr21:39054428
0.992424
20.8333333
0.98484848
1


chr7:3910633
0.992424
2.94117647
0.98484848
1


chr16:3655081
0.992308
4.28571429
0.98461538
1


chr18:12324746
0.992308
82.3076923
0.98461538
1


chr9:76701152
0.992308
51.9230769
0.98461538
1


chr19:1648427
0.992248
66.1490683
0.97674419
1


chr20:47468584
0.992188
8.33333333
0.984375
1


chr3:96841981
0.992188
71.875
0.984375
1


chr1:239386481
0.992063
41.0526316
0.98412698
1


chr19:3088153
0.992063
31.541769
0.98412698
1


chr20:17396185
0.992063
14.7058824
0.98412698
1


chr6:27557116
0.992063
98.8372093
0.98412698
1


chr6:55680614
0.992063
95
0.98412698
1


chr7:5297111
0.992063
0.69444444
0.98412698
1


chr19:58440360
0.991935
96.1538462
0.98387097
1


chr7:151111578
0.991935
5.88235294
0.98387097
1


chr8:139649329
0.991935
22.5
0.98387097
1


chr19:28520192
0.991803
96.875
0.98360656
1


chr6:34778112
0.991803
80.5555556
0.98360656
1


chr9:131112163
0.991803
64.7163121
0.98360656
1


chr7:102201787
0.991667
92.7291886
0.96
1


chr8:42153025
0.991667
12.1428571
0.98333333
1


chr8:42622755
0.991667
5
0.98333333
1


chr1:154174789
0.991525
71.7948718
0.98305085
1


chr17:49816136
0.991525
2.5
0.98305085
1


chr19:7934266
0.991525
80.625
0.98305085
1


chr19:13207507
0.991525
83.7116423
0.96610169
1


chr2:17317571
0.991525
98.3870968
0.98305085
1


chr5:3754702
0.991525
80.5555556
0.98305085
1


chr6:24626028
0.991525
8.68486352
0.98305085
1


chr6:44653805
0.991525
58.4848485
0.98305085
1


chr2:173307231
0.991477
74.4166667
0.97727273
1


chr6:22509101
0.991379
3.84615385
0.98275862
1


chr8:107889762
0.991379
4.16666667
0.98275862
1


chr5:128879466
0.991197
88.3333333
0.98591549
1


chr19:3094373
0.991111
3.44466537
0.98666667
1


chr17:72235698
0.991071
4.54545455
0.98214286
1


chr21:34510358
0.991071
7.14285714
0.98214286
1


chr9:137013468
0.990909
20.3007519
0.98181818
1


chr9:137013480
0.990909
36.5079365
0.98181818
1


chr1:220001751
0.990868
27.8361345
0.98630137
1


chr5:308909
0.990868
76.7857143
0.97260274
1


chr1:155544582
0.990741
79.4736842
0.98148148
1


chr1:204089544
0.990741
58.5714286
0.97222222
1


chr11:107970310
0.990741
49.95671
0.97222222
1


chr12:95066688
0.990741
34.1346154
0.98148148
1


chr19:16553992
0.990741
70.5802969
0.97222222
1


chr5:16179995
0.990741
85.2941176
0.98148148
1


chr5:16180003
0.990741
90.2777778
0.98148148
1


chr5:25900907
0.990741
3.03030303
0.98148148
1


chr8:35235230
0.990741
96.4285714
0.98148148
1


chr16:28617820
0.990672
31.712963
0.98507463
1


chr17:76419894
0.99061
18.8461538
0.98591549
1


chr19:48194427
0.99061
20.0909091
0.98591549
1


chr7:14695759
0.99061
33.0602637
0.97183099
1


chr1:6470978
0.990566
63.1877023
0.98113208
1


chr1:23636028
0.990566
73.2142857
0.98113208
1


chr20:350196
0.990476
75.9090909
0.97142857
1


chr1:31193833
0.990385
44.1558442
0.98076923
1


chr8:126862783
0.990385
3.84615385
0.98076923
1


chr11:78046094
0.990196
24.4047619
0.97058824
1


chr12:132528585
0.990196
52.2727273
0.96078431
1


chr18:79375872
0.990196
77.3182957
0.97058824
1


chr19:652099
0.990196
78.8847118
0.96078431
1


chr21:9873175
0.990196
47.3214286
0.98039216
1


chr7:57821358
0.990196
68.0555556
0.98529412
1


chr7:101967581
0.990196
66.0714286
0.98039216
1


chr8:144107705
0.990196
26.3931889
0.98529412
1


chr12:62602516
0.99005
6.11111111
0.97014925
1


chr1:6460819
0.99
33.3854286
0.96
1


chr1:244198034
0.99
41.6373239
0.96
1


chr19:5704451
0.99
78.5691971
0.96
1


chr9:137278356
0.99
21.6715332
0.98
1


chr10:76887333
0.989865
65.3370787
0.95945946
1


chr19:1433766
0.989865
72.0779221
0.95945946
1


chr19:13830675
0.989865
77.6344086
0.98648649
1


chr20:37985816
0.989865
61.25
0.95945946
1


chr1:15945048
0.989796
85.1648352
0.97959184
1


chr14:23078131
0.989796
73.8636364
0.97959184
1


chr9:133459357
0.989796
11.6883117
0.95918367
1


chr8:31640070
0.989744
19.0046296
0.98461538
1


chr12:62799867
0.989726
41.3483931
0.98630137
1


chr5:32446706
0.989726
36.0988896
0.98630137
1


chr12:120967103
0.989583
70.2380952
0.96875
1


chr5:128879583
0.989437
44.820296
0.95774648
1


chr15:69087040
0.989418
34.5771144
0.96825397
1


chr20:347269
0.989418
6.69642857
0.98412698
1


chr9:132325224
0.989362
92.5824176
0.95744681
1


chr16:78195948
0.989362
7.14285714
0.9787234
1


chr19:28824412
0.989362
97.3684211
0.9787234
1


chr19:44753544
0.989362
97.0588235
0.9787234
1


chr22:11288465
0.989362
63.0681818
0.9787234
1


chr17:72123931
0.989286
68.1885125
0.95714286
1


chr17:72124220
0.989286
12.3161765
0.98571429
1


chr17:72124238
0.989286
17.7871148
0.98571429
1


chr2:36973823
0.98913
79.5138889
0.97826087
1


chr5:16179886
0.98913
75
0.97826087
1


chr20:44560834
0.988971
19.6428571
0.97058824
1


chr12:50057840
0.988889
3.82414353
0.97777778
1


chr19:1456317
0.988889
16.6666667
0.97777778
1


chr7:1421100
0.988889
2.94117647
0.97777778
1


chr8:123443370
0.988889
46.6494845
0.95555556
1


chr17:82626176
0.988806
86.9334719
0.95522388
1


chr18:63283742
0.988701
59.1269841
0.96610169
1


chr11:65650576
0.988636
88.3965517
0.95454545
1


chr12:31591065
0.988636
11.8055556
0.97727273
1


chr16:73028716
0.988636
76.7857143
0.95454545
1


chr6:106135145
0.988636
45.6547619
0.96969697
1


chr1:230399219
0.988462
21.2053571
0.98461538
1


chr17:80599748
0.988462
12.8264209
0.98461538
1


chr3:136614019
0.988462
87.8571429
0.96923077
1


chr9:93826472
0.988462
44.2307692
0.98461538
1


chr19:812407
0.988372
70.8333333
0.97674419
1


chr6:135771171
0.988372
92.0454545
0.97674419
1


chr9:137278500
0.988304
45.2008929
0.98245614
1


chr16:3987194
0.988281
83.5034014
0.96875
1


chr17:49810078
0.988281
28.8797062
0.984375
1


chr2:164717792
0.988095
86.6071429
0.97142857
1


chr22:40600900
0.988095
84.2751843
0.97619048
1


chr3:123976907
0.988095
56.4393939
0.97619048
1


chr3:123976934
0.988095
81.953867
0.97619048
1


chr2:89244905
0.988014
91
0.98630137
1


chr19:5668194
0.987981
28.709893
0.96153846
1


chr11:78046073
0.987923
20.8333333
0.95652174
1


chr9:127507984
0.987923
56.8181818
0.95652174
1


chr9:120877473
0.987805
7.48663102
0.97560976
1


chr1:159210159
0.987705
90.2380952
0.98360656
1


chr6:44441882
0.987705
14.1666667
0.98360656
1


chr8:101950035
0.987705
89.9038462
0.98360656
1


chr1:11331701
0.9875
51.4705882
0.96666667
1


chr19:1992998
0.9875
26.1363636
0.975
1


chr19:1993003
0.9875
23.3333333
0.975
1


chr9:128704978
0.9875
67.816092
0.975
1


chr9:124453638
0.987421
2.95745921
0.98113208
1


chr19:1468243
0.987288
31.6666667
0.94915254
1


chr16:2429260
0.987179
5.20833333
0.97435897
1


chr20:62309824
0.987179
75.7352941
0.97435897
1


chr7:44146237
0.987179
1.72413793
0.97435897
1


chr8:31640050
0.987179
14.1750842
0.98461538
1


chr9:94914976
0.987179
62.2222222
0.98461538
1


chr12:37419025
0.987069
83.8888889
0.98275862
1


chr12:45776142
0.986979
22.3296888
0.984375
1


chr17:42670166
0.986842
78.125
0.97368421
1


chr19:1633551
0.986842
25.625
0.97368421
1


chr9:137281710
0.986842
70
0.97368421
1


chr1:214281447
0.986842
5.15873016
0.98684211
1


chr6:34553086
0.986842
68.7062937
0.96052632
1


chr1:167918494
0.986742
64.1121495
0.98484848
1


chr17:72123590
0.986667
2.08333333
0.97333333
1


chr19:45067160
0.986667
84.8287238
0.98666667
1


chr6:157300486
0.986667
78.9784946
0.97333333
1


chr7:1734991
0.986667
2.17391304
0.97333333
1


chr7:1734996
0.986667
2.17391304
0.97333333
1


chr1:70338695
0.986607
82.3611111
0.96428571
1


chr19:18868002
0.986607
55.6818182
0.94642857
1


chr9:14041343
0.986607
86.1904762
0.96428571
1


chr10:76887324
0.986486
71.657754
0.94594595
1


chr19:7934351
0.986486
49.5961175
0.94594595
1


chr19:13644740
0.986486
55.2083333
0.98648649
1


chr2:5691280
0.986486
89.2857143
0.97297297
1


chr5:134550960
0.986486
59.1025641
0.97297297
1


chr12:95633568
0.986364
24.9482402
0.98181818
1


chr1:6460956
0.986301
50.9671993
0.98630137
1


chr16:17134583
0.986301
16.6666667
0.97260274
1


chr16:17134595
0.986301
8.69565217
0.97260274
1


chr16:61149835
0.986301
85.9375
0.97260274
1


chr19:4101376
0.986301
92.0807453
0.97260274
1


chr19:37692212
0.986301
97.3684211
0.97260274
1


chr6:1494847
0.986301
99.7641509
0.97260274
1


chr7:38178231
0.986301
4.2791762
0.97260274
1


chr7:71132295
0.986301
98.5915493
0.97260274
1


chr11:134072686
0.986111
59.6296296
0.95833333
1


chr16:2720277
0.986111
1.02040816
0.97222222
1


chr16:11345580
0.986111
6.9047619
0.95833333
1


chr17:29613358
0.986111
87.7777778
0.95555556
1


chr18:14867181
0.986111
20.1923077
0.97222222
1


chr19:3613344
0.986111
91.1538462
0.97222222
1


chr2:209772188
0.986111
23.9548495
0.98611111
1


chr6:34552991
0.986111
75.9090909
0.97222222
1


chr6:88962788
0.986111
93.3333333
0.97222222
1


chr12:105977085
0.985915
16.3333333
0.98591549
1


chr17:7479367
0.985915
4.62765957
0.97183099
1


chr17:21379559
0.985915
79.9498747
0.95774648
1


chr19:10502839
0.985915
4.63609172
0.98591549
1


chr19:39178093
0.985915
74.3421053
0.98591549
1


chr21:43313606
0.985915
59.9431818
0.97183099
1


chr22:31306646
0.985915
5.88678433
0.97183099
1


chr3:11717633
0.985915
50.0938967
0.97183099
1


chr3:139539693
0.985915
15.4761905
0.98591549
1


chr7:4730228
0.985915
59.0277778
0.97183099
1


chr4:154375969
0.985849
90.1785714
0.98113208
1
















TABLE 30







DNA methylation sites associated with SCLC-I











MethylationSite
AUC
threshold
specificity
sensitivity














chr1:1040462
1
87.4509804
1
1


chr1:1040475
1
90.3571429
1
1


chr1:1682754
1
69.6153846
1
1


chr1:6249894
1
56.8181818
1
1


chr1:6249902
1
65.9090909
1
1


chr1:6249914
1
66.8831169
1
1


chr1:6249917
1
70.4545455
1
1


chr1:12191832
1
79.7979798
1
1


chr1:15741578
1
8.57142857
1
1


chr1:16980570
1
94.4444444
1
1


chr1:16980579
1
71.7948718
1
1


chr1:16980593
1
94.4444444
1
1


chr1:18630506
1
82.5757576
1
1


chr1:20487144
1
10.7954545
1
1


chr1:21574155
1
60.3896104
1
1


chr1:23801501
1
77.8195489
1
1


chr1:24730777
1
26.8965517
1
1


chr1:24730787
1
60
1
1


chr1:24730788
1
57.2139303
1
1


chr1:24730796
1
44.1304348
1
1


chr1:24730797
1
51.6583748
1
1


chr1:25195867
1
87.1052632
1
1


chr1:31065986
1
4.4834308
1
1


chr1:36323440
1
8.07354117
1
1


chr1:39491967
1
3.74331551
1
1


chr1:43285575
1
49.2324561
1
1


chr1:43285577
1
51.8640351
1
1


chr1:43369421
1
87.3826903
1
1


chr1:89843439
1
84.4444444
1
1


chr1:89843473
1
92.2222222
1
1


chr1:145960916
1
7.57142857
1
1


chr1:153532886
1
83.1521739
1
1


chr1:153532890
1
89.4927536
1
1


chr1:156908050
1
97.5
1
1


chr1:163404039
1
52.5252525
1
1


chr1:163423088
1
63.125
1
1


chr1:163423133
1
67.5
1
1


chr1:163423188
1
77.540107
1
1


chr1:163423194
1
60.2240896
1
1


chr1:163423199
1
75.6493506
1
1


chr1:163546298
1
70.1929366
1
1


chr1:164136579
1
64.4409938
1
1


chr1:164136587
1
73.5714286
1
1


chr1:164136632
1
4.16666667
1
1


chr1:164236230
1
62.2159091
1
1


chr1:164236242
1
49.1477273
1
1


chr1:165235591
1
5.75016523
1
1


chr1:167796909
1
75
1
1


chr1:208601823
1
67.7071006
1
1


chr1:213771516
1
27.3026316
1
1


chr1:213820223
1
61.6135084
1
1


chr1:213861854
1
56.5789474
1
1


chr1:213861907
1
78.3648498
1
1


chr1:213910457
1
81.1011905
1
1


chr1:225962005
1
63.6029412
1
1


chr1:230322908
1
77.4725275
1
1


chr1:240992226
1
68.7782805
1
1


chr1:241128149
1
85.3571429
1
1


chr1:243916475
1
70.5032302
1
1


chr10:99431109
1
2.48144712
1
1


chr10:132518774
1
88.0952381
1
1


chr11:366066
1
17.6022176
1
1


chr11:438565
1
25.9972955
1
1


chr11:438607
1
62.5
1
1


chr11:726201
1
27.5641026
1
1


chr11:848890
1
83.7662338
1
1


chr11:848923
1
63.3333333
1
1


chr11:848927
1
26.7676768
1
1


chr11:848933
1
38.8888889
1
1


chr11:849115
1
86.1111111
1
1


chr11:849137
1
23.3766234
1
1


chr11:849141
1
56.547619
1
1


chr11:849142
1
86.1111111
1
1


chr11:849148
1
25.8333333
1
1


chr11:849149
1
78.968254
1
1


chr11:17734970
1
3.57142857
1
1


chr11:44566012
1
40.3743316
1
1


chr11:45922046
1
63.25
1
1


chr11:45922074
1
45.4285714
1
1


chr11:45922076
1
42.3469388
1
1


chr11:45922090
1
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1
1


chr19:4955146
1
81.7813765
1
1


chr19:6464556
1
88.8888889
1
1


chr19:6551811
1
76.4285714
1
1


chr19:6583884
1
60.3896104
1
1


chr19:7115981
1
51.0882353
1
1


chr19:7904264
1
4.85805861
1
1


chr19:9953412
1
76.1904762
1
1


chr19:9953424
1
83.6870027
1
1


chr19:9961699
1
95.8791209
1
1


chr19:9966503
1
70.3266788
1
1


chr19:9966579
1
58.4586466
1
1


chr19:9966586
1
62.6984127
1
1


chr19:9997385
1
58.3333333
1
1


chr19:10625441
1
7.60263053
1
1


chr19:10625699
1
12.9554656
1
1


chr19:11418683
1
13.3928571
1
1


chr19:13099153
1
85.6037152
1
1


chr19:13248768
1
83.974359
1
1


chr19:14433259
1
5.25641026
1
1


chr19:15195814
1
6.69642857
1
1


chr19:15195823
1
10.5555556
1
1


chr19:15195830
1
10.1010101
1
1


chr19:15195831
1
30.5194805
1
1


chr19:15195838
1
10.7142857
1
1


chr19:15195844
1
6.9047619
1
1


chr19:15195847
1
12.6984127
1
1


chr19:15195851
1
21.0653753
1
1


chr19:17041847
1
51.6666667
1
1


chr19:17251851
1
91.875
1
1


chr19:28293220
1
65.625
1
1


chr19:29892627
1
95.6481481
1
1


chr19:33260980
1
91.6666667
1
1


chr19:33393584
1
88.7362637
1
1


chr19:36008846
1
53.2388664
1
1


chr19:36009562
1
4.94623656
1
1


chr19:42242259
1
4.20634921
1
1


chr19:43757320
1
30
1
1


chr19:44796859
1
36.8421053
1
1


chr19:45444316
1
12.6984127
1
1


chr19:45598430
1
65.1515152
1
1


chr19:46016118
1
34.375
1
1


chr19:46016119
1
58.1196581
1
1


chr19:46016123
1
34.375
1
1


chr19:46016124
1
63.6752137
1
1


chr19:46016125
1
26.0416667
1
1


chr19:46016126
1
32.0512821
1
1


chr19:46016130
1
14.5833333
1
1


chr19:46016136
1
21.875
1
1


chr19:46016138
1
18.75
1
1


chr19:46016139
1
30.952381
1
1


chr19:46016142
1
41.4529915
1
1


chr19:46016144
1
38.5416667
1
1


chr19:46016145
1
62.7090301
1
1


chr19:46016146
1
26.6666667
1
1


chr19:46016147
1
37.6068376
1
1


chr19:46016148
1
30.2083333
1
1


chr19:46016149
1
28.2051282
1
1


chr19:46016465
1
9.82142857
1
1


chr19:48752569
1
12.5
1
1


chr19:48752624
1
8.98334794
1
1


chr19:48752637
1
9.44170772
1
1


chr19:48753115
1
7.39348371
1
1


chr19:48753117
1
11.1428571
1
1


chr19:48753159
1
15.7509158
1
1


chr19:48753363
1
78.604119
1
1


chr19:48753390
1
47.2222222
1
1


chr19:50417522
1
36.6071429
1
1


chr19:50418925
1
76.8115942
1
1


chr19:51030848
1
2.38095238
1
1


chr19:51077450
1
11.8055556
1
1


chr19:52028350
1
4.71491228
1
1


chr19:53991315
1
23.0113636
1
1


chr19:55374611
1
58.5227273
1
1


chr19:55554857
1
68.627451
1
1


chr2:3303753
1
6.97115385
1
1


chr2:4107720
1
10.1010101
1
1


chr2:4798818
1
43.75
1
1


chr2:6987052
1
89.2045455
1
1


chr2:7032109
1
80.952381
1
1


chr2:8457740
1
97.6190476
1
1


chr2:14507507
1
31.884058
1
1


chr2:25190664
1
53.90625
1
1


chr2:47369968
1
20.4273504
1
1









Sample Classification


In order to obtain the highest number of classified samples for the analysis of differential methylation, the results from the RNAseq and DNA methylation analysis were combined with a hierarchical approach in which RNAseq-based classification was used as principal classifier. For samples in which RNAseq-based classification was equivocal or in which RNAseq was not performed the SCLC subtype based on the DNA methylation-based predictor was used to gather a classification for the majority of samples.


Data Analysis


All analysis was performed in R v4.1.1. Binning of the genome was performed based on the BSgenome.Hsapiens.NCBI.GRCh38 database using a tile width of 100.000 bp cutting the last tile of each chromosome. DNA methylation across each tile was averaged excluding missing data. To analyse the genome-wide methylation per subtype, the mean methylation per tile per sample was further averaged per subtype. The rolling average of 500 bins (=50 Mbp) was calculated using the ‘rollmean’ function in the R zoo package.


In order to annotate the methylation sites to regions in the genome associated with genes, the annotatr package was used. The following regions were annotated based on the GRCh38 genome: “hg38_genes_promoters”, “hg38_genes_exons”, “hg38_genes_introns”, “hg38_genes_1to5kb”, “hg38_genes_5UTRs”, “hg38_genes_intergenic”, “hg38_genes_3UTRs”, “hg38_genes_firstexons”, “hg38_genes_intronexonboundaries”, “hg38_genes_exonintronboundaries”.


Association of DNA methylation sites or regions was performed using pROC. Cut-offs were calculated using Youden's J and sensitivity and specificity has been calculated based on the pre-calculated cut-off. For the calculations of differences, unless otherwise highlighted. Wilcoxon test was used with FDR correction for multiple testing using rstatix.


Figures were created using ggplot2 or ComplexHeatmap and Venn Diagrams with ggVennDiagram.


Xenograft Samples


Patient-derived xenograft models were prepared as published previously. Briefly, patients with a confirmed diagnosis of SCLC consented to the LAB10-0442 protocol at the MD Anderson Cancer Center. Circulating tumor cells (CTCs) were isolated using the RosetteSep CTC enrichment cocktail and isolated CTCs were mixed 1:1 with Matrigel and injected subcutaneously into the flank of NOD.Cg-Prkdcscid Il2rgtm1Wj1/SzJ mice.


Cell Line Samples


Cell lines were cultivated as published previously. Contamination with mycoplasma was tested regularly.


All of the methods disclosed and claimed herein can be made and executed without undue experimentation in light of the present disclosure. While the compositions and methods of this invention have been described in terms of certain embodiments, it will be apparent to those of skill in the art that variations may be applied to the methods and in the steps or in the sequence of steps of the method described herein without departing from the concept, spirit and scope of the invention. All such similar substitutes and modifications apparent to those skilled in the art are deemed to be within the spirit, scope and concept of the invention as defined by the appended claims.


REFERENCES

The following references, and those cited elsewhere herein, to the extent that they provide exemplary procedural or other details supplementary to those set forth herein, are specifically incorporated herein by reference.

  • 1. Byers, L. A. & Rudin, C. M. Small cell lung cancer: where do we go from here? Cancer 121, 664-672 (2015).
  • 2. Horn. L., et al. First-Line Atezolizumab plus Chemotherapy in Extensive-Stage Small-Cell Lung Cancer. N Engl J Med 379, 2220-2229 (2018).
  • 3. Paz-Ares, L., et al. Durvalumab plus platinum-etoposide versus platinum-etoposide in first-line treatment of extensive-stage small-cell lung cancer (CASPIAN): a randomised, controlled, open-label, phase 3 trial. Lancet 394, 1929-1939 (2019).
  • 4. Uprety, D., Remon, J. & Adjei, A. A. All That Glitters Is Not Gold: The Story of Rovalpituzumab Tesirine in SCLC. J Thorac Oncol 16, 1429-1433 (2021).
  • 5. Byers, L. A., Chiappori, A. & Smit, M.-A. D. Phase 1 study of AMG 119, a chimeric antigen receptor (CAR) T cell therapy targeting DLL3, in patients with relapsed/refractory small cell lung cancer (SCLC). J. Clin. Oncol. 37, 1-TPS8576 (2019).
  • 6. Hipp, S., et al. A Bispecific DLL3/CD3 IgG-Like T-Cell Engaging Antibody Induces Antitumor Responses in Small Cell Lung Cancer. Clin Cancer Res 26, 5258-5268 (2020).
  • 7. Pietanza, M. C., et al. Randomized, Double-Blind, Phase II Study of Temozolomide in Combination With Either Veliparib or Placebo in Patients With Relapsed-Sensitive or Refractory Small-Cell Lung Cancer. J Clin Oncol 36, 2386-2394 (2018).
  • 8. Howlader, N., et al. The Effect of Advances in Lung-Cancer Treatment on Population Mortality. N Engl J Med 383, 640-649 (2020).
  • 9. Rudin, C. M., et al. Molecular subtypes of small cell lung cancer: a synthesis of human and mouse model data. Nat Rev Cancer 19, 289-297 (2019).
  • 10. Baine, M. K., et al. SCLC Subtypes Defined by ASCL1. NEUROD1, POU2F3, and YAP1: A Comprehensive Immunohistochemical and Histopathologic Characterization. J Thorac Oncol 15, 1823-1835 (2020).
  • 11. Gay, C. M., et al. Patterns of transcription factor programs and immune pathway activation define four major subtypes of SCLC with distinct therapeutic vulnerabilities. Cancer Cell 39, 346-360 e347 (2021).
  • 12. Schwendenwein, A., et al. Molecular profiles of small cell lung cancer subtypes: therapeutic implications. Mol Ther Oncolytics 20, 470-483 (2021).
  • 13. National Comprehensive Cancer Network. Small Cell Lung Cancer (2022). Vol. 2021 (2021).
  • 14. Kalari, S., Jung, M., Kernstine, K. H., Takahashi, T. & Pfeifer, G. P. The DNA methylation landscape of small cell lung cancer suggests a differentiation defect of neuroendocrine cells. Oncogene 32, 3559-3568 (2013).
  • 15. Krushkal, J., et al. Epigenome-wide DNA methylation analysis of small cell lung cancer cell lines suggests potential chemotherapy targets. Clin Epigenetics 12, 93 (2020).
  • 16. Zhang, Y., et al. Pan-cancer circulating tumor DNA detection in over 10,000 Chinese patients. Nat Commun 12, 11 (2021).
  • 17. Gaga, M., et al. Validation of Lung EpiCheck, a novel methylation-based blood assay, for the detection of lung cancer in European and Chinese high-risk individuals. Eur Respir J 57(2021).
  • 18. George, J., et al. Comprehensive genomic profiles of small cell lung cancer. Nature 524, 47-53 (2015).
  • 19. Tlemsani, C., et al. SCLC-CellMiner: A Resource for Small Cell Lung Cancer Cell Line Genomics and Pharmacology Based on Genomic Signatures. Cell Rep 33, 108296 (2020).
  • 20. Iorio, F., et al. A Landscape of Pharmacogenomic Interactions in Cancer. Cell 166, 740-754 (2016).
  • 21. Van Paemel, R., et al. Genome-wide study of the effect of blood collection tubes on the cell-free DNA methylome. Epigenetics 16, 797-807 (2021).
  • 22. Tang, M., et al. The histologic phenotype of lung cancers is associated with transcriptomic features rather than genomic characteristics. Nat Commun 12, 7081 (2021).
  • 23. Sato, Y., et al. Integrated Immunohistochemical Study on Small-Cell Carcinoma of the Lung Focusing on Transcription and Co-Transcription Factors. Diagnostics (Basel) 10(2020).
  • 24. Stewart, C. A., et al. Single-cell analyses reveal increased intratumoral heterogeneity after the onset of therapy resistance in small-cell lung cancer. Nat Cancer 1, 423-436 (2020).
  • 25. Poirier, J. T., et al. DNA methylation in small cell lung cancer defines distinct disease subtypes and correlates with high expression of EZH2. Oncogene 34, 5869-5878 (2015).
  • 26. Lin. S. H., et al. Genes suppressed by DNA methylation in non-small cell lung cancer reveal the epigenetics of epithelial-mesenchymal transition. BMC Genomics 15, 1079 (2014).
  • 27. Wang, Z., et al. Complex impact of DNA methylation on transcriptional dysregulation across 22 human cancer types. Nucleic Acids Res 48, 2287-2302 (2020).
  • 28. Liu, M. C., et al. Sensitive and specific multi-cancer detection and localization using methylation signatures in cell-free DNA. Ann Oncol 31, 745-759 (2020).
  • 29. Kilgour, E., Rothwell, D. G., Brady, G. & Dive, C. Liquid Biopsy-Based Biomarkers of Treatment Response and Resistance. Cancer Cell 37, 485-495 (2020).

Claims
  • 1. A method of treating a subject for small cell lung cancer (SCLC), the method comprising administering a BCL2 inhibitor or a DLL3-targeted therapy to a subject having tumor DNA with differential methylation at one or more methylation sites selected from the methyation sites of Table 2, Table 7, Table 15, Table 20, and Table 27 compared to a reference or control sample.
  • 2. The method of claim 1, wherein the one or more methylation sites are 2 or more methylation sites selected from the methyation sites of Table 2, Table 7, Table 15, Table 20, and Table 27.
  • 3. The method of claim 1, wherein the one or more methylation sites are 3 or more methylation sites selected from the methyation sites of Table 2, Table 7, Table 15, Table 20, and Table 27.
  • 4. The method of claim 1, wherein the one or more methylation sites are 4 or more methylation sites selected from the methyation sites of Table 2, Table 7, Table 15, Table 20, and Table 27.
  • 5. The method of claim 1, wherein the one or more methylation sites are 5 or more methylation sites selected from the methyation sites of Table 2, Table 7, Table 15, Table 20, and Table 27.
  • 6. The method of claim 1, wherein the one or more methylation sites are 10 or more methylation sites selected from the methyation sites of Table 2, Table 7, Table 15, Table 20, and Table 27.
  • 7. The method of claim 1, wherein the one or more methylation sites are twenty or more methylation sites selected from the methyation sites of Table 2, Table 7, Table 15, Table 20, and Table 27.
  • 8. The method of claim 1, wherein the one or more methylation sites are fifty or more methylation sites selected from the methyation sites of Table 2, Table 7, Table 15, Table 20, and Table 27.
  • 9. The method of claim 1, wherein the one or more methylation sites are one or more methylation sites of Table 2.
  • 10. The method of claim 1, wherein the one or more methylation sites are 2 or more methylation sites of Table 2.
  • 11. The method of claim 1, wherein the one or more methylation sites are 3 or more methylation sites of Table 2.
  • 12. The method of claim 1, wherein the one or more methylation sites are 4 or more methylation sites of Table 2.
  • 13. The method of claim 1, wherein the one or more methylation sites are 5 or more methylation sites of Table 2.
  • 14. The method of claim 1, wherein the one or more methylation sites are 10 or more methylation sites of Table 2.
  • 15. The method of claim 1, wherein the one or more methylation sites are all of the methylation sites of Table 2.
  • 16. The method of claim 1, wherein the one or more methylation sites are one or more methylation sites of Table 7.
  • 17. The method of claim 1, wherein the one or more methylation sites are 2 or more methylation sites of Table 7.
  • 18. The method of claim 1, wherein the one or more methylation sites are 3 or more methylation sites of Table 7.
  • 19. The method of claim 1, wherein the one or more methylation sites are 4 or more methylation sites of Table 7.
  • 20. The method of claim 1, wherein the one or more methylation sites are one or more methylation sites of Table 7.
  • 21. The method of claim 1, wherein the one or more methylation sites are 10 or more methylation sites of Table 7.
  • 22. The method of claim 1, wherein the one or more methylation sites are all of the methylation sites of Table 7.
  • 23. The method of claim 1, wherein the one or more methylation sites are one or more methylation sites of Table 15.
  • 24. The method of claim 1, wherein the one or more methylation sites are 2 or more methylation sites of Table 15.
  • 25. The method of claim 1, wherein the one or more methylation sites are 3 or more methylation sites of Table 15.
  • 26. The method of claim 1, wherein the one or more methylation sites are 4 or more methylation sites of Table 15.
  • 27. The method of claim 1, wherein the one or more methylation sites are 5 or more methylation sites of Table 15.
  • 28. The method of claim 1, wherein the one or more methylation sites are 10 or more methylation sites of Table 15.
  • 29. The method of claim 1, wherein the one or more methylation sites are all of the methylation sites of Table 15.
  • 30. The method of claim 1, wherein the one or more methylation sites are one or more methylation sites of Table 20.
  • 31. The method of claim 1, wherein the one or more methylation sites are 2 or more methylation sites of Table 20.
  • 32. The method of claim 1, wherein the one or more methylation sites are 3 or more methylation sites of Table 20.
  • 33. The method of claim 1, wherein the one or more methylation sites are 4 or more methylation sites of Table 20.
  • 34. The method of claim 1, wherein the one or more methylation sites are 5 or more methylation sites of Table 20.
  • 35. The method of claim 1, wherein the one or more methylation sites are 10 or more methylation sites of Table 20.
  • 36. The method of claim 1, wherein the one or more methylation sites are all of the methylation sites of Table 20.
  • 37. The method of claim 1, wherein the one or more methylation sites are one or more methylation sites of Table 27.
  • 38. The method of claim 1, wherein the one or more methylation sites are 2 or more methylation sites of Table 27.
  • 39. The method of claim 1, wherein the one or more methylation sites are 3 or more methylation sites of Table 27.
  • 40. The method of claim 1, wherein the one or more methylation sites are 4 or more methylation sites of Table 27.
  • 41. The method of claim 1, wherein the one or more methylation sites are 5 or more methylation sites of Table 27.
  • 42. The method of claim 1, wherein the one or more methylation sites are 10 or more methylation sites of Table 27.
  • 43. The method of claim 1, wherein the one or more methylation sites are all of the methylation sites of Table 27.
  • 44. The method of any of claims 1-43, wherein the tumor DNA is ctDNA.
  • 45. The method of any of claims 1-22, wherein the method comprises administering to the subject the BCL2 inhibitor.
  • 46. The method of claim 45, wherein the BCL2 inhibitor is ABT-737 or navitoclax.
  • 47. The method of any of claims 1-45, wherein the method comprises administering to the subject the DLL3-targeted therapeutic.
  • 48. The method of claim 47, wherein the DLL3-targeted therapeutic comprises an anti-DLL3 antibody or fragment thereof.
  • 49. The method of claim 48, wherein the anti-DLL3 antibody or fragment thereof is rovalpituzumab.
  • 50. The method of claim 47, wherein the DLL3-targeted therapeutic is an antibody-drug conjugate.
  • 51. The method of claim 50, wherein the antibody-drug conjugate is rovalpituzumab tesirine.
  • 52. The method of claim 47, wherein the DLL3-targeted therapeutic is a DLL3-targeted cellular therapy.
  • 53. The method of claim 52, wherein the DLL3-targeted cellular therapy is a DLL3-targeted chimeric antigen receptor T-cell.
  • 54. The method of any of claims 1-52, further comprising administering to the subject an additional cancer therapy.
  • 55. The method of claim 54, wherein the additional cancer therapy comprises chemotherapy, radiotherapy, immunotherapy, or a combination thereof.
  • 56. The method of any of claims 1-55, wherein the subject was previously treated for SCLC.
  • 57. The method of claim 1-56, wherein the subject was resistant to the previous treatment.
  • 58. The method of any of claims 1-57, wherein the subject was determined to have SCLC-A based on the analysis of the tumor DNA.
  • 59. The method of any of claims 1-58, wherein the subject was further determined, from the analysis of the tumor DNA from the subject, to have differential methylation of one or more methylation sites of Table 13 compared to the reference or control sample.
  • 60. The method of any of claims 1-59, wherein the reference or control sample is a DNA sample obtained from healthy cells from the subject.
  • 61. The method of any of claims 1-59, wherein the reference or control sample is a DNA sample obtained from healthy cells from a reference subject.
  • 62. A method of treating a subject for SCLC, the method comprising administering an AURK inhibitor to a subject having tumor DNA with differential methylation at one or more methylation sites selected from the methylation sites of Table 3, Table 8, Table 16, Table 21, and Table 28 compared to a reference or control sample.
  • 63. The method of claim 62, wherein the one or more methylation sites are 2 or more methylation sites selected from the methyation sites of Table 3, Table 8, Table 16, Table 21, and Table 28.
  • 64. The method of claim 62, wherein the one or more methylation sites are 3 or more methylation sites selected from the methyation sites of Table 3, Table 8, Table 16, Table 21, and Table 28.
  • 65. The method of claim 62, wherein the one or more methylation sites are 4 or more methylation sites selected from the methyation sites of Table 3, Table 8, Table 16, Table 21, and Table 28.
  • 66. The method of claim 62, wherein the one or more methylation sites are 5 or more methylation sites selected from the methyation sites of Table 3, Table 8, Table 16, Table 21, and Table 28.
  • 67. The method of claim 62, wherein the one or more methylation sites are 10 or more methylation sites selected from the methyation sites of Table 3, Table 8, Table 16, Table 21, and Table 28.
  • 68. The method of claim 62, wherein the one or more methylation sites are twenty or more methylation sites selected from the methyation sites of Table 3, Table 8, Table 16, Table 21, and Table 28.
  • 69. The method of claim 62, wherein the one or more methylation sites are fifty or more methylation sites selected from the methyation sites of Table 3, Table 8, Table 16, Table 21, and Table 28.
  • 70. The method of claim 62, wherein the one or more methylation sites are one or more methylation sites of Table 3.
  • 71. The method of claim 62, wherein the one or more methylation sites are 2 or more methylation sites of Table 3.
  • 72. The method of claim 62, wherein the one or more methylation sites are 3 or more methylation sites of Table 3.
  • 73. The method of claim 62, wherein the one or more methylation sites are 4 or more methylation sites of Table 3.
  • 74. The method of claim 62, wherein the one or more methylation sites are 5 or more methylation sites of Table 3.
  • 75. The method of claim 62, wherein the one or more methylation sites are 10 or more methylation sites of Table 3.
  • 76. The method of claim 62, wherein the one or more methylation sites are all of the methylation sites of Table 3.
  • 77. The method of claim 62, wherein the one or more methylation sites are one or more methylation sites of Table 8.
  • 78. The method of claim 62, wherein the one or more methylation sites are 2 or more methylation sites of Table 8.
  • 79. The method of claim 62, wherein the one or more methylation sites are 3 or more methylation sites of Table 8.
  • 80. The method of claim 62, wherein the one or more methylation sites are 4 or more methylation sites of Table 8.
  • 81. The method of claim 62, wherein the one or more methylation sites are 5 or more methylation sites of Table 8.
  • 82. The method of claim 62, wherein the one or more methylation sites are 10 or more methylation sites of Table 8.
  • 83. The method of claim 62, wherein the one or more methylation sites are all of the methylation sites of Table 8.
  • 84. The method of claim 62, wherein the one or more methylation sites are one or more methylation sites of Table 16.
  • 85. The method of claim 62, wherein the one or more methylation sites are 2 or more methylation sites of Table 16.
  • 86. The method of claim 62, wherein the one or more methylation sites are 3 or more methylation sites of Table 16.
  • 87. The method of claim 62, wherein the one or more methylation sites are 4 or more methylation sites of Table 16.
  • 88. The method of claim 62, wherein the one or more methylation sites are 5 or more methylation sites of Table 16.
  • 89. The method of claim 62, wherein the one or more methylation sites are 10 or more methylation sites of Table 16.
  • 90. The method of claim 62, wherein the one or more methylation sites are all of the methylation sites of Table 16.
  • 91. The method of claim 62, wherein the one or more methylation sites are one or more methylation sites of Table 21.
  • 92. The method of claim 62, wherein the one or more methylation sites are 2 or more methylation sites of Table 21.
  • 93. The method of claim 62, wherein the one or more methylation sites are 3 or more methylation sites of Table 21.
  • 94. The method of claim 62, wherein the one or more methylation sites are 4 or more methylation sites of Table 21.
  • 95. The method of claim 62, wherein the one or more methylation sites are 5 or more methylation sites of Table 21.
  • 96. The method of claim 62, wherein the one or more methylation sites are 10 or more methylation sites of Table 21.
  • 97. The method of claim 62, wherein the one or more methylation sites are all of the methylation sites of Table 21.
  • 98. The method of claim 62, wherein the one or more methylation sites are one or more methylation sites of Table 28.
  • 99. The method of claim 62, wherein the one or more methylation sites are 2 or more methylation sites of Table 28.
  • 100. The method of claim 62, wherein the one or more methylation sites are 3 or more methylation sites of Table 28.
  • 101. The method of claim 62, wherein the one or more methylation sites are 4 or more methylation sites of Table 28.
  • 102. The method of claim 62, wherein the one or more methylation sites are 5 or more methylation sites of Table 28.
  • 103. The method of claim 62, wherein the one or more methylation sites are 10 or more methylation sites of Table 28.
  • 104. The method of claim 62, wherein the one or more methylation sites are all of the methylation sites of Table 28.
  • 105. The method of any of claims 62-104, wherein the tumor DNA is ctDNA.
  • 106. The method of any of claims 62-105, wherein the AURK inhibitor is CYC-116, alisertib, or AS-703569.
  • 107. The method of any of claims 62-106, further comprising administering to the subject an additional cancer therapy.
  • 108. The method of claim 107, wherein the additional cancer therapy comprises chemotherapy, radiotherapy, immunotherapy, or a combination thereof.
  • 109. The method of any of claims 62-108, wherein the subject was previously treated for SCLC.
  • 110. The method of claim 109, wherein the subject was resistant to the previous treatment.
  • 111. The method of any of claims 62-110, wherein the subject was determined to have SCLC-N based on the analysis of the tumor DNA.
  • 112. The method of any of claims 62-111, wherein the subject was further determined, from the analysis of the tumor DNA from the subject, to have differential methylation of one or more methylation sites of Table 13 compared to the reference or control sample.
  • 113. The method of any of claims 62-112, wherein the reference or control sample is a DNA sample obtained from healthy cells from the subject.
  • 114. The method of any of claims 62-112, wherein the reference or control sample is a DNA sample obtained from healthy cells from a reference subject.
  • 115. A method of treating a subject for SCLC, the method comprising administering a platinum-based chemotherapeutic agent, a PARP inhibitor, an anti-metabolite, or a nucleoside analog to a subject having tumor DNA with differential methylation at one or more methylation sites selected from the methylation sites of Table 4, Table 9, Table 17, Table 22, and Table 29 compared to a reference or control sample.
  • 116. The method of claim 115, wherein the one or more methylation sites are 2 or more methylation sites selected from the methyation sites of Table 4, Table 9, Table 17, Table 22, and Table 29.
  • 117. The method of claim 115, wherein the one or more methylation sites are 3 or more methylation sites selected from the methyation sites of Table 4, Table 9, Table 17, Table 22, and Table 29.
  • 118. The method of claim 115, wherein the one or more methylation sites are 4 or more methylation sites selected from the methyation sites of Table 4, Table 9, Table 17, Table 22, and Table 29.
  • 119. The method of claim 115, wherein the one or more methylation sites are 5 or more methylation sites selected from the methyation sites of Table 4, Table 9, Table 17, Table 22, and Table 29.
  • 120. The method of claim 115, wherein the one or more methylation sites are 10 or more methylation sites selected from the methyation sites of Table 4, Table 9, Table 17, Table 22, and Table 29.
  • 121. The method of claim 115, wherein the one or more methylation sites are twenty or more methylation sites selected from the methyation sites of Table 4, Table 9, Table 17, Table 22, and Table 29.
  • 122. The method of claim 115, wherein the one or more methylation sites are fifty or more methylation sites selected from the methyation sites of Table 4, Table 9, Table 17, Table 22, and Table 29.
  • 123. The method of claim 115, wherein the one or more methylation sites are one or more methylation sites of Table 4.
  • 124. The method of claim 115, wherein the one or more methylation sites are 2 or more methylation sites of Table 4.
  • 125. The method of claim 115, wherein the one or more methylation sites are 3 or more methylation sites of Table 4.
  • 126. The method of claim 115, wherein the one or more methylation sites are 4 or more methylation sites of Table 4.
  • 127. The method of claim 115, wherein the one or more methylation sites are 5 or more methylation sites of Table 4.
  • 128. The method of claim 115, wherein the one or more methylation sites are 10 or more methylation sites of Table 4.
  • 129. The method of claim 115, wherein the one or more methylation sites are all of the methylation sites of Table 4.
  • 130. The method of claim 115, wherein the one or more methylation sites are one or more methylation sites of Table 9.
  • 131. The method of claim 115, wherein the one or more methylation sites are 2 or more methylation sites of Table 9.
  • 132. The method of claim 115, wherein the one or more methylation sites are 3 or more methylation sites of Table 9.
  • 133. The method of claim 115, wherein the one or more methylation sites are 4 or more methylation sites of Table 9.
  • 134. The method of claim 115, wherein the one or more methylation sites are 5 or more methylation sites of Table 9.
  • 135. The method of claim 115, wherein the one or more methylation sites are 10 or more methylation sites of Table 9.
  • 136. The method of claim 115, wherein the one or more methylation sites are all of the methylation sites of Table 9.
  • 137. The method of claim 115, wherein the one or more methylation sites are one or more methylation sites of Table 17.
  • 138. The method of claim 115, wherein the one or more methylation sites are 2 or more methylation sites of Table 17.
  • 139. The method of claim 115, wherein the one or more methylation sites are 3 or more methylation sites of Table 17.
  • 140. The method of claim 115, wherein the one or more methylation sites are 4 or more methylation sites of Table 17.
  • 141. The method of claim 115, wherein the one or more methylation sites are 5 or more methylation sites of Table 17.
  • 142. The method of claim 115, wherein the one or more methylation sites are 10 or more methylation sites of Table 17.
  • 143. The method of claim 115, wherein the one or more methylation sites are all of the methylation sites of Table 17.
  • 144. The method of claim 115, wherein the one or more methylation sites are one or more methylation sites of Table 22.
  • 145. The method of claim 115, wherein the one or more methylation sites are 2 or more methylation sites of Table 22.
  • 146. The method of claim 115, wherein the one or more methylation sites are 3 or more methylation sites of Table 22.
  • 147. The method of claim 115, wherein the one or more methylation sites are 4 or more methylation sites of Table 22.
  • 148. The method of claim 115, wherein the one or more methylation sites are 5 or more methylation sites of Table 22.
  • 149. The method of claim 115, wherein the one or more methylation sites are 10 or more methylation sites of Table 22.
  • 150. The method of claim 115, wherein the one or more methylation sites are all of the methylation sites of Table 22.
  • 151. The method of claim 115, wherein the one or more methylation sites are one or more methylation sites of Table 29.
  • 152. The method of claim 115, wherein the one or more methylation sites are 2 or more methylation sites of Table 29.
  • 153. The method of claim 115, wherein the one or more methylation sites are 3 or more methylation sites of Table 29.
  • 154. The method of claim 115, wherein the one or more methylation sites are 4 or more methylation sites of Table 29.
  • 155. The method of claim 115, wherein the one or more methylation sites are 5 or more methylation sites of Table 29.
  • 156. The method of claim 115, wherein the one or more methylation sites are 10 or more methylation sites of Table 29.
  • 157. The method of claim 115, wherein the one or more methylation sites are all of the methylation sites of Table 29.
  • 158. The method of any of claims 115-157, wherein the tumor DNA is ctDNA.
  • 159. The method of any of claims 115-136, wherein the method comprises administering to the subject the platinum-containing chemotherapeutic agent.
  • 160. The method of claim 159, wherein the platinum-containing chemotherapeutic agent is cisplatin, carboplatin, oxaliplatin, nedaplatin, picoplatin, or satraplatin.
  • 161. The method of any of claims 115-136, wherein the method comprises administering to the subject the PARP inhibitor.
  • 162. The method of claim 161, wherein the PARP inhibitor is talazoparib, olaparib, niraparib, AZD-2461, or rucaparib.
  • 163. The method of any of claims 115-136, wherein the method comprises administering to the subject the anti-metabolite.
  • 164. The method of claim 163, wherein the anti-metabolite is pemetrexed, methotrexate, or pralatrexate.
  • 165. The method of any of claims 115-136, wherein the method comprises administering to the subject the nucleoside analog.
  • 166. The method of claim 165, wherein the nucleoside analog is floxuridine, cytarabine, clofarabine, or fludarabine.
  • 167. The method of any of claims 115-166, further comprising administering to the subject an additional cancer therapy.
  • 168. The method of claim 167, wherein the additional cancer therapy comprises chemotherapy, radiotherapy, immunotherapy, or a combination thereof.
  • 169. The method of any of claims 115-168, wherein the subject was previously treated for SCLC.
  • 170. The method of claim 169, wherein the subject was resistant to the previous treatment.
  • 171. The method of any of claims 115-170, wherein the subject was determined to have SCLC-N based on the analysis of the tumor DNA.
  • 172. The method of any of claims 115-171, wherein the subject was further determined, from the analysis of the tumor DNA from the subject, to have differential methylation of one or more methylation sites of Table 13 compared to the reference or control sample.
  • 173. The method of any of claims 115-172, wherein the reference or control sample is a DNA sample obtained from healthy cells from the subject.
  • 174. The method of any of claims 115-172, wherein the reference or control sample is a DNA sample obtained from healthy cells from a reference subject.
  • 175. A method of treating a subject for SCLC, the method comprising administering an immunotherapy to a subject having tumor DNA with differential methylation at one or more methylation sites selected from the methylation sites of Table 5, Table 10, Table 18, Table 23, and Table 30 compared to a reference or control sample.
  • 176. The method of claim 175, wherein the one or more methylation sites are 2 or more methylation sites selected from the methyation sites of Table 5, Table 10, Table 18, Table 23, and Table 30.
  • 177. The method of claim 175, wherein the one or more methylation sites are 3 or more methylation sites selected from the methyation sites of Table 5, Table 10, Table 18, Table 23, and Table 30.
  • 178. The method of claim 175, wherein the one or more methylation sites are 4 or more methylation sites selected from the methyation sites of Table 5, Table 10, Table 18, Table 23, and Table 30.
  • 179. The method of claim 175, wherein the one or more methylation sites are 5 or more methylation sites selected from the methyation sites of Table 5, Table 10, Table 18, Table 23, and Table 30.
  • 180. The method of claim 175, wherein the one or more methylation sites are 5 or more methylation sites selected from the methyation sites of Table 5, Table 10, Table 18, Table 23, and Table 30.
  • 181. The method of claim 175, wherein the one or more methylation sites are 10 or more methylation sites selected from the methyation sites of Table 5, Table 10, Table 18, Table 23, and Table 30.
  • 182. The method of claim 175, wherein the one or more methylation sites are twenty or more methylation sites selected from the methyation sites of Table 5, Table 10, Table 18, Table 23, and Table 30.
  • 183. The method of claim 175, wherein the one or more methylation sites are fifty or more methylation sites selected from the methyation sites of Table 5, Table 10, Table 18, Table 23, and Table 30.
  • 184. The method of claim 175, wherein the one or more methylation sites are one or more methylation sites of Table 5.
  • 185. The method of claim 175, wherein the one or more methylation sites are 2 or more methylation sites of Table 5.
  • 186. The method of claim 175, wherein the one or more methylation sites are 3 or more methylation sites of Table 5.
  • 187. The method of claim 175, wherein the one or more methylation sites are 4 or more methylation sites of Table 5.
  • 188. The method of claim 175, wherein the one or more methylation sites are 5 or more methylation sites of Table 5.
  • 189. The method of claim 175, wherein the one or more methylation sites are 10 or more methylation sites of Table 5.
  • 190. The method of claim 175, wherein the one or more methylation sites are all of the methylation sites of Table 5.
  • 191. The method of claim 175, wherein the one or more methylation sites are one or more methylation sites of Table 10.
  • 192. The method of claim 175, wherein the one or more methylation sites are 2 or more methylation sites of Table 10.
  • 193. The method of claim 175, wherein the one or more methylation sites are 3 or more methylation sites of Table 10.
  • 194. The method of claim 175, wherein the one or more methylation sites are 4 or more methylation sites of Table 10.
  • 195. The method of claim 175, wherein the one or more methylation sites are 5 or more methylation sites of Table 10.
  • 196. The method of claim 175, wherein the one or more methylation sites are 10 or more methylation sites of Table 10.
  • 197. The method of claim 175, wherein the one or more methylation sites are all of the methylation sites of Table 10.
  • 198. The method of claim 175, wherein the one or more methylation sites are one or more methylation sites of Table 18.
  • 199. The method of claim 175, wherein the one or more methylation sites are 2 or more methylation sites of Table 18.
  • 200. The method of claim 175, wherein the one or more methylation sites are 3 or more methylation sites of Table 18.
  • 201. The method of claim 175, wherein the one or more methylation sites are 4 or more methylation sites of Table 18.
  • 202. The method of claim 175, wherein the one or more methylation sites are 5 or more methylation sites of Table 18.
  • 203. The method of claim 175, wherein the one or more methylation sites are 10 or more methylation sites of Table 18.
  • 204. The method of claim 175, wherein the one or more methylation sites are all of the methylation sites of Table 18.
  • 205. The method of claim 175, wherein the one or more methylation sites are one or more methylation sites of Table 23.
  • 206. The method of claim 175, wherein the one or more methylation sites are 2 or more methylation sites of Table 23.
  • 207. The method of claim 175, wherein the one or more methylation sites are 3 or more methylation sites of Table 23.
  • 208. The method of claim 175, wherein the one or more methylation sites are 4 or more methylation sites of Table 23.
  • 209. The method of claim 175, wherein the one or more methylation sites are 5 or more methylation sites of Table 23.
  • 210. The method of claim 175, wherein the one or more methylation sites are 10 or more methylation sites of Table 23.
  • 211. The method of claim 175, wherein the one or more methylation sites are all of the methylation sites of Table 23.
  • 212. The method of claim 175, wherein the one or more methylation sites are one or more methylation sites of Table 30.
  • 213. The method of claim 175, wherein the one or more methylation sites are 2 or more methylation sites of Table 30.
  • 214. The method of claim 175, wherein the one or more methylation sites are 3 or more methylation sites of Table 30.
  • 215. The method of claim 175, wherein the one or more methylation sites are 4 or more methylation sites of Table 30.
  • 216. The method of claim 175, wherein the one or more methylation sites are 5 or more methylation sites of Table 30.
  • 217. The method of claim 175, wherein the one or more methylation sites are 10 or more methylation sites of Table 30.
  • 218. The method of claim 175, wherein the one or more methylation sites are all of the methylation sites of Table 30.
  • 219. The method of any of claims 175-218, wherein the tumor DNA is ctDNA.
  • 220. The method of any of claims 175-219, wherein the immunotherapy is an immune checkpoint inhibitor therapy.
  • 221. The method of any of claims 175-220, further comprising administering to the subject an additional cancer therapy.
  • 222. The method of claim 221, wherein the additional cancer therapy comprises chemotherapy, radiotherapy, immunotherapy, or a combination thereof.
  • 223. The method of any of claims 175-222, wherein the subject was previously treated for SCLC.
  • 224. The method of claim 223, wherein the subject was resistant to the previous treatment.
  • 225. The method of any of claims 175-224, wherein the subject was determined to have SCLC-I based on the analysis of the tumor DNA.
  • 226. The method of any of claims 175-225, wherein the subject was further determined, from the analysis of the tumor DNA from the subject, to have differential methylation of one or more methylation sites of Table 13 compared to the reference or control sample.
  • 227. The method of any of claims 175-226, wherein the reference or control sample is a DNA sample obtained from healthy cells from the subject.
  • 228. The method of any of claims 175-226, wherein the reference or control sample is a DNA sample obtained from healthy cells from a reference subject.
  • 229. A method for classifying a subject having small cell lung cancer (SCLC), the method comprising: (a) determining, from DNA from the subject, a methylation status of one or more methylation sites selected from the methylation sites of Tables 1-10, 15-18, 20-23, and 27-30; and(b) classifying the subject as having SCLC-A, SCLC-N, SCLC-P, or SCLC-I based on the methylation status of the one or more methylation sites.
  • 230. The method of claim 229, wherein (b) comprises classifying the subject as having SCLC-A.
  • 231. The method of claim 230, wherein the one or more methylation sites are one or more methylation sites selected from the methylation sites of Table 2, Table 7, Table 15, Table 20, and Table 27.
  • 232. The method of claim 230, wherein the one or more methylation sites are 2 or more methylation sites selected from the methylation sites of Table 2, Table 7, Table 15, Table 20, and Table 27.
  • 233. The method of claim 230, wherein the one or more methylation sites are 3 or more methylation sites selected from the methylation sites of Table 2, Table 7, Table 15, Table 20, and Table 27.
  • 234. The method of claim 230, wherein the one or more methylation sites are 4 or more methylation sites selected from the methylation sites of Table 2, Table 7, Table 15, Table 20, and Table 27.
  • 235. The method of claim 232, wherein the one or more methylation sites are 5 or more methylation sites selected from the methyation sites of Table 2, Table 7, Table 15, Table 20, and Table 27.
  • 236. The method of claim 232, wherein the one or more methylation sites are 10 or more methylation sites selected from the methyation sites of Table 2, Table 7, Table 15, Table 20, and Table 27.
  • 237. The method of claim 232, wherein the one or more methylation sites are twenty or more methylation sites selected from the methyation sites of Table 2, Table 7, Table 15, Table 20, and Table 27.
  • 238. The method of claim 232, wherein the one or more methylation sites are fifty or more methylation sites selected from the methyation sites of Table 2, Table 7, Table 15, Table 20, and Table 27.
  • 239. The method of claim 230, wherein the one or more methylation sites are one or more methylation sites of Table 2.
  • 240. The method of claim 230, wherein the one or more methylation sites are 2 or more methylation sites of Table 2.
  • 241. The method of claim 230, wherein the one or more methylation sites are 3 or more methylation sites of Table 2.
  • 242. The method of claim 230, wherein the one or more methylation sites are 4 or more methylation sites of Table 2.
  • 243. The method of claim 230, wherein the one or more methylation sites are 5 or more methylation sites of Table 2.
  • 244. The method of claim 230, wherein the one or more methylation sites are 10 or more methylation sites of Table 2.
  • 245. The method of claim 230, wherein the one or more methylation sites are all of the methylation sites of Table 2.
  • 246. The method of claim 230, wherein the one or more methylation sites are one or more methylation sites of Table 7.
  • 247. The method of claim 230, wherein the one or more methylation sites are 2 or more methylation sites of Table 7.
  • 248. The method of claim 230, wherein the one or more methylation sites are 3 or more methylation sites of Table 7.
  • 249. The method of claim 230, wherein the one or more methylation sites are 4 or more methylation sites of Table 7.
  • 250. The method of claim 230, wherein the one or more methylation sites are 5 or more methylation sites of Table 7.
  • 251. The method of claim 230, wherein the one or more methylation sites are 10 or more methylation sites of Table 7.
  • 252. The method of claim 230, wherein the one or more methylation sites are all of the methylation sites of Table 7.
  • 253. The method of claim 230, wherein the one or more methylation sites are one or more methylation sites of Table 15.
  • 254. The method of claim 230, wherein the one or more methylation sites are 2 or more methylation sites of Table 15.
  • 255. The method of claim 230, wherein the one or more methylation sites are 3 or more methylation sites of Table 15.
  • 256. The method of claim 230, wherein the one or more methylation sites are 4 or more methylation sites of Table 15.
  • 257. The method of claim 230, wherein the one or more methylation sites are 5 or more methylation sites of Table 15.
  • 258. The method of claim 230, wherein the one or more methylation sites are 10 or more methylation sites of Table 15.
  • 259. The method of claim 230, wherein the one or more methylation sites are all of the methylation sites of Table 15.
  • 260. The method of claim 230, wherein the one or more methylation sites are one or more methylation sites of Table 20.
  • 261. The method of claim 230, wherein the one or more methylation sites are 2 or more methylation sites of Table 20.
  • 262. The method of claim 230, wherein the one or more methylation sites are 3 or more methylation sites of Table 20.
  • 263. The method of claim 230, wherein the one or more methylation sites are 4 or more methylation sites of Table 20.
  • 264. The method of claim 230, wherein the one or more methylation sites are 5 or more methylation sites of Table 20.
  • 265. The method of claim 230, wherein the one or more methylation sites are 10 or more methylation sites of Table 20.
  • 266. The method of claim 230, wherein the one or more methylation sites are all of the methylation sites of Table 20.
  • 267. The method of claim 230, wherein the one or more methylation sites are one or more methylation sites of Table 27.
  • 268. The method of claim 230, wherein the one or more methylation sites are 2 or more methylation sites of Table 27.
  • 269. The method of claim 230, wherein the one or more methylation sites are 3 or more methylation sites of Table 27.
  • 270. The method of claim 230, wherein the one or more methylation sites are 4 or more methylation sites of Table 27.
  • 271. The method of claim 230, wherein the one or more methylation sites are 50 or more methylation sites of Table 27.
  • 272. The method of claim 230, wherein the one or more methylation sites are 10 or more methylation sites of Table 27.
  • 273. The method of claim 230, wherein the one or more methylation sites are all of the methylation sites of Table 27.
  • 274. The method of any of claims 230-273, further comprising administering to the subject a therapeutically effective amount of a BCL2 inhibitor.
  • 275. The method of claim 274, wherein the BCL2 inhibitor is ABT-737 or navitoclax.
  • 276. The method of any of claims 230-274, further comprising administering to the subject a therapeutically effective amount of a DLL3-targeted therapeutic.
  • 277. The method of claim 276, wherein the DLL3-targeted therapeutic comprises an anti-DLL3 antibody or fragment thereof.
  • 278. The method of claim 277, wherein the anti-DLL3 antibody or fragment thereof is rovalpituzumab.
  • 279. The method of claim 276, wherein the DLL3-targeted therapeutic is an antibody-drug conjugate.
  • 280. The method of claim 279, wherein the antibody-drug conjugate is rovalpituzumab tesirine.
  • 281. The method of claim 229, wherein (b) comprises classifying the subject as having SCLC-N.
  • 282. The method of claim 281, wherein the one or more methylation sites are one or more methylation sites selected from the methyation sites of Table 3, Table 8, Table 16, Table 21, and Table 28.
  • 283. The method of claim 281, wherein the one or more methylation sites are 2 or more methylation sites selected from the methyation sites of Table 3, Table 8, Table 16, Table 21, and Table 28.
  • 284. The method of claim 281, wherein the one or more methylation sites are 3 or more methylation sites selected from the methyation sites of Table 3, Table 8, Table 16, Table 21, and Table 28.
  • 285. The method of claim 281, wherein the one or more methylation sites are 4 or more methylation sites selected from the methyation sites of Table 3, Table 8, Table 16, Table 21, and Table 28.
  • 286. The method of claim 281, wherein the one or more methylation sites are 5 or more methylation sites selected from the methyation sites of Table 3, Table 8, Table 16, Table 21, and Table 28.
  • 287. The method of claim 281, wherein the one or more methylation sites are 10 or more methylation sites selected from the methyation sites of Table 3, Table 8, Table 16, Table 21, and Table 28.
  • 288. The method of claim 281, wherein the one or more methylation sites are twenty or more methylation sites selected from the methyation sites of Table 3, Table 8, Table 16, Table 21, and Table 28.
  • 289. The method of claim 281, wherein the one or more methylation sites are fifty or more methylation sites selected from the methyation sites of Table 3, Table 8, Table 16, Table 21, and Table 28.
  • 290. The method of claim 281, wherein the one or more methylation sites are one or more methylation sites of Table 3.
  • 291. The method of claim 281, wherein the one or more methylation sites are 2 or more methylation sites of Table 3.
  • 292. The method of claim 281, wherein the one or more methylation sites are 3 or more methylation sites of Table 3.
  • 293. The method of claim 281, wherein the one or more methylation sites are 4 or more methylation sites of Table 3.
  • 294. The method of claim 281, wherein the one or more methylation sites are 5 or more methylation sites of Table 3.
  • 295. The method of claim 281, wherein the one or more methylation sites are 10 or more methylation sites of Table 3.
  • 296. The method of claim 281, wherein the one or more methylation sites are all of the methylation sites of Table 3.
  • 297. The method of claim 281, wherein the one or more methylation sites are one or more methylation sites of Table 8.
  • 298. The method of claim 281, wherein the one or more methylation sites are 2 or more methylation sites of Table 8.
  • 299. The method of claim 281, wherein the one or more methylation sites are 3 or more methylation sites of Table 8.
  • 300. The method of claim 281, wherein the one or more methylation sites are 4 or more methylation sites of Table 8.
  • 301. The method of claim 281, wherein the one or more methylation sites are 5 or more methylation sites of Table 8.
  • 302. The method of claim 281, wherein the one or more methylation sites are 10 or more methylation sites of Table 8.
  • 303. The method of claim 281, wherein the one or more methylation sites are all of the methylation sites of Table 8.
  • 304. The method of claim 281, wherein the one or more methylation sites are one or more methylation sites of Table 16.
  • 305. The method of claim 281, wherein the one or more methylation sites are 2 or more methylation sites of Table 16.
  • 306. The method of claim 281, wherein the one or more methylation sites are 3 or more methylation sites of Table 16.
  • 307. The method of claim 281, wherein the one or more methylation sites are 4 or more methylation sites of Table 16.
  • 308. The method of claim 281, wherein the one or more methylation sites are 5 or more methylation sites of Table 16.
  • 309. The method of claim 281, wherein the one or more methylation sites are 10 or more methylation sites of Table 16.
  • 310. The method of claim 281, wherein the one or more methylation sites are all of the methylation sites of Table 16.
  • 311. The method of claim 281, wherein the one or more methylation sites are one or more methylation sites of Table 21.
  • 312. The method of claim 281, wherein the one or more methylation sites are 2 or more methylation sites of Table 21.
  • 313. The method of claim 281, wherein the one or more methylation sites are 3 or more methylation sites of Table 21.
  • 314. The method of claim 281, wherein the one or more methylation sites are 4 or more methylation sites of Table 21.
  • 315. The method of claim 281, wherein the one or more methylation sites are 5 or more methylation sites of Table 21.
  • 316. The method of claim 281, wherein the one or more methylation sites are 10 or more methylation sites of Table 21.
  • 317. The method of claim 281, wherein the one or more methylation sites are all of the methylation sites of Table 21.
  • 318. The method of claim 281, wherein the one or more methylation sites are one or more methylation sites of Table 28.
  • 319. The method of claim 281, wherein the one or more methylation sites are 2 or more methylation sites of Table 28.
  • 320. The method of claim 281, wherein the one or more methylation sites are 3 or more methylation sites of Table 28.
  • 321. The method of claim 281, wherein the one or more methylation sites are 4 or more methylation sites of Table 28.
  • 322. The method of claim 281, wherein the one or more methylation sites are 5 or more methylation sites of Table 28.
  • 323. The method of claim 281, wherein the one or more methylation sites are 10 or more methylation sites of Table 28.
  • 324. The method of claim 281, wherein the one or more methylation sites are all of the methylation sites of Table 28.
  • 325. The method of claim 281-324, further comprising administering to the subject a therapeutically effective amount of an AURK inhibitor.
  • 326. The method of claim 325, wherein the AURK inhibitor is CYC-116, alisertib, or AS-703569.
  • 327. The method of claim 229, wherein (b) comprises classifying the subject as having SCLC-P.
  • 328. The method of claim 327, wherein the one or more methylation sites are one or more methylation sites selected from the methyation sites of Table 4, Table 9, Table 17, Table 22, and Table 29.
  • 329. The method of claim 327, wherein the one or more methylation sites are 2 or more methylation sites selected from the methyation sites of Table 4, Table 9, Table 17, Table 22, and Table 29.
  • 330. The method of claim 327, wherein the one or more methylation sites are 3 or more methylation sites selected from the methyation sites of Table 4, Table 9, Table 17, Table 22, and Table 29.
  • 331. The method of claim 327, wherein the one or more methylation sites are 4 or more methylation sites selected from the methyation sites of Table 4, Table 9, Table 17, Table 22, and Table 29.
  • 332. The method of claim 327, wherein the one or more methylation sites are 5 or more methylation sites selected from the methyation sites of Table 4, Table 9, Table 17, Table 22, and Table 29.
  • 333. The method of claim 327, wherein the one or more methylation sites are 10 or more methylation sites selected from the methyation sites of Table 4, Table 9, Table 17, Table 22, and Table 29.
  • 334. The method of claim 327, wherein the one or more methylation sites are twenty or more methylation sites selected from the methyation sites of Table 4, Table 9, Table 17, Table 22, and Table 29.
  • 335. The method of claim 327, wherein the one or more methylation sites are fifty or more methylation sites selected from the methyation sites of Table 4, Table 9, Table 17, Table 22, and Table 29.
  • 336. The method of claim 327, wherein the one or more methylation sites are one or more methylation sites of Table 4.
  • 337. The method of claim 327, wherein the one or more methylation sites are 2 or more methylation sites of Table 4.
  • 338. The method of claim 327, wherein the one or more methylation sites are three or more methylation sites of Table 4.
  • 339. The method of claim 327, wherein the one or more methylation sites are 4 or more methylation sites of Table 4.
  • 340. The method of claim 327, wherein the one or more methylation sites are 5 or more methylation sites of Table 4.
  • 341. The method of claim 327, wherein the one or more methylation sites are 10 or more methylation sites of Table 4.
  • 342. The method of claim 327, wherein the one or more methylation sites are all of the methylation sites of Table 4.
  • 343. The method of claim 327, wherein the one or more methylation sites are one or more methylation sites of Table 9.
  • 344. The method of claim 327, wherein the one or more methylation sites are 2 or more methylation sites of Table 9.
  • 345. The method of claim 327, wherein the one or more methylation sites are 3 or more methylation sites of Table 9.
  • 346. The method of claim 327, wherein the one or more methylation sites are 4 or more methylation sites of Table 9.
  • 347. The method of claim 327, wherein the one or more methylation sites are 5 or more methylation sites of Table 9.
  • 348. The method of claim 327, wherein the one or more methylation sites are 10 or more methylation sites of Table 9.
  • 349. The method of claim 327, wherein the one or more methylation sites are all of the methylation sites of Table 9.
  • 350. The method of claim 327, wherein the one or more methylation sites are one or more methylation sites of Table 17.
  • 351. The method of claim 327, wherein the one or more methylation sites are 2 or more methylation sites of Table 17.
  • 352. The method of claim 327, wherein the one or more methylation sites are 3 or more methylation sites of Table 17.
  • 353. The method of claim 327, wherein the one or more methylation sites are 4 or more methylation sites of Table 17.
  • 354. The method of claim 327, wherein the one or more methylation sites are 5 or more methylation sites of Table 17.
  • 355. The method of claim 327, wherein the one or more methylation sites are 10 or more methylation sites of Table 17.
  • 356. The method of claim 327, wherein the one or more methylation sites are all of the methylation sites of Table 17.
  • 357. The method of claim 327, wherein the one or more methylation sites are one or more methylation sites of Table 22.
  • 358. The method of claim 327, wherein the one or more methylation sites are 2 or more methylation sites of Table 22.
  • 359. The method of claim 327, wherein the one or more methylation sites are 3 or more methylation sites of Table 22.
  • 360. The method of claim 327, wherein the one or more methylation sites are 4 or more methylation sites of Table 22.
  • 361. The method of claim 327, wherein the one or more methylation sites are 5 or more methylation sites of Table 22.
  • 362. The method of claim 327, wherein the one or more methylation sites are 10 or more methylation sites of Table 22.
  • 363. The method of claim 327, wherein the one or more methylation sites are all of the methylation sites of Table 22.
  • 364. The method of claim 327, wherein the one or more methylation sites are one or more methylation sites of Table 29.
  • 365. The method of claim 327, wherein the one or more methylation sites are 2 or more methylation sites of Table 29.
  • 366. The method of claim 327, wherein the one or more methylation sites are 3 or more methylation sites of Table 29.
  • 367. The method of claim 327, wherein the one or more methylation sites are 4 or more methylation sites of Table 29.
  • 368. The method of claim 327, wherein the one or more methylation sites are 5 or more methylation sites of Table 29.
  • 369. The method of claim 327, wherein the one or more methylation sites are 10 or more methylation sites of Table 29.
  • 370. The method of claim 327, wherein the one or more methylation sites are all of the methylation sites of Table 29.
  • 371. The method of any of claims 327-370, further comprising administering to the subject a therapeutically effective amount of a platinum-containing chemotherapeutic agent.
  • 372. The method of claim 371, wherein the platinum-containing chemotherapeutic agent is cisplatin, carboplatin, oxaliplatin, nedaplatin, picoplatin, or satraplatin.
  • 373. The method of any of claims 327-349, further comprising administering to the subject a therapeutically effective amount of a PARP inhibitor.
  • 374. The method of claim 373, wherein the PARP inhibitor is talazoparib, olaparib, niraparib, AZD-2461, or rucaparib.
  • 375. The method of any of claims 327-349, further comprising administering to the subject a therapeutically effective amount of an anti-metabolite.
  • 376. The method of claim 375, wherein the anti-metabolite is pemetrexed, methotrexate, or pralatrexate.
  • 377. The method of any of claims 327-349, further comprising administering to the subject a therapeutically effective amount of a nucleoside analog.
  • 378. The method of claim 377, wherein the nucleoside analog is floxuridine, cytarabine, clofarabine, or fludarabine.
  • 379. The method of claim 229, wherein (b) comprises classifying the subject as having SCLC-I.
  • 380. The method of claim 379, wherein the one or more methylation sites are one or more methylation sites selected from the methyation sites of Table 5, Table 10, Table 18, Table 23, and Table 30.
  • 381. The method of claim 379, wherein the one or more methylation sites are 2 or more methylation sites selected from the methyation sites of Table 5, Table 10, Table 18, Table 23, and Table 30.
  • 382. The method of claim 379, wherein the one or more methylation sites are 3 or more methylation sites selected from the methyation sites of Table 5, Table 10, Table 18, Table 23, and Table 30.
  • 383. The method of claim 379, wherein the one or more methylation sites are 4 or more methylation sites selected from the methyation sites of Table 5, Table 10, Table 18, Table 23, and Table 30.
  • 384. The method of claim 379, wherein the one or more methylation sites are 5 or more methylation sites selected from the methyation sites of Table 5, Table 10, Table 18, Table 23, and Table 30.
  • 385. The method of claim 379, wherein the one or more methylation sites are 10 or more methylation sites selected from the methyation sites of Table 5, Table 10, Table 18, Table 23, and Table 30.
  • 386. The method of claim 379, wherein the one or more methylation sites are twenty or more methylation sites selected from the methyation sites of Table 5, Table 10, Table 18, Table 23, and Table 30.
  • 387. The method of claim 379, wherein the one or more methylation sites are fifty or more methylation sites selected from the methyation sites of Table 5, Table 10, Table 18, Table 23, and Table 30.
  • 388. The method of claim 379, wherein the one or more methylation sites are one or more methylation sites of Table 5.
  • 389. The method of claim 379, wherein the one or more methylation sites are 2 or more methylation sites of Table 5.
  • 390. The method of claim 379, wherein the one or more methylation sites are 3 or more methylation sites of Table 5.
  • 391. The method of claim 379, wherein the one or more methylation sites are 4 or more methylation sites of Table 5.
  • 392. The method of claim 379, wherein the one or more methylation sites are 5 or more methylation sites of Table 5.
  • 393. The method of claim 379, wherein the one or more methylation sites are 10 or more methylation sites of Table 5.
  • 394. The method of claim 379, wherein the one or more methylation sites are all of the methylation sites of Table 5.
  • 395. The method of claim 379, wherein the one or more methylation sites are one or more methylation sites of Table 10.
  • 396. The method of claim 379, wherein the one or more methylation sites are 2 or more methylation sites of Table 10.
  • 397. The method of claim 379, wherein the one or more methylation sites are 3 or more methylation sites of Table 10.
  • 398. The method of claim 379, wherein the one or more methylation sites are 4 or more methylation sites of Table 10.
  • 399. The method of claim 379, wherein the one or more methylation sites are 5 or more methylation sites of Table 10.
  • 400. The method of claim 379, wherein the one or more methylation sites are 10 or more methylation sites of Table 10.
  • 401. The method of claim 379, wherein the one or more methylation sites are all of the methylation sites of Table 10.
  • 402. The method of claim 379, wherein the one or more methylation sites are one or more methylation sites of Table 18.
  • 403. The method of claim 379, wherein the one or more methylation sites are 2 or more methylation sites of Table 18.
  • 404. The method of claim 379, wherein the one or more methylation sites are 3 or more methylation sites of Table 18.
  • 405. The method of claim 379, wherein the one or more methylation sites are 4 or more methylation sites of Table 18.
  • 406. The method of claim 379, wherein the one or more methylation sites are 5 or more methylation sites of Table 18.
  • 407. The method of claim 379, wherein the one or more methylation sites are 10 or more methylation sites of Table 18.
  • 408. The method of claim 379, wherein the one or more methylation sites are all of the methylation sites of Table 18.
  • 409. The method of claim 379, wherein the one or more methylation sites are one or more methylation sites of Table 23.
  • 410. The method of claim 379, wherein the one or more methylation sites are 2 or more methylation sites of Table 23.
  • 411. The method of claim 379, wherein the one or more methylation sites are 3 or more methylation sites of Table 23.
  • 412. The method of claim 379, wherein the one or more methylation sites are 4 or more methylation sites of Table 23.
  • 413. The method of claim 379, wherein the one or more methylation sites are 5 or more methylation sites of Table 23.
  • 414. The method of claim 379, wherein the one or more methylation sites are 10 or more methylation sites of Table 23.
  • 415. The method of claim 379, wherein the one or more methylation sites are all of the methylation sites of Table 23.
  • 416. The method of claim 379, wherein the one or more methylation sites are one or more methylation sites of Table 30.
  • 417. The method of claim 379, wherein the one or more methylation sites are 2 or more methylation sites of Table 30.
  • 418. The method of claim 379, wherein the one or more methylation sites are 3 or more methylation sites of Table 30.
  • 419. The method of claim 379, wherein the one or more methylation sites are 4 or more methylation sites of Table 30.
  • 420. The method of claim 379, wherein the one or more methylation sites are 5 or more methylation sites of Table 30.
  • 421. The method of claim 379, wherein the one or more methylation sites are 10 or more methylation sites of Table 30.
  • 422. The method of claim 379, wherein the one or more methylation sites are all of the methylation sites of Table 30.
  • 423. The method of any of claims 379-422, further comprising administering to the subject a therapeutically effective amount of an immunotherapy.
  • 424. The method of claim 423, wherein the immunotherapy is a checkpoint blockade therapy.
  • 425. The method of any of claims 379-401, further comprising administering to the subject a therapeutically effective amount of a BTK inhibitor.
  • 426. The method of claim 425, wherein the BTK inhibitor is ibrutinib.
  • 427. The method of any of claims 229-426, wherein the DNA is obtained from blood or plasma from the subject.
  • 428. The method of any of claims 229-427, wherein the DNA is circulating tumor DNA (ctDNA).
  • 429. The method of any of claims 229-426, wherein the DNA is obtained from cancer tissue from the subject.
  • 430. The method of any of claims 229-429, further comprising determining, from the DNA from the subject, a methylation status of one or more methylation sites of Table 13.
  • 431. The method of claim 430, wherein the one or more methylation sites are one or more methylation sites of Table 13.
  • 432. The method of claim 430, wherein the one or more methylation sites are 5 or more methylation sites of Table 13.
  • 433. A method of identifying a subject with cancer as having SCLC, the method comprising: (a) determining, from DNA from the subject, a methylation status of one or more methylation sites of Table 13; and(b) identifying the subject as having SCLC based on the methylation status of the one or more methylation sites.
  • 434. The method of claim 433, wherein the one or more methylation sites are 2 or more methylation sites of Table 13.
  • 435. The method of claim 433, wherein the one or more methylation sites are 5 or more methylation sites of Table 13.
  • 436. The method of claim 433, wherein the one or more methylation sites are 10 or more methylation sites of Table 13.
  • 437. The method of claim 433, wherein the one or more methylation sites are twenty or more methylation sites of Table 13.
  • 438. The method of claim 433, wherein the one or more methylation sites are all of the methylation sites of Table 13.
  • 439. The method of any of claims 433-438, wherein the DNA is obtained from blood or plasma from the subject.
  • 440. The method of any of claims 433-439, wherein the DNA is ctDNA.
  • 441. The method of any of claims 433-438, wherein the DNA is obtained from cancer tissue from the subject.
  • 442. The method of any of claims 433-441, further comprising treating the subject for SCLC.
  • 443. A method for treating a subject for SCLC comprising administering an SCLC therapy to a subject determined, from analysis of tumor DNA from the subject, to have differential methylation at one or more methylation sites of Table 13 compared to a reference or control sample.
  • 444. The method of claim 443, wherein the SCLC therapy comprises chemotherapy, immunotherapy, radiotherapy, or a combination thereof.
  • 445. The method of claim 443 or 444, wherein the SCLC therapy comprises a platinum-containing chemotherapeutic agent.
  • 446. The method of claim 445, wherein the platinum-containing chemotherapeutic agent is cisplatin, carboplatin, oxaliplatin, nedaplatin, picoplatin, or satraplatin.
  • 447. The method of any of claims 443-446, wherein the one or more methylation sites are 2 or more methylation sites of Table 13.
  • 448. The method of any of claims 443-446, wherein the one or more methylation sites are 5 or more methylation sites of Table 13.
  • 449. A method of evaluating tumor burden in a subject having SCLC, the method comprising determining, from DNA from the subject, a methylation status of one or more methylation sites of Table 24.
  • 450. The method of claim 449, wherein the one or more methylation sites are 2 or more methylation sites of Table 24.
  • 451. The method of claim 449, wherein the one or more methylation sites are 3 or more methylation sites of Table 24.
  • 452. The method of claim 449, wherein the one or more methylation sites are 4 or more methylation sites of Table 24.
  • 453. The method of claim 449, wherein the one or more methylation sites are 5 or more methylation sites of Table 24.
  • 454. The method of claim 449, wherein the one or more methylation sites are 10 or more methylation sites of Table 24.
  • 455. The method of claim 449, wherein the one or more methylation sites are twenty or more methylation sites of Table 24.
  • 456. The method of claim 449, wherein the one or more methylation sites are all of the methylation sites of Table 24.
  • 457. The method of any of claims 449-456, wherein the DNA is obtained from blood or plasma from the subject.
  • 458. The method of any of claims 449-456, wherein the DNA is ctDNA.
  • 459. The method of any of claims 449-456, wherein the DNA is obtained from cancer tissue from the subject.
  • 460. A method for determining a response of a subject having SCLC to a cancer therapy, the method comprising determining, from DNA from the subject, a methylation status of one or more methylation sites of Table 24.
  • 461. The method of claim 460, wherein the one or more methylation sites are 2 or more methylation sites of Table 24.
  • 462. The method of claim 460, wherein the one or more methylation sites are 3 or more methylation sites of Table 24.
  • 463. The method of claim 460, wherein the one or more methylation sites are 5 or more methylation sites of Table 24.
  • 464. The method of claim 460, wherein the one or more methylation sites are 10 or more methylation sites of Table 24.
  • 465. The method of claim 460, wherein the one or more methylation sites are twenty or more methylation sites of Table 24.
  • 466. The method of claim 460, wherein the one or more methylation sites are all of the methylation sites of Table 24.
  • 467. The method of any of claims 460-466, wherein the DNA is obtained from blood or plasma from the subject.
  • 468. The method of any of claims 460-466, wherein the DNA is ctDNA.
  • 469. The method of any of claims 460-466, wherein the DNA is obtained from cancer tissue from the subject.
  • 470. A method for treating a subject having SCLC, the method comprising: (a) determining, from DNA from the subject, a methylation level of one or more methylation sites of Table 24;(b) administering a dose of a first cancer therapy to the subject;(c) determining, from DNA from the subject, an additional methylation level of the one or more methylation sites of Table 24; andif the additional methylation level is not increased compared with the methylation level, administering an additional dose of the first cancer therapy to the subject: orif the additional methylation level is increased compared with the methylation level, administering to the subject a second cancer therapy that is different from the first cancer therapy.
  • 471. The method of claim 470, wherein the one or more methylation sites are 2 or more methylation sites of Table 24.
  • 472. The method of claim 470, wherein the one or more methylation sites are 3 or more methylation sites of Table 24.
  • 473. The method of claim 470, wherein the one or more methylation sites are 5 or more methylation sites of Table 24.
  • 474. The method of claim 470, wherein the one or more methylation sites are 10 or more methylation sites of Table 24.
  • 475. The method of claim 470, wherein the one or more methylation sites are twenty or more methylation sites of Table 24.
  • 476. The method of claim 470, wherein the one or more methylation sites are all of the methylation sites of Table 24.
  • 477. The method of any of claims 470-476, wherein the DNA is obtained from blood or plasma from the subject.
  • 478. The method of any of claims 470-476, wherein the DNA is ctDNA.
  • 479. The method of any of claims 470-476, wherein the DNA is obtained from cancer tissue from the subject.
  • 480. The method of any of claims 470-479, wherein the method comprises administering an additional dose of the cancer therapy to the subject if the additional methylation level is reduced compared with the methylation level.
  • 481. The method of claim 480, wherein the method comprises administering the additional dose of the cancer therapy to the subject if the additional methylation level is reduced by at least 10% compared with the methylation level.
  • 482. The method of claim 481, wherein the method comprises administering the additional dose of the cancer therapy to the subject if the additional methylation level is reduced by at least 20% compared with the methylation level.
CROSS-REFERENCE TO RELATED APPLICATIONS

The present application claims the priority benefit of U.S. provisional application No. 63/156,005, filed Mar. 3, 2021, and U.S. provisional application No. 63/276,475, filed Nov. 5, 2021, which applications are incorporated herein by reference in their entirety.

Government Interests

This invention was made with government support under grant numbers CA213273 and CA256780 awarded by the National Institutes of Health. The government has certain rights in the invention.

PCT Information
Filing Document Filing Date Country Kind
PCT/US2022/018797 3/3/2022 WO
Provisional Applications (2)
Number Date Country
63156005 Mar 2021 US
63276475 Nov 2021 US