Claims
- 1. A flow-through microfluidic device comprising a plurality of stencil layers defining:
a plurality of fluidic inputs; a passive microfluidic mixing region in fluid communication with the plurality of fluid inputs; a first fluidic output; a second fluidic output; a first flow path between the plurality of fluidic inputs and the first fluidic output; a second flow path between the plurality of fluidic inputs and the second fluidic output; a diverter for selectively diverting a fluid from the first flow path to the second flow path.
- 2. The microfluidic device of claim 1 wherein the plurality of stencil layers further defines a reaction region in fluid communication with the mixing region.
- 3. The microfluidic device of claim 2 wherein the reaction region includes a composite channel.
- 4. The microfluidic device of claim 2 wherein the reaction region is adapted to perform a synthesis operation selected from the group consisting of: amide bond forming reactions, aromatic substitution reactions, condensation reactions, cycloaddition reactions, polar addition and elimination reactions, heterocycle forming reactions, olefin forming reactions, oxidation reactions, reduction reactions, enzymatic resolutions, asymmetric synthesis and resolution using chiral templates, asymmetric synthesis and resolution using catalysts, combinatorial synthesis of plasmids, combinatorial synthesis of aptimers, combinatorial synthesis of proteins, combinatorial synthesis of peptides, screening of plasmids, screening of aptimers, screening of proteins, screening of peptides, evaluation of enzyme activity, derivatizing proteins, derivatizing carbohydrates, genomic analysis, polymerase chain reactions (PCR), gene expression, enzymatic activity assays, receptor binding assays, and ELISA assays.
- 5. The microfluidic device of claim 1 wherein at least one stencil layer of the plurality of stencil layers is formed with a polymeric material.
- 6. The microfluidic device of claim 1 wherein at least one stencil layer of the plurality of stencil layers is formed with a self-adhesive tape material.
- 7. The microfluidic device of claim 1 wherein the plurality of stencil layers further defines a shutoff valve.
STATEMENT OF RELATED APPLICATION(S)
[0001] This application claims priority to U.S. Provisional Patent Application Serial No. 60/296,882, filed Jun. 7, 2001 and currently pending.
Provisional Applications (1)
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Number |
Date |
Country |
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60296882 |
Jun 2001 |
US |