This application claims priority of German patent application 103 40 721.9, filed Sep. 4, 2003, which is incorporated by reference herein.
The present invention concerns a microscope.
Microscopes of the kind cited above have been known for some time in the existing art. Very generally, in upright and inverted light microscopes, focusing of the specimen is accomplished by way of a corresponding positioning of the specimen relative to the objective, specifically in such a way that a specimen region to be detected is arranged in the focal plane of the objective. This can be achieved on the one hand by the fact that the objective, optionally together with the objective turret receiving the objective, is positioned along the optical axis relative to the specimen. In this case the specimen, for example mounted on a conventional specimen slide, is clamped in a corresponding holder on the microscope stage, this microscope stage then not being moved in the direction of the optical axis of the microscope objective. This type of focusing is usually utilized with inverted light microscopes. On the other hand, the microscope stage can be arranged movably relative to the microscope stand, and positioned in the direction of the optical axis for focusing. In this case the objective does not perform a motion in the direction of its optical axis relative to the microscope stand. The latter type of focusing is usually utilized with upright light microscopes. Focusing with the aid of the microscope stage also exists, for purposes of the present invention, when the microscope stage comprises a mechanism with which a specimen slide performs a positioning relative to the objective with the aid of a linear or pivoting motion controlled by a galvanometer, as is the case, for example, with the assignee's confocal laser scanning microscopes.
In both cases, a focusing of the specimen to be investigated is usually performed by the fact that an operator operates an operating element arranged on the microscope stand, as a result of which either the objective or the microscope stage is positioned, as a function of the operator's operation, relative to the microscope stand in the direction of the optical axis of the objective. The operating element is a rotary knob, but usually two rotary knobs (one rotary knob for fine drive and one rotary knob for coarse drive) which are arranged rotatably about a rotation axis and are directly or indirectly coupled to a shaft. Rotation of the rotary knob by the operator causes rotation of the shaft coupled to the operating element. The rotation of the shaft is in turn transferred, usually in mechanical fashion, into a linear motion of the microscope stage or the objective in the direction of the optical axis.
The operating element is usually arranged laterally at a certain height on one side wall of the microscope stand, usually a few centimeters away from a support surface on which the microscope stands. This arrangement of the operating element is optimized for an average operator's hand size, but it is arranged too low for operators with large hands, and too high for operators with small hands. For users with a hand size deviating from the average hand size, microscope operation is therefore fatiguing over the long term and as a result, not ergonomic in that respect.
It is therefore the object of the present invention to describe and refine a microscope of the kind cited initially with which the aforementioned problems are eliminated. In particular, the arrangement of the operating element is intended to be adaptable to an operator's needs, so that ergonomic microscope operation is additionally possible for operators irrespective of their hand size.
The above object is achieved by a microscope, a microscope stand; a microscope stage; at least one objective that, in a working position, defines an optical axis; a focusing device having at least one operating element that is provided on the microscope stand, wherein the operating element generates a relative motion between the objective and the microscope stage in the direction of the optical axis and the operating element sits on a first shaft of the focusing device and a side wall is defined by the microscope, wherein the focusing device is modifiable in terms of its position within the microscope stand in such a way that the spatial arrangement of the at least one operating element on the side wall of the microscope stand is adjustable.
What has been recognized according to the present invention is that for different operators with different hand sizes, microscope operation can be performed, in particular in ergonomic and efficient fashion over longer periods of time, when the arrangement or position of the operating element on the microscope stand can be modified. A microscope operator with a small hand size thus need not assist himself by, for example, placing alongside the microscope stand a book on which he then rests his hand for operation of the operating element and thereby decreases the distance between the operating element and the support surface on which the microscope stands. With an arrangement of the operating element on the microscope stand that is modifiable according to the present invention, the position of the operating element is individually adaptable to an operator's needs, the very particularly advantageous result being that fatigue of the user's arm or hand when operating the microscope can be largely prevented, at least with regard to focusing.
It is conceivable in principle that the operating element can be capable of being modified relative to the microscope stand in the horizontal and/or vertical direction relative to a support surface on which the microscope is arranged. Specifically when an operator has a short arm length, it may be advantageous to modify the arrangement of the operating element in the horizontal direction in such a way that he “brings the operating element closer” to himself.
Provision is preferably made, however, for the spatial arrangement of the operating element to be modifiable substantially in the vertical direction. A support carriage, with which the operating element is associated and which is movable along a guide provided on the microscope stand, could be provided for that purpose. The guide can be embodied in such a way that the operating element is adjustable on the microscope stand substantially in a direction parallel to the optical axis. In another embodiment, the spatial arrangement of the at least one operating element on at least one side wall of the microscope stand is adjustable substantially in the vertical and horizontal direction by means of a curved elongated hole.
The support carriage and the associated focus device are usually arranged in the interior of the microscope stand and are thus not visible to the operator. Concretely, an “association” of the operating element with the support carriage is to be understood to mean that the operating element is arranged non-modifiably in terms of its spatial arrangement relative to the support carriage. In this case, the spatial arrangement of the operating element with respect to the microscope stand could thus be varied in the vertical direction by way of a displacement of the support carriage or of the focus device.
The guide for the support carriage could comprise a ball guide, in particular a crossed roller guide, or a plain guide, in particular a dovetail guide. The support carriage could in that respect be mounted or guided in a manner comparable to an objective turret or microscope stage, those assemblies also being arranged displaceably in the direction of the optical axis of an objective.
Very generally, the operating element of the focusing device could comprise at least one pushbutton switch with which the objective or the microscope stage can be positioned. This is the case especially for microscope stands of research microscopes, in which motion of the objective or of the microscope stage is accomplished in motor-controlled fashion. The operating elements configured in the form of pushbutton switches are accordingly embodied as transducers for a control device having a corresponding motor. The microscope is then embodied in such a way that the first shaft of the focusing device is equipped with a coding disk that coacts with a sensor element which converts into electrical signals the rotation of the first shaft generated by the operating element. The sensor element is, for example, a light barrier that is immovably connected to the focusing device. At least one motor that effects the relative motion between the objective and microscope stage is provided in the interior of the microscope stand. For the activation thereof, the motor receives the signals generated by the sensor element.
With simple microscope stands in particular, however, the operating element comprises for focusing at least one rotary knob (operating element), mounted rotatably about a rotation axis, with which focusing is implemented in purely mechanical fashion. This type of focusing has become established not only because of its intuitive operation, and is also used in high-priced microscope stands, if applicable in addition to pushbuttons. In a preferred exemplary embodiment, therefore, the operating element is arranged rotatably about a rotation axis. It is preferably coupled to a shaft that is rotatable as a result of the rotation of the operating element. A configuration of this kind is, considered of itself, known from the existing art.
According to a very particularly preferred embodiment, the operating element is associated with a focus device, the focus device and thus also the operating element being arranged pivotably about a pivot axis. The focus device could be arranged on a support carriage that can be moved substantially in the vertical direction. As a result of this, the spatial arrangement of the operating element relative to the microscope stand could be modified by way of an upward or downward motion of the entire support carriage. On the other hand, given a specific position of the operating element associated with the focus device, the operating element could be pivoted about the pivot axis that is provided, so that horizontal and vertical modifications of the arrangement of the operating element relative to the microscope stand can thus be accomplished simultaneously. Preferably, however, provision is made for providing only a pivoting of the operating element about a pivot axis, the pivot axis being arranged on the microscope stand. The arrangement of the pivot axis on the microscope stand, the spacing between the operating element and the pivot axis, and the definition of the pivot angle range, enable a modification of the spatial arrangement of the operating element on the microscope stand in such a way that motions of the operating element relative to the microscope stand that have substantially a vertical and a horizontal directional component are possible. In particularly advantageous fashion, this embodiment can be embodied relatively easily in terms of design, so that the manufacturing costs therefor can be kept low.
For pivotable arrangement of the operating element, a focusing device could be provided which is arranged pivotably about the pivot axis and with which the operating element is associated. The focus device is preferably arranged in the interior of the microscope stand and in a manner not visible to an operator.
In principle, an operator manipulation of the operating element could be transferred mechanically or in another fashion for generation of a relative motion between the microscope stage and the objective. If the operating element comprises only an electrical transducer, an obvious choice is to transfer the signals generated by the transducer in electrical fashion, for example via a flexible cable connection, and to use them to generate a relative motion between the microscope stage and the objective. A rotatably mounted second shaft arranged substantially coaxially with respect to the pivot axis of the focusing device could be provided, in particular, for mechanical transfer of an operator manipulation of the operating element. The shaft could be embodied in such a way that a rotary motion of a shaft of the operating element is transferable to the second shaft, a prerequisite for this approach being that the operating element be rotatable about a rotation axis and be coupled to a shaft that is rotatable by rotation of the operating element.
In the context of a mechanical transfer of the manipulation of the operating element to the focusing device, provision is preferably made for transferring the rotary motion between the shaft of the operating element and the second shaft in positively engaged fashion. This could be effected, in particular, using at least two gears, one gear preferably being arranged nonrotatably on each shaft and the gears being in meshing engagement with one another. Teeth could also be provided on one shaft in at least one region, so that no gear need be provided on that shaft.
In the context of a pivotably mounted focus device, the rotary motion of the second shaft could be transferable in positively engaged fashion to a mechanism that moves the objective or the microscope stage relative to the microscope stand in the direction of the optical axis of the objective. A “positively engaged transfer” is to be understood in particular as the meshing engagement of at least two components configured in complementary fashion to one another. The two components could, for example, comprise two gears or a gear and a toothed rack.
For the case in which only a relative motion of the focus device (and thus of the operating element) with respect to the microscope stand in the vertical direction is accomplished, the rotary motion of a rotation axis of the operating element associated with the support carriage could be transferable in positively engaged fashion to a mechanism. That mechanism then once again moves the objective or the microscope stage relative to the microscope stand in the direction of the optical axis of the objective.
Very generally, at least one further intermediate shaft could be provided that serves for positively engaged transfer of the rotary motion of a shaft of the operating element to a mechanism that moves the objective or the microscope stage relative to the microscope stand in the direction of the optical axis of the objective. Corresponding step-down or step-up conversions of the rotary motion of the shaft of the operating element to the mechanism can thereby be attained, for example by way of a suitable selection of different gear diameters. This enables on the one hand rapid positioning of the objective or of the microscope stage along an entire positioning range, and on the other hand sufficient fine positioning of the objective or the microscope stage, so that a specific specimen region can be focused in controlled fashion and with sufficient resolution in terms of positioning motion.
Concretely, the mechanism for moving the objective or the microscope stage relative to the microscope stand in the direction of the optical axis of the objective could comprise a toothed rack. In this case the toothed rack is in meshing engagement with the second shaft or with a rotation axis of the operating element associated with the support carriage. Since the microscope stage or the microscope objective must be moved, for focusing, in the direction of the optical axis of the microscope objective, and that axis is usually oriented vertically, an obvious choice is also to align the toothed rack with its longitudinal axis vertical, so that the rotary motion of a shaft in meshing engagement with the toothed rack is converted directly into a linear motion in the vertical direction.
Once the operating element has then been arranged by an operator, in operator-specific fashion, in its spatial positions relative to the microscope stand, provision must be made for immobilizing the operating element in a specific position selected by the operator. Means with which the support carriage or the focus device can be immobilized on the microscope stand are provided for that purpose. This immobilization is preferably accomplished nonpositively, for example by wedging a part of the operating element with respect to the microscope stand.
In very particularly preferred fashion, the at least one operating element comprises a coarse drive and/or a fine drive. It is thus possible for a microscope operator to adjust the microscope stage or the objective, in a familiar manner, over a larger displacement range using the coarse drive and/or over a small displacement range using the fine drive. The coarse drive or fine drive can be embodied, in a manner known from the existing art, in motorized or mechanical fashion, a mechanical embodiment preferably being achievable by way of a recirculating ball drive system.
For a motorized embodiment of the focusing device, at least one motor could be provided with which a shaft of the focusing device is rotatable or drivable. A shaft associated with the operating element could preferably be rotated by the motor. The motor could comprise a stepping motor and, if applicable, a step-down gear drive.
In a preferred embodiment, a guide, on which the microscope stage or an objective turret receiving the objective is movable, is provided on the microscope stand. This guide could be a ball guide, in particular a crossed roller guide, or a plain guide, in particular a dovetail guide.
There are various ways of advantageously embodying and refining the teaching of the present invention. In conjunction with the explanation of the preferred exemplary embodiments of the invention with reference to the drawings, an explanation is also given of generally preferred embodiments and refinements of the teaching. In the drawings:
Focusing device 20 encompasses two elongated orifices 25 through which can be introduced a pin or a second shaft (not shown in
The rotary motion of second shaft 21 is transferable in positively engaged fashion to mechanism 24 (see
In
According to the exemplary embodiment of
According to the exemplary embodiment of
In the second exemplary embodiment, opening 15 provided in microscope stand 2 is embodied as a curved elongated hole 13 or as a circle segment, the circle-segment shape being adapted to the distance between pivot axis 21 of focusing device 20 and rotation axis 27 or shaft 26 of operating element 8. The circle-segment-shaped opening 15 of
Number | Date | Country | Kind |
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103 40 721.9 | Sep 2003 | DE | national |