The current disclosure provides a cosmetic solution for body contouring and permanent fat reduction.
An aspect of the current disclosure provides a minimally invasive cosmetic procedure for de-bulking fat comprising steps of: (a) injecting platelet rich plasma (PRP) into a subject area; followed by (b) heating fat cells in the subject area using radiofrequency; followed by (c) aspirating fat cells in the subject area using liposuction; followed by (d) injecting platelet rich plasma (PRP) into the subject area again. In a more detailed embodiment, the PRP injecting step (a) is performed two to seven weeks prior to the heating and liposuction steps (b) and (c); and the PRP injecting step (d) is performed several days to four weeks after the heating and liposuction steps (b) and (c). In an embodiment, the liposuction step (c) uses power-assisted liposuction (PAL). In an embodiment, the heating step (b) uses directional RF technology.
Unlike any prior-art procedure for fat reduction, the current disclosure provides a minimally invasive cosmetic procedure that permanently removes fat cells and regenerates healthy, firmer and younger looking skin. “FirmSculpt” is a unique 3-step protocol that incorporates Radio-Frequency Energy, Platelet Rich Plasma (PRP) and Power Assisted Liposuction. The integration of these technologies delivers dramatic results that cannot be achieved by any single or current combination of technologies available today.
The first step is PRP injections into the treatment area both before and after liposuction. PRP not only regenerates tissue, stimulates collagen production and increases blood flow resulting in less down time as compared to other minimally-invasive liposuction procedures, but also leads to firmer and healthier looking skin. This procedure may be performed anywhere from 4 to 6 weeks (e.g., 30 days) prior to and 4 to 6 weeks after liposuction (e.g., 30 days). Considering the well- known regenerative nature of PRP, by injecting the treatment area prior to liposuction, the fibroblast cells begin to stimulate new collagen. Fibroblasts are the most common cells of connective tissue in humans; and, therefore, by injecting the treatment area with PRP prior to liposuction, the skin will begin to thicken and “firm up” which both maximizes the liposuction results and speeds up the healing process.
The second step of the protocol involves radiofrequency (RF) delivered by the In-Mode BodyTite® machine. Utilizing this revolutionary directional RF technology results in three-dimensional tissue remodeling through fat coagulation and volumetric heating. The primary benefit of this step is skin retraction and tightening which ultimately yields the optimal “firming” that patients have been seeking for decades. As the most common post-operative complaint from liposuction patients are in fact related to “sagging skin” or laxity, by incorporating this leading RF technology patients experience tighter and firmer skin with overall superior results than can be achieved through other fat reduction treatments with or without liposuction alone. After the patient is comfortably anesthetized under awake oral sedation and the tumescent solution with local anesthesia infused (mix of saline, lidocaine and epinephrine), the physician uses RF to safely heat the area and “melt” the fat prior to the liposuction (aspiration).
The third and final step of the procedure is the afore-mentioned Power-Assisted Liposuction (PAL). PAL enables the practitioner to target areas of the body with greater precision than traditional liposuction which again leads to more dramatic results. The practitioner permanently removes the majority of the fat cells using variously sized cannulas to aspirate the fat which is then disposed of properly via strict OSHA guidelines. Patients can often observe their early body contouring with both fat reduction from the liposuction and skin tightening from the RF procedure as the physician is literally sculpting the patient’s body.
In summary, “FirmSculpt” is a totally new concept combining multiple non-invasive technologies with liposuction to create a new multimodal approach to treat in a more permanent manner the long-standing problem of skin laxity after both non-invasive and surgical fat removal which we believe will revolutionize the industry.
Exemplary Proprietary Aspects: Specific proprietary is the pre and post regenerative state health of tissue going through conditioning treatment due to regenerative growth factors and angiogenesis pre and post liposuction. Why this proprietary protocol has not been adapted before is because of the exact steps of the procedure. RF/PRP is known as a sole treatment. Fat grafting/PRP is also known as a sole treatment. But PRP prior to the RF and liposuction then PRP post, has not due to most practitioners either specializing in device procedures such as RF or specializing in cosmetic procedures such as liposuction. Further, it has only been recently known that regenerative procedures in any format have been incorporated into clinic treatments in the US.
Scientific Support: This proprietary procedure protocol works based on the documented science studies of each of the individual treatment steps.
The PRP regenerative process (both prior to and post-liposuction) shows proprietary results in that the treated areas have regenerative tissue and new blood supply to initiate the liposuction and has regenerative and healing properties post liposuction.
This procedure only derives the proprietary results because of the exact protocol steps of PRP, RF, Liposuction, PRP. This is because normally the body sees artificial removal of adipose as unnatural so surrounding tissues post adipose removal do not uniformly regain uniform internal tissue fluid movement of blood flow. So some tissue areas respond better than others.
However, when the dermal areas are treated prior to adipose removal in a regenerative format with PRP and RF the newly acquired angiogenesis of new blood supplies to those areas allows all areas to format uniformly. And this is further assisted with post treatment regenerative PRP which also greatly assists in the uniform healing properties.
Key collaborative studies are listed below. These studies provide the scientific support for our claims. They include studies on PRP promotion of healthier body adipose, proliferation and of PRP regenerative body tissue healing/proliferation.
Lacci KM, Dardik A. Platelet-rich plasma: support for its use in wound healing. Yale J Biol Med. 2010;83(1):1-9.
Xu P, Wu Y, Zhou L, et al. Platelet-rich plasma accelerates skin wound healing by promoting re-epithelialization. Burns Trauma. 2020;8:tkaa028. Published 2020 Aug 14. doi: 10.1093/burnst/tkaa028
Oneto P, Etulain J. PRP in wound healing applications. Platelets. 2021;32(2):189-199. doi:10.1080/09537104.2020.1849605
Badis D, Omar B. The effectiveness of platelet-rich plasma on the skin wound healing process: A comparative experimental study in sheep. Vet World. 2018;11(6):800-808. doi:10.14202/vetworld.2018.800-808
Lacci KM, Dardik A. Platelet-rich plasma: support for its use in wound healing. Yale J Biol Med. 2010;83(1):1-9.
Chicharro-Alcantara D, Rubio-Zaragoza M, Damia-Gimenez E, et al. Platelet Rich Plasma: New Insights for Cutaneous Wound Healing Management. J Funct Biomater. 2018;9(1):10. Published 2018 Jan 18. doi:10.3390/jfb9010010
Li Y, Mou S, Xiao P, et al. Delayed two steps PRP injection strategy for the improvement of fat graft survival with superior angiogenesis. Sci Rep. 2020;10(1):5231. Published 2020 Mar 23. doi:10.1038/s41598-020-61891-6
Serra-Mestre JM, Serra-Renom JM, Martinez L, Almadori A, D’Andrea F. Platelet-rich plasma mixed-fat grafting: a reasonable prosurvival strategy for fat grafts?. Aesthetic Plast Surg. 2014;38(5):1041-1049. doi: 10.1007/s00266-014-0374-7
Modarressi A. Platlet Rich Plasma (PRP) Improves Fat Grafting Outcomes. World J Plast Surg. 2013;2(1):6-13.
Modarressi A. Platlet Rich Plasma (PRP) Improves Fat Grafting Outcomes. World J Plast Surg. 2013;2(1):6-13
Luck J, Smith OJ, Mosahebi A. A Systematic Review of Autologous Platelet-Rich Plasma and Fat Graft Preparation Methods. PlastReconstr Surg Glob Open. 2017;5(12):e1596. Published 2017 Dec 6. doi:10.1097/GOX.0000000000001596
Each of the above-listed articles are incorporated herein by reference.
FirmSculpt is a minimally-invasive, awake-liposuction procedure that combines the radiofrequency and fat emulsion technology of BodyTite® and/or FaceTite® (by InMode®), the regenerative, restorative and rejuvenative properties derived from medical-grade Platelet Rich Plasma (PRP) by DrPRPUSA®, and the advanced technology of a Power-Assisted Liposuction system by HK Surgical.
Below is an exemplary protocol:
The current application claims priority to U.S Provisional Application Serial No. 63/241,336, filed Sep. 7, 2021, the entire disclosure of which is incorporated herein by reference.
Number | Date | Country | |
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63241336 | Sep 2021 | US |