The present disclosure relates generally to devices and methods of mixing. More specifically, the present disclosure relates to devices and methods for mixing fluids, semi-fluids, gels, particles, powders, and other flowable material.
Flowable materials, such as, but not limited, to creams and medicines, are often a mixture of several components. Frequently, the components need to be mixed in a high speed mixer in order to create a homogenous mixer. Typically, the components to be mixed are added to a mixing container which is inserted into mechanical mixer. After mixing the container is removed from the mixer and the contents transferred to an intermediary dispensing device which dispenses a quantity of the contents into a number of containers intended to be provided to patients. A problem with using an intermediary dispensing device is that a small residual portion of the contents of the initial mixing container are not transferred to the dispensing device and are left on the walls or the bottom of the mixing container It would be desirable to have a mixing container that would, after the contents are mixed therein by the mixer, permit controlled dispensing of the contents directly from the container without requiring transfer to an intermediary dispensing device. Such a device would improve the efficiency and thoroughness of the materials transfer.
The following presents a simplified summary in order to provide a basic understanding of some aspects of various invention embodiments. The summary is not an extensive overview of the invention. It is neither intended to identify key or critical elements of the invention nor to delineate the scope of the invention. The following summary merely presents some concepts of the invention in a simplified form as a prelude to the more detailed description below.
In exemplary embodiments, a device is provided for mixing and dispensing a flowable material or mixture of materials, the device comprising a cup, a plunger, a plug, a nozzle, and a lid. In exemplary embodiments, the cup may comprise a generally cylindrical mixing cup comprising a bottom having a protrusion extending downward therefrom, the protrusion having an aperture defined therethrough, a sidewall, a rim, wherein the sidewall has an interior wall surface and an exterior wall surface, a portion of the exterior wall surface having threads associated therewith. In exemplary embodiments, the plunger is generally cylindrically shaped and adapted to snugly fit at least partially within the mixing cup, the plunger comprising a bottom having at least one reinforcing strut. In exemplary embodiments, the port is associated with or formed in the plunger bottom and has a threaded aperture defined therein, at least one air vent hole defined in the port, and, a sidewall with an exterior surface having an upper sealing member portion adapted to engage the mixing cup sidewall, and a lower sealing member portion adapted to engage the mixing cup sidewall. In exemplary embodiments, the plug has an outer cylindrical portion having an exterior wall including threads, an interior wall including threads, and a central plugging member, the plug adapted to removably engage either the mixing cup protrusion or the plunger port. In exemplary embodiments, the nozzle is hollow and has a proximal end having internal threads adapted to engage with the plunger port, has a distal end. In exemplary embodiments, the lid has interior threads adapted to removably engage the cup rim. In exemplary embodiments, the device may also optionally include a cap adapted to removably fit over the distal end of the nozzle.
An apparatus for mixing and dispensing flowable material is provided, comprising a mixer and a cup device as described.
The drawings disclose exemplary embodiments in which like reference characters designate the same or similar parts throughout the figures of which:
Unless otherwise indicated, the drawings are intended to be read (for example, cross-hatching, arrangement of parts, proportion, degree, or the like) together with the specification, and are to be considered a portion of the entire written description of this invention. As used in the following description, the terms “horizontal”, “vertical”, “left”, “right”, “up” and “down”, “upper” and “lower” as well as adjectival and adverbial derivatives thereof (for example, “horizontally”, “upwardly”, or the like), simply refer to the orientation of the illustrated structure as the particular drawing figure faces the reader. Similarly, the terms “inwardly” and “outwardly” generally refer to the orientation of a surface relative to its axis of elongation, or axis of rotation, as appropriate.
Dynamic mixing, such as rotation mixing, can provide effective, non-invasive mixing of flowable materials 10,. Dual asymmetric rotation mixing can be particularly fast and effective by imposing centrifugal forces on the substance(s) to be mixed. Various containers can be selected for containing the material(s) to be mixed and undergoing the dual asymmetric rotation. Materials that can be mixed using the presently disclosed invention include, but are not limited to, fluids, semi-fluids, suspensions, colloids, gels, pastes, articles, granules, powders, other flowable material, and mixtures or combinations of at least two of the foregoing. Examples of materials that can be mixed include, but are not limited to, creams to be mixed and formulated with medicinal material, as well as epoxies, inks, adhesives, sealants, coatings, and the like.
Examples of suitable rotational mixers 12 can be found in U.S. Pat. Nos. 6,099,160 and 6,755,565, the disclosures of each of which are incorporated by reference, including, but not limited to, those portions disclosing devices, systems, and methods for mixing and associated components and accessories. Such dual axis rotation mixing including dual asymmetric rotation may be referred to as planetary mixing and/or centrifugal mixing, although these terms may not be entirely accurate and are not intended to limit mixing parameters such as the direction of rotation about each of the dual axes, speed, and/or other geometry relationships.
In exemplary embodiments, the cup 22 is formed of plastic. In exemplary embodiments, the cup 22 may be made of any generally rigid and inert material that is able to withstand the rotational forces during mixing, for example, polypropylene, polyethylene, polystyrene, polyurethane, tin, aluminum, steel, silicon dioxide, mixtures and combinations of the foregoing, and the like. In exemplary embodiments, the volume of substance within the cup 22 may be within a range of about 0.1 ml to about 20,000 ml, depending on the size of the cup 22 and other components, and the size of the mixer.
In exemplary embodiments, a cup plug 40 as shown in
In exemplary embodiments, the plug 40 can removably be associated with the cup bottom protrusion 30, such as by screwing into the aperture 32 (as show in
As shown in
In exemplary embodiments, the lower sealing member 80 may be a ring-shaped protrusion extending outward from the plunger 60. The lower sealing member 80 may have an angled shape, as shown in
The plunger 60 has an external diameter (including the sealing members 80 and/or 82) similar to internal diameter of the cup 22, so that the plunger 60 slidingly but snugly fits at least partially within the cup 22, with the sealing member(s) 80, 82 making contact with the cup interior wall 28B so as to urge any material 10 clinging to the interior wall downward when the plunger 60 is urged downward in the cup 22 (as described further hereinbelow). In exemplary embodiments, the height of the plunger 60 is less than the height of the cup 22 so that the plunger 60 may fit entirely within the cup 22. In exemplary embodiments, the plunger 60 has one or more air vent holes 84 formed proximate to the port 70 (as shown in
When in use, as further described hereinbelow, the plug 40 may be removably associated with the port 70 so as to seal the air vent holes 84.
In exemplary embodiments, a removable lid 90, as shown in
In exemplary embodiments, a hollow nozzle 100, as shown in
In one exemplary embodiment, device may be assembled and used as follows. A pharmacist, technician, or other operator (or, apparatus, where an automated filler is used) inserts the plug 40 into the cup bottom protrusion 30 (
The cup 22 is then filled with the material 10, such as, but not limited to, a base material and an active ingredient (
The filled cup 22 is then placed in the mixer 12 and the material is mixed. The cup 22 is then removed from the mixer 12.
The cup 22 is readied for dispensing by unscrewing the lid 80 and inserting the plunger 60 into the cup 22, as shown in
The operator than fastens the nozzle 100 to the cup protrusion 30 (
The operator can then replace the lid 90 on the cup 22 (
In one alternative exemplary embodiment of a device 200,
In another exemplary embodiment of a plunger 300, the plunger sealing members, shown in
A benefit of the interior and exterior sets of threads 50, 46 of the plug (in exemplary embodiments) is the plug 40 has a dual use, namely, to plug the cup 22 during mixing, and to plug the plunger 60 during dispensing. An advantage of the plunger port 70 is that it occupies volume in the cup protrusion 30, forcing material 10 into the nozzle 100 to reduce residual undispensed material.
An advantage of the presently described devices is that the same cup 22 can be used for mixing as well as delivering the mixed material 10 to the containers to be filled. This avoids transfer of the mixed material 10 from a mixing cup to a dispensing cup/container. The isolation of the mixed material 10 within the cup 22 and against the plunger 60 also avoids or reduces exposure of the mixed material 10 to air 110.
In one exemplary embodiment, an apparatus for mixing and dispensing a flowable material or mixture of materials is provided, the apparatus comprising a rotation mixer and a mixing cup. The rotation mixer may comprise a housing, a motor, a basket for holding in relative position a mixing cup containing material for mixing under asymmetric rotation, and, rotating means associated with the motor for rotating the basket at high speed so as to mix the material in the mixing cup. A mixing cup device may be according to one or more of the exemplary embodiments described hereinabove. In one exemplary embodiment, the mixing cup device comprises a generally cylindrical mixing cup having a bottom including a protrusion extending downward therefrom, the protrusion having an aperture defined therethrough. The device further includes a plunger comprising a bottom including a central port associated with the plunger bottom and having a threaded aperture defined therein, the plunger further comprising a sidewall having an exterior surface including at least one sealing member adapted to engage the cup. The device further includes a plug adapted to removably engage the cup protrusion and the plunger port. The device further includes a lid adapted to be removably engaged to the cup.
In another exemplary embodiment, an apparatus for mixing and dispensing a flowable material or mixture of materials is provided, the apparatus comprising a rotation mixer and a mixing cup. The rotation mixer may comprise a housing, a motor, a basket for holding in relative position a mixing cup containing material for mixing under asymmetric rotation, and, rotating means associated with the motor for rotating the basket at high speed so as to mix the material in the mixing cup. A mixing cup device comprises a generally cylindrical mixing cup having a first end including an aperture defined therethrough. The device further includes a plunger comprising a surface complimentary to the first end of the mixing cup, the plunger further comprising a sidewall having an exterior surface including at least one sealing member adapted to engage the cup.
In one exemplary embodiment, a method for mixing and dispensing a flowable material is provided, comprising providing a mixing apparatus as described hereinabove, and providing a mixing cup as described hereinabove. The plug is engaged with the mixing cup protrusion. Material to be mixed is added to the mixing cup. The cup is sealed with the lid. The mixing cup and lid is inserted into the basket in the mixer. The mixer is activated and the material in the mixing cup is rotated to mix the material to form a homogenous material mixture. The cup is removed from the mixer. The lid is removed from the mixing cup. The plunger is inserted into the mixing cup. The plug is disengaged from the mixing cup protrusion. The plug is engaged with the plunger port. The plunger is urged into the mixing cup so as to urge material in the cup toward the cup bottom and so as to cause air in the cup to evacuate through the at least one air vent hole. The nozzle is engaged with the cup protrusion. The plunger is urged toward the cup bottom so as to dispense the material mixture through the nozzle.
In another exemplary embodiment, a method for mixing and dispensing a flowable material is provided, comprising providing a mixing apparatus comprising a rotation mixer comprising a housing, a motor, a basket for holding in relative position a mixing cup containing material for mixing under asymmetric rotation, and rotating means associated with the motor for rotating the basket at high speed so as to mix the material in the mixing cup. A mixing cup is provided, comprising a generally cylindrical mixing cup having a first end including an aperture defined therethrough, a plunger comprising a surface complimentary to the first end of the mixing cup, the plunger further comprising a sidewall having an exterior surface including at least one sealing member adapted to engage the cup, and, a nozzle adapted to be removably engaged to the cup aperture. Material to be mixed is added to the mixing cup. The mixing cup and lid is inserted into the basket in the mixer. The mixer is activated and the material in the mixing cup is rotated to mix the material to form a homogenous material mixture. The cup is removed from the mixer. The nozzle is engaged with the cup protrusion. The plunger is urged toward the first end of the cup so as to dispense the material mixture through the nozzle.
Although only a number of exemplary embodiments have been described in detail above, those skilled in the art will readily appreciate that many modifications are possible in the exemplary embodiments without materially departing from the novel teachings and advantages. Accordingly, all such modifications are intended to be included within the scope of this disclosure as defined in the following claims.
While the methods, equipment and systems have been described in connection with specific embodiments, it is not intended that the scope be limited to the particular embodiments set forth, as the embodiments herein are intended in all respects to be exemplary rather than restrictive.
Unless otherwise expressly stated, it is in no way intended that any method set forth herein be construed as requiring that its steps be performed in a specific order. Accordingly, where a method claim does not actually recite an order to be followed by its steps or it is not otherwise specifically stated in the claims or descriptions that the steps are to be limited to a specific order, it is no way intended that an order be inferred, in any respect.
As used in the specification and the appended claims, the singular forms “a,” “an” and “the” include plural referents unless the context clearly dictates otherwise.
“Optional” or “optionally” means that the subsequently described event or circumstance may or may not occur, and that the description includes instances where said event or circumstance occurs and instances where it does not.
Throughout the description and claims of this specification, the word “comprise” and variations of the word, such as “comprising” and “comprises,” means “including but not limited to,” and is not intended to exclude, for example, other additives, components, integers or steps. “Exemplary” means “an example of” and is not intended to convey an indication of a preferred or ideal embodiment. “Such as” is not used in a restrictive sense, but for explanatory purposes.
Disclosed are components that can be used to perform the disclosed methods, equipment and systems. These and other components are disclosed herein, and it is understood that when combinations, subsets, interactions, groups, etc., of these components are disclosed that while specific reference of each various individual and collective combinations and permutation of these may not be explicitly disclosed, each is specifically contemplated and described herein, for all methods, equipment and systems. This applies to all aspects of this application including, but not limited to, steps in disclosed methods. Thus, if there are a variety of additional steps that can be performed it is understood that each of these additional steps can be performed with any specific embodiment or combination of embodiments of the disclosed methods.
It should further be noted that any patents, applications and publications referred to herein are incorporated by reference in their entirety.
This application claims benefit of co-pending U.S. provisional patent application No. 62/687,972, filed Jun. 21, 2018, entitled MIXING CUP WITH EXTRUSION PLUNGER, and commonly assigned to the assignee of the present application, the disclosure of which is incorporated by reference in its entirety herein.
Number | Date | Country | |
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62687972 | Jun 2018 | US |