Claims
- 1. A thulium containing mixture consisting of a matrix material and thulium oxide homogeneously distributed in said matrix material, said mixture being radioactivatable by exposure to neutron radiation.
- 2. A thulium containing mixture according to claim 1, wherein the thulium content in said matrix material is 0.1 to 25 wt % of the matrix material.
- 3. A thulium containing mixture according to claim 1, wherein the thulium content in said matrix material is 3 to 6 wt %.
- 4. A thulium containing mixture according to claim 1, wherein said matrix material consists of bio-compatible plastics usable for medical applications.
- 5. A thulium containing mixture according to claim 1, wherein said matrix material consist of at least one of the group consisting of polyethylene, polyamide, polypropylene, polytetrafluorethylene, polyvinyliden fluoride, teflon, silicone and PMMA including optionally reinforcement fibers.
- 6. A thulium containing mixture according to claim 1, wherein an x-ray contrasting agent is added to said mixture.
- 7. A thulium containing mixture according to claim 1, wherein at least one additional radioactive or radioactivatable compound which has a half-life and radiation type and energy different from that of thulium is added to said mixture.
- 8. The use of a thulium containing mixture consisting of a matrix material and thulium oxide homogeneously distributed in said matrix material, said mixture being radioactivatable by exposure to neutron radiation as a therapeutic medium in humans and animals.
- 9. Stents for use as a endoprostheses for placement in the form of hoses in human and animal body cavities and passages, said stents comprising thulium containing a mixture consisting of a matrix material and thulium oxide homogeneously distributed in said matrix material, said mixture being radioactivatable by exposure to neutron radiation.
- 10. Stents according to claim 9, disposed in a packaging and radioactivated after closing of said packaging.
- 11. A radioactive material including at least one inert compound of the rare earths, which is distributed in a matrix material and has been radioactivated by neutron irradiation.
- 12. A radioactive material according to claim 11, wherein said inert compound of the rare earth is thulium oxide.
- 13. A radioactive material according to claim 11, wherein the content of compounds of the rare earth is between 0.1 and 25%.
- 14. A radioactive material according to claim 11, wherein said matrix material consist of at least one of the group consisting of polyethylene, polyamide, polypropylene, polytetrafluorethylene, polyvinyliden fluoride, teflon, silicon and PMMA including optionally reinforcement fibers.
- 15. A radioactive material according to claim 11, wherein an x-ray contrasting agent is added to said mixture.
- 16. A radioactive material according to claim 11, wherein at least one additional radioactive or radioactivatable compound which has a half-life and radiation type and energy different from that of thulium is added to said mixture.
- 17. A radioactive material according to claim 11, wherein said neutron irradiation is dosed.
- 18. A radioactive material according to claim 17, wherein said neutron irradiation is selected for providing a radioactivity of 80 μCi/Cm2 material surface for destroying eucharyotic cells and preventing their growth.
- 19. A radioactive material according to claim 17, wherein said neutron irradiation is selected for providing a radioactivity of 20000 μCi/cm2 material surface for destroying prokaryotic cells and for preventing their growth.
- 20. The use of a material mixture including a matrix material with thulium oxide homogeneously mixed with said matrix material and being radioactivatable by exposure to neutron radiation, in medical products consisting of the group of implants, endoprotheses, catheters, stents, heart valve components, plugs for eye therapy, and equipment components.
Priority Claims (2)
Number |
Date |
Country |
Kind |
199 53 636.8 |
Nov 1999 |
DE |
|
199 53 637.6 |
Nov 1999 |
DE |
|
Parent Case Info
[0001] This is a Continuation-in-Part application of international application PCT/EP00/10884 filed Nov. 4, 2000 and claiming the priority of German applications 199 53 638.8 and 199 53 637.6 both filed Nov. 11, 1999.
Continuation in Parts (1)
|
Number |
Date |
Country |
Parent |
PCT/EP00/10884 |
Nov 2000 |
US |
Child |
10131504 |
Apr 2002 |
US |