Patent Application
20200115149
The present invention relates to a moisture barrier package. More particularly, the present invention relates to a moisture barrier package for moisture sensitive agrochemicals.
Art essential prerequisite for selecting a packaging for moisture sensitive agrochemicals is to ensure that there is no interaction between the packaging material and the packaged material throughout the shelf life of the product. The conventional formulation types for agrochemicals are wettable powders, water dispersible granules, dusting powders and granules.
Polyethylene is used in agrochemical packaging because of its moisture barrier properties. However, polyethylene alone does not forth a sufficient packaging, for agrochemicals because of its poor mechanical strength.
Biaxially oriented polyester (PET) has been widely used for packaging of aqueous based products. However, Its Water vapour transmission rate is higher than that of polyethylene making it unsuitable for packaging moisture sensitive compounds.
US 2015 0274408, published on 1 Oct. 2015, discloses an agriculturally active product including a volume of material including an agriculturally active ingredient (acephate), and a package having a package centroid, an interior region, and a distant portion positioned farthest away from the package centroid, the interior region having art interior region centroid and containing the volume of material, the interior region centroid being spaced apart from the package centroid, by an offset distance, the distant portion being spaced apart from the package centroid by a farthest distance, a ratio of the offset distance to the farthest distance being greater than 0.10.
PCT Publication No. WO 1992 017392, published on 15 Oct. 1992, discloses a package containing an agrochemical which package comprises a first sheet of non-planar water soluble or water dispersible material and a second sheet of water soluble of water dispersible material superposed on the first sheet and sealed to it by a continuous closed water soluble or water dispersible seal along a continuous region of the superposed sheets. However, this package suffers from poor mechanical strength and often fells the drop test.
U.S. Pat. No. 5,224,501, published on 6 Jul. 1993, discloses a packaging system containing a pesticidal composition. The packaging system comprises a first sheet, of non-planar water soluble or water dispersible material defining a concavity enclosing the pesticidal composition, a second, sheet of water soluble or waiter dispersible material, sealed to the first sheet by a continuous closed water soluble or water dispersible heat seal, and a third sheet between the first and second sheets and sealed thereto by a water soluble or water dispersible seal to divide the package into two compartments.
CA 2 285 202, published on 2 Sep. 1999, discloses a system and method provided for storing an active ingredient such as a pesticide or other type of agricultural chemical in a water soluble package. The active ingredient is incorporated in a storage formulation including a hydrophilic, non-aqueous solvent which is capable of dissolving the active ingredient but not the water soluble package.
Acephate, O, S-dimethyl acetylphosphoraamidothioate, is an insecticide that is vulnerable to environmental moisture or moisture derived from the packaging material. Therefore, moisture resistant packaging of acephate or formulations containing acephate has been a long felt need in the art. The FAO specifications for packing acephate stipulate, that acephate must not contain more than 2 g/kg of water, as measured by MT. 30, CIPAC F, p. 91, The specification further stipulates that typically the water content should be about 1.5 g/kg. It further states that as acephate technical is hygroscopic, care must be taken to package it In moisture-proof containers and store in dry locations.
The present invention provides an effective moisture harrier packaging system for acephate and for acephate containing agrochemical products.
Therefore, an object of the present invention is to provide a moisture barrier packaging system for moisture sensitive agrochemicals.
Another object of the present invention is to provide a package for moisture sensitive agrochemicals that ensures no interaction, between the packaging material and the packaged material throughput the shelf life of the product.
Another, object of the present invention Is to provide a moisture barrier package for acephate on acephate containing agrochemical products.
The present invention described hereinafter meets at least one, and preferably more than one, of the above mentioned objects of the invention.
A packaged moisture sensitive product, said packaged product comprising:
A method of packing a moisture sensitive product, said method comprising:
Surprisingly, the present inventors have now found that the combination of at least one water soluble polymer layer, at least one first thermoplastic layer, at least one metallic layer and at least one second thermoplastic layer provides surprising mechanical strength to a package intended for a moisture sensitive agrochemical product along with providing the requisite moisture resistance to the packaged agrochemical. More surprisingly, it was found that, the increased mechanical strength and the moisture resistance were prejudiced when, any one of the water soluble polymer layer, or any of the thermoplastic layers or the metallic layer was absent from the packaging. It was unexpected that the described layers, in combination, provided surprising benefits to a packaged agrochemical product that was otherwise very sensitive to environmental moisture exposure.
Therefore, in an aspect, the present invention provides a packaged moisture sensitive product, said packaged product comprising:
In another aspect, the present invention also provides a method of packing a moisture sensitive product, said method comprising:
Both of these aspects, may have several embodiments depending on the preferential selection of the water soluble polymer or either of the thermoplastic layers or of the metallic layer. These embodiments, described hereinafter are non-limiting and are only intended to be the exemplary embodiments of the present invention.
Therefore, in an embodiment, the present invention provides a packaged moisture sensitive product, said packaged product comprising:
In another embodiment, the present invention also provides a method of packing a moisture sensitive product, said method comprising:
In another embodiment, the present invention provides a packaged moisture sensitive product, said packaged product comprising:
In a preferred embodiment, the secondary package is a trilaminated layer comprising 12 micron polyethylene terephthalate, followed by another layer of 12 micron polyethylene terephthalate, a B micron aluminium foil/layer, followed, by a 100 micron low density polyethylene layer.
In another embodiment, the present invention also provides 5 method of packing a moisture sensitive product, said method comprising:
In a preferred embodiment, the secondary package is a trilaminated layer comprising 12 micron polyethylene terephthalate, followed by another layer of 12 micron polyethylene terephthalate, a 8 micron aluminium foil/layer, followed, by a 100 micron low density polyethylene layer.
In another embodiment the secondary package is a trilaminated layer comprising 12 micron polyethylene terephthalate, a 20 micron aluminium foil/layer, followed by a 85 micron tow density polyethylene layer.
Thus, in another embodiment, the present invention provides a packaged moisture sensitive, product said packaged product comprising:
In another embodiment, the present invention also provides a method of packing a moisture sensitive product, said method comprising:
In an embodiment, the moisture sensitive agrochemical product is a phosphoramidothioate insecticide selected from the group consisting of acephate, chloramine phosphorus, isocarbophos, isofenphos, isofenphos-methyl, methamidophos, phosglycin and propetamphos.
In another embodiment, the moisture sensitive agrochemical product is acephate or a formulation comprising the same.
In an embodiment, the moisture sensitive agrochemical product is acephate 97% dry flowable formulation.
Thus, a moisture resistant packaging for 10 kg acephate 97% dry flowable formulation was prepared. A description of the preferred embodiments follows hereinafter, which is not to be considered as limiting.
In an embodiment, the water soluble polymer layer is a water soluble pouch made up of polyvinyl alcohol.
In an embodiment, the water soluble pouch is sealed on a plurality of sides, preferably sealed on two or three sides.
In an exemplary embodiment, the water soluble layer is selected with the following specifications, which were selected for packaging a 10 kg sample of acephate 97% DF formulation. These specifications are exemplary and are not to be construed as limiting the present invention.
In an embodiment, the secondary packaging layer is a 4-layer composite layer comprising the following layers:
Printed PET (12μ)//PET (12μ)//Al foil (9μ)//LDPE (100μ)
In an exemplary embodiment, the secondary packaging is selected with the following specifications, which were selected for packaging a 10 kg sample of acephate 97% DF formulation. These specifications are exemplary and are not to be construed as limiting the scope of the invention in any manner.
The process for preparing such composite laminates is not particularly limiting, and these laminates may be prepared as per the conventional processes known in the art. For example, such laminates may be prepared by compression moulding, extrusion coating, extrusion lamination, tandem extrusion lamination, chemical vapour deposition etc. Such processes are commonly known in the art and are used for preparing the multi-layer laminates of the invention.
In an embodiment, a plurality of such secondary packages, each of said secondary packages comprising acephate 97% DF placed inside the primary package, were disposed within a tertiary packing, which comprises printed cartons.
In an embodiment, the printed carton is laminated with BOPP film for additional moisture resistance.
In a preferred, embodiment, the printed carton is laminated with 10μ BOPP film.
In an embodiment, the printed carton is provided with at least one die cut handle provided for easy handling.
In an embodiment, a plurality of such printed cartons are placed within a shipper packaging.
In an embodiment, the moisture sensitive material which are capable of being packed within the packaging method of the present invention includes, but is not limited to, acephate; combination of acephate and buprofezin; and combination of acephate and imidacloprid and compositions comprising the same.
The tri-laminated pouch PET (24μ)//Al foil (9μ)//LDPE (100μ) along with the ID primary packaging layer of PVA was used to pack acephate 97% DF formulation. The package containing acephate 97% DF was then subjected to AHS study at 54° C.
It was thus found that the packaged sample complied with the specifications up to 28 days in AHS study. AHS study is normally conducted for 14 days at an elevated temperature of 54° C., which according to standard guidelines, provides adequate data in certain circumstances to allow the regulatory authorities to make a regulatory finding regarding the stability of the product and the effect of the formulation on the product packaging.
The tri-laminated pouch PET (24μ)//Al foil (9μ)//LDPE (100μ) along with the primary packaging layer of PVA was used to pack Acephate 97% DF formulation available from UPL Ltd. In the comparative sample, the tri-laminate pouch was replaced with a laminate comprising polyethylene/EVOH layer without a metallic layer.
It was found that there was 0.84% reduction in the percentage active ingredient of acephate in the PE/EvOH (Ethylene Vinyl Alcohol) pouch, whereas only about 0.43% degradation in acephate content in the tri-laminated pouch of the invention. The PE/EvOH pouch, without the metallic layer, also led to highly corrosive smell generated in the pouch.
The acephate+imidacloprid formulation lancer Gold®, available from UPL Ltd, was tested for storage stability in a comparative high barrier film pouch made of 100 micron low density polyethylene. Thus, the test package wad absent of the water soluble polymeric pouch, the thermoplastic layer and the metallized layer. The storage stability of the formulation was tested after AHS storage i.e. after 28 days at 54° C.
Thus, it was found that in the absence of the secondary package and the water soluble polymer of the present invention, acephate content of Lancer Gold® degraded by 2.90% after 28 days, and the imidacloprid content degraded by 33.5% when packed in high barrier film pouch of 100 micron LDPE. A highly corrosive smell was also generated in the pouch. A packaging method and the packaged product according to the present invention was required to pack acephate or acephate containing formulation.
While the foregoing written description of the invention enables one of ordinary skill to make and use what is considered, presently to be the beat mode thereof, those of ordinary skill will understand and appreciate the existence of variations, combinations, end equivalents of the specific embodiment, method, and examples herein. The invention should therefore not be limited by the above described embodiment, method, and examples, but by all embodiments and methods within the scope and spirit of the invention.
| Number | Date | Country | Kind |
|---|---|---|---|
| 201631043367 | Dec 2016 | IN | national |
| Filing Document | Filing Date | Country | Kind |
|---|---|---|---|
| PCT/IB2017/058044 | 12/18/2017 | WO | 00 |
