Claims
- 1. A therapeutic tablet comprising 50 ng to 1,200 mg of morphine; 5 mg to 750 mg of a poly(alkylene oxide) having a 100,000 to 650,000 molecular weight; 0.5 mg to 80 mg of a poly(vinyl pyrrolidone) having a 3,000 to 350,000 molecular weight; and 0 to 7.5 mg of a lubricant, which tablet is encased by a composition comprising a member selected from the group consisting of a cellulose acylate, cellulose diacylate, and cellulose triacylate.
- 2. The therapeutic tablet comprising morphine according to claim 1, wherein the morphine is a member selected from the group consisting of morphine hydrobromide, morphine hydrochloride, morphine mucate, morphine methylbromide, morphine oleate, morphine n-oxide, morphine sulfate, morphine acetate, morphine phosphate monobasic, morphine acetate trihydrate, morphine bi(heptafluorobutyrate), morphine bi(methylcarbamate), morphine bi(pentafluoropropionate), morphine bi(pyridine 3-carboxylate), morphine bi(trifluoroacetate), morphine bitartrate, morphine chlorohydrate, morphine sulfate pentahydrate, and morphine base.
- 3. The therapeutic tablet comprising morphine according to claim 1, wherein the therapeutic tablet is compressed under 1/2 to 25 ton-force of compression.
- 4. A method for administering 50 ng to 1,200 mg of morphine to a human, said method comprising orally administering the morphine to the human from a tablet comprising 50 ng to 1,200 mg of morphine, 5 mg to 750 mg of a poly(alkylene oxide) possessing a 100,000 to 650,000 molecular weight, and 0.5 mg to 80 mg of poly(vinyl pyrrolidone), which tablet is encased by a composition comprising a member selected from the group consisting of a cellulose acylate, cellulose diacylate, and cellulose triacylate comprising an exit passageway.
Parent Case Info
This application is a division of application Ser. No. 08/266,075, filed Jun. 27, 1994, now U.S. Pat. No. 5,460,826 and benefit of the filing date of said earlier filed application is claimed under 35 U.S.C. .sctn. 120.
US Referenced Citations (14)
Foreign Referenced Citations (2)
Number |
Date |
Country |
0377518 |
Jun 1989 |
EPX |
2140687 |
Dec 1984 |
GBX |
Divisions (1)
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Number |
Date |
Country |
Parent |
266075 |
Jun 1994 |
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