The invention relates to an ultra-high frequency multi-element parallel transceive RF coil for use in a magnetic resonance imaging (MRI) system. In particular, the invention relates to a coil structure where the radiating elements of a multi-channel transceive MRI RF coil are optimally oriented to an angle relative to the imaging space to increase the penetration depth of RF fields and to reduce mutual coupling effect so that coil elements can be substantially decoupled. Compared with conventional phased array systems, the new layout of the coil can offer superior RF performance for strongly physically constrained situations, such as dense array RF systems for high-field animal and human MRI. The invention is well suited but not limited to multi-channel, parallel transceive RF coils.
Field/tissue interactions become pronounced at ultra-high field MRI, causing increased RF inhomogeneity. The magnitudes of the inhomogeneity worsen if the dimensions of the sample coincide with the operating wavelength of the radio frequency fields. However, the advantages of being able to gain improved signal-to-noise ratio (SNR) and spectral resolution nevertheless favour the move towards high field MRI. Hence, to benefit from these advantages, the RF inhomogeneity should be ameliorated. A particular method, active RF shimming, which uses spatially selective pulses [Saekho et al, Magn Reson Med 53(2) pg 479-484, 2005] has been shown to yield significant improvement but there are issues associated with this method, explicitly the use of long duration pulses. This, however, can be circumvented through the use of parallel transmission techniques such as Transmit SENSE [Katscher et al, Magn Reson Med 49(1) pg 144-150, 2003], which require dedicated multi-element RF coils and independently controlled transmit/receive units.
In our previous international patent application number (PCT/AU2006/000311), a focusing scheme is described for a multi-element RF system that can increase the quality of images obtained for local regions of interest. The invention is described with reference to a number of small local coils with particular application to the head and chest.
Multi-element RF coils designed for active parallel transmission can be broadly classified into two categories. Multi-element RF coils which are specifically designed for the transmission only of the spatially selective pulses, while having a secondary receive-only RF coil for the reception of the excited MR signals, or, as a transceive system which can be used for transmission and reception simultaneously. The latter having the advantage of not requiring additional RF coils.
One common design element that all multi-element RF coils share is that some form of mutual decoupling method is employed to decouple the coil elements. A multi-element RF coil usually displays strong mutual coupling between individual coil elements. Some of the undesirable effects include difficulty in tuning and reduced SNR. RF field distortion is also a cause of image artefacts. Hence, minimizing mutual coupling is important.
In our pending international patent application number PCT/AU2008/000245, a counter wound inductor decoupling method is described for minimizing mutual coupling. The invention is described with reference to a number of local coils with particular application to the head. In the new coil structure described herein we preferentially use this method of decoupling, however, other methods of decoupling may be used with the new coil structure. The content of the previous application is incorporated herein by reference.
One other important consideration is the structural design of the coil element itself, the goal being a shape which can produce the highest possible RF field inside a conductive sample. This is crucial for active RF shimming, since ideally sufficient RF energy needs to be presented over the entire region of the sample to successfully excite protons over any region-of-interest (ROI). As the effective penetration depth of the RF field is proportional to the size of the coil element it is sometimes difficult to achieve the desired energy distribution, especially when the ROI is in the centre of the sample.
Irrespective of the applications (e.g. human or pre-clinical imaging) the design principles of a multi-element transmit and/or receive RF system remain the same. With strong spatial constraints, however, conventional coil structures can fail to produce a homogeneous RF field profile and even prove physically infeasible to construct. New designs are required.
It is an object of the invention to provide a coil design for a multi-element RF system.
It is a further object to provide a coil design with good RF field penetration and reduced mutual coupling effects such that coil elements can be substantially decoupled.
The invention is well suited for transceiver, multi-element RF systems for active parallel transmission MRI applications. The RF coil systems can also be used for transmit-only and receive-only multi-element RF coils for partial parallel imaging applications.
Further objects will be evident from the following description.
In one form, although it need not be the only nor indeed the broadest form, the invention resides in a radio frequency coil comprising:
multiple volumetric trough-shaped coil elements arranged about an imaging space;
each volumetric trough-shaped coil element comprising radiating structures aligned at an angle relative to a tangent of the imaging space.
The radio frequency coil design is preferably adapted for magnetic resonance imaging.
Suitably the imaging space is cylindrical and the multiple volumetric trough-shaped coil elements are arranged about the circumference of the cylindrical space. Each radiating structure is suitably angled relative to a tangent of the circumference of the cylindrical space.
The radiating structures are suitably rectangular and the long side of the radiating structure is angled relative to a tangent to the circumference of the cylindrical space.
The angularly oriented radiating structures may further comprise distributed inductance and capacitance elements. Furthermore, the inductance and capacitance elements are suitably incorporated in each volumetric trough-shaped coil element and suitably oriented at an angle to enhance radio frequency field penetration to the space.
The distributed inductance and capacitance of the radiating structures may be adjusted so that the multi-element radio frequency coil can be used at ultra-high field strengths.
The volumetric trough-shaped coil elements may suitably comprise sub-elements.
To assist in understanding the invention, preferred embodiments will now be described with reference to the following figures in which:
In describing different embodiments of the present invention, common reference numerals are used to describe like features. The current invention has been applied to the design and construction of a 9.4T shielded 8-element parallel transceive RF coil for pre-clinical MRI.
The transceive RF coil has been numerically modelled and a prototype constructed as described below. The invention is, however, not limited to animal MRI multi-element parallel transceive type of RF coils but can be applied to all multi-element or volumetric types of MRI RF coils.
The shielded 8-element parallel transceive RF coil 15 consists of eight separate oblong coils 1, 2, 3, 4, 5, 6, 7, 8 as shown in
The imaging space 11 is not limited to being cylindrical although this is an appropriate shape for most relevant applications.
Each volumetric trough-shaped coil element comprises two radiating structures 13. The radiating structures of each volumetric trough-shaped coil element 1, such as shown in
Numerical Modelling
Based on a conceptual consideration of angularly orienting the long side radiating structures of each volumetric trough-shaped coil element relative to a tangent of the imaging space, a combined finite difference time domain (FDTD) and hybrid method of moments (MoM)/finite element method (FEM) method are employed for modelling and analysis. The FDTD software, an in-house product, is used for seeking the general resonator layout, while MoM/FEM software, commercially available from FEKO (EMSS, Stellenbosch, South Africa), is employed for the theoretical validation of coil performance.
Initially, FDTD is used for searching the optimum angle α to which the long side radiating structures 13 of all eight elements will be oriented relative to a tangent of the cylindrical imaging space 11. At this step, during the full-wave field calculation, the coil structure is replaced by ideal current sources assuming all the volumetric trough-shaped coil elements are resonant and can be replaced by identical current. The FDTD software is integrated with a nonlinear least square optimization algorithm to achieve maximum RF field at the centre of the cylindrical imaging space 11, by adjusting the orientation angle α. Note that during the FDTD optimisation process, the loading effect (tissue-equivalent phantom) and RF shielding is fully considered and accounted for.
Once the optimum angle α is determined, a full-wave hybrid MoM/FEM based RF simulation program, is then employed for modelling the realistic shielded 8-element parallel transceive RF coil and also used for calculating the RF field and the mutual coupling inside the same phantom. The rationale in using hybrid MoM/FEM method for modelling the transceive RF coil is described in our pending international patent application number PCT/AU2008/000245.
Depicted in
Maximizing the RF Field
To demonstrate that the invention can increase the RF field penetration, four RF fields calculated using four different structured coil elements, where their long side radiating structures 13 are oriented to four different angles, are calculated and compared. Only one single element is analytically simulated for this comparison purpose.
Shown in
Using the modelled four different structured coil elements of
To further exemplify the embodiment, sensitivity data taken along the dotted white lines 20 of
A further advantage of the invention is that it can reduce the capacitive coupling between the RF system and the sample. Referring to
Regulating Mutual Coupling
The invention has the advantageous feature of being able to regulate the amount of mutual coupling between neighbouring volumetric trough-shaped coil elements. If mutual coupling can be reduced before the implementation of any decoupling methods, it will increase the efficiency of the decoupling methods, allowing mutual coupling to be easily minimized and importantly achieving a higher decoupling power. Persons skilled in the art will appreciate and understand that it will certainly simplify the design and construction of any multi-element RF coil if the mutual coupling between neighbouring volumetric trough-shaped coil elements is small.
To demonstrate that the invention can regulate the amount of mutual coupling, mutual coupling between two radiating structures of volumetric trough-shaped coil elements 27, 28, 29, as shown in
Mutual coupling between two volumetric trough-shaped coil elements causes dual minimums 22, 23 or a ‘splitting’ of the resonance frequency, as shown in
Demonstration
To demonstrate that the invention can increase the RF field and regulate mutual coupling, a 9.4T shielded 8-element parallel transceive RF coil, as shown in
Once each volumetric trough-shaped coil element is tuned to 400 MHz, matched to system impedance of 50Ω and mutually decoupled, the magnetic fields inside the cylindrical phantom 14 with an axial plane (xy plane) profile, located at the mid section, are calculated. The magnetic field profiles are calculated by exciting the transceive RF coil in a birdcage-like excitation mode, that is, all volumetric trough-shaped coil elements are excited with similar voltage amplitude but having phases with an increment of 45°. Following the principle of reciprocity [Hoult, Concepts Magn Reson 12(4) pg 173-187, 2000], the transmission fields {circumflex over (B)}1t+ and reception fields {circumflex over (B)}1r− can then be calculated by
With the RF profiles calculated by the hybrid MoM/FEM algorithm, the MR images for a cylindrical phantom can then be simulated and compared with the one acquired in parallel using the constructed prototype shown in the results section.
Prototype
A prototype of the shielded 8-element transceive RF coil 24 was constructed and is shown in
The invention permits the distributed inductance and capacitance of the radiating structure to be adjusted, allowing the multi-element transceive RF coil to be used at ultra-high field strength. This is important for ultra-high frequency RF coils, in cases where the desired capacitors are not commercially available. To achieve these adjustments, part of the copper strip on the top-side of the long side radiating structure is removed, forming a gap 25 as shown in
Results
The prototype 24 was tested in a Bruker 9.4T Avance III spectrometer MRI system with 8 transmit and receive channels. Four MRI experiments were undertaken to test the prototype. The first experiment is to obtain the sensitivity profile of each volumetric trough-shaped coil element. The prototype is loaded with a cylindrical phantom having the same dimensions and dielectric properties as the modelled cylindrical phantom 14 and one volumetric trough-shaped coil element is used for the transmission of the B1 field at any one time while all eight elements are used for the parallel reception of the excited MR signal. Shown in
In the second experiment, all volumetric trough-shaped coil elements of the prototype 24 loaded with a cylindrical phantom are simultaneously used for the transmission of the B1 field and concurrently used for the parallel reception of the excited MR signal. This shows the homogeneity of the RF field that can be obtained using the prototype 24 at ultra-high field. For the transmission of the B1 field, volumetric trough-shaped coil elements are excited in a birdcage-like excitation mode, similar to how it is excited in the simulation as discussed earlier. The parallel received MR signals are thereafter combined using a sum-of-square method, forming a composite image of the cylindrical phantom. Shown in
For the third experiment, the suitability of the prototype 24 for partial parallel imaging purposes is investigated. A GRAPPA parallel imaging reconstruction method with a reduction factor of 2 is applied to demonstrate parallel imaging is well suited and compliments the 8-element transceive RF coil designed using the invention. Detailed explanation on the operation of GRAPPA had been reported [Griswold et al, Magn Reson Med 47(6) pg 1202-1210, 2002]. Similar to the second experiment, all volumetric trough-shaped coil elements of the prototype 24 loaded with a cylindrical phantom are simultaneously excited in a birdcage-like excitation mode to transmit the required B1 field; however, during the parallel reception of the MR signal, every even numbered phase encoding data are not acquired. These missing data are reconstructed using GRAPPA. Shown in
For the fourth experiment, the prototype is tested for suitability for Transmit SENSE application. A chequerboard target pattern has been selected. Shown in
Shown in
As mentioned above, the radiating elements need not be rectangular.
Various other shapes are also possible for the radiating structures as shown in
The embodiments of
The embodiments of
The invention disclosed herein shows that a dedicated layout of the volumetric trough-shaped coil element structure relative to the sample and the shielding can maximise the RF field and reduce the mutual coupling effect. It can also reduce the capacitive coupling between the coils and the sample.
The invention is not limited to only orienting the long side radiating structure as demonstrated herein. Depending on the applications and importantly the advantages that one desires to gain from this invention, there are no bounded constraints in orienting any side or sides of the radiating structure and the angle to which it is oriented for dense array systems.
It will be appreciated that the embodiments described above utilizes eight transceive RF coils but the invention is not limited to such an arrangement or number of coils and can, without any limitations, be applied to the design of transmit and/or receive multi-element planar coil arrays or volumetric type of RF systems.
It will further be appreciated that the invention complements the applications of partial parallel imaging and accelerated spatially selective excitation.
Throughout the specification, the aim has been to describe the invention without limiting the invention to any particular combination of alternate features or any particular applications it can be implemented to.
Number | Date | Country | Kind |
---|---|---|---|
2008901638 | Apr 2008 | AU | national |
Filing Document | Filing Date | Country | Kind | 371c Date |
---|---|---|---|---|
PCT/AU2009/000422 | 4/7/2009 | WO | 00 | 12/5/2011 |
Publishing Document | Publishing Date | Country | Kind |
---|---|---|---|
WO2009/124340 | 10/15/2009 | WO | A |
Number | Name | Date | Kind |
---|---|---|---|
4751464 | Bridges | Jun 1988 | A |
4825162 | Roemer | Apr 1989 | A |
5280249 | Kess | Jan 1994 | A |
5347220 | Van Heelsbergen | Sep 1994 | A |
5483163 | Wen | Jan 1996 | A |
5489847 | Nabeshima | Feb 1996 | A |
6011393 | Kaufman et al. | Jan 2000 | A |
6087832 | Doty | Jul 2000 | A |
6285189 | Wong | Sep 2001 | B1 |
6377047 | Wong et al. | Apr 2002 | B1 |
7427861 | Bogdanov et al. | Sep 2008 | B2 |
7432711 | Du et al. | Oct 2008 | B2 |
7446528 | Doddrell et al. | Nov 2008 | B2 |
7646199 | Dannels et al. | Jan 2010 | B2 |
7859264 | Wosik et al. | Dec 2010 | B2 |
8022705 | Bogdanov | Sep 2011 | B2 |
8106656 | Wosik et al. | Jan 2012 | B2 |
8390287 | Crozier | Mar 2013 | B2 |
8598877 | Fujimoto | Dec 2013 | B2 |
8648597 | Habara et al. | Feb 2014 | B2 |
20030193380 | De Swiet | Oct 2003 | A1 |
20040155656 | Leussler | Aug 2004 | A1 |
20050062472 | Bottomley | Mar 2005 | A1 |
20060119358 | Doddrell et al. | Jun 2006 | A1 |
20060250125 | Bogdanov et al. | Nov 2006 | A1 |
20070085634 | Du et al. | Apr 2007 | A1 |
20070282194 | Wiggins | Dec 2007 | A1 |
20080211498 | Dannels et al. | Sep 2008 | A1 |
20090099444 | Bogdanov | Apr 2009 | A1 |
20100182009 | Crozier | Jul 2010 | A1 |
20100253347 | Habara et al. | Oct 2010 | A1 |
20110124507 | Wosik et al. | May 2011 | A1 |
20120074935 | Crozier et al. | Mar 2012 | A1 |
Number | Date | Country |
---|---|---|
10 2005 036513 | Aug 2006 | DE |
WO 2006094354 | Sep 2006 | WF |
WO 0194964 | Dec 2001 | WO |
WO 2005111645 | Nov 2005 | WO |
WO 2008104019 | Sep 2008 | WO |
WO 2009050650 | Apr 2009 | WO |
Entry |
---|
B.K. Li et al., “High Frequency Electromagnetic Analysis using Hybrid MOM/FEM Method”, Proceedings of the International Society for Magnetic Resonance in Medicine, 14th Scientific Meeting and Exhibition, Seattle, Washington, USA, May 6-12, 2006, Apr. 22, 2006, p. 699. |
Suwit Saekho et al., “Small Tip Angle Three-Dimensional Tailored Radiofrequency Slab-Select Pulse for Reduced B1 Inhomogeneity at 3 T”, Magnetic Resonance in Medicine 53:479-484 (2005). |
Ulrich Katscher et al., “Transmit Sense”, Magnetic Resonance in Medicine 49:144-150 (2003). |
D.I. Hoult, “The Principle of Reciporcity in Signal Strength Calculations—A Mathematical Guide”, Concepts Magn Reson 12: 173-187, 2000. |
Mark A. Griswold et al., “Generalized Autocalibrating Partially Parallel Acquisitions (GRAPPA)”, Magnetic Resonance in Medicine 47:1202-1210 (2002). |
Hiroyuki Fujita, “New Horizons in MR Technology: RF Coil Designs and Trends”, Magn Reson Med Sei, vol. 6, No. 1, pp. 29-42, 2007. |
Number | Date | Country | |
---|---|---|---|
20120074935 A1 | Mar 2012 | US |