The present invention is directed to blood pressure measurement through the use of sensor arrays capable of tracking changes to a signal, and recalibration based on said tracking.
In the field of blood pressure monitoring, one or more parameters are measured by a sensor in order to derive a patient's blood pressure. When monitoring a parameter (such as capacitance, resistance, current, voltage, optical signals, radar, ultrasound, etc.) from an object (such as the radial artery), movement of that object relative to the reference in any direction (x, y, or z axes), or disturbances from mechanical, electromagnetic, temperature, physiological, environmental, or other sources, can impact the data being captured, causing inaccuracies. It is necessary to detect when this motion, displacement, or disturbance is occurring, by how much, and properly account for them in a monitoring parameter. Prior systems teach a second sensing parameter to directly measure the degree of disturbance, such as radar, ultrasound, optical, accelerometers, gyroscopes, or other sensing parameters that are different from the target sensing parameter. The use of a second sensing parameter requires the use of more energy and resources, causes prior systems to be more invasive overall, and may measure factors not affecting the blood pressure measurement. Thus, a present need exists for a blood pressure monitoring system capable of detecting displacement, motion, and other disturbance parameters by measuring the target sensing parameter alone.
It is an objective of the present invention to provide systems and methods that allow for detecting a change to a sensor by measuring a single sensing parameter, as specified in the independent claims. Embodiments of the invention are given in the dependent claims. Embodiments of the present invention can be freely combined with each other if they are not mutually exclusive.
The present invention features a system for tracking a measured physiological signal and utilizing spatiotemporal data to adjust the measured physiological signal for noise. In some embodiments, the system may comprise a sensor array. The sensor array may comprise a plurality of sensors, and each sensor may be capable of measuring one or more parameters. In some embodiments, each sensor of the plurality of sensors may comprise a pressure sensor (e.g. strain sensors), an optical sensor (e.g. infrared, visible light), an ultrasound sensor, a radar sensor, a spatiotemporal sensor, or a combination thereof. Each sensor may additionally be capable of measuring spatiotemporal properties. The one or more parameters measured by each sensor of the plurality of sensors may be an electrical or analog-to-digital signal selected from a group comprising a capacitance measurement, a resistance measurement, a current measurement, a voltage measurement, a radar measurement, an optical measurement, an ultrasound measurement, or a combination thereof. The system may further comprise an electronic board communicatively coupled to the sensor array. The electronic board may be capable of transmitting a plurality of parameter measurements from the sensor array to a computing device. The system may further comprise the computing device. The computing device may be capable of detecting a change to the sensor array based on the plurality of parameter measurements. The change to the sensor array may be detected by measuring an increased parameter reading from at least a first sensor of the plurality of sensors and a decreased parameter reading from at least a second sensor of the plurality of sensors compared to a baseline measurement. The baseline measurement may be established by the computing device based on an initial plurality of parameter measurements received by the electronics board.
The present invention features a method for tracking a measured physiological signal and utilizing spatiotemporal data to adjust the measured physiological signal for noise. In some embodiments, the method may comprise a sensor array comprising a plurality of sensors measuring a first and a second plurality of parameter measurements. Each sensor of the plurality of sensors may be capable of measuring one or more parameters. In some embodiments, each sensor of the plurality of sensors may comprise a pressure sensor, a spatiotemporal sensor, or a combination thereof. The single parameter measured by each sensor of the plurality of sensors may be an electrical or analog-to-digital signal selected from a group comprising a capacitance measurement, a resistance measurement, a current measurement, a voltage measurement, a radar measurement, an optical measurement, an ultrasound measurement, or a combination thereof. The method may further comprise an electronic board communicatively coupled to the sensor array transmitting the first and the second plurality of parameter measurements to a computing device. The method may further comprise the computing device establishing a baseline measurement based on the first plurality of parameter measurements. The method may further comprise the computing device detecting a change to the sensor array based on the second plurality of parameter measurements. The method may further comprise the computing device adjusting the baseline measurement based on the change to the sensor array. The change to the sensor array may be detected by measuring an increased parameter reading from at least a first sensor of the plurality of sensors and a decreased parameter reading from at least a second sensor of the plurality of sensors compared to a baseline measurement.
One of the unique and inventive technical features of the present invention is the adjustment of noise from a plurality of sensors through the use of spatiotemporal data. Without wishing to limit the invention to any theory or mechanism, it is believed that the technical feature of the present invention advantageously provides for more accurate measurement of the changes to the plurality of sensors due the exclusion of a wide variety of noise types. None of the presently known prior references or work has the unique inventive technical feature of the present invention.
For example, prior systems for adjusting signals from sensors for noise teach a method of redundant sensing. In the redundant sensing method, there are two or more similar sensors where one is measuring the signal and noise, while the other sensors are measuring just noise. It is possible in some applications where the noise signal can be subtracted out from the primary signal resulting in the primary signal. However, there are situations where the noise can have different magnitudes measured across all sensors including the primary sensor. In this case, the method for redundant sensing is inefficient.
Furthermore, the inventive technical feature of the present invention is counterintuitive. The reason that it is counterintuitive is because the inventive technical feature contributed to a surprising result. One skilled in the art would determine that if the noise varies in magnitude (including situations where one signal goes up and one goes down due to noise) across the sensors that it would be too difficult to utilize spatiotemporal information to filter out noise impacting the target signal for it to be worth implementing. Surprisingly, the present invention is able to implement a spatiotemporal mesh that is able to identify noise. even in large quantities or with variable magnitude, and filter it from the target signal to provide a more accurate final signal than prior systems. Thus, the inventive technical feature of the present invention contributed to a surprising result and is counterintuitive.
Any feature or combination of features described herein is included within the scope of the present invention provided that the features included in any such combination are not mutually inconsistent as will be apparent from the context, this specification, and the knowledge of one of ordinary skill in the art. Additional advantages and aspects of the present invention are apparent in the following detailed description and claims.
The features and advantages of the present invention will become apparent from a consideration of the following detailed description presented in connection with the accompanying drawings in which:
Following is a list of elements corresponding to a particular element referred to herein:
The present invention applies an array of original single-parameter sensors to serve as an array of reference points that allows the present invention to indirectly measure the degree of displacement or motion without having to use a different sensing parameter to directly measure it. The present invention is additionally able to detect temperature, electromagnetism, or any other environmental parameter, analyze their impact on the signals gathered from the plurality of parameter measurements, and subtract this noise from the parameter measurements to allow for a more accurate final product. This technique allows for a system to simultaneously track the signal changes from each point on the array to determine if the object has moved or been displaced. An algorithm-based approach is then used to translate the detected signal changes across the array to deduce the direction and magnitude of the displacement and differentiate displacement-caused signal changes from real physiological-caused signal changes. The present invention uses an array of sensors that independently do not measure motion/displacement and apply them in a way to measure motion/displacement without the need to integrate a different type of sensor (such as optical sensors, accelerometers, or gyroscopes). The entire array of sensors can be used to deduce whether displacement is occurring, triangulate between the different sensors the actual magnitude of the displacement, and reset or re-calibrate the signal accordingly. The sensor array may comprise at least two individual sensors. In some embodiments, a sensors array comprises 6 to 10 sensors. A size of each sensor may be 2 mm to 3 mm by 2 mm to 3 mm.
The present invention features a system (100) for tracking a measured
physiological signal and utilizing spatiotemporal data to adjust the measured physiological signal for noise. In some embodiments, the system (100) may comprise a sensor array (200). The sensor array (200) may comprise a plurality of sensors, and each sensor (201) may be capable of measuring one or more parameters. In some embodiments, each sensor of the plurality of sensors may comprise a pressure sensor capable of measuring capacitance, resistance, current, and/or voltage, a spatiotemporal sensor capable of measuring optical, radar, and/or ultrasound signals, or a combination thereof. The single parameter measured by each sensor of the plurality of sensors may be an electrical or analog-to-digital signal selected from a group comprising a capacitance measurement, a resistance measurement, a current measurement, a voltage measurement, a radar measurement, an optical measurement, an ultrasound measurement, or a combination thereof. The system (100) may further comprise an electronic board (300) communicatively coupled to the sensor array (200). The electronic board (300) may be capable of transmitting a plurality of parameter measurements from the sensor array (200) to a computing device (400). In some embodiments, the electronic board (300) may transmit the plurality of parameter measurements to the computing device (400) through low-energy Bluetooth transmissions. The system (100) may further comprise the computing device (400). The computing device (400) may be capable of detecting changes to the sensor array (200) based on the plurality of parameter measurements. The changes to the sensor array (200) may comprise movement (e.g. displacement), environmental features (e.g. temperature), or a combination thereof.
Changes to the sensor array (200) may be detected by measuring an increased parameter reading or a decreased parameter reading from one or more sensors of the plurality of sensors compared to the baseline measurement. The baseline measurement may be established by the computing device (400) based on an initial plurality of parameter measurements received by the electronics board (300). The computing device (400) may be capable of deriving a spatiotemporal data set from the plurality of parameter measurements, detecting noise in the spatiotemporal data set, and adjusting, based on the plurality of parameter measurements, the baseline measurement with respect to the noise. In some embodiments, the computing device (400) may be further capable of converting a measurement into a blood pressure measurement. In some embodiments, the measurement may comprise an electrical or analog-to-digital signal selected from a group comprising a capacitance measurement, a resistance measurement, a current measurement, a voltage measurement, a radar measurement, an optical measurement, an ultrasound measurement, or a combination thereof. In some embodiments, the system (100) may further comprise an attachment component connected to the sensor array (200) for attaching the sensor array (200) to an external surface. The attachment component may be selected from a group comprising a strap and an adhesive. The external surface may be a portion of skin covering a carotid artery, a radial artery, or any other artery near the surface of the skin or another layer such as or including surgical dressing disposed on a portion of skin of the patient. In some embodiments, the electronic board (300) may further comprise an adaptive filter for filtering noise, creep, hysteresis, motion, temperature, electromagnetic signals, intrinsic sensor noise (e.g. sensor drift), or a combination thereof from the plurality of parameter measurements (see
In some embodiments, the computing device (400) may be further capable of measuring pulse transit time (PTT) between a first sensor of the plurality of sensors and a second sensor of the plurality of sensors. An example of this can be seen in
Referring now to
Changes to the sensor array (200) may be detected by measuring an increased parameter reading or a decreased parameter reading from one or more sensors of the plurality of sensors compared to the baseline measurement. In some embodiments, the second memory component (403) may further comprise instructions for converting the measurement into a blood pressure measurement. In some embodiments, the measurement may comprise an electrical or analog-to-digital signal selected from a group comprising a capacitance measurement, a resistance measurement, a current measurement, a voltage measurement, a radar measurement, an optical measurement, an ultrasound measurement, or a combination thereof. In some embodiments, the system (100) may further comprise an attachment component connected to the sensor array (200) for attaching the sensor array (200) to an external surface. The attachment component is selected from a group comprising a strap and an adhesive. The external surface may be a portion of skin covering a carotid artery, a radial artery, or any other artery near the surface of the skin or another layer such as or including surgical dressing disposed on a portion of skin of the patient. In some embodiments, the electronic board (300) may further comprise an adaptive filter for filtering noise, creep, hysteresis, motion, temperature, electromagnetic signals, intrinsic sensor noise (e.g. sensor drift), or a combination thereof from the plurality of parameter measurements (see
In some embodiments, the first communication component (301) may comprise a wired connection between the sensor array (200) and the electronic board (300), a wireless connection between the sensor array (200) and the electronic board (300) such that the sensor array (200) comprises a wireless transmitter and the electronic board (300) comprises a wireless receiver. The wireless connection may comprise Bluetooth, LoRa, radiofrequency, or any other kind of wireless communication type. In some embodiments, the second communication component (401) may comprise a wired connection between the electronic board (300) and the computing device (400), a wireless connection between the electronic board (300) and the computing device (400) such that the electronic board (300) comprises a wireless transmitter and the computing device (400) comprises a wireless receiver. The wireless connection may comprise Bluetooth, LoRa, radiofrequency, or any other kind of wireless communication type.
Referring now to
Changes to the sensor array (200) may be detected by measuring an increased parameter reading or a decreased parameter reading from one or more sensors of the plurality of sensors compared to the baseline measurement. In some embodiments, the method may further comprise the computing device (400) converting a measurement into a blood pressure measurement. In some embodiments, the measurement may comprise an electrical or analog-to-digital signal selected from a group comprising a capacitance measurement, a resistance measurement, a current measurement, a voltage measurement, a radar measurement, an optical measurement, an ultrasound measurement, or a combination thereof. In some embodiments, may further comprise attaching, by an attachment component connected to the sensor array (200), the sensor array (200) to an external surface. The attachment component may be selected from a group comprising a strap and an adhesive. The external surface may be a portion of skin covering a carotid artery, a radial artery, or any other artery near the surface of the skin or another layer such as or including surgical dressing disposed on a portion of skin of the patient. In some embodiments, the method may further comprise an adaptive filter filtering noise, creep, hysteresis, motion, temperature, electromagnetic signals, intrinsic sensor noise (e.g. sensor drift), or a combination thereof from the plurality of parameter measurements (see
The present invention features a system (100) for tracking a measured physiological signal and utilizing spatiotemporal data to adjust the measured physiological signal for noise. In some embodiments, the system (100) may comprise a sensor array (200) comprising a plurality of sensors. Each sensor (201) may be capable of measuring one or more parameters. The system may further comprise an electronic board (300) communicatively coupled to the sensor array (200). In some embodiments, the electronic board (300) may comprise a first communication component (301), a first processor (302) capable of executing computer-readable instructions, and a first memory component (303) comprising computer-readable instructions. In some embodiments, the computer-readable instructions may comprise receiving, from the sensor array (200), a plurality of parameter measurements, and transmitting, by the first communication component (301), the plurality of parameter measurements. The system may further comprise a computing device (400) communicatively coupled to the electronic board (300). In some embodiments, the computing device (400) may comprise a second communication component (401), a second processor (402) capable of executing computer-readable instructions, and a second memory component (403) comprising computer-readable instructions. In some embodiments, the computer-readable instructions may comprise receiving, by the second communication component (401), a first plurality of parameter measurements and a second plurality of parameter measurements from the electronic board (300), establishing, based on the first plurality of parameter measurements, a baseline measurement, detecting, based on the second plurality of parameter measurements, a change to the sensor array (200), and adjusting, based on the change to the sensor array (200), the baseline measurement. The change to the sensor array (200) may be detected by measuring an increased parameter reading from at least a first sensor of the plurality of sensors and a decreased parameter reading from at least a second sensor of the plurality of sensors compared to the baseline measurement. The computer-readable instructions may further comprise measuring pulse transit time between a first sensor of the plurality of sensors and a second sensor of the plurality of sensors, and analyzing a pulse wave gathered by one or more sensors of the plurality of sensors. Analyzing the pulse wave gathered by one or more sensors of the plurality of sensors further comprises extracting amplitude, phase, frequency, systolic blood pressure, diastolic blood pressure, dicrotic notch, a time difference between systolic and diastolic peaks, a rate of blood pressure change between systolic and diastolic peaks, a minimum blood pressure change between systolic and diastolic peaks, heart rate, heart rate variability, or a combination thereof from the pulse wave.
Referring now to
A sensor of the sensor array may comprise a pressure sensor, an electromagnetic sensor (e.g an optical sensor, an ultrasound sensor, a radar sensor), a capacitive sensor, a resistive sensor, or a combination thereof. Each sensor may additionally comprise a thermometer, an accelerometer, a gyroscope, a magnetometer, a bioimpedance sensor, or a combination thereof, which may be auxiliary to the primary function of each sensor. Note that the presently claimed invention may be capable of measuring displacement and detecting disturbances affecting the displacement reading. Non-limiting examples of displacement measured by the present invention include movement of an artery relative to the array of sensors, such as the movement of a pulse throughout the body or wave propagation data detected by measuring when the artery expands in one area and pulls down in another. Non-limiting examples of disturbances detected by the present invention include environmental noise that affects one or more sensors similarly (e.g. temperature, electromagnetism), noise caused by surface topography (e.g. each sensor of the sensor array being placed on different inclines), and gradient noise that moves across one or more sensors. The present invention is capable of detecting these disturbances in the signals received from the sensor array and use spatiotemporal data to filter them from the plurality of sensors, thus resulting in a more accurate final product with less noise than that achieved by prior systems.
Instructions that cause at least one processing circuit to perform one or more operations are “computer-readable.” Physical storage media (memory components) includes RAM and other volatile types of memory; ROM, EEPROM, and other non-volatile types of memory; CD-ROM, CD-RW, DVD-ROM, DVD-RW, and other optical disk storage; magnetic disk storage or other magnetic storage devices; and any other tangible medium that can store computer-executable instructions that can be accessed and processed by at least one processing circuit. Transmission media can include signals carrying computer-executable instructions over a network to be received by a general-purpose or special-purpose computer.
Although there has been shown and described the preferred embodiment of the present invention, it will be readily apparent to those skilled in the art that modifications may be made thereto which do not exceed the scope of the appended claims. Therefore, the scope of the invention is only to be limited by the following claims. In some embodiments, the figures presented in this patent application are drawn to scale, including the angles, ratios of dimensions, etc. In some embodiments, the figures are representative only and the claims are not limited by the dimensions of the figures. In some embodiments, descriptions of the inventions described herein using the phrase “comprising” includes embodiments that could be described as “consisting essentially of” or “consisting of”, and as such the written description requirement for claiming one or more embodiments of the present invention using the phrase “consisting essentially of” or “consisting of” is met.
The reference numbers recited in the below claims are solely for ease of examination of this patent application, and are exemplary, and are not intended in any way to limit the scope of the claims to the particular features having the corresponding reference numbers in the drawings.
This application is a continuation-in-part and claims priority to PCT Application No. PCT/US2022/015823 filed Feb. 9, 2022, which claims priority to U.S. Provisional Application No. 63/147,396 filed Feb. 9, 2021, the specifications of which are incorporated herein in their entirety by reference.
Number | Date | Country | |
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63147396 | Feb 2021 | US |
Number | Date | Country | |
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Parent | PCT/US22/15823 | Feb 2022 | US |
Child | 18447128 | US |