The present invention relates to an optical interferometer which can be used to provide simultaneous measurements and simultaneous optical coherence tomography (OCT) images over multiple path lengths, using principles of low coherence interferometry or spectral interferometry.
There is an interest in OCT of speeding up the acquisition to cope with moving targets. Also, in the field of sensing, there is a need to collect data from multiple points simultaneously. The configurations disclosed in patent number U.S. Pat. No. 6,775,007 B2 by Izatt et al. employ versions of cascaded Mach-Zehnder interferometers in conjunction with frequency shifters to create multiple path length differences associated with unique frequencies. Such a configuration presents the following disadvantages: (i) different states of polarization cannot be associated with unique carrier frequencies; (ii) in integrated formats, optical delays cannot be easily adjusted; (iii) after passing a train of cascaded interferometers, the intensity in channels corresponding to different carrier frequencies present unequal optical intensities. As each phase element introduces a separate frequency shift, the configuration is complex and not reconfigurable in terms of functionality.
The article “Acousto-optically switched optical delay lines” published by Naabel A. Riza in Optics communications 145 (1998), pages 15-20 presents several configurations of optical delay lines devised for telecommunications that employ acousto-optic deflectors to scan and de-scan the laser beam to achieve different delays. Such an embodiment has the following disadvantages: (i) employs a single frequency with spectral scanning in time to achieve different delays, a procedure that is time consuming; (ii) different polarization states that cannot be associated with unique carrier frequencies.
In order to speed up the acquisition of time domain (TD)-OCT, a method and systems are disclosed in the PCT application WO/2009/106884A1 UKPO, 0803559.4, and US US20110109911 by Podoleanu, where an active recirculating loop is placed in each interferometer arm together with a frequency shifter, where the two frequency shifters are driven at different frequencies so as to encode signal from successive depths in the object investigated on the frequency difference between the two frequencies, and where the depth positions are separated by the differential optical path difference of the two recirculating loops. To alleviate the attenuation at each round trip, optical amplification is used. Despite the employment of amplifiers in the secondary loops to compensate for losses, only up to twenty recirculations could be produced and good signal to noise ratio images from five depths only could be obtained, as presented in the paper Multiple-depth en-face optical coherence tomography using active recirculation loops, published by L. Neagu, A. Bradu, L. Ma, J. W. Bloor and A. Gh. Podoleanu in Optics Letters Vol. 35, No. 13/Jul. 1, 2010, pp. 2296-2298. Two major causes for failure to achieve more channels is believed to be due to the ASE built up in the secondary loops and also owing to polarization mismatch.
The configurations disclosed in the patent by Podoleanu above presents the following disadvantages:
Sequential collection of images is performed in the practice of structured illumination microscopy, as described in “Structured interference optical coherence tomography” by Ji Yi, Qing Wei, Hao F Zhang, and Vadim Backman published in Optics Letters, 37/15, 2048-3050, 2012. In this paper, 10 frames of spectral OCT images are collected, for 10 different phases of the modulation pattern created in the image by rotating a chopper in the reference arm. The disadvantage of such method is that sequential collection of images takes time, which renders it inappropriate for moving targets. It would save time if all mages were collected simultaneously.
Another problem is that of decay of sensitivity with depth in spectral OCT. A multiple path configuration with secondary loops in each interferometer arm, as disclosed in US US20110109911, was demonstrated in the paper “Extra long imaging range swept source optical coherence tomography using re-circulation loops”, published in Opt. Express 18, 25361-25370 (2010), by A. Bradu, L. Neagu, A. Podoleanu. This could reduce the decay with depth. However, the method presents the disadvantage of ASE and cost, and while the method can enlarge the axial range of spectral OCT by a large number, over 20-100 times the axial range in a conventional OCT configuration, in practice, extension by a factor of 2-3 of the axial range only would suffice.
The present invention therefore seeks to overcome the above disadvantages, by providing novel enhanced configurations and methods of operation. The novel features incorporated herewith lead to more uniformity between at least some of the channels corresponding to different depths, better control of polarization for at least a limited number of channels and better efficiency in using the signal. The present invention ensures that from within at least some adjacent layers in depth, the strength of signal is similar and strong. In addition, some of the embodiments disclosed are reconfigurable, allowing different functionality to be achieved with minimum changes.
Simultaneous collection of images for multiple depth interrogation, multiple polarization interrogation, structured illumination and despeckle are achieved in more compact, lower cost, lower noise embodiments.
In spectral interferometry embodiments proposed, constant decay with depth or lower attenuation with depth is obtained by using a limited number of parallel channels which make such embodiments more compact and confer such embodiments lower cost.
In a majority of embodiments disclosed here, the depth is encoded on the pulsation frequency of the interference photodetected signal. By providing extra means to encode the depth, where the frequency shifters are placed outside the optical rings, more compact rings and lower costs configurations are allowed, with further functionality.
In the prior art documents mentioned above, frequency shifters are driven at fixed frequencies. This limited the functionality of the interferometers. In some of the embodiments presented, by chirping the frequency shifts when applying frequency shifting of signals to be interfered, more functionality is obtained as presented below, further alleviating the disadvantages of the known technologies.
In a first aspect, the present invention discloses optical interferometer configurations that can provide interference along parallel optical delays. Such configurations can be customized to ensure that a number of OCT channels simultaneously provide signal from several optical path differences within a sensing volume, all exhibiting similar strength.
In a second aspect, the present invention provides means for ensuring that a number of channels provide signal from the same depth, but with different polarization states, all exhibiting similar strength. Such means can be used to produce simultaneous polarization measurements from a given axial position within the sensing volume or a polarization sensitive OCT image from a given depth in the object investigated. The invention can also be used to supply polarization data from several depths simultaneously.
In a third aspect, the invention relates to interferometer configurations where means of creating parallel delay paths, that ensure similar signal strength, are combined with means of creating roundtrip paths, characterized by decaying signal strength.
In a fourth aspect, the invention provides a novel optical source for the multiple path configuration, where the source itself contains multiple paths that in combination with the multiple paths in the reference path of the interferometer can simultaneously provide signals from several axial positions in the object investigated.
In a fifth aspect, the present invention provides interferometer configurations containing multiple delays interleaved between frequency shifters driven by signals with synchronized chirping that are employed to encode the axial position in an object, on the frequency of the interference signal resulting from interfering delayed chirped signals.
In a sixth aspect, the invention discloses methods for encoding axial depths in an object on the frequency of the interference signal, resulting from frequency shifting of parallel optical beams traversing different optical path depths in the interferometer.
In a seventh aspect, the invention discloses methods for encoding polarization states of signals returned from different depths and where polarization and depth information are encoded on the frequency of the photodetected interference signal.
In an eighth aspect, the invention protects the combination of chirping the optical frequency of the optical signals in the two interferometer arms, with principles of low coherence interferometry or spectral interferometry.
In a ninth aspect, the invention presents methods to encode axial distances in the object to be investigated by a multiple delays interferometer while synchronously chirping the frequency of the interfering signals.
In a tenth aspect, a multiple phase element is disclosed, where different optical lengths are provided in parallel in multiple beams between two acousto-optic modulators, each driven by a beam of a different frequency as determined by the frequency of signals applied to the two modulators.
In an eleventh aspect, a multiple phase element is disclosed, where different optical lengths are provided in multiple beams between an acousto-optic modulator driven by a set of multiple frequencies, and a mirror.
In a twelfth aspect, a polarization sensitive multiple phase element is disclosed, traversed by both the interfering beams in a two beam interferometer.
In a thirteenth aspect, the invention presents methods to employ a tunable laser source and multiple paths to provide multiple depth imaging and multiple depth measurements from an object.
In a fourteenth aspect, the invention discloses an apparatus and methods to provide constant sensitivity with depth or longer axial depth range in spectral OCT.
In a fifteenth aspect, the invention discloses a fast apparatus and methods to collect the multiple phase shifted images in structured illumination microscopy.
The novel features which are believed to be characteristic of the present invention, as to its structure, organization, use and method of operation, together with further objectives and advantages thereof, will be better understood from the following drawings in which a presently preferred embodiment of the invention will now be illustrated by way of example. It is expressly understood, however, that the drawings are for the purpose of illustration and description only and are not intended as a definition of the limits of the invention. Embodiments of this invention will now be described in association with the accompanying drawings in which:
a shows a detailed diagram of the multiplexer in
b shows a detailed diagram of the multiplexer in
c shows a detailed diagram of a multiplexer as a combination of those in
d shows, in diagrammatic form, a second embodiment according to the invention, of a multiplexer using frequency shifted multiple paths.
e shows, in diagrammatic form, another version of the second embodiment according to the invention, of a multiplexer using frequency shifted multiple paths.
f shows, in diagrammatic form, yet another version of the second embodiment according to the invention, of a multiplexer using frequency shifted multiple paths.
g shows, in diagrammatic form, a multiplexer according to the invention, containing any of embodiments 2a,b,c,d,e or f above, in series with an active ring.
h shows, in diagrammatic form, a multiplexer according to the invention, containing an active ring that includes a multiplexer according to the embodiment in
i shows, in diagrammatic form, a multiplexer according to the invention, containing a multiple phase element implemented as a passive ring, combined with a multiplexer according to the embodiment in
j shows, in diagrammatic form, a multiplexer according to the invention, containing a multiple phase element implemented as a passive ring in series with a frequency shifter.
a shows a detailed diagram of a first embodiment of the apparatus according to the invention based on the embodiment in
b shows a detailed diagram of a second embodiment of the apparatus according to the invention based on the embodiment in
a shows in diagrammatic form, a third embodiment of the apparatus according to the invention, based on a multiplexer disclosed in
b shows in diagrammatic form, the succession of interference wave trains output of the apparatus in
c shows in diagrammatic form, another version of the third embodiment of the apparatus according to the invention, similar to that in
a shows in diagrammatic form, a fourth embodiment of the apparatus according to the invention, based on a multiplexer as disclosed in
b shows the intensity of frequency of the multiple interference terms created by the embodiment in
c lists the frequency and optical path pairs created by the embodiment in
d shows in diagrammatic form, another version of the fourth embodiment of the apparatus according to the invention, similar to that in
a shows in diagrammatic form, a seventh embodiment of the apparatus according to the invention where the frequency shifting is placed outside the multiple phase element.
b shows the theoretical power output from a ring based on a single coupler design for two values of the cross coupling ratio relative to the power of the input pulse, left: 10% and right: 1%.
c shows another version of the embodiment in
a shows in diagrammatic form, an eight embodiment of the apparatus according to the invention, where the frequency shift is outside the multiple phase element, based on blocks as disclosed in
b shows in diagrammatic form, the succession of interference wave trains output of the embodiment in
a shows a ninth embodiment of the apparatus according to the invention, where frequency shifting is outside the multiple phase element and frequency chirping is used.
b presents the temporal variation of the frequency shifts of the two frequency shifters in
c shows another version of the embodiment in
d presents the temporal variation of the frequency shifts of the two acousto-optic frequency shifters in
Various features of the present invention, as well as other objects and advantages attendant thereto, are set forth in the following description and the accompanying drawings in which like reference numerals depict like elements.
All lengths below are optical and they include the index of refraction of the fiber link or air or of the object.
Characteristic to the invention, is that each element in 25 is traversed by a wave from 23 of distinct optical frequency. As disclosed below, the combination of frequency shifter and multiple phase element 25 can be implemented in parallel, where 23 creates spatially diverse waves, in parallel, each traversing a different phase element in an array 25 of phase elements.
A sequential implementation is also disclosed, where 23 is driven by a signal with chirped frequency and as consequence, sends waves of different optical frequencies, where sequentially, different phases are interrogated, created by an optical ring implementation of 25. To compensate for dispersion, a block 2′ is inserted in the reference path, incorporating similar elements as those employed in 2 depending on the particular embodiment. Multiple measurements in the object 69 are performed based on the frequency characterizing the wave traversing each phase element in 25. They are decoded using a decoder 91. The multiple measurements refer to multiple depths in the object 69, or multiple polarization information from the same depth, or a combination of several depth characterized in terms of polarization, or multiple phases for despeckle, or multiple phases/and or polarization for structured light. An optical path difference in the main loops, OPDM refers to the difference of paths between the main paths.
In terms of polarization control and more uniform decay from one channel to the next, an embodiment according to the present invention for the multiplexer, 2, with delays in parallel, is disclosed in
In principle, more than 8 RF signals of different frequencies can be applied to AOMs, the only limitation being the RF power accepted by the crystals. As presented below, if two signals only are used, then these allow polarization functionality, whilst 4 signals can deliver Stokes information and in principle, the parameters of a Mueller matrix can be measured by using up to 16 channels.
a discloses a first embodiment of the multiplexer using parallel paths. A frequency shifter, 23 is employed, implemented using an acousto-optic modulator (AOM) 23. The RF excitation of the AOM, 23 consists in a number of P radio frequency (RF) signals of different frequencies, fp, provided by a driver 64a. This produces angular spatial separation of P beams, according to the frequency of the signal applied to 23 by the driver 64a. The AOM 23 deflects the input beam 21 into P beams in different directions.
A first lens 26, placed at a distance equal to its focal length from the AOM 23, redirects the P beams parallel to each other before the multiple phase element 25a. A second lens 26 is positioned at a distance equal to the summation of focal lengths of lens 25 with focal length 26 and behind it, at a distance approximately equal to its focal length, a second AOM element, 24, is placed. The effect of the lens 26 and AOM 24 is to bring all diffracted beams along the same axis after the AOM 24, in a recombined beam in the first order diffracted light. To do this, the same set of signals is applied to 24 using a driver 64b, under control of an optional synchronizing generator 74. Screens 28 block the zero order beams at the outputs of the AOMs 23 and 24. Each diffracted beam, shifted in frequency by fp, is intercepted by a phase delay element 25a, made from P phase elements, placed between the lenses 25 and 26. Only four such phase elements are shown as an example in
The technology of AOMs is well known by the person skilled in the art. Typical drivers with synthesizers of eight frequencies whose frequency and phase can be easily controlled, are commercially available from Gooch and Housego, Fla., USA.
To avoid cross talk between the channels, the beams coming out of 23 need to be separated spatially by more than the incident beam diameter. Lens 26, therefore, needs to have a long focal length. This may, however, make the delay block 2a too long. The diagram in 2a may contain an extra focusing element, according to means known in the art, to compensate for the beam divergence coming out after the second lens 26, in order to reduce the size of the block 2a.
For measurement of Stokes parameters for instance, the four phase elements in 25a in
A simpler version of the embodiment in
Using the embodiment in
An embodiment of the apparatus according to the invention using blocks 2a in the two arms of an interferometer is shown in
A different implementation of the multiple phase element, 25b, is disclosed in
A combination of functionalities delivered by the embodiments in
Another version of a multiple delays block in reflection is disclosed in
Another version of a multiple delays block in reflection is disclosed in
All embodiments disclosed in
g shows another embodiment of the multiplexer, 2, using a splitter, 37, to launch light into a ring, 77, combined with any multiplexer according to the description in
Another embodiment, which combines a ring with parallel paths, is shown in
By using passive loops that can ensure little decay from one circulation to the next, there is no need for any optical amplification. The ASE problem is also eliminated by removing the optical amplifiers from the rings. To make such a scheme workable, frequency shifters are placed outside the rings to avoid losses and the scheme requires utilization of a power optical source 10, pulsated, with a pulse width τ, slightly less than the round trip time, Δt, in the loop.
j discloses a multiplexer containing a multiple phase element implemented as a passive ring, 44, in series with a frequency shifter, 23. In some embodiments, the frequency shifter is after the passive ring or before, without departing from the scope of the invention. In some other embodiments, the passive ring uses the multiple phase element 25d shown in
a discloses a detailed embodiment of the apparatus according to the invention. The light from the optical source block 1 is split into a reference arm (top) and an object arm (bottom) by a fiber beam splitter 7. A multiplexer based on the embodiment in
Light in the two arms is directed via polarization controllers 62a and 62a′, then via launchers 61 and 61′ containing lenses or converging mirrors towards two linear polarizers 27 and 27′ oriented so that the resulting linear polarization coincides with the required polarization of AOM elements, 23, 24 in 2a and 23′ and 24′ in 2a′ for optimal performance. In the reference arm, multiple phase gratings with different periods and adjustable contrasts are created in the AOM elements 23 and 24 by driving them with sinusoidal signals of different frequencies simultaneously. The beam in the reference arm passes a dispersion compensator element, 79, which compensates for the dispersion introduced in the object arm by extra elements, as presented immediately below, and is then injected into the fiber coupler 8, via a focusing element 61.
The light in the object arm passes through a similar combination of optical elements as in the reference arm to ensure minimal differential dispersion. The main difference is that AOM elements 23′ and 24′ are modulated at a single frequency only and there is no multiple phase element between the two lenses 26′. After the AOM 24′, a mirror 52 (this can be eliminated, drawn here to compact the sketch) is used to divert light towards a beam splitter 65, that directs part of the light onto an XY scanning mirror pair 67 and interface optics, shown as a lens 68, that focuses light on the object to be imaged, 69. The reflected light from the object 69 goes back through the interface optics 68, is then de-scanned by the XY mirror pair 67 and launched into the fiber input of the 2nd splitter, 8, by the focusing element 61′. Fiber polarization controllers, 62b and 62b′ are used to match the polarization in the two fiber arms of the fiber splitter 8, where interference takes place. A quarter wave plate, 51, in the main object arm, is oriented at 45 degrees with respect to the orientation of fast axis of linear polarizer 27′ to produce circular polarized light being sent to the object 69. Axial scanning is achieved by altering the main optical path difference, by moving the translation stage 81, carrying the lens 61 and reference fiber input of splitter 8.
The AOM elements 23 and 23′ are driven by drivers 64a and 64a′ respectively, and AOM elements 24 and 24′ by drivers 64b and 64b′. Drivers 64a′ and 64b′ are single frequency, while drivers 64a and 64b are multiple frequency. If the AOMs are used as Bragg cells, either in bulk or in fiber, they operate as frequency shifters, at typical frequencies F=40, 80, 160, 330 MHz while other values are equally possible.
The heterodyne photodected signal pulsates at a frequency ν determined by the frequency of signals applied to respectively 23, 2423′ and 24′:
ν=|F23+F24−F23′−F24′| (1)
Depending on the bandwidth of the measurement signal, in case the interferometer in
It is equally possible to use any of the frequency shifter to shift the frequency up, while the other frequency shifters shift the frequency down. This may be desirable in those circumstances where a large carrier frequency of the photodetected signal is required, such as hundreds of MHz to 1 GHz. AOM frequency shifters operating at over 300 MHz already exist. For the example considered above, the signal at the output of 9 pulsates at a frequency:
νp=pδν, p=1 to 8, δν=2 MHz (2a,b,c)
When P=2 phase elements are used in 25a, as presented above in relation to
φ(z)=ac tan(√{square root over (IV(z)/IH(z))}{square root over (IV(z)/IH(z))}), (3a)
The reflectivity:
R(z)˜IV(z)+IH(z), (3b)
can also be calculated and represents a polarization insensitive measurement. The optical axis orientation θ could be obtained by using the formula
θ=(180°−ΔΦ)/2 (3c)
where ΔΦ is the phase difference between the two channels, IH and IV. In sensing applications, the transversal scanner 67 is not necessary. For OCT imaging, the polarization information as described above is obtained for each pixel in transversal section as targeted by the object beam orientation, controlled by deflection in the XY scanner 67. If two phase elements only are used in 25, then, en-face OCT images are obtained: an image for birefringence, a polarization insensitive image, and eventually an en-face image with the axis orientation. When both scanners in the XY scanner 67 are used, en-face OCT images from different depths, controlled by the translation stage, 81, are generated, with polarization information. B-scan images can also be generated by using one scanner in the pair 67 at a fast line rate and the translation stage 81. Typical scanning speeds in en-face generation are obtained by driving the line scanner in the pair 67 at 500 Hz and the frame scanner in the pair 67 at 2 Hz. With 8 signals driving 23 and 24, 8 en-face OCT images with different polarization states from the same depth, controlled by translation stage 81, are obtained, simultaneously, in the time of 0.5 s required to generate a single en-face image.
As all frequencies vp are present at the same time at the output of 9, a decoder, 91, is used to separate the signals in the P channels. The decoder 91 can be assembled using several band pass filters tuned on frequencies vp. Alternatively, for each channel, a mixer can be used followed by a low pass filter, mixing the output signal from 9 with a signal of frequency pδν, derived from the drivers 64a, 64b, 64a′ and 64b′, using means known in the art of producing a mixed signal. As another alternative, a digitizer can be used to separately process signals in the imaging bandwidth around carriers vp, store data and allow visualization of any of the chosen channel or combination of channels later on.
b depicts a 2nd embodiment of the apparatus according to the invention that can supply information from several different depths, zp, simultaneously. To achieve such a functionality, the system described in
B-scan images can also be acquired using the translation stage 81 and one scanner only in the pair 67. The range covered by the translation stage D and the differential step 8 need to be correlated. Let us say that the translation stage 81 can be used to cover an axial range of D=1 mm In this case, δ is adjusted to be equal to D and P=8 B-scan images are generated, one from Z to Z+D, 2nd from Z+D to Z 30 2D, and so on up to P=8, covering in total an axial range Z to 8D in the same time as it would be taken by the conventional OCT method to create a B-scan of axial range D only.
In the operation of embodiments in
Applying only one RF signal to the AOM23 and 24 has the advantage of optical power distributed into a single channel only at a time. No cross talk between channels exists either.
It may also be found advantageous to work with a set of 4 channels sequentially switched to the next set of 4 channels for a total of P=8, or to switch 4 times, 2 channels, to the next 2 channels and so on.
The optimum number of simultaneous channels should be chosen depending on the available reference power. As shown in the papers: “Limitation of the achievable signal to noise ratio in OCT due to mismatch of the balanced receiver”, by C. C. Rosa, A. Podoleanu, published in Applied Optics, 43 (25): 4802-4815, 2004 and Unbalanced versus balanced operation in an OCT system, by A. Gh. Podoleanu, published in Appl. Opt., 2000, Vol. 39, No. 1, pp. 173-182, there is an optimum attenuation for the reference power needed to reduce the excess photon noise and maximize the signal to noise ratio. The power per channel in the reference path scales down with the number of parallel channels P, by P2. When the reference power is so high, that in order to reduce the excess photon noise, it needs to be attenuated by more than 64 times, there is room for P=8 channels. However, if the reference is sufficient to be attenuated by only 4 times to reduce the excess photon noise, then only P=2 channels simultaneously could be used without penalty in the signal to noise ratio due to decrease in the interference signal strength as result of lowering the reference power. Therefore, there is an optimum trade-off in terms of the P number of simultaneous channels and signal to noise ratio.
To adjust the reference power, the coupling efficiency of splitter 7 can be reduced towards the object arm. Maintaining the same safety level on the object 69, the optical power emitted by the optical source block 1 can be increased while the coupling efficiency towards the object arm is reduced correspondingly. In this way, power can be increased to be launched towards the reference path to compensate for the division of optical power in 23.
Sequential switching of the RF signals brings the disadvantage of enlarging the bandwidth of the signal per each channel. For instance, let us say that the en-face imaging takes place at 2 ms per T-scan line rate, with 200 pixels, this gives 10 μs per pixel. A sequential switch of P=5 channels requires 2 μs per each channel. This means that each channel is chopped on and off at a frequency of 100 kHz, with a delay of 2 μs between adjacent channels, and each channel is kept on for a 1/P=0.2 fraction of the time per each pixel. This reduces the strength of the signal per each channel by the same factor, but has the advantage of total elimination of cross talk.
In this way, a separate en-face OCT frame can be collected for each RF pair of frequencies applied to AOMs 23 and 24, taking advantage of full reference power per channel with the disadvantage of slowing down the acquisition.
The sequential procedure achieves an elegant solution of sequential electronic switching of polarization channels in
a presents a third embodiment of the apparatus according to the invention, where a combination of two multiplexers as disclosed in
νp,m=(2fp−fo)+mΔF. (4a)
For p=1, the frequencies of the driving signals can be adjusted to make 2f1−fo=0 and for the next values p, the fp+1−fp=δf. (4a) becomes:
νp,m=(p−1)δf+mΔF (4b)
The frequencies encode signals from depths:
z
p,m
=|pδ+m(LO−LR)| (4c)
The multiple channels produced by such a combination of delaying elements is illustrated in
The figures in the middle of
Alternatively, if the multiple phase element 25b is replaced with a polarization phase element 25a, creating two orthogonal polarisations, then the two signals I of frequencies ν1,1 and ν2,1 will give a polarization sensitive signal (image) at Δ, the two signals II will give a polarization sensitive signal (image) at 2Δ and so on. Polarization collection means in fact at least two pieces of information, in channels H and V, that can be put together to infer a polariation insensitive measurement of reflectivity (or image) and a birefringence signal (image). If phase control is stable between the two orthogonal polarizations, then a 3rd image can be produced, delivering the orientation of the birefringence axis in the object 69, as described above in connection with the embodiment in
c shows in diagrammatic form, another version of the third embodiment of the apparatus according to the invention. This is similar to that in
A fourth embodiment according to the invention is disclosed in
The frequencies of the signals applied to the two AOMs in the parallel paths are fp. In the block 2h′, two AOM 23′ and 24′ are shown, to compensate for dispersion of the two AOMs 23 and 24 in the multiplexer 2h. However, a single frequency shifter of total length to that of the AOMs in the reference arm can be used instead. Therefore, for simplicity, we will consider the effect of the two AOMs 23′ and 24′ as resulting from a single, third frequency shifter in the embodiment in
frequencies determined by:
νP,r(m)=Σi=1Psi,r(2fp−f0) (5b)
where
Σi=0Psi,r=m (5c)
For P=2, M=1, the two coefficients si,r, are (1,0), (0,1) which determine two distinct frequencies. For P=2, M=2, the two coefficients si,r, are (2,0), (1,1) and (0.2), which determine 3 more distinct frequencies. For P=2, M=3, the two coefficients si,r are (3,0), (2,1), (1,2), (0,3) which determine 4 more distinct frequencies. In total, 2+3+4=9 distinct frequencies out of 14 components. For P=2, M=4 the two coefficients si,r are (4,0), (3,1), (2,2), (1,3), (0,4) which determine 5 more distinct frequencies. In total, for P=2 and M=4, there are 2+3+4+5=14 distinct frequencies.
As another example, for P=3, M=1, the three coefficients si,r are (1,0,0), (0,1,0) and (0,0,1), which determine 3 distinct frequencies. For P=3, M=2, the three coefficients si,r are (2,0,0), (0,2,0), (0,0,2), (1,1,0), (0,1,1) and (0,1,1) which determine 6 more distinct frequencies. For P=3, M=3, the three coefficients si,r are (3,0,0), (2,1,0), (2,0,1), (1,2,0), (1,0,2), (1,2,0), (0,1,2), (0,2,1), (0,0,3), (0,3,0), (1,1,1), which determine 10 more distinct frequencies In total, 3+6+10=19 distinct frequencies out of 39 components.
For instance for only two phase elements in 25, P=2, the frequencies generated can be expressed as:
ν2,r(m)=Σr=0m└(m−r)(2f1−fO)+r(2f2−fO)┘ (5d)
For the first roundtrip, m=M=1, for r=0 gives ν2,1(1)=(2f1−fo) and for r=1 gives ν2,2(1)=(2f2−fO), i.e. P=2 distinct frequencies. For the second pass, M=2, there are 4 more components: ν2,1(2)=2(2f1−fO), ν2,4(2)=2(2f2−fO) and two components of νhd 2,2(2)=ν2,3(2)=(2f1−fO)+(2f2−fO) i.e. three more distinct frequencies. For the third pass, M=3, there are 8 components: ν2,1(3)=3(2f1−fO), ν2,8(3)=3(2f2−fO), three components ν2,2(3)=ν2,3(3)=ν2,4(3)=2(2f1−fO)+(2f1−fO), and three more components ν2,5(3)=ν2,6(3)=ν2,7(3)=(2f1−fO)+2(2f1−fO) i.e. 4 more distinct frequencies only. For a total of M=3, there are 2+4+8=14 components but only 9 distinct frequencies.
Let us consider that the difference of frequency between the excitation of AOMs in the parallel paths in the two arms is δf=40 MHz. Let us also consider 2f1−fO=10 MHz=ΔF through the element 25 of minimum delay and 2f2−fO=2f1fO+δf=ΔF+δF, through a δ delay along the second path in 25b. Let us consider the first channel due to the first circulation in the rings at ν2,1(1)=10 MHz and the second channel due to the circulation through the other parallel path, at ν2,2(1)=2f1−fO+δf=50 MHz. Also, let us assume an optical path difference between the rings of |LR−LO|=Δ=0.1 mm and the optical delay introduced by a single stair 25 is δ=1 mm The 14 distinct frequencies select signal from 14 depths. Due to the first round-trip, for m=1, two depths are selected: Δ and Δ+δ, for the second round-trip, for m=2, 2Δ, 2(Δ+δ) and 2Δ+δ, for the 3rd round, m=3, 3Δ, 3Δ+δ, 3Δ+2δ, 3Δ+3δ and for a fourth round, m=4, 4Δ, 4Δ+δ, 4Δ+267 , 4Δ+3δ and 4Δ+4δ.
The depths selected from the object correspond to the following optical path differences: mΔ, m(Δ+δ), rΔ+(m−r)(Δ+δ), with m=1 to 4 and r=1 to 4. These can be expressed as:
z
2,r
(m)
=s
1
d
1
+s
2
d
2 (5e)
where for m=1, (1,0), (0,1). For m=2, (2,0), (1,10), (0,2). For m=3, (3,0), (2,1), (1,2), (0,3). For m=4, (4,0), (3,1), (2,2), (1,3), (0,4) These determine 14 distinct OPD values, i.e. selecting 14 distinct axial positions in the object from d1=Δ=0.1 mm to 4d2=3(Δ+δ)=4.4 mm with 12 intermediate steps.
These combinations are illustrated in
d shows in diagrammatic form, another version of the fourth embodiment of the apparatus according to the invention. This is similar to that in
OPD+mΔ=0, where |DR−DS|=Δ (6a,b)
Some of the light, travelling both multiple source paths and multiple reference paths, of lengths: m(DR+DS) is lost, as such lengths are much longer than the main object path. Although power goes into multiple paths outside coherence, this is not essential as long as the power to the object 69 is sufficiently strong, up to the safety level. This means that the losses in the object arm are eliminated as an improvement to the embodiments in the application US2011/0109911. As a second advantage, both the reference and object arms share the same noise source.
If power to the object 69 is not limited by safety, then the present embodiment exhibits less noise for the same achievable signal from a given depth.
An alternative is to use a powerful optical amplifier 33′, in which case source 11 is not necessary.
Optical source 11 can also be narrowband and tunable (swept source), in which case the embodiments in
As another alternative for spectral OCT, the photodetector unit 9, this can use a spectrometer, or two spectrometers in balanced detection, driven by the second splitter 8, as described in “Fourier domain optical coherence tomography system with balance detection”, by A. Bradu and A. Gh. Podoleanu, published in Opt. Express, 2012, 30 Jul. 2012, Vol. 20, No. 16, 17522-17538. In this case, the optical source is broadband.
The frequency shifters, used throughout the invention, in different embodiments, can advantageously be used to eliminate the mirror terms when the optical source 1 is a tunable source and the embodiments operate in spectral domain OCT.
Frequency shifting in the embodiments above can be combined with principles of swept source OCT. Let us say that in the embodiments above, subject so far to broadband illumination, Δλ, data is provided in large steps, d (determined for instance by large delays in 25a), much larger than the coherence length, lc (determined by λ2/Δλ). Then, if the source 1 is changed to a swept source of line-width δλ, sufficiently small to determine a swept source interferometry depth range of at least d/2. A-scans can be assembled for axial range intervals between positions separated by d. With a tuning bandwidth Δλ in the range of tens of nm, for a central wavelength of microns or submicrons, δλ should be a fraction of a nm. By sweeping the optical frequency of the source, signals at the carrier frequencies νm are generated, deviated to lower or higher values depending on the OPD value and its sign. All these carrier frequencies are present in the photodetected signal output of 9. Each resulting channel signal represents a swept source interference signal. FFT of the resulting signals, according to means known in the art, leads to an A-scan in each channel. These A-scans can be used to extend the axial distance for as long as the coherence length of the sweeping source is either side of the OPD=md values. An example of such interrogation in a multiple path interferometry configuration was communicated in the paper “Extra long imaging range swept source optical coherence tomography using re-circulation loops”, published in Opt. Express 18, 25361-25370 (2010), by A. Bradu, L. Neagu, A. Podoleanu.
Further advantage to the prior art, obtained by driving the embodiments presented with a swept source is obtained in ensuring a constant sensitivity with axial depth in swept ource (SS)-OCT. By using P=2 signals only in
where Δk is the tuning bandwidth in wave-number and γ is the scanning rate in Hz. The coefficient C is determined by the swept source, i.e. by its scanning speed and tuning bandwidth. The larger the tuning bandwidth, Δk and the scanning speed, γ, the larger the frequency f generated, i.e. the number of cycles in the photo-detected signal for a given OPD value. Let us consider only two carrier frequencies, ν1 and ν2, applied to the embodiment in
where the second frequency creates what is called a mirror image.
The second channel is created by a carrier ν2 created in a multiplexer 2b by traversing a large delay, δ, leading to frequencies:
When OPD increases, it can be noticed that frequency given by (8a) increases as well as the mirror frequency (9b). However, the strength of the first diminishes, while the strength of the second enhances, as for the first the OPD becomes larger while for the second, δ-OPD becomes smaller. Therefore, the variation of intensity with OPD can be eliminated by putting together the two signals. This becomes possible if:
which leads to:
where
defines the scanning rate of the swept source (Hz/mm) Equation (11) shows that if the difference of the two carrier frequencies is matched to the delay δ, then SS-OCT investigation is possible with constant sensitivity. A similar principle of operation can be implemented here using the frequency shifting in the other embodiments, in
The same type of adjustment is also possible when using spectrometers in 9, and using a broadband source 1.
The embodiments above can be used for despeckle. The multiple phase elements in 25a can be adjusted to produce fractions of 2π differences, while each exhibits the same length. The decoder 91 provides a number of P signals, slightly shifted in phase. After rectification, they can be all superposed to wash out the speckle.
In microscopy, improvement of transversal resolution is achieved by illuminating the target with different phase shifted grids. Such a principle is explained in the article “Method of obtaining optical sectioning by using structured light in a conventional microscope”, by M. A. A. Neil, R. Ju{hacek over ( )}skaitis, and T. Wilson, published in Optics Letters, Vol 22., pp, 1905-1907, (1997). Such grids are created using patterns or diffraction gratings. The procedure requires shifting the grid laterally or rotation of the grid. By doing so, the resolutions along lateral and axial directions improve by a factor of 2. Alternatively, if interference is used, no such physical grid is necessary. If scanning is employed, by switching the reference beam off and on, an equivalent grid is created, as described in “Structured interference optical coherence tomography” by Ji Yi, Qing Wei, Hao F Zhang, and Vadim Backman published in Optics Letters, 37/15, 2048 3050, 2012. In this paper, spectral OCT was used, and each B-scan was composed of 256 A lines, with a B-scan rate of 10 frames/s. For a 250 μm scanning range, each A-scan occupied a 1 μm. Let us say that the transversal resolution in the image is 9 μm. Let us establish a grid of periodicity close to this value, of 12 μm. In this case, 250/12˜21=N bars over the image will be created. By making the number N non integer, the grid varies over the image and the desired phase change is obtained automatically, as described in the paper by M. A. A. Neil above. The disadvantage of the method is that requires collection of at least 3 frames. Leaving the variation of the grid non synchronous with the transversal scanning, requires collection of more than 3 frames. In the paper by Yi, 10 frames were collected. This takes time. The embodiment in
The optical source 1 is swept source, or is broadband and the photodetector unit 9 is replaced with a spectrometer. Let is say that according to the theory, 3 frames are needed of spectral OCT images, at 2π/3 phase interval apart. In this case, the two drivers 64a and 64b are driven with P=3 signals of different frequency and the embodiment in
where Ip are the images collected for a phase step in 25a. Other formulae may be used as explained in the theory of structured light microscopy, based on a sequence of Fourier transformations. In general, more channels can be used, in which case, for P channels, P signals are applied to the AOMs 23 and 24 at different excitation frequencies (40, 80 MHz, etc). They are all switched on and off at the same frequency Fon/off as above (210 Hz), but at different moments within the 1/Fon/off period, shifted in phase between a channel to the next by 1/(P Fon/off). These signals switch the P signals driven by drivers 64a and 64b on and off. All P signals output by 64a and 64b are toggled on and off at the same frequency, Fon/off but with a phase difference for each channel to create a shifted grid in the final image. Several such grids, for different phases are photodetected simultaneously and processed by 91. Combining them according to principles of structured light microscopy leads to improvement of the transversal resolution along the lateral coordinate in the image by a factor of up to 2.
In this case the optical source 1 is broadband. Both laterals scanners in 67 are driven for instance the line scanner with a 500 Hz ramp and the frame scanner with a 2 Hz ramp. Using the same N=21 as in the example above, Fon/off˜10.5 kHz.
Further functionality is achievable in this regime, by taking advantage of the two scanners in 67. Normally, in structured light illumination, the grid is rotated in order to improve the resolution along similar direction in transversal section. As the grid is here created in the interference signals, two possibilities are proposed in this disclosure.
(i) Utilization of the two scanners in 67 to create fast line scans oriented at different angles than in a simple raster operation. In a simplest and widely used raster scanning, a scanner is ran fast, at a line rate to provide the line in the raster and the other scanner is ran slow to provide the frame. In such conventional raster, the lines are oriented horizontally.
Here, both scanners are ran at similar speeds to create a raster where the lines in the raster are oriented parallel, but all at a different angle than the horizontal, angle depending on the control of the two scanners in the pair 67. In this way, in the same area of a conventional raster, the optical beam is deflected over directions different from the horizontal. The improvement in the lateral resolution will take place in the direction of the line. By changing the orientation of the lines in sequentially generated rasters, images are collected with improved resolution, using the reference beam being chopped on and off using the AOMs driven by 64 and 64b at Fon/off.
(ii) Utilisation of the sampling function created in en-face OCT, as presented in “Coherence Imaging by Use of a Newton Rings Sampling Function”, published by A. Gh. Podoleanu G. M. Dobre, D. J. Webb, D. A. Jackson, in Optics Letters, Vol. 21, pp. 1789-1791, (1996) and in “En-face Coherence Imaging Using Galvanometer Scanner Modulation” published by A. Gh. Podoleanu G. M. Dobre, D. A. Jackson in Opt. Letters, vol. 23, pp. 147-149, (1998). By shifting the incident beam away from the pivot of one or both galvanoscanner mirrors in the XY scanner 67, different periodicity of the sampling function can be achieved. The sampling function mentioned in these two articles, in the form of Newton rings and respectively grid of lines can be employed to take over the function of the grid projected over the target in conventional structured light microscopy. The orientation of such a grid in the final en-face OCT image changes depending on the orientation of the mirror used as target. The three phase shifts, as a minimum, necessary for structured light demodulation, require a change in phase in the reference path of ⅓ of wavelength. The multiple phase element 25b in the embodiment in
Obviously, for switching off the P carriers, at least one of the carrier in the pairs of signals applied to the AOMs 23 and 24 can be used and not both.
In the PCT application WO/2009/106884A1 and UKPO, 0803559.4, by Podoleanu, the depth was encoded on the frequency shift imprinted by the number of wave passages through frequency shifters. This limited the applicability of the configurations disclosed, as such modulators are dispersive, lossy, and therefore require optical amplification. Addition of extra components make the roundtrip length larger than 10 cm, ie small roundtrips are not possible. In the embodiment in
In the reference path, a third splitter, 29, conveys light towards a reference mirror 63 used to adjust the OPD in the interferometer. This third splitter can be eliminated and have the reference path in transmission as in the embodiments in
Interference will take place for OPD values satisfying equation, OPD+mA=0, where OPD is measured along the main paths of the interferometer, up to a mirror or the surface of the the object, 69, and Δ is the OPD between the lengths of the two rings 44 and 44′. If significant strength signal can be acquired for m=M roundtrips through the two rings 44 and 44′, then M depths can be interrogated in a time T=Mτ, covering an axial range L=MΔ. For instance, for M=100, with T=10 ns, T=1μs. The differential path length Δ, between the two rings can be adjusted from small values, let us say 10 μm, as required in OCT tissue measurements, up to 1 mm, as required in tracking the axial position of a reflector within a large range of 100 mm, or for optical time domain (OTDR) applications. In these examples, the bandwidth of the optical source 1 has to be large enough to determine a coherence length of approximately 10 μm in OCT applications and approximately 1 mm for OTDR applications. All the numerical values in the examples above are attainable with the current technology.
In prior art implementations, dispersion of long fiber links prevented considering interference principles to be applied to OTDR instrumentation. In
Two pulses at least per pulse in the photodetected signal requires a frequency difference between the object and reference wave of at least 200 MHz for τ=10 ns. This however can be scaled to τ=100 ns, in which case 20 MHz difference may suffice, and a round trip τ=100 ns would require a decent fibre length in each loop of 20 m.
b shows the theoretical power output from a ring 44, based on a single coupler design for two values of the cross coupling ratio relative to the power of the input pulse, left: 10% and right: 1% . The figures also show that the first pulse coming out of the ring 44 has a large power, close to the input pulse power. As conservation of power among multiple roundtrips requires power redistribution among the multiple pulses, a large pulse power is required for the optical source 1. The first pulse therefore, may damage the subsequent optical components. In order to protect the optical amplifiers 33 and 33′ in
The problem of the first pulse being sent to the two interferometer arms can be addressed by using delay lines as shown in the embodiment in
As the duration of the pulse, τs, is set to be less than the roundtrip time of the loop, τ, the loop will ‘output’ a series of pulses of decreasing amplitudes, where the decrease is approximately only 2%, of duration equal to the original pulse length and repeated at a period equal to the roundtrip time of the loop. In this way, the attenuation of power from a roundtrip to the next is reduced to less than 10 log(1/0.98)=0.08 dB, much smaller than 4 dB, the best result achieved with rings using optical amplifications and frequency shifters in L. Neagu, A. Bradu, L. Ma, J. W. Bloor and A. Gh. Podoleanu in Optics Letters Vol. 35, No. 13/Jul. 1, 2010, pp. 2296-2298. As there is no initial strong pulse, no toggle of the AOMs 23 and 23′ is needed, and therefore the two drivers 64 and 64′ operate continuously.
The embodiments in
AOMs 23 and 23′ by respective drivers 64 and 64′. Alternatively, only one AOM of high frequency can be used with a second device of similar material placed in the other interferometer arm for dispersion compensation. If femtosecond sources are used, then stretchers should be utilized to increase the pulse width τs to more than 2/carrier frequency.
The AOMs 23 and 23′ are driven by single frequency drivers 64 and 64′, excited at FO and FR respectively. For demodulation, the decoder uses a mixer 72a that creates the sum (or the difference) of FR and FO as input to mixer 72b, to serve the demodulation of pulses after the balanced photodetector 9.
In effect, time determination of the interference with respect to the first pulse from the source 1 is used to infer the number of roundtrips in the two rings. In this way, the axial position of the scattering point in 69, or if the embodiment is used for tracking, the axial position of the reflector 69 can be determined The differential delay A between the OPDs in these rings 34 and 34′ determine the separation of sampling positions of the axial position of a mirror 69. For this method, OTDR is used to determine the circulation number, m, while the resolution in the measurement continues to be given by the coherence length of the optical source 1. The circulation number is determined temporally comparing the time of output pulses from 9 with the pulse from optical source 1, using meaning known in the art, such as START/STOP circuits.
As a difference to conventional OTDR, the sampling resolution is determined by the inverse of the optical spectrum width (coherence length), and not by the pulse length. Another difference with conventional OTDR is that if interference is to be used for detection, the source needs to be coherent with a coherence length larger than the axial range. Here, a broadband source is used and the axial range is determined by the number of roundtrips.
a shows in diagrammatic form, an eighth embodiment of the apparatus according to the invention, based on multiplexers as disclosed in
b shows in diagrammatic form, the succession of interference wave trains output of the embodiment in
ν11=F23−F23′+F24−F24′ and ν21=F23+δf−F23′+F24+δf−F24=ν11+δf (12a,b)
where F23′=F24′. The embodiment in
a shows an embodiment, where a multiplexer of type 2j, is placed in the object arm. The frequency shifter, 23′, drives an implementation of the multiple phase elements 25d, based on an optical ring. After each round trip, a new phase change takes place, similar with using several phase elements, however this takes place here sequentially. A first application of such multiple phase elements 25 is in providing stepped delays. Each is interrogated by a different optical frequency due to chirping the frequency of the signal applied to the frequency shifter 23′. Such a modulation technique represents a variant of frequency modulation continuous wave (FMCW) method. FMCW has traditionally been developed around a laser source, whose frequency is chirped. Beating of the local optical signal with the received signal, after traveling an optical path, leads to a beat signal whose frequency is proportional to the optical path length. The frequency beat is due to the instantaneous difference in the chirped frequencies of the two signals. FMCW is used here to determine the number of roundtrips before interference. The frequency shifting is performed again, outside the multiple delays, using rings 34 and 34′ and low cross coupling efficiency directional couplers 35, 36, 35′ and 36′. Here, FMCW is combined with recirculating delay lines and low coherence interferometry. In the bottom path, the object arm, the multiple delay line is between two AOMs, operating as frequency shifters, 23′ and 24′. In the reference arm, a third frequency shifter, 23, is mounted between the circulator 29 and a mirror 63, so light travels twice through 23 and incurs a double frequency shift.
Here the driver 64, delivers a single signal, of frequency FR, to the AOM 23, while the drivers, 74 and 74′ of the AOM 23′ and 24′ respectively produce a ramp variation of the frequency of their exciting signal. They are controlled in synchronism, provided by a pulse generator 92. A pulse generator 92 triggers the chirping of the two oscillator drivers 64 and 64′ determined by two frequency sweep drivers 74 and 74′. Both AOM 23′ and 24′ shift the optical frequency in the same direction, either up or down. The upper graph in
Key factors of such an embodiment are:
The sampling resolution is determined by the bandwidth of the broadband optical source 1;
The step size between sampling positions is determined by the difference in the optical path lengths of the loops, 34 and 34′, Δ, in the object and reference paths;
Let us say that the frequency shift of the optical signals at the output of the AOMs varies between fmin and fmax and the frequency shift due to the frequency shifter 23 in the reference arm is 2FR. The frequency shift of the optical signal at the output of the first AOM, 23′, is:
F
1
=f
min+(t/T)(fmax−fmin) (13)
and for the optical signal at the output of the second AOM, 24′, is:
F
2
=f
max−[(t+mτ)/T](fmax−fmin) (14)
In order to ensure a large carrier frequency, the AOM 23 is driven in antiphase to the two AOMs, 23′ and 24′, and the photodetected signal at the output of 9 pulsates at a frequency:
ν=F1+F2+2FR (15)
For instance, such adjustment can be achieved when the frequency of the output waves of the AOM 23′ and 24′ is shifted up and the frequency of the AOM 23 is shifted down. Waves with different delay, mτ, originate at the output of the delay line 34. As the two AOMs 23′ and 24′ are excited in synchronism, for each time interval, multiple of the roundtrip τ, the overall frequency shift of the signal at the output of the second AOM, 24′, will differ, depending on the phase shift introduced by the roundtrips in the delay line 34.
By beating signal at different time intervals, a different frequency is obtained at the output of balance detector 9. At coherence, the photodetected signal pulsates at a frequency:
νm=fmin+fmax+2Fr−(mτ/T)(fmax−fmin) (16)
The minimum frequency of the signal output is obtained for the direct transfer of the wave:
νmin=fmin+fmax+2FR (17)
After m=M roundtrips, Mτ=T, the frequency bit v reaches the maximum:
νmax=fmin+fmax+2FR+fmax−fmin=2fmax+2FR (18a,b)
As example, let us say that fmin=40 MHz, fmax=60 MHz and FR=40 MHz. Then, νmin=180 MHz and νmax=200 MHz. A difference νmax−νmin=20 MHz is utilized to code the number of roundtrips, m. A minimum duration of interaction of 2 cycles in the period 1/νmin=7.14 ns, requires a roundtrip of at least 2/νmin=14 ns. With a bandwidth, B, of 1 MHz in continuous wave (CW) required for en-face OCT imaging, then the number of channels is:
(νmax−νmin)/B=M=20 (19a,b)
channels. This requires a period T=Mτ=207 ns=0.14 μs.
Let us say that the reference signal, shifted in frequency by 2FR, travels along the reference path of length LR. This will interfere with the optical signal in the object arm shifted in frequency by fmin+fmax, travelling up to the top of the object, along object length LO.
Let us assume that the length of the ring 34, lR, in the reference path is longer than the length of the ring 34′, lO in the object path by, Δ. For an object of index of refraction n, this means that the coherence gate selects signal from a depth z given by:
L
O+2nz=LR+mΔ (20)
ie from depths z in the object 69 at:
z=mΔ/(2n)+(LR−LO)/(2n) (21)
Let us say that the reference path is adjusted to LR=LO, where LO is the object path up to the top of the object, 69. This gives:
z=mΔ/(2n) (22)
M depths in the object can be interrogated this way, where MΔ defines the axial range of the method. Each depth, zm, is encoded on a frequency νm. The top of the object is encoded on the beat frequency νmin=180 MHz.
So the frequency is chirped in M steps from fmin to fmax and the OPD range is MΔ.
For the embodiment to work, it is required that the differential path length between the two rings 34 and 34′, Δ, is larger than the axial resolution, lc/2, where lc is the coherence length determined by the optical source bandwidth, evaluated in the object 69 (ie after correction for its index of refraction).
Signal for each en-face image is provided in a time τ out of T. Such an embodiment allows scanning in depth an axial range MΔ without any mechanical means. The speed of scanning is 1/T, which, with the numerical example above exceeds 200 kHz. While such A-scan speeds are available now with spectral domain OCT, the embodiment and method disclosed here is scalabale in range to much larger axial ranges than achievable with spectral domain OCT. For instance, Δ can be set to 1 mm, achieving an A-scan with M=20 points from an axial range of MΔ=2 cm. Each channel in depth is encoded in frequency, determined by the difference in the instantaneous chirps between the two AOMs, 23′ and 24′.
If a value T, 10 times larger than that above is used, of 4 μs, M becomes 10 times larger, 200 on the expense of the bandwidth B, according to (12a), reduced to 100 kHz. The signal for each channel continues to be produced in a time interval τ only out of the total T. Due to this peculiarity, the optical source 1 can be a pulse and not a CW source, emitting pulses at a repetition rate T and of τ duration. Obviously, the repetition period may be larger than T, if safety reasons requires this. Synchronism needs to be secured between pulse emission and start of the waveforms in
Obviously, the AOM 23 could have been placed in any other place along the reference path. Also, the multiplexer 2 could have been placed in the reference arm instead and a third AOM driven at a fixed frequency, in the object arm.
Another embodiment according to the invention is disclosed in
The frequency of the optical signal at the output of the first AOM, 23′, is shifted up by:
F
1
=f
min+(t/T)(fmax−fmin) (23)
and the optical signal at the output of the AOM 23 is shifted up by:
F
2
=f
min+[(t+mτ)/T](fmax−fmin) (24)
As the two AOMs 23′ and 24′ are excited in synchronism, for each round trip through the two rings 34 and 34′, a multiple MT delay will accumulate, so the overall frequency shift of the interference signal after 9 will differ, depending on the number of roundtrips, m:
νm=F2−F1=fmax−fmin+(mτ/T)(fmax−fmin) (25)
After m=M roundtrips, Mτ=T, the frequency bit v reaches the maximum:
νM=2(fmax−fmin) (26)
As example, let us say that fmin=40 MHz, fmax=60 MHz. Then, vmin=20 MHz and νmax=40 MHz. A difference νmax−νmin=20 MHz is utilized to code the number of roundtrips, m. A minimum duration of interaction of 2 cycles in the period 1/νmin=50 ns, requires a roundtrip of at least 2/νmin=100 ns. With a bandwidth, B, of 1 MHz in CW required for en-face OCT imaging, then (νmax−νmin)/B=M=20 channels. This requires a period T=Mτ=20 100 ns=2 μs.
Let us consider an application, where the object 69 is a mirror and the embodiments in
As mentioned above, the difference path between the multiple paths in the rings, A, can be made much larger than the coherence length, lc, of the broadband optical source 1, in which case the embodiments above in
The axial resolution is now determined by the tuning range Δλ. Using principles of swept source interferometry, multiple A-scans can be generated, replicated by the number M of multiple delay channels in the embodiments presented. Let us say that as in the numerical example above in connection with
The foregoing description has been presented for the sake of illustration and description only. As such, it is not intended to be exhaustive or to limit the invention to the precise form disclosed. For example, reference was primarily made to measurements and imaging in reflection, however measurements and imaging in transmission could equally be performed. Several examples have been given on using the multipath interferometer configuration in time domain OCT and spectral domain OCT. These are not exhaustive, have been presented as a matter of example and modifications and variations are possible in light of the above teaching which are considered to be within the scope of the present invention. Thus, it is to be understood that the claims appended hereto are intended to cover such modifications and variations, which fall within the true scope of the invention.
For instance, the optical source 11 in the optical source block, 1, can be any of broadband or tunable narrow band optical source, a semiconductor amplifier or a fiber amplifier.
In the embodiments above, where simultaneous multiple path interrogation was meant, this may also refer to multiple flow measurements. Displacement speed values of liquids inside vessels and pipes can be deteremined simultaneously, where the multiple channels can be used to sample the flow at different depths inside the vessel diameter. The optical source 1 can be broadband or narrow tunable, leading to a different signal frequency in each channel depending on the local speed inside the vessel at the depth interrogated.
Other modifications and alterations may be used in the design and manufacture of the apparatus of the present invention and in the application of the methods disclosed without departing from the spirit and scope of the accompanying claims.
Variations include the grouping of recirculation optical loops with a main loop, via a splitter or two splitters where some of the elements are placed in the shared path between the recirculation loop and the main loop.
Variations may also include the grouping of optical devices in the recirculating loops, such as optical modulators (at least one of the following: frequency shifter, amplitude modulator, phase modulator, polarization modulator, spectral scanning delay line) with optical amplifiers.
The optical source can be pulsed with pulses of width less or larger than the recirculating time of the optical wave through each of the recirculation loop. The optical source may also be continuous, operating in CW regime.
Variations may also include the operation of the invention in sensing or OCT imaging.
Variations include the photodetection unit, which may consist of at least one photodetector, and/or two photodetectors whose electrical signals are subtracted one from the other in a balance detection configuration. A spectrometer, or two spectrometers in balance configuration can be used, in case spectral OCT principles are implemented in those embodiments.
Frequency shifters have been mentioned, as acoustooptic modulators, other means can be used, such as in-fibre frequency shifters, or moving mirrors, or fluids, or spectral scanning delay lines, using a diffraction grating and a scanning mirror as exemplified in the patent “Transmissive scanning delay line for optical coherence tomography”, U.S. Pat. No. 7,417,741.
It should be also obvious for those skilled in the art, that the desired frequency shifting may be achieved by using either a single frequency shifter or several frequency shifters. The later is preferred to compensate for the dispersion in the two interferometer arms. Difference or summation of the frequency shifts can be employed by choosing frequency shifting up or down when constructing the acousto-optic modulators. Selection of the difference of frequencies, |FO−FR| is preferred for allowing the photodetector unit 9 work on lower frequency values. In some applications it may be desirable to operate on the sum of the two frequencies, with ΔF=FO+FR, to ensure a sufficiently number of oscillating periods within a limited pulse-width pulse when working in pulses.
The object may be considered as a succession of sensing points that each needs interrogation. Using principles disclosed here, these sensors could be interrogated sequentially or in parallel by using multiple delays to match the position in the object of each such sensor.
Optical delays can be implemented in several ways known in the art. Multiple phase delay elements can include an array of different refractive index elements or an array of active optical elements where the index of refraction can be actively controlled.
Number | Date | Country | Kind |
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GB 1216332.5 | Sep 2012 | GB | national |