Multiplex polony genotyping

Information

• Research Project
• 6689866

• ApplicationId

  6689866

• Core Project Number

  R43HG002971

• Full Project Number

  1R43HG002971-01

• Serial Number

  2971

• FOA Number

• Sub Project Id

• Project Start Date

  9/30/2003 - 20 years ago

• Project End Date

  3/29/2004 - 20 years ago

• Program Officer Name

  SCHLOSS, JEFFERY

• Budget Start Date

  9/30/2003 - 20 years ago

• Budget End Date

  3/29/2004 - 20 years ago

• Fiscal Year

  2003

• Support Year

  1

• Suffix

• Award Notice Date

  9/26/2003 - 20 years ago

Organizations

• Agencourt Bioscience Corporation

(Revised Abstract) Description: The ascertainment of millions of SNPs in the human genome, characterization of haplotype blocks and development of improved SNP-based linkage panels has fueled the need for accurate, efficient, and low cost SNP genotyping technologies to support genetic inheritance and disease association studies. The overall goals of this proposal are to develop and test a novel method for multiplex genotyping using in-gel polony amplification and fluorescence in situ sequencing. In Phase I, the core genotyping technology will be tested using a set 372 SNPs from The SNP Consortium (TSC) linkage panel with known genotypes on individuals from the CEPH families. Genotypic data will be collected from 48 unrelated CEPH individuals and evaluated in terms of success rate and accuracy. The cost competitiveness of the technology relative to other established genotyping technologies will then be evaluated.

IC Name

• Activity

  R43

• Administering IC

  HG

• Application Type

  1

• Direct Cost Amount

• Indirect Cost Amount

• Total Cost

  117939

• Sub Project Total Cost

• ARRA Funded

• CFDA Code

  172

• Ed Inst. Type

• Funding ICs

  NHGRI:117939\

• Funding Mechanism

• Study Section

  ZRG1

• Study Section Name

  Special Emphasis Panel

• Organization Name

  AGENCOURT BIOSCIENCE CORPORATION

• Organization Department

• Organization DUNS

• Organization City

  BEVERLY

• Organization State

  MA

• Organization Country

  UNITED STATES

• Organization Zip Code

  01915

• Organization District

  UNITED STATES