Claims
- 1. A compound selected from the group having the formula: ##STR52## wherein; n is selected from zero, one or two;
- A.sup.1 and A.sup.2 are selected from straight or branched-chain alkalenes having 1 to 8 carbon atoms and p and d are selected from zero or one with the proviso that when the --(A.sup.1).sub.p --X--(A.sup.2).sub.d --Q radical is in the 2-position, p is at least one;
- X is selected from --S--, --S(O)-- or --S(O).sub.2 --;
- Q is selected from
- (1) 1 or 2-naphthyl,
- (2) 2,3-dihydro-1H-inden-4-yl or 2,3-dihydro-1H-inden-5-yl,
- (3) biphenyl,
- (4) phenyl,
- (5) ##STR53## wherein R.sup.3 is selected from fluorine, chlorine, bromine, iodine, loweralkyl (1-8 carbons), loweralkoxy (1-8 carbons), trifluoromethyl, hydroxy, cyano or nitro, R.sup.4 is selected from hydrogen, fluorine, chlorine, bromine, iodine, methyl, ethyl, isopropyl, methoxy, ethoxy and nitro and R.sup.5 is selected from hydrogen, methyl, ethyl, methoxy, ethoxy, methylthio and phenylthio,
- (6) ##STR54## wherein R.sup.6 is selected from --NR.sup.7 R.sup.8, --C(O)NR.sup.7 R.sup.8, --(CH.sub.2).sub.b NR.sup.7 R.sup.8, --B--(CH.sub.2).sub.b NR.sup.7 R.sup.8 or --B--(CH.sub.2).sub.b OR.sup.7 wherein B is selected from --O--, --S--, --S(O)-- or --S(O).sub.2 --, b is 2 or 3 and R.sup.7 and R.sup.8 are selected from hydrogen, loweralkyl (1-8 carbons) and may be the same or different,
- (7) ##STR55## wherein R.sup.9 is selected from --SR.sup.10, --S(O)R.sup.10 and --S(O.sub.2)R.sup.10 wherein R.sup.10 is selected from loweralkyl (1-8 carbons) and phenyl with the proviso that X must be --S(O).sub.2 --, or,
- (8) ##STR56## wherein A.sup.3 is selected from straight or branched-chain alkalenes (2-8 carbons) and G is selected from loweralkoxy (1-8 carbons) or --NR.sup.11 R.sup.12 wherein R.sup.11 and R.sup.12 are selected from hydrogen, loweralkyl (1-8 carbons), phenyl and phenyl-loweralkyl, (7-14 carbons) and may be the same or different, and the acid addition salts and hydrates thereof.
- 2. The compound of claim 1 which is 3-[(4-chlorophenyl)thio]pyrrolidine or an acid addition salt thereof.
- 3. The compound of claim 1 which is 3-[(4-chlorophenyl)sulfinyl]pyrrolidine or an acid addition salt thereof.
- 4. The compound of claim 1 which is 3-[(4-chlorophenyl)sulfonyl]pyrrolidine or an acid addition salt thereof.
- 5. The compound of claim 1 which is 3-(phenylsulfonyl)pyrrolidine or an acid addition salt thereof.
- 6. The compound of claim 1 which is 3-[(4-methoxyphenyl)sulfonyl]pyrrolidine or an acid addition salt thereof.
- 7. The compound of claim 1 which is 3-[(4-methylphenyl)thio]pyrrolidine or an acid addition salt thereof.
- 8. The compound of claim 1 which is 3-[(4-methylphenyl)sulfonyl]pyrrolidine or an acid addition salt thereof.
- 9. The compound of claim 1 which is 3-[(3,4-dichlorophenyl)sulfonyl]pyrrolidine or an acid addition salt thereof.
- 10. The compound of claim 1 which is 3-[(3,4-dichlorophenyl)thio]pyrrolidine or an acid addition salt thereof.
- 11. The compound of claim 1 which is 3-[(3-chlorophenyl)thio]piperidine or an acid addition salt thereof.
- 12. The compound of claim 1 which is 3-[(4-chlorophenyl)thio]piperidine or an acid addition salt thereof.
- 13. The compound of claim 1 which is 3-[(4-chlorophenyl)sulfonyl]piperidine or an acid addition salt thereof.
- 14. The compound of claim 1 which is 3-(phenylsulfonyl)piperidine or an acid addition salt thereof.
- 15. The compound of claim 1 which is 3-[(4-chlorophenyl)sulfinyl]piperidine or an acid addition salt thereof.
- 16. The compound of claim 1 which is 3-[(3-chlorophenyl)sulfonyl]piperidine or an acid addition salt thereof.
- 17. The compound of claim 1 which is 3-[(4-methylphenyl)sulfonyl]piperidine or an acid addition salt thereof.
- 18. The compound of claim 1 which is 3-[(4-fluorophenyl)sulfonyl]piperidine or an acid addition salt thereof.
- 19. The compound of claim 1 which is 3-[(4-methoxyphenyl)sulfonyl]piperidine or an acid addition salt thereof.
- 20. The compound of claim 1 which is 4-[(4-chlorophenyl)thio]piperidine or an acid addition salt thereof.
- 21. The compound of claim 1 which is 4-[(4-chlorophenyl)sulfonyl]piperidine or an acid addition salt thereof.
- 22. The compound of claim 1 which is 4-[(4-chlorophenyl)sulfinyl]piperidine or an acid addition salt thereof.
- 23. The compound of claim 1 which is N,N-dimethyl-2-[4-[(3-piperidinyl)sulfonyl]phenoxy]ethanamine or an acid addition salt thereof.
- 24. The compound of claim 1 which is N,N-diethyl-2-[4-[(3-piperidinyl)sulfonyl]phenoxy]ethanamine or an acid addition salt thereof.
- 25. The compound of claim 1 which is 3-[[4-(2-methoxyethoxy)phenyl]sulfonyl]piperidine or an acid addition salt thereof.
- 26. The compound of claim 1 which is 3-[(phenylsulfonyl)methyl]piperidine or an acid addition salt thereof.
- 27. The compound of claim 1 which is 2-[[(4-chlorophenyl)sulfonyl]methyl]piperidine or an acid addition salt thereof.
- 28. The compound of claim 1 which is 4-[(4-methoxyphenyl)sulfonyl]piperidine or an acid addition salt thereof.
- 29. The compound of claim 1 which is 4-[(2,5-dichlorophenyl)thio]piperidine or an acid addition salt thereof.
- 30. The compound of claim 1 which is 4-methylphenyl)thio]piperidine or an acid addition salt thereof.
- 31. The compound of claim 1 which is 4-(phenylthio)piperidine or an acid addition salt thereof.
- 32. The compound of claim 1 which is 4-[(2-chlorophenyl)thio]piperidine or an acid addition salt thereof.
- 33. The compound of claim 1 which is 4-[(3-chlorophenyl)thio]piperidine or an acid addition salt thereof.
- 34. The compound of claim 1 which is 4-[(3,4-dichlorophenyl)thio]piperidine or an acid addition salt thereof.
- 35. The compound of claim 1 which is 3-[(2-chlorophenyl)thio]piperidine or an acid addition salt thereof.
- 36. The compound of claim 1 which is 4-[(4-fluorophenyl)thio]piperidine or an acid addition salt thereof.
- 37. The compound of claim 1 which is 2-[[(4-chlorophenyl)thio]methyl]piperidine or an acid addition salt thereof.
- 38. The compound of claim 1 which is 4-(phenylsulfinyl)piperidine or an acid addition salt thereof.
- 39. The compound of claim 1 which is 3-[(phenylthio)methyl]piperidine or an acid addition salt thereof.
- 40. The compound of claim 1 which is 3-(phenylthio)piperidine or an acid addition salt thereof.
REFERENCE TO RELATED APPLICATIONS
This application is a continuation-in-part of U.S. application Ser. No. 598,582 filed on Apr. 10, 1984, abandoned.
US Referenced Citations (2)
Number |
Name |
Date |
Kind |
4065584 |
Lafon |
Dec 1977 |
|
4294841 |
Champseix |
Oct 1981 |
|
Continuation in Parts (1)
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Number |
Date |
Country |
Parent |
598582 |
Apr 1984 |
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