Nawwar et al, Collection of Czechoslovak Chemical Communications, vol. 60, No. 12, pp. 2200-2288, 1995.* |
Bengtsson et al, Acta Pharmaceuticla Suecica, vol. 19, No. 1, pp. 37-42, 1982.* |
Howe et al, Journal of Medicinal Chemistry, vol. 15, No. 10, pp. 1040-1045, 1972.* |
Chartier-Harlan, et al. “Early-Onset Alzheimer's Disease Caused by Mutations at the Codon 717 of the β-Amyloid Precursor Protein Gene.” Nature. 353: 844-846 (1989). |
Citron, et al. “Mutation of the β-Amyloid Precursor Protein in Familial Alzheimer's Disease Increases β-Protein Production,” Nature. 360: 672-674 (1992). |
Clark. The Chemistry of Penicillin. Princeton University Press, pp. 240, 708, 786, 795 and 875 (1949). |
Cordell, B. “β-Amyloid Formation as a Potential Therapeutic Target for Alzheimer's Disease.” Annu. Rev. Pharmcol. Toxicol. 34: 69-89 (1994). |
Desai, M.C., et al. “Polymer Bound EDC (P-EDC): A Convenient Reagent for Formation of an Amide Bond.” Tetrahedron Letters. 34(48): 7685-7688 (1993). |
Doherty, et al. “The Resolution of Amino Acids by Asymmetric Enzymatic Synthesis.” J. Biol. Chem. 189: 447-454 (1951). |
Glenner, et al. “Alzheimer's Disease: Initial Report of the Purification and Characterization of a Novel Cerebrovascular Amyloid Protein.” Biochem. Biophys. Res. Commun. 120: 885-890 (1984). |
Goate, et al. “Segregation of a Missense Mutation in the Amyloid Precursor Protein Gene wtih Familial Alzheimer's Disease.” Nature. 349: 704-706 (1990). |
Hansen, et al. “Reexamination and Further Development of a Precise and rapid Dye Method for Measuring Cell Growth/Cell Kill.” J. Immunol. Meth. 119: 203-210 (1989). |
Johnson-Wood, et al. PNAS USA. 94: 1550-1555 (1997). |
Losse, et al. Tetrahedron. 27: 1423-1434 (1971). |
Murrell, et al. “A Mutation in the Amyloid Precursor Protein Associated with Hereditary Alzheimer's Disease.” Science. 254: 97-99 (1991). |
Mullan, et al. “A Pathogenic Mutation for Probably Alzheimer's Disease in the APP Gene at the N-Terminus of β-Amyloid.” Nature Genet. 1:345-247 (1992). |
Ogawa, et al. “A New Method for Preparing D-Penicillamine, Reaction of Benzylpenicilloic Acid α-Amides with Arylamines.” Chem. Pharm. Bull. 36(6): 1957-1962 (1988). |
Pazhanisamy, et al. “β-Lactamase-Catalyzed Aminolysis of Depsipeptides: Peptide Inhibition and a New Kinetic Mechanism.” Biochemistry. 28: 6875-6882 (1989). |
Papadopoulos, et al. “Anodic Oxidation of N-Acyl and N-Alkoxycarbonyl Dipeptide Esters as a Key Step for the Formation of Chiral Heterocyclic Synthetic Building Blocks.” Tetrahedron. 47(4/5): 563-572 (1991). |
Pessina, et al. “Amide-Bond Syntheses Catalyzed by Penicillin Acylase.” Helvetica Chimica Acta. 71: 631-641 (1988). |
Pilotti, et al. Chemical Abstracts. 86(1) 715n, p. 772 (1977). |
Selkoe, D. “Amyloid Protein and Alzheimer's Disease.” Scientific American. 68-78 (1991). |
Selkoe, D. “The Molecular Pathology of Alzheimer's Disease.” Neuron. 6: 487-498 (1991). |
Seubert, P. Nature. 359: 325-327 (1992). |
Smith, et al. “β-APP Processing as a Therpeutic Target for Alzheimer's Disease.” Current Pharmaceutical Design. 3: 439-445 (1997). |
Waldmann, et al. “Selective Enzymatic Removal of Protecting Groups: The Phenylacetamide as Amino Protecting Groups in Phosphopeptide Synthesis.” Tetrahedron Letters. 37(48:8725-8728 (1996). |