N-HA Coated Dental Implant for Accelerated Early Healing

Information

  • Research Project
  • 6787502
  • ApplicationId
    6787502
  • Core Project Number
    R43DE015881
  • Full Project Number
    1R43DE015881-01
  • Serial Number
    15881
  • FOA Number
  • Sub Project Id
  • Project Start Date
    4/1/2004 - 20 years ago
  • Project End Date
    3/31/2005 - 19 years ago
  • Program Officer Name
    HUNZIKER, ROSEMARIE
  • Budget Start Date
    4/1/2004 - 20 years ago
  • Budget End Date
    3/31/2005 - 19 years ago
  • Fiscal Year
    2004
  • Support Year
    1
  • Suffix
  • Award Notice Date
    2/18/2004 - 20 years ago
Organizations

N-HA Coated Dental Implant for Accelerated Early Healing

DESCRIPTION: This SBIR Phase I program is Aimed at demonstrating the feasibility of nano-hydroxyapatite ("n-HA") coated titanium Dental implants, using a novel electrophoretic deposition ("EPD") process. The HA nanocoating with approximately 50nm grain size and microsized porosities will provide higher surface bioactivity and blood coagulation compared to conventional microsized HA coatings without micropores on the surface leading to a significantly faster early-stage bone healing process. The EPD will be used to uniformly coat n-HA into the pores of Ti beaded implants, which the conventional thermal spray process cannot do. This program builds on the previous experience of Inframat in EPD fabricated HA nano-coatings for hip replacement applications in an NIH funded SBIR program and other development projects with corporate partners, demonstrating HA nano-coatings on a non-porous Ti6AI4V substrate having the unique n-HA plus micropores surface texture, 3X increased HA coating to Ti substrate adhesion strength, and 300X enhanced corrosion resistance in-vitro. The proposed program will: 1) optimize n-HA graded composition and EPD parameters, 2) coat n-HA on porous Ti beaded and screw shaped Dental implants, and 3) perform HA nanocoating property evaluations. The developed Dental implant products are expected to outperform the current anodized porous (Ti beaded) and plasma spray HA coated screw Dental implants with the benefits of accelerated early-stage healing and decreased pain for patients.

IC Name
NATIONAL INSTITUTE OF DENTAL &CRANIOFACIAL RESEARCH
  • Activity
    R43
  • Administering IC
    DE
  • Application Type
    1
  • Direct Cost Amount
  • Indirect Cost Amount
  • Total Cost
    99998
  • Sub Project Total Cost
  • ARRA Funded
  • CFDA Code
    121
  • Ed Inst. Type
  • Funding ICs
    NIDCR:99998\
  • Funding Mechanism
  • Study Section
    ZRG1
  • Study Section Name
    Special Emphasis Panel
  • Organization Name
    INFRAMAT CORPORATION
  • Organization Department
  • Organization DUNS
  • Organization City
    FARMINGTON
  • Organization State
    CT
  • Organization Country
    UNITED STATES
  • Organization Zip Code
    060322597
  • Organization District
    UNITED STATES