Claims
- 1. A naphthacene of the formula: ##SPC4##
- wherein one of R.sub.1 and R.sub.2 is oxygen and the other is oxygen or :N - NHR.sub.3, and R.sub.3 is alkanoyl of up to 4 carbon atoms, alkanoyl of up to 4 carbon atoms substituted by a sulphonic acid group, alkanoyl of up to 4 carbon atoms substituted by a quaternary ammonium group, thiocarbamoyl, methylthiocarbamoyl amidino, or benzoyl, and non-toxic salts thereof.
- 2. A naphthacene of the formula: ##SPC5##
- wherein one of R.sub.1 and R.sub.2 is oxygen and the other is oxygen or :N - NHR.sub.3, and R.sub.3 is alkanoyl of up to 4 carbon atom, alkanoyl of up to 4 carbon atoms substituted by a sulphonic acid group, alkanoyl of up to 4 carbon atoms substituted by a quaternary ammonium group, thiocarbamoyl, amidino, or benzoyl, and non-toxic salts thereof.
- 3. The naphthacene derivative according to claim 1 which is 4-methoxy-5- (or 12-) oxo-6,9,11-trihydroxy-7-(2,3,6-O-tridesoxy-3-amino-1-L-lyxohexosyl)-9-[1-(3-sulpho-propionylhydrazono)ethyl]-12- (or 5-) (3-sulpho-propionylhydrazono)-5,7,8,9,10,12-hexahydro-naphthacene, and non-toxic acid addition and non-toxic metal salts thereof.
- 4. The naphthacene derivative according to claim 1 which is 4-methoxy-5- (or 12-) oxo-6,9,11-trihydroxy-7-(2,3,6-O-tridesoxy-3-amino-1-L-lyxohexosyl)-9-[1-(trimethylammonioacetylhydrazono)ethyl]-12- (or 5-) (trimethylammonioacetylhydrazono)-5,7,8,9,10,12-hexahydro naphthacene dichloride, and non-toxic acid addition salts thereof.
- 5. The naphthacene derivatives according to claim 1 which is 4-methoxy-5,12-dioxo-6,9,11-trihydroxy-7-(2,3,6-O-tridesoxy-3-amino-1-L-lyxohexosyl)-9-[1-(thiosemicarbazono)ethyl]-5,7,8,9,10,12-hexahydronaphthacene, and non-toxic acid addition salts thereof.
- 6. The naphthacene derivative according to claim 1 which is 4-methoxy-5,12-dioxo-6,9,11-trihydroxy-7-(2,3,6-O-tridesoxy-3-amino-1-L-lyxohexosyl)-9-[1-(amidinohydrazono)ethyl]-5,7,8,9,10,12-hexahydronaphthacene, and non-toxic addition salts thereof.
- 7. The naphthacene derivative according to claim 1 which is 4-methoxy-5- (or 12-) oxo-6,9,11-trihydroxy-7-(2,3,6-O-tridesoxy-3-amino-1-L-lyxohexosyl)-9-[1-(thiosemicarbazono)ethyl]-12- (or 5-) (thiosemicarbazono)-5,7,8,9,10,12-hexahydro-naphthacene, and non-toxic acid addition salts thereof.
- 8. The naphthacene derivative according to claim 2 which is 4-methoxy-5,12-dioxo-6,9,11-trihydroxy-7-(2,3,6-O-tridesoxy-3-amino-1-L-lyxohexosyl)-9-[1-(4-methylthiosemicarbazono)ethyl]-5,7,8,9,10,12-hexahydro-naphthacene and non-toxic acid addition salts thereof.
- 9. The naphthacene derivative according to claim 1 which is 4-methoxy-5,12-dioxo-6,9,11-trihydroxy-7-(2,3,6-O-tridesoxy-3-amino-1-L-lyxohexosyl)-9-[1-(benzoylhydrazono)ethyl]-5,7,8,9,10,12-hexahydronaphthacene and non-toxic acid addition salts thereof.
- 10. A naphthacene according to claim 1 in which R.sub.1 and R.sub.2 are both oxygen and R.sub.3 is alkanoyl of up to 4 carbon atoms or benzoyl, and non-toxic salts thereof.
Priority Claims (9)
Number |
Date |
Country |
Kind |
124943/67 |
Oct 1967 |
UK |
|
2648/68 |
Sep 1968 |
SF |
|
14582/68 |
Oct 1968 |
SF |
|
203181/68 |
Oct 1968 |
SF |
|
38326/68 |
Oct 1968 |
SF |
|
106490/68 |
Oct 1968 |
SF |
|
43-75538 |
Oct 1968 |
JA |
|
43-494 |
Oct 1968 |
JA |
|
67.124943 |
Oct 1967 |
FR |
|
Parent Case Info
This application is a Continuation-in-Part of our Application Ser. No. 768532 filed Oct. 17th 1968, and now abandoned.
US Referenced Citations (2)
Number |
Name |
Date |
Kind |
3590028 |
Arcamone et al. |
Jun 1971 |
|
3686163 |
Arcamone et al. |
Aug 1972 |
|
Continuation in Parts (1)
|
Number |
Date |
Country |
Parent |
768532 |
Oct 1968 |
|