Armstrong et al., "Distribution of Cholinergic Neurons in Rat Brain: Demonstrated by the Immunocytochemical Localizaton of Choline Acetyltransferase" J. Comp. Neurol. 216:53-68 (1983). |
Baldwin et al., "Structure, evolution and regulation of a fast skeletal muscle troponin I gene" Proc. Natl. Acad. Sci., USA 82:8080-8084 (1985). |
Barnard et al., "Translation of exogenous messenger RNA coding for nicotinic acetylcholine receptors produces functional receptors in Xenopus oocytes" Proc. R. Soc. Lond. B. 215:241-246 (1982). |
Boulter et al., "Isolation of a Clone Coding for the .alpha.-Subunit of a Mouse Acetylcholine Receptor" J. Neurosci. 5(9):2545-2552 (1985). |
Boulter et al., "Isolation of a cDNA clone coding for a possible neural nicotinic acetylcholine receptor .alpha.-subunit" Nature 319:368-374 (1986). |
Boulter et al., "Functional expression of two neuronal nicotinic acetylcholine receptors from cDNA clones identifies a gene family" Proc. Natl. Acad. Sci., USA 84:7763-7767 (1987). |
Breitbart and Nadal-Ginard, "Developmentally Induced, Muscle-Specific Trans Factors Control the Differential Splicing of Alternative and Constitutive Troponin T Exons" Cell 49:793-803 (1987). |
Brockes and Hall "Synthesis of Acetylcholine Receptor by Denervated Rat Diaphragm Muscle" Proc. Natl. Acad. Sci., USA 72(4):1368-1372 (1975). |
Brown and Fumagalli, "Dissociation of .alpha.-bungarotoxin binding and receptor block in the rat superior cervical ganglion" Brain Res. 129:165-168 (1977). |
Brown et al., "The action of cholinomimetic substances on impulse conduction in the habenulointerpeduncular pathway of the rat in vitro" J. Physiol. 353:101-109 (1984). |
Buonanno and Merlie, "Transcriptional Regulation of Nicotinic Acetylcholine Receptor Genes during Muscle Develoment" J. Biol. Chem. 261(25):11452-11455 (1986). |
Carbonetto et al., "Nonequivalence of .alpha.-bungarotoxin receptors and acetylcholine receptors in chick sympathetic neurons" Proc. Natl Acad. Sci., USA 75(2):1016-1020 (1978). |
Chiappinelli and Dryer, "Nicotinic transmission in sympathetic ganglia: blockade by the snake venom neurotoxin kappa-bungarotoxin" Neurosci. Lett. 50:239-244 (1984). |
Clarke et al., "Nicotinic Binding in the Rat Brain: Autoradiographic Comparison of [.sup.3 H]Acetylcholine, [.sup.3 H]Nicotine, and [.sup.125 H]-.alpha.-Bungarotoxin" J. Neurosci. 5(5):1307-1315 (1985). |
Claudio et al., "Nucleotide and deduced amino acid sequences of Torpedo californica acetylcholine receptor .gamma. subunit" Proc. Natl. Acad. Sci., USA 80:1111-1115 (1983). |
Conti-Tronconi et al., "Brain and muscle nicotinic acetylcholine receptors are different but homologous proteins" Proc. Natl. Acad. Sci., USA 82:5208-5212 (1985). |
Cox et al., "Detection of mRNAs in Sea Urchin Embryos by in Situ Hybridizaton Using Aasymmetric RNA Probes" Dev. Biol. 101:485-502 (1984). |
Deneris et al., "Primary Structure and Expression of .beta.2: A novel Subunit of Neuronal Nicotinic Acetylcholine Receptors" Neuron 1:45-54 (1988). |
Devillers-Thiery et al., "Complete mRNA coding sequence of the acetylcholine binding .alpha.-subunit of Torpedo marmorata acetylcholine receptor: A model for the transmembrane organization of the polypeptide chain" Proc. Natl Acad. Sci., USA 80:2067-2071 (1983). |
Evans et al., "Muscle Acetylcholine Receptor Biosynthesis: Regulation by Transcript Availability" J. Biol. Chem. 262(10):4911-4916 (1987). |
Finer-Moore and Stroud, "Amphipathic analysis and possible formation of the ion channel in an acetylcholine receptor" Proc. Natl. Acad. Sci., USA 81:155-159 (1984). |
Fischbach and Schuetze, "A post-natal decrease in acetylcholine channel open time at rat end-plates" J. Physiol. 303:125-137 (1980). |
Giraudat et al., "Structure of the High-Affinity Binding Site for Noncompetitive Blockers of the Acetylcholine Receptor: [.sup.3 H]-Chlorpromazine Labels Homologous Residues in the .beta. and .delta. Chains" Biochem. 26:2410-2418 (1987). |
Goldman et al., "Muscle Denervation Increases the Levels of Two mRNAs Coding for the Acetylcholine Receptor .alpha.-Subunit" J. Neurosci. 5:2553-2558 (1985). |
Goldman et al., "Mapping of brain areas expressing RNA homologous to two different acetylcholine receptor .alpha.-subunit cDNAs" Proc. Natl. Acad. Sci., USA 83:4076-4080 (1986). |
Goldman et al., "Members of a Nicotinic Acetylcholine Receptor Gene Family Are Expressed in Different Regions of the Mammalian Central Nervous System" Cell 48:965-973 (1987). |
Gorman et al., "Recombinant Genomes Which Express Chloramphenicol Acetyltransferase in Mammalian Cells" Mol. Cell. Biol. 2(9):1044-1051 (1982). |
Greene and Tischler, "Establishment of noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor" Proc. Natl. Acad. Sci., USA 73:(7)2424-2428 (1976). |
Grenningloh et al., "The strychnine-binding subunit of the glycine receptor shows homology with nicotinic acetylcholine receptors" Nature 328:215-220 (1987). |
Guy, H. R., "A structural model of the acetylcholine receptor channel based on partition energy and helix packing calculations" Biophys. J. 45:249-261 (1984). |
Guy and Hucho, "The ion channel of the nicotinic acetylcholine receptor" Trends Neurosci 10(8):318-321 (1987). |
Hanke and Breer, "Channel properties of an insect neuronal acetylcholine receptor protein reconstituted in planar lipid bilayers" Nature 321:171-174 (1986). |
Hartzell and Fambrough, "Acetylcholine Receptors: Distribution and extrajunctional density in rat diaphragm after denervation correlated with acetylcholine sensitivity" J. Gen. Physiol. 60:248-262 (1972). |
Heidmann et al., "Chromosomal Localizaton of Muscle Nicotinic Acetylcholine Receptor Genes in the Mouse" Science 234:866-868 (1986). |
Heinemann et al., "Molecular Biology of the Muscle Land Neural Acetylcholine Receptors" In: Nicotinic Acetylcholine Receptor: Structure and Function, NATO ASI Series H, A. Maelicke, ed. (Berlin: Springer-Verlag), H3:359-387 (1986). |
Higgins and Berg, "Immunological Identification of a Nicotinic Acetylcholine Receptor on Bovine Chromaffin Cells" J. Neurosci. 7(6):1792-1798 (1987). |
Houser et al., "Organization and Morphological Characteristics of Cholinergic Neurons: an Immunocytochemical Study with a Monoclonal Antibody to Choline Acetyltransferase" Brain Res. 266:97-119 (1983). |
Hucho et al., "The ion channel of the nicotinic acetylcholine receptor in formed by the homologous helices M II of the receptor subunits" FEBS Lett. 205(1)137-142 (1986). |
Huganir et al., "Phosphorylation of the nicotinic acetylcholine receptor regulates its rate of desensitization" Nature 321:774-776 (1986). |
Ichikawa and Hirata, "Organization of Choline Acetyltransferase-Containing Structures in the Forebrain of the Rat" J. Neurosci. 6(1):281-292 (1986). |
Imoto et al., "Location of a .delta.-subunit region determining ion transport through the acetylcholine receptor channel" Nature 324:670-674 (1986). |
Jaynes et al., "Transcriptional Regulation of the Muscle Creatine Kinase Gene and Regulated Expression in Transfected Mouse Myoblasts" Mol. Cell. Biol. 6(8):2855-2864 (1986). |
Kao and Karlin, "Acetylcholine Receptor Binding Site Contains a Disulfide Cross-link between Adjacent Half-Cystinyl Residues" J. Biol. Chem. 261(18):8085-8088 (1986). |
Karlin, A., "Chemical Modification of the Active Site of Acetylcholine Receptor" J. Gen. Phys. 54:245s-264s (1969). |
Kemp et al., "Purification and Characterization of the .alpha.-Bungarotoxin Binding Protein from Rat Brain" Brain Res. 347:274-283 (1985). |
Klarsfeld et al., "A 5-Flanking Region of the Chicken Acetylcholine Receptor .alpha.-Subunit Gene Confers Tissue Specificity and Develomental Control of Expression in Transfected Cells" Mol. Cell. Biol. 7(2):951-955 (1987). |
Kurosaki et al., "Functional properties of nicotinic acetylcholine receptor subunits expressed in various combinations" FEBS Lett. 214(2):253-258 (1987). |
Lamour et al., "Spread of acetylcholine sensitivity in the necocortex following lesion of the nucleus basalis" Brain Res. 252:377-381 (1982). |
Lichtensteiger et al., "Stimulation of Nigrostriatal Dopamine Neurones by Nicotine" Neuropharmacol. 21:963-968 (1982). |
Martin, B. R., "Nicotine Receptors n the Central Nervous System" In: The Receptors, P. M. Conn, ed. (Orlando, FL: Academic Press) 3:393-415 (1986). |
Mauron et al., "Structure of Chicken Genes Encoding the Nicotinic Acetylcholine Receptor Subunits and Their Variants" Soc. for Neuroscience, 15th Annual Meeting, Abstract 55.10, p. 171 (1985). |
McCarthy et al., "The molecular Neurobiology of the Acetylcholine Receptor" Ann. Rev. Neurosci. 9:383-413 (1986). |
McCormick and Prince, "Acetylcholine Causes Rapid Nicotinic Excitation in the Medial Habenular Nucleus of Guinea Pig, in vitro" J. Neurosci. 7(3):742-752 (1987). |
Michler and Sakmann, "Receptor Stability and Channel Conversion in the Subsynaptic Membrane of the Developing Mammalian Neuromuscular Junction" Dev. Biol. 80:1-17 (1980). |
Mishina et al., "Expression of functional acetylcholine receptor from cloned cDNAs" Nature 307:604-608 (1984). |
Mishina et al., "Molecular distinction between fetal and adult forms of muscle acetylcholine receptor" Nature 321:406-411 (1986). |
Mulac-Jercevic and Atassi, "Segment .alpha.182-198 of Torpedo californica acetylcholine receptor contains a second toxin-binding region and binds anti-receptor antibodies" FEBS Lett. 199(1):68-74 (1986). |
Nef et al., "Structure linkage, and sequence of the two genes encoding the .delta. and .gamma. subunits of the nicotinic acetylcholine receptor" Proc. Natl. Acad. Sci., USA 81:7975-7979 (1984). |
Nef et al., "Acetylcholine Receptor Related Genes Expressed in the Nervous System" In: Nicotinic Acetylcholine Receptor: Structure and Function, NATO ASI Series, vol. H3, A. Maelicke, ed., (Springer-Verlag) pp. 417-422 (1986). |
Nef et al., "Genes expressed in the brain define three distinct neuronal nicotinic acetylcholine receptors" EMBO J. 7(3):595-601 (1988). |
Neumann et al., "Mapping of the .alpha.-bungarotoxin binding site within the .alpha. subunit of the acetylcholine receptor" Proc. Natl. Acad. Sci., USA 83:3008-3011 (1986). |
Noda et al., "Primary structure of .alpha.-subunit precursor of Torpedo californica acetylcholine receptor deduced from cDNA sequence" Nature 299:793-797 (1982). |
Noda et al,. "Structural homology of Torpedo californica acetylcholine receptor subunits" Nature 302:528-532 (1983). |
Noda et al., "Cloning and sequence analysis of calf cDNA and human genomic DNA encoding .alpha.-subunit precursor of muscle acetylcholine receptor" Nature 305:818-823 (1983). |
Oswald and Freeman, "Alpha-Bungarotoxin Binding and Central Nervous System Nicotinic Acetylcholine Receptors" Neuroscience 6:1-14 (1981). |
Patrick and Stallcup, "Immunological distinction between acetylcholine receptor and the .alpha.-bungarotoxin-binding component on sympathetic neurons" Proc. Natl. Acad. Sci., USA 74(10):4689-4692 (1977). |
Patrick and Stallcup, ".alpha.-Bungarotoxin Binding and Cholinergic Receptor Function on a Rat Sympathetic Nerve Line" J. Biol. Chem. 252:8629-8633 (1977). |
Patrick et al., "Molecular Cloning of the Acetylcholine Receptor" Cold Spring Harbor Symposia on Quantitative Biology XLVIII:71-79 (1983). |
Pearson et al., "The cortical relationships of certain basal ganglia and the cholinergic basal forebrain nuclei" Brain Res. 261:327-330 (1983). |
Popot and Changeux, "Nicotinic Receptor of Acetylcholine: Structure of an Oligomeric Integral Membrane Protein" Physiological Revs. 64(4):1162-1239 (1984). |
Rang, H. P., "The Characteristics of Synaptic Currents and Responses to Acetylcholine of Rat Submandibular Ganglion Cells" J. Physiol. 311:23-55 (1981). |
Ravdin and Berg, "Inhibition of neuronal acetylcholine sensitivity by .alpha.-toxins from Bungarus multicinctus venom" Proc. Natl. Acad. Sci., USA 76(4):2072-2076 (1979). |
Rotter and Jacobowitz, "Neurochemical Identification of Cholinergic Forebrain Projection Sites of the Nucleus Tegmentalis Dorsalis Lateralis" Brain Res. Bull. 6:525-529 (1981). |
Safran et al,. "Analysis of acetylcholine receptor phosphorylation sites using antibodies to synthetic peptides and monoclonal antibodies" EMBO J. 5:3175-3178 (1986). |
Schoepfer et al., "cDNA Clone Coding for the Structural Subunit of a Chicken Brain Nicotinic Acetylcholine Receptor" Neuron 1:241-248 (1988). |
Schofield et al., "Sequence and functional expression of the GABA.sub.A receptor shows a ligand-gated receptor super-family" Nature 328:221-227 (1987). |
Schubert et al., "Characterization of a Unique Muscle Cell Line" J. Cell. Bio. 61:398-413 (1974). |
Sebbane et al., "Characterization of the mRNA for Mouse Muscle Acetylcholine Receptor .alpha. Subunit by Quantitative Translation in Vitro" J. Biol. Chem. 258:3294-3303 (1983). |
Shibahara et al,. "Cloning and sequencing analysis of human genomic DNA encoding .gamma. subunit precursor of muscle acetylcholine receptor" Eur. J. Biochem. 146:349-359 (1985). |
Smith et al., "Characterization of a Component in Chick Ciliary Ganglia that Cross-reacts with Monoclonal Antibodies to Muscle and Electric Organ Acetylcholine Receptor" J. Neurosci. 5(10):2726-2731 (1985). |
Stroud and Finer-Moore, "Acetylcholine Receptor Structure, Function, and Evolution" Ann. Rev. Cell. Biol. 1:317-351 (1985). |
Sugiyama and Yamashita, "Characterization of Putative Nicotinic Acetylcholine Receptors Solubilized from Rat Brains" Brain Res. 373:22-26 (1986). |
Swanson et al., "Immunohistochemical localization of monoclonal antibodies to the nicotinic acetylcholine receptor in chick midbrain" Proc. Natl. Acad. Sci., USA 80:4532-4536 (1983). |
Swanson et al., "Immunohistochemical Localization of Neuronal Nicotinic Receptors in the Rodent Central Nervous System" J. Neurosci. 7(10):3334-3342 (1987). |
Takai et al., "Cloning, sequencing and expression of cDNA for a novel subunit of acetylcholine receptor from calf muscle" Nature 315:761-764 (1985). |
Vicini and Schuetze, "Gating Properties of Acetylcholine Receptors at Developing Rat Endplates" J. Neurosci. 5(8):2212-2224 (1985). |
Wada et al,. "Functional Expression of a New Pharmacological Subtype of Brain Nicotinic Acetylcholine Receptor" Science 240:330-334 (1988). |
Weill et al., "Affinity-Labeling of Purified Acetylcholine Receptor from Torpedo Californica" Biochem. Biophys. Res. Commun. 61(3):997-1003 (1974). |
Whiting and Lindstrom, "Pharmacological Properties of Immuno-Isolated Neuronal Nicotinic Receptors" J. Neurosci. 6(10):3061-3069 (1986). |
Whiting and Lindstrom, "Purification and Characterization of a Nicotinic Acetylcholine Receptor from Chick Brain" Biochem. 25:2082-2093 (1986). |
Whiting and Lindstrom, "Affinity labelling of neuronal acetylcholine receptors localizes acetylcholine-binding sites to their .beta.-subunits" FEBS Lett. 213(1):55-60 (1987). |
Whiting et al., "Functional acetylcholine receptor in PC12 cells reacts with a monoclonal antibody to brain nicotinic receptors" Nature 327:515-518 (1987). |
Whiting et al., "Neuronal nicotinic acetylcholine receptor .beta.-subunit is coded for by the cDNA clone .alpha..sub.4 " FEBS Lett. 219(2):459-463 (1987). |
Whiting and Lindstrom, "Purification and characterization of a nicotinic acetylcholine receptor from rat brain" Proc. Natl. Acad. Sci., USA 84:595-599 (1987). |
Wilson et al., "Determination of the primary amino acid sequence specifying the .alpha.-bungarotoxin binding site on the .alpha. subunit of the acetylcholine receptor for Torpedo californica" Proc. Natl. Acad. Sci., USA 82:8790-8794 (1985). |
Wonnacott, S., ".alpha.-Bungarotoxin Binds to Low-Affinity Nicotine Binding Sites in Rat Brain" J. Neurochem. 47:1706-1712 (1986). |
Patrick et al, P.N.A.S. 74:4689-4692, Oct. 1977. |
Mothfessel et al., Pflugers Arch. 407(6):577-588, Dec. 1986, Abstract. |
Whiting et al., P.N.A.S. 84:595-599, Jan. 1987. |