NEW DEVICE FOR MICRODOSIMETRY

Information

  • Research Project
  • 3491814
  • ApplicationId
    3491814
  • Core Project Number
    R43CA045869
  • Full Project Number
    1R43CA045869-01
  • Serial Number
    45869
  • FOA Number
  • Sub Project Id
  • Project Start Date
    9/17/1987 - 37 years ago
  • Project End Date
    7/15/1988 - 36 years ago
  • Program Officer Name
  • Budget Start Date
    9/17/1987 - 37 years ago
  • Budget End Date
    7/15/1988 - 36 years ago
  • Fiscal Year
    1987
  • Support Year
    1
  • Suffix
  • Award Notice Date
    9/17/1987 - 37 years ago

NEW DEVICE FOR MICRODOSIMETRY

This proposal deals with the development of a radiation detector that will make possible the direct measurement of the structure of charged particle tracks in a gas. Such a detector will permit the measurement of microdosimetric distributions in volumes that correspond to nanometers in a biological cell, e.g., the diameter of a DNA molecule. When a charged particle penetrates a gas, electrons produced during ionization events quickly become thermalized. The proposed detector would determine the positions of all of these electrons by imposing a suitable rf field, causing the electrons to agitate and excite molecules of the gas which would then fluoresce producing photons that could be detected by an external optical detector. In Phase I an experimental proof of concept would be made that a single charged particle track could be detected optically. In Phase II, vidicon or other CCD detectors would be used to obtain spatially resolved images of all of the electrons produced in the track of a single charged particle. In Phase III the new detector would be developed and marketed.

IC Name
NATIONAL CANCER INSTITUTE
  • Activity
    R43
  • Administering IC
    CA
  • Application Type
    1
  • Direct Cost Amount
  • Indirect Cost Amount
  • Total Cost
  • Sub Project Total Cost
  • ARRA Funded
  • CFDA Code
    395
  • Ed Inst. Type
  • Funding ICs
  • Funding Mechanism
  • Study Section
    SSS
  • Study Section Name
  • Organization Name
    PELLISSIPPI INTERNATIONAL
  • Organization Department
  • Organization DUNS
  • Organization City
    KNOXVILLE
  • Organization State
    TN
  • Organization Country
    UNITED STATES
  • Organization Zip Code
    37932
  • Organization District
    UNITED STATES