Generally, the field of art of the present disclosure pertains to particle accelerator systems and methods, and more particularly, to non-scaling fixed field alternating gradient (FFAG) permanent magnet accelerator systems and methods and associated applications such as cancer therapy and the like.
Generally, particle accelerators use electromagnetic fields to propel charged particles at high speeds in well-defined beams. Exemplary applications of particle accelerators include physics experiments, medical applications, energy production, and the like. Exemplary particle accelerators include cyclotrons, synchrotrons, and fixed field alternating gradient accelerators. An exemplary medical application includes proton therapy using a beam of protons to irradiate diseased tissue, such as in the treatment of cancer. Conventionally, most proton and carbon cancer therapy facilities use cyclotrons, with a few exceptions where synchrotrons are used. This is mostly due to cyclotrons' competitive price and ease of operation. Cyclotrons have several disadvantages for proton therapy and the like. First, protons are accelerated in cyclotrons in a continuous mode at maximum energy. To obtain a required energy for a patient, a treatment degrader material is used, and protons lose energy passing through this material. Disadvantageously, this induces radioactivity and has negative impact on beam emittance. Also, cyclotrons always have continuous losses especially at an extraction point. This makes cyclotrons difficult to operate and/or repair, as they need to “cool down” with respect to residual radioactivity (e.g., the cool down period can be up to 10 days). The residual radioactivity also requires building special shielding walls to allow safe operation thereby making installation difficult in medical treatment facilities, for example. Synchrotrons solve the aforementioned problems, but are larger in size, and do not operate continuously. If synchrotrons are fast cycling (i.e., maximum possible today ˜60 Hz), they can be competitive to cyclotrons.
Fixed field alternating gradient (FFAG) accelerators are circular particle accelerators that combine the cyclotron advantage of continuous, unpulsed operation, with the synchrotron advantage of relatively inexpensive small magnet ring, of narrow bore. There are two types of FFAG accelerators: scaling and non-scaling (NS). Relative to conventional particular accelerators, there is a need in the art for non-scaling FFAG accelerator systems and methods to address fast acceleration to reduce treatment time, cost considerations both in operation and capital, operational simplicity, and reduction in size.
In an exemplary embodiment, a non-scaling fixed field alternating gradient accelerator includes a racetrack shape including a first straight section connected to a first arc section, the first arc section connected to a second straight section, the second straight section connected to a second arc section, and the second arc section connected to the first straight section; and matching cells configured to match particle orbits between the first straight section, the first arc section, the second straight section, and the second arc section. The first arc section and the second arc section each can include permanent magnets, and the permanent magnets can be a Halbach type. The accelerator can further include an injection septum, a cavity, and an injection kicker in the first straight section configured to receive high energy particles; and at least one extraction kicker and an extraction septum in the second straight section configured to eject the high energy particles. The matching cells can include a first matching cell between the first arc section, the first straight section, and the second arc section; and a second matching cell between the first arc section, the second straight section, and the second arc section; wherein each of the first matching cell and the second matching cell can include six magnets including four quadrupoles and two dipoles.
100071 Each of the first matching cell and the second matching cell can include adjustable variables for matching conditions associated with a single particle energy value. The four quadrupoles can include two defocusing quadrupoles and two focusing quadrupoles and the two dipoles each include opposing bending magnets. The first straight section and the second straight section each can include two halves which are symmetric to one another. Due to symmetry in the first straight section and the second straight section, the matching cells only require a solution for matching particle orbits from one end of one of the first arc section and the second arc section to a middle of one of the first straight section and the second straight section. The matching cells can be configured to take values of the orbits and betatron amplitude functions and propagate them through the first straight section for each momentum coming to same conditions at the first arc section and through the second straight section for each momentum coming to same conditions at the second arc section.
In another exemplary embodiment, a non-scaling fixed field alternating gradient accelerator includes a first matching cell connecting a first arc section to a second arc section with an intermediate first straight section, wherein the first matching cell is configured to match particle orbits between the first straight section and the first arc section and between the first straight section and the second arc section; and a second matching cell connecting the first arc section to the second arc section with an intermediate second straight section, wherein the second matching cell is configured to match particle orbits between the second straight section and the first arc section and between the second straight section and the second arc section. The first arc section and the second arc section each can include permanent magnets, and the permanent magnets can be a Halbach type. The accelerator can further include an injection septum, a cavity, and an injection kicker in the first straight section configured to receive high energy particles; and at least one extraction kicker and an extraction septum in the second straight sections configured to eject the high energy particles. Each of the first matching cell and the second matching cell can include six magnets including four quadrupoles and two dipoles.
Each of the first matching cell and the second matching cell can include adjustable variables for matching conditions associated with a single particle energy value. The four quadrupoles can include two defocusing quadrupoles and two focusing quadrupoles and the two dipoles each include opposing bending magnets. The first straight section and the second straight section each can include two halves which are symmetric to one another; and, due to symmetry in the first straight section and the second straight section, the matching cells only require a solution for matching particle orbits from one end of one of the first arc section and the second arc section to a middle of one of the first straight section and the second straight section. The first matching cell can be configured to take values of the orbits and betatron amplitude functions and propagate them through the first straight section for each momentum coming to same conditions at the first arc section; and the second matching cell can be configured to take values of the orbits and betatron amplitude functions and propagate them through the second straight section for each momentum coming to same conditions at the second arc section.
In yet another exemplary embodiment, a method of designing a non-scaling fixed field alternating gradient accelerator as a racetrack includes determining stable particle orbits for a ring structure including repeating cells; breaking the ring structure into two separate arc structures; providing two straight sections between the two separate arc structures; and providing magnets in each of the two straight sections, wherein the magnets are configured to take values of the orbits and betatron amplitude functions and propagate them through a straight section for each momentum coming to same conditions at an arc structure.
Exemplary and non-limiting embodiments of the present disclosure are illustrated and described herein with reference to various drawings, in which like reference numbers denote like method steps and/or system components, respectively, and in which:
In various exemplary embodiments, the present disclosure relates to NS-FFAG accelerator systems and methods utilizing a “racetrack” design with permanent magnets. The accelerator includes two straight sections connected by two arcs on opposite sides. In an exemplary embodiment, the accelerator systems and methods offer a competitive design for a cancer therapy accelerator relative to conventional cyclotrons or slow extraction synchrotrons used today for cancer therapy accelerators. The accelerator systems and methods can include a racetrack NS-FFAG with fast acceleration assumed with a total number of turns less than 1000. Additionally, the accelerator systems and methods can use permanent separated function magnets of the Halbach structure. In an exemplary embodiment, the orbit offsets presented are within a range 11 mm<Δx<17 mm. This allows use of an aperture of about 30 mm. With an outside diameter of 7.375 cm from the available Nd—Fe—B (for temperatures less than 70 deg. C.) materials a bending dipole field of 2.4 T could be obtained. Advantageously, the accelerator systems and methods include very small magnets and simplified operation, as the magnets are permanent. Acceleration is assumed to be with a fast phase jump scheme where the voltage on the cavities is changed within one turn of the circulating bunch.
The straight sections serves to inject and extract protons. The straight sections accelerates protons via the radiofrequency cavities. As the energy of the protons change throughout the NS-FFAG accelerator, orbits of the proton beam in the arcs oscillate at different radii. Although the differences in the radii are very small in range (−11 mm to −17 mm) they need to be merged going through the straight sections into one orbit. Until the present invention, the beam had not been merged with a NS-FFAG accelerator. It took the inventor over 75 trials to achieve this alignment.
Referring to
In an exemplary application, the accelerator 10 can be used as a proton therapy accelerator from 31 MeV to 250 MeV. The dipole bending field is 2.3 T, while the Neodymium Iron Boron magnetic residual induction is Br=1.3 T. The radial orbit offsets in the arc sections 16, 18, for the kinetic energy range between 31 MeV<Ek<250 MeV or momentum offset range −50%<δp/p<50%, are −11.6 mm<xmax<16.8 mm, correspondingly. The straight sections 12, 14 are used for the cavities 23 and single turn injection/extraction kickers 21, 24, 25 and septa 22, 26 are with zero orbit offsets. Advantageously, use of permanent magnets reduces overall capital and operating cost. The accelerator 10 can be used, for example, in proton/carbon ion cancer therapy facilities although other applications are also contemplated. From a design perspective, the accelerator 10 seeks to address two disadvantages of conventional systems and methods, namely cost and size. With respect to cyclotrons, the accelerator 10 includes advantages of providing variable energy without degraders (which introduce radiation and beam emittance blow-up), and the single turn extraction avoids beam loss and residual radiation. With respect to synchrotrons, the accelerator 10 includes advantages of fast acceleration rate making therapy treatments shorter allowing fast spot scanning techniques.
Referring to
where Br is the material permanent magnetic field value, while OD and ID are outside and inside diameters of the material modules.
Referring to
In an exemplary embodiment, the length of the elements 42, LQF/2, is 6.05 cm, the length of the magnets 44, LB, is 3.8 cm, the length of the element 46, LQD, is 9.2 cm, and the end-to-end length of the cell 40 is 29.7 cm. There is an optimal choice for the magnet 42, 44, 46 lengths with respect to the smallest orbit offsets which also define the size of the accelerator 10. At the same time the length of the dipole magnets 44 is chosen to allow the required angle=2*PI/Ndipoles. A total number of dipoles is 120, two per each cell for the total of 60 cells for the whole circle or 30 cells per each arc in the racetrack configuration. The cell 40 includes a center reference line 50 through the elements 42, 44, 46. From this reference line 50, proton kinetic energy 52 is shown in a range of 30-250 MeV. Specifically, at a distance approximately 16.8 mm from the reference line 50, the proton kinetic energy 52 is approximately 250 MeV and at a distance of approximately −10.5 mm from the reference line 50 in an opposite direction, the proton kinetic energy 52 is approximately 30 MeV.
Referring to
Referring to
The matching cell 20 has to accommodate numerous constraints. First, at a specific energy, four amplitude functions and their slopes [βx, βy, αx, αy] from the arc sections 16, 18 have to match the ones from the straight sections 12, 14 as well and the dispersion function with its slope Dx and Dx′. Next, radial orbit offsets in the arc sections 16, 18 at the specific energy need to be annulled so the particles continue with zero slopes at the end of the matching cell 20. Third, in addition to these constraints above, the same conditions are required for any energy during acceleration from the minimum to the maximum energies (e.g., 30 MeV-250 MeV). For the matching cell 20, available variables include four gradients in the quadrupoles, two bending angles of the dipoles, and distances between the magnets 70, 72, 74, 76, 78, 80. A major difficulty in this matching procedure in the matching cell 20 is that it is possible to match conditions at only single particle energy.
The design of the accelerator 10 requires finding solutions for the largest and smallest energy. This was performed by a trial and error procedure, i.e., solutions for the highest energy (250 MeV) were applied for the smallest energy (30 MeV) and opposite until both conditions were fulfilled. Over 75 trials were required. In this process, an additional constraint for the orbit offsets and their slopes was used in a multiple fitting procedure. After the solution was obtained by the SYNCH code, an additional Polymorphic Tracking Code (author is Etienne Forest, KEK Japan) was used to confirm the obtained solutions and do the final check.
The design of the accelerator 10 includes a matching procedure 100 to match particle orbits between the sections 12, 14, 16, 18. The matching procedure 100 uses an accelerator physics program called SYNCH (authored by A. Garren and Ernest Courant) (available online at www.cap.bnl.gov/SYNCH). In particular, the SYNCH program can be used to solve the problem of matching orbits and Courant-Snyder invariants for different energies—momenta—(amplitude functions βx, βy and their slopes αx and αy for the horizontal and vertical transverse motion of the particles in the accelerator).
The matching procedure 100, using the SYNCH program, produces required values for the Courant-Snyder amplitude functions starting with defined initial conditions using enough variables. In the context of the accelerator 10, two structures are required one for the straight sections 12, 14 and one for the arc sections 16, 18. The periodic structure of the arcs cells has created stable orbits for protons between kinetic energies of 31-250 MeV. That is, protons with kinetic energies of 31-250 MeV have stable orbits in the arc sections 16, 18 as shown by the particle orbits 64 in
Initial conditions for the matching procedure 100 are very well defined from the closed orbits of the non-scaling Fixed Field Alternating Gradient ring 60 presented in
Due to the symmetry conditions it is enough to create a solution from the end of one arc section 16, 18 to the middle of the straight section 12, 14 by requiring that the slopes of the betatron functions alpha-x, alpha-y=0, matching of the orbit offset VDX, and matching of the slope of the dispersion function DX. The major advantage of the SYNCH program is that it allows calculations and initial conditions of the orbits. A first command for the initial conditions in SYNCH includes reading of a matrix with initial values of the betatron Functions values in SYNCH called “IBET.” These include PHASE or “TUNE-X”, “BETA-X”, slope of beta-x—“ALPHA-X”, “gammaX”, dispersion “DX”, and slope of dispersion “DXP”; PHASE or “TUNE-Y”, “BETA-Y”, slope of beta-y—“ALPHA-Y”, “gammaX”, dispersion in y “DY”, and the slope of dispersion in y-plane “DYP”. Additional initial conditions are provided by a particle vector called PVEC in SYNCH. The PVEC vector is used to define the initial phase space of one or more particles and includes positions of the particle in the transverse x-plane “x1”, slope of the particle in the x-plane “xp1”, the same for the y-plane, longitudinal positions “−ds” and the most important the “dp/p” momentum offset. In the example presented herein, the momentum offset is varying between −50%<dp/p<+50%.
Referring to
The first several rows (up to thirteen) in the command for the general fitting routine program are used to set the required values for the betatron functions: beta-x, beta-y, alpha-x, alpha-y, length of the line s, dispersion function “Dx”, slope of the dispersion function “Dpx”, and orbit offsets and slopes at the defined position. Each requirement has also added weights for the accuracy required. A simplification of the problem comes from the mirror symmetry of the straight section 12, 14. The symmetry is fulfilled if the values of the slopes are equal to zero: alpha-x=0, alpha-y=0, DPX=0, XPX=0, i.e. constraints in
Thus, the constraints for the accelerator 10 are αX=0; αY=0, βX≈1; βY≈1, DX=0, D′X=0, x′off=0, xoff=0; νX=0.25; and νY=0.25. The variables for the matching cell 20 are GFX1, GF1, GD8, GDX2, GFX3, OC1P, OC2P, OC3P, OC4P, OPIP, θBDX1, and, θBDX2. The initial conditions are defined by an initial vector and Betatron functions βx, αx, βy, αy, Dx, D′x@Δp/p=0.5, 0.4, . . . , −0.4, −0.5. The initial vector includes initial orbit offsets (xoff, x′off, yoff, y′off)@Δp/p=(0.50, 0.40, . . . , −0.50), −Δs longitudinal orbit offsets (Δs=CΔp/p−CΔp/p=0), and value of the Δp/p. To start, a total number of constraints for momentum values of: −50%, −40%, −30%, −20%, −10%, +10%, +20%, +30%, +40%,+50% leads to a total number of variables of 30 cells×2=60 different gradients +2θ+3 straight section gradients=65. However, it was determined that is in only necessary to perform the matching procedure 100 at @dp/p=+50% and @dp/p=−50%, i.e., the maximum and minimum energies to find a solution.
There are total of twenty of the general fitting routines used for the momentum offsets: dp/p=+50%, dp/p=+40%, dp/p=+30%, dp/p=0, dp/p=−10%, dp/p=20%, . . . , dp/p=−40%, and dp/p=−50%. The solutions for each value of dp/p are compared and an additional SYNCH routine called Fixed point FIXPT is used fo representing a search for the closed orbit solution for all momenta dp/p=+50, dp/p=45%, dp/p=40%, dp/p=35%, . . . dp/p=−45%, and dp/p=−50%.
Referring to
Referring to
Referring to
Referring to
Referring to
Referring to
Referring to
Referring to
The orbit offsets in the accelerator 10 are within 11 mm<Δx<17 mm allowing use of a small aperture, e.g., 35 mm. With the outside diameter of 21 cm from the available Nd—Fe'B (for temperatures less than 70 C) materials, a bending dipole field of 2.4 T could be obtained. Advantage of the accelerator is very small magnets and simplified operation, as the magnets are permanent.
Although the present disclosure has been illustrated and described herein with reference to preferred embodiments and specific examples thereof, it will be readily apparent to those of ordinary skill in the art that other embodiments and examples may perform similar functions and/or achieve like results. All such equivalent embodiments and examples are within the spirit and scope of the present disclosure and are intended to be covered by the following claims.
The parent non-provisional application claimed priority to U.S. provisional patent application Ser. No. 61/539,109, filed Sep. 26, 2011, and entitled “NON-SCALING FIXED FIELD ALTERNATING GRADIENT PERMANENT MAGNET CANCER THERAPY ACCELERATOR,” the contents of which are incorporated herein by reference. The present continuation-in-part claims priority to Ser. No. 13/461,914 which is incorporated herein by reference. Also incorporated herein by reference is the inventor's patent U.S. Pat. No. 7,582,886 B2 and Pub. No. 2010/0038552A1 for gantry delivery systems for the accelerator.
The present invention was made with government support under Contract Number DE-AC02-98CH10886 awarded to Brookhaven National Laboratory by the Department of Energy (DOE). The U.S. government has certain rights in the invention.
Number | Date | Country | |
---|---|---|---|
Parent | 13461914 | May 2012 | US |
Child | 14285706 | US |