The present disclosure relates to a computer program, an information processing device, an information processing method, and a learning model generation method.
Japanese Patent Publication No. 2010-3135 A (“Patent Literature 1”) describes a medical information management system that includes a plurality of medical department servers that provides medical information stored in a database of a plurality of medical departments in a medical institution and a specific disease treatment integrated server that acquires specific disease medical information from the medical department server and provides the integrated specific disease medical information from an integrated database, in which a treatment progressing status can be grasped with high immediacy by making it possible to refer to medical information of specific diseases such as cancer in all treatment methods combining a surgery, radiation therapy, chemotherapy, and palliative care and registered related information of the specific diseases in a wide range.
In the medical field, pain caused by diseases such as cancer is evaluated by pain measurement using an index such as a visual analog scale (VAS) or a device. These methods are cumbersome for a patient, and there is a problem that a doctor can only make evaluation only when the doctor is facing the patient. Furthermore, specialized knowledge is essential for effective pain management, and there is a problem that it is difficult for a doctor other than a specialist to perform an accurate pain treatment according to the patient.
Certain embodiments of present invention have been developed in view of the above circumstances, and an object of certain embodiments of the present invention is to provide a computer program, an information processing device, an information processing method, and a learning model generation method that can assist an appropriate pain treatment.
According to one embodiment, a non-transient computer-readable medium comprises a computer program that causes a computer to execute processing comprising: acquiring pain related information regarding pain of a patient; inputting the acquired pain related information into a learning model that outputs an index indicating an effect of a pain treatment, and acquiring from the learning model the index indicating an effect of a pain treatment regarding the patient; generating pain treatment assistance information for the patient based on the acquired index; and outputting the generated pain treatment assistance information.
According to one aspect, the pain related information includes at least one of an evaluation index used to evaluate pain, vital data, medication information, and a physical condition.
According to one aspect, the computer program causes the computer to execute processing comprising: acquiring medical information regarding medical care of the patient; and inputting the acquired medical information into the learning model that outputs the index indicating the effect of the pain treatment, and acquiring from the learning model the index indicating the effect of the pain treatment regarding the patient.
According to one aspect, the medical information includes at least one of diagnosis information, examination information, treatment information, and prescription information.
According to one aspect, the computer program causes the computer to execute processing comprising: acquiring literature information regarding a pain treatment; and inputting the acquired literature information into the learning model that outputs the index indicating the effect of the pain treatment, and acquiring from the learning model the index indicating the effect of the pain treatment regarding the patient.
According to one aspect, the pain treatment assistance information includes at least one of the index indicating the effect of the pain treatment used to assist a doctor who examines the patient, recommended prescription information, and recommended treatment information.
According to one aspect, the computer program causes the computer to execute processing comprising: outputting the pain treatment assistance information to a doctor terminal device.
According to one aspect, the computer program causes the computer to execute processing comprising: outputting a temporal change in the index indicating the effect of the pain treatment to a doctor terminal device.
According to one aspect, the computer program causes the computer to execute processing comprising: outputting introduction information of a doctor having experience in a recommended treatment method to a doctor terminal device.
According to another embodiment, a control unit programmed to execute steps comprising: acquiring pain related information regarding pain of a patient; inputting the acquired pain related information into a learning model that outputs an index indicating an effect of a pain treatment, and acquiring from the learning model the index indicating an effect of a pain treatment regarding the patient; generating pain treatment assistance information for the patient based on the acquired index; and outputting the generated pain treatment assistance information.
According to another embodiment, a method comprises: acquiring pain related information regarding pain of a patient; inputting the acquired pain related information into a learning model that outputs an index indicating an effect of a pain treatment, and acquiring from the learning model the index indicating an effect of a pain treatment regarding the patient; generating pain treatment assistance information for the patient based on the acquired index; and outputting the generated pain treatment assistance information.
According to another embodiment, a learning model generation method comprises: acquiring first training data including pain related information regarding pain of a plurality of patients and an index indicating an effect of a pain treatment regarding the plurality of patients; and generating a learning model that receives pain related information of a patient and outputs the index indicating an effect of a pain treatment regarding the patient based on the acquired first training data.
According to one aspect, the method further comprises: acquiring second training data further including medical information of the plurality of patients, literature information regarding the pain treatment, and the index indicating the effect of the pain treatment regarding the plurality of patients; and generating the learning model so as to output the index indicating the effect of the pain treatment based on the acquired second training data.
According to certain embodiments of the present invention, an appropriate pain treatment can be assisted.
Hereinafter, an embodiment of the present invention will be described.
The patient terminal device 10 is a terminal device carried or held by a patient. The patient terminal device 10 can include a smartphone, a tablet, a personal computer, or the like including a display panel, an operation panel, a microphone, a speaker, or the like. In the patient terminal device 10, an app (application) for using the pain treatment assistance system is introduced. For example, a patient who is suffering from cancer or the like and periodically visits a medical institution while being treated at home is assumed. However, the patient is not limited to such a patient. Note that an assistant such as a family member or a caregiver may operate the patient terminal device 10, on behalf of the patient. Furthermore, the app may be a Web app or a downloaded app.
The device 20 is a measuring instrument that measures vital data of the patient and may be a wearable terminal or a stationary type. The device 20 can measure the vital data such as a body temperature, a heart rate, brain waves, or electrodermal activity (EDA). Note that the vital data is not limited to these, and may include any data assumed to be related to pain caused by the patient's disease. For example, a blood pressure, a pulse pressure, pulse waves, a blood sugar level, a weight, the number of steps, an activity amount, or the like may be included in the vital data.
The doctor terminal device 30 is a terminal device used by a doctor in a medical institution or the like. The doctor terminal device 30 can include a personal computer, a tablet, or the like including a display panel, an operation panel, or the like. A medical worker such as a public health nurse or a nurse may use the doctor terminal device 30 under guidance of the doctor. An application (for example, Web app or the like) for using the pain treatment assistance system is introduced in the doctor terminal device 30.
The storage unit 59 can include, for example, a hard disk, a semiconductor memory, or the like, and stores a computer program 60 (program product), a learning model 61, and necessary information. The computer program 60 may be downloaded from an external device via the communication unit 52 and stored in the storage unit 59. Furthermore, the computer program 60 recorded in a recording medium (for example, optically readable disk storage medium such as CD-ROM) may be read by a recording medium reading unit and stored in the storage unit 59, or the computer program 60 may be read by the recording medium reading unit and developed in the memory 53.
The control unit 51 may be include a required number of central processing units (CPUs), micro-processing units (MPUs), graphics processing units (GPUs), or the like. The control unit 51 can execute processing defined by the computer program 60. That is, the processing executed by the control unit 51 corresponds to processing executed in accordance with the computer program 60. The control unit 51 can execute functions of the assistance information generation unit 58, by executing the computer program 60. The assistance information generation unit 58 may include hardware or software or may be implemented by a combination of hardware and software. The control unit 51 can execute processing using the learning model 61. Note that the control unit 51 has functions as a first acquisition unit, a second acquisition unit, a generation unit, and an output unit.
The communication unit 52 includes a communication module and can exchange necessary information with the patient terminal device 10 and the doctor terminal device 30 via the communication network 1. Furthermore, the communication unit 52 may exchange necessary information with the device 20.
The memory 53 may include a semiconductor memory, such as a static random access memory (SRAM), a dynamic random access memory (DRAM), or a flash memory. Loading the computer program 60 into the memory 53 enables the control unit 51 to execute the computer program 60.
Furthermore, the pain treatment assistance device 50 acquires medical information related to medical care of the patient from the doctor terminal device 30 via the communication unit 52. The acquired medical information is classified for each patient and for each medical care time point and stored in the medical information DB 55.
The pain evaluation index includes an intensity of pain, a change in the pain, a timing of the pain, or the like. The pain evaluation index can be transmitted from the patient terminal device 10 to the pain treatment assistance device 50, for example, when the patient activates the app of the patient terminal device 10 and answers a question regarding the intensity of the pain, the change in the pain, the timing of the pain, or the like.
The vital data includes the body temperature, the heart rate, the brain waves, the EDA, the pulse waves, or the like that changes in response to the pain. Note that the blood pressure, the pulse pressure, the blood sugar level, the weight, the number of steps, the activity amount, or the like may be included. The vital data can be acquired using the device 20.
The medication information includes a medicine type, a dosage, a medicine taking period, a medicine taking time (timing), whether or not to take the medicine, or the like. The medication information may include not only a medicine that is currently taken but also a medicine that has been taken in the past.
The physical condition includes an activity amount, a sleep time, sleepiness, lassitude, delirium, constipation, voice, facial expression, or the like. It is possible to include an item that can evaluate whether or not a disorder occurs due to the pain, the medicine, medical conditions, or the like.
The pain related information includes at least one of the pain evaluation index (evaluation index used to evaluate pain), the vital data, the medication information, and the physical condition.
By acquiring the pain related information as described above from the patient terminal device 10 and the device 20, the patient can accurately tell pain and symptoms that the patient feels at a necessary timing and a necessary frequency, in a period from a previous examination to a next examination.
The diagnosis information includes findings by interview, inspection, palpation, or percussion at the time of examination, an electronic chart, or the like. The examination information includes a blood test, a urine test, an image test, or the like. The prescription information includes a medicine type and a dosage prescribed by a doctor. Furthermore, the medicine taking period may be included. The treatment information includes a treatment method and a treatment period. Note that not only a literal treatment but also medicine prescription are included in a pain treatment.
The learning model 61 is generated (learned) to output an index indicating an effect of a current pain treatment, in a case where the pain related information is input. The index indicating the effect of the pain treatment is an index indicating a degree of the effect of the prescription or the treatment for the patient at the current time, and for example, may be expressed in several stages such as 10 stages from one to 10 or five stages from one to five. It is assumed that the pain of the patient be stronger as the index value is larger. Note that, it may be assumed that the pain of the patient be more alleviated, as the index value increases. Furthermore, the index may be classified and expressed such that the effect is appropriate, low, or high (side effects are concerned).
The learning model 61 can use, for example, a support vector machine (SVM), a decision tree, a random forest, an adaboost, a neural network (for example, recurrent neural network (RNN), long short term memory (LSTM), or the like), or the like.
The control unit 51 reads an index indicating an effect of a past pain treatment of the patient, recorded in the pain treatment assistance information DB 56. The control unit 51 inputs the read past index (index indicating effect of pain treatment) and the index acquired from the learning model 61 (index indicating effect of pain treatment) into the assistance information generation unit 58.
The assistance information generation unit 58 generates the pain treatment assistance information based on the input index (index indicating effect of pain treatment) and outputs the generated pain treatment assistance information. The assistance information generation unit 58 stores the generated pain treatment assistance information in the pain treatment assistance information DB 56. The pain treatment assistance information includes, for example, a temporal change in the index indicating the effect of the pain treatment of the patient, recommended prescription information or recommended treatment information for the patient, or the like. It is sufficient that the pain treatment assistance information include at least one of the index indicating the effect of the pain treatment used to assist the doctor who examines the patient, the recommended prescription information, and the recommended treatment information.
The temporal change in the index indicating the effect of the pain treatment includes, for example, information indicating a transition of the index of the patient from the past to the future. For example, it is sufficient that information indicate a change in the index values at a plurality of time points from a time of an initial diagnosis to the present. The recommended prescription information is information for assisting the doctor who examines the patient and includes information used to determine recommended prescription among medicine prescription for the patient. The recommended treatment information is information for assisting the doctor and includes information used to determine a recommended treatment method among treatment methods other than the medicine prescription for the patient.
The assistance information generation unit 58 may generate the pain treatment assistance information on a rule basis, for example, using a table indicating a correspondence relationship between the index indicating the effect of the pain treatment (time-series information) and the pain treatment assistance information. The table may indicate the correspondence relationship between the index indicating the effect of the pain treatment (time-series information) and the pain treatment assistance information.
Furthermore, the assistance information generation unit 58 can be configured by a model using a machine-learned algorithm and can use, for example, a support vector machine (SVM), a decision tree, a random forest, an adaboost, a neural network, or the like.
As described above, the control unit 51 can acquire the pain related information regarding the pain of the patient, input the acquired pain related information into the learning model 61 that outputs the index indicating the effect of the pain treatment, in a case where the pain related information is input and acquire the index indicating the effect of the pain treatment for the patient, generate the pain treatment assistance information for the patient based on the acquired index, and output the generated pain treatment assistance information.
Furthermore, the control unit 51 reads the literature information from the literature information DB 57 and inputs the read literature information into the learning model 61. The control unit 51 can perform the vectorization operation for generating the primary vector for the literature information, generate a literature information vector, and input the generated literature information vector into the learning model 61. It is expected that accuracy of an index output by the learning model 61 is improved by increasing the number of types of information to be input into the learning model 61.
As described above, the control unit 51 may acquire the medical information regarding the medical care of the patient, and input the acquired medical information into the learning model 61 that outputs the index indicating the effect of the pain treatment in a case where the medical information is further input and acquire the index indicating the effect of the pain treatment for the patient.
Furthermore, the control unit 51 may acquire the literature information regarding the pain treatment, and input the acquired literature information into the learning model 61 that outputs the index indicating the effect of the pain treatment in a case where the literature information regarding the pain treatment is further input and acquire the index indicating the effect of the pain treatment for the patient.
The assistance information generation unit 58 may generate the pain treatment assistance information on a rule basis, for example, using a table indicating a correspondence relationship between the index indicating the effect of the pain treatment (time-series information), the pain related information, the medical information and the literature information, and the pain treatment assistance information. The table may indicate the correspondence relationship between the index indicating the effect of the pain treatment (time-series information), the pain related information, the medical information, and the literature information, and the pain treatment assistance information.
Furthermore, as in the first and second examples, the assistance information generation unit 58 can be configured by the model using the machine-learned algorithm and can use, for example, a support vector machine (SVM), a decision tree, a random forest, an adaboost, a neural network, or the like.
Note that, in the example in
Next, a specific example of the pain treatment assistance information will be described. In the following example, in a portion where input by the doctor is needed, voice input may be used. The control unit 51 outputs the pain treatment assistance information to the doctor terminal device 30. The pain treatment assistance information is displayed on the display panel of the doctor terminal device 30, and the doctor can perform an input operation or a selection operation according to displayed content.
Furthermore, as an advice (assistance information) to the doctor, “Addition or change of medicine is needed because pain continues. How about considering changing prescription” is displayed. When the doctor operates a “recommended prescription information” icon 301, the recommended prescription information to be described later can be displayed.
As described above, the control unit 51 outputs a temporal change in the index indicating the effect of the pain treatment to the doctor terminal device 30.
Furthermore, as an advice (assistance information) to the doctor, “Pain seems to constantly occur. How about considering a new treatment method” is displayed. When the doctor operates a “recommended prescription information” icon 331, the recommended prescription information to be described later can be displayed.
As described above, the control unit 51 outputs the introduction information of the doctor having the experience in the recommended treatment method to the doctor terminal device 30.
As described above, according to the present embodiment, it is possible to support (assist) decision making on a pain treatment policy of the doctor, and even the doctor has little experience regarding the pain treatment, information necessary for the pain treatment is provided. Therefore, the doctor other than the specialist can perform an appropriate pain treatment.
The control unit 51 acquires the medical information of the patient (S13) and stores the acquired medical information in the medical information DB 55 (database) (S14). The medical information can be acquired not only at the time of examination but also when the doctor determines that the medical information is needed.
The control unit 51 inputs the pain related information of the patient, the medical information, and the literature information regarding the pain treatment into the learning model 61 and acquires the index indicating the effect of the pain treatment of the patient, output from the learning model 61 (S15). The control unit 51 reads the index indicating the effect of the past pain treatment of the patient, from the pain treatment assistance information DB 56 (database) (S16).
The control unit 51 generates the pain treatment assistance information including the temporal change in the index indicating the effect of the pain treatment of the patient, based on the index indicating the effect of the pain treatment of the patient, read from the pain treatment assistance information DB 56 and the index indicating the effect of the pain treatment of the patient, acquired from the learning model 61 (S17). In this case, the pain treatment assistance information may be generated based on the pain related information of the patient, the medical information, and the literature information, in addition to the index indicating the effect of the pain treatment of the patient.
The control unit 51 stores the generated pain treatment assistance information in the pain treatment assistance information DB 56 (database) (S18), outputs the generated pain treatment assistance information (S19), and ends the processing.
| Number | Date | Country | Kind |
|---|---|---|---|
| 2022-118145 | Jul 2022 | JP | national |
This is a bypass continuation of PCT Application No. PCT/JP2023/022149, filed on Jun. 14, 2023, which claims priority to Japanese Patent Application No. 2022-118145, filed on Jul. 25, 2022. The entire contents of these applications are incorporated herein by reference.
| Number | Date | Country | |
|---|---|---|---|
| Parent | PCT/JP2023/022149 | Jun 2023 | WO |
| Child | 19036505 | US |