Noninvasive Devices for fMRI Studies in Drug Abuse -II

Information

  • Research Project
  • 6584745
  • ApplicationId
    6584745
  • Core Project Number
    R42DA013867
  • Full Project Number
    2R42DA013867-02
  • Serial Number
    13867
  • FOA Number
  • Sub Project Id
  • Project Start Date
    6/1/2003 - 21 years ago
  • Project End Date
    1/31/2005 - 19 years ago
  • Program Officer Name
    BABCOCK, DEBRA J.
  • Budget Start Date
    6/1/2003 - 21 years ago
  • Budget End Date
    1/31/2004 - 20 years ago
  • Fiscal Year
    2003
  • Support Year
    2
  • Suffix
  • Award Notice Date
    5/27/2003 - 21 years ago

Noninvasive Devices for fMRI Studies in Drug Abuse -II

[unreadable] DESCRIPTION (provided by applicant): Insight Neuroimaging System's, LLC (INSL) mission is to develop and manufacture non-invasive tools for studying brain development, chemistry and function. INSL specializes in radiofrequency coils for ultra-high field magnetic resonance imaging for use in animal studies. MR signal is optimized by a dual coil design for RF transmission and reception. The dual coil RF electronics are built into custom, designed restrainers for non-invasive imaging with minimal stress and discomfort to the animal. INSL products have been successfully used to image fully conscious rodents and small monkeys. With STTR Phase I funding INSL developed, constructed and bench tested dual-coil animal restrainer for the large rhesus monkey. Phase I I funding will be used for field-testing, product optimization, and incorporation of an operant control panel and monitor for cognitive studies in the rhesus system. During field studies monkeys will been tested in a simulated imaging procedure to habituate them to the stress of the restrainer. Thereafter, subjects will be imaged for functional changes under control and stimulated conditions. Based upon the results of the habituation and the imaging studies, modifications will be made in the restrainer and RF electronics to optirnize the rhesus system. The INSL rhesus system can be adapted to any of the thousands of horizontal, human scanners as well as the many hundreds of dedicated horizontal animal systerns. This technology will greatly enhance preclinical research in developmental neurobiology, neurological diseases, mental illness and drug addiction. [unreadable] [unreadable]

IC Name
NATIONAL INSTITUTE ON DRUG ABUSE
  • Activity
    R42
  • Administering IC
    DA
  • Application Type
    2
  • Direct Cost Amount
  • Indirect Cost Amount
  • Total Cost
    250000
  • Sub Project Total Cost
  • ARRA Funded
  • CFDA Code
    279
  • Ed Inst. Type
  • Funding ICs
    NIDA:250000\
  • Funding Mechanism
  • Study Section
    ZRG1
  • Study Section Name
    Special Emphasis Panel
  • Organization Name
    INSIGHT NEUROIMAGING SYSTEMS, LLC
  • Organization Department
  • Organization DUNS
    153334086
  • Organization City
    WORCESTER
  • Organization State
    MA
  • Organization Country
    UNITED STATES
  • Organization Zip Code
    01610
  • Organization District
    UNITED STATES