TREA

Novel 2'- and 3'- Branched Carbocyclic Nucleosides will be synthesized and Evalua

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Information

  • Research Project
  • 8145654
  • ApplicationId
    8145654
  • Core Project Number
    R03AI088542
  • Full Project Number
    5R03AI088542-02
  • Serial Number
    88542
  • FOA Number
    PA-09-163
  • Sub Project Id
  • Project Start Date
    9/23/2010 - 14 years ago
  • Project End Date
    8/31/2012 - 12 years ago
  • Program Officer Name
    TSENG, CHRISTOPHER K.
  • Budget Start Date
    9/1/2011 - 13 years ago
  • Budget End Date
    8/31/2012 - 12 years ago
  • Fiscal Year
    2011
  • Support Year
    2
  • Suffix
  • Award Notice Date
    7/29/2011 - 13 years ago
Organizations
Information

Novel 2'- and 3'- Branched Carbocyclic Nucleosides will be synthesized and Evalua

DESCRIPTION (provided by applicant): The emergence of new viral diseases such as HCV, SARS, West Nile virus, H1N1 influenza, increased threat of bioterrorism using smallpox and appearance of new viral strains resistant to existing drugs warrants development of new medications. The goal of this proposal is to discover new antiviral candidates to treat such diseases by modifying a lead carbocyclic nucleoside analog. New analogs synthesized will be tested for antiviral activity against a wide array of viruses. PUBLIC HEALTH RELEVANCE: The goal of this proposal is to discover new antiviral candidates to treat new viral diseases such as HCV, SARS, West Nile virus, H1N1 influenza, and bioterrorism agent smallpox. The proposed research project also focuses on the development of new medications to viral strains resistant to existing drugs by modifying a lead carbocyclic nucleoside analog.

IC Name
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
  • Activity
    R03
  • Administering IC
    AI
  • Application Type
    5
  • Direct Cost Amount
  • Indirect Cost Amount
  • Total Cost
    103455
  • Sub Project Total Cost
  • ARRA Funded
    False
  • CFDA Code
    855
  • Ed Inst. Type
  • Funding ICs
    NIAID:103455\
  • Funding Mechanism
    Research Projects
  • Study Section
    ZRG1
  • Study Section Name
    Special Emphasis Panel
  • Organization Name
    ORGANIX, INC.
  • Organization Department
  • Organization DUNS
    161843057
  • Organization City
    WOBURN
  • Organization State
    MA
  • Organization Country
    UNITED STATES
  • Organization Zip Code
    018012029
  • Organization District
    UNITED STATES