Claims
- 1. A composition comprising about 103 cfu to about 1011 cfu per gram dry inert carrier of a bacterial strain that exhibits degradative activity towards a toxin.
- 2. The composition of claim 1, wherein said bacterial strain has the identifying characteristics of a bacterium designated APM-1, deposited as ATCC Accession No. PTA-4838.
- 3. The composition of claim 1, wherein said carrier comprises porous, ceramic particles.
- 4. The composition of claim 3, wherein from about 20% to about 100% of said particles have a pore size of from about 0.5 μm to about 5 μm.
- 5. The composition of claim 1, further comprising about 5% to about 40% growth medium per gram of carrier on a wt/wt dry basis.
- 6. A method of reducing the amount of a toxin in an environment, comprising applying an effective amount of the composition of claim 1 to said environment.
- 7. The method of claim 6, wherein said toxin is toxaphene.
- 8. The method of claim 6, wherein said toxin is trichloroethylene.
- 9. The method of claim 6, wherein said toxin is methylene chloride.
- 10. The method of claim 6, wherein said environment is a marine environment.
- 11. The method of claim 6, wherein said environment is soil.
- 12. The method of claim 6, wherein said environment is a toxic waste dump.
- 13. A method of identifying an inhibitor of a mammalian pathogenic fungus, comprising:
contacting a Gram-positive bacterium designated APM-1, deposited as ATCC Accession No. PTA-4838, or an extract from said bacterium with said fungus; and measuring whether growth of said pathogenic fungus is inhibited.
- 14. The method of claim 13, wherein said fungus is contacted with an aqueous extract from said bacterium.
- 15. The method of claim 13, wherein said fungus is contacted with an methanolic extract from said bacterium.
- 16. The method of claim 13, wherein said fungus is a Microsporum, Trichophyton or Epidermophyton species.
- 17. The method of claim 13, wherein said fungus is a Cladosporium or Trichosporon species.
- 18. The method of claim 13, wherein said fungus is a Candida or Aspergillus species.
- 19. The method of claim 13, wherein said fungal pathogen is a human fungal pathogen.
- 20. The method of claim 13, wherein said fungal pathogen is a fungal pathogen of dogs, cats, cattle, pigs, or sheep.
CROSS-REFERENCE TO RELATED APPLICATIONS
[0001] This application claims priority to U.S. application Ser. No. 60/343,513, filed on Dec. 21, 2001, entitled “Novel Gram Positive Antifungal Bacterium,” and U.S. application Ser. No. 10/324,240, filed on Dec. 19, 2002, entitled “Novel Antifungal Bacterium And Compositions,” both of which are incorporated herein by reference.
Provisional Applications (1)
|
Number |
Date |
Country |
|
60343513 |
Dec 2001 |
US |
Continuation in Parts (1)
|
Number |
Date |
Country |
Parent |
10324240 |
Dec 2002 |
US |
Child |
10608582 |
Jun 2003 |
US |