Claims
- 1. An antiseptic composition comprising a basic reagent and a dye.
- 2. The antiseptic composition of claim 1, wherein a basic reagent and a dye are bonded.
- 3. The antiseptic composition of claim 2, wherein a basic reagent and a dye are linked by ionic bonding.
- 4. The antiseptic composition of claim 2, wherein a basic reagent and a dye are linked by covalent bonding.
- 5. The antiseptic composition of claim 1, wherein the dye is a triarylmethane dye.
- 6. The antiseptic composition of claim 1, wherein the dye is a monoazo dye.
- 7. The antiseptic composition of claim 1, wherein the dye is a diazo dye.
- 8. The antiseptic composition of claim 1, wherein the dye is an indigoid dye.
- 9. The antiseptic composition of claim 1, wherein the dye is a xanthene dye.
- 10. The antiseptic composition of claim 1, wherein the dye is an anthraquinone dye.
- 11. The antiseptic composition of claim 1, wherein the dye is a quinoline dye.
- 12. The antiseptic composition of claim 1, wherein the dye is gentian violet or crystal viol et, ethyl violet, brilliant green, an FD&C dye, or a D&C dye.
- 13. The antiseptic composition of claim 12, wherein the FD&C dye is Blue No. 1 or Green No. 3.
- 14. The antiseptic composition of claim 5, wherein the triarylmethane dye is gentian violet.
- 15. The antiseptic composition of claim 6, wherein the monoazo dye is FD&C Yellow No. 5 or FD&C Yellow No. 6.
- 16. The antiseptic composition of claim 7, wherein the diazo dye is D&C Red No. 17.
- 17. The antiseptic composition of claim 8, wherein the indigoid dye is FD&C Blue No. 2.
- 18. The antiseptic composition of claim 9, wherein the xanthene dye is FD&C Red No. 3.
- 19. The antiseptic composition of claim 10, wherein the anthraquinone dye is D&C Green No. 6.
- 20. The antiseptic composition of claim 11, wherein the quinoline dye is D&C Yellow No. 1.
- 21. The antiseptic composition of claim 1, wherein the basic reagent is a guanidium compound, a biguanide, a bipyridine, a phenoxide antiseptic, an alkyl oxide, an aryl oxide, a thiol, a halide, an aliphatic amine, or an aromatic amine.
- 22. The antiseptic composition of claim 21, wherein the basic reagent is a guanidium compound.
- 23. The antiseptic composition of claim 22, wherein the guanidium compound is chlorhexidine.
- 24. The antiseptic composition of claim 22, wherein the guanidium compound is alexidine.
- 25. The antiseptic composition of claim 22, wherein the guanidium compound is hexamidine.
- 26. The antiseptic composition of claim 21, wherein the basic reagent is a bipyridine.
- 27. The antiseptic composition of claim 26, wherein the bipyridine is octenidine.
- 28. The antiseptic composition of claim 21, wherein the basic reagent is a phenoxide antiseptic.
- 29. The antiseptic composition of claim 28, wherein the phenoxide antiseptic is clofoctol.
- 30. The antiseptic composition of claim 28, wherein the phenoxide antiseptic is chloroxylenol.
- 31. The antiseptic composition of claim 28, wherein the phenoxide antiseptic is triclosan.
- 32. An antiseptic compound comprising a basic reagent bound to a dye.
- 33. The antiseptic compound of claim 32, wherein the basic reagent and the dye are bound ionically.
- 34. The antiseptic compound of claim 32, wherein the basic reagent and the dye are bound covalently.
- 35. The antiseptic compound of claim 32, wherein the composition is gendine, genlenol, genlosan, or genfoctol.
- 36. The antiseptic compound of claim 32, further defined by its ability to impregnate and/or coat a surface.
- 37. The antiseptic compound of claim 36, wherein the surface is composed of a polymer.
- 38. The antiseptic compound of claim 37, wherein the polymer is polyvinyl chloride, polyurethane, polyethylene, silastic elastomers, polytetrafluoroethylene, dacron, collodion, carboethane or nylon.
- 39. The antiseptic compound of claim 36, wherein said surface is composed of silicone.
- 40. The antiseptic compound of claim 36, wherein said surface is a silk suture.
- 41. The antiseptic compound of claim 36, wherein the surface is an organic surface.
- 42. The antiseptic compound of claim 41, wherein the organic surface is skin.
- 43. The antiseptic compound of claim 41, wherein the organic surface is a mucosal surface.
- 44. The antiseptic compound of claim 41, wherein the organic surface is a wound.
- 45. The antiseptic compound of claim 36, wherein the surface is an inorganic surface.
- 46. The antiseptic compound of claim 45, wherein the inorganic surface is a floor.
- 47. The antiseptic compound of claim 45, wherein the inorganic surface is a table-top.
- 48. The antiseptic compound of claim 45, wherein the inorganic surface is a counter-top.
- 49. The antiseptic compound of claim 45, wherein the inorganic surface is the surface of a hospital equipment.
- 50. The antiseptic compound of claim 45, wherein the inorganic surface is a wheelchair surface.
- 51. A medical device coated with a basic reagent and a dye.
- 52. The medical device of claim 50, wherein a basic reagent and a dye are bonded.
- 53. The medical device of claim 52 wherein the basic reagent and the dye are bound ionically.
- 54. The medical device of claim 52, wherein the basic reagent and the dye are bound covalently.
- 55. The medical device of claim 52, further selected from the group comprising an endotracheal tube, a vascular catheter, an urinary catheter, a nephrostomy tube, a biliary stent, a peritoneal catheter, an epidural catheter, a central nervous system catheter, an orthopedic device, a prosthetic valve, and a medical implant.
- 56. The medical device of claim 55, wherein said vascular catheter is a central venous catheter, an arterial line, an pulmonary artery catheter, and a peripheral venous catheter.
- 57. The medical device of claim 55, wherein said central nervous system catheter is a intraventricular shunt.
- 58. A method for coating a medical device with an antiseptic composition comprising:
a) immersing said medical device in a solvent comprising a basic reagent and a dye. b) drying the device; and c) washing off excessive composition.
- 59. The method of claim 58, wherein the solvent comprises methylene chloride, methanol, or a combination thereof.
- 60. A method for preventing nosocomial infections in a subject comprising coating a medical device that the subject is required to use with a composition comprising a basic reagent and to a dye.
- 61. The method of claim 60, wherein said subject is human.
- 62. The method of claim 60, wherein said nosocomial infection is pneumonia, bacteremia, fungimia, candidemia, a urinary tract infection, a catheter-exit site infection, and a surgical wound infection.
- 63. The method of claim 60, wherein said nosocomial infection is caused by a bacterium.
- 64. The method of claim 63, wherein said bacterium is a resistant bacterium.
- 65. The method of claim 64, wherein said resistant bacterium is selected from a group comprising methicillin-resistant staphylococci, vancomycin-resistant enterococci, and resistant Pseudomonas aeruginosa.
- 66. The method of claim 60, wherein said nosocomial infection is caused by a fungus.
- 67. The method of claim 66, wherein said fungus is a resistant fungus.
- 68. The method of claim 67, wherein said resistant fungus belongs to Candida species.
- 69. A method for disinfecting and/or sterilizing a surface comprising applying a composition comprising a basic reagent and a dye of claim 1 to the surface.
- 70. The method of claim 69, wherein the surface is an organic surface.
- 71. The method of claim 70, wherein the organic surface is selected from a group comprising, skin, a mucosal surface, and a wound surface.
- 72. The method of claim 69, wherein the surface is an inorganic surface.
- 73. The method of claim 72, wherein the inorganic surface is selected from a group comprising a floor, a table-top, a counter-top, hospital equipment, a wheel chair, gauze, cotton.
- 74. A method for disinfecting and/or sterilizing a fluid comprising adding a composition comprising a basic reagent and a dye of claim 1 into the fluid.
- 75. The method of claim 74, wherein said fluid is water.
- 76. The method of claim 74 wherein said fluid is a metal working fluid.
- 77. The method of claim 74, wherein said fluid is petroleum.
- 78. A method for preserving a substance comprising applying a composition comprising a basic reagent and a dye on the substance.
- 79. The method of claim 78, wherein the substance is selected from the group comprising wood, paint, plastic and paper.
Parent Case Info
[0001] The present invention claims priority to U.S. Provisional Application Serial No. 60/261,447 filed on Jan. 12, 2001 and U.S. Provisional Application Serial No. 60/316,165 filed on Aug. 30, 2001, which are incorporated by reference in their entirety.
Provisional Applications (2)
|
Number |
Date |
Country |
|
60261447 |
Jan 2001 |
US |
|
60316165 |
Aug 2001 |
US |