Claims
- 1. A pharmaceutical preparation for the treatment of inflammation and/or pain
- comprising a pharmaceutical effective anti-inflammatory and/or analgesic amount of a compound of the formula: ##STR1## wherein R.sub.1 is a moiety selected from the group consisting of hydrogen, halogen, CF.sub.3 and CH.sub.3,
- R.sub.2 is a moiety selected from the group consisting of chlorine and hydrogen,
- R.sub.3 is a moiety selected from the group consisting of hydrogen and CH.sub.3,
- R.sub.4 is alkylene of up to 5 carbon atoms,
- m and n are each 0 or 1 and m+n is 1 or 2,
- R.sub.5 is alkylene of up to 6 carbon atoms which may be substituted by phenyl,
- Y is a cyclic hydrocarbon radical of 5 or 6 carbon atoms,
- R.sub.6 is a moiety selected from the group consisting of hydrogen, alkyl of up to 8 carbon atoms, cycloalkyl of 3 to 8 carbon atoms, phenyl, tolyl, and acetyl and (p.chloro .alpha.-methylbenzylidene) aminooxyacetyl, and
- R.sub.7 is a moiety selected from the group consisting of hydrogen, alkyl of up to 8 carbon atoms, alkyl of up to 8 carbon atoms substituted with hydroxyl with the proviso that when R.sub.6 and R.sub.7 are each alkyl or hydroxy substituted alkyl, R.sub.6 and R.sub.7 together do not contain more than 10 carbon atoms and
- the acid addition salts thereof with pharmaceutically acceptable acids
- and a liquid or finely divided solid carrier material therefor.
- 2. A method of treating a patient having inflammation and/or pain comprising
- administering to a patient having inflammation and/or pain the pharmaceutical preparation of claim 1.
- 3. The method of claim 2 wherein said compound is administered at a dose of 50 to 1,000 mg daily.
- 4. The preparation of claim 1 wherein said compound is {[(4-chloro-.alpha.-methylbenzylidene)amino]oxy}-acetic acid (2-dimethylamino-ethyl) ester or an acid addition salt thereof with a pharmaceutically acceptable acid.
Priority Claims (2)
Number |
Date |
Country |
Kind |
7008493 |
Jun 1970 |
NLX |
|
7102715 |
Mar 1971 |
NLX |
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Parent Case Info
This is a division of application Ser. No. 972,845, filed Dec. 26, 1978, now U.S. Pat. No. 4,242,348, which is a continuation of Ser. No. 801,030, filed May 27, 1977, now abandoned, which was a division of Ser. No. 509,807, filed Sept. 27, 1974 and now U.S. Pat. No. 4,044,023, which is a division of Ser. No. 151,793, filed June 10, 1971, now U.S. Pat. No. 3,853,955.
US Referenced Citations (2)
Number |
Name |
Date |
Kind |
3692835 |
van Dijk et al. |
Sep 1972 |
|
3803235 |
van Dijk et al. |
Apr 1974 |
|
Divisions (3)
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Number |
Date |
Country |
Parent |
972845 |
Dec 1978 |
|
Parent |
509807 |
Sep 1974 |
|
Parent |
151793 |
Jun 1971 |
|
Continuations (1)
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Number |
Date |
Country |
Parent |
801030 |
May 1977 |
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