Claims
- 1. A method for the treatment of varient angina comprising administering to a patient in need thereof, by a suitable route of administration, an effective amount of a compound of the formula: ##STR3## the optical isomers thereof, and the pharmaceutically acceptable salts thereof, wherein n is 2, 3, or 4, each of R.sup.1, R.sup.2, R.sup.3, and R.sup.4 is independently selected from hydrogen, halogen, trifluoromethyl, C.sub.1-6 alkyl, C.sub.1-6 alkoxy, hydroxy or amino.
- 2. The method of claim 1 wherein said compound is alpha-phenyl-1-(2-phenethyl)-4-piperidine methanol.
- 3. The method of claim 1 wherein said compound is alpha-phenyl-1-(3-phenpropyl)-4-piperidine methanol.
- 4. The method of claim 1 wherein said compound is alpha-(4-methylphenyl)-1-(2-phenethyl)-4-piperidine methanol.
- 5. The method of claim 1 where said compound is alpha-(4-methoxyphenyl)-(2-phenethyl)-4-piperidine methanol.
- 6. The method of claim 1 wherein said compound is alpha-(3,5-dimethylphenyl)-1-(2-phenethyl)-4-piperidine methanol.
- 7. The method of claim 1, wherein said compound is alpha-(3-(trifluoromethyl)phenyl-1-(2-phenethyl)-4-piperidine methanol.
- 8. The method of claim 1, wherein said compound is alpha-(2,3-dimethoxy)-1-(2-phenethyl)-4-piperidine methanol.
- 9. The method of claim 1, wherein said compound is alpha-(3,4-dichlorophenyl)-1-(2-phenylethyl)-4-piperidine methanol.
Parent Case Info
This is a division of Ser. No. 71,524, filed July 7, 1987 which is now U.S. Pat. No. 4,783,471, which was a continuation of application Ser. No. 867,122, filed May 30, 1986 which is now abandoned, which is a continuation-in-part of application Ser. No. 751,419 filed July 2, 1985 which is now abandoned.
US Referenced Citations (9)
Divisions (1)
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Number |
Date |
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Parent |
71524 |
Jul 1987 |
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Continuations (1)
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Number |
Date |
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Parent |
867122 |
May 1986 |
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Continuation in Parts (1)
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Number |
Date |
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Parent |
751419 |
Jul 1985 |
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