Novel Chromatographic Bonded Phase Platform and Methods and Processes

Information

  • NSF Award
  • 9260122
Owner
  • Award Id
    9260122
  • Award Effective Date
    1/1/1993 - 31 years ago
  • Award Expiration Date
    9/30/1993 - 31 years ago
  • Award Amount
    $ 49,965.00
  • Award Instrument
    Standard Grant

Novel Chromatographic Bonded Phase Platform and Methods and Processes

Photo-induced immobilization will be used for the preparation of thin pin-hole free chromatographic surfaces whose silanol sites are inactivated for use in high performance liquid chromatography (HPLC). To demonstrate this chemical platform technology, surfaces will be prepared and chromatographically evaluated using both small and large molecules as standard probes. With judicious selection of monomers, new biofriendly (low non-specific binding) stationary phases can be prepared, allowing selectivity to be influenced by incremental changes in the character and chemical composition of the separation surface. Because the chemical platform is not dependent on specific attachment chemistries, any surface may be employed thereby utilizing certain intrinsic properties beneficial to a specific separation process. Successful completion of Phases I and II will provide the technical foundation for the commercialization of separation products developed and produced by photo-induced crosslinked polymerization not limited to any particular surface type.

  • Program Officer
    Kesh S. Narayanan
  • Min Amd Letter Date
    12/17/1992 - 31 years ago
  • Max Amd Letter Date
    12/17/1992 - 31 years ago
  • ARRA Amount

Institutions

  • Name
    Cohesive Technologies Inc
  • City
    Acton
  • State
    MA
  • Country
    United States
  • Address
    43 Nagog Park, Suite 205
  • Postal Code
    017203426
  • Phone Number
    5082638225

Investigators

  • First Name
    Henry
  • Last Name
    Kolesinski
  • Start Date
    1/1/1993 12:00:00 AM

FOA Information

  • Name
    Industrial Technology
  • Code
    308000
  • Name
    Engineering NEC
  • Code
    59