Claims
- 1. A compound of the formula I: ##STR6## wherein R.sub.1 is a lower alkyl having from 1 to 4 carbon atoms and R is a hydrogen atom or a trifluoroacetyl group, and the hydrochlorides thereof.
- 2. A compound according to claim 1, which is 4-demethoxy-4-hydroxy-11-deoxy-11-methoxy-N-trifluoroacetyldaunomycin.
- 3. A compound according to claim 1, which is 4-demethoxy-4-hydroxy-11-deoxy-11-methoxydaunomycin hydrochloride.
- 4. A pharmaceutical composition comprising a therapeutically effective amount of a compound according to claim 1 and an inert carrier therefor.
- 5. A method of treating a host afflicted with transplanted leukemia P.sub.388 which comprises intraperitoneally administering to said host a compound according to claim 1 in an amount sufficient to inhibit the growth thereof.
Priority Claims (1)
Number |
Date |
Country |
Kind |
18775/77 |
May 1977 |
GBX |
|
Government Interests
The invention described herein was made in the course of work under a grant from the United States Department of Health, Education and Welfare.
US Referenced Citations (3)
Number |
Name |
Date |
Kind |
4025623 |
Arcamone et al. |
May 1977 |
|
4039663 |
Arcamone et al. |
Aug 1977 |
|
4067969 |
Penco et al. |
Jan 1978 |
|