Claims
- 1. A process for the preparation of a compound of the formula ##STR16## wherein R is selected from the group consisting of alkyl of 1 to 12 carbon atoms alkenyl and alkynyl of 2 to 12 carbon atoms and uninterrupted or interrupted with a heteroatom and unsubstituted or substituted with at least one functional groups, cycloalkyl of 3 to 12 carbon atoms unsubstituted or substituted with at least one functional group, aryl of up to 14 carbon atoms and hydrocarbyl aralkyl of up to 18 carbon atoms comprises reacting a compound of the formula ##STR17## in its d, l or dl form and mixtures thereof with an alcohol of the formula
- R--OH III
- wherein R has the above definition to obtain a compound of the formula ##STR18## reacting the latter with a halide of the formula Z-X wherein X is a halogen and Z is R.sub.1 --A--, R.sub.1 is selected from the group consisting of alkyl of 1 to 8 carbon atoms and aryl, A is ##STR19## and R.sub.2 and R.sub.3 are individually alkyl of 1 to 8 carbon atoms to obtain a compound of the formula ##STR20## and reacting the latter with a basic agent to obtain the compound of formula VI.
- 2. The process of claim 1 wherein the compound of formula I is racemic, the compound of formula IV is racemic with the RO-- and --OH having the trans form, the compound of formula V is racemic and the ZO-- and --OR have the trans form and the compound of formula VI is racemic.
- 3. The process of claim 2 wherein R is methyl or ethyl or tert.butyl.
- 4. The process of claim 2 wherein Z is --SO.sub.2 CH.sub.3.
- 5. The process of claim 3 wherein Z is --SO.sub.2 CH.sub.3.
Priority Claims (2)
Number |
Date |
Country |
Kind |
87 0450 |
Jan 1987 |
FRX |
|
87 10792 |
Jul 1987 |
FRX |
|
Parent Case Info
This is a division of Ser. No. 142,534 filed Jan. 7, 1988, now U.S. Pat. No. 4,837,341.
US Referenced Citations (1)
Number |
Name |
Date |
Kind |
4556732 |
Martel et al. |
Dec 1985 |
|
Foreign Referenced Citations (1)
Number |
Date |
Country |
0041283 |
Dec 1981 |
EPX |
Divisions (1)
|
Number |
Date |
Country |
Parent |
142534 |
Jan 1988 |
|