Claims
- 1.-3. (Cancelled)
- 4. An isolated polypeptide comprising the amino acid sequence of SEQ ID NO:2.
- 5. An antibody having immunospecificity for the polypeptide sequence of SEQ ID NO:2.
- 6. A process for identifying a compound useful for the treatment of low white blood cell count in a patient, comprising contacting a NHP preparation with said compound for a time sufficient to allow the compound to interact with or bind to the NHP preparation, and determining whether said compound inhibits the activity of the NHP preparation.
- 7. The process of claim 6, wherein said NHP preparation comprises an isolated NIP protein, polypeptide or peptide.
- 8. The process of claim 6, wherein said NHP preparation comprises a recombinant cell that expresses a NHP protein, polypeptide, or peptide.
- 9. The process of claim 6, wherein said NHP preparation comprises a transgenic nonhuman animal that expresses a human NHP protein, polypeptide or peptide.
- 10. The process of claim 6, wherein said NHP preparation comprises a human NHP protein, polypeptide, or peptide.
- 11. A process for treating low white blood cell count, in a mammal in need of such treatment, comprising administering a therapeutically effective amount of a compound that inhibits NHP activity to said mammal.
- 12. The process of claim 11, wherein said mammal is a human.
- 13. A method for selectively inhibiting NHP activity in a human patient, comprising administering a compound that selectivity of a NHP protein, polypeptide or peptide in said patient, wherein the activity of the compound does not result in significant toxic side effects in said patient.
- 14. The method of claim 13, wherein the inhibition of the NHP protein, polypeptide or peptide increases white blood cell count in said patient.
Parent Case Info
[0001] The present application is a continuation-in-part of co-pending U.S. application Ser. No. 09/653,839, filed on Sep. 1, 2000, which claims the benefit of U.S. Provisional Application Serial No. 60/152,057, filed Sep. 2, 1999, both of which are herein incorporated by reference in their entirety.
Provisional Applications (1)
|
Number |
Date |
Country |
|
60152057 |
Sep 1999 |
US |
Divisions (1)
|
Number |
Date |
Country |
Parent |
10202619 |
Jul 2002 |
US |
Child |
10760709 |
Jan 2004 |
US |
Continuation in Parts (1)
|
Number |
Date |
Country |
Parent |
09653839 |
Sep 2000 |
US |
Child |
10202619 |
Jul 2002 |
US |