Novel intermediate compound for the preparation of prostaglandin F analogue

Abstract

A method for the preparation of a prostaglandin F analogue presented by the following formula (I):

Description

Claims

1. A method for preparing a compound represented by the following formula (I):

2. The method of claim 1, wherein the compound represented by formula (7), the compound represented by formula (8), or the mixture of both is prepared by the following steps: (a) reacting a compound represented by the following formula (2):

3. The method of claim 1, wherein R1 is hydrogen or isopropyl group.

4. The method of claim 1, wherein G is selected from a group consisting of:

5. The method of claim 1, wherein the formula (I) is:

6. A compound represented by the following formula (7) or (8):

7. The compound of claim 6, wherein the compound represented by formula (7) is a compound represented by the following formula (7a):

8. The compound of claim 6, wherein the compound represented by formula (8) is a compound represented by the following formula (8a):

9. A compound represented by the following formula (9) or (10):

10. The compound of claim 9, wherein the compound represented by formula (9) is a compound represented by the following formula (9a):

11. The compound of claim 9, wherein the compound represented by formula (10) is a compound represented by the following formula (10a):