Claims
- 1. An isolated nucleic acid molecule comprising a nucleic acid sequence encoding a polypeptide comprising an amino acid sequence selected from the group consisting of:
a) a mature form of the amino acid sequence of SEQ ID NO: 20; b) a variant of a mature form of the amino acid sequence of SEQ ID NO: 20 wherein any amino acid in the mature form of the chosen sequence is changed to a different amino acid, provided that no more than 15% of the amino acid residues in the sequence of the mature form are so changed; c) the amino acid sequence of SEQ ID NO: 20; d) a variant of the amino acid sequence of SEQ ID NO: 20, in which any amino acid specified in the chosen sequence is changed to a different amino acid, provided that no more than 15% of the amino acid residues in the sequence are so changed; e) a nucleic acid fragment encoding at least a portion of a polypeptide comprising the amino acid sequence of SEQ ID NO: 20 or any variant of said polypeptide wherein any amino acid of the chosen sequence is changed to a different amino acid, provided that no more than 10% of the amino acid residues in the sequence are so changed; and f) the complement of any of said nucleic acid molecules.
- 2. The nucleic acid molecule of claim 1, wherein the nucleic acid molecule comprises the nucleotide sequence of a naturally occurring allelic nucleic acid variant.
- 3. The nucleic acid molecule of claim 2 that encodes a variant polypeptide, wherein the variant polypeptide has the polypeptide sequence of a naturally occurring polypeptide variant.
- 4. The nucleic acid molecule of claim 1, wherein the nucleic acid molecule comprises a single nucleotide polymorphism encoding said variant polypeptide.
- 5. The nucleic acid molecule of claim 1, wherein said nucleic acid molecule comprises a nucleotide sequence selected from the group consisting of
a) the nucleotide sequence of SEQ ID NO: 19; b) a nucleotide sequence wherein one or more nucleotides in the nucleotide sequence of SEQ ID NO: 19 is changed from that selected from the group consisting of the chosen sequence to a different nucleotide provided that no more than 15% of the nucleotides are so changed; c) a nucleic acid fragment of the sequence of SEQ ID NO: 19; and d) a nucleic acid fragment wherein one or more nucleotides in the nucleotide sequence of SEQ ID NO: 19 is changed from that selected from the group consisting of the chosen sequence to a different nucleotide provided that no more than 15% of the nucleotides are so changed.
- 6. The nucleic acid molecule of claim 1, wherein said nucleic acid molecule hybridizes under stringent conditions to the nucleotide sequence of SEQ ID NO: 19, or a complement of said nucleotide sequence.
- 7. The nucleic acid molecule of claim 1, wherein the nucleic acid molecule comprises a nucleotide sequence in which any nucleotide specified in the coding sequence of the chosen nucleotide sequence is changed from that selected from the group consisting of the chosen sequence to a different nucleotide provided that no more than 15% of the nucleotides in the chosen coding sequence are so changed, and an isolated second polynucleotide that is a complement of the first polynucleotide.
- 8. A vector comprising the nucleic acid molecule of claim 7.
- 9. The vector of claim 8, further comprising a promoter operably linked to said nucleic acid molecule.
- 10. A cell comprising the vector of claim 10.
- 11. A composition comprising the nucleic acid molecule of claim 1 and an acceptable carrier.
- 12. A kit comprising in one or more containers, the composition of claim 11.
RELATED APPLICATIONS
[0001] This application is a divisional application of U.S. Ser. No. 09/813,432, filed Mar. 20, 2001, which claims priority to U.S. Ser. No. 60/190,835, filed Mar. 20, 2000 (15966-729); U.S. Ser. No. 60/190,768, filed Mar. 20, 2000 (15966-734); U.S. Ser. No. 60/190,972, filed Mar. 22, 2000 (15966-735); U.S. Ser. No. 60/191,199, filed Mar. 22, 2000 (15966-737); U.S. Ser. No. 60/191,947, filed Mar. 24, 2000 (15966-738); U.S. Ser. No. 60/192,665, filed Mar. 28, 2000 (15966-739); U.S. Ser. No. 60/192,657, filed Mar. 28, 2000 (15966-740); U.S. Ser. No. 60/192,984, filed Mar. 28, 2000 (15966-741); U.S. Ser. No. 60/192,664), filed Mar. 28, 2000 (15966-742); U.S. Ser. No. 60/192,836, filed Mar. 29, 2000 (15966-743), and U.S. Ser. No. 60/193,843, filed Mar. 31, 2000 (15966-741A), which are incorporated herein by reference in their entirety.
Provisional Applications (11)
|
Number |
Date |
Country |
|
60190835 |
Mar 2000 |
US |
|
60190768 |
Mar 2000 |
US |
|
60190972 |
Mar 2000 |
US |
|
60191199 |
Mar 2000 |
US |
|
60191947 |
Mar 2000 |
US |
|
60192665 |
Mar 2000 |
US |
|
60192657 |
Mar 2000 |
US |
|
60192984 |
Mar 2000 |
US |
|
60192664 |
Mar 2000 |
US |
|
60192836 |
Mar 2000 |
US |
|
60193843 |
Mar 2000 |
US |
Divisions (1)
|
Number |
Date |
Country |
Parent |
09813432 |
Mar 2001 |
US |
Child |
10689832 |
Oct 2003 |
US |