TREA

Nuclear molecular imaging contrast agent

Follow

Information

  • Patent Application
  • 20070154390
  • Publication Number
    20070154390
  • Date Filed
    June 09, 2006
    18 years ago
  • Date Published
    July 05, 2007
    17 years ago
Information
Abstract
A nuclear molecular imaging contrast agent. The nuclear imaging contrast agent comprises a polymer according to the structure of
Description
Claims
  • 1. A nucleus molecular imaging contrast agent, comprising polymers with structures as formula (I), formula, (II):
  • 2. The nucleus molecular imaging contrast agent as claimed in claim 1, wherein D comprises 2,2-dihydroxymethyl propanoic acid and residual groups of the derivative thereof.
  • 3. The nucleus molecular imaging contrast agent as claimed in claim 1, wherein D is
  • 4. The nucleus molecular imaging contrast agent as claimed in claim 3, wherein D is
  • 5. The nucleus molecular imaging contrast agent as claimed in claim 3, wherein D is
  • 6. The nucleus molecular imaging contrast agent as claimed in claim 1, wherein L is a radioisotope.
  • 7. The nucleus molecular imaging contrast agent as claimed in claim 6, wherein L is In-111.
  • 8. The nucleus molecular imaging contrast agent as claimed in claim 6, wherein L is Gd-153.
  • 9. The nucleus molecular imaging contrast agent as claimed in claim 1, wherein the analyte-specific moiety is a folic acid group.
  • 10. The nucleus molecular imaging contrast agent as claimed in claim 1, wherein the analyte-specific moiety is a glucose group.
  • 11. The nucleus molecular imaging contrast agent as claimed in claim 1, wherein the analyte-specific moiety is an amino acid group.
  • 12. The nucleus molecular imaging contrast agent as claimed in claim 1, wherein the analyte-specific moiety is a deoxyibouncleic acid group.
  • 13. The nucleus molecular imaging contrast agent as claimed in claim 1, wherein Z comprises a metal-chelated group.
  • 14. The nucleus molecular imaging contrast agent as claimed in claim 1, wherein Z comprises a residual group of ethylenedinitrilo tetraacetic acid (EDTA) or a residual group of ethylenediimino dibyric acid (EDBA).
  • 15. The nucleus molecular imaging contrast agent as claimed in claim 9, wherein Z is a residual group of diethylene triaminepentaacetic acid (DTPA).
Priority Claims (1)
Number Date Country Kind
94147660 Dec 2005 TW national