Claims
- 1. A composition comprising 1,2-bis(oleoyloxy)-3-(4′-trimethylammnio)propane (DOTAP), dioleoylphosphatidylethanolamine (DOPE)dilauroylphosphatidylethanolamine (DLPE), and wherein the ratio of DOTAP to phospolipids is appoximately 1:1 and wherein the ratio of DOPE to DLPE is 100:1 to 1:100.
- 2. The composition of claim 1, wherein the ratio of DOPE to DLPE is approximately 9:1.
- 3. The composition of claim 1, wherein the ratio of DOPE to DLPE is approximately 19:1.
- 4. A composition comprising DOTAP, DOPE, and DLPC wherein the ratio of DOTAP to neutral lipids is approximately 1:1 and wherein the ratio of DOPE to DLPC is 100:1 to 1:100.
- 5. The composition of claim 4, wherein the ratio of DOPE to DLPC is approximately 9:1.
- 6. A composition comprising 1,4-bis(3-oleoylamidopropyl)piperazine, histone H1, and detergent, wherein the ratio of 1,4-bis(3-oleoylamidopropyl)piperazine to histone H1 is 3 to 1, and wherein the ratio of 1,4-bis(3-oleoylamidopropyl)piperazine to detergent is 100:1 to 1:100.
- 7. The composition of claim 6, wherein said detergent comprises DLPE.
- 8. The composition of claim 6, wherein said detergent comprises 3-[(cholamidopropyl)dimethylammonio]-1-propanesulfonate (CHAPS).
- 9. The composition of claim 7, wherein the ratio of 1,4-bis(3-oleoylamidopropyl)piperazine to histone H1 to DLPE is 3:1:0.125.
- 10. The composition of claim 8 wherein the ratio of 1,4-bis(3-oleoylamidopropyl)piperazine to histone H1 to CHAPS is 3:1:0.25.
Parent Case Info
This application claims priority benefit of U.S. Provisional Application Serial No. 60/165,211, filed Nov. 12, 1999.
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Provisional Applications (1)
|
Number |
Date |
Country |
|
60/165211 |
Nov 1999 |
US |