Patent Application
20210315930
This invention relates to nutraceutical compositions, products and methods that include multimodal prophylaxis against and treatment of viral and bacterial infections and inflammations, especially in human beings.
Before modern pharmaceuticals, mankind depended on natural substances for medical purposes which included, but were not limited to, relieving pain, enhancing sexual and other performance, enhancing sleep, enhancing bowel function, healing wounds, decreasing respiratory difficulty, stopping blood loss, halting the progress of illness and augmenting general wellbeing. Such natural substances included but were not limited to vegetables, herbs, roots, flowers, tree barks and certain animal organs and tissues. A key target of the use of natural substances was abatement of the combination of pain, swelling and redness in any area of the body, a combination which by the 16th century came to be known as inflammation. At that time and before, inflammation was an important target for treatment with natural substances because it was well recognized that inflammation could progress to worse morbidity or death. Although allergic or purely traumatic injury can also cause inflammation, in the 19th century it was discovered that bacterial infection was a chief and more dangerous cause. In the 20th century, knowledge of the causes of inflammation expanded to include viral and fungal infections.
In our time, natural substances have evolved to include isolated atoms known as minerals, isolated biomolecules known as vitamins and purified extracts from any of the above mentioned, historical sources of natural substances. There is a large variety of such modern natural substances, which in modern pill, tablet, liquid, powder or capsule form are now known as dietary or health supplements, or nutraceuticals. Nutraceuticals are currently used for essentially the same array of purposes as those throughout history, but now also for fortification of the immune system against primary acquisition of infection, i.e. prophylaxis, and for fortification of the immune system's ability to defeat infection once it is established.
Modern antibacterial and antiviral vaccines are generally effective against only the bacterial or viral pathogen from which they were pharmaceutically derived, not a range of bacteria or viruses. A small variety of available supplements is targeted at overall fortification of the immune system, with the intent to prevent or mollify a variety of viral and bacterial infections such that no infection occurs, or its symptoms and physiologic effects are minimal and brief. These supplements go by such labels as Immune Boost, Immune Health and others, and many if not most are composed of a single active ingredient, and none claims both immune fortification and inclusion of a known anti-inflammatory substance.
What is needed is a novel and optimal combination of immune fortifying ingredients, each of which works by a different mechanism to prevent, mollify and treat a wide range of viral and bacterial infections (hereafter termed wide-spectrum anti-infectious), and another ingredient or ingredients which is/are anti-inflammatory, in the event that some degree of infectious inflammation becomes established.
What is needed is a novel and unique combination of nutraceuticals whose wide-spectrum prophylactic effect against infection is compounded by its ability to treat already established infection and infectious inflammation, such that its overall therapeutic effect equals more than the sum of its parts, as does the fortuitous combination of vitamin C+thiamine+hydrocortisone in reversal of sepsis, a severely life-threatening condition which can follow routine infection with a virus or bacterium.
A novel combination of vitamin, mineral and herbal or other natural, organic supplements (nutraceuticals) for protection against a wide spectrum of viral and bacterial infections, and for treatment of established infection and infectious inflammation. The composition of supplements is to be compounded as a pill, tablet, powder, capsule or liquid to be taken orally one more times per day, or as parenteral liquid.
Among the possible anti-infectious vitamins to be used are vitamins C and E. The mineral to be used is zinc complexed with citrate, or the amino acid methionine, or other cofactor, in order to increase zinc's bioavailability.
Nutraceuticals provided herein as immune boosters and/or antiviral agents are useful for accelerating wound healing and improved immune function. Among the possible anti-infectious herbs or other organic substances to be used are Echinacea purpura, fulvic acid, ginger, taurine, α-lipoic acid, r-lipoic acid, black elderberry extract, sage, Cat's Claw extract (Uncaria tomentosa) and the omega-3 fatty acids, DHA and EPA.
Among the possible anti-inflammatory herbs or other organic anti-Inflammatory substances to be used are Boswellia serrata gum resin, green tea extract, pycnogenol, resveratrol, curcuminoids and the omega-3 fatty acids, DHA and EPA. Methods of using these compositions of vitamins, minerals, herbs and other organic substances and compositions are also disclosed herein. The amount of each individual supplement substance may be varied significantly.
An object of the invention is to provide compositions of nutraceuticals to fortify the human or companion animal immune system in a way that prevents a wide spectrum of known or new strains of viruses and bacteria from starting a new infection in the host.
Another object of the invention is to provide compositions of nutraceuticals to fortify the human or companion animal immune system in a way that permits nascent viral or bacterial infection, once established, to be treated and defeated before the infection can cause serious and/or widespread systemic symptoms and effects, or to minimize such symptoms to a life non-threatening level.
Another object of the invention is to provide compositions of nutraceuticals that prevent or limit inflammation, especially in the lungs, in which virally or bacterially induced inflammation causes arteriolar and capillary leakage and resultant pulmonary edema, excess mucus secretion, possible severe bronchoconstriction and, in the worst case, acute respiratory distress syndrome (ARDS) with airway collapse, any of which phenomena can compromise pulmonary function to the point of fatal respiratory failure.
Another object of the invention is to prevent or limit development of virally induced secondary bacterial infection/inflammation, or vice versa, especially in the lungs. An overall object of the invention is to help flatten the viral epidemic curve of yearly Influenza, and that of any new viral epidemic. Other features and advantages of the present invention will become apparent to those of skill in the art to consideration of the ensuing description and the appended claims.
For the purposes of this specification, the word “nutraceutical”, refers to a food item, or a part of a food item, that offers medical health benefits, including prevention and/or treatment of disease. More particularly, a nutraceutical is a material that is:
Examples of a biologically active process material may include a finely chopped, powdered, pure read, or cook material derived from plant or animal tissue, or an extract of plant or animal tissue. The immune boosters and or antiviral agents by first class of nutraceuticals. These agents are useful for accelerating improved immune function; and they include extracts from the cone flowers or herbs of the genus Echinacea and mixtures thereof. Zinc and its bioactive salts such as zinc acetate also act as immune boosters in the treatment of the common cold and viral infections.
A novel and unique combination of vitamin, mineral and herbal/organic supplements (nutraceuticals) in one formulary forming one or more compositions and methods for the purpose of fortifying the innate (cellular) and adaptive (hormonal) components of the immune system against bacterial and viral infection, and their propagation, transmission and effects.
Also included in the formulary compositions are two or more natural, herbal or other organic anti-inflammatory substances for the suppression of tissue inflammation, especially in the lungs. The formulary thereby provides multimodal nutraceutical protection against acquisition of infection and against deleterious effects of inflammation in the lungs. The formulary is available in both oral and parenteral forms.
In a preferred embodiment, the formulary composition contains:
Any of the listed anti-infectious nutraceuticals permutated with any of the listed anti-inflammatory and, in term, combined with the Zinc and Vitamin C or E, will confer five levels of anti-infectious protection, including white blood cell fortification and activation, virucidal-bactericidal activity, enhancement of antibody production, anti-oxidant activity and anti-inflammatory activity. The oral formulary, capsule or other, is enteric-coated to prevent breakdown by gastric acid and permit delivery of unaltered nutraceuticals to the duodenum for absorption.
Although the present invention has been described in detail with particular reference in preferred embodiments thereof, it should be understood that the invention is capable of other different embodiments, and its details are capable of modifications in various obvious respects. As is readily apparent to those skilled in the art, variations and modifications can be affected while remaining within the spirit and scope of the invention. Accordingly, the foregoing disclosure description is for illustrative purposes only and do not any way limit the invention which is defined only by the claims.
