Patent Application
20210025796
The present application relates to irradiation technologies, radiation technologies, rotator technologies, temperature regulation technologies, x-ray tube technologies, and more particularly, to an on-axis, angled, rotator for x-ray irradiation and methods of using the on-axis, angled, rotator for x-ray irradiation.
In the world of photon sterilization, uniformity and dose rate of radiation are critical in achieving successful sterilization. For the purposes of this disclosure, uniformity may be the ratio of the highest dose of radiation to the lowest dose of radiation emitted from a radiation device, such as an x-ray tube. Typically, increasing the highest dose comes at the expense of the lowest dose and vice versa. As a result, high dose and uniformity, such as when irradiating various types of samples, is often difficult to achieve. Notably, position in a radiation field is very important to the rate and uniformity of the exposure dose that a particular sample receives from a radiation device. Radiation devices, such as x-ray tubes, suffer from an anode heel effect and do not distribute radiation uniformly in their perpendicular plane. For example, in currently existing applications, samples may be positioned in front of the incident radiation window of the radiation device, and, as a result, the samples must be held far away from the origin of the radiation (e.g. the radiation device) to create an even distribution of photon dose across the exposed side of the sample. The sample's distance away from the origin of the radiation causes a drop in the amount of dose that the sample receives and increases the total exposure time a sample needs to accumulate large doses. As a result, this makes it very difficult for an x-ray tube or other radiation device to create highly uniform fields with a high dose rate and limits a radiation device's viability for applications, such as, but not limited to, virus deactivation and x-ray sterilization.
Another issue with existing technologies is that certain irradiation applications require temperature control, such as cooling. Notably, existing irradiation technologies are unable to compensate for uniformity, dosage rate, and temperature regulation. Additionally, currently existing technologies are not readily useable with different radiation devices, unless there are substantial modifications that are made to adapt the technology with each different radiation device. While current technologies provide for many benefits and efficiencies, these technologies can be substantially improved and enhanced. In particular, current technologies may be improved so as to provide increased uniformity of radiation exposure, increased radiation dosage rates, and increased temperature control. Such enhancements and improvements to methodologies and technologies may provide for increased efficiency, increased effectiveness, reduced costs, and increased ease-of-use.
A system and accompanying methods for providing an on-axis, angled, rotator device for x-ray irradiation are disclosed. In particular, the system and methods take advantage of the discovery that when an object is angled between 0 and 180 degrees in a perpendicular irradiation plane of a radiation device, the geometric limitations of the radiation device (e.g. x-ray tube) are reduced dramatically. Such geometric limitations may be further reduced by rotation of a sample along the sample's center axis. By angling and rotating a sample in the radiation field (e.g. an x-ray field) of the radiation device, the sample may be held close to the radiation device (i.e. at a high dosage rate zone of the radiation field) without sacrificing radiation exposure uniformity. In certain embodiments, the system and methods utilize the positioning in conjunction with reflective material (e.g. reflective material and technology as provided in U.S. Pat. No. 6,389,099) to create an advanced rotation mechanism that positions samples and rotates the samples in place. By doing so, uniformity of radiation exposure and dosage rate is maximized by using the rotator device, which complements the photon output geometry of any radiation device, such as an x-ray tube.
Notably, the mechanisms, positioning and/or motion provided by the system and methods may be readily adapted to any radiation device manufacturer's device (e.g. x-ray tube devices). Additionally, the system and methods facilitate temperature control of the samples via the rotator device. For example, the dry ice (or another suitable substance) may be placed into various portions of the rotator device to keep the samples that are rotating in the rotator device chilled. In certain embodiments, the rotator device may be equipped with a heating element to keep samples warm if so desired. Notably, the angled geometry provided by the system and methods via the rotator device also allows for more efficient sample placement so that more samples may benefit from the high uniform dose compared to the conventional method, which involves laying the samples flat. In certain additional embodiments, a sample may be angled between two or more sources of radiation and may benefit from complementing the tube geometries.
In one embodiment, a system for providing an on-axis, angled, rotator for x-ray irradiation is provided. The system may include a memory that stores instructions and a processor that executes the instructions to perform various operations of the system. The system may perform an operation that includes facilitating positioning of a vial (tubes, containers, and/or other devices capable of storing samples) containing a sample into a slot of a container of a rotator device. In certain embodiments, an angle of the slot of the container may be between 0 and 180 degrees relative to a perpendicular irradiation plane of a radiation device. The system may then perform an operation that includes facilitating positioning of a cup into the container of the rotator device. In certain embodiments, the cup may contact the vial when the cup is positioned in the container and the vial containing the sample is positioned in the slot. In certain embodiments, the cup may contact the vial via an O-ring or other similar component positioned on a surface of the cup. The system may proceed to perform an operation that includes facilitating positioning of the rotator device within range of a radiation field of the radiation device. Furthermore, the system may perform an operation that includes facilitating the transmission of torque to the cup, such as via a driveshaft of the rotator device. In certain embodiments, the torque may cause the cup to rotate, thereby causing the cup to rotate the vial containing the sample about a center axis of the vial containing the sample. Notably, the angle of the slot and the rotation of the sample about the center axis may facilitate uniform radiation exposure to the sample in the vial when the radiation device emits radiation.
In another embodiment, an on-axis, angled, rotator device is disclosed. The rotator device may include a container containing a slot for receiving a sample. An angle of the slot of the container may be configured to be between 0 and 180 degrees relative to a perpendicular irradiation plane of a radiation device. The rotator device may also include a cup configured to be positioned within an opening of the container and configured to contact the sample when the sample is contained in the slot. Additionally, the rotator device may include a driveshaft configured to transmit torque to cause the cup to be rotated when the cup is positioned within the opening of the container. Notably, when the sample resides within the slot and the driveshaft transmits the torque to the cup, the cup may cause the sample to rotate about a center axis of the sample. Furthermore, the angle of the slot containing the sample and the rotation of the sample about the center axis may facilitate uniform radiation exposure to the sample when the radiation device emits radiation.
In another embodiment, a method for utilizing an on-axis, angled, rotator device is provided. In certain embodiments, the method may include utilizing a memory that stores instructions, and a processor that executes the instructions to perform the various functions of the method. In certain embodiments, a human may facilitate some or all of the steps of the method. The method may include positioning a vial containing a sample into a slot of a container of a rotator device. In certain embodiments, an angle of the slot of the container may be between 0 and 180 degrees relative to a perpendicular irradiation plane of a radiation device. The method may then include positioning a cup into the container. The cup may contact the vial when the cup is positioned in the container and the vial containing the sample is positioned in the slot. Additionally, the method may include positioning the rotator device within range of a radiation field of the radiation device. Furthermore, the method may include transmitting, via a driveshaft of the rotator device, torque to the cup. The torque may cause the cup to rotate, thereby causing the cup to rotate the vial containing the sample about a center axis of the vial containing the sample. The angle of the slot and the rotation of the sample about the center axis may facilitate uniform radiation exposure to the sample in the vial when the radiation device emits radiation.
In yet another embodiment, another on-axis, angled, rotator device is disclosed. The device may include a first container containing a slot for receiving a sample. In certain embodiments, an angle of the slot of the container is between 0 and 180 degrees relative to a perpendicular irradiation plane of a radiation device. The device may also include a second container configured to be positioned within the first container and configured to contact the sample when the sample is contained in the slot. The device may further include a driveshaft configured to transmit torque to the second container to cause the second container to rotate. When the sample resides within the slot and the second container rotates, the rotation of the second container may cause the sample to rotate about a center axis of the sample. The angle of the slot containing the sample and the rotation of the sample about the center axis may facilitate uniform radiation exposure to the sample when the radiation device emits radiation.
According to yet another embodiment, another device is provided. The device may include a radiation device configured to emit radiation. In certain embodiments, the radiation device may be part of the device or separate from the device. The device may also include a container, a first tube (e.g. vial) positioned in the container and for receiving a first sample, and a second tube positioned in the container and for receiving a second sample. In certain embodiments, the second tube may be positioned adjacent to the first tube and may face a direction opposing the first tube. In certain embodiments, the first tube and the second tube may be positioned at angles relative to a perpendicular irradiation plane of the radiation device such that uniform radiation exposure to the first and second samples may occur when the radiation device emits radiation towards the container of the device.
These and other features of the systems and methods for providing an on-axis, angled, rotator for x-ray irradiation are described in the following detailed description, drawings, and appended claims.
A system 100 and accompanying methods for providing an on-axis, angled, rotator 200 for x-ray irradiation are disclosed. In particular, the system 100 and methods take advantage of the discovery that when an object is angled between 0 and 180 degrees in a perpendicular irradiation plane of a radiation device 800, the geometric limitations of the radiation device 800 (e.g. x-ray tube) may be reduced dramatically. Such geometric limitations may be further reduced by rotation of a sample along the sample's center axis. By angling and rotating a sample in the radiation field (e.g. an x-ray field) of the radiation device 800, the sample may be held close to the radiation device 800 (i.e. at a high dosage rate zone of the radiation field) without sacrificing radiation exposure uniformity. In certain embodiments, the system 100 and methods utilize the positioning in conjunction with reflective material (e.g. reflective material and technology as provided in U.S. Pat. No. 6,389,099) to create an advanced rotation mechanism that positions samples and rotates the samples in place. By doing so, uniformity of radiation exposure and dosage rate is maximized by using the rotator device 200, which may complement the photon output geometry of any radiation device, such as an x-ray tube.
Notably, the mechanisms, positioning and/or motion provided by the system 100 and methods may be readily adapted to any radiation device manufacturer's device. Additionally, the system 100 and methods facilitate temperature control of the samples via the rotator device 200 itself. For example, the dry ice (or another suitable substance) may be placed into various portions of the rotator device 200 to keep the samples that are rotating in the rotator device 200 at a desired temperature. In certain embodiments, the rotator device 200 may be equipped with a heating element to keep samples warm if desired. Notably, the angled geometry provided by the system 100 and methods via the rotator device 200 also allows for more efficient sample placement so that more samples may benefit from the high uniform dose compared to the conventional method, which involves laying the samples flat. In certain additional embodiments, a sample may be angled between two or more sources of radiation and may benefit from complementing the tube geometries.
Still further, the system 100 and methods utilize the rotator device 200 to hold samples, such as, but not limited to, vials, tubes, medical implants, and/or containers at an angle that complements the geometry of a radiation device's 800 radiation output. Mechanisms of the rotator device 200 may also rotate the samples along their individual center axes so that the photon exposure to the samples is even throughout the samples themselves. The goal is to facilitate the creation of a dose rate at the center of the sample that is as close to the dose rate at the surface as possible. In certain embodiments and as indicated above, the rotator device 200 may enable temperature control of the samples to be irradiated by the radiation device 800, which can allow for hot, cold, or other temperature insulation. In certain embodiments, the rotator device 200 may place certain or all samples at an angle relative to the radiation device 800 so that cooler photon emission areas are closer in proximity and hotter photon emission areas are further in proximity. This may compensate for any geometry of the radiation device 800 itself, and may thus allow for more uniform doses from the radiation device 800 without sacrificing dosing rate.
As shown in
Notably, the system 100 may include a first user 101, who may utilize a first user device 102 to access data, content, and services, or to perform a variety of other tasks and functions. As an example, the first user 101 may utilize first user device 102 to transmit signals to access various online services and content, such as those available on an internet, on other devices, and/or on various computing systems. In certain embodiments, the first user 101 may be an individual that may seek to irradiate samples of food, viruses, bacteria, medical devices, blood, cannabis, plants, cells, cosmetics, agricultural products, packaging, any object, any substance, or a combination thereof. In certain embodiments, the first user 101 may be a robot, a computer, a program, a process, any type of user, or any combination thereof. The first user device 102 may include a memory 103 that includes instructions, and a processor 104 that executes the instructions from the memory 103 to perform the various operations that are performed by the first user device 102. In certain embodiments, the processor 104 may be hardware, software, or a combination thereof. The first user device 102 may also include an interface 105 (e.g. screen, monitor, graphical user interface, etc.) that may enable the first user 101 to interact with various applications executing on the first user device 102 and to interact with the system 100. In certain embodiments, the first user device 102 may be and/or may include a computer, any type of sensor, a laptop, a set-top-box, a tablet device, a phablet, a server, a mobile device, a smartphone, a smart watch, and/or any other type of computing device. Illustratively, the first user device 102 is shown as a smartphone device in
In addition to using first user device 102, the first user 101 may also utilize and/or have access to additional user devices. As with first user device 102, the first user 101 may utilize the additional user devices to transmit signals to access various online services and content. The additional user devices may include memories that include instructions, and processors that executes the instructions from the memories to perform the various operations that are performed by the additional user devices. In certain embodiments, the processors of the additional user devices may be hardware, software, or a combination thereof. The additional user devices may also include interfaces that may enable the first user 101 to interact with various applications executing on the additional user devices and to interact with the system 100. In certain embodiments, the additional user devices may be and/or may include a computer, any type of sensor, a laptop, a set-top-box, a tablet device, a phablet, a server, a mobile device, a smartphone, a smart watch, and/or any other type of computing device, and/or any combination thereof.
The first user device 102 and/or additional user devices may belong to and/or form a communications network. In certain embodiments, the communications network may be a local, mesh, or other network that enables and/or facilitates various aspects of the functionality of the system 100. In certain embodiments, the communications network may be formed between the first user device 102 and additional user devices through the use of any type of wireless or other protocol and/or technology. For example, user devices may communicate with one another in the communications network by utilizing any protocol and/or wireless technology, satellite, fiber, or any combination thereof. Notably, the communications network may be configured to communicatively link with and/or communicate with any other network of the system 100 and/or outside the system 100.
In certain embodiments, the first user device 102 and additional user devices belonging to the communications network may share and exchange data with each other via the communications network. For example, the user devices may share information relating to the various components of the user devices, information identifying the locations of the user devices, information indicating the types of sensors that are contained in and/or on the user devices, information identifying the applications being utilized on the user devices, information identifying how the user devices are being utilized by a user, information identifying an orientation of the user devices and/or the vials/tubes held in the rotator device 200, information identifying user profiles for users of the user devices, information identifying device profiles for the user devices, information identifying the number of devices in the communications network, information identifying devices being added to or removed from the communications network, any other information, or any combination thereof.
In addition to the first user 101, the system 100 may also include a second user 110, who may utilize a second user device 111 to perform a variety of functions. For example, the second user device 111 may be utilized by the second user 110 to transmit signals to request various types of content, services, and data provided by and/or accessible by communications network 135 or any other network in the system 100. In certain embodiments, the second user 110 may be an individual that may seek to irradiate food, viruses, bacteria, medical devices, blood, cannabis, plants, cells, cosmetics, agricultural products, packaging, any object, any substance, or a combination thereof. In further embodiments, the second user 110 may be a robot, a computer, a program, a process, any type of user, or any combination thereof. The second user device 111 may include a memory 112 that includes instructions, and a processor 113 that executes the instructions from the memory 112 to perform the various operations that are performed by the second user device 111. In certain embodiments, the processor 113 may be hardware, software, or a combination thereof. The second user device 111 may also include an interface 114 (e.g. screen, monitor, graphical user interface, etc.) that may enable the second user 110 to interact with various applications executing on the second user device 111 and to interact with the system 100. In certain embodiments, the second user device 111 may be a computer, a laptop, a set-top-box, a tablet device, a phablet, a server, a mobile device, a smartphone, a smart watch, and/or any other type of computing device. Illustratively, the second user device 111 is shown as a tablet device in
In certain embodiments, the first user device 102, the additional user devices, and/or the second user device 111 may have any number of software applications and/or application services stored and/or accessible thereon. For example, the first user device 102, the additional user devices, and/or the second user device 111 may include applications for controlling the rotator device 200, applications for controlling the radiation device 800, applications for controlling any device of the system 100, interactive social media applications, biometric applications, cloud-based applications, VoIP applications, other types of phone-based applications, product-ordering applications, business applications, e-commerce applications, media streaming applications, content-based applications, media-editing applications, database applications, gaming applications, internet-based applications, browser applications, mobile applications, service-based applications, productivity applications, video applications, music applications, social media applications, any other type of applications, any types of application services, or a combination thereof. In certain embodiments, the software applications may support the functionality provided by the system 100 and methods described in the present disclosure. In certain embodiments, the software applications and services may include one or more graphical user interfaces so as to enable the first and second users 101, 110 to readily interact with the software applications. The software applications and services may also be utilized by the first and second users 101, 110 to interact with any device in the system 100, any network in the system 100, or any combination thereof. In certain embodiments, the first user device 102, the additional user devices, and/or the second user device 111 may include associated telephone numbers, device identities, or any other identifiers to uniquely identify the first user device 102, the additional user devices, and/or the second user device 111.
The system 100 may also include a communications network 135. The communications network 135 may be under the control of a service provider, the first user 101, the second user 110, any other designated user, a computer, another network, or a combination thereof. The communications network 135 of the system 100 may be configured to link each of the devices in the system 100 to one another. For example, the communications network 135 may be utilized by the first user device 102 to connect with other devices within or outside communications network 135, such as, but not limited to, the radiation device 800 and/or the rotator device 200. Additionally, the communications network 135 may be configured to transmit, generate, and receive any information and data traversing the system 100. In certain embodiments, the communications network 135 may include any number of servers, databases, or other componentry. The communications network 135 may also include and be connected to a mesh network, a local network, a cloud-computing network, an IMS network, a VoIP network, a security network, a VoLTE network, a wireless network, an Ethernet network, a satellite network, a broadband network, a cellular network, a private network, a cable network, the Internet, an internet protocol network, MPLS network, a content distribution network, any network, or any combination thereof. Illustratively, servers 140, 145, and 150 are shown as being included within communications network 135. In certain embodiments, the communications network 135 may be part of a single autonomous system that is located in a particular geographic region, or be part of multiple autonomous systems that span several geographic regions.
Notably, the functionality of the system 100 may be supported and executed by using any combination of the servers 140, 145, 150, and 160. The servers 140, 145, and 150 may reside in communications network 135, however, in certain embodiments, the servers 140, 145, 150 may reside outside communications network 135. The servers 140, 145, and 150 may provide and serve as a server service that performs the various operations and functions provided by the system 100. In certain embodiments, the server 140 may include a memory 141 that includes instructions, and a processor 142 that executes the instructions from the memory 141 to perform various operations that are performed by the server 140. The processor 142 may be hardware, software, or a combination thereof. Similarly, the server 145 may include a memory 146 that includes instructions, and a processor 147 that executes the instructions from the memory 146 to perform the various operations that are performed by the server 145. Furthermore, the server 150 may include a memory 151 that includes instructions, and a processor 152 that executes the instructions from the memory 151 to perform the various operations that are performed by the server 150. In certain embodiments, the servers 140, 145, 150, and 160 may be network servers, routers, gateways, switches, media distribution hubs, signal transfer points, service control points, service switching points, firewalls, routers, edge devices, nodes, computers, mobile devices, or any other suitable computing device, or any combination thereof. In certain embodiments, the servers 140, 145, 150 may be communicatively linked to the communications network 135, any network, any device in the system 100, or any combination thereof.
The database 155 of the system 100 may be utilized to store and relay information that traverses the system 100, cache content that traverses the system 100, store data about each of the devices in the system 100 and perform any other typical functions of a database. In certain embodiments, the database 155 may be connected to or reside within the communications network 135, any other network, or a combination thereof. In certain embodiments, the database 155 may serve as a central repository for any information associated with any of the devices and information associated with the system 100. Furthermore, the database 155 may include a processor and memory or be connected to a processor and memory to perform the various operation associated with the database 155. In certain embodiments, the database 155 may be connected to the servers 140, 145, 150, 160, the first user device 102, the second user device 111, the additional user devices, the radiation device 800, the rotator device 200, any devices in the system 100, any process of the system 100, any program of the system 100, any other device, any network, or any combination thereof.
The database 155 may also store information and metadata obtained from the system 100, store metadata and other information associated with the first and second users 101, 110, store data generated by the radiation device 800, store data generated by the rotator device 200, store temperature readings obtained via sensors of the rotator device 200, storing any type of sensor reading from any type of sensor of the rotator device 200, store orientation and/or rotation information associated with the slots and/or vials/tubes held in the slots of the rotator device 200, store user profiles associated with the first and second users 101, 110, store device profiles associated with any device in the system 100, store communications traversing the system 100, store user preferences, store information associated with any device or signal in the system 100, store information relating to patterns of usage relating to the user devices 102, 111, store any information obtained from any of the networks in the system 100, store historical data associated with the first and second users 101, 110, store device characteristics, store information relating to any devices associated with the first and second users 101, 110, store information associated with the communications network 135, store any information generated and/or processed by the system 100, store any of the information disclosed for any of the operations and functions disclosed for the system 100 herewith, store any information traversing the system 100, or any combination thereof. Furthermore, the database 155 may be configured to process queries sent to it by any device in the system 100.
As shown in the diagrams and schematics illustrated in
In certain embodiments, the container 202 of the rotator device 200 may include one or more slots 205 within which a vial/tube 206 containing a sample may be placed. In certain embodiments, a slot 205 may have a semicircular shape (or any other desired shape) that allows a portion of a vial/tube 206 to reside within the semicircular portion of the slot 205 when the vial/tube 206 is dropped into the slot 205. In certain embodiments, the slot 205 may have any suitable shape, which may be tailored to receive a portion of a vial/tube 206. In certain embodiments, any number of protrusions may be present in each slot 205 so as to reduce rolling friction when a vial/tube 206 is positioned in the slot 205. In a preferred embodiment, each slot 205 may include two protrusions for reducing rolling friction, such as when the vial/tube 206 is rotated using the cup 204. In certain embodiments, the slots 205 may be bored into the container 202 such that the slots 205 have angles such that when the rotator device 200 is placed in (or within range of) the perpendicular irradiation plane 810 of the radiation device 800, the angles of the samples in the vials/tubes 206 in the slots 205 are between 0 and 180 degrees in the perpendicular irradiation plane 810. In certain embodiments and as shown in
In certain embodiments, the cup 204 of the rotator device 200 may be the component of the rotator device 200 that rotates the tubes/vials 206. The cup 204 itself may be dropped into the container 202 and may be attached to the container 202 and to the driveshaft 432 using the screw 402 and washer 404, as is shown in
Once the cup 204 is secured to the rotator device 200 and the vials/tubes 206 are positioned in the slots 205, the rotator device 200 may be positioned and secured onto the stand mount 210 of an adjustable-height stand 212. In certain embodiments, the rotator device 200 may be secured to the stand mount 210 using the screws 1204 or other screws described in the present disclosure. In certain embodiments, a cover plate 302 may reside between the stand mount 210 of the adjustable-height stand 212 and the base of the rotator device 200. In certain embodiments, the cover plate 302, the base of the rotator device 200, and the stand mount 210 may include one or more bored holes 1206 for receiving the screws 1204, and the cover plate 302 may be placed over stand mount 210 such that the holes 304 of the cover plate 302 and the stand mount 210 are aligned with each other. The screws 1204 may then be inserted into the holes 1206 of the stand mount 210 and the cover plate 302 when the holes 1206, 304, 470 of the stand mount 210, the cover plate 302, and the base of the rotator device 200 are aligned. Once the screws 1204 are inserted, the screws 1204 may be tightened as necessary to secure the cover plate 302, the stand mount 210, and the base of the rotator device 200 together. Once the stand mount 210 is secured to the adjustable-height stand 212 and the rotator device 200, the knob 804 may be turned in a clockwise direction so as to cause the adjustable-height stand 212 to expand and raise the rotator device 200 upwards. For example, when the rotator device 200 is secured to the adjustable-height stand 212 and vials/tubes 206 with samples are present in the slots 205, the knob 804 may be turned to cause the adjustable-height stand 212 to raise the rotator device 200 closer towards a radiation field (e.g. field including photons 820) emitted by a radiation device 800 (e.g. an x-ray tube or other radiation device). In certain embodiments, the knob 804 may be turned in a counter-clockwise direction to cause the adjustable-height stand 212 to contract and thereby lower the rotator device 200 downwards. Once the desired height is reached for the adjustable-height stand 212, a user can simply stop turning the knob 804.
In certain embodiments, the rotator device 200 may include any number of motors, such as motor 438, for powering the rotator device 200. In certain embodiments, the motor 438 of the rotator device 200, when activated, may be configured to generate torque, which may be transmitted to the driveshaft 432 that is connected to the motor 438 using the driveshaft collar 436. The torque transmitted to the driveshaft 138 may be transmitted from the driveshaft 138 to the cup 204 so as to cause the cup 204 to rotate. The rotating cup 204 may then cause any vials/tubes 206 present in the slots to rotate based on friction facilitated by the O-rings 426, 428, which may be in contact with the vials/tubes 206. In certain embodiments, the motor 438 may be protected and shielded by utilizing a motor shield 414 and the motor shield 414 may be protected by utilizing a motor shield shield 434. In the event the motor 438 and/or driveshaft 432 need to be replaced, a user may detach the stand mount 210 from the base of the rotator device 200 and may remove each of these components as necessary, as is shown in
In still further embodiments, the rotator device 200 may include any number of processors, memories, storage compartments, storage devices, transceivers, any other component, or a combination thereof. For example, the rotator device 200 may include a memory that stores instructions for operating the various functional features of the rotator device 200. The processor, which may be a combination of software, hardware, or both, may be configured to execute the instructions from the memory to perform various operations of the rotator device 200. For example, the processor may execute the instructions to cause the motor 438 to activate and provide torque to the driveshaft 432 so that the drive shaft 432 can rotate the cup 204 of the rotator device 200. The rotator device 200 may include any number of transceivers, which may be configured to enable the rotator device 200 to communicate with the first user device 102, the second user device 111, the servers 140, 150, 160, any other device of the system 100, or a combination thereof. In certain embodiments, the first user device 102, the second user device 111, and/or other devices of the system 100 may not only communicate with the rotator device 200, but also transmit signals to control the rotator device 200. For example, the first user 101 may control the rotator device 200 by inputting commands via a software application executing on the first user device 102 that communicatively links with the rotator device 200.
In addition to the embodiments described above and elsewhere in the present disclosure, the system 100 may also include further embodiments. For example,
As is shown in
Operatively, the system 100 may operate and/or execute the functionality as described in the methods of the present disclosure and in the following use case scenarios. According to an exemplary case scenario, the first user 101 may desire to irradiate a plurality of samples. In order to do so, the first user 101 may insert the samples into a plurality of vials/tubes 206. The first user 101 may then position the vials/tubes 206 containing the samples into the angled slots 205 (e.g. slots angled between 0 and 180 degrees relative to the perpendicular irradiation plane 810 of a radiation device 800) of the rotator device 200. The first user 101 may then position and secure the cup 204 including the O-rings 426, 428 to the container 202 of the rotating device 200 and to the driveshaft 432. The first user 101 may then activate the rotator device 200, which may cause the motor 438 to generate torque, which may be transmitted to the driveshaft 432. The torque transmitted to the driveshaft 432 may then be transmitted to the attached cup 204, which may cause the cup 204 to rotate. The rotating cup 204 may cause the vials/tubes 206 positioned in the angled slots 205 to rotate about their center axes via the O-rings 426, 428 secured to the outer surface of the cup 204. The angled slots 205 and the rotating of the samples about the center axes may facilitate uniform radiation exposure to the samples contained in the vials/tubes present in the angled slots 205 when the rotating device 200 is positioned within range of a radiation field of a radiation device 800. As another use case scenario, the first user 101 may desire to irradiate samples using the dual tube holder 1400 instead. In such a scenario, the first user 101 may simply position vials/tubes 206 containing samples into each of the tube holders of the dual tube holder 1400 and position the dual tube holder 1400 into the container 202 of the rotating device 200 or into another container. The first user 101 may then position the samples contained in the dual tube holder 1400 within range of a radiation device 800 so as to irradiate the samples.
Notably, as shown in
Although
Notably, the system 100 may execute and/or conduct the functionality as described in the method(s) that follow. As shown in
At step 2104, the method 2100 may include positioning a cup into the container of the rotating device 200. In certain embodiments, the cup may contact the vial/tube when the cup is positioned in the container and the vial containing the sample is positioned in the slot. In certain embodiments, the cup may contact the vial/tube via an O-ring or other similar component affixed and/or attached to the cup itself. In certain embodiments, the positioning of the cup into the container may be performed and/or facilitated by the first user 101, the second user 110 and/or by utilizing the first user device 102, second user device 111, the server 140, the server 145, the server 150, the server 160, the communications network 135, any combination thereof, or by utilizing any other appropriate program, network, system, or device. At step 2106, the method 2100 may include positioning the rotator device 200 within range of a radiation field emitted by the radiation device 800. In certain embodiments, the positioning of the rotator device 200 may be performed and/or facilitated by the first user 101, the second user 110 and/or by utilizing the first user device 102, second user device 111, the server 140, the server 145, the server 150, the server 160, the communications network 135, any combination thereof, or by utilizing any other appropriate program, network, system, or device.
At step 2108, the method 2100 may include activating the rotator device 200. In certain embodiments, the activation of the rotator device 200 may be performed and/or facilitated by the first user 101, the second user 110 and/or by utilizing the first user device 102, second user device 111, the server 140, the server 145, the server 150, the server 160, the communications network 135, any combination thereof, or by utilizing any other appropriate program, network, system, or device. At step 2110, the method 2100 may include transmitting, such as via a driveshaft of the rotator device 200, torque to the cup of the rotator device 200. The torque transmitted to the cup may cause the cup to rotate, thereby causing the cup to rotate the vial/tube containing the sample about a center axis of the vial/tube and/or sample. The angle of the slot and the rotation of the sample about the center axis may facilitate and cause uniform radiation exposure to the sample in the vial/tube when the rotator device 200 is in range of the radiation field of the radiation device 800. In certain embodiments, the transmitting of the torque may be performed and/or facilitated by utilizing by utilizing components of the rotator device 200, the first user device 102, second user device 111, the server 140, the server 145, the server 150, the server 160, the communications network 135, any combination thereof, or by utilizing any other appropriate program, network, system, or device. At step 2112, the method 2100 may include removing the vial/tube from the slot of the rotator device 200 after the sample has been irradiated via the radiation field emitted by the radiation device 800 according to required specifications. In certain embodiments, the removing of the vial/tube may be performed and/or facilitated by the first user 101, the second user 110 and/or by utilizing the first user device 102, second user device 111, the server 140, the server 145, the server 150, the server 160, the communications network 135, any combination thereof, or by utilizing any other appropriate program, network, system, or device. Notably, the method 2100 may further incorporate any of the features and functionality described for the system 100, any other method disclosed herein, or as otherwise described herein.
The systems and methods disclosed herein may include additional functionality and features. In certain embodiments, a sample to be irradiated typically may be placed flat (i.e. 0 degrees) with respect to the radiation field emitted by a radiation device. For example, the sample may be placed at a location within the radiation field that is directly across from the radiation device and is parallel to the perpendicular irradiation plane 810. In such a scenario, the sample would only be irradiated on the side facing the emitter of the radiation device. In order to irradiate the other side of the sample, the sample may need to be flipped along its axis so that the other side may be irradiated. In a preferred embodiment, instead of having the sample being placed flat with respect to the radiation field, the sample may be angled towards the radiation field to improve uniformity of the irradiation. For example, the sample may be angled between 0 and 180 degrees with respect to the perpendicular irradiation plane 810 so as to maximize uniformity and dose. This embodiment enables the sample to be irradiated more effectively and uniformly than the embodiment where the sample is placed flat with respect to the radiation field.
The systems and methods disclosed herein may include further functionality and features. For example, the operative functions of the system 100 and method may be configured to execute on a special-purpose processor specifically configured to carry out the operations provided by the system 100 and method. Notably, the operative features and functionality provided by the system 100 and method may increase the efficiency of computing devices that are being utilized to facilitate the functionality provided by the system 100 and the various methods discloses herein. For example, by training the system 100 over time based on data and/or other information provided and/or generated in the system 100, a reduced amount of computer operations need to be performed by the devices in the system 100 using the processors and memories of the system 100 than compared to traditional methodologies. In such a context, less processing power needs to be utilized because the processors and memories do not need to be dedicated for processing. As a result, there are substantial savings in the usage of computer resources by utilizing the software, techniques, and algorithms provided in the present disclosure. In certain embodiments, various operative functionality of the system 100 may be configured to execute on one or more graphics processors and/or application specific integrated processors.
Notably, in certain embodiments, various functions and features of the system 100 and methods may operate without any human intervention and may be conducted entirely by computing devices. In certain embodiments, for example, numerous computing devices may interact with devices of the system 100 to provide the functionality supported by the system 100. Additionally, in certain embodiments, the computing devices of the system 100 may operate continuously and without human intervention to reduce the possibility of errors being introduced into the system 100. In certain embodiments, the system 100 and methods may also provide effective computing resource management by utilizing the features and functions described in the present disclosure. For example, in certain embodiments, devices in the system 100 may transmit signals indicating that only a specific quantity of computer processor resources (e.g. processor clock cycles, processor speed, etc.) may be devoted to regulating the temperature of the rotator device 200, operating the radiation device 800, and/or performing any other operation conducted by the system 100, or any combination thereof. For example, the signal may indicate a number of processor cycles of a processor may be utilized to facilitate transmission of torque to the cup of the rotator device 200, and/or specify a selected amount of processing power that may be dedicated to generating or any of the operations performed by the system 100. In certain embodiments, a signal indicating the specific amount of computer processor resources or computer memory resources to be utilized for performing an operation of the system 100 may be transmitted from the first and/or second user devices 102, 111 to the various components of the system 100.
In certain embodiments, any device in the system 100 may transmit a signal to a memory device to cause the memory device to only dedicate a selected amount of memory resources to the various operations of the system 100. In certain embodiments, the system 100 and methods may also include transmitting signals to processors and memories to only perform the operative functions of the system 100 and methods at time periods when usage of processing resources and/or memory resources in the system 100 is at a selected value. In certain embodiments, the system 100 and methods may include transmitting signals to the memory devices utilized in the system 100, which indicate which specific sections of the memory should be utilized to store any of the data utilized or generated by the system 100. Notably, the signals transmitted to the processors and memories may be utilized to optimize the usage of computing resources while executing the operations conducted by the system 100. As a result, such functionality provides substantial operational efficiencies and improvements over existing technologies.
Referring now also to
In some embodiments, the machine may operate as a standalone device. In some embodiments, the machine may be connected (e.g., using communications network 135, another network, or a combination thereof) to and assist with operations performed by other machines and systems, such as, but not limited to, the first user device 102, the second user device 111, the rotator device 200, the server 140, the server 145, the server 150, the database 155, the server 160, the radiation device 800, any other system, program, and/or device, or any combination thereof. The machine may be connected with any component in the system 100. In a networked deployment, the machine may operate in the capacity of a server or a client user machine in a server-client user network environment, or as a peer machine in a peer-to-peer (or distributed) network environment. The machine may comprise a server computer, a client user computer, a personal computer (PC), a tablet PC, a laptop computer, a desktop computer, a control system, a network router, switch or bridge, or any machine capable of executing a set of instructions (sequential or otherwise) that specify actions to be taken by that machine. Further, while a single machine is illustrated, the term “machine” shall also be taken to include any collection of machines that individually or jointly execute a set (or multiple sets) of instructions to perform any one or more of the methodologies discussed herein.
The computer system 2200 may include a processor 2202 (e.g., a central processing unit (CPU), a graphics processing unit (GPU, or both), a main memory 2204 and a static memory 2206, which communicate with each other via a bus 2208. The computer system 2200 may further include a video display unit 2210, which may be, but is not limited to, a liquid crystal display (LCD), a flat panel, a solid state display, or a cathode ray tube (CRT). The computer system 2200 may include an input device 2212, such as, but not limited to, a keyboard, a cursor control device 2214, such as, but not limited to, a mouse, a disk drive unit 2216, a signal generation device 2218, such as, but not limited to, a speaker or remote control, and a network interface device 2220.
The disk drive unit 2216 may include a machine-readable medium 2222 on which is stored one or more sets of instructions 2224, such as, but not limited to, software embodying any one or more of the methodologies or functions described herein, including those methods illustrated above. The instructions 2224 may also reside, completely or at least partially, within the main memory 2204, the static memory 2206, or within the processor 2202, or a combination thereof, during execution thereof by the computer system 2200. The main memory 2204 and the processor 2202 also may constitute machine-readable media.
Dedicated hardware implementations including, but not limited to, application specific integrated circuits, programmable logic arrays and other hardware devices can likewise be constructed to implement the methods described herein. Applications that may include the apparatus and systems of various embodiments broadly include a variety of electronic and computer systems. Some embodiments implement functions in two or more specific interconnected hardware modules or devices with related control and data signals communicated between and through the modules, or as portions of an application-specific integrated circuit. Thus, the example system is applicable to software, firmware, and hardware implementations.
In accordance with various embodiments of the present disclosure, the methods described herein are intended for operation as software programs running on a computer processor. Furthermore, software implementations can include, but not limited to, distributed processing or component/object distributed processing, parallel processing, or virtual machine processing can also be constructed to implement the methods described herein.
The present disclosure contemplates a machine-readable medium 2222 containing instructions 2224 so that a device connected to the communications network 135, another network, or a combination thereof, can send or receive voice, video or data, and communicate over the communications network 135, another network, or a combination thereof, using the instructions. The instructions 2224 may further be transmitted or received over the communications network 135, another network, or a combination thereof, via the network interface device 2220.
While the machine-readable medium 2222 is shown in an example embodiment to be a single medium, the term “machine-readable medium” should be taken to include a single medium or multiple media (e.g., a centralized or distributed database, and/or associated caches and servers) that store the one or more sets of instructions. The term “machine-readable medium” shall also be taken to include any medium that is capable of storing, encoding or carrying a set of instructions for execution by the machine and that causes the machine to perform any one or more of the methodologies of the present disclosure.
The terms “machine-readable medium,” “machine-readable device,” or “computer-readable device” shall accordingly be taken to include, but not be limited to: memory devices, solid-state memories such as a memory card or other package that houses one or more read-only (non-volatile) memories, random access memories, or other re-writable (volatile) memories; magneto-optical or optical medium such as a disk or tape; or other self-contained information archive or set of archives is considered a distribution medium equivalent to a tangible storage medium. The “machine-readable medium,” “machine-readable device,” or “computer-readable device” may be non-transitory, and, in certain embodiments, may not include a wave or signal per se. Accordingly, the disclosure is considered to include any one or more of a machine-readable medium or a distribution medium, as listed herein and including art-recognized equivalents and successor media, in which the software implementations herein are stored.
The illustrations of arrangements described herein are intended to provide a general understanding of the structure of various embodiments, and they are not intended to serve as a complete description of all the elements and features of apparatus and systems that might make use of the structures described herein. Other arrangements may be utilized and derived therefrom, such that structural and logical substitutions and changes may be made without departing from the scope of this disclosure. Figures are also merely representational and may not be drawn to scale. Certain proportions thereof may be exaggerated, while others may be minimized. Accordingly, the specification and drawings are to be regarded in an illustrative rather than a restrictive sense.
Thus, although specific arrangements have been illustrated and described herein, it should be appreciated that any arrangement calculated to achieve the same purpose may be substituted for the specific arrangement shown. This disclosure is intended to cover any and all adaptations or variations of various embodiments and arrangements of the invention. Combinations of the above arrangements, and other arrangements not specifically described herein, will be apparent to those of skill in the art upon reviewing the above description. Therefore, it is intended that the disclosure not be limited to the particular arrangement(s) disclosed as the best mode contemplated for carrying out this invention, but that the invention will include all embodiments and arrangements falling within the scope of the appended claims.
The foregoing is provided for purposes of illustrating, explaining, and describing embodiments of this invention. Modifications and adaptations to these embodiments will be apparent to those skilled in the art and may be made without departing from the scope or spirit of this invention. Upon reviewing the aforementioned embodiments, it would be evident to an artisan with ordinary skill in the art that said embodiments can be modified, reduced, or enhanced without departing from the scope and spirit of the claims described below.
This application claims priority to and the benefit of U.S. Provisional Patent Application Ser. No. 62/879,272, filed on Jul. 26, 2019, the entire contents of which are incorporated by reference herein. Additionally, the entire disclosure of U.S. patent application Ser. No. 09/709,896, filed on Nov. 13, 2000, now U.S. Pat. No. 6,389,099, is incorporated by reference in its entirety.
| Number | Date | Country | |
|---|---|---|---|
| 62879272 | Jul 2019 | US |
