Claims
- 1. A process for the purification of (S)-4-{[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl]-methyl}-2-oxazolidinone which process comprises the steps of
- a) dissolving crude (S)-4-{[3-[2-(dimethylamino)ethyl]-1H-indole-5-yl]-methyl}-2-oxazolidinone in a refluxing mixture of ethanol in ethyl acetate and filtering the hot solution;
- b) slowly cooling the filtered solution to a temperature of about 5.degree. C.
- c) centrifuging the product from step b), washing with ethyl acetate then drying; and
- d) treating with acetone to remove solvated ethyl acetate.
Priority Claims (1)
Number |
Date |
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9516145 |
Aug 1995 |
GBX |
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Parent Case Info
This is a division of application Ser. No. 09/011,045, filed May 13, 1998, hereby incorporated by reference now U.S. Pat. No. 6,084,103.
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EPX |
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WOX |
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WOX |
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Non-Patent Literature Citations (1)
Entry |
International Search Report for PCT/GB/01885, Sep. 1996. |
Divisions (1)
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Number |
Date |
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Parent |
011045 |
May 1998 |
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