This application claims the priority benefit of Taiwan application serial no. 100144170, filed on Dec. 1, 2011. The entirety of the above-mentioned patent application is hereby incorporated by reference herein and made a part of this specification.
The disclosure relates to an optical interference apparatus.
In recent years, as optical coherence tomography adopts infrared light that is not easily absorbed by biological tissues, optical coherence tomography can be effectively applied to detection of biological tissues, and has become an indispensable tool in the biomedical field, for example, for examination of retinopathy in ophthalmology. A conventional optical coherence tomography system is an interferometer having a low coherence light source. A tomographic image of an object to be measured at different penetration depths is obtained by an interference signal caused by the difference between optical distances of an optical path where the object to be measured is located and a reference path in the interferometer.
However, in the prior art, when the object to be measured deviates from an optimal imaging position, the transverse resolution of the tomographic image is limited by optical properties of an objective lens used in the optical coherence tomography system. In other words, in the case that the numerical aperture of the objective lens is fixed, when the object to be measured deviates from the optimal imaging position, the transverse resolution of the tomographic image significantly decreases, seriously affecting the quality of the tomographic image of the object to be measured.
An optical interference apparatus capable of detecting an object is introduced herein. The optical interference apparatus includes a light source capable of emitting a light beam, an optical coupler disposed in a path of the light beam, a reflector, a first lens set and a light sensing unit. The optical coupler is capable of dividing the light beam into a measuring sub-light beam and a reference sub-light beam. The reflector is disposed in a path of the reference sub-light beam to reflect the reference sub-light beam. The first lens set includes a first lens disposed in a path of the measuring sub-light beam. The measuring sub-light beam is transmitted to the object after passing through the first lens set. The object reflects or scatters a part of the measuring sub-light beam back to the first lens set. The first lens has a spherical aberration and is capable of extending a depth of field of the first lens set. The light sensing unit is disposed in the path of the reference sub-light beam reflected from the reflector and in the path of the measuring sub-light beam transmitted back from the object and passing through the first lens set, to detect an interference signal formed by the reference sub-light beam and the measuring sub-light beam.
Several exemplary embodiments accompanied with figures are described in detail below to further describe the disclosure in details.
The accompanying drawings are included to provide further understanding, and are incorporated in and constitute a part of this specification. The drawings illustrate exemplary embodiments and, together with the description, serve to explain the principles of the disclosure.
An embodiment provides optical interference apparatus.
The light source 110 of this embodiment is capable of emitting a light beam L. In this embodiment, the light beam L may be a low coherence beam. In other words, the light source of this embodiment has such a luminescence spectrum that the coherence length of the light beam L is finite. In particular, in this embodiment, the width of the luminescence spectrum of the light beam L emitted by the light source may range from ten nanometers to several hundred nanometers. Moreover, the light beam L of this embodiment may be a Gaussian beam. That is, the transverse electric field intensity distribution of the light beam L may be close to a Gaussian function. The light beam L of this embodiment has a central wavelength of λ, where λ may range from 700 nanometers to 1400 nanometers. In other words, in this embodiment, the main intensity of the light beam L may be distributed in the near infrared band, so as to increase the ability of the light beam L to penetrate the object 10 (for example, biological tissue).
The optical coupler 120 of this embodiment is disposed in a path of the light beam L, and is capable of dividing the light beam L into a reference sub-light beam LR and a measuring sub-light beam LM. In other words, the light beam L emitted by the light source 110 may be transmitted to the optical coupler 120 through an optical fiber F. After the optical coupler 120 divides the light beam L into the reference sub-light beam LR and the measuring sub-light beam LM, the optical coupler 120 may transmit the reference sub-light beam LR and the measuring sub-light beam LM by using two optical fibers F1 and F2 respectively.
The first lens set 130 of this embodiment is capable of receiving the measuring sub-light beam LM from the optical coupler 120. The first lens set 130 includes a first collimating lens 132, a first lens 134 and a first objective lens 136. The first collimating lens 132, the first lens 134 and the first objective lens 136 are disposed in a path of the measuring sub-light beam LM. The measuring sub-light beam LM may be transmitted to the object 10 after passing through the first collimating lens 132, the first lens 134 and the first objective lens 136 in sequence. The object 10 is capable of reflecting or scattering at least a part of the measuring sub-light beam LM back to the first lens set 130. In this embodiment, the measuring sub-light beam LM from the object 10 and passing through the first lens set 130 may be transmitted to the optical coupler 120 through the optical fiber F2.
In addition, it should be noted that, in
The optical interference apparatus 100 of this embodiment may further include a second lens set 140. The second lens set 140 includes a second collimating lens 142 and a second objective lens 146 disposed in a path of the reference sub-light beam LR. The reference sub-light beam LR passes through the second collimating lens 142 and the second objective lens 146 in sequence.
In this embodiment, the reference sub-light beam LR may be transmitted to the reflector 150 after passing through the second lens set 140. The reflector 150 is capable of reflecting the reference sub-light beam LR back to the second lens set 140, so that the reference sub-light beam LR is transmitted back to the optical coupler 120.
In this embodiment, the reference sub-light beam LR reflected by the reflector 150 may be transmitted back to the optical coupler 120 through the optical fiber F1. The light sensing unit 160 of this embodiment is disposed in the path of the reference sub-light beam LR from the reflector 150 and in the path of the measuring sub-light beam LM transmitted back from the object 10 and passing through the first lens 134, to detect an interference signal formed by the reference sub-light beam LR and the measuring sub-light beam LM. In other words, in this embodiment, the optical coupler 120 may combine the reference sub-light beam LR from the reflector 150 and the measuring sub-light beam LM transmitted back from the object 10 and passing through the first lens set 130, and transmit the reference sub-light beam LR and the measuring sub-light beam LM to the light sensing unit 160 through an optical fiber F′.
A user can obtain a tomographic image of the object 10 through the interference signal formed by the reference sub-light beam LR and the measuring sub-light beam LM. For example, the optical interference apparatus 100 of this embodiment may be of a time domain type. The reflector 150 of this embodiment is capable of moving along the path of the reference sub-light beam LR. The light sensing unit 150 of this embodiment may be a photo-diode, a charge coupled device (CCD) or a complementary metal oxide semiconductor (CMOS) sensor. When an optical distance by which the measuring sub-light beam LM is reflected by an object at a particular penetration depth in the object 10 back to the light sensing unit 160 is equal to an optical distance by which the reference sub-light beam LR is reflected by the reflector 150 back to the light sensing unit 160, the light sensing unit 160 can detect an interference signal with maximum contrast. Therefore, the optical interference apparatus 100 of this embodiment can realize tomography by movement of the reflector 150. However, the disclosure is not limited thereto, and in other embodiments, the optical interference apparatus 100 may also be of a frequency domain type. In such embodiments, the light sensing unit 160 may be a spectrometer. A tomographic image of the object 10 may also be obtained by recording interference signals of difference wavelengths and in combination with a signal processing method such as Fourier transform.
It should be noted that, the first lens 134 of this embodiment has a spherical aberration to extend a depth of field of the first lens set 130. In other words, the first lens 134 is capable of increasing the depth of field of the first lens set 130. In this way, if the object 10 deviates from an optimal imaging position, the divergence of the measuring sub-light beam LM reflected by the object 10 does not easily increase with increasing deviation, thereby improving the transverse resolution of the tomographic image of the object 10.
Furthermore, in this embodiment, orders of spherical aberrations of the first lens 134 may be designed according to the condition that the incident light beam L is a Gaussian beam and a cut-off ratio of the width of the Gaussian beam to the system aperture, so as to optimize the performance of the optical interference apparatus 100. Specifically, in this embodiment, the spherical aberration of the first lens 134 includes at least one of all orders of spherical aberrations. In this embodiment, the spherical aberration of the first lens 134 may include a third-order spherical aberration and a fifth-order spherical aberration. An value of the third-order spherical aberration may fall within a range from 0.025λ to 5.000λ or from −5.000λ, to −0.025λ. An value of the fifth-order spherical aberration may fall within a range from 0.001λ to 5.000λ or from −5.000λ, to −0.001λ. Here, λ is the central wavelength of the light beam L.
Based on the above, in the optical interference apparatus according an embodiment of the disclosure, the depth of field of the first lens set can be increased by the spherical aberration, thereby improving the transverse resolution of the tomographic image of the object.
In the optical interference apparatus according to another embodiment of the disclosure, the second lens set also includes a spherical aberration similar to the first lens set. In other words, the measuring sub-light beam and the reference sub-light beam may respectively pass through the first lens set and the second lens set having similar optical effects. Therefore, the measuring sub-light beam and the reference sub-light beam transmitted back to the light sensing unit have similar light intensities, so that the interference signal received by the light sensing unit has good contrast (that is, large signal-to-noise ratio).
In the optical interference apparatus according to still another embodiment of the disclosure, the optical interference apparatus may further include a scanning reflector. The scanning reflector enables the measuring sub-light beam to scan every position of the object.
In the optical interference apparatus according to yet another embodiment of the disclosure, the first lens set may further include a cone-shaped lens. Under the action of the spherical aberration and the cone-shaped lens, the depth of field of the first lens set can be further increased, thereby further improving the performance of the optical interference apparatus.
It will be apparent to those skilled in the art that various modifications and variations can be made to the structure of the disclosed embodiments without departing from the scope or spirit of the disclosure. In view of the foregoing, it is intended that the disclosure cover modifications and variations of this disclosure provided they fall within the scope of the following claims and their equivalents.
Number | Date | Country | Kind |
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100144170 | Dec 2011 | TW | national |