1. Field of the Invention
The present invention relates to an optical measurement apparatus that measures optical properties of a scatterer and a probe for the measurement.
2. Description of the Related Art
In recent years, an optical measurement apparatus has been proposed, which uses a low-coherence enhanced backscattering (LEBS) technique for detecting characteristics of a scatterer by irradiating incoherent light having a short spatial coherence length onto the scatterer from a distal end of a probe and measuring scattered light (for example, see International Patent Publication Pamphlet No. WO 2007/133684). Such an optical measurement apparatus is able to perform optical measurement of a biological tissue, which is a scatterer, in combination with an endoscope for observing internal organs such as digestive organs. When this LEBS technique is used, it is required to detect each of at least two scattered light of different scattering angles.
Conventionally, a configuration for obtaining scattered light having a desired angle with a light detection fiber by providing an optical element such as a lens or a beam splitter at a distal end of a probe (for example, see U.S. Patent Application Publication No. 2008/0037024) or a configuration for obtaining scattered light having a desired angle by separating an illumination fiber from a light detection fiber by a predetermined distance (for example, see Biomedical Optics 2010 BtuD90) has been proposed.
An optical measurement apparatus according to an aspect of the present invention measures a property of a scatterer, and includes: a light source that supplies illumination light having at least one spectral component; an illumination fiber that propagates, to a distal end thereof, light supplied from a proximal end thereof by the light source and illuminates light onto the scatterer from the distal end; first and second light detection fibers, each of the first and second light detection fibers outputting, from a proximal end thereof, returned light from the scatterer, the returned light entering from a distal end thereof, the first and second light detection fibers having distal end positions different from each other in a longitudinal direction; a detection unit that detects light output from the proximal end of the first light detection fiber and the proximal end of the second light detection fiber; and a measurement unit that measures a property of the scatterer based on a result of the detection by the detection unit.
An optical measurement apparatus according to another aspect of the present invention measures a property of a scatterer, and includes: a light source that supplies illumination light having at least one spectral component; an illumination fiber that propagates light supplied from a proximal end thereof by the light source to a distal end thereof and illuminates light onto the scatterer from the distal end; a light detection fiber that is movable in a longitudinal direction and outputs, from a proximal end thereof, returned light from the scatterer, the returned light entering from a distal end thereof; a detection unit that detects light output from the proximal end of the light detection fiber; a measurement unit that measures a property of the scatterer based on a result of the detection by the detection unit; and a mover that relatively moves the light detection fiber in the longitudinal direction relative to the illumination fiber.
A probe for measurement, according to still another aspect of the present invention, which is detachably connected to an optical measurement apparatus that measures a property of a scatterer, includes: an illumination fiber that propagates, to a distal end thereof, light supplied from a proximal end thereof by a light source and illuminates light onto the scatterer from the distal end; and first and second light detection fibers, each of the first and second light detection fibers outputting, from a proximal end thereof, returned light from the scatterer, the returned light entering from a distal end thereof, the first and second light detection fibers having distal end positions different from each other in a longitudinal direction.
A probe for measurement according to yet another aspect of the present invention, which is detachably connected to an optical measurement apparatus that measures a property of a scatterer, includes: an illumination fiber that propagates light supplied from a proximal end thereof to a distal end thereof and illuminates light onto the scatterer from the distal end; and a light detection fiber that is movable in a longitudinal direction and outputs, from a proximal end thereof, returned light from the scatterer, the returned light entering from a distal end thereof.
The above and other objects, features, advantages and technical and industrial significance of this invention will be better understood by reading the following detailed description of presently preferred embodiments of the invention, when considered in connection with the accompanying drawings.
Hereinafter, preferred embodiments of an optical measurement apparatus and a probe according to the present invention will be described in detail with reference to the drawings. The invention is not limited by the embodiments. In the description of drawings, like reference numerals denote like elements. Further, it is to be noted that the drawings are schematic, and relations between thicknesses and widths of each element, and ratios among elements are different from those of the actual. Among the drawings also, a same portion having relations or ratios of dimensions different from one another is included.
The main unit 2 includes a power supply 21, a light source unit 22, a connector 23, a detection unit 24, an input unit 25, an output unit 26, and a control unit 27.
The power supply 21 supplies power to each element of the main unit 2.
The light source unit 22 generates light to be illuminated onto the object to be measured. The light source unit 22 includes an incoherent light source such as a white light-emitting diode (LED) or a xenon lamp, and one or more lenses. The light source unit 22 supplies to the probe 3, via the connector 23, incoherent light that has at least one spectral component and that is be illuminated onto the object to be measured.
The connector 23 detachably connects the proximal end of the probe 3 to the main unit 2. The connector 23 supplies, to the probe 3, the light emitted from the light source unit 22, and outputs the scattered light output from the probe 3 to the detection unit 24. The connector 23 outputs, to the control unit 27, information related to whether or not the probe 3 is connected.
The detection unit 24 detects detected light, which is the light output from the probe and is the scattered light from the object to be measured. The detection unit 24 is implemented using an optical detector, a spectrometer, a spectrometer, and the like. The detection unit 24 detects, via the connector 23, the scattered light output from the probe 3, and measures a spectral component, an intensity, and the like of the detected scattered light. The detection unit 24 outputs a result of the measurement to the control unit 27.
The input unit 25 is implemented using a push-type switch or the like, receives instruction information for instructing activation of the main unit 2 and various other types of instruction information, and inputs them into the control unit 27 by manipulation of a switch or the like.
The output unit 26 outputs information related to various processes in the optical measurement apparatus 1. The output unit 26 is implemented using a display, a speaker, a motor, or the like and outputs information related to various processes in the optical measurement apparatus 1 by outputting image information, audio information, or vibration.
The control unit 27 controls processing operations of each element of the main unit 2. The control unit 27 includes a central processing unit (CPU) and a semiconductor memory such as a random access memory (RAM). The control unit 27 controls operations of the main unit 2 by transferring and the like, to respective elements of the main unit 2, instruction information or data. The control unit 27 includes an analysis unit 27a that analyzes characteristics of the object to be measured based on a result of detection by the detection unit 24. That is, the analysis unit 27a functions as a measurement unit.
The probe 3 is implemented using a multiple number of optical fibers. The probe 3 includes a proximal end portion 31 detachably connected to the connector 23 of the main unit 2, a flexible portion 32 having flexibility, and a distal end portion 33 from which the light supplied from the light source unit 22 is emitted and into which the scattered light from the object to be measured enters.
The optical measurement apparatus 1 performs optical measurement in combination with an endoscope that observes internal organs such as digestive organs.
Next, the probe 3 illustrated in
As illustrated in
The illumination fiber 35 propagates the light supplied from the proximal end by the light source unit 22 to the distal end and illuminates light Li from the distal end to an object 39. Each of the first and second light detection fibers 36 and 37 outputs scattered light from the proximal end, which is returned light from the object 39, the returned light entering from the distal end. The detection unit 24 detects the light output from the proximal ends of the first and second light detection fibers 36 and 37.
As illustrated in
Further, positions of distal ends of the first and second light detection fibers 36 and 37 in a longitudinal direction are different from each other. In an example illustrated in
Here, when the LEBS technique is used, as illustrated by a curve Ps indicating scattering angle dependence of scattered light intensity of
In the first embodiment, the first light detection fiber 36 contacts the illumination fiber 35, and light scattered and reflected at an angle as close to that of the light illuminated from the illumination fiber 35 as possible enters the first light detection fiber 36. Thus, scattered light Ls having a scattering angle θ1 corresponding to the peak value As of the interference component of the scattered light enters the distal end of the first light detection fiber 36.
In addition, since the distal end of the second light detection fiber 37 protrudes towards the object 39 in a longitudinal direction more than the distal end of the first light detection fiber 36, scattered light Lb having a scattering angle θ2 corresponding to a base value Ab, which has a scattering angle greater than the scattering angle θ1, enters the distal end of the second light detection fiber 37. In this manner, the scattering angle θ of the scattered light entering each light detection fiber is determinable by a distance between the distal end of the light detection fiber and the object 39.
Therefore, conventionally, to obtain scattered light having a desired angle, it is necessary to separate the illumination fiber 135 from the second light detection fiber 137 by a certain distance and thus there is a limit to decrease in a diameter of the probe 103.
In contrast, according to the first embodiment, each fiber is arranged such that the distal end of the second light detection fiber 37 protrudes towards the object 39 in a longitudinal direction more than the distal end of the first light detection fiber 36. As a result, it is possible to obtain scattered light Lb having a scattering angle θ2 even if the illumination fiber 35 is adjacent to the second light detection fiber 37. Therefore, according to the first embodiment, since the second light detection fiber 37 that obtains scattered light Lb having a scattering angle θ2 is able to be arranged adjacently to the illumination fiber 35, it is possible to decrease the diameter of the probe 3.
In addition, in the first embodiment, although description has been made for an example in which the position of the distal end of the illumination fiber 35 is aligned with the position of the distal end of the first light detection fiber 36, limitation is not made thereto. Scattered light having a scattering angle even closer to 0° may be obtained by arranging the first light detection fiber 36 such that a position of the distal end of the light detection fiber 36 is located more towards the proximal end of the probe 3 in a longitudinal direction than a position of the distal end of the illumination fiber 35.
Next, a first modification of the first embodiment will be described.
As illustrated in
Here, a spatial coherence length of illumination light is (λ·S)/(π·D), when λ denotes a wavelength of light, S denotes a distance from a light emission surface of an illumination fiber to an object, and D denotes a core diameter of the fiber. The distance between a distal end surface of an illumination fiber 35 and an object 38 is preferably constant in order to perform light illumination with a stable spatial coherence length.
The cap 40 allows light to be illuminated in a state where the distance between the illumination fiber 35 and the object is fixed and the spatial coherence length is infallibly made constant. Further, the cap 40 also allows a distance Ss between the first light detection fiber 36 and an object 39 and a distance Sb between the second light detection fiber 37 and the object 39 to be fixed, and light having a predetermined scattering angle to be stably detected. Furthermore, since the surface of the object 39 is planarized by a bottom surface of the cap 40, measurement is possible without being influenced by concavity and convexity of a surface of the object 39.
In addition, as illustrated in
Like the probe 3B of
As illustrated in
When the illumination fiber 35 and the first and second light detection fibers 36 and 37 are arranged like this, it is possible to further decrease a diameter of the probe 3C.
As illustrated in
As described, by using a group of fibers including a multiple number of fibers, it is possible to obtain more scattered light of the same angle.
Next, a second embodiment will be described. Scattered light having different scattering angles are obtained by moving a position of a distal end of a light detection fiber.
As illustrated in
The main unit 202 includes a connector 223 that outputs scattered light output from a probe 203 to a detection unit 24 and a control unit 227 having a function similar to that of the control unit 27. Similarly to the probe 3, the probe 203 includes a proximal end portion 231 detachably connected to the connector 223 of the main unit 202, a flexible portion 232 having flexibility, and a distal end portion 233 from which light supplied from a light source unit 22 is emitted and into which scattered light from an object to be measured enters. The probe 203 is movable in a longitudinal direction with the illumination fiber 35 and has a light detection fiber 236 (see
As illustrated in
As indicated by an arrow Y20 of
Next, as indicated by an arrow Y22 of
In this manner, according to the second embodiment, the mover 350 is able to move the light detection fiber 236 such that the distal end of the light detection fiber 236 is located at a first position and a second position different from the first position in a longitudinal direction of the light detection fiber 236. The detection unit 24 detects each of returned light entering from the distal end of the light detection fiber 236 at the first position and returned light entering from the distal end of the light detection fiber 236 at the second position. The analysis unit 27a measures properties of the object based on a result of the detection by the detection unit 24 corresponding to the first and second positions.
Therefore, according to the second embodiment, since scattered light of a plurality of angles are obtainable with one light detection fiber 236 and one optical detector by moving the light detection fiber 236 along the longitudinal direction, it is possible to reduce the number of light detection fibers than in the first embodiment. Therefore, according to the second embodiment, it is possible to further decrease a diameter of the probe 203.
In addition, according to the second embodiment, it is possible to obtain scattered light of any scattering angle within an angle range Sn from a scattering angle θ1 to a scattering angle θn that corresponds to a position adjacent to the object 39 as illustrated in
In addition, according to the second embodiment, like a probe 203A illustrated in
Next, the mover 350 will be described.
The whole detection unit 24 to which the light detection fiber 236 is connected may be moved in order to move the light detection fiber 236. As illustrated in
According to an embodiment of the present invention, because the positions, in the longitudinal direction, of the distal ends of the first and second light detection fibers differ from each other, even if the illumination fiber is adjacent to the first and second light detection fibers, it is possible to obtain scattered light having a desired scattering angle and to decrease the diameter of the probe.
According to another embodiment of the present invention, because the light detection fiber is movable in a longitudinal direction, by moving in the longitudinal direction with respect to the illumination fiber, even if the illumination fiber is adjacent to the light detection fiber, it is possible to obtain scattered light having a desired scattering angle and to decrease the diameter of the probe.
Additional advantages and modifications will readily occur to those skilled in the art. Therefore, the invention in its broader aspects is not limited to the specific details and representative embodiments shown and described herein. Accordingly, various modifications may be made without departing from the spirit or scope of the general inventive concept as defined by the appended claims and their equivalents.
This application is a continuation of PCT international application Ser. No. PCT/JP2011/074567 filed on Oct. 25, 2011, which designates the United States and claims the benefit of priority from U.S. provisional patent application No. 61/408,176 filed on Oct. 29, 2010, and the entire contents of the PCT international application and the U.S. provisional patent application are incorporated herein by reference.
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Number | Date | Country | |
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20130235384 A1 | Sep 2013 | US |
Number | Date | Country | |
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61408176 | Oct 2010 | US |
Number | Date | Country | |
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Parent | PCT/JP2011/074567 | Oct 2011 | US |
Child | 13870396 | US |