Claims
- 1. Optically active (6R, 7S) compounds represented by the formula: ##STR11## wherein R.sub.1 represents hydrogen or a carboxyl-protecting group selected from the group consisting of: straight-chain or branched alkyl having 1 to 5 carbons, straight-chain or branched alkoxymethyl having 1 to 5 carbons, straight-chain or branched halogenated alkyl having 1 to 5 carbons, lower alkylsulfonylethyl, arylmethyl having 7 to 12 carbons, substituted arylmethyl having 7 to 20 carbons wherein the substituent is methoxy or nitro and the number of substituents on the phenyl ring is 1 to 5, and a protective group of carboxylic acid represented by the formula: ##STR12## wherein R.sub.2 is straight-chain or branched lower alkyl having 1 to 5 carbons, straight-chain or branched lower alkoxy having 1 to 5 carbons, or phenyl; and R.sub.3 is hydrogen or straight-chain or branched lower alkyl having 1 to 5 carbons;
- Hal represents a halogen atom; and pharmaceutically acceptable salts thereof.
- 2. The compound according to claim 1, wherein R.sub.1 is a hydrogen.
- 3. The compound according to claim 2, wherein Hal is a chlorine atom, that is (6R, 7S) 7-amino-3-chloro-1-azabicyclo[4,2,0]oct-2en-8-on-2-carboxylic acid.
Priority Claims (1)
Number |
Date |
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54-146488 |
Nov 1979 |
JPX |
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Parent Case Info
This application is a continuation of application Ser. No. 825,696, filed Feb. 3, 1986, now abandoned, which is a continuation of application Ser. No. 732,893, filed May 9, 1985, now abandoned, which is a continuation of application Ser. No. 643,101, filed Aug. 22, 1984, now abandoned, which is a continuation of application Ser. No. 518,315, filed July 29, 1983, now abandoned, which is a continuation of application Ser. No. 291,129, filed Aug. 7, 1981, now abandoned, which is a division of application Ser. No. 206,639 filed Nov. 13, 1980, now U.S. Pat. No. 4,302,541.
US Referenced Citations (1)
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Name |
Date |
Kind |
4123528 |
Cama |
Oct 1978 |
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Hirata et al., Chem. Abs., 93, 239247t. |
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Divisions (1)
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Parent |
206639 |
Nov 1980 |
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Continuations (5)
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825696 |
Feb 1986 |
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Parent |
732893 |
May 1985 |
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Parent |
643101 |
Aug 1984 |
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Parent |
518315 |
Jul 1983 |
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Parent |
291129 |
Aug 1981 |
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