Claims
- 1. The optically active compounds of the formula ##STR25## wherein R.sub.2 represents a hydrogen or a group represented by the formula ##STR26## wherein R.sub.3 is a straight or branched lower alkyl group having 1 to 6 carbon atoms, a straight or branched lower alkoxy group having 1 to 6 carbon atoms or a phenyl group and R.sub.4 is a hydrogen or a straight or branched lower alkyl group having 1 to 6 carbon atoms; and A.sub.2 represents a straight or branched lower alkyl group having 1 to 6 carbon atoms or a straight or branched lower alkyl froup having 1to 6 carbon atoms which is substituted with one or two carboxyl groups, and pharmaceutically acceptable salts thereof.
- 2. A compound according to claim 1 wherein R.sub.2 is hydrogen.
- 3. A compound according to claim 1 wherein the OH group is in the form of alpha-bonding.
- 4. A compound according to claim 1 wherein R.sub.2 is hydrogen, A.sub.2 is a methyl group and the OH group is in the form of alpha-bonding, that is, (4S, 6R, 7S-7-[2-(2-amino-4-thiazolyl)-2-syn-methoxyimino-acetamido]-4-hydroxy-1-azabicyclo[4,2,0]-oct-2-en-8-on-2-carboxylic acid.
- 5. A compound according to claim 1 wherein R.sub.2 is a hydrogen, A.sub.2 is a 2-carboxypropan-2-yl and the OH group is in the form of alpha-bonding, that is, (4S, 6R, 7S)-7-[2-(2-amino-4-thiazolyl)-2-syn-(2-carboxyprop-2-oxyimino)acetamido]-4-hydroxy-1-azabicyclo[4,2,0]oct-2-en-8-on-2-carboxylic acid.
Priority Claims (3)
Number |
Date |
Country |
Kind |
54-136987 |
Oct 1979 |
JPX |
|
55-22035 |
Feb 1980 |
JPX |
|
55-55619 |
Apr 1980 |
JPX |
|
Parent Case Info
This application is a continuation of application Ser. No. 629,755 filed July 13, 1984, now abandoned, which is a continuation of application Ser. No. 390,024 filed June 18, 1982, now abandoned, which is, in turn, a continuation of application Ser. No. 200,556, filed Oct. 24, 1980, now abandoned.
US Referenced Citations (2)
Number |
Name |
Date |
Kind |
4218793 |
Durkheimer |
Jul 1981 |
|
4291164 |
Hirata et al. |
Sep 1981 |
|
Foreign Referenced Citations (2)
Number |
Date |
Country |
2740280 |
Mar 1978 |
DEX |
1538240 |
Jan 1979 |
GBX |
Continuations (3)
|
Number |
Date |
Country |
Parent |
629755 |
Jul 1984 |
|
Parent |
390024 |
Jun 1982 |
|
Parent |
200556 |
Oct 1980 |
|