Claims
- 1. An optically active hydroxybenzylamine derivative represented by the formula (I) ##STR19## wherein R.sup.1 denotes a hydrogen atom, lower alkyl group or lower alkoxy group; R.sup.2 denotes a lower alkyl group; * signifies an asymmetric carbon atom; and the hydroxyl group is located on the phenyl at the ortho-or meta-position relative to the substituent having the asymmetric carbon atom.
- 2. The derivative according to claim 1, wherein the hydroxyl group is located on the phenyl at the ortho-position relative to the substituent having the asymmetric carbon atom.
- 3. The derivative according to claim 3, wherein R.sup.1 is a lower alkoxy group.
- 4. The derivative according to claim 3, wherein the lower alkoxy group is substituted at the meta-position relative to the substituent having the asymmetric carbon atom.
- 5. The derivative according to claim 2, wherein R.sup.1 is a hydrogen atom or lower alkyl group.
- 6. The derivative according to claim 1, wherein the hydroxyl group is located on the phenyl at the meta-position relative to the substituent having the asymmetric carbon atom.
- 7. A process for producing an optically active hydroxylbenzylamine derivative represented by the formula (I) ##STR20## wherein R.sup.1 denotes a hydrogen atom, lower alkyl group or lower alkoxy group; R.sup.2 denotes a lower alkyl group; * signifies an asymmetric carbon atom; and the hydroxyl group is located on the phenyl at the ortho-or meta-position relative to the substituent having the asymmetric carbon atom, which comprises subjecting an optically active amine represented by the formula (IX) ##STR21## wherein R.sup.1 and R.sup.2 are as defined above; * signifies an asymmetric carbon atom; and the benzyloxy group is located on the phenyl at the ortho- or meta-position relative to the substituent having the asymmetric carbon atom, or its acid salts thereof to hydrogenolysis in the presence of a hydrogenation catalyst.
- 8. The process according to claim 7, wherein the hydroxyl group is located on the phenyl at the ortho-position relative to the substituent having the asymmetric carbon atom.
- 9. The process according to claim 8, wherein R.sup.1 is a lower alkoxy group.
- 10. The process according to claim 9, wherein the lower alkoxy group is located on the phenyl at the meta-position relative to the substituent having the asymmetric carbon atom.
- 11. The process according to claim 8, wherein R.sup.1 is a hydrogen atom or lower alkyl group.
- 12. The process according to claim 7, wherein the hydroxyl group is located on the phenyl at the meta-position relative to the substituent having the asymmetric carbon atom.
Priority Claims (1)
Number |
Date |
Country |
Kind |
62-256017 |
Oct 1987 |
JPX |
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Parent Case Info
This is a division of application Ser. No. 07/652,607, filed Feb. 8, 1991, now U.S. Pat. No. 5,120,853, which in turn is a division of application Ser. No. 07/251,789, filed Oct. 3, 1988, now U.S. Pat. No. 5,011,989.
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Entry |
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Divisions (2)
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Number |
Date |
Country |
Parent |
652607 |
Feb 1991 |
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Parent |
251789 |
Oct 1988 |
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