Patent Application
20230346358
The subject matter of the present disclosure relates generally to the field of oral appliances. More particularly, the present disclosure relates to devices for restoring the appliance subsequent to use and for tracking patient wellness by detection of properties from the oral appliance.
An objective of orthodontics is to move a patient's teeth to positions where function and/or aesthetics are optimized. Traditionally, appliances such as braces are applied to a patient's teeth by a treating practitioner and the set of braces exerts continual force on the teeth and gradually urges them toward their intended positions. Over time and with a series of clinical visits and reactive adjustments to the braces by the practitioner, the appliances move the teeth toward a desired destination. More recently, alternatives to conventional orthodontic treatment with traditional affixed appliances (e.g., braces) have become available. For example, systems including a series of molded plastic aligners have become commercially available from Align Technology, Inc., San Jose, Calif., under the trade name Invisalign® System. The Invisalign® System is described in numerous patents and patent applications assigned to Align Technology, Inc. including, for example in U.S. Pat. Nos. 6,450,807, and 5,975,893.
Like traditional braces, aligners are required to be worn near constant wear protocol (20-22 hours a day), with breaks allowed for eating and cleaning teeth. Patient compliance with the wear protocol is greatly determinative of a successful orthodontic result. However, for various reasons, a certain number of patients do not comply with the wear protocol. This can result in a non-successful orthodontic result that requires a new series of aligners to be made or abandonment of the procedure. Compliance tracking devices exist, however, they rely on simple sensors that are generally not capable of determining whether a current aligner is present or rather some other object, such as a prior aligner.
Additionally, thermally molded polymer aligners are subject to forces during wear and can lose their preset shape over time. The preset shape controls the target positioning of the user's teeth. If the preset shape of the aligner is changed, so shall the target positioning of the user's teeth. This is undesirable.
Accordingly, there is a need for improved systems that address the above challenges.
In embodiments of the invention, an oral appliance rejuvenation system is operable to restore an oral appliance by heating the appliance according to an annealing temperature-time profile sufficient to remove stresses in the appliance arising from wear.
In some embodiments of the invention, the oral appliance rejuvenation system is further operable to perform one or more of the following additional functions: cleaning or sanitizing, active ingredient loading, sensing to monitor compliance and optionally, to detect analyte information, and sample collection.
The system may take a wide variety of configurations. Some embodiments of the present disclosure relate to an aligner body or case having a compartment for housing electronics and a compartment for housing aligners.
The electronics are programmed and operable to perform a wide variety of different modes examples of which include: restoring or annealing, cleaning or sanitizing, active ingredient loading, sensing to monitor compliance and optionally, to detect analyte information, and sample collection.
In some embodiments, the electronics can detect the presence of the aligners and communicate with an external device, such as a smart phone, to provide appliance compliance information to a caregiver.
Some embodiments relate to a method for prescribing use of an oral appliance. In the method, time information generated by an oral appliance holder is received. The information can be related to detecting presence or non-presence of an oral appliance within the holder. The oral appliance can be one of a series of pre-designed oral appliances prescribed for oral treatment of a patient. It can be determined from the time information that the appliance was not present within the oral appliance holder for a required amount of time. The prescribed use of the series oral appliances can be altered based on the appliance not being present within the oral appliance holder for the required amount of time.
In some embodiments, accessing can include accessing a remote server to download or view the information.
In some embodiments, altering the prescribed use of the series oral appliances can include changing an appliance currently used by the patient.
In some embodiments, altering the prescribed use of the series oral appliances can include changing reevaluating the patient for a new series of oral appliances.
In some embodiments, altering the prescribed use of the series oral appliances can include prescribing changing a currently prescribed oral appliance back to a prior oral appliance.
Some embodiments relate to a device for storing an oral appliance. The device can include an openable container. The openable container can have an appliance holding portion, a processor, a memory module coupled to the processor, a communication module, and a sensing module coupled to the appliance holding portion and the processor. The sensing module can be configured to generate to generate analyte information, the analyte information can be related to presence or non-presence of volatilized compounds emanating from an oral appliance at the appliance holding portion. The processor can be configured to receive the analyte information from the sensing module, generate and store use information within the memory module. The use information can include at least the analyte information. The communication module can transmit the use information to an external device.
In embodiments, a system for rejuvenating an oral appliance includes a cavity for holding the appliance. A lid is arranged with the body to cover and uncover the cavity. The system further includes a rejuvenation module and a processor programmed or operable to control the rejuvenation module to heat the appliance in the cavity according to a predetermined temperature time profile which removes stress in the appliance arising from wear. In a preferred embodiment, the rejuvenation module includes a resistive-based heating element operable to warm the appliance by thermal conduction. However, in other embodiments, the heater is an infrared heater.
In embodiments, the system further includes a sanitation module operable to clean, and optionally sterilize the appliance in the container. In a preferred embodiment, the sanitation module heats and optionally agitates the appliance in a liquid bath. Agitation may be performed by an ultrasonic element operable to send ultrasonic waves through the liquid and towards the appliance, serving to dislodge and remove dirt and bacteria that can build up on the aligner during wear. In some embodiments, the appliance is sterilized by directing ultrasound or radiation at the appliance during the sanitation mode. In embodiments, sterilization is performed on the appliance after the liquid is evacuated from the container, or the appliance is otherwise dry.
In embodiments, a system includes a fluid transport network for transporting liquids, agents, samples to and from the different cavities or tanks according to the user selected mode. The fluid transport network includes a plurality of tubes and valves controlled by the processor. Optionally the fluid transport network is arranged to drive the fluid by gravity, a pump, or pressure/pneumatic action.
In embodiments, the system comprises a saliva collecting mode in which a saliva sample is collected from the appliance. A removable saliva collector and a fluid transport network are operable with the processor to, prior to the cleaning mode, transport a saliva sample rinsed from the appliance to the collector. In embodiments, the saliva is automatically rinsed from the appliance by delivering clean water over the appliance.
In embodiments, the system further includes a compliance monitoring module for detecting or computing the amount of time the user wears the appliance. In a preferred embodiment, a sensor detects for the presence of the appliance in the container and computes the wear time based on the time the appliance is contained in the container. Information regarding the rejuvenation, cleaning, and wear time, amongst other things, can be recorded and stored in memory and optionally communicated to an external device via the communication module.
Some embodiments relate to a method in which analyte information can be received from a sensing module of an oral appliance holder, the analyte information can be related to presence or non-presence of an oral appliance at the appliance holding portion of the oral appliance holder. Use information can be generated and stored at a memory module of the oral appliance holder. The use information can include at least the analyte information. A communication module of the oral appliance holder can be connected to an external device. The use information can be transmitted from the oral appliance holder to an external device.
Some embodiments relate to a non-transitory processor-readable medium for an oral appliance holder, the non-transitory processor-readable medium can include processor-readable instructions configured to cause one or more processors of the oral appliance holder to perform a method in which analyte information can be received from a sensing module of the oral appliance holder. The analyte information can be related to presence or non-presence of an oral appliance at the appliance holding portion of the oral appliance holder. Use information can be generated and stored at a memory module of the oral appliance holder. The use information can include at least the analyte information. A communication module of the oral appliance holder can be connected to an external device. The use information can be transmitted from the oral appliance holder to an external device.
In some embodiments, the volatilized compounds comprise one or more of alkanes, alkenes, alkynes, dienes, alicyclic hydrocarbons, arenes, alcohols, ethers, ketones, aldehydes, carbonyls, carbanions, polynuclear aromatics, biomolecules, sugars, isoprenes isoprenoids, volatile organic compounds (VOC), volatile organic analytes (VOA), indoles, skatoles, diamines, pyridines, picolines, an off-gas of a microorganism and fatty acid, pentane, hydrogen sulfide, methyl mercaptan, ammonia, acetone, butane, and sulfides.
In some embodiments, the openable container can include a top lid at least partially removably connected to a bottom housing.
In some embodiments, at least one of the processors, memory module, communication module, and sensing module can be housed within the bottom housing.
In some embodiments, the communication module can be configured to wirelessly communicate with the external device.
In some embodiments, the external device is a smartphone or tablet.
In some embodiments, the sensing module can include at least one sensor.
In some embodiments, the at least one sensor can include at least one of an infra-red, piezo-electric, strain-gauge, hall-effect, capacitive, ultrasonic, microwave, radio, magnetic, humidity, or optical sensor.
In some embodiments, the external device can include a network access device.
In some embodiments, the network access device can be configured to transmit the use information to a remote server.
In some embodiments, a sanitizing module can be configured to sanitize the oral appliance at the appliance holding portion.
Some embodiments relate to a server that can have at least one processor. The at least one processor can be configured to perform a method in which a record can be received from a first external device. The record can include at least one, a single event, or multiple events that indicate the presence or non-presence of an oral appliance within an oral appliance holder. The events can include analyte information of volatilized compounds emanating from the oral appliance. The record can be correlated with a patient's master record. The patient's master record can be updated to include the record. Remote access to the patient's master record by a second external device can be enabled.
Some embodiments relate to a method in which a record can be received from a first external device. The record can include a single event or multiple events that indicate the presence or non-presence of an oral appliance within an oral appliance holder. The record can be correlated with a patient's master record. The patient's master record can be updated to include the record. Remote access to the patient's master record by a second external device can be enabled.
Some embodiments relate to a non-transitory processor-readable medium for a server.
The non-transitory processor-readable medium can include processor-readable instructions configured to cause one or more processors of the server to perform a method in which a record can be received from a first external device. The record can include a single event or multiple events that indicate the presence or non-presence of an oral appliance within an oral appliance holder. The record can be correlated with a patient's master record. The patient's master record can be updated to include the record. Remote access to the patient's master record by a second external device can be enabled.
In some embodiments, the first external device can include a network access device communicatively couplable with the oral appliance holder.
In some embodiments, the analyte information can be correlated to at least one health attribute, bodily function, and/or wellness indicator.
In some embodiments, updating the patient's master record can include correlating analyte information with pre-existing information of the patient's master record to develop a statistically weighted model for the at least one health attribute, bodily function, and/or wellness indicator.
In some embodiments, the statistically based model can be a sub-profile of a plurality of sub-profiles that make up a health profile of the patient.
In some embodiments, the first external device can be the oral appliance holder.
In some embodiments, the record can include a unique identifier that is associated with the patient's master record from a database.
In some embodiments, correlating the record with a patient's master record can include performing an operation to match the unique identifier with the master record and retrieving the patient's master record.
In some embodiments, the record can include values associated with an alert.
In some embodiments, an operation triggered by detection of the alert can be performed.
In some embodiments, the operation can include sending an electronic message associated with the alert to a third-party.
In some embodiments, the electronic message can be sent to the first external device or the second external device.
The description, objects and advantages of embodiments of the present invention will become apparent from the detailed description to follow, together with the accompanying drawings.
Before the present invention is described in greater detail, it is to be understood that this invention is not limited to particular embodiments described, as such can, of course, vary. It is also to be understood that the terminology used herein is for the purpose of describing particular embodiments only, and is not intended to be limiting, since the scope of the present invention will be limited only by the appended claims. Where a range of values is provided, it is understood that each intervening value, to the tenth of the unit of the lower limit unless the context clearly dictates otherwise, between the upper and lower limit of that range and any other stated or intervening value in that stated range, is encompassed within the invention. The upper and lower limits of these smaller ranges can independently be included in the smaller ranges and are also encompassed within the invention, subject to any specifically excluded limit in the stated range. Where the stated range includes one or both of the limits, ranges excluding either or both of those included limits are also included in the invention. Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. Although any methods and materials similar or equivalent to those described herein can also be used in the practice or testing of the present invention, representative illustrative methods and materials are now described. It is noted that, as used herein and in the appended claims, the singular forms “a”, “an”, and “the” include plural referents unless the context clearly dictates otherwise. It is further noted that the claims can be drafted to exclude any optional element. As such, this statement is intended to serve as antecedent basis for use of such exclusive terminology as “solely,” “only” and the like in connection with the recitation of claim elements, or use of a “negative” limitation. As will be apparent to those of skill in the art upon reading this disclosure, each of the individual embodiments described and illustrated herein has discrete components and features which can be readily separated from or combined with the features of any of the other several embodiments without departing from the scope or spirit of the present invention. Any recited method can be carried out in the order of events recited or in any other order that is logically possible.
All existing subject matter mentioned herein (e.g., publications, patents, patent applications and hardware) is incorporated by reference herein in its entirety except insofar as the subject matter may conflict with that of the present invention (in which case what is present herein shall prevail).
International Publication No. WO2020/223380, filed Apr. 29, 2020, and entitled “ORAL APPLIANCE HOLDER” is incorporated herein by referenced in its entirety for all purposes.
Sensor module 120 can detect one or more types of condition associated with appliance holder 100. Sensor module 120 can detect a condition associated with the presence or non-presence of an oral appliance held within the appliance holder, as two examples. Sensor module 120 can continuously or intermittently provide processing system 110 with an indication of the condition. Sensor module 120 can detect a presence or motion within the interior environment of appliance holder 200. Sensor module 120 can include one or more sensors, such as an infra-red, piezo-electric, strain-gauge, hall-effect, capacitive, ultrasonic, microwave, radio (e.g., RFID reader), magnetic, humidity (e.g., capacitive, resistive, or thermal), or optical sensor. In some embodiments, sensor module 120 can include one or more passive infrared (PIR) sensors and/or ultrasonic sensors that receive infrared radiation (or reflected ultrasonic sound) from the ambient environment of the appliance holder. For instance, insertion of an appliance or opening a lid of appliance holder 200 emits infrared radiation which can be detected by sensor module 120. In other embodiments, sensor module 120 can use some other form of sensor than a PIR sensor. In some embodiments, sensor module 120 can include one or more humidity sensors that detect moisture produced by a damp appliance within the ambient environment of the appliance holder. Sensor module 120 can provide an indication to processing system 110 of when motion is present in the ambient environment of appliance holder 200. More generally, sensor module 120 can be a form of sensor that can detect presence of an appliance even if motionless. In some embodiments, sensor module 120 outputs raw data that is analyzed by processing system 110 to determine if motion is present or a user is otherwise present. In some embodiments, motion can be analyzed to determine if it likely corresponds to presence of an appliance or is incidental.
In some embodiments, sensor module 120 can be configured to detect volatilized compounds, i.e., breath odors, emanating from appliances stored within appliance holder 100.
Volatilized compounds can be captured and detected over an extended period of time. Unlike simpler sensors, such as infrared sensors, odor sensor compliance can be better tracked because detection of odor can be correlated to drying bacteria of a recently worn aligner. An older aligner left within the case would cause a false positive with regards to compliance using a simple sensor, however this would be avoided using an odor sensor because the older aligner would provide little to no odor, or only odor below a certain threshold. In addition, an odor sensor can be used to track wellness data, which provides additional patient motivation to comply with an aligner protocol or wearing a retainer or similar oral device. In some embodiments, the oral device is constructed in the same manner as an aligner or retainer, e.g., as a clear aligner, but does not adjust or maintain tooth position, but rather is only used by the patient for tracking wellness.
In some embodiments, appliance holder 100 can include a duct and/or fan system to cause volatilized compounds to be deposited onto a sensor. In some embodiments, sensor module 120 can include an electronic nose sensor array, a differential mobility spectrometer, an electrochemical gas sensor, a surface acoustic wave sensor, quartz microbalance sensor, conductive composite, chemiresistor, metal oxide gas sensor and conducting polymer sensor, dye-impregnated polymer film on fiber optic detector, polymer-coated micromirror, an electrochemical gas detector, a chemically sensitive field-effect transistor, carbon black-polymer composite, micro-electro-mechanical system device, and micro-opto-electro-mechanical system device. In some embodiments, sensor module 120 can be configured as an electronic nose and includes of an array of polymer films embedded with conductive or resistive material. When exposed to substance such as a fluid, e.g., a gas, as applied to the present system, the polymer films may swell or contract thereby leading to a change in the DC electrical resistance of the film. The DC resistance across each of the films in the array may be sampled at approximately uniformly-spaced times resulting in a unique signature.
The presence of one or more volatilized compounds can be used to determine the presence of an oral appliance within appliance holder 100. Such volatilized compounds can include analytes deposited on the oral appliances via saliva and directly or indirectly caused by bacteria, viruses, chemical imbalances, dehydration. Such analytes can include organic compounds that can be found in volatilized compounds, which, for example, can include alkanes, alkenes, alkynes, dienes, alicyclic hydrocarbons, arenes, alcohols, ethers, ketones, aldehydes, carbonyls, carbanions, polynuclear aromatics, biomolecules, sugars, isoprenes isoprenoids, volatile organic compounds (VOC), volatile organic analytes (VOA), indoles, skatoles, diamines, pyridines, picolines, an off-gas of a microorganism and fatty acid, pentane, hydrogen sulfide, methyl mercaptan, ammonia, acetone, butane, sulfides, methoxybenzene (anisole), 2-butanone, methyl 2-ethylhexanoate, methyl 2-ethylhexanoate, methyl propionate, 2-pentanone, 3-pentanone, 2,4-dimethyl-1-heptene, methyl isobutyl ketone, 6-methyl-5-hepten-2-one, dimethylsulfoxide, dimethylsulfide, methyl 2-methylpropionate, l-ethoxy-2-methylpropane, 1-ethoxy-butane, t-butyl ethyl ether, methyl 2-methyl butanoate, isobutanol, dimethyl sulfide, 2,3-butanedione, 3-hydroxy-2-butanone, butyl acetate, and benzeneacetaldehyde, methanethiol, 2-heptanone, 2-nonanone, and/or 2-undecanone.
Detection and quantification of the odor can also be used to correlate to one or more health conditions of the patient. For example, health conditions such as bad breath, dehydration, diabetes, liver disease, respiratory tract infections, chronic bronchitis, acid reflux, heart disease, gum disease, periodontitis, cancer, infections, pneumonia, ovulation, bacteria presence, and xerostomia. Examples of sensors used to detect airborne analytes that can be attributable to one or more health conditions are described at publications U.S. Pat. No. 6,244,096B1, US20150105683A1, US20040147038A1, U.S. Pat. No. 9,733,226B1, US20060160134A1, US20090247890A1, U.S. Pat. No. 7,977,103B2, US20040236244A1, US20050208614A1, U.S. Pat. No. 6,709,635B1, U.S. Pat. No. 6,575,013B2, U.S. Pat. No. 7,531,137B2, US20090230300A1, US20090230300A1, US20100191474A1, U.S. Pat. No. 8,366,630B2, and U.S. Pat. No. 8,366,630B2, which are incorporated by reference herein.
Processing system 110 can be configured to analyze an amount of time the condition is detected by sensor module 120. Processing system 110 can create a record of the amount of time the condition is detected by sensor module 120. Communication module 130 can be configured to transfer the record to an external device, such as a mobile communication device, remote server, or general-purpose computer. Communication module 130 can be a wired and/or wireless transmission device.
Appliance holder 200 represents a more detailed embodiment that includes a greater number of optional components and modules. In appliance holder 200, various components can be present including: processing system 110, sensor module 120, indicator light 210, sanitizing module 220, line power source 215, battery-based power source 220, wireless communication module 225, wired communication module 230, and user input component 235.
Processing system 110 of appliance holder 200 can include multiple submodules. Such submodules can be implemented using hardware, firmware, and/or software that is executed by underlying hardware, such as one or more processors. Such modules can include: sensor engine 112, sanitization engine 114, records engine 116, and communications engine 118. For example, such modules can represent code that is executed by a high-level processor and/or a low-level processor of appliance holder 200. Sensor engine 112 can control one or more sensors, for example by activating, deactivating, or regulating power to such sensors. Sensor engine 112 can also receive indications of the condition detected in the appliance holding area of the appliance holder 200 indicating the presence or non-presence of an appliance. In some embodiments, Sensor engine 112 can perform quantitative measurement of one or analytes, such as volatilized compounds. Sensor engine 112 can create time-based records of the indications. Sensor engine 112 can send the records to records engine 116. Records engine 116 can control and include a non-transitory medium, such as flash memory, for storing records received from sensor engine and/or sanitization engine 114. Records engine 116 can be in communication with communication engine 118. Records engine 116 can output records stored in memory to the communication engine 118 based on a signal from communication engine 118.
Sanitizing module 205 can represent a sanitizing device for sanitizing an appliance held by appliance holder 200. Sanitizing module 205 can include an ultraviolet light source or ultrasonic wave inducing transducer. Sanitization engine 114 can control sanitizing module 205 to initiate a sanitization cycle according to a user input, according to a schedule, or by detecting an event, for example, whenever an appliance is placed within appliance holder 200 a sterilization cycle will be initiated. Sanitization engine 114 can output data to records engine 116 for the purpose of creating sanitization records by records engine 116. Sanitization engine 114 can output a signal to indicator light 210 to provide a visual indication to user that the sanitization process is underway or an error has occurred that prevents completion of the sanitization process.
Indicator light 210 can represent a light integrated into appliance holder 200 that outputs light to the external environment around appliance holder 200. Indicator light 210 can be controlled by processing system 110 to indicate to a use of functional status, appliance holder mode, or a wear reminder. Indicator light 210 can include one or more lighting elements, such as light emitting diodes (LEDs). Indicator light 210 can be capable of outputting various illumination modes that can include: multiple colors, multiple animation patterns, and/or such multiple animation patterns at varying speeds. The at least one color, animation pattern, and speed of animation output by indicator light 210 can be determined based on a determination performed by processing system 110. Therefore, based on conditions monitored by processing system 110, indicator light 210 can be illuminated or disabled. When indicator light 210 is illuminated, the one or more colors, animation pattern, and/or speed of the animation output by indicator light 210 can vary based on a determination performed by processing system 110.
Communication engine 118 controls intercommunication between modules of processing system 110. Communication engine 118 also controls wireless communication module 225 and/or wired communication module 230. Wireless communication module 225 and/or wired communication module 230 can allow communication engine 118 to communicate with an external network and/or device. For instance, wireless communication module 225 can communicate with a wireless network that uses the IEEE 802.11a/b/g network protocol standard for communication. Wireless communication module 225 can permit communication engine 118 to communicate with a remote server, which can be maintained by a manufacturer of appliance holder 200 or by a third-party.
The remote server can be configured to provide information to processing system 110 by way of communication engine 118. For example, if one or more modules of processing system 110 require updates, related data can be provided to processing system 110 via wireless communication module 225. Further, communication engine 118 can transmit status information to a remote server, for example information related to data collected by sensor module 120. Such an arrangement can permit an authorized person, such as a care provider, to view information about the use of the appliance holder.
Wireless communication module 225 can permit direct connection with a wireless computerized device, such as a tablet computer or smartphone. In some embodiments, communication is performed via a network connection through a router or other form of direct communication, such as Bluetooth®, Bluetooth LE®, or WiFi Direct®. Once connected, messages can be exchanged between processing system 110 (via wireless communication module 225) and a wireless computerized device, such as to permit an initial configuration of appliance holder 200 to be performed via the computerized wireless device or indirect communication with the remote server. Communication with external devices and/or networks can be intermittent. Hence, when connection with external devices and/or networks is realized, communication engine 118 can communicate to other modules, such as records engine 116, to transmit status and stored records.
User input component 235 can represent a component that receives input that can be passed to processing system 110. User input component 235 can take the form of a button or switch on appliance holder 200. By depressing the button or otherwise actuating user input component 235, a user can provide input via user input component 235 to processing system 110, for example, user input component 235 can be used by a user to initialize a sterilization process by sanitization module 205, reset indicator light 210, or initiate electronic communication with an external device (e.g., initiate wireless discovery mode). Different modes associated with inputs to input component 235 can be initiated according to the length of time input component 235 is activated.
Appliance holder 200 can include battery-based power source 220 and/or line power source 215. Line power source 215 can be used to power appliance holder 200 when such power is available. Line power source 215 can represent a port (e.g., USB port) and a removable wired connection (e.g., USB cable) and/or an inductive charging module that provides DC power from an external source (e.g., AC/DC wall plug, USB port). Line power source 215 can share a common connector (e.g., USB port) with wired communication module 230. In embodiments, line power comprises a standard AC power cord, and the holder or system can include an AC/DC power converter to provide the proper amount of current to the various modules (e.g., the sanitation module or rejuvenation module discussed herein) as well as other computer electronics.
Battery-based power source 220 can include one or more batteries which power the various components of appliance holder 200 when line power source 215 is not available. The batteries can be rechargeable and non-replaceable or be user replaceable. Line power source 215 can provide charging power to batteries of battery power source 220. In some embodiments of appliance holder 200, line power source 215 is not present and/or the appliance holder cannot be capable of connected with line power source 215. Line power source 215 and battery-based power source 220 are illustrated in
The data sent by appliance holder 310 can be raw data that requires additional processing to create user appliance wear records (e.g., the estimated amount of time the user is using the appliance). Such processing can be, for example, correlating data generated by appliance holder 310 (i.e., time-based data related to detecting presence or non-presence of an oral appliance) to create the wear record. Records server 340 can store such records in database 360. Records server 340 can be configured to provide alerts to care-providers when records correlate with patient non-compliance. Such an alert can be sent to care provider's network access device 370 in the form of an email or other specialized alert. Records server 340 can also be configured to provide wear reminders to patients when records correlate with patient non-compliance. Such a reminder can be sent to patient's network access device 330 in the form of an email, text, and/or or other specialized alert. Such a reminder can additionally or alternatively be sent to appliance holder 310, which can provide a visual alert (e.g., intermittently flashing indicator light 210).
A care provider using network access device 370 can access the records stored on database 360 by communicating with records server 340 through communications network 320.
The records can be assigned to a specific patient and formatted for use by a specific application of network access device 370, or alternatively accessible on records server 340 via a web-based application. Based on the records, a care provider can determine whether the user of the appliance associated with appliance holder 310 is wearing the appliance correctly. For example, the appliance can be one of a series of pre-designed oral appliances prescribed for oral treatment of a patient. The series of appliances are designed to incrementally move the teeth from an initial position to a final position to achieve an oral result (e.g., teeth straightening). This is achieved by relatively small movement changes caused by each appliance; hence, it is important for the patient to properly wear each appliance according to a prescribed protocol (e.g., 20 hours/day) to achieve the desired orthodontic result, which non-compliance by the user can negate.
Records that indicate that the appliance is outside of appliance holder 310 for a certain amount of time (e.g., 20-23 hours/day) can be indicative that the patient is complying with the prescribed protocol. This can be verified with in-person examination by the care provider, because such a record can also indicate that the patient is not using appliance holder 310 to store the appliance. If the records correlate with patient compliance, the care provider can adjust the examination follow-up schedule to reduce the number of follow-up examinations required.
Records that indicate that the appliance is outside of appliance holder 310 for a certain amount of time (e.g., 0-19 hours/day) can be indicative that the patient is not complying with the prescribed protocol. Based on interpolating these records, the care provider can contact the patient to investigate whether the patient is not being compliant or whether appliance holder 310 is malfunctioning and sending false records. If an examination indicates that the patient is compliant with the prescribed protocol, then the records do not correlate with non-compliance, which can indicate a fault in appliance holder 310. In such cases, a new appliance holder can be issued to the patient. If records correlate with non-compliance, the prescribed protocol can be adjusted, by for example, rescanning the patient's teeth for a new series of appliances or reverting sequencing back to a prior appliance.
In some embodiments, records server 340 can be configured to receive data regarding the presence/non-presence and/or quantity of one or more types of analytes found in volatilized compounds detected within appliance holder. Such data can be raw data sent by appliance holder 310 and/or processed data from appliance holder 310. In some embodiments, records server 340 can be configured to correlate the processed data with one or more health attributes and maintain a health profile of a patient by updating the health profile with the health attributes. In some embodiments, records server 340 can correlate the processed data with one or more genetic attributes and maintain a health profile of a patient by updating the health profile with the genetic attributes.
Data can be processed by records server 340 to determine the type, presence, relative concentration, ratio, and/or quantity of the one or more analytes, which can function as biomarkers. In some embodiments, a multiplex of analytes can be identified. In some embodiments, records server 340 can be configured to correlate the type, presence, relative concentration, ratio, and/or quantity of one or more analytes to known biomarkers for one or more of a pathology, condition, or health status to determine one or more health attributes.
Health attributes can include nutritional information, disease information, hormone information, genetic information, hydration information, PH level information, fluoride information, mineralization information, alcohol information, microbiome information, infectious disease information, cancer information, inflammation information, and/or virus information. Saliva borne biomarkers have been associated with a wide variety of diseases, viral infections, bacterial infections, parasites, physical impairment, inflammation, nutritional imbalances, hormonal imbalances, hormonal levels, menstrual cycles, adrenal disease, diabetes, asthma attacks, cancers, stress, fertility, pregnancy status, sex of a fetus, wellness of a fetus, ovulation status, fertility level, and other wellness issues.
In some embodiments, records server 340 can update the health profile of the patient and compare the most recent data to prior health profiles. In some embodiments, records server 340 can provide statistically weighted statuses and/or predictions of patient wellness based on the health profiles. In some embodiments, alerts for acute indications can be provided to the patient and/or a patient's caregiver so that the patient can seek immediate care. In some embodiments, a patient's health profile can be tracked to provide a life-time view of wellness, hence, the collected data can provide a better understanding of a patient's health and disease risks, and greater emphasis can be placed on disease prevention and maintaining optimal health for the long term. In some embodiments, lifestyle changes, hormonal, nutritional, dietary, behavioral, and/or therapeutic drug therapies can be recommended by records server 340 based on conditions predicted by the patient's health profile.
In some embodiments, records server 340 can be configured retrieve a patient health profile and update the profile based on the one or more correlated health attributes. In some embodiments, the health profile can be a statistically based model for one or more pathologies.
The health profile can be determined by one or more algorithms. The health profile can provide one or more of status, risk, likelihood, tendency, intensity, level, amount, for one or more of the health attributes. The patient health profile can include data regarding past diagnostic tests (e.g., blood/serum tests, salivary tests) records of health events, genetic information, genetic ancestry, psychological information, prescribed drug use, illicit drug use, alcohol use, smoking history, age, weight, race, environmental exposure history, and family health histories. In some embodiments, the patient health profile can be updated in parallel by other sources, for example, by wearable devices that record daily activity, heart rate, etc. In some embodiments, the patient health profile can be updated in parallel by other patient health profiles, which can be anonymized, that share similar genetic profiles, genetic ancestry, live and/or work in the same vicinity, share similar lifestyles, and/or are directly related to the patient. Some or all of these data points can be weighted and considered by system 100 when making conclusions and recommendations based on the detected biomarkers.
In some embodiments, a health profile can made up of several sub-profiles, which are derived from information based on the correlated health attributes. A sub-profile can be a statistically based model for a particular pathology. Each sub-profile can be determined by one or more algorithms. Each sub-profile can provide one or more of status, risk, likelihood, tendency, intensity, level, amount, for a health attribute. Such sub-profiles can include a nutritional profile, disease profile, hormone profile, genetic profile, hydration profile, PH profile, fluoride profile, mineralization profile, alcohol profile, microbiome profile, infectious disease profile, cancer profile, inflammation profile, and/or virus profile.
In some embodiments, records server 340 can be configured for performing predictive analytics to discover new biomarkers, i.e., in order to make statistical determinations on whether a particular analyte, which is not currently determined to be a biomarker, is actually a biomarker in whole or in part for a particular pathology. This can be performed by analyzing data stored in records server 340 of a statistically relevant number of patients with saliva that test positive or negative for the same analyte (e.g., concentration, amount) and have or do not have the same corresponding pathology. This analysis can be supplemented by comparison to additional data, (e.g., lifestyle, genetics, etc.). Records server 340 can have an AI learning function to perform such discoveries without being commanded to. In some embodiments, this function is performed by a separate bioinformatics engine. Examples of predictive analytics systems and methodology using large data sets are disclosed in U.S. Pat. No. 7,444,308 B2; U.S. Pat. No. 9,679,104 B2; and U.S. Pub. No. 2016/0026917 A1, which are incorporated by reference herein.
At operation 410, the processor creates a record of the event. A sensor of the appliance holder can generate raw data. The decision to process the raw data can be based on the raw data meeting or exceeding a value threshold, which indicates the raw data is useful for creating a record on a non-transitory medium. If the raw data does not meet or exceed the value threshold, no further processing is required, and no record of the event will be created. In some embodiments, the raw data regards the presence/non-presence and/or quantity of one or more types of analytes found in volatilized compounds detected within the appliance holder. The raw data can include a set of data sampled by the sensor according to a predetermined sampling rate, for example, 1 sample per 1-10 seconds or 1-60 minutes. The raw data can be further processed (e.g., to include one or more time-stamps) and/or unique identification information to create the record. The raw data can also be incorporated into an existing record (e.g., a daily record) that includes data from events that occurred prior to the event. At operation 415, the processor transmits the record of the event to an external device, such as a smart phone or remote server.
Transmission can occur when the processor is connected to the external device by way of a wireless or wired connection. After the record is transmitted, the record can be marked for deletion or overwriting by the processor.
The record can include certain values that are associated with an alert. For example, the values can be associated with compliance or non-compliance with a prescribed appliance wear protocol. In some embodiments, the processor can send a reminder alert to the appliance holder or other device associated with the patient (e.g., smartphone, smartwatch) to remind the patient to wear the appliance. In some embodiments, the processor can send a congratulatory message to the device associated with the patient (e.g., smartphone, smartwatch) to encourage continued compliance with the prescribed appliance wear protocol. In some embodiments, the processor can send an alert to the patient's assigned caregiver that indicates the patient may not be complying with the prescribed appliance wear protocol. In some embodiments, the processor can provide an alert to a health care provider regarding a health related event associated with the correlated health attributes.
In some embodiments, the record includes a patient health profile which can be updated based on the one or more correlated health attributes. In some embodiments, the health profile can be a statistically based model for one or more pathologies. The health profile can be determined by one or more algorithms, which can factor in health attributes collected over weeks, months, and/or years. The health profile can provide one or more of status, risk, likelihood, tendency, intensity, level, amount, for one or more of the health attributes. The patient health profile can include data regarding past diagnostic tests (e.g., blood/serum tests, salivary tests) records of health events, genetic information, genetic ancestry, psychological information, prescribed drug use, illicit drug use, alcohol use, smoking history, age, weight, race, environmental exposure history, and family health histories. In some embodiments, the patient health profile can be updated in parallel by other sources, for example, by wearable devices that record daily activity, heart rate, etc. In some embodiments, the patient health profile can be updated in parallel by other patient health profiles, which can be anonymized, that share similar genetic profiles, genetic ancestry, live and/or work in the same vicinity, share similar lifestyles, and/or are directly related to the patient. Some or all of these data points can be weighted and considered when making conclusions and recommendations based on the detected biomarkers.
In some embodiments, a health profile can made up of several sub-profiles, which are derived from information based on the correlated health attributes. A sub-profile can be a statistically based model for a particular pathology. Each sub-profile can be determined by one or more algorithms. Each sub-profile can provide one or more of status, risk, likelihood, tendency, intensity, level, amount, for a health attribute. Such sub-profiles can include a nutritional profile, disease profile, hormone profile, genetic profile, hydration profile, PH profile, fluoride profile, mineralization profile, alcohol profile, microbiome profile, infectious disease profile, cancer profile, inflammation profile, and/or virus profile.
In some embodiments, predictive analytics can be performed to discover new biomarkers, i.e., in order to make statistical determinations on whether a particular analyte, which is not currently determined to be a biomarker, is actually a biomarker in whole or in part for a particular pathology. This can be performed by analyzing data stored in records of a statistically relevant number of patients with saliva that test positive or negative for the same analyte (e.g., concentration, amount) and have or do not have the same corresponding pathology. This analysis can be supplemented by comparison to additional data, (e.g., lifestyle, genetics, etc.).
At operation 435, the processor enables viewing of all or a portion of the updated master record by the patient's caregiver. Viewing can be enabled by allowing the updated master record to be downloaded by the caregiver's network access device or viewed on a web-based application hosted by the server. In some embodiments, each time the master record is updated or according to a predetermined schedule, the process sends the master record to the caregiver's network access device. In some embodiments, all or portion of the master record can also be made available to the patient's network access device.
In some embodiments, only certain teeth received by an appliance will be repositioned by the appliance while other teeth can provide a base or anchor region for holding the appliance in place as it applies force against the tooth or teeth targeted for repositioning. In some cases, many or most, and even all, of the teeth will be repositioned at some point during treatment.
Teeth that are moved can also serve as a base or anchor for holding the appliance as it is worn by the patient. Typically, no wires or other means will be provided for holding an appliance in place over the teeth. In some cases, however, it may be desirable or necessary to provide individual anchors on teeth with corresponding receptacles or apertures in the appliance so that the appliance can apply a selected force on the tooth. Basic methods for determining an orthodontic treatment plan using a series of incremented appliances as well as instructions for molding oral appliances, are described in U.S. Pat. Nos. 6,450,807, and 5,975,893, which are incorporated by reference herein, but only to an extent that those patents do not contradict the newer teachings disclosed herein.
An appliance can be designed and/or provided as part of a set of a plurality of appliances. In such an embodiment, each appliance may be configured so a tooth-receiving cavity has a geometry corresponding to an intermediate or final tooth arrangement intended for the appliance. The patient's teeth can be progressively repositioned from an initial tooth arrangement to a target tooth arrangement by placing a series of incremental position adjustment appliances over the patient's teeth. A target tooth arrangement can be a planned final tooth arrangement selected for the patient's teeth at the end of all planned orthodontic treatment.
Alternatively, a target arrangement can be one of many intermediate arrangements for the patient's teeth during the course of orthodontic treatment. As such, it is understood that a target tooth arrangement can be any planned resulting arrangement for the patient's teeth that follows one or more incremental repositioning stages. Likewise, an initial tooth arrangement can be any initial arrangement for the patient's teeth that is followed by one or more incremental repositioning stages.
The oral appliances can be generated all at the same stage or in sets or batches, e.g., at the beginning of a stage of the treatment, and the patient wears each appliance until the pressure of each appliance on the teeth can no longer be felt or has resulted in the maximum amount of expressed tooth movement for that given stage. A plurality of different appliances (e.g., set) can be designed and even fabricated prior to the patient wearing any appliance of the plurality. After wearing an appliance for an appropriate period of time, the patient replaces the current appliance with the next appliance in the series until no more appliances remain. The oral appliances are generally not affixed to the teeth and the patient may place and replace the appliances at any time during the procedure (e.g., patient-removable appliances).
The final oral appliance or several appliances in the series may have a geometry or geometries selected to overcorrect the tooth arrangement, i.e., have a geometry which would (if fully achieved) move individual teeth beyond the tooth arrangement which has been selected as the “final.” Such over-correction may be desirable to offset potential relapse after the repositioning method has been terminated, i.e., to permit movement of individual teeth back toward their pre-corrected positions. Over-correction may also be beneficial to speed the rate of correction, i.e., by having an appliance with a geometry that is positioned beyond a desired intermediate or final position, the individual teeth will be shifted toward the position at a greater rate. In such cases, the use of an appliance can be terminated before the teeth reach the positions defined by the appliance.
Examples of orthodontic appliances are described in US Patent Publication No. 20210153979A1, entitled “ELASTIC ORTHODONTIC APPLIANCES, SYSTEMS, AND METHODS FOR USE.”
Appliance holder 600 includes top lid 605, which can be hinged to bottom housing 610. Top lid 605 and bottom housing 610 can be constructed from a metal or polymer material. Top lid 605 and/or bottom housing 610 are depicted as having a circular shape, but can also have different shapes, such as rectangular.
Top lid 605 and/or bottom housing 610 can house numerous components. For example, processing system 110, sensor module 120, indicator light 210, sanitizing module 220, line power source 215, battery-based power source 220, wireless communication module 225, wired communication module 230, and user input component 235 can be stored internally within top lid 605 and/or bottom housing 610. Top lid 605 and/or bottom housing 610 can include features for enabling access to such components, such as battery compartment lids, internal antennas, and communication/line power ports. Top lid 605 and/or bottom housing 610 have interior surfaces that form a cavity for storage of one or more oral appliances (AP), as shown at
Surfaces of the cavity can include sensor ports that enable detection of oral appliances.
Two tanks 730, 740 are shown in a cavity in the body 710. As described further herein, first tank 730 is for rejuvenating. First tank 730 may be made of a thermally transmitting material such as stainless steel. A heating element 732 is shown in contact with tank 730 and operable to warm the tank 730. When liquid is present in the tank 730, the temperature of the liquid may be controlled as discussed further herein.
The heating element 732 is shown configured as a planar disk or plate arranged below the tank. However, in other embodiments, the heating element may be otherwise in contact with the tank. For example, the heating element may be configured as a hollow cylinder or tubular coil adapted to receive the tank and contact the side walls of the tank. Alternatively, the heating element may be arranged within the tank 730. Typically, the heating element is a direct contact-type heater based on heat arising from electrical resistance. Examples of types of resistive heating elements include metal or ceramic. However, in other embodiments, the heater is an infrared heater.
The system 700 shown in
Optionally, the system can include a plurality of additional chambers or reservoirs. For example, with reference to
However, in embodiments, one or more of the tanks can be built-in, in which case additional fluid inlet ports, heaters and sensors can be built into the tank or walls of the tank. For example, a water liquid inlet port or spray nozzle may be arranged towards the top of the tank 730 so as to aim water downwards at the appliance during filling, rinsing, etc. An egress port can be built into the bottom of the tank to dump the liquid contents of the tank to the waste reservoir by gravity or other pressure action. Surfaces of the tank can include sensor ports that enable detection of oral appliances when the appliances are present in the tank.
The fluid transport network also includes valves 733, 741, 747, 782, 786; pump 731; and various connecting channels or tubes for the liquid to be pumped from one location to another. Preferably, but not necessarily, the components are controlled automatically by the controller described further herein according to the software engines to carry out one or more of the modes. Exemplary modes discussed herein include saliva collection, sanitation, loading and annealing.
Although the tanks 730, 740 are shown having a circular-shaped profile, the profile may vary. Examples of profiles include circular, square, rectangle, arcuate, annular, or a profile to match that of the appliance to be stored.
Floor thickness (t1) may also be relatively large to increase the mass of the tank. In embodiments, t1 ranges from 1 to 10 cm or 1 to 10× that of the sidewall thickness.
However, in other embodiments, the tank wall and floor may be relatively thin (e.g., where active cooling elements are incorporated into the design as described herein). Additionally, features may be combined to provide thin walls and thick floor or vice versa. The shapes and materials are configured to provide or match the temperature profiles described below in connection with the operational modes. For example, the tank is quickly warmed to a target temperature, and then slowly cooled. The thick-walled (or floored) tanks described above serve to more slowly cool the tank and appliances stored therein.
Preferably, the footprint of the restoration system ranges from 6″ by 12″ to 12″ by 24″ and generally is sized to fit on a residential bathroom countertop adjacent the sink. However, it is to be understood the invention may vary widely and the shapes, size, materials, and component arrangement are not intended to be limited except as recited in any appended claims.
Unlike the appliance restoration system 700 described in
A heating element (not shown) can be arranged to contact tank 830 and operable to adjust the temperature of the tank 830, and contents contained therein. The heating element or module may be of similar construction to that described herein.
Except where doing so would be exclusive to one another, any of the components described herein may be incorporated into any of the embodiments described herein to transport liquid to and from the various liquid tanks/receptacles, etc. Additionally, the valves may be electronically operable to open and close via the computer or processor, user input device, or software engine and modules, described further herein. Indeed, the number and arrangement of the tanks, reservoirs, pumps, heating elements, accessory agent compartments, specimen collectors, valves, connecting tubes, and ports may vary widely and the invention is only intended to be limited as recited in any appended claims.
An exemplary multi-stage appliance rejuvenation process in accordance with an embodiment of the invention comprises the following steps: (a) placing an aligner (or aligner set) in the main tank (e.g., 730, 830); (b) closing the lid and turning on the power by pressing button 712, 812; (c) toggling the mode setting button 716, 816 to select the desired mode(s). In embodiments, modes include any one or combination of the following: (i) cleaning/sanitation, (ii) active ingredient loading, (iii) restoring/annealing, (iv) sensing, and (v) specimen collecting.
Cleaning/sanitation Mode. In a cleaning/sanitation mode in accordance with embodiments of the invention, the rejuvenation tank 730, 830 is initially filled with liquid (e.g., water) whether manually or automatically as described herein. The cleaning/sanitation mode controls the water temperature according to a time temperature profile, an example of which is shown in
Preferably, a cleaning agent is added to the tank prior to activation to kill germs, freshen, and generally clean the aligner. Examples of cleaning agents are, without limitation, Sodium Bicarbonate, Sodium Carbonate, Sorbitol, Potassium Monopersulfate, Sodium Perborate Monohydrate, Ethylenediaminetetraacetic Acid, Polyethylene Glycol, Sodium Benzoate, Sodium Lauryl Sulfoacetate, Spearmint Flavor, FD&C Blue #1, Polident (denture cleaner). Mouthwash and cleaners containing alcohol are less desirable, or should be avoided altogether.
The cleaning agent may be added by hand. Optionally, embodiments of the invention arrange a cleaning agent compartment in the system (e.g., chamber 745 shown in
Additionally, the cleaning or sanitation mode preferably includes one or more rinses using clean water (free of the cleaning agent). After the initial clean, the used water mixture may be transported to another tank or reservoir, or otherwise ejected from the main tank 730, 830. The tank is reloaded with clean water sans cleaning agent. The cleaning mode optionally agitates the liquid and optionally carries out the temperature time cleaning profile described above. However, in embodiments, rinses may be performed without heating/cooling and without agitation.
Subsequent to the cleaning and rinsing actions, the used water is dumped out, fed to another tank, or drained to a lower reservoir (e.g., waste chamber 780, reservoir 834 shown in
Loading Mode. In a loading mode, the appliance is loaded with an active ingredient (AI). Categories of AI agents include, without limitation, fluorides, flavors (e.g., mint), health supplements (e.g., vitamins, minerals and enzymatic pre-cursors such as melatonin, 5-HTP), and dental-related wellness agents.
In a loading mode, water and the AI are added to the main chamber manually by hand or automatically as described herein. In embodiments, the system can include a dedicated AI chamber that is connected to the main tank via the fluid transport network. The controller is operable to control the valves and pump to transport the AI and water to the main tank.
In embodiments, the loading mode adjusts the temperature of the water according to the time temperature profile. An example of a preferred loading time temperature profile is shown in
Optionally, The AI agent compartment is preloaded with the agent and the controller is operable to automatically deliver a dose(s) according to a time schedule during the loading cycle. Additionally, the controller, described herein, may be configured to control and evaluate the status of the AI agent compartment. For example, the compartment may include a sensor, and when the compartment is low, the system indicates to add more agent. Indication may be via the light indicator, or an alert through the network access device (e.g., 330, 370).
Restoring Mode. In a restoring mode in accordance with embodiments of the invention, liquid in the tank is drained, dumped or otherwise evacuated as described herein. Optionally, one or more rinse cycles may be performed to rinse the appliance.
In the restoring mode, heat is applied to the dry tank for a predetermined amount of time to heat the appliance to a predetermined appliance restore/annealing temperature. An example of an annealing time temperature profile is shown in
Without intending to being bound to theory, annealing involves slowly heating a polymer part to a temperature below its softening point at a controlled rate, holding it at that elevated temperature for a certain amount of time, and then allowing it to slowly cool back to room temperature. When the part is reheated according to such a time temperature profile, the material relaxes and the internal stress is reduced. In embodiments of the invention, annealing serves to return the aligner to its preset or initial shape.
Exemplary appliance annealing temperatures range from 60 to 80 degrees Celsius at the “onset temperature” or 5 to 15% below the softening temperature of the appliance. If the appliance has multiple layers of different materials, the annealing temperature would preferably range between 5 to 15% below the softening temperature of the material having the greatest impact on the pre-set shape of the appliance.
In embodiments of the invention, the processor is programmed to prompt the user to input the appliance model number, polymer layer characteristics, or type and to apply a matching annealing temperature time profile from a database of annealing temperature time profiles. In some embodiments, the processor is programmed to compute a custom annealing temperature time profile for the instant appliance based on its number of layers, type of material in each layer, thickness of each layer, and extrapolating data from known temperature time profiles of similar appliances.
Exemplary annealing time periods range from 3-8 hours, and more preferably 2-4 hours or under 5 hours.
Sensing Mode. The sensing mode may be performed as described herein in connection with, e.g.,
Specimen Collection Mode. The specimen collection mode is preferably performed prior to the sanitation/cleaning modes in order to collect saliva residue from the appliance before it is cleaned. To this end, the worn appliance is placed in an empty tank (e.g., tank 730). Clean (namely, deionized) water is added to the tank, rinsing the appliance. The clean water may be added manually by hand (e.g., the user sprays or pours DI over the appliance) or the fluid transport network described above can automatically deliver water over the appliance once the collection mode is activated by the user.
Regardless of the technique employed to deliver the clean water, the controller, valves, and optionally pump are operable to transport the saliva water mixture to the removable collector 743.
The user may then manually remove the collector 743 from the system 700 for analysis, where it may be sent to a lab for analysis. The sample may be screened for various analytes, bacteria, diseases, viruses, wellness, and other conditions related to the health of the wearer.
Alternatively, the sensor and detectors described herein are incorporated or built into the collector chamber for onboard analysis of the saliva. Data from the sensors and detectors, if built in, is sent to the sensor module and engine for evaluation as described herein. Indeed, components and software programs may be shared by different modes where possible.
Restore module 905 can include a heating device or source as described above for heating an appliance held in the rejuvenation tank. The restore module 905 may comprise a controller, heating element, cooling element (e.g., refrigerator coils, Peltier module, or fan), and temperature sensor(s). Examples of heating/cooling elements include resistance-based heaters, infrared heaters, and thermoelectric circuits (e.g., Peltier modules). Combinations of the heating elements can be arranged to contact the tanks to heat and/or cool the tank(s). An example of a temperature sensor is a thermocouple. Thermocouples may be arranged with the heating element itself, against the tank(s), inside the tank, or otherwise to measure or estimate the temperature of the tank, liquid or appliance therein.
In embodiments, restore engine 910 is a program or part of the processing system 110 operable to control the restore module 905. In embodiments, the restore engine and module are based on user input. The user input can include power button 712, 812 for powering on the unit and mode setting button 716, 816 for toggling to the rejuvenation mode. Rejuvenation engine 910 can be operable to control the rejuvenation module 905 to initiate a rejuvenation/restoring cycle according to a schedule or by detecting an event. For example, when an appliance is placed within the appliance holder, a cycle will be initiated.
In embodiments, once the cycle begins, the restore engine and module operate to heat and cool the rejuvenation tank and appliance according to the predetermined temperature time profile (e.g., the time temperature profile shown in
Load module 920 can include a heating device or source as described above for heating an appliance held in the rejuvenation tank. The load module 920 may comprise a heater including a controller, temperature sensor(s), and/or heating element. In embodiments, the load module and restore module share the same heating element and temperature sensors for controlling the power of the heater. Additionally, in embodiments, the load module may comprise an AI agent compartment which can be pre-filled with the AI agent. During operation, the loading engine is programmed to open the AI agent compartment to deliver the AI agent to the rejuvenation tank. The loading module may also include a device for agitating the liquid in the tank as described above.
In embodiments, the load engine 925 is a program or part of the processing system 110 operable to control the components of the load module 920 according to a predetermined cycle or user input. In embodiments, the user input can include power button 712,812 for powering on the unit and mode setting button 716,816 for toggling to the mode. Additionally, loading engine 925 can be operable to control the loading module 920 to initiate a loading cycle according to a schedule, or by detecting an event. For example, when an appliance is placed within appliance holder, a cycle will be initiated.
In a preferred embodiment, the sanitation module 205 described above is operable to clean, rinse, or sterilize the appliance in the main tank.
Sanitation module 205 can include a heating device or source as described above for heating an appliance and liquid held in the rejuvenation tank. The sanitation module 205 may comprise a heater including a controller, temperature sensor(s), and/or heating element. In embodiments, the sanitation module and restore module share the same heating element and temperature sensors for controlling the power of the heater. Additionally, in embodiments, the sanitation module may comprise a cleaning agent compartment (e.g., chamber 745 shown in
After the cleaning time-temperature cycle has been completed, the liquid is drained. Preferably, the appliance is rinsed with clean water.
In embodiments, as described above, the sanitation module and engine are programmed to sterilize the appliance by, e.g., applying indirect energy to the appliance. Ultrasound or electromagnetic (EM) radiation (e.g., ultraviolet radiation) may be aimed at the appliance to kill bacteria.
In embodiments, the sanitation engine 114 is a program or part of the processing system 110 operable to control the components of the sanitation module 205 according to a predetermined cycle or user input. In embodiments, the user input can include power button 712, 812 for powering on the unit and mode setting button 716, 816 for toggling to the mode. Additionally, sanitation engine 114 can be operable to control the sanitation module 205 to initiate a sanitation cycle (clean, sterilize, agitate, etc.) according to a schedule, or by detecting an event. For example, when an appliance is placed within appliance holder, a cycle will be initiated.
In a preferred embodiment, the sensing module described above detects for a threshold level of loading agent present in the aligner when the aligner is deposited in the holder. If the sensed AI level is below the threshold level, the loading cycle is automatically commenced or scheduled to load or top off the aligner with the desired AI agent based on the amount of AI detected.
In embodiments, once the cycle begins, the load engine and module operate to heat the rejuvenation tank and appliance according to the predetermined temperature time profile (e.g., the time temperature profile shown in
Each of the engines 112, 114, 118, 910, 925 is operable to output data to records engine 116 for the purpose of creating rejuvenation records by records engine 116. Rejuvenation engine 910 can output a signal to indicator light 210, 714, 814 to provide a visual indication to the user that the rejuvenation process is underway or an error has occurred that prevents completion of the rejuvenation process. Collectively, a wide range of records may be created and provided to the user arising from the rejuvenation system including but not limited to statistics on compliance (namely, user wear time), sanitizing or cleaning (e.g., cleaning time, cleaning complete, sterilized complete), loading (e.g., loading time, loading complete, AI-type detected, AI-type level), annealing (e.g., annealing or heating time, annealing complete), wellness (e.g., hydration level, Cushing's disease, anovulation, HIV, cancer, parasites, hypogonadism, allergies, hepatitis A virus, hepatitis B virus, hepatitis C. virus). Such records may be sent via the communication modules to the user directly or via LAN or cloud-based network.
In embodiments, wireless communication module is configured to communicate with a wide range of wireless devices including smart phones and tablets which can be programmed with custom software (e.g., an App) to operate the rejuvenation system, check status and progress of modes, view records as described above including, e.g., wear usage and health indicators, receive alerts and rewards, and input patient data, preferences, and instructions.
It is also to be understood that the various components, cycles and processes described herein can be combined in any logical order or manner except where exclusive to one another. For example, the sanitizing module may clean the aligner prior to, contemporaneously, or after rejuvenation or annealing is performed. Hardware such as the tanks, heating elements, cooling elements, and sensors may be shared by the various modules. For example, the sanitation, loading, restoring module may share the heating element. Indeed, the invention is intended to include a wide range of combinations and configurations to carry out the objects described herein.
With reference to
Special-purpose computer system 1100 comprises a computer 1102, a monitor 1106 coupled to computer 1102, one or more additional user output devices 1130 (optional) coupled to computer 1102, one or more user input devices 1140 (e.g., keyboard, mouse, track ball, touch screen) coupled to computer 1102, an optional communications interface 1150 coupled to computer 1102, a computer-program product 1105 stored in a tangible computer-readable memory in computer 1102. Computer-program product 1105 directs computer system 1100 to perform the above-described methods. Computer 1102 may include one or more processors 1160 that communicate with a number of peripheral devices via a bus subsystem 1190. These peripheral devices may include user output device(s) 1130, user input device(s) 1140, communications interface 1150, and a storage subsystem, such as random-access memory (RAM) 1170 and non-volatile storage drive 1180 (e.g., disk drive, optical drive, solid state drive), which are forms of tangible computer-readable memory.
Computer-program product 1105 may be stored in non-volatile storage drive 1180 or another computer-readable medium accessible to computer 1102 and loaded into random access memory (RAM) 1170. Each processor 1160 may comprise a microprocessor, such as a microprocessor from Intel® or Advanced Micro Devices, Inc.®, or the like. To support computer-program product 1105, the computer 1102 runs an operating system that handles the communications of computer-program product 1105 with the above-noted components, as well as the communications between the above-noted components in support of the computer-program product 1105. Exemplary operating systems include Windows® or the like from Microsoft Corporation, Solaris® from Sun Microsystems, LINUX, UNIX, and the like. User input devices 1140 include all possible types of devices and mechanisms to input information to computer 1102. These may include a keyboard, a keypad, a mouse, a scanner, a digital drawing pad, a touch screen incorporated into the display, audio input devices such as voice recognition systems, microphones, and other types of input devices. In various embodiments, user input devices 1140 are typically embodied as a computer mouse, a touch screen, wireless remote, a drawing tablet, or a voice command system. User input devices 1140 typically allow a user to select objects, icons, text and the like that appear on the monitor 1106 via a command such as a click of a button or the like. User output devices 1130 include all possible types of devices and mechanisms to output information from computer 1102. These may include a display (e.g., monitor 1106), printers, non-visual displays such as audio output devices, etc. Communications interface 1150 provides an interface to other communication networks, such as communication network 1195, and devices and may serve as an interface to receive data from and transmit data to other systems, WANs and/or the Internet. Embodiments of communications interface 1150 typically include an Ethernet card, a modem (telephone, satellite, cable, ISDN), a (asynchronous) digital subscriber line (DSL) unit, a FireWire® interface, a USBC® interface, a wireless network adapter, and the like. For example, communications interface 1150 may be coupled to a computer network, to a FireWire® bus, or the like. In other embodiments, communications interface 1150 may be physically integrated on the motherboard of computer 1102, and/or may be a software program, or the like.
RAM 1170 and non-volatile storage drive 1180 are examples of tangible computer-readable media configured to store data such as computer-program product embodiments of the present invention, including executable computer code, human-readable code, or the like. Other types of tangible computer-readable media include floppy disks, removable hard disks, optical storage media such as CD-ROMs, DVDs, bar codes, semiconductor memories such as flash memories, read-only-memories (ROMs), battery-backed volatile memories, networked storage devices, and the like. RAM 1170 and non-volatile storage drive 1180 may be configured to store the basic programming and data constructs that provide the functionality of various embodiments of the present invention, as described above. Software instruction sets that provide the functionality of the present invention may be stored in RAM 1170 and non-volatile storage drive 1180. These instruction sets or code may be executed by the processor(s) 1160. RAM 1170 and non-volatile storage drive 1180 may also provide a repository to store data and data structures used in accordance with the present invention.
RAM 1170 and non-volatile storage drive 1180 may include a number of memories including a main random-access memory (RAM) to store instructions and data during program execution and a read-only memory (ROM) in which fixed instructions are stored. RAM 1170 and non-volatile storage drive 1180 may include a file storage subsystem providing persistent (non-volatile) storage of program and/or data files. RAM 1170 and non-volatile storage drive 1180 may also include removable storage systems, such as removable flash memory. Bus subsystem 1190 provides a mechanism to allow the various components and subsystems of computer 1102 to communicate with each other as intended. Although bus subsystem 1190 is shown schematically as a single bus, alternative embodiments of the bus subsystem may utilize multiple busses or communication paths within the computer 1102.
Throughout the foregoing description, and for the purposes of explanation, numerous specific details are set forth in order to provide a thorough understanding of the described techniques. It will be apparent, however, to one skilled in the art that these techniques can be practiced without some of these specific details. Although various embodiments that incorporate these teachings have been shown and described in detail, those skilled in the art could readily devise many other varied embodiments or mechanisms to incorporate these techniques. Also, embodiments can include various operations as set forth above, fewer operations, or more operations; or operations in another order than that specifically described above. Additionally, any of the components and steps described herein may be combined with one another in any logical manner except where such components or steps would be exclusive to one another. Accordingly, the scope and spirit of the invention should be judged in terms of the claims, which follow as well as the legal equivalents thereof.
This claims priority to provisional patent application No. 63/336,846, filed Apr. 29, 2022, and entitled “ORAL APPLIANCE RESTORATION SYSTEM”.
| Number | Date | Country | |
|---|---|---|---|
| 63336846 | Apr 2022 | US |
