Claims
- 1. A method for obtaining oral fluid that contains substances for testing comprising:
- providing a device which comprises an absorbent pad for recovering a test substance from oral fluid; a syringe having a barrel, a plunger having an inner end to which the absorbent pad is attached, a fluid passageway at the outlet end of the barrel, and a detection reagent means contained in said passageway, effective to be released into the oral fluid when oral fluid is expelled from the barrel;
- applying oral fluid to said absorbent pad;
- extracting said oral fluid from said pad by depressing said plunger; and
- causing said oral fluid to pass through said passageway whereby said detection reagent means is released into said oral fluid.
- 2. The method of claim 1, wherein said pad is impregnated with the salts of a hypertonic solution.
- 3. The method of claim 2, wherein the test substance is an antibody, and the hypertonic solution includes about 3.5% sodium chloride, about 0.3% citric acid, about 0.1% potassium sorbate, about 0.1% sodium benzoate, and about 0.1% bovine gelatin.
- 4. The method of claim 1, wherein the barrel has a radially enlarged opening through which the plunger is received.
- 5. The method of claim 1, wherein the fluid passageway is defined by a cartridge that is detachably mounted on the barrel.
- 6. The method of claim 1, wherein the reagent means includes reagents effective to react with a test substance in the oral fluid to produce a detectable color change.
- 7. The method of claim 1, wherein the detection reagent means includes reagents effective to react with and agglutinate a test substance in the oral fluid to produce a detectable precipitate.
- 8. The method of claim 1, which further includes an absorbent strip in fluid communication with the passageway, said strip containing detecting reagents effective to produce a detectable color change when the strip is wetted by the oral fluid, when a test substance is present in the oral fluid.
Parent Case Info
This is a continuation of application Ser. No. 08/099,926, filed Aug. 3, 1993, now U.S. Pat. No. 5,477,437, which is a continuation-in-part of Ser. No. 07/935,845, filed Aug. 25, 1992, now U.S. Pat. No. 5,339,829, which is a continuation-in-part of Ser. No. 07/865,054, filed Apr. 8, 1992, now abandoned, which is a continuation-in-part of Ser. No. 07/641,739, filed Jan. 15, 1991, now U.S. Pat. No. 5,103,836, which is a continuation-in-part of Ser. No. 07/486,415, filed Feb. 28, 1990, now abandoned, which is a continuation-in-part of Ser. No. 07/410,401, filed Sep. 21, 1989, now U.S. Pat. No. 5,022,409.
US Referenced Citations (9)
Foreign Referenced Citations (2)
Number |
Date |
Country |
0414513A3 |
Feb 1991 |
EPX |
WO9113355 |
Sep 1991 |
WOX |
Continuations (1)
|
Number |
Date |
Country |
Parent |
99926 |
Aug 1993 |
|
Continuation in Parts (5)
|
Number |
Date |
Country |
Parent |
935845 |
Aug 1992 |
|
Parent |
865054 |
Apr 1992 |
|
Parent |
641739 |
Jan 1991 |
|
Parent |
486415 |
Feb 1990 |
|
Parent |
410401 |
Sep 1989 |
|