The present disclosure relates generally to the field of medical devices. More particularly, some embodiments relate to osteotomes that are configured for simultaneous advancement and articulation of a distal portion of the osteotome. Related methods and systems are also disclosed.
The written disclosure herein describes illustrative embodiments that are non-limiting and non-exhaustive. Reference is made to certain of such illustrative embodiments that are depicted in the figures, in which:
An osteotome may be used to create or expand a cavity within bone of a patient. For example, in some embodiments, a distal portion of an osteotome may be inserted into a bone (e.g., a vertebra) of the patient. Once the distal portion of the osteotome is disposed within the bone of the patient, the distal portion of the osteotome may be displaced. Such displacement may cut, grind, granulate, fragmentize, deform, displace, or otherwise alter the bone, thereby creating and/or expanding a cavity within the bone.
As the distal portion of the osteotome is displaced, the bone of the patient may exert one or more forces on the distal portion of the osteotome. For example, in some embodiments where the distal portion of the osteotome is transitioned from a linear configuration to a bent configuration without simultaneous advancement of the distal portion of the osteotome in a distal direction, the distal portion of the osteotome may contact bone that exerts one or more reactionary forces on the distal portion. Such force(s) may damage or weaken the osteotome.
In some embodiments described herein, the osteotome may be manipulated such that a distal portion of the osteotome is simultaneously advanced and articulated. For example, in some embodiments, rotation of a handle may cause the distal portion of the osteotome to simultaneously both (1) be advanced within the bone of the patient and (2) bend away from a longitudinal axis of the osteotome. Relative to other methods, the simultaneous advancement and articulation of a distal portion of an osteotome may reduce the magnitude of one or more forces that may act on the distal portion of the osteotome. Stated differently, simultaneous advancement and articulation of the distal portion may reduce one or more forces on the distal portion of the osteotome relative to other methods in which advancement and articulation are separated in time, thereby decreasing the risk of breakage or other damage to the osteotome.
The components of the embodiments as generally described and illustrated in the figures herein can be arranged and designed in a wide variety of different configurations. Thus, the following more detailed description of various embodiments, as represented in the figures, is not intended to limit the scope of the present disclosure, but is merely representative of various embodiments. While various aspects of the embodiments are presented in drawings, the drawings are not necessarily drawn to scale unless specifically indicated.
The phrase “coupled to” is broad enough to refer to any suitable coupling or other form of interaction between two or more entities. Two components may be coupled to each other even though they are not in direct contact with each other. For example, two components may be coupled to each other through an intermediate component. Two components are “fixedly coupled” to each other if neither component is displaceable relative to the other. The phrase “attached to” refers to interaction between two or more entities which are in direct contact with each other and/or are separated from each other only by a fastener of any suitable variety (e.g., an adhesive).
The terms “proximal” and “distal” are opposite directional terms. For example, the distal end of a device or component is the end of the component that is furthest from the practitioner during ordinary use. The proximal end refers to the opposite end, or the end nearest the practitioner during ordinary use.
As shown in
The handle 102 may be coupled to the first shaft 120 such that rotation of the handle 102 results in rotation of the first shaft 120. In some embodiments, the handle 102 is coupled to the first shaft 120 such that when the handle 102 is rotated, the first shaft 120 rotates at the same rate as the handle 102. Stated differently, as the handle 102 is rotated 360 degrees about a longitudinal axis (l), the first shaft 120 may also rotate 360 degrees about the longitudinal axis (l).
In the depicted embodiment, the handle 102 is coupled to the first shaft 120 by inserting a hexagonal proximal portion 123 of the first shaft 120 into a complementary hexagonal opening 106 on the handle 102. A fastener 104 (e.g., a bolt) may then be inserted through the handle 102 into a proximal opening 121 of the first shaft 120 such that the fastener 104 is threadably engaged with interior threads 129 disposed adjacent to a proximal end of the first shaft 120. In some embodiments, a washer 103 is disposed between the fastener 104 and the handle 102.
The housing 110 may be generally elongate in shape. In the depicted embodiment, the housing 110 includes interior threads 112 disposed adjacent the proximal end of the housing 110, a recess 116, a distal adaptor 107, proximal exterior threads 114, and distal exterior threads 115. The distal adaptor 107 (e.g., a male luer connection) may be configured to facilitate attachment to an introducer that has been inserted into a patient. The housing may encompass or partially encompass various components, such as the shuttle 160, the casing 170, and the second shaft 130.
In some embodiments, the housing 110 is formed from two separate portions (see
The first shaft 120 may include exterior threads 124. The exterior threads 124 may threadably engage with the interior threads 112 of the housing 110 such that the first shaft 120 is threadably coupled to the housing 110. Due to the threaded interaction between the first shaft 120 and the housing 110, rotation of the handle 102 in a first (e.g., clockwise) direction may cause simultaneous rotation of the first shaft 120, thereby distally displacing the first shaft 120 with respect to the housing 110. As discussed below, the exterior threads 124 may have a pitch that is greater than the pitch of exterior threads 132 on the second shaft 130. In some embodiments, the exterior threads 124 of the first shaft 120 form a right-handed helix.
The first shaft 120 may be coupled to the shuttle 160 that is disposed within the housing 110. For example, the shuttle 160 may be rotatably (but not threadedly) coupled to the first shaft 120 such that rotation of the first shaft 120 in a first (e.g., clockwise) direction with respect to the housing 110 results in axial displacement of the shuttle 160 relative to the housing 110. More particularly, an inward-projecting ridge 166 adjacent the proximal end of the shuttle 160 may be disposed within an exterior slot 127 of the first shaft 120 such that axial displacement of the first shaft 120 results in an equal magnitude of axial displacement of the shuttle 160. In some embodiments, the shuttle 160 is formed from two separate components (e.g., halves) that are attached to one another, such as via screws 111.
The shuttle 160 may further include an aperture 162. The aperture 162 may be configured to permit extension of an arm of the casing 170 through the shuttle 160 for interaction with a recess 116 of the housing 110 as described in further detail below. The shuttle 160 may also include one or more recesses 164 that are designed to accommodate (e.g., secure) an anchor 142 at the proximal end of the third shaft 140. The shuttle 160 may be configured to travel back and forth within the housing 110 along the longitudinal axis of the medical device 100.
In some embodiments, the first shaft 120 further includes an inner sleeve 126 disposed adjacent to the distal end of the first shaft 120. The inner sleeve 126 may be coupled to the remainder of the first shaft 120 such that the inner sleeve 126 and the first shaft 120 rotate at the same rate. In other words, the inner sleeve 126 may be fixedly coupled to a remainder of the first shaft 120. The inner sleeve 126 may have a composition that differs from the composition of the remainder of the first shaft 120. For example, in some embodiments, the inner sleeve 126 is formed from a metal or metal alloy, while the remainder of the first shaft 120 is formed from a synthetic polymer (e.g., a plastic). The composition of the inner sleeve 126 may provide increased durability relative to the composition of the remainder of the first shaft 120. In other embodiments, there is no separate inner sleeve 126.
The first shaft 120 may further include interior threads 122 that are disposed adjacent the distal end of the first shaft 120. In the depicted embodiment, the interior threads 122 are disposed on an interior of the inner sleeve 126.
The second shaft 130 may be threadably coupled to the first shaft 120. For example, in the depicted embodiment, the interior threads 122 adjacent the distal end of the first shaft 120 may threadably engage with the exterior threads 132 of the second shaft 130. The interior threads 122 of the first shaft 120 and the exterior threads 132 of the second shaft 130 may each have a shorter pitch than the exterior threads 124 of the first shaft 120 and the interior threads 112 of the housing 110. In some embodiments, the exterior threads 132 of the second shaft 130 form a right-handed helix.
As the first shaft 120 is rotated in a first (e.g., clockwise) direction, the second shaft 130 may be prevented from rotating about the longitudinal axis (l) of the medical device by the casing 170 described in greater detail below. Thus, rotation of the first shaft 120 in a first direction may cause the first shaft 120 to move distally with respect to the second shaft 130 due to the difference in pitch between the threads 122, 132, and the threads 124, 112. Thus, rotation of the first shaft 120 with respect to the housing 110 may result in axial displacement of the casing 170 relative to the shuttle 160.
As shown in
The casing 170 may include one or more arms that are configured to interact with one or more recesses 116 within the housing 110. For example, in some embodiments, each arm of the T-shaped casing 170 may extend though an aperture 162 in the shuttle 160 to the recess 116 within the housing 110. The recess(es) 116 of the housing 110 may interact with the casing 170 to prevent rotation of both the casing 170 and the second shaft 130 relative to the housing 110.
The third shaft 140 may be a metallic shaft that extends from a proximal anchor 142 that is disposed (e.g., secured) within the recess(es) 164 of the shuttle 160 to a position at or adjacent to the distal end of the medical device 100. The third shaft 140 may include an elongate lumen that extends from a proximal opening in the anchor 142 to adjacent the distal end of the medical device 100. In some embodiments, the third shaft 140 may include a plurality of slots 144 (see
The fourth shaft 150 may be a metallic shaft that extends distally from the bulbous proximal end 152 within the casing 170 to a position at or adjacent to the distal end of the medical device 100. In some embodiments, the fourth shaft 150 includes an elongate lumen. Like the third shaft 140, the fourth shaft 150 may include a plurality of slots 154 adjacent its distal end. In some embodiments, the slots 154 may be disposed opposite the slots 144 of the third shaft 140.
The fourth shaft 150 may be at least partially disposed within an elongate lumen of the third shaft 140. Stated differently, the third shaft 140 may be disposed around a distal portion of the fourth shaft 150.
The third shaft 140 and the fourth shaft 150 may together form an articulating distal portion 108 of the medical device 100. As shown in
The medical device 100 may be used in one or more medical procedures, such as procedures for creating or expanding a cavity within bone of a patient. Various stages of an exemplary procedure for creating or expanding a cavity within bone of a patient are shown in
An exemplary medical procedure may involve obtaining a medical device, such as the medical device 100 (e.g., an osteotome) and inserting a distal region (e.g., a pointed distal tip) of the medical device 100 into bone of a patient. For instance, in some embodiments, a distal region of the medical device 100 is inserted through an introducer 5 into a vertebral body (see
Once the distal end of the medical device 100 is disposed within bone of the patient (e.g., as shown in
Due to the interaction between the inward-projecting ridge 166 of the shuttle 160 and the exterior slot 127 of the first shaft 120, rotation of the first shaft 120 also causes the shuttle 160 to move distally with the first shaft 120 along the longitudinal axis (l) of the medical device 100. Stated differently, as a result of rotational input at the handle 102, the first shaft 120 and the shuttle 160 may move distally within the housing 110 at the same rate. In the depicted embodiment, the shuttle 160 does not rotate within the housing 110 about the longitudinal axis (l) of the medical device 100. Rather, because (1) the casing 170 does not rotate relative to the housing 110 due to the interaction between arms of the casing 170 and the recess 116 within the housing 110 and (2) rotation of the shuttle 160 is constrained by the casing 170, the shuttle 160 of the depicted embodiment cannot rotate about the longitudinal axis (l) of the medical device 100. Stated differently, rotation of the first shaft 120 relative to the housing 110 causes rotation of the inward-projecting ridge 166 within the exterior slot 127 of the first shaft 120.
Furthermore, as the proximal anchor 142 of the third shaft 140 is disposed within the recess 164 of the shuttle 160, the proximal portion of the third shaft 140 moves distally with both first shaft 120 and the housing 110. Stated differently, each of the first shaft 120, the shuttle 160, and the proximal portion third shaft 140 may move axially (e.g., distally) relative to the housing 110 at a first rate. In other words, the shuttle 160 and the third shaft 140 may be coupled to the first shaft 120 such that axial displacement of the first shaft 120 a first distance relative to the housing 110 results in axial displacement of the third shaft 140 and the shuttle 160 a distance relative to the housing 110 that is equal to the first distance.
Additionally, as the first shaft 120 is rotated relative to the housing 110, the interior threads 122 adjacent the distal end of the first shaft 120 may interact with the exterior threads 132 of the second shaft 130. More specifically, as the first shaft 120 is rotated relative to the housing 110, the first shaft 120 may be distally displaced relative to the second shaft 130 due to the interaction between the interior threads 122 of the first shaft 120 and the exterior threads 132 of the second shaft 130. Like the shuttle 160, the second shaft 130 in the depicted embodiment does not rotate within the housing 110 about the longitudinal axis (l) of the medical device 100. Rather, the second shaft 130 is fixedly coupled to the casing 170 and is thereby rotationally constrained within the housing 110. Thus, as a result of being rotationally constrained in this manner, rotation of the first shaft 120 causes the second shaft 130 to move proximally relative to the first shaft 120. Further, as the pitch of the exterior threads 124 of the first shaft 120 and the interior threads 112 of the housing 110 is greater than the pitch of the interior threads 122 and the exterior threads 132, the first shaft 120 may move both (1) proximally relative to the shuttle 160 and (2) distally relative to the housing 110. Stated differently, as the handle 102 is rotated, the second shaft 130 may move distally within the housing 110 at a second rate that is different (e.g., slower) than the first rate at which the first shaft 120, the shuttle 160, and/or the proximal portion of the third shaft 140 move distally within the housing 110. In this manner, the fourth shaft 150 may be coupled to the second shaft 130 such that axial displacement of the second shaft 130 a second distance relative to the housing 110 results in axial displacement of the fourth shaft 150 a distance relative to the housing 110 that is equal to the second distance.
As (1) the casing 170 is fixedly coupled to the second shaft 130 and (2) the fourth shaft 150 is coupled to the casing 170 due to the position of the bulbous proximal end 152 within the pockets of the casing 170, the casing 170 and the proximal portion of the fourth shaft 150 may move axially (e.g., distally) with the second shaft. Stated differently, the second shaft 130 and the fourth shaft 150 may move distally within the housing 110 at a second rate that is slower than the rate at which both the first shaft 120 and the proximal portion of the third shaft 140 move distally with respect to the housing 110.
As the proximal portion of the third shaft 140 moves distally with respect to the housing 110 at a rate that is greater than the rate at which the fourth shaft 150 moves distally with respect to the housing 110, a distal portion of the medical device 100 may transition from a linear configuration (
For example, as the distance between the proximal anchor 142 of the third shaft 140 and the proximal bulbous end 152 of the fourth shaft 150 increases, the distal tip of the medical device 100 may be simultaneously displaced both (1) distally relative to the housing 110 and (2) laterally relative to the longitudinal axis of the medical device 100. Stated differently, as a result of rotation of the first shaft 120 relative to the housing 110, (1) the distal portion 108 of the medical device 100 may be articulated such that a distal tip of the medical device 100 is laterally displaced relative to a longitudinal axis (l) of the medical device 100 and (2) the distal portion 108 of the medical device 100 is displaced in an axial (e.g., distal) direction relative to the housing 110.
In the depicted embodiment, as the first shaft 120 is rotated relative to the housing 110, the distal portion 108 of the medical device 100 may transition from a linear configuration to a non-linear configuration such that (1) the slots 144 on the third shaft 140 are disposed on a concave side of a bend and (2) the slots 154 on the fourth shaft 150 are disposed on a convex side of the bend (see
In some embodiments, the process described above is reversible. Stated differently, the medical device 100 may transition from the non-linear configuration to the linear configuration by rotating the handle 102 and/or the first shaft 120 in a second direction (e.g., counterclockwise) that differs from the first direction.
Any methods disclosed herein include one or more steps or actions for performing the described method. The method steps and/or actions may be interchanged with one another. In other words, unless a specific order of steps or actions is required for proper operation of the embodiment, the order and/or use of specific steps and/or actions may be modified. Moreover, sub-routines or only a portion of a method described herein may be a separate method within the scope of this disclosure. Stated otherwise, some methods may include only a portion of the steps described in a more detailed method.
Reference throughout this specification to “an embodiment” or “the embodiment” means that a particular feature, structure, or characteristic described in connection with that embodiment is included in at least one embodiment. Thus, the quoted phrases, or variations thereof, as recited throughout this specification are not necessarily all referring to the same embodiment.
Similarly, it should be appreciated by one of skill in the art with the benefit of this disclosure that in the above description of embodiments, various features are sometimes grouped together in a single embodiment, figure, or description thereof for the purpose of streamlining the disclosure. This method of disclosure, however, is not to be interpreted as reflecting an intention that any claim requires more features than those expressly recited in that claim. Rather, as the following claims reflect, inventive aspects lie in a combination of fewer than all features of any single foregoing disclosed embodiment. Thus, the claims following this Detailed Description are hereby expressly incorporated into this Detailed Description, with each claim standing on its own as a separate embodiment. This disclosure includes all permutations of the independent claims with their dependent claims.
Recitation in the claims of the term “first” with respect to a feature or element does not necessarily imply the existence of a second or additional such feature or element. It will be apparent to those having skill in the art that changes may be made to the details of the above-described embodiments without departing from the underlying principles of the present disclosure.
This application is a divisional of U.S. patent application Ser. No. 15/862,441, filed on Jan. 4, 2018 and titled, “Osteotome with a Distal Portion For Simultaneous Advancement and Articulation,” which claims priority to U.S. Provisional Application No. 62/443,371, filed on Jan. 6, 2017 and titled, “Osteotome with a Distal Portion For Simultaneous Advancement and Articulation,” both of which are hereby incorporated by reference in their entireties.
Number | Name | Date | Kind |
---|---|---|---|
2688329 | Wallace | Sep 1954 | A |
3140623 | Hoose | Jul 1964 | A |
3228400 | Armao | Jan 1966 | A |
3503385 | Stevens | Mar 1970 | A |
3625200 | Muller | Dec 1971 | A |
3664344 | Bryne | May 1972 | A |
3794039 | Kollner et al. | Feb 1974 | A |
3908637 | Doroshow | Sep 1975 | A |
4033331 | Guss et al. | Jul 1977 | A |
4131597 | Bluethgen et al. | Dec 1978 | A |
4236520 | Anderson | Dec 1980 | A |
4276880 | Malmin | Jul 1981 | A |
4294251 | Grennwald et al. | Oct 1981 | A |
4337773 | Raftopoulos et al. | Jul 1982 | A |
4386717 | Koob | Jun 1983 | A |
4399814 | Pratt, Jr. et al. | Aug 1983 | A |
4411266 | Cosman | Oct 1983 | A |
4456017 | Miles | Jun 1984 | A |
4473077 | Noiles | Sep 1984 | A |
4476861 | Dimakos et al. | Oct 1984 | A |
4578061 | Lemelson | Mar 1986 | A |
4586923 | Gould et al. | May 1986 | A |
4595006 | Burke et al. | Jun 1986 | A |
4619263 | Frisbie et al. | Oct 1986 | A |
4627434 | Murray | Dec 1986 | A |
4641654 | Samson et al. | Feb 1987 | A |
4653489 | Tronzo | Mar 1987 | A |
4668295 | Bajpai | May 1987 | A |
4682596 | Bales et al. | Jul 1987 | A |
4719968 | Speros | Jan 1988 | A |
4722948 | Sanderson | Feb 1988 | A |
4731054 | Billeter et al. | Mar 1988 | A |
4742817 | Kawashima et al. | May 1988 | A |
4747840 | Ladika et al. | May 1988 | A |
4748969 | Wardle | Jun 1988 | A |
4784638 | Ghajar et al. | Nov 1988 | A |
4795602 | Pretchel et al. | Jan 1989 | A |
4842603 | Draenert | Jun 1989 | A |
4843112 | Gerhart et al. | Jun 1989 | A |
4846814 | Ruiz | Jul 1989 | A |
4865586 | Hedberg | Sep 1989 | A |
4869906 | Dingeldein et al. | Sep 1989 | A |
4888366 | Chu et al. | Dec 1989 | A |
4900303 | Lemelson | Feb 1990 | A |
4961730 | Bodicky et al. | Oct 1990 | A |
4961731 | Poncy | Oct 1990 | A |
4963151 | Ducheyene et al. | Oct 1990 | A |
4969870 | Kramer et al. | Nov 1990 | A |
4969888 | Scholten et al. | Nov 1990 | A |
4982730 | Royce | Jan 1991 | A |
4998923 | Samson et al. | Mar 1991 | A |
5004501 | Faccioli | Apr 1991 | A |
5017627 | Bonfield | May 1991 | A |
5046513 | O'Leary et al. | Sep 1991 | A |
5049137 | Thompson | Sep 1991 | A |
5049157 | Mittelmeier et al. | Sep 1991 | A |
5059193 | Kuslich | Oct 1991 | A |
5085861 | Gerhart et al. | Feb 1992 | A |
5088991 | Weldon | Feb 1992 | A |
5092891 | Kummer et al. | Mar 1992 | A |
5103804 | Abele | Apr 1992 | A |
5106381 | Chikama | Apr 1992 | A |
5108404 | Scholten et al. | Apr 1992 | A |
5112303 | Pudenz et al. | May 1992 | A |
5114414 | Buchbinder | May 1992 | A |
5116305 | Milder et al. | May 1992 | A |
5147334 | Moss | Sep 1992 | A |
5156606 | Chin | Oct 1992 | A |
5163431 | Greip | Nov 1992 | A |
5184757 | Giannuzzi | Feb 1993 | A |
5188619 | Myers | Feb 1993 | A |
5196201 | Larsson et al. | Mar 1993 | A |
5197971 | Bonutti | Mar 1993 | A |
5211631 | Sheaff | May 1993 | A |
5231989 | Middleman et al. | Aug 1993 | A |
5242082 | Giannuzzi | Sep 1993 | A |
5264214 | Rhee et al. | Nov 1993 | A |
5266248 | Ohtsuka et al. | Nov 1993 | A |
5269750 | Grulke et al. | Dec 1993 | A |
5282821 | Donahue | Feb 1994 | A |
5284128 | Hart | Feb 1994 | A |
5285795 | Ryan et al. | Feb 1994 | A |
5295980 | Ersek | Mar 1994 | A |
5296026 | Monroe et al. | Mar 1994 | A |
5308342 | Sepetka et al. | May 1994 | A |
5322064 | Lundquist | Jun 1994 | A |
5322505 | Krause et al. | Jun 1994 | A |
5334181 | Rubinsky et al. | Aug 1994 | A |
5336699 | Cooke et al. | Aug 1994 | A |
5342356 | Ellman et al. | Aug 1994 | A |
5343877 | Park | Sep 1994 | A |
5352715 | Wallace et al. | Oct 1994 | A |
5356629 | Sander | Oct 1994 | A |
5360416 | Ausherman et al. | Nov 1994 | A |
5368598 | Hasson | Nov 1994 | A |
5372587 | Hammerslag et al. | Dec 1994 | A |
5378234 | Hammerslag et al. | Jan 1995 | A |
5380307 | Chee et al. | Jan 1995 | A |
5385563 | Gross | Jan 1995 | A |
5389073 | Imran | Feb 1995 | A |
5425770 | Piez et al. | Jun 1995 | A |
5431168 | Webster, Jr. | Jul 1995 | A |
5431639 | Shaw | Jul 1995 | A |
5437636 | Snoke et al. | Aug 1995 | A |
5449301 | Hanna et al. | Sep 1995 | A |
5449351 | Zohmann | Sep 1995 | A |
5458597 | Edwards et al. | Oct 1995 | A |
5480382 | Hammerslag et al. | Jan 1996 | A |
5484424 | Cottenceau et al. | Jan 1996 | A |
5489275 | Thompson et al. | Feb 1996 | A |
5496330 | Bates et al. | Mar 1996 | A |
5512610 | Lin | Apr 1996 | A |
5514130 | Baker | May 1996 | A |
5514137 | Coutts | May 1996 | A |
5531715 | Engelson et al. | Jul 1996 | A |
5535922 | Maziarz | Jul 1996 | A |
5549542 | Kovalcheck | Aug 1996 | A |
5549637 | Crainich | Aug 1996 | A |
5549679 | Kuslich | Aug 1996 | A |
5554114 | Wallace et al. | Sep 1996 | A |
5571085 | Accisano, III | Nov 1996 | A |
5571088 | Lennox | Nov 1996 | A |
5574075 | Draemert | Nov 1996 | A |
5599346 | Edwards et al. | Feb 1997 | A |
5616121 | McKay | Apr 1997 | A |
5620447 | Smith et al. | Apr 1997 | A |
5620467 | Wagner | Apr 1997 | A |
5624396 | McNamara et al. | Apr 1997 | A |
5628771 | Mizukawa et al. | May 1997 | A |
5637090 | McGee | Jun 1997 | A |
5637091 | Hakky et al. | Jun 1997 | A |
5662680 | Desai | Sep 1997 | A |
5681282 | Eggers et al. | Oct 1997 | A |
5681289 | Wilcox | Oct 1997 | A |
5681317 | Caldarise | Oct 1997 | A |
5685826 | Bonutti | Nov 1997 | A |
5695513 | Johnson et al. | Dec 1997 | A |
5697281 | Eggers et al. | Dec 1997 | A |
5697536 | Eggers et al. | Dec 1997 | A |
5697909 | Eggers et al. | Dec 1997 | A |
5700157 | Chung | Dec 1997 | A |
5704926 | Sutton | Jan 1998 | A |
5709697 | Ratcliff et al. | Jan 1998 | A |
5725568 | Hastings | Mar 1998 | A |
5735829 | Cherian | Apr 1998 | A |
5741320 | Thornton et al. | Apr 1998 | A |
5766153 | Eggers et al. | Jun 1998 | A |
5800408 | Strauss et al. | Sep 1998 | A |
5810804 | Gough | Sep 1998 | A |
5810867 | Zarbateny et al. | Sep 1998 | A |
5820592 | Hammerslag et al. | Oct 1998 | A |
5833632 | Jacobsen et al. | Nov 1998 | A |
5833692 | Cesarini et al. | Nov 1998 | A |
5847046 | Jiang et al. | Dec 1998 | A |
5849028 | Chen | Dec 1998 | A |
5851212 | Zirps et al. | Dec 1998 | A |
5855577 | Murphy-Chutorian et al. | Jan 1999 | A |
5858003 | Atala | Jan 1999 | A |
5860952 | Quinn | Jan 1999 | A |
5860974 | Abele | Jan 1999 | A |
5876373 | Giba et al. | Mar 1999 | A |
5891027 | Tu | Apr 1999 | A |
5902251 | Vanhooydonk | May 1999 | A |
5902839 | Lautenschlager et al. | May 1999 | A |
5914356 | Erbe | Jun 1999 | A |
5921956 | Grinberg et al. | Jul 1999 | A |
5928239 | Mirza | Jul 1999 | A |
5931829 | Burbank et al. | Aug 1999 | A |
5944715 | Goble et al. | Aug 1999 | A |
5947964 | Eggers | Sep 1999 | A |
5972015 | Scribner et al. | Oct 1999 | A |
5985659 | Kusakabe | Nov 1999 | A |
5997581 | Khalili | Dec 1999 | A |
6019765 | Thornhill et al. | Feb 2000 | A |
6027487 | Crocker | Feb 2000 | A |
6030360 | Biggs | Feb 2000 | A |
6048346 | Reiley et al. | Apr 2000 | A |
6059739 | Baumann | May 2000 | A |
6063078 | Wittkampf | May 2000 | A |
6064902 | Haissaguerre | May 2000 | A |
6066154 | Reiley et al. | May 2000 | A |
6066176 | Oshida | May 2000 | A |
6073051 | Sharkey et al. | Jun 2000 | A |
6080801 | Draenert et al. | Jun 2000 | A |
6099514 | Sharkey et al. | Aug 2000 | A |
6106524 | Eggers et al. | Aug 2000 | A |
6106539 | Fortier | Aug 2000 | A |
6110155 | Baudino | Aug 2000 | A |
6123702 | Swanson | Sep 2000 | A |
6127597 | Beyar et al. | Oct 2000 | A |
6135999 | Fanton et al. | Oct 2000 | A |
6146355 | Biggs | Nov 2000 | A |
6156254 | Andrews et al. | Dec 2000 | A |
6183435 | Bumbalough et al. | Feb 2001 | B1 |
6203507 | Wadsworth et al. | Mar 2001 | B1 |
6203574 | Kawamura | Mar 2001 | B1 |
6228052 | Pohndorf | May 2001 | B1 |
6228904 | Yadav et al. | May 2001 | B1 |
6231569 | Bek et al. | May 2001 | B1 |
6231615 | Preissman | May 2001 | B1 |
6235043 | Reiley et al. | May 2001 | B1 |
6241734 | Scribner et al. | Jun 2001 | B1 |
6248110 | Reiley et al. | Jun 2001 | B1 |
6251092 | Qin et al. | Jun 2001 | B1 |
6258086 | Ashley et al. | Jul 2001 | B1 |
6270476 | Santoianni et al. | Aug 2001 | B1 |
6280413 | Clark et al. | Aug 2001 | B1 |
6280434 | Kinoshita et al. | Aug 2001 | B1 |
6280441 | Ryan | Aug 2001 | B1 |
6280456 | Scribner et al. | Aug 2001 | B1 |
6280473 | Lemperle et al. | Aug 2001 | B1 |
6283960 | Ashley | Sep 2001 | B1 |
6291547 | Lyles | Sep 2001 | B1 |
6312428 | Eggers | Nov 2001 | B1 |
6312454 | Stockel et al. | Nov 2001 | B1 |
6332894 | Stalcup et al. | Dec 2001 | B1 |
6348055 | Preissman | Feb 2002 | B1 |
6352533 | Ellman et al. | Mar 2002 | B1 |
6358251 | Mirza | Mar 2002 | B1 |
6375659 | Erbe et al. | Apr 2002 | B1 |
6383188 | Kuslich et al. | May 2002 | B2 |
6383190 | Preissman | May 2002 | B1 |
6395007 | Bhatnagar et al. | May 2002 | B1 |
6408889 | Komachi | Jun 2002 | B1 |
6409722 | Hoey et al. | Jun 2002 | B1 |
6428894 | Babich et al. | Aug 2002 | B1 |
6437019 | Rusin et al. | Aug 2002 | B1 |
6440138 | Reiley et al. | Aug 2002 | B1 |
6447506 | Swanson et al. | Sep 2002 | B1 |
6447514 | Stalcup et al. | Sep 2002 | B1 |
6464683 | Samuelson et al. | Oct 2002 | B1 |
6478793 | Cosman et al. | Nov 2002 | B1 |
6479565 | Stanley | Nov 2002 | B1 |
6484904 | Horner et al. | Nov 2002 | B1 |
6506217 | Arnett | Jan 2003 | B1 |
6511471 | Rosenman et al. | Jan 2003 | B2 |
6524296 | Beals | Feb 2003 | B1 |
6565588 | Clement et al. | May 2003 | B1 |
6575969 | Rittman et al. | Jun 2003 | B1 |
6575978 | Peterson et al. | Jun 2003 | B2 |
6576249 | Gendler et al. | Jun 2003 | B1 |
6582446 | Marchosky | Jun 2003 | B1 |
6592559 | Pakter et al. | Jul 2003 | B1 |
6599961 | Pienkowski et al. | Jul 2003 | B1 |
6602248 | Sharps et al. | Aug 2003 | B1 |
6607544 | Boucher et al. | Aug 2003 | B1 |
6613054 | Scribner et al. | Sep 2003 | B2 |
6620162 | Kuslich et al. | Sep 2003 | B2 |
6622731 | Daniel et al. | Sep 2003 | B2 |
6623448 | Slater | Sep 2003 | B2 |
6638266 | Wilson et al. | Oct 2003 | B2 |
6638268 | Niazi | Oct 2003 | B2 |
6641587 | Scribner et al. | Nov 2003 | B2 |
6645213 | Sand et al. | Nov 2003 | B2 |
6663647 | Reiley et al. | Dec 2003 | B2 |
6676665 | Foley et al. | Jan 2004 | B2 |
6679886 | Weikel et al. | Jan 2004 | B2 |
6689823 | Bellare et al. | Feb 2004 | B1 |
6692532 | Healy et al. | Feb 2004 | B1 |
6716216 | Boucher et al. | Apr 2004 | B1 |
6719761 | Reiley et al. | Apr 2004 | B1 |
6719773 | Boucher et al. | Apr 2004 | B1 |
6726691 | Osorio et al. | Apr 2004 | B2 |
6730095 | Olson, Jr. et al. | May 2004 | B2 |
6740090 | Cragg et al. | May 2004 | B1 |
6740093 | Hochschuler et al. | May 2004 | B2 |
6743239 | Kuehn et al. | Jun 2004 | B1 |
6746451 | Middleton et al. | Jun 2004 | B2 |
6752863 | Lyles et al. | Jun 2004 | B2 |
6753007 | Haggard et al. | Jun 2004 | B2 |
6770079 | Bhatnagar et al. | Aug 2004 | B2 |
6814734 | Chappuis et al. | Nov 2004 | B2 |
6814736 | Reiley et al. | Nov 2004 | B2 |
6818001 | Wulfman et al. | Nov 2004 | B2 |
6832984 | Stelzer et al. | Dec 2004 | B2 |
6835193 | Epstein et al. | Dec 2004 | B2 |
6837867 | Kortelling | Jan 2005 | B2 |
6863672 | Reiley et al. | Mar 2005 | B2 |
6869430 | Balbierz et al. | Mar 2005 | B2 |
6869445 | Johnson | Mar 2005 | B1 |
6875219 | Arramon | Apr 2005 | B2 |
6881214 | Cosman et al. | Apr 2005 | B2 |
6887246 | Bhatnagar et al. | May 2005 | B2 |
6899715 | Beaty | May 2005 | B1 |
6899719 | Reiley et al. | May 2005 | B2 |
6907884 | Pellegrino et al. | Jun 2005 | B2 |
6913594 | Coleman et al. | Jul 2005 | B2 |
6916306 | Jenkins et al. | Jul 2005 | B1 |
6923813 | Phillips | Aug 2005 | B2 |
6945956 | Waldhauser et al. | Sep 2005 | B2 |
6953594 | Lee et al. | Oct 2005 | B2 |
6955716 | Xu et al. | Oct 2005 | B2 |
6976987 | Flores | Dec 2005 | B2 |
6979312 | Shimada | Dec 2005 | B2 |
6979352 | Reynolds | Dec 2005 | B2 |
6981981 | Reiley et al. | Jan 2006 | B2 |
6991616 | Bencini et al. | Jan 2006 | B2 |
6998128 | Haggard et al. | Feb 2006 | B2 |
7004930 | Marshall | Feb 2006 | B2 |
7004945 | Boyd et al. | Feb 2006 | B2 |
7008433 | Voellmicke et al. | Mar 2006 | B2 |
7018460 | Xu et al. | Mar 2006 | B2 |
7022133 | Yee et al. | Apr 2006 | B2 |
7029468 | Honebrink | Apr 2006 | B2 |
7044954 | Reiley et al. | May 2006 | B2 |
7059330 | Makower et al. | Jun 2006 | B1 |
7063682 | Whayne et al. | Jun 2006 | B1 |
7066942 | Treace | Jun 2006 | B2 |
RE39196 | Ying et al. | Jul 2006 | E |
7077842 | Cosman | Jul 2006 | B1 |
7081122 | Reiley et al. | Jul 2006 | B1 |
7081161 | Genge et al. | Jul 2006 | B2 |
7091258 | Neubert et al. | Aug 2006 | B2 |
7091260 | Kūhn | Aug 2006 | B2 |
7094202 | Nobis et al. | Aug 2006 | B2 |
7094286 | Liu | Aug 2006 | B2 |
7108696 | Daniel et al. | Sep 2006 | B2 |
7109254 | Müller et al. | Sep 2006 | B2 |
7112205 | Carrison | Sep 2006 | B2 |
7114501 | Johnson et al. | Oct 2006 | B2 |
7138442 | Smith et al. | Nov 2006 | B2 |
7153306 | Ralph et al. | Dec 2006 | B2 |
7153307 | Scribner et al. | Dec 2006 | B2 |
7156843 | Skarda | Jan 2007 | B2 |
7156845 | Mulier | Jan 2007 | B2 |
7160296 | Pearson et al. | Jan 2007 | B2 |
7166121 | Reiley et al. | Jan 2007 | B2 |
7172629 | McKay et al. | Feb 2007 | B2 |
7179255 | Lettice et al. | Feb 2007 | B2 |
7186234 | Dahla et al. | Mar 2007 | B2 |
7186761 | Soffiati et al. | Mar 2007 | B2 |
7226481 | Kuslich et al. | Jun 2007 | B2 |
7238184 | Megerman et al. | Jul 2007 | B2 |
7252671 | Scribner et al. | Aug 2007 | B2 |
7267683 | Sharkey et al. | Sep 2007 | B2 |
7270661 | Dahla et al. | Sep 2007 | B2 |
7294127 | Leung | Nov 2007 | B2 |
7465318 | Sennett et al. | Dec 2008 | B2 |
7480533 | Cosman et al. | Jan 2009 | B2 |
7503920 | Siegal | Mar 2009 | B2 |
7544196 | Bagga et al. | Jun 2009 | B2 |
7559932 | Truckai et al. | Jul 2009 | B2 |
7569054 | Michelson | Aug 2009 | B2 |
7572263 | Preissman | Aug 2009 | B2 |
7591822 | Olson, Jr. et al. | Sep 2009 | B2 |
7625364 | Corcoran et al. | Dec 2009 | B2 |
7641664 | Pagano | Jan 2010 | B2 |
7731720 | Sand et al. | Jun 2010 | B2 |
7811291 | Liu et al. | Oct 2010 | B2 |
7824403 | Vaska | Nov 2010 | B2 |
7842041 | Liu et al. | Nov 2010 | B2 |
7887543 | Sand et al. | Feb 2011 | B2 |
7905884 | Simonton et al. | Mar 2011 | B2 |
7918874 | Siegal | Apr 2011 | B2 |
7972340 | Sand et al. | Jul 2011 | B2 |
7976542 | Cosman | Jul 2011 | B1 |
8034071 | Scribner et al. | Oct 2011 | B2 |
8246627 | Vanleeuwen et al. | Aug 2012 | B2 |
8284128 | Kimura | Oct 2012 | B2 |
8518036 | Leung | Aug 2013 | B2 |
8583260 | Knudson | Nov 2013 | B2 |
8591507 | Kramer et al. | Nov 2013 | B2 |
8663226 | Germain | Mar 2014 | B2 |
8701675 | Schenker et al. | Apr 2014 | B1 |
RE44883 | Cha | May 2014 | E |
8758349 | Germain et al. | Jun 2014 | B2 |
8827981 | Liu et al. | Sep 2014 | B2 |
8864760 | Kramer et al. | Oct 2014 | B2 |
8936631 | Nguyen | Jan 2015 | B2 |
9113974 | Germain | Aug 2015 | B2 |
9125671 | Germain et al. | Sep 2015 | B2 |
9161809 | Germain et al. | Oct 2015 | B2 |
9421057 | Germain | Aug 2016 | B2 |
9743938 | Germain et al. | Aug 2017 | B2 |
10660656 | Purdy | May 2020 | B2 |
20010011174 | Reiley et al. | Aug 2001 | A1 |
20010023349 | Van Tassel et al. | Sep 2001 | A1 |
20020007180 | Wittenberger et al. | Jan 2002 | A1 |
20020013600 | Scribner et al. | Jan 2002 | A1 |
20020016583 | Cragg | Feb 2002 | A1 |
20020026195 | Layne et al. | Feb 2002 | A1 |
20020026197 | Foley et al. | Feb 2002 | A1 |
20020068929 | Zvuloni | Jun 2002 | A1 |
20020068974 | Kuslich et al. | Jun 2002 | A1 |
20020077595 | Hundertmark et al. | Jun 2002 | A1 |
20020082605 | Reiley et al. | Jun 2002 | A1 |
20020115742 | Trieu et al. | Aug 2002 | A1 |
20020128638 | Chauvel et al. | Sep 2002 | A1 |
20020133148 | Daniel et al. | Sep 2002 | A1 |
20020156483 | Voellmicke et al. | Oct 2002 | A1 |
20020188299 | Reiley et al. | Dec 2002 | A1 |
20020188300 | Arramon et al. | Dec 2002 | A1 |
20030014094 | Hammack et al. | Jan 2003 | A1 |
20030032929 | McGuckin | Feb 2003 | A1 |
20030036763 | Bhatnagar et al. | Feb 2003 | A1 |
20030043963 | Yamagami et al. | Mar 2003 | A1 |
20030050644 | Boucher et al. | Mar 2003 | A1 |
20030069522 | Jasobsen et al. | Apr 2003 | A1 |
20030073979 | Naimark et al. | Apr 2003 | A1 |
20030130664 | Boucher et al. | Jul 2003 | A1 |
20030163085 | Tanner et al. | Aug 2003 | A1 |
20030171744 | Leung et al. | Sep 2003 | A1 |
20030191489 | Reiley et al. | Oct 2003 | A1 |
20030195547 | Scribner et al. | Oct 2003 | A1 |
20030212394 | Pearson et al. | Nov 2003 | A1 |
20030212395 | Woloszko et al. | Nov 2003 | A1 |
20030220414 | Axen et al. | Nov 2003 | A1 |
20030225432 | Baptiste et al. | Dec 2003 | A1 |
20030233096 | Osorio et al. | Dec 2003 | A1 |
20040023384 | Fukaya | Feb 2004 | A1 |
20040023784 | Yu et al. | Feb 2004 | A1 |
20040024081 | Trieu et al. | Feb 2004 | A1 |
20040024398 | Hovda et al. | Feb 2004 | A1 |
20040024409 | Sand et al. | Feb 2004 | A1 |
20040024410 | Olson et al. | Feb 2004 | A1 |
20040034384 | Fukaya | Feb 2004 | A1 |
20040044096 | Smith et al. | Mar 2004 | A1 |
20040044350 | Martin et al. | Mar 2004 | A1 |
20040059328 | Daniel et al. | Mar 2004 | A1 |
20040087936 | Stern et al. | May 2004 | A1 |
20040087994 | Suddaby | May 2004 | A1 |
20040092946 | Bagga et al. | May 2004 | A1 |
20040097612 | Rosenberg et al. | May 2004 | A1 |
20040111136 | Sharkey et al. | Jun 2004 | A1 |
20040127987 | Evans et al. | Jul 2004 | A1 |
20040133208 | Weikel et al. | Jul 2004 | A1 |
20040138758 | Evans et al. | Jul 2004 | A1 |
20040153064 | Foley et al. | Aug 2004 | A1 |
20040153115 | Reiley et al. | Aug 2004 | A1 |
20040158237 | Abboud et al. | Aug 2004 | A1 |
20040167561 | Boucher et al. | Aug 2004 | A1 |
20040167562 | Osorio et al. | Aug 2004 | A1 |
20040167625 | Beyar et al. | Aug 2004 | A1 |
20040210231 | Broucher et al. | Oct 2004 | A1 |
20040215343 | Hochschuler et al. | Oct 2004 | A1 |
20040220577 | Cragg | Nov 2004 | A1 |
20040220680 | Yamamoto et al. | Nov 2004 | A1 |
20040225296 | Reiss et al. | Nov 2004 | A1 |
20040226479 | Lyles et al. | Nov 2004 | A1 |
20040230309 | Dimauro et al. | Nov 2004 | A1 |
20040236186 | Chu | Nov 2004 | A1 |
20040247644 | Bratt et al. | Dec 2004 | A1 |
20040267271 | Scribner et al. | Dec 2004 | A9 |
20050027245 | Sachdeva et al. | Feb 2005 | A1 |
20050033303 | Chappuis et al. | Feb 2005 | A1 |
20050038383 | Kelley et al. | Feb 2005 | A1 |
20050038422 | Maurice | Feb 2005 | A1 |
20050043737 | Reiley et al. | Feb 2005 | A1 |
20050055030 | Falahee | Mar 2005 | A1 |
20050060030 | Lashinski et al. | Mar 2005 | A1 |
20050070844 | Chow et al. | Mar 2005 | A1 |
20050070912 | Voellmicke | Mar 2005 | A1 |
20050070915 | Mazzuca et al. | Mar 2005 | A1 |
20050090852 | Layne et al. | Apr 2005 | A1 |
20050113836 | Lozier et al. | May 2005 | A1 |
20050119650 | Sanders et al. | Jun 2005 | A1 |
20050124989 | Suddaby | Jun 2005 | A1 |
20050143827 | Globerman et al. | Jun 2005 | A1 |
20050177168 | Brunnett et al. | Aug 2005 | A1 |
20050177210 | Lueng et al. | Aug 2005 | A1 |
20050182412 | Johnson et al. | Aug 2005 | A1 |
20050182413 | Johnson et al. | Aug 2005 | A1 |
20050187556 | Stack et al. | Aug 2005 | A1 |
20050199156 | Khairoun et al. | Sep 2005 | A1 |
20050209557 | Carroll et al. | Sep 2005 | A1 |
20050216018 | Sennett | Sep 2005 | A1 |
20050228391 | Levy et al. | Oct 2005 | A1 |
20050234425 | Miller et al. | Oct 2005 | A1 |
20050240193 | Layne et al. | Oct 2005 | A1 |
20050251266 | Maspero et al. | Nov 2005 | A1 |
20050251267 | Winterbottom et al. | Nov 2005 | A1 |
20050261683 | Veldhuizen et al. | Nov 2005 | A1 |
20050283148 | Janssen | Dec 2005 | A1 |
20050287771 | Seamons et al. | Dec 2005 | A1 |
20060024348 | Engqvist et al. | Feb 2006 | A1 |
20060025763 | Nelson et al. | Feb 2006 | A1 |
20060041033 | Bisig et al. | Feb 2006 | A1 |
20060052743 | Reynolds | Mar 2006 | A1 |
20060064101 | Arramon | Mar 2006 | A1 |
20060074433 | McGill et al. | Apr 2006 | A1 |
20060084977 | Lieberman | Apr 2006 | A1 |
20060085009 | Truckai et al. | Apr 2006 | A1 |
20060100635 | Reiley et al. | May 2006 | A1 |
20060100706 | Shadduck et al. | May 2006 | A1 |
20060106392 | Embry | May 2006 | A1 |
20060106459 | Truckai et al. | May 2006 | A1 |
20060116689 | Albans et al. | Jun 2006 | A1 |
20060116690 | Pagano | Jun 2006 | A1 |
20060122623 | Truckai et al. | Jun 2006 | A1 |
20060142732 | Karmarkar et al. | Jun 2006 | A1 |
20060149268 | Truckai et al. | Jul 2006 | A1 |
20060149281 | Reiley et al. | Jul 2006 | A1 |
20060156959 | Engqvist et al. | Jul 2006 | A1 |
20060184106 | McDaniel et al. | Aug 2006 | A1 |
20060184192 | Markworth et al. | Aug 2006 | A1 |
20060200121 | Mowery | Sep 2006 | A1 |
20060206116 | Yeung | Sep 2006 | A1 |
20060206136 | Sachdeva et al. | Sep 2006 | A1 |
20060217704 | Cockburn et al. | Sep 2006 | A1 |
20060217736 | Kaneko | Sep 2006 | A1 |
20060229625 | Truckai et al. | Oct 2006 | A1 |
20060229631 | Reiley et al. | Oct 2006 | A1 |
20060235417 | Sala | Oct 2006 | A1 |
20060259023 | Abboud et al. | Nov 2006 | A1 |
20060264819 | Fischer et al. | Nov 2006 | A1 |
20060264945 | Edidin et al. | Nov 2006 | A1 |
20060266372 | Miller et al. | Nov 2006 | A1 |
20060270750 | Almen et al. | Nov 2006 | A1 |
20060271061 | Beyar et al. | Nov 2006 | A1 |
20060276797 | Botimer | Dec 2006 | A1 |
20060276819 | Osorio et al. | Dec 2006 | A1 |
20060293687 | Bogert | Dec 2006 | A1 |
20070006692 | Phan | Jan 2007 | A1 |
20070010845 | Gong et al. | Jan 2007 | A1 |
20070016130 | Leeflang et al. | Jan 2007 | A1 |
20070016211 | Botimer | Jan 2007 | A1 |
20070021769 | Scribner et al. | Jan 2007 | A1 |
20070043373 | Sala | Feb 2007 | A1 |
20070055201 | Seto et al. | Mar 2007 | A1 |
20070055260 | Cragg | Mar 2007 | A1 |
20070055266 | Osorio et al. | Mar 2007 | A1 |
20070055275 | Schaller | Mar 2007 | A1 |
20070055277 | Osorio et al. | Mar 2007 | A1 |
20070055278 | Osorio et al. | Mar 2007 | A1 |
20070055279 | Sand et al. | Mar 2007 | A1 |
20070055281 | Osorio et al. | Mar 2007 | A1 |
20070055283 | Scribner | Mar 2007 | A1 |
20070055284 | Osorio | Mar 2007 | A1 |
20070055285 | Osorio et al. | Mar 2007 | A1 |
20070055300 | Osorio et al. | Mar 2007 | A1 |
20070055382 | Osorio et al. | Mar 2007 | A1 |
20070059281 | Moseley et al. | Mar 2007 | A1 |
20070067034 | Chirico et al. | Mar 2007 | A1 |
20070093840 | Pacelli | Apr 2007 | A1 |
20070114248 | Kovac | May 2007 | A1 |
20070118142 | Krueger et al. | May 2007 | A1 |
20070118143 | Ralph et al. | May 2007 | A1 |
20070142842 | Krueger et al. | Jun 2007 | A1 |
20070156130 | Thistle | Jul 2007 | A1 |
20070162042 | Dunker | Jul 2007 | A1 |
20070173939 | Kim et al. | Jul 2007 | A1 |
20070185231 | Liu et al. | Aug 2007 | A1 |
20070197935 | Reiley | Aug 2007 | A1 |
20070198023 | Sand et al. | Aug 2007 | A1 |
20070203500 | Gordon | Aug 2007 | A1 |
20070211563 | Devries | Sep 2007 | A1 |
20070233146 | Henniges et al. | Oct 2007 | A1 |
20070260223 | Scheibe et al. | Nov 2007 | A1 |
20070260257 | Phan | Nov 2007 | A1 |
20070270876 | Kuo et al. | Nov 2007 | A1 |
20070276319 | Betts | Nov 2007 | A1 |
20070282305 | Goldfarb et al. | Dec 2007 | A1 |
20080004615 | Woloszko et al. | Jan 2008 | A1 |
20080015664 | Podjajsky | Jan 2008 | A1 |
20080033422 | Turner et al. | Feb 2008 | A1 |
20080058725 | Scribner et al. | Mar 2008 | A1 |
20080058821 | Maurer et al. | Mar 2008 | A1 |
20080058827 | Osorio et al. | Mar 2008 | A1 |
20080058840 | Albrecht | Mar 2008 | A1 |
20080065020 | Ralph et al. | Mar 2008 | A1 |
20080065087 | Osorio et al. | Mar 2008 | A1 |
20080065190 | Osorio et al. | Mar 2008 | A1 |
20080086142 | Kohm et al. | Apr 2008 | A1 |
20080125775 | Morris | May 2008 | A1 |
20080140079 | Osorio et al. | Jun 2008 | A1 |
20080183165 | Buysee et al. | Jul 2008 | A1 |
20080183265 | Bly | Jul 2008 | A1 |
20080195112 | Liu et al. | Aug 2008 | A1 |
20080208255 | Siegal | Aug 2008 | A1 |
20080221608 | Betts | Sep 2008 | A1 |
20080228192 | Beyer et al. | Sep 2008 | A1 |
20080249481 | Crainich | Oct 2008 | A1 |
20080249525 | Lee et al. | Oct 2008 | A1 |
20080255571 | Truckai et al. | Oct 2008 | A1 |
20080269766 | Justis | Oct 2008 | A1 |
20080269796 | Reiley et al. | Oct 2008 | A1 |
20080287741 | Ostrovsky et al. | Nov 2008 | A1 |
20080294167 | Schumacher et al. | Nov 2008 | A1 |
20090076517 | Reiley et al. | Mar 2009 | A1 |
20090105775 | Mitchell et al. | Apr 2009 | A1 |
20090131867 | Liu et al. | May 2009 | A1 |
20090131886 | Liu et al. | May 2009 | A1 |
20090131945 | Liu et al. | May 2009 | A1 |
20090131948 | Liu | May 2009 | A1 |
20090131950 | Liu et al. | May 2009 | A1 |
20090131986 | Lee | May 2009 | A1 |
20090182427 | Liu et al. | Jul 2009 | A1 |
20090198243 | Melsheimer | Aug 2009 | A1 |
20090264862 | Neidert et al. | Oct 2009 | A1 |
20090264892 | Beyar et al. | Oct 2009 | A1 |
20090292289 | Sand et al. | Nov 2009 | A9 |
20090293687 | Nino et al. | Dec 2009 | A1 |
20090299282 | Lau et al. | Dec 2009 | A1 |
20100057087 | Cha | Mar 2010 | A1 |
20100076476 | To et al. | Mar 2010 | A1 |
20100082033 | Germain | Apr 2010 | A1 |
20100114184 | Degtyar | May 2010 | A1 |
20100121332 | Crainich et al. | May 2010 | A1 |
20100152724 | Marion et al. | Jun 2010 | A1 |
20100160922 | Liu et al. | Jun 2010 | A1 |
20100211076 | Germain et al. | Aug 2010 | A1 |
20100274270 | Patel | Oct 2010 | A1 |
20100298832 | Lau et al. | Nov 2010 | A1 |
20110034884 | Pellegrino et al. | Feb 2011 | A9 |
20110098701 | McIntyre et al. | Apr 2011 | A1 |
20110160737 | Steffen et al. | Jun 2011 | A1 |
20110251615 | Truckai et al. | Oct 2011 | A1 |
20110295261 | Germain | Dec 2011 | A1 |
20110295262 | Germain et al. | Dec 2011 | A1 |
20110301590 | Podhajsky et al. | Dec 2011 | A1 |
20120065543 | Ireland | Mar 2012 | A1 |
20120130381 | Germain | May 2012 | A1 |
20120143298 | Just et al. | Jun 2012 | A1 |
20120158004 | Burger et al. | Jun 2012 | A1 |
20120191095 | Burger et al. | Jul 2012 | A1 |
20120232553 | Bloom et al. | Sep 2012 | A1 |
20120239049 | Truckai | Sep 2012 | A1 |
20120265186 | Burger et al. | Oct 2012 | A1 |
20120277582 | Mafi | Nov 2012 | A1 |
20120277730 | Salahieh | Nov 2012 | A1 |
20120330180 | Pellegrino et al. | Dec 2012 | A1 |
20120330301 | Pellegrino et al. | Dec 2012 | A1 |
20130006232 | Pellegrino | Jan 2013 | A1 |
20130006257 | Lee | Jan 2013 | A1 |
20130041377 | Kuntz | Feb 2013 | A1 |
20130072941 | Tan-Malecki et al. | Mar 2013 | A1 |
20130231654 | Germain | Sep 2013 | A1 |
20130237795 | Carr | Sep 2013 | A1 |
20130261615 | Kramer et al. | Oct 2013 | A1 |
20130261621 | Kramer et al. | Oct 2013 | A1 |
20130345709 | Burger et al. | Dec 2013 | A1 |
20140135779 | Germain | May 2014 | A1 |
20140163566 | Phan et al. | Jun 2014 | A1 |
20140236144 | Krueger et al. | Aug 2014 | A1 |
20140257046 | Steven | Sep 2014 | A1 |
20140316413 | Burger et al. | Oct 2014 | A1 |
20140350542 | Kramer et al. | Nov 2014 | A1 |
20140371740 | Germain et al. | Dec 2014 | A1 |
20150216594 | Prakash | Aug 2015 | A1 |
20150265333 | Shin et al. | Sep 2015 | A1 |
20150297246 | Patel | Oct 2015 | A1 |
20150313614 | Germain | Nov 2015 | A1 |
20160066984 | Janssen et al. | Mar 2016 | A1 |
20160228131 | Brockman et al. | Aug 2016 | A1 |
20160310193 | Lv et al. | Oct 2016 | A1 |
20160331443 | Phan et al. | Nov 2016 | A1 |
20170095291 | Harrington | Apr 2017 | A1 |
20170105798 | Allison | Apr 2017 | A1 |
20180078170 | Panescu et al. | Mar 2018 | A1 |
20180147006 | Purdy et al. | May 2018 | A1 |
20180147007 | Purdy et al. | May 2018 | A1 |
20190357971 | Adi et al. | Nov 2019 | A1 |
20200078066 | Purdy et al. | Mar 2020 | A1 |
20200146743 | Defosset et al. | May 2020 | A1 |
20200146744 | Defosset et al. | May 2020 | A1 |
20200390449 | Purdy et al. | Dec 2020 | A1 |
20210236200 | McGregor et al. | Aug 2021 | A1 |
20210401496 | Purdy et al. | Dec 2021 | A1 |
Number | Date | Country |
---|---|---|
2785207 | Jul 2011 | CA |
88203061 | Nov 1988 | CN |
2841051 | Nov 2006 | CN |
102500036 | Jun 2012 | CN |
19739699 | Mar 1999 | DE |
20314010 | Jan 2015 | DE |
1459691 | Sep 2004 | EP |
1927375 | Jun 2008 | EP |
3544535 | Oct 2019 | EP |
2004242936 | Sep 2004 | JP |
2008510530 | Apr 2008 | JP |
2008528081 | Jul 2008 | JP |
2008541878 | Nov 2008 | JP |
2010063887 | Mar 2010 | JP |
2011500156 | Jan 2011 | JP |
101342906 | Dec 2013 | KR |
1993004634 | Mar 1993 | WO |
1996013297 | May 1996 | WO |
1996020752 | Jul 1996 | WO |
1997003611 | Feb 1997 | WO |
2002003870 | Jan 2002 | WO |
2003101308 | Dec 2003 | WO |
2005039390 | May 2005 | WO |
2005122938 | Dec 2005 | WO |
2006058223 | Jun 2006 | WO |
2007036815 | Apr 2007 | WO |
2007087400 | Aug 2007 | WO |
2008076330 | Jun 2008 | WO |
2008084479 | Jul 2008 | WO |
2009155319 | Dec 2009 | WO |
2010039894 | Apr 2010 | WO |
2010081187 | Jul 2010 | WO |
2010135602 | Nov 2010 | WO |
2010135606 | Nov 2010 | WO |
2011066465 | Jun 2011 | WO |
2011114602 | Sep 2011 | WO |
2011137357 | Nov 2011 | WO |
2011137377 | Nov 2011 | WO |
2012071464 | May 2012 | WO |
2012142217 | Oct 2012 | WO |
2013147990 | Oct 2013 | WO |
2014093673 | Jun 2014 | WO |
2015051070 | Apr 2015 | WO |
2016183178 | Nov 2016 | WO |
2018116222 | Jun 2018 | WO |
Entry |
---|
US 7,063,700 B2, 06/2006, Michelson (withdrawn) |
Office Action dated Nov. 27, 2020 for U.S. Appl. No. 15/822,944. |
Notice of Allowance dated Mar. 31, 2021 for U.S. Appl. No. 15/822,864. |
European Examination Report dated Jan. 27, 2022 for EP18180753.8. |
European Search Report dated Jul. 7, 2021 for EP16793433.0. |
Extended European Search Report dated Jun. 30, 2022 for EP19882877.4. |
Notice of Allowance dated Feb. 7, 2022 for U.S. Appl. No. 16/680,056. |
Office Action dated Jan. 12, 2022 for U.S. Appl. No. 16/677,216. |
Office Action dated Nov. 29, 2021 for U.S. Appl. No. 16/677,124. |
Notice of Allowance dated May 27, 2021 for U.S. Appl. No. 15/822,944. |
Office Action dated May 7, 2021 for U.S. Appl. No. 16/417,502. |
Office Action dated Mar. 1, 2017 for U.S. Appl. No. 15/211,359. |
Office Action dated Mar. 21, 2011 for U.S. Appl. No. 11/941,764. |
Office Action dated Mar. 21, 2011 for U.S. Appl. No. 12/029,428. |
Office Action dated Apr. 19, 2018 for U.S. Appl. No. 15/388,598. |
Office Action dated Apr. 24, 2017 for U.S. Appl. No. 14/453,427. |
Office Action dated Apr. 26, 2010 for U.S. Appl. No. 12/029,428. |
Office Action dated May 1, 2009 for U.S. Appl. No. 12/261,987. |
Office Action dated May 5, 2010 for U.S. Appl. No. 11/941,764. |
Office Action dated May 6, 2019 for U.S. Appl. No. 15/675,315. |
Office Action dated May 13, 2009 for U.S. Appl. No. 12/029,428. |
Office Action dated May 17, 2010 for U.S. Appl. No. 12/261,987. |
Office Action dated May 21, 2014 for U.S. Appl. No. 13/098,116. |
Office Action dated May 24, 2012 for U.S. Appl. No. 12/578,455. |
Office Action dated May 31, 2016 for U.S. Appl. No. 14/815,620. |
Office Action dated Jun. 4, 2018 for U.S. Appl. No. 15/349,715. |
Office Action dated Jun. 8, 2009 for U.S. Appl. No. 11/941,764. |
Office Action dated Jun. 10, 2020 for U.S. Appl. No. 15/822,944. |
Office Action dated Jun. 11, 2020 for U.S. Appl. No. 15/822,864. |
Office Action dated Jun. 12, 2009 for U.S. Appl. No. 11/941,733. |
Office Action dated Jun. 21, 2013 for U.S. Appl. No. 13/215,098. |
Office Action dated Jun. 22, 2018 for U.S. Appl. No. 15/917,454. |
Office Action dated Jun. 25, 2015 for U.S. Appl. No. 13/853,397. |
Office Action dated Jun. 29, 2018 for U.S. Appl. No. 15/449,591. |
Office Action dated Jul. 11, 2017 for U.S. Appl. No. 14/815,812. |
Office Action dated Jul. 12, 2010 for U.S. Appl. No. 11/941,764. |
Office Action dated Jul. 12, 2017 for U.S. Appl. No. 13/083,411. |
Office Action dated Jul. 25, 2011 for U.S. Appl. No. 11/941,733. |
Office Action dated Jul. 30, 2013 for U.S. Appl. No. 13/083,411. |
Office Action dated Sep. 1, 2010 for U.S. Appl. No. 12/029,428. |
Office Action dated Sep. 6, 2017 for U.S. Appl. No. 15/211,359. |
Office Action dated Sep. 26, 2017 for U.S. Appl. No. 15/388,598. |
Office Action dated Oct. 2, 2018 for U.S. Appl. No. 14/139,372. |
Office Action dated Oct. 30, 2018 for U.S. Appl. No. 15/349,715. |
Office Action dated Nov. 3, 2008 for U.S. Appl. No. 11/941,764. |
Office Action dated Nov. 3, 2008 for U.S. Appl. No. 12/029,428. |
Office Action dated Nov. 5, 2008 for U.S. Appl. No. 11/941,733. |
Office Action dated Nov. 7, 2019 for U.S. Appl. No. 15/675,315. |
Office Action dated Nov. 12, 2013 for U.S. Appl. No. 13/083,411. |
Office Action dated Nov. 25, 2016 for U.S. Appl. No. 13/083,411. |
Office Action dated Dec. 2, 2009 for U.S. Appl. No. 12/029,428. |
Office Action dated Dec. 3, 2012 for U.S. Appl. No. 12/571,174. |
Office Action dated Dec. 9, 2009 for U.S. Appl. No. 12/262,064. |
Office Action dated Dec. 11, 2009 for U.S. Appl. No. 12/261,987. |
Office Action dated Dec. 20, 2019 for U.S. Appl. No. 15/862,441. |
Office Action dated Dec. 26, 2019 for U.S. Appl. No. 15/822,864. |
Office Action dated Feb. 27, 2013 for U.S. Appl. No. 12/578,455. |
Office Action dated Jul. 12, 2016 for U.S. Appl. No. 14/887,007. |
Office Action dated Sep. 10, 2013 for U.S. Appl. No. 12/571,174. |
Disc-O-Tech confidence Cement System at http://www.disc-o-tech.com/Articles/Article.asp?CategoryID=4&ArticleID=168 accessed, ,Dec. 3, 2007. |
Dai, et al., Bone-Particle-Impregnated Bone Cement: an in vivo weight-bearing study, Journal Biomedical Materials Search, vol. 25 ,Jul. 30, 1990 ,141-156. |
Hasenwinkel, et al.,“A Novel High-Viscosity, Two-Solution Acrylic Bone Cement: Effect of Chemical Composition on Properties”, J. Biomed Mater. Res. vol. 47, No. 1 ,1999 ,36-45. |
Klawitter, et al., Application of Porous Ceramics for the Attachment of Load Bearing Internal Orthopedic Applications, J. Biomed. Mater. Res. Symp., 2(1) ,1972 ,61-229. |
Liu, et al., Bone-Particle-Impregnanted Bone Cement: An In Vitro Study, Journal of Biomedical Materials Research, vol. 21 ,1987 ,247-261. |
Park, et al., Biomaterials: An Introduction—Second Edition, Plenum Press ,1992 ,177-178. |
Park, et al., The Materials Properties of Bone-Particle Impregnated PMMA, Journal of Biomedical Engineering, vol. 108 ,1986 ,141-148. |
European Search Report dated Jul. 15, 2020 for EP18736547.3. |
European Examination Report dated Dec. 19, 2017 for EP13767383.6. |
European Search Report dated Jan. 7, 2019 for EP16793433.0. |
European Search Report dated May 29, 2020 for EP17874650.9. |
European Search Report dated Jun. 8, 2017 for EP17154660.9. |
European Search Report dated Jun. 16, 2020 for EP17863626.2. |
European Search Report dated Jul. 1, 2020 for EP17878602.6. |
European Search Report dated Nov. 15, 2017 for EP09818476.5. |
European Search Report dated Nov. 16, 2016 for EP14772615.2. |
International Search Report and Written Opinion dated Jan. 9, 2012 for PCT/US2011/034185. |
International Search Report and Written Opinion dated Jan. 22, 2009 for PCT/US2008/83698. |
International Search Report and Written Opinion dated Feb. 7, 2018 for PCT/US2017/058303. |
International Search Report and Written Opinion dated Feb. 21, 2018 for PCT/US2017/063281. |
International Search Report and Written Opinion dated Mar. 30, 2018 for PCT/US2017/065328. |
International Search Report and Written Opinion dated Apr. 8, 2020 for PCT/US2019/060273. |
International Search Report and Written Opinion dated Apr. 8, 2020 for PCT/US2019060279. |
International Search Report and Written Opinion dated Apr. 23, 2016 for PCT/US2018/012372. |
International Search Report and Written Opinion dated Jul. 20, 2010 for PCT/US2010/035687. |
International Search Report and Written Opinion dated Jul. 26, 2011 for PCT/US2011/034628. |
International Search Report and Written Opinion dated Aug. 25, 2009 for PCT/US2009/035726. |
International Search Report and Written Opinion dated Nov. 20, 2009 for PCT/US2009/059113. |
Notice of Allowance dated Jan. 4, 2017 for U.S. Appl. No. 13/302,927. |
Notice of Allowance dated Jan. 18, 2017 for U.S. Appl. No. 13/097,998. |
Notice of Allowance dated Feb. 19, 2020 for U.S. Appl. No. 15/675,315. |
Notice of Allowance dated Feb. 21, 2019 for U.S. Appl. No. 14/139,372. |
Notice of Allowance dated Apr. 3, 2019 for U.S. Appl. No. 15/349,715. |
Notice of Allowance dated Apr. 9, 2014 for U.S. Appl. No. 12/578,455. |
Notice of Allowance dated Apr. 23, 2018 for U.S. Appl. No. 13/083,411. |
Notice of Allowance dated May 3, 2017 for U.S, U.S. Appl. No. 14/815,620. |
Notice of Allowance dated May 11, 2018 for U.S. Application No. 14/453,427. |
Notice of Allowance dated May 26, 2015 for U.S. Appl. No. 13/098,116. |
Notice of Allowance dated Aug. 8, 2019 for U.S. Appl. No. 15/836,125. |
Notice of Allowance dated Aug. 9, 2019 for U.S. Appl. No. 15/836,241. |
Notice of Allowance dated Aug. 24, 2018 for U.S. Appl. No. 15/388,598. |
Notice of Allowance dated Sep. 20, 2019 for U.S. Appl. No. 15/793,509. |
Notice of Allowance dated Oct. 28, 2016 for U.S. Appl. No. 13/853,397. |
Notice of Allowance dated Nov. 8, 2013 for U.S. Appl. No. 12/578,455. |
Notice of Allowance dated Nov. 9, 2017 for U.S. Appl. No. 14/815,812. |
Notice of Allowance dated Nov. 18, 2016 for U.S. Appl. No. 13/097,998. |
Notice of Allowance dated Nov. 25, 2013 for U.S. Appl. No. 12/571,174. |
Notice of Allowance dated Nov. 25, 2016 for U.S. Appl. No. 13/853,397. |
Notice of Allowance dated Dec. 13, 2018 for U.S. Appl. No. 15/917,454. |
Notice of Allowance dated Dec. 28, 2017 for U.S. Appl. No. 15/211,359. |
Office Action dated Jan. 18, 2017 for U.S. Appl. No. 14/815,620. |
Office Action dated Jan. 26, 2011 for U.S. Appl. No. 11/941,764. |
Office Action dated Jan. 26, 2017 for U.S. Appl. No. 14/815,812. |
Office Action dated Feb. 3, 2016 for U.S. Appl. No. 13/853,397. |
Office Action dated Feb. 10, 2015 for U.S. Appl. No. 13/083,411. |
Office Action dated Feb. 23, 2010 for U.S. Appl. No. 11/941,733. |
Office Action dated Feb. 23, 2010 for U.S. Appl. No. 11/941,764. |
European Examination Report dated Sep. 30, 2022 for EP 17863626.2. |
Extended European Search Report dated Sep. 13, 2022 for EP19881354.5. |
Notice of Allowance dated Jul. 14, 2022 for U.S. Appl. No. 16/677,216. |
Notice of Allowance dated Sep. 1, 2022 for U.S. Appl. No. 16/673,707. |
Notice of Allowance dated Aug. 31, 2016 for U.S. Appl. No. 14/887,007. |
Office Action dated Apr. 13, 2022 for U.S. Appl. No. 16/673,707. |
Office Action dated Jul. 29, 2013 for U.S. Appl. No. 13/098,116. |
Office Action dated Oct. 19, 2022 for U.S. Appl. No. 16/677,124. |
Number | Date | Country | |
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20200390449 A1 | Dec 2020 | US |
Number | Date | Country | |
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62443371 | Jan 2017 | US |
Number | Date | Country | |
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Parent | 15862441 | Jan 2018 | US |
Child | 16881927 | US |